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Search of human proteins with 6912398
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912398 general transcription factor IIIC, polypeptide 3,
102kDa [Homo sapiens]
(886 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912398 general transcription factor IIIC, polypeptide 3, 102... 1757 0.0
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 62 3e-09
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 62 3e-09
gi|17975763 myelin transcription factor 1 [Homo sapiens] 55 4e-07
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 54 5e-07
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 53 1e-06
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 53 1e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 50 7e-06
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 49 2e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 49 2e-05
gi|83415184 transmembrane and tetratricopeptide repeat containin... 48 4e-05
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 48 5e-05
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 48 5e-05
gi|21735569 claspin [Homo sapiens] 47 6e-05
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 47 8e-05
gi|55741677 SET domain containing 1A [Homo sapiens] 47 8e-05
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 47 8e-05
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 47 1e-04
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 47 1e-04
gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 47 1e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 47 1e-04
gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens] 46 2e-04
gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens] 46 2e-04
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 46 2e-04
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 46 2e-04
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 46 2e-04
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 46 2e-04
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 46 2e-04
gi|21735415 centromere protein B [Homo sapiens] 45 2e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 45 2e-04
>gi|6912398 general transcription factor IIIC, polypeptide 3, 102kDa
[Homo sapiens]
Length = 886
Score = 1757 bits (4551), Expect = 0.0
Identities = 886/886 (100%), Positives = 886/886 (100%)
Query: 1 MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGIN 60
MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGIN
Sbjct: 1 MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGIN 60
Query: 61 STKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
STKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD
Sbjct: 61 STKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
Query: 121 VFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAP 180
VFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAP
Sbjct: 121 VFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAP 180
Query: 181 LAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCY 240
LAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCY
Sbjct: 181 LAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCY 240
Query: 241 TKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSY 300
TKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSY
Sbjct: 241 TKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSY 300
Query: 301 YEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKK 360
YEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKK
Sbjct: 301 YEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKK 360
Query: 361 TSEEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDM 420
TSEEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDM
Sbjct: 361 TSEEGTSEENKAPENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDM 420
Query: 421 GDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYG 480
GDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYG
Sbjct: 421 GDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAVVWLRHAECLKALGYMERAAESYG 480
Query: 481 KVVDLAPLHLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHRS 540
KVVDLAPLHLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHRS
Sbjct: 481 KVVDLAPLHLDARISLSTLQQQLGQPEKALEALEPMYDPDTLAQDANAAQQELKLLLHRS 540
Query: 541 TLLFSQGKMYGYVDTLLTMLAMLLKVAMNRAQVCLISSSKSGERHLYLIKVSRDKISDSN 600
TLLFSQGKMYGYVDTLLTMLAMLLKVAMNRAQVCLISSSKSGERHLYLIKVSRDKISDSN
Sbjct: 541 TLLFSQGKMYGYVDTLLTMLAMLLKVAMNRAQVCLISSSKSGERHLYLIKVSRDKISDSN 600
Query: 601 DQESANCDAKAIFAVLTSVLTKDDWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYD 660
DQESANCDAKAIFAVLTSVLTKDDWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYD
Sbjct: 601 DQESANCDAKAIFAVLTSVLTKDDWWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYD 660
Query: 661 DRQKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHR 720
DRQKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHR
Sbjct: 661 DRQKRKELEYFGLSAAILDKNFRKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHR 720
Query: 721 FCLRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHM 780
FCLRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHM
Sbjct: 721 FCLRLMLKNPENHALCVLNGHNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHM 780
Query: 781 ASQKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALEL 840
ASQKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALEL
Sbjct: 781 ASQKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALEL 840
Query: 841 PPLVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI 886
PPLVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI
Sbjct: 841 PPLVVEGIELDQLDLRRDIAYNLSLIYQSSGNTGMAQTLLYTYCSI 886
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 61.6 bits (148), Expect = 3e-09
Identities = 55/199 (27%), Positives = 89/199 (44%), Gaps = 21/199 (10%)
Query: 26 EERKTREKKSLQEKGKLSAEENPDDSEVPS--SSGINSTKSQDKDVNEGETSDGV----- 78
EE+KT+ K+ + KG+ + + +DSE SG++ S+ +D T
Sbjct: 1316 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1375
Query: 79 -------------RKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLE 125
R V + +S N ++EEEE+EEEEEEEEEE E+ D
Sbjct: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435
Query: 126 MVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEP 185
++ +K++K+ + R++ AL+ E R A ERE L + I A P
Sbjct: 1436 GKGRKKIRKILKDDKLRTETQNALKE-EEERRKRIAEREREREKLREVIEIEDASPTKCP 1494
Query: 186 FSTLAMIYEDQGDMEKSLQ 204
+T ++ ED+ E +Q
Sbjct: 1495 ITTKLVLDEDEETKEPLVQ 1513
Score = 30.0 bits (66), Expect = 9.9
Identities = 23/95 (24%), Positives = 39/95 (41%), Gaps = 10/95 (10%)
Query: 33 KKSLQEKGKLSAEENPDDSEVPSSSGINS----------TKSQDKDVNEGETSDGVRKSV 82
KK Q + + S ++ + E+ S S I + TK D +E + G+
Sbjct: 767 KKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQG 826
Query: 83 HKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPT 117
HK + + DD E ++E E E T ++ T
Sbjct: 827 HKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDT 861
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 61.6 bits (148), Expect = 3e-09
Identities = 55/199 (27%), Positives = 89/199 (44%), Gaps = 21/199 (10%)
Query: 26 EERKTREKKSLQEKGKLSAEENPDDSEVPS--SSGINSTKSQDKDVNEGETSDGV----- 78
EE+KT+ K+ + KG+ + + +DSE SG++ S+ +D T
Sbjct: 1354 EEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELE 1413
Query: 79 -------------RKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLE 125
R V + +S N ++EEEE+EEEEEEEEEE E+ D
Sbjct: 1414 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1473
Query: 126 MVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEP 185
++ +K++K+ + R++ AL+ E R A ERE L + I A P
Sbjct: 1474 GKGRKKIRKILKDDKLRTETQNALKE-EEERRKRIAEREREREKLREVIEIEDASPTKCP 1532
Query: 186 FSTLAMIYEDQGDMEKSLQ 204
+T ++ ED+ E +Q
Sbjct: 1533 ITTKLVLDEDEETKEPLVQ 1551
Score = 30.0 bits (66), Expect = 9.9
Identities = 23/95 (24%), Positives = 39/95 (41%), Gaps = 10/95 (10%)
Query: 33 KKSLQEKGKLSAEENPDDSEVPSSSGINS----------TKSQDKDVNEGETSDGVRKSV 82
KK Q + + S ++ + E+ S S I + TK D +E + G+
Sbjct: 805 KKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQG 864
Query: 83 HKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPT 117
HK + + DD E ++E E E T ++ T
Sbjct: 865 HKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDT 899
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 54.7 bits (130), Expect = 4e-07
Identities = 37/115 (32%), Positives = 55/115 (47%), Gaps = 23/115 (20%)
Query: 33 KKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGE 92
++S ++KG LS EE ++ E + +++D E E E
Sbjct: 246 EESSKQKGILSHEEEDEEEE-------EEEEEEEEDEEEEEEE----------------E 282
Query: 93 NEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKLPR 147
E++EEEEEEEEEEEEEEE E+ A DV E + +K + + P S P+
Sbjct: 283 EEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPK 337
Score = 49.7 bits (117), Expect = 1e-05
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 10/103 (9%)
Query: 46 ENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEE 105
E+ E GI S + +D++ E E + + E E++EEEEEEEEE
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEE----------EEEEEEEEEEEEEE 290
Query: 106 EEEEEETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKLPRA 148
EEEEEE E+ + +++ +T +K P + P +
Sbjct: 291 EEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPES 333
Score = 46.2 bits (108), Expect = 1e-04
Identities = 29/78 (37%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 38 EKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDE 97
E+G+ P+D+E + + +SQD E + S K S E+E++E
Sbjct: 208 EEGEKGLFIQPEDAEEVVE--VTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEE 265
Query: 98 EEEEEEEEEEEEEETPEQ 115
EEEEEEEE+EEEEE E+
Sbjct: 266 EEEEEEEEDEEEEEEEEE 283
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 54.3 bits (129), Expect = 5e-07
Identities = 32/96 (33%), Positives = 49/96 (51%), Gaps = 13/96 (13%)
Query: 20 EFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVR 79
E E + + E + E G++ E +S+ S+ K+ +K V +G SDG
Sbjct: 799 EAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDG-- 856
Query: 80 KSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQ 115
G++E++EEEEEE+EEEEEEEE E+
Sbjct: 857 -----------GDSEEEEEEEEEQEEEEEEEEQEEE 881
Score = 35.8 bits (81), Expect = 0.18
Identities = 31/117 (26%), Positives = 53/117 (45%), Gaps = 11/117 (9%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
EG+I E+ E + E +T ++ E E D+ V G + S++++ E
Sbjct: 811 EGEIHAEDGEMKGNEGETESQELSAEN---HGEAKNDEKGVEDGGGSDGGDSEEEEEEEE 867
Query: 73 ETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPE--QPTAGDVFVLEMV 127
E + + + E E++EEEEE+ EE + PE Q A +F+L +V
Sbjct: 868 EQEEEEEEEEQEE------EEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLLPIV 918
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Query: 156 ANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPS 215
ANI+ +G EEA+ + + + P S LA + + QG ++++L A ++P+
Sbjct: 324 ANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 383
Query: 216 DTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYR 275
+ + + E +++ A+ CYT+A++ P +S+++ G+ A+ YR
Sbjct: 384 FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYR 443
Query: 276 RILNLLSPSDGERFMQLA 293
L L P + + LA
Sbjct: 444 TALK-LKPDFPDAYCNLA 460
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 10/202 (4%)
Query: 157 NIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSD 216
N+ A G EEA ++ I P +S L ++ QG++ ++ A L+P+
Sbjct: 155 NLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF 214
Query: 217 TEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRR 276
+ ++ L + E +A+ Y +AL P + + +Y + G +A+D YRR
Sbjct: 215 LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRR 274
Query: 277 ILNLLSPSDGERFMQLARDMAK--SYYEAND-VTSAINIIDEAFSKHQGL--VSMEDVNI 331
+ L P + + LA + + S EA D +A+ + L + E NI
Sbjct: 275 AIE-LQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNI 333
Query: 332 AAELYISNKQYDKALEIITDFS 353
+ + Y KALE+ +F+
Sbjct: 334 EEAV----RLYRKALEVFPEFA 351
Score = 47.8 bits (112), Expect = 5e-05
Identities = 75/389 (19%), Positives = 145/389 (37%), Gaps = 75/389 (19%)
Query: 176 IRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQ 235
I+Q PL E +S L +Y+++G ++++++ A L P + ++ LA + +++
Sbjct: 72 IKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEG 131
Query: 236 AIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNL--------------- 280
A+ Y AL+Y P + +L + +G + A Y + +
Sbjct: 132 AVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF 191
Query: 281 -------LSPSDGERFMQLARDMAKSYYEANDVTSAINIIDEAFSKHQGLVSME------ 327
L+ E+ + L + +Y +V I D A + + +S+
Sbjct: 192 NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVV 251
Query: 328 DVNIAAELY------ISNKQYDKALEIITDFSGIV--LEKKTSEEGTSEENKAPENVTCT 379
N+A Y ++ Y +A+E+ F L E+G+ E + N
Sbjct: 252 HGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTA-- 309
Query: 380 IPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQ-NPEDMGDLYLDVAEAFLDVGEYN 438
L +C H + LN L EQ N E+ LY E F + +
Sbjct: 310 ------------LRLCPTH---ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAH 354
Query: 439 SALPLLSALVCSERYNLAVVWLRHAEC-----------------LKALGYMERAAESYGK 481
S L A V ++ L + + E LK + ++ A + Y +
Sbjct: 355 SNL----ASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTR 410
Query: 482 VVDLAPLHLDARISLSTLQQQLGQPEKAL 510
+ + P DA +L+++ + G +A+
Sbjct: 411 AIQINPAFADAHSNLASIHKDSGNIPEAI 439
Score = 44.7 bits (104), Expect = 4e-04
Identities = 77/397 (19%), Positives = 151/397 (38%), Gaps = 75/397 (18%)
Query: 151 GLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAA 210
GL A+ + G+ E A CM++ RQ P L+ I+ +++S F +A
Sbjct: 13 GLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAI 72
Query: 211 HLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMA 270
NP E + L + E+ +++AI Y AL+ +P + ++ GD + A
Sbjct: 73 KQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGA 132
Query: 271 MDGYRRILNLLSPSDGERFMQLARDMAKSYYEANDVTSAINIIDEAFSKHQGLVSMED-- 328
+ Y L Q D+ + ++ A+ ++EA + + + +
Sbjct: 133 VQAYVSAL------------QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNF 180
Query: 329 ----------VNIAAELYISNKQYDKALEIITDF-------SGIVLEKKTSEEGTSEENK 371
N E++++ ++KA+ + +F ++ E + + + +
Sbjct: 181 AVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLR 240
Query: 372 APE----------NVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDMG 421
A N+ C + ID+ + + L+P P
Sbjct: 241 ALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIE---LQPHFP-------------- 283
Query: 422 DLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAV-VWLRHAECLKAL-------GYME 473
D Y ++A A + G S + YN A+ + HA+ L L G +E
Sbjct: 284 DAYCNLANALKEKG---------SVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIE 334
Query: 474 RAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKAL 510
A Y K +++ P A +L+++ QQ G+ ++AL
Sbjct: 335 EAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEAL 371
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 16/205 (7%)
Query: 156 ANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPS 215
A + + +G + AI I P + + LA +++G + ++ A L P+
Sbjct: 256 ACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 315
Query: 216 DTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYR 275
+ LA + EQ NI++A+ Y KAL+ P +S+ +Q G + A+ Y+
Sbjct: 316 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 375
Query: 276 RILNLLSPSDGERFMQLARDMAKSYYEANDVTSAINI------IDEAFS-KHQGLVSM-E 327
+ +SP+ F +M + E DV A+ I+ AF+ H L S+ +
Sbjct: 376 EAIR-ISPT----FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHK 430
Query: 328 DVNIAAELYISNKQYDKALEIITDF 352
D E S Y AL++ DF
Sbjct: 431 DSGNIPEAIAS---YRTALKLKPDF 452
Score = 33.1 bits (74), Expect = 1.2
Identities = 26/107 (24%), Positives = 44/107 (41%), Gaps = 10/107 (9%)
Query: 741 HNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHMASQKYVLRRHALIVQGFSFL 800
H + +G F+ A +Q +R PD + L+ IH ++ H F
Sbjct: 19 HREYQAGDFEAAERHCMQLWRQEPDNT--GVLLLLSSIHFQCRRLDRSAH--------FS 68
Query: 801 NRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALELPPLVVEG 847
+ E++ NLG + G + AI +Y+ AL L P ++G
Sbjct: 69 TLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG 115
Score = 32.7 bits (73), Expect = 1.5
Identities = 76/388 (19%), Positives = 137/388 (35%), Gaps = 94/388 (24%)
Query: 197 GDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWE 256
GD E + + + P +T + L+ + + + ++ T A+K P
Sbjct: 25 GDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSN 84
Query: 257 RSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSYYEANDVTSAINIIDEA 316
++Y++ G + A++ YR L L + ID
Sbjct: 85 LGNVYKERGQLQEAIEHYRHALRLKP----------------------------DFIDGY 116
Query: 317 FSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKKTSEEGTSEENKA---- 372
+ LV+ D+ A + Y+S QY+ L + G +L+ G EE KA
Sbjct: 117 INLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKAL----GRLEEAKACYLK 172
Query: 373 -----PENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPEDMGDLYLDV 427
P G + ++ + + H L+P + D Y+++
Sbjct: 173 AIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP-----------NFLDAYINL 221
Query: 428 AEAFLDVGEYNSALPL-LSALVCSERY-----NLAVVWLRH------------------- 462
+ ++ A+ L AL S + NLA V+
Sbjct: 222 GNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPH 281
Query: 463 --------AECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKAL---- 510
A LK G + A + Y + L P H D+ +L+ ++++ G E+A+
Sbjct: 282 FPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYR 341
Query: 511 EALEPMYDPDTLAQDANAA---QQELKL 535
+ALE P+ A +N A QQ+ KL
Sbjct: 342 KALEVF--PEFAAAHSNLASVLQQQGKL 367
Score = 31.6 bits (70), Expect = 3.4
Identities = 32/142 (22%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 702 LWNIFNQVTMHSQDVRHHRFCLRLMLKNPENHALCVLNGHNAFVS-GSFKHALGQYVQAF 760
L N++ + + + H+R LRL + + +N A V+ G + A+ YV A
Sbjct: 85 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGY----INLAAALVAAGDMEGAVQAYVSAL 140
Query: 761 RTHPDEPLYSFCIGLTFIHMASQKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRG 820
+ +PD +C+ + +L+ + + + + + + ++ NLG
Sbjct: 141 QYNPD----LYCV------RSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCV 190
Query: 821 LHQLGLIHLAIHYYQKALELPP 842
+ G I LAIH+++KA+ L P
Sbjct: 191 FNAQGEIWLAIHHFEKAVTLDP 212
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/138 (23%), Positives = 66/138 (47%), Gaps = 1/138 (0%)
Query: 156 ANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPS 215
ANI+ +G EEA+ + + + P S LA + + QG ++++L A ++P+
Sbjct: 334 ANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPT 393
Query: 216 DTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYR 275
+ + + E +++ A+ CYT+A++ P +S+++ G+ A+ YR
Sbjct: 394 FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYR 453
Query: 276 RILNLLSPSDGERFMQLA 293
L L P + + LA
Sbjct: 454 TALK-LKPDFPDAYCNLA 470
Score = 48.9 bits (115), Expect = 2e-05
Identities = 48/202 (23%), Positives = 87/202 (43%), Gaps = 10/202 (4%)
Query: 157 NIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSD 216
N+ A G EEA ++ I P +S L ++ QG++ ++ A L+P+
Sbjct: 165 NLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNF 224
Query: 217 TEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRR 276
+ ++ L + E +A+ Y +AL P + + +Y + G +A+D YRR
Sbjct: 225 LDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRR 284
Query: 277 ILNLLSPSDGERFMQLARDMAK--SYYEAND-VTSAINIIDEAFSKHQGL--VSMEDVNI 331
+ L P + + LA + + S EA D +A+ + L + E NI
Sbjct: 285 AIE-LQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNI 343
Query: 332 AAELYISNKQYDKALEIITDFS 353
+ + Y KALE+ +F+
Sbjct: 344 EEAV----RLYRKALEVFPEFA 361
Score = 47.8 bits (112), Expect = 5e-05
Identities = 75/389 (19%), Positives = 145/389 (37%), Gaps = 75/389 (19%)
Query: 176 IRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQ 235
I+Q PL E +S L +Y+++G ++++++ A L P + ++ LA + +++
Sbjct: 82 IKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEG 141
Query: 236 AIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNL--------------- 280
A+ Y AL+Y P + +L + +G + A Y + +
Sbjct: 142 AVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVF 201
Query: 281 -------LSPSDGERFMQLARDMAKSYYEANDVTSAINIIDEAFSKHQGLVSME------ 327
L+ E+ + L + +Y +V I D A + + +S+
Sbjct: 202 NAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVV 261
Query: 328 DVNIAAELY------ISNKQYDKALEIITDFSGIV--LEKKTSEEGTSEENKAPENVTCT 379
N+A Y ++ Y +A+E+ F L E+G+ E + N
Sbjct: 262 HGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTA-- 319
Query: 380 IPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQ-NPEDMGDLYLDVAEAFLDVGEYN 438
L +C H + LN L EQ N E+ LY E F + +
Sbjct: 320 ------------LRLCPTH---ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAH 364
Query: 439 SALPLLSALVCSERYNLAVVWLRHAEC-----------------LKALGYMERAAESYGK 481
S L A V ++ L + + E LK + ++ A + Y +
Sbjct: 365 SNL----ASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTR 420
Query: 482 VVDLAPLHLDARISLSTLQQQLGQPEKAL 510
+ + P DA +L+++ + G +A+
Sbjct: 421 AIQINPAFADAHSNLASIHKDSGNIPEAI 449
Score = 45.4 bits (106), Expect = 2e-04
Identities = 77/400 (19%), Positives = 153/400 (38%), Gaps = 75/400 (18%)
Query: 148 ALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFEL 207
+ +GL A+ + G+ E A CM++ RQ P L+ I+ +++S F
Sbjct: 20 SFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFST 79
Query: 208 IAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDH 267
+A NP E + L + E+ +++AI Y AL+ +P + ++ GD
Sbjct: 80 LAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDM 139
Query: 268 KMAMDGYRRILNLLSPSDGERFMQLARDMAKSYYEANDVTSAINIIDEAFSKHQGLVSME 327
+ A+ Y L Q D+ + ++ A+ ++EA + + + +
Sbjct: 140 EGAVQAYVSAL------------QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ 187
Query: 328 D------------VNIAAELYISNKQYDKALEIITDF-------SGIVLEKKTSEEGTSE 368
N E++++ ++KA+ + +F ++ E + + +
Sbjct: 188 PNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAA 247
Query: 369 ENKAPE----------NVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTTLVEQNPE 418
+A N+ C + ID+ + + L+P P
Sbjct: 248 YLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIE---LQPHFP----------- 293
Query: 419 DMGDLYLDVAEAFLDVGEYNSALPLLSALVCSERYNLAV-VWLRHAECLKAL-------G 470
D Y ++A A + G S + YN A+ + HA+ L L G
Sbjct: 294 ---DAYCNLANALKEKG---------SVAEAEDCYNTALRLCPTHADSLNNLANIKREQG 341
Query: 471 YMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEKAL 510
+E A Y K +++ P A +L+++ QQ G+ ++AL
Sbjct: 342 NIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEAL 381
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/205 (24%), Positives = 88/205 (42%), Gaps = 16/205 (7%)
Query: 156 ANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPS 215
A + + +G + AI I P + + LA +++G + ++ A L P+
Sbjct: 266 ACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 325
Query: 216 DTEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYR 275
+ LA + EQ NI++A+ Y KAL+ P +S+ +Q G + A+ Y+
Sbjct: 326 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 385
Query: 276 RILNLLSPSDGERFMQLARDMAKSYYEANDVTSAINI------IDEAFS-KHQGLVSM-E 327
+ +SP+ F +M + E DV A+ I+ AF+ H L S+ +
Sbjct: 386 EAIR-ISPT----FADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHK 440
Query: 328 DVNIAAELYISNKQYDKALEIITDF 352
D E S Y AL++ DF
Sbjct: 441 DSGNIPEAIAS---YRTALKLKPDF 462
Score = 35.0 bits (79), Expect = 0.31
Identities = 79/404 (19%), Positives = 144/404 (35%), Gaps = 94/404 (23%)
Query: 181 LAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCY 240
L+++ + LA GD E + + + P +T + L+ + + + ++
Sbjct: 19 LSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFS 78
Query: 241 TKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSY 300
T A+K P ++Y++ G + A++ YR L L
Sbjct: 79 TLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKP------------------ 120
Query: 301 YEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAELYISNKQYDKALEIITDFSGIVLEKK 360
+ ID + LV+ D+ A + Y+S QY+ L + G +L+
Sbjct: 121 ----------DFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 170
Query: 361 TSEEGTSEENKA---------PENVTCTIPDGVPIDITVKLMVCLVHLNILEPLNPLLTT 411
G EE KA P G + ++ + + H L+P
Sbjct: 171 ----GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDP---- 222
Query: 412 LVEQNPEDMGDLYLDVAEAFLDVGEYNSALPL-LSALVCSERY-----NLAVVWLRH--- 462
+ D Y+++ + ++ A+ L AL S + NLA V+
Sbjct: 223 -------NFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLI 275
Query: 463 ------------------------AECLKALGYMERAAESYGKVVDLAPLHLDARISLST 498
A LK G + A + Y + L P H D+ +L+
Sbjct: 276 DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLAN 335
Query: 499 LQQQLGQPEKAL----EALEPMYDPDTLAQDANAA---QQELKL 535
++++ G E+A+ +ALE P+ A +N A QQ+ KL
Sbjct: 336 IKREQGNIEEAVRLYRKALEVF--PEFAAAHSNLASVLQQQGKL 377
Score = 33.1 bits (74), Expect = 1.2
Identities = 26/107 (24%), Positives = 44/107 (41%), Gaps = 10/107 (9%)
Query: 741 HNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHMASQKYVLRRHALIVQGFSFL 800
H + +G F+ A +Q +R PD + L+ IH ++ H F
Sbjct: 29 HREYQAGDFEAAERHCMQLWRQEPDNT--GVLLLLSSIHFQCRRLDRSAH--------FS 78
Query: 801 NRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALELPPLVVEG 847
+ E++ NLG + G + AI +Y+ AL L P ++G
Sbjct: 79 TLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDG 125
Score = 31.6 bits (70), Expect = 3.4
Identities = 32/142 (22%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 702 LWNIFNQVTMHSQDVRHHRFCLRLMLKNPENHALCVLNGHNAFVS-GSFKHALGQYVQAF 760
L N++ + + + H+R LRL + + +N A V+ G + A+ YV A
Sbjct: 95 LGNVYKERGQLQEAIEHYRHALRLKPDFIDGY----INLAAALVAAGDMEGAVQAYVSAL 150
Query: 761 RTHPDEPLYSFCIGLTFIHMASQKYVLRRHALIVQGFSFLNRYLSLRGPCQESFYNLGRG 820
+ +PD +C+ + +L+ + + + + + + ++ NLG
Sbjct: 151 QYNPD----LYCV------RSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCV 200
Query: 821 LHQLGLIHLAIHYYQKALELPP 842
+ G I LAIH+++KA+ L P
Sbjct: 201 FNAQGEIWLAIHHFEKAVTLDP 222
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 50.4 bits (119), Expect = 7e-06
Identities = 36/138 (26%), Positives = 67/138 (48%), Gaps = 13/138 (9%)
Query: 8 LIDYLEGK--ISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQ 65
L+D LE + +S EE E R EE + E++ +E+ + EE ++ +V K +
Sbjct: 2233 LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKK 2292
Query: 66 DKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLE 125
+K E + + V + ++ + E+ DEEEEEE EEE + ++
Sbjct: 2293 EKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE---------- 2342
Query: 126 MVLNRETKKMMKEKRPRS 143
+L +E + ++E+R +S
Sbjct: 2343 -ILKKEKQFKLQEQRRKS 2359
Score = 40.8 bits (94), Expect = 0.006
Identities = 35/150 (23%), Positives = 71/150 (47%), Gaps = 18/150 (12%)
Query: 8 LIDYLEGKISFEE---FERRREERKTREKKSLQEKGKLSAEENPDDSE------------ 52
L D EG I EE F +RR ++ K+ + K K S++ + +SE
Sbjct: 2176 LDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLD 2235
Query: 53 -VPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEE 111
+ ++S + ++++ E + VR+ + GE + E+EEEE++++++E++
Sbjct: 2236 ELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Query: 112 TPEQPTAGDVF--VLEMVLNRETKKMMKEK 139
E +VF E++ ET+ + E+
Sbjct: 2296 KEEVQEKEEVFEEKEEIMSEEETESLSDEE 2325
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Query: 20 EFERR--REERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDG 77
E +RR R + ++E+ + +E G + S+ ++ N + ++DV E E +
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217
Query: 78 VRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEE 111
+ +V GE E++EEEEEEEEEEEEEEE
Sbjct: 218 DAEEDEEVDED--GEEEEEEEEEEEEEEEEEEEE 249
Score = 48.1 bits (113), Expect = 4e-05
Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 9/94 (9%)
Query: 26 EERKTREKKSLQEKGKLSAEENPDDSEVPSSSGI----NSTKSQDKDVNEGETSDGVRKS 81
+ R +R +S +E+ +++EE D E SS N+T+++++ V E D +
Sbjct: 160 DRRASRSSQSSKEE--VNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED---EE 214
Query: 82 VHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQ 115
V + +ED EEEEEEEEEEEEEEE E+
Sbjct: 215 VEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248
Score = 44.7 bits (104), Expect = 4e-04
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 25 REERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHK 84
+EE + E S E G + + ++ G+ +D++V E D + V +
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED---EEVDE 227
Query: 85 VFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
E E++EEEEEEEEEE E++E ++ D
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGND 263
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/94 (34%), Positives = 51/94 (54%), Gaps = 4/94 (4%)
Query: 20 EFERR--REERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDG 77
E +RR R + ++E+ + +E G + S+ ++ N + ++DV E E +
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217
Query: 78 VRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEE 111
+ +V GE E++EEEEEEEEEEEEEEE
Sbjct: 218 DAEEDEEVDED--GEEEEEEEEEEEEEEEEEEEE 249
Score = 48.1 bits (113), Expect = 4e-05
Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 9/94 (9%)
Query: 26 EERKTREKKSLQEKGKLSAEENPDDSEVPSSSGI----NSTKSQDKDVNEGETSDGVRKS 81
+ R +R +S +E+ +++EE D E SS N+T+++++ V E D +
Sbjct: 160 DRRASRSSQSSKEE--VNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEED---EE 214
Query: 82 VHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQ 115
V + +ED EEEEEEEEEEEEEEE E+
Sbjct: 215 VEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248
Score = 44.7 bits (104), Expect = 4e-04
Identities = 27/96 (28%), Positives = 45/96 (46%), Gaps = 3/96 (3%)
Query: 25 REERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHK 84
+EE + E S E G + + ++ G+ +D++V E D + V +
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED---EEVDE 227
Query: 85 VFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
E E++EEEEEEEEEE E++E ++ D
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGND 263
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 48.1 bits (113), Expect = 4e-05
Identities = 39/190 (20%), Positives = 83/190 (43%), Gaps = 7/190 (3%)
Query: 128 LNRETKKM-MKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPF 186
L R+T + M +R P+ R L N+ ++ ++EEAI + + I+ P + +
Sbjct: 418 LTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAY 477
Query: 187 STLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKALKY 246
S+LA + +Q +++ + P ++ ++ ++A+ Y +A+K
Sbjct: 478 SSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKL 537
Query: 247 EPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSYYEANDV 306
P++ + LY +G++ MA + Y+R L + + ++ + YY
Sbjct: 538 SPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKA------EILSPLGALYYNTGRY 591
Query: 307 TSAINIIDEA 316
A+ I EA
Sbjct: 592 EEALQIYQEA 601
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 20/180 (11%)
Query: 184 EPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSLEQDNIKQAIFCYTKA 243
E S L +Y + G E++LQ AA L PS E + LA++ K+A
Sbjct: 576 EILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHI 635
Query: 244 LKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRRILNLLSPSDGERFMQLARDMAKSYYEA 303
+ E + S++Y + +H A+D + L L P D + +L ++
Sbjct: 636 VSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQ-LKPKDPKVISEL-------FFTK 687
Query: 304 NDVTSAINIIDEAFSKHQGLVSMED------VNIAAELYISNK------QYDKALEIITD 351
+ N++D+AF ++ V + +N+ +I K Y++AL+++ D
Sbjct: 688 GNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPD 747
Score = 35.0 bits (79), Expect = 0.31
Identities = 56/271 (20%), Positives = 102/271 (37%), Gaps = 20/271 (7%)
Query: 26 EERKTREKKSLQEKGKLSAEENPDDSEVPSSSGIN--STKSQDKDVNEGETSDGVRKSVH 83
E+ + +E + + + G + PD S++ ++ G+ T +K V + + + S H
Sbjct: 486 EQERFKEAEEIYQTG---IKNCPDSSDLHNNYGVFLVDTGLPEKAVAHYQQAIKLSPSHH 542
Query: 84 KVFASM------LGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMK 137
++ LGEN EE + + + E A E ++ +
Sbjct: 543 VAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSPLGA---LYYNTGRYEEALQIYQ 599
Query: 138 EKRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQG 197
E R LR + A + G+ +EA M I+ + E + L+ IY Q
Sbjct: 600 EAAALQPSQRELR--LALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQE 657
Query: 198 DMEKSLQFELIAAHLNPSD----TEEWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRY 253
+ +K+L A L P D +E + EQ+ + +A Y A++ P +
Sbjct: 658 NHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQA 717
Query: 254 LWERSSLYEQMGDHKMAMDGYRRILNLLSPS 284
+ G + A Y R L L+ S
Sbjct: 718 WMNMGGIQHIKGKYVSARAYYERALQLVPDS 748
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 47.8 bits (112), Expect = 5e-05
Identities = 22/29 (75%), Positives = 24/29 (82%)
Query: 91 GENEDDEEEEEEEEEEEEEEETPEQPTAG 119
G E++EEEEEEEEEEEEEEE EQP AG
Sbjct: 124 GGEEEEEEEEEEEEEEEEEEEEEEQPRAG 152
Score = 36.6 bits (83), Expect = 0.11
Identities = 16/29 (55%), Positives = 21/29 (72%)
Query: 92 ENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
E E++EEEEEEEEEEEE+ Q + G+
Sbjct: 131 EEEEEEEEEEEEEEEEEQPRAGPQGSGGN 159
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 47.8 bits (112), Expect = 5e-05
Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 7/101 (6%)
Query: 13 EGKISFEEFERRREE--RKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVN 70
EG+ E ER +EE RK E+ +EKG+ ++ + E + G K + +V
Sbjct: 758 EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEE--ETEGRGEEKEEGGEVE 815
Query: 71 EGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEE 111
GE +G + + GE E++E E EEEE E EEEE
Sbjct: 816 GGEVEEGKGEREEE---EEEGEGEEEEGEGEEEEGEGEEEE 853
Score = 45.1 bits (105), Expect = 3e-04
Identities = 35/114 (30%), Positives = 51/114 (44%), Gaps = 10/114 (8%)
Query: 12 LEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNE 71
+EG+ EE ER++EER +E EKG+ ++ + E G + + + E
Sbjct: 764 VEGEREKEEGERKKEERAGKE-----EKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE 818
Query: 72 GETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEE-----EEEEETPEQPTAGD 120
E G R+ + E E +EEE E EEEE EEE E E G+
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872
Score = 42.4 bits (98), Expect = 0.002
Identities = 40/142 (28%), Positives = 59/142 (41%), Gaps = 6/142 (4%)
Query: 26 EERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKV 85
EER+ EK +KG+ E P + E + K ++ + E G +K ++
Sbjct: 672 EEREKGEK----DKGR-GEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQE 726
Query: 86 FASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKL 145
GE E E EEEE + EEEEE+ E G+ +E +E + KE+R +
Sbjct: 727 MEEG-GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785
Query: 146 PRALRGLMGEANIRFARGEREE 167
G GE G EE
Sbjct: 786 KGEEEGDQGEGEEEETEGRGEE 807
Score = 42.0 bits (97), Expect = 0.003
Identities = 29/103 (28%), Positives = 44/103 (42%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
EG+ EE E E + E + + +G+ EE + E + + ++ EG
Sbjct: 952 EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011
Query: 73 ETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQ 115
E + V GE E +EEE EEE EE E+E E+
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEE 1054
Score = 40.4 bits (93), Expect = 0.007
Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 8/111 (7%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSA-----EENPDDSEVPSSSGINSTKSQDKDVN-EG 72
E+ ++ RE+ +E+ E+G EE D E G + + ++V E
Sbjct: 709 EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER 768
Query: 73 ETSDGVRKSVHKVFASMLGENEDD--EEEEEEEEEEEEEEETPEQPTAGDV 121
E +G RK + GE E D E EEEE E EE+E + G+V
Sbjct: 769 EKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEV 819
Score = 40.4 bits (93), Expect = 0.007
Identities = 31/107 (28%), Positives = 45/107 (42%), Gaps = 15/107 (14%)
Query: 14 GKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGE 73
G++ E E + ER+ E++ E+ + EE + E G K EGE
Sbjct: 812 GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEG--------KGEEEGE 863
Query: 74 TSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
+G + GE E +EEE E E EEE E E E+ G+
Sbjct: 864 EGEGEEEGEE-------GEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903
Score = 39.7 bits (91), Expect = 0.013
Identities = 31/105 (29%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
EG+ EE E EE + E + +E+G+ EE + E G + + + EG
Sbjct: 969 EGEGEGEEGEGEGEEEEG-EGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG 1027
Query: 73 ETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPT 117
E +G + E E + EE EEEEEEE Q T
Sbjct: 1028 EEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQET 1072
Score = 39.3 bits (90), Expect = 0.016
Identities = 44/155 (28%), Positives = 58/155 (37%), Gaps = 7/155 (4%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
EGK EE E E + E + E G+ EE + E G + + + E
Sbjct: 918 EGK-GEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEE 976
Query: 73 ETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRET 132
+G + GE E +EE E EEE E E EE E G+V E E
Sbjct: 977 GEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEE 1036
Query: 133 KKMMKEKRPRSKLPRALRGLMGEANIRFARGEREE 167
++ +E R K GE N R E EE
Sbjct: 1037 EEGEEEGEEREKEGE------GEENRRNREEEEEE 1065
Score = 38.5 bits (88), Expect = 0.028
Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 2/99 (2%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSS--SGINSTKSQDKDVNEGETSD 76
EE +R EE K E K E ++ E ++ E +G ++ D EGE +
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEE 800
Query: 77 GVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQ 115
+ K + E +E + E EEEEEE E E+
Sbjct: 801 TEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Score = 38.1 bits (87), Expect = 0.036
Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 9/117 (7%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVN-- 70
EG+ EE E E + E + +E+G+ EE ++ E + +D +
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGE 949
Query: 71 ------EGETSDGVRKSVHKVFAS-MLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
EGE +G + + GE E +EEE E E EEEE EE E+ G+
Sbjct: 950 EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006
Score = 38.1 bits (87), Expect = 0.036
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
EG+ EE E EE + E+ + +G+ EE + E + ++ EG
Sbjct: 978 EGEGEEEEGEGEGEEEEGEEEGEEEGEGE---EEGEGEGEEEEEGEVEGEVEGEEGEGEG 1034
Query: 73 ETSDGVRKSVHKVFASMLGENEDDEEEEEEEE---EEEEEEETPEQ 115
E +G + + EN + EEEEEEE +E EEE Q
Sbjct: 1035 EEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ 1080
Score = 37.7 bits (86), Expect = 0.048
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 7/108 (6%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
EG+ EE E E + E + +E+G+ EE + + + K EG
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEG-------EEEEGEGKGEEEG 925
Query: 73 ETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
E +G + GE E +EEE E E EEEE E E+ G+
Sbjct: 926 EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Score = 31.2 bits (69), Expect = 4.5
Identities = 27/110 (24%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
Query: 7 ELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKS-Q 65
EL + E K E + ++E + +K+ QE + EE+ + E K +
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754
Query: 66 DKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQ 115
K+ EGE +G R+ + E + ++EE +EE+ EE +Q
Sbjct: 755 GKEEGEGEEVEGERE-----------KEEGERKKEERAGKEEKGEEEGDQ 793
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 47.4 bits (111), Expect = 6e-05
Identities = 34/115 (29%), Positives = 53/115 (46%), Gaps = 13/115 (11%)
Query: 33 KKSLQEKGKLSAEENPDDSE----VPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFAS 88
K LQE KL E + + + G + +++++ + DG K
Sbjct: 598 KAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEK-------- 649
Query: 89 MLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRS 143
+ + E +EE EEEEE+EEEEEE Q TA + E + ++ K+M KE S
Sbjct: 650 -VEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKENNDGS 703
Score = 41.6 bits (96), Expect = 0.003
Identities = 40/163 (24%), Positives = 73/163 (44%), Gaps = 23/163 (14%)
Query: 7 ELIDYLEGKISFEEFERRREERKTREKKSLQEKGKL-SAEENPDDSEVPSSSGINSTKSQ 65
EL+D GK F + RK+ +K++++E L S + D+ P+SS +N Q
Sbjct: 910 ELLDLCTGK--FTSQAEKHLPRKSDKKENMEELLNLCSGKFTSQDASTPASSELNK---Q 964
Query: 66 DKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEE----------EEEEEETPEQ 115
+K+ + G+ + + A G D+EEE+EEEE E + + E
Sbjct: 965 EKESSMGDPME-------EALALCSGSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDEH 1017
Query: 116 PTAGDVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANI 158
+G+ LE + + ++++K + R + L EA +
Sbjct: 1018 SDSGNDLALEDHEDDDEEELLKRSEKLKRQMRLRKYLEDEAEV 1060
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 47.0 bits (110), Expect = 8e-05
Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 15/135 (11%)
Query: 25 REERKTREKKSLQEKGKLSAEENPDDSEVPS----SSGINSTKSQDKDVNEGETSDGVRK 80
+E++K ++KKS +++ K EE D+++ P SG + K +D+D + E RK
Sbjct: 796 KEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDK---RK 852
Query: 81 SVHKVFASMLGENEDDE------EEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKK 134
K +N DE EE E+EE++ +EEE ++ D + R +K
Sbjct: 853 DDSKDDDETEEDNNQDEYDPMEAEEAEDEEDDRDEEEMTKRDDKRD--INRYCKERPSKD 910
Query: 135 MMKEKRPRSKLPRAL 149
KEK + R L
Sbjct: 911 KEKEKTQMITINRDL 925
Score = 39.7 bits (91), Expect = 0.013
Identities = 29/138 (21%), Positives = 62/138 (44%), Gaps = 9/138 (6%)
Query: 3 GFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINST 62
G+ +L++ L+G+ + E+ EE+ E K + S + P + +N
Sbjct: 592 GYKQQLVEKLQGERKEADGEQDEEEKDDGEAKEISTPTHWSKLD-------PKTMKVNDL 644
Query: 63 KSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVF 122
+ + + + +S G++ + L E EE++E E+ E+EE+E ++ + D
Sbjct: 645 RKELE--SRALSSKGLKSQLIARLTKQLKVEEQKEEQKELEKSEKEEDEDDDRKSEDDKE 702
Query: 123 VLEMVLNRETKKMMKEKR 140
E E ++ +E+R
Sbjct: 703 EEERKRQEEIERQRRERR 720
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 47.0 bits (110), Expect = 8e-05
Identities = 35/109 (32%), Positives = 54/109 (49%), Gaps = 9/109 (8%)
Query: 12 LEGKISFEEFERRREERKTREKKSLQEKGKLS--AEENPDDSEVPSSSGINS---TKSQD 66
L G + F+ +R+E + S +++ + S AEE+ DD E +G TK
Sbjct: 884 LRGALRLPSFKVKRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPK 943
Query: 67 KDVNEGETSDGVRKSV----HKVFASMLGENEDDEEEEEEEEEEEEEEE 111
+D G+T RKS AS +E DEE++EE+EE+E+ EE
Sbjct: 944 RDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREE 992
Score = 33.9 bits (76), Expect = 0.69
Identities = 27/126 (21%), Positives = 53/126 (42%), Gaps = 35/126 (27%)
Query: 22 ERRREERKTREKKSLQEKGKLSAEENP----------DDSEVPSSSGINSTKSQDKDVNE 71
ER + + K R+ +L +G+ +++E+ D+ + +++TK ++ +V++
Sbjct: 947 ERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTK-KETEVSD 1005
Query: 72 GETSDGVRKSVHKVFASMLGENEDDEEEE------------------------EEEEEEE 107
GE + S ++A GEN+ + E E E+E
Sbjct: 1006 GEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE 1065
Query: 108 EEEETP 113
EEEE P
Sbjct: 1066 EEEERP 1071
Score = 32.0 bits (71), Expect = 2.6
Identities = 14/31 (45%), Positives = 21/31 (67%)
Query: 90 LGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
L + ++ EEE EEE EEEEEE+ + ++ D
Sbjct: 1354 LQQQREEGEEEGEEEGEEEEEESSDSSSSSD 1384
Score = 30.8 bits (68), Expect = 5.8
Identities = 25/95 (26%), Positives = 35/95 (36%), Gaps = 4/95 (4%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGV 78
EE E R E T +K++ G E+ DS S +S D + +S
Sbjct: 985 EEDEDREEAVDTTKKETEVSDG----EDEESDSSSKCSLYADSDGENDSTSDSESSSSSS 1040
Query: 79 RKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETP 113
S +S + E E+EEEEE P
Sbjct: 1041 SSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALP 1075
Score = 30.8 bits (68), Expect = 5.8
Identities = 18/55 (32%), Positives = 24/55 (43%)
Query: 94 EDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKLPRA 148
E +EE EEE EEEEEE + G+ + L ++ P PRA
Sbjct: 1360 EGEEEGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPPRA 1414
Score = 30.4 bits (67), Expect = 7.6
Identities = 25/100 (25%), Positives = 36/100 (36%), Gaps = 4/100 (4%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGV 78
EE + EE + RE+ K + + D+ S S + D D TSD
Sbjct: 978 EEDDEEDEEDEDREEAVDTTKKETEVSDGEDEE---SDSSSKCSLYADSDGENDSTSDSE 1034
Query: 79 RKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTA 118
S +S + E E+EEE E+P A
Sbjct: 1035 SSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEE-EERPAA 1073
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 47.0 bits (110), Expect = 8e-05
Identities = 32/99 (32%), Positives = 49/99 (49%), Gaps = 16/99 (16%)
Query: 69 VNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD-------- 120
V+E SD + V + + E E++EEEEEEEEEEEEEEE E +G+
Sbjct: 279 VDERVDSDS-KSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSS 337
Query: 121 -------VFVLEMVLNRETKKMMKEKRPRSKLPRALRGL 152
+ + + ++K K + PR+K PR + G+
Sbjct: 338 GRRKAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVNGV 376
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 46.6 bits (109), Expect = 1e-04
Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 18/116 (15%)
Query: 73 ETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQP---------------- 116
E D KS + L E E++EEEEEEEEEEEEEEE E+
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRR 340
Query: 117 TAGDVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAILMC 172
A + + + ++K K + PR+K PR + +++ RG E + C
Sbjct: 341 KAKKKWRKDSPWVKPSRKRRKREPPRAKEPRGVSN--DTSSLETERGFEELPLCSC 394
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 46.6 bits (109), Expect = 1e-04
Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 26/165 (15%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
+ + +F E RREER+ +K LQE L ++ D + +S + S + Q+ D E
Sbjct: 85 DDEAAFLERLARREERR---QKRLQEA--LERQKEFDPTITDASLSLPSRRMQN-DTAEN 138
Query: 73 ETSDGVRKSVHKVFASMLGENED-------------DEEEEEEEEEEEEEEETPEQPTAG 119
ET++ KS + + E E +E ++E++E+EEEEEE P++ + G
Sbjct: 139 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 198
Query: 120 DVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGE 164
+ + + +K+ K+K P+ ++ + G ++ GE
Sbjct: 199 ENQI-------KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 236
>gi|4826657 caldesmon 1 isoform 2 [Homo sapiens]
Length = 538
Score = 46.6 bits (109), Expect = 1e-04
Identities = 42/165 (25%), Positives = 79/165 (47%), Gaps = 26/165 (15%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
+ + +F E RREER+ +K LQE L ++ D + +S + S + Q+ D E
Sbjct: 91 DDEAAFLERLARREERR---QKRLQEA--LERQKEFDPTITDASLSLPSRRMQN-DTAEN 144
Query: 73 ETSDGVRKSVHKVFASMLGENED-------------DEEEEEEEEEEEEEEETPEQPTAG 119
ET++ KS + + E E +E ++E++E+EEEEEE P++ + G
Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 204
Query: 120 DVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGE 164
+ + + +K+ K+K P+ ++ + G ++ GE
Sbjct: 205 ENQI-------KDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 242
Score = 32.3 bits (72), Expect = 2.0
Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 20/132 (15%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGV 78
++FERRRE R+ + ++ E +++ + N DD E + + + + E S
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEES--- 58
Query: 79 RKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTA----GDVFVLEMVLNRETK- 133
LG+ D E + +EE +T T + LE + RE +
Sbjct: 59 -----------LGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERR 107
Query: 134 -KMMKEKRPRSK 144
K ++E R K
Sbjct: 108 QKRLQEALERQK 119
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 46.6 bits (109), Expect = 1e-04
Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 8/132 (6%)
Query: 16 ISFEEFERRREERKTREKKSLQEKGK---LSAEENPDDSEVPSSSG---INSTKSQDKDV 69
+S EE E +E + E+ S EK + LS N S S ++S +S+
Sbjct: 997 VSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTG 1056
Query: 70 NEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLN 129
G+ + ++S + + E++EEEEEEEE+EEEEEE E+ ++ L
Sbjct: 1057 ERGQLLELSKESSEEEEEEE--DEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLT 1114
Query: 130 RETKKMMKEKRP 141
+ +K KRP
Sbjct: 1115 KPQSVAIKRKRP 1126
Score = 44.7 bits (104), Expect = 4e-04
Identities = 39/167 (23%), Positives = 69/167 (41%), Gaps = 30/167 (17%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGV 78
EE E EE + E++ +E+G + E++PD + KSQ+K+ E T
Sbjct: 1353 EEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGA-----------KSQEKEEPEISTE--- 1398
Query: 79 RKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKE 138
K ++ L ++E++EEE+EE E+ + E + + E+ ++ KE
Sbjct: 1399 -----KEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDS-----------HMESAEVEKE 1442
Query: 139 KRPRSKLPRALRGLMGEANIRFARGEREEAILMCMEIIRQAPLAYEP 185
+ PR L ++ G +LM + A EP
Sbjct: 1443 ELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEP 1489
Score = 42.0 bits (97), Expect = 0.003
Identities = 36/129 (27%), Positives = 54/129 (41%), Gaps = 34/129 (26%)
Query: 24 RREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDG---VRK 80
+R K R+ K + KL+ P E P T + K+ +EG+TS + +
Sbjct: 1253 KRGLSKWRQNKERKTGFKLNLYTPP---ETPMEPDEQVTVEEQKETSEGKTSPSPIRIEE 1309
Query: 81 SVHKVFASMLGENE----------------------------DDEEEEEEEEEEEEEEET 112
V + ++L + E ++EEEEEEEEEEEEEEE
Sbjct: 1310 EVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEG 1369
Query: 113 PEQPTAGDV 121
E+ G+V
Sbjct: 1370 EEEEGGGNV 1378
Score = 38.9 bits (89), Expect = 0.021
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 21/114 (18%)
Query: 23 RRREERKTREKKSL--------QEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG-- 72
R+ +ERKT K +L + +++ EE + SE +S + + K+ E
Sbjct: 1260 RQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALL 1319
Query: 73 --------ETSDGVRKSV---HKVFASMLGENEDDEEEEEEEEEEEEEEETPEQ 115
ET V + K ++ E++EEEEEEEEEEEEEE E+
Sbjct: 1320 PQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEE 1373
>gi|20336305 B-cell CLL/lymphoma 11A isoform 1 [Homo sapiens]
Length = 835
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 6/74 (8%)
Query: 53 VPSSSGINSTKSQDKDVNE--GETSDGVRKSVHKVFA----SMLGENEDDEEEEEEEEEE 106
V S G+++ S + ++ G S ++ V K + +++ EN D+EEEE++EEEE
Sbjct: 436 VKSDDGLSTASSPEPGTSDLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEE 495
Query: 107 EEEEETPEQPTAGD 120
EEEEE E+ T +
Sbjct: 496 EEEEEEEEELTESE 509
>gi|20336307 B-cell CLL/lymphoma 11A isoform 2 [Homo sapiens]
Length = 773
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/74 (35%), Positives = 43/74 (58%), Gaps = 6/74 (8%)
Query: 53 VPSSSGINSTKSQDKDVNE--GETSDGVRKSVHKVFA----SMLGENEDDEEEEEEEEEE 106
V S G+++ S + ++ G S ++ V K + +++ EN D+EEEE++EEEE
Sbjct: 436 VKSDDGLSTASSPEPGTSDLVGSASSALKSVVAKFKSENDPNLIPENGDEEEEEDDEEEE 495
Query: 107 EEEEETPEQPTAGD 120
EEEEE E+ T +
Sbjct: 496 EEEEEEEEELTESE 509
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Query: 22 ERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKS 81
E R+EE + + + E+G+ EE+ SEVP++S +S+ S + + E E V +
Sbjct: 1221 EERKEEEEMQAEAEEAEEGE---EEDAASSEVPAASPADSSNSPETETKEPE----VEEE 1273
Query: 82 VHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
K S ++E++E EE E EEEE+ + D
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQND 1312
Score = 38.1 bits (87), Expect = 0.036
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 6 PELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAE--ENPD-DSEVPSSSGINST 62
PE+ + E EE + EE++ E+ +E+ +AE +N D D++ + ST
Sbjct: 1268 PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLEST 1327
Query: 63 KSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVF 122
K K++ E T + V++ V S L N E+ +++EE E + EQP+
Sbjct: 1328 KK--KELEEQPTREDVKEEPG-VQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSV 1384
Query: 123 VLEMVLNRE--------TKKMMKEKRPRSKLPRA 148
V E + E TK+ + E + ++P +
Sbjct: 1385 VSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHS 1418
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Query: 22 ERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKS 81
E R+EE + + + E+G+ EE+ SEVP++S +S+ S + + E E V +
Sbjct: 1221 EERKEEEEMQAEAEEAEEGE---EEDAASSEVPAASPADSSNSPETETKEPE----VEEE 1273
Query: 82 VHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
K S ++E++E EE E EEEE+ + D
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQND 1312
Score = 38.1 bits (87), Expect = 0.036
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 6 PELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAE--ENPD-DSEVPSSSGINST 62
PE+ + E EE + EE++ E+ +E+ +AE +N D D++ + ST
Sbjct: 1268 PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLEST 1327
Query: 63 KSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVF 122
K K++ E T + V++ V S L N E+ +++EE E + EQP+
Sbjct: 1328 KK--KELEEQPTREDVKEEPG-VQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSV 1384
Query: 123 VLEMVLNRE--------TKKMMKEKRPRSKLPRA 148
V E + E TK+ + E + ++P +
Sbjct: 1385 VSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHS 1418
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/99 (30%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Query: 22 ERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKS 81
E R+EE + + + E+G+ EE+ SEVP++S +S+ S + + E E V +
Sbjct: 1221 EERKEEEEMQAEAEEAEEGE---EEDAASSEVPAASPADSSNSPETETKEPE----VEEE 1273
Query: 82 VHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
K S ++E++E EE E EEEE+ + D
Sbjct: 1274 EEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQND 1312
Score = 38.1 bits (87), Expect = 0.036
Identities = 39/154 (25%), Positives = 70/154 (45%), Gaps = 14/154 (9%)
Query: 6 PELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSAE--ENPD-DSEVPSSSGINST 62
PE+ + E EE + EE++ E+ +E+ +AE +N D D++ + ST
Sbjct: 1268 PEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLEST 1327
Query: 63 KSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVF 122
K K++ E T + V++ V S L N E+ +++EE E + EQP+
Sbjct: 1328 KK--KELEEQPTREDVKEEPG-VQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSV 1384
Query: 123 VLEMVLNRE--------TKKMMKEKRPRSKLPRA 148
V E + E TK+ + E + ++P +
Sbjct: 1385 VSEQMAGSEDDHEEDSHTKEELIELKEEEEIPHS 1418
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 45.8 bits (107), Expect = 2e-04
Identities = 50/184 (27%), Positives = 77/184 (41%), Gaps = 14/184 (7%)
Query: 55 SSSGINSTKSQDKDVNEGE---TSDGVRKSVHKVFASMLGENEDDEEE-EEEEEEEEEEE 110
+SS S++ +D EGE DG S A E E++EEE EEEEEEEEEEE
Sbjct: 424 ASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEEEEAEEEEEEEEEEE 483
Query: 111 ETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRFARGEREEAIL 170
E E +F E L+ E E RP + P A G + ++ + + L
Sbjct: 484 EEEEDEGCKGLFPSE--LDEEL-----EDRPHEE-PGAAAGSSSKKDLALSNQSISNSPL 535
Query: 171 M--CMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTEEWVRLAEMSL 228
M ++ + + + S + + D + L F N ++ + A+ S
Sbjct: 536 MPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGVRANVAEGGRRLDFADESA 595
Query: 229 EQDN 232
+DN
Sbjct: 596 NKDN 599
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 15/82 (18%)
Query: 35 SLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENE 94
++ E +S E ++ E +SS S+ S ++ E + E E
Sbjct: 7 NMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDE---------------EEE 51
Query: 95 DDEEEEEEEEEEEEEEETPEQP 116
++EEEEEEEEEEEEEEE P P
Sbjct: 52 EEEEEEEEEEEEEEEEEAPPPP 73
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/66 (39%), Positives = 34/66 (51%)
Query: 65 QDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVL 124
++++ E TS S V E +++EEEEEEEEEEEEEEE E+ V
Sbjct: 18 EEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVS 77
Query: 125 EMVLNR 130
E L R
Sbjct: 78 EEHLRR 83
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 45.4 bits (106), Expect = 2e-04
Identities = 36/152 (23%), Positives = 71/152 (46%), Gaps = 20/152 (13%)
Query: 13 EGKISFEEFERRREE----RKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKD 68
EG+ EE E EE + E++ ++E+G + ++E ++ E SS G+ + + +
Sbjct: 421 EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEA-EDWAQG 479
Query: 69 VNEGETSDGVRKSVHKVFASML------------GENEDDEEEEEEEEEEEEEEETPEQ- 115
V E S G + + L E EDDEEE++E+E+++++EE ++
Sbjct: 480 VVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
Query: 116 --PTAGDVFVLEMVLNRETKKMMKEKRPRSKL 145
P+ G+ ++ R + R +S +
Sbjct: 540 PVPSFGEAMAYFAMVKRYLTSFPIDDRVQSHI 571
Score = 38.5 bits (88), Expect = 0.028
Identities = 20/32 (62%), Positives = 23/32 (71%), Gaps = 3/32 (9%)
Query: 91 GENEDDEEEEEEEEE---EEEEEETPEQPTAG 119
GE E++EEEEEEEEE EEEEEE E+ G
Sbjct: 405 GEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEG 436
Score = 37.7 bits (86), Expect = 0.048
Identities = 30/130 (23%), Positives = 48/130 (36%), Gaps = 28/130 (21%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSD-- 76
EE E EE + E + +E+G+ EE + E+ + D D E E +
Sbjct: 408 EEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESS 467
Query: 77 -----------------------GVRKSVHKVFASMLGENED---DEEEEEEEEEEEEEE 110
G ++ L ED D EEE++EEE++E+E
Sbjct: 468 SEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDE 527
Query: 111 ETPEQPTAGD 120
+ + GD
Sbjct: 528 DDDDDEEDGD 537
Score = 37.4 bits (85), Expect = 0.062
Identities = 17/31 (54%), Positives = 22/31 (70%)
Query: 85 VFASMLGENEDDEEEEEEEEEEEEEEETPEQ 115
+ S+ E E++EEEEEEEEEEE E E E+
Sbjct: 397 ITTSLKSEGEEEEEEEEEEEEEEGEGEEEEE 427
Score = 37.4 bits (85), Expect = 0.062
Identities = 17/29 (58%), Positives = 22/29 (75%)
Query: 92 ENEDDEEEEEEEEEEEEEEETPEQPTAGD 120
++E +EEEEEEEEEEEEE E E+ G+
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGE 430
Score = 36.2 bits (82), Expect = 0.14
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 16/89 (17%)
Query: 35 SLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENE 94
SL+ +G+ EE ++ E G + ++ + E E +G LGE E
Sbjct: 400 SLKSEGE---EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEE----------LGEEE 446
Query: 95 DDEEE---EEEEEEEEEEEETPEQPTAGD 120
+ EEE + +EEEEE+EE + E A D
Sbjct: 447 EVEEEGDVDSDEEEEEDEESSSEGLEAED 475
Score = 34.7 bits (78), Expect = 0.40
Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 15/67 (22%)
Query: 54 PSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETP 113
P+++ S KS+ ++ E E + E E+ E EEEEEE EEEEEE
Sbjct: 393 PNATITTSLKSEGEEEEEEEEEE---------------EEEEGEGEEEEEEGEEEEEEGG 437
Query: 114 EQPTAGD 120
E G+
Sbjct: 438 EGEELGE 444
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 45.4 bits (106), Expect = 2e-04
Identities = 33/126 (26%), Positives = 56/126 (44%), Gaps = 8/126 (6%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGV 78
E+ + EE++ R+KK +E+G+ S E + + + + K+ E E
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERE--- 159
Query: 79 RKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKE 138
RK K +GE E++ +E+E +E ++ E E+ E RE KK K+
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKE-----RERKERRERKKERKK 214
Query: 139 KRPRSK 144
K R K
Sbjct: 215 KEERKK 220
Score = 41.2 bits (95), Expect = 0.004
Identities = 29/126 (23%), Positives = 55/126 (43%), Gaps = 24/126 (19%)
Query: 19 EEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEGETSDGV 78
E+ +R RE+ + RE+ ++KG+ EE + ++K+ EGE +
Sbjct: 67 EKRKREREKERKRERGKKEKKGERKKEERE-----------RKKRRREKENKEGEEKEKR 115
Query: 79 RKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKE 138
+K K E ++ E +EE + EE +E E ++ RE ++ KE
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKE-------------EREKERERKE 162
Query: 139 KRPRSK 144
++ R +
Sbjct: 163 RKKRER 168
Score = 38.5 bits (88), Expect = 0.028
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 20/135 (14%)
Query: 13 EGKISFEEFERRREERKTREKKSLQEKGKLSAEENPDDSEVPSSSGINSTKSQDKDVNEG 72
EGK + ER+REERK RE+K +E+ + E G + ++K+ E
Sbjct: 129 EGKERERKEERKREERKERERK--KEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 73 ETSDGVRKSVHKVFASMLGENEDDEEEEEEEEEEEEEEETPEQPTAGDVFVLEMVLNRET 132
+ + RK K E E E E ++E +++EE E+ +R+T
Sbjct: 187 KKRERNRKERKK-------ERERKERRERKKERKKKEERKKERQK-----------DRQT 228
Query: 133 KKMMKEKRPRSKLPR 147
KE+ R + R
Sbjct: 229 NWREKERGKRERKER 243
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,003,165
Number of Sequences: 37866
Number of extensions: 1481915
Number of successful extensions: 34549
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 573
Number of HSP's successfully gapped in prelim test: 482
Number of HSP's that attempted gapping in prelim test: 15365
Number of HSP's gapped (non-prelim): 7775
length of query: 886
length of database: 18,247,518
effective HSP length: 111
effective length of query: 775
effective length of database: 14,044,392
effective search space: 10884403800
effective search space used: 10884403800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.