Search of human proteins with 67089160

Search of human proteins with 67089160

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
sapiens]
         (781 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|67089160 promyelocytic leukemia protein isoform 11 [Homo sapi...  1593   0.0  
gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]  1570   0.0  
gi|15451779 promyelocytic leukemia protein isoform 10 [Homo sapi...  1065   0.0  
gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]   1042   0.0  
gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]  1042   0.0  
gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]  1041   0.0  
gi|109637788 promyelocytic leukemia protein isoform 5 [Homo sapi...  1006   0.0  
gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]   857   0.0  
gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]   857   0.0  
gi|239752618 PREDICTED: similar to promyelocytic leukemia protei...   211   2e-54
gi|30794216 tripartite motif-containing 56 [Homo sapiens]              88   3e-17
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    86   2e-16
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    83   1e-15
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    83   1e-15
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    81   3e-15
gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]       76   1e-13
gi|224548921 tripartite motif-containing 45 isoform 1 [Homo sapi...    75   2e-13
gi|224548923 tripartite motif-containing 45 isoform 2 [Homo sapi...    75   3e-13
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]    66   1e-10
gi|124487387 ring finger protein 207 [Homo sapiens]                    65   2e-10
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]    65   3e-10
gi|32454739 tripartite motif-containing 3 [Homo sapiens]               57   7e-08
gi|32454737 tripartite motif-containing 3 [Homo sapiens]               57   7e-08
gi|68160937 tripartite motif-containing 25 [Homo sapiens]              54   6e-07
gi|47174859 tripartite motif-containing 46 [Homo sapiens]              52   2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   1e-05
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             48   3e-05
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...    48   4e-05
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...    48   4e-05

>gi|67089160 promyelocytic leukemia protein isoform 11 [Homo
           sapiens]
          Length = 781

 Score = 1593 bits (4124), Expect = 0.0
 Identities = 781/781 (100%), Positives = 781/781 (100%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV 420
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV 420

Query: 421 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP 480
           SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
Sbjct: 421 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP 480

Query: 481 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSS 540
           RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSS
Sbjct: 481 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSS 540

Query: 541 PAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQER 600
           PAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQER
Sbjct: 541 PAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQER 600

Query: 601 PAVHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANA 660
           PAVHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANA
Sbjct: 601 PAVHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANA 660

Query: 661 QEHPAQLQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVG 720
           QEHPAQLQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVG
Sbjct: 661 QEHPAQLQRGISPPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVG 720

Query: 721 AGESRAQTLGAGVPPGDSVRGSMEASQVQVPLEASPITFPPPCAPERPPISPVPGARQAG 780
           AGESRAQTLGAGVPPGDSVRGSMEASQVQVPLEASPITFPPPCAPERPPISPVPGARQAG
Sbjct: 721 AGESRAQTLGAGVPPGDSVRGSMEASQVQVPLEASPITFPPPCAPERPPISPVPGARQAG 780

Query: 781 L 781
           L
Sbjct: 781 L 781


>gi|15451765 promyelocytic leukemia protein isoform 9 [Homo sapiens]
          Length = 829

 Score = 1570 bits (4065), Expect = 0.0
 Identities = 781/829 (94%), Positives = 781/829 (94%), Gaps = 48/829 (5%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPV 552
           NSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPV
Sbjct: 541 NSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPV 600

Query: 553 QSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLY 612
           QSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLY
Sbjct: 601 QSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLY 660

Query: 613 RAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGIS 672
           RAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGIS
Sbjct: 661 RAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGIS 720

Query: 673 PPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAG 732
           PPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAG
Sbjct: 721 PPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAG 780

Query: 733 VPPGDSVRGSMEASQVQVPLEASPITFPPPCAPERPPISPVPGARQAGL 781
           VPPGDSVRGSMEASQVQVPLEASPITFPPPCAPERPPISPVPGARQAGL
Sbjct: 781 VPPGDSVRGSMEASQVQVPLEASPITFPPPCAPERPPISPVPGARQAGL 829


>gi|15451779 promyelocytic leukemia protein isoform 10 [Homo
           sapiens]
          Length = 585

 Score = 1065 bits (2753), Expect = 0.0
 Identities = 524/535 (97%), Positives = 528/535 (98%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV 420
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLDV 420

Query: 421 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP 480
           SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP
Sbjct: 421 SNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSP 480

Query: 481 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSS 535
           RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENS    ++ +  +SS
Sbjct: 481 RSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESS 535


>gi|4505903 promyelocytic leukemia protein isoform 6 [Homo sapiens]
          Length = 633

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 524/583 (89%), Positives = 528/583 (90%), Gaps = 48/583 (8%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSS 535
           NSNHVASGAGEAEERVVVISSSEDSDAENS    ++ +  +SS
Sbjct: 541 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESS 583


>gi|67089149 promyelocytic leukemia protein isoform 1 [Homo sapiens]
          Length = 882

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 524/583 (89%), Positives = 528/583 (90%), Gaps = 48/583 (8%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSS 535
           NSNHVASGAGEAEERVVVISSSEDSDAENS    ++ +  +SS
Sbjct: 541 NSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESS 583


>gi|67089157 promyelocytic leukemia protein isoform 2 [Homo sapiens]
          Length = 611

 Score = 1041 bits (2693), Expect = 0.0
 Identities = 529/605 (87%), Positives = 533/605 (88%), Gaps = 54/605 (8%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPV 552
           NSNHVASGAGEAEERVVVISSSEDSDAENS       + P+  P   +  H     + P 
Sbjct: 541 NSNHVASGAGEAEERVVVISSSEDSDAENS------VSGPEVQPRTPASPHFRSQGAQPQ 594

Query: 553 QSLLR 557
           Q  LR
Sbjct: 595 QVTLR 599


>gi|109637788 promyelocytic leukemia protein isoform 5 [Homo
           sapiens]
          Length = 560

 Score = 1006 bits (2601), Expect = 0.0
 Identities = 504/552 (91%), Positives = 504/552 (91%), Gaps = 48/552 (8%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL-- 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL  
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPE 420

Query: 419 ----------------------------------------------DVSNTTTAQKRKCS 432
                                                         DVSNTTTAQKRKCS
Sbjct: 421 EAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCS 480

Query: 433 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 492
           QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP
Sbjct: 481 QTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLP 540

Query: 493 NSNHVASGAGEA 504
           NSNHVASGAGEA
Sbjct: 541 NSNHVASGAGEA 552


>gi|67089154 promyelocytic leukemia protein isoform 8 [Homo sapiens]
          Length = 435

 Score =  857 bits (2214), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL 418


>gi|15451775 promyelocytic leukemia protein isoform 7 [Homo sapiens]
          Length = 423

 Score =  857 bits (2214), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60
           MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC
Sbjct: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQC 60

Query: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120
           QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR
Sbjct: 61  QAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYR 120

Query: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180
           QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG
Sbjct: 121 QIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG 180

Query: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240
           TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL
Sbjct: 181 TRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL 240

Query: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300
           DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA
Sbjct: 241 DAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEA 300

Query: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360
           VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR
Sbjct: 301 VDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLR 360

Query: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL 418
           QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL
Sbjct: 361 QEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDL 418


>gi|239752618 PREDICTED: similar to promyelocytic leukemia protein
           [Homo sapiens]
          Length = 147

 Score =  211 bits (538), Expect = 2e-54
 Identities = 111/139 (79%), Positives = 115/139 (82%), Gaps = 6/139 (4%)

Query: 419 DVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPP 478
           DVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPP
Sbjct: 3   DVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPP 62

Query: 479 SPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAH 538
           SPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENS       + P+  P  
Sbjct: 63  SPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENS------VSGPEVQPRT 116

Query: 539 SSPAHSSPAHSSPVQSLLR 557
            +  H     + P Q  LR
Sbjct: 117 PASPHFRSQGAQPQQVTLR 135


>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
          Length = 755

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 78/324 (24%), Positives = 129/324 (39%), Gaps = 22/324 (6%)

Query: 54  FLRCQQCQAEAKCPKLLPCLHTLCSGCL----EASGMQCPICQAPWPLGADTPA--LDNV 107
           FL C+ C  + + PK LPCLHT C  CL    +   ++CP C+   P+  +  A    N 
Sbjct: 18  FLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNF 77

Query: 108 FFESL-----QRRLSVYRQIVDAQAVC-----TRCKESADFWCFECEQLLCAKCFEAHQW 157
           F   L      R     R    A A+C     T     A   C +C   LC  C + H+ 
Sbjct: 78  FVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRC 137

Query: 158 FLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCAL 217
             +     + +L       + +  R+     C  P H    L  + C+ CS+ LC  C L
Sbjct: 138 TRQTHTHRVVDLVGYRAGWYDEEARERQAAQC--PQHPGEALRFL-CQPCSQLLCRECRL 194

Query: 218 LDSSHSELKC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETE 276
               H +  C  ++  ++ R+  L+ +   +        A       A+ +L    A   
Sbjct: 195 --DPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVG 252

Query: 277 ELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRM 336
             + E    V+  + AQ++E+L  + A  +   E    RL  L+   Q  R  +A  +R+
Sbjct: 253 TQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRV 312

Query: 337 KCYASDQEVLDMHGFLRQALCRLR 360
                + E+L + G + Q L +L+
Sbjct: 313 LSLGREAEILSLEGAIAQRLRQLQ 336


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 135/641 (21%), Positives = 239/641 (37%), Gaps = 98/641 (15%)

Query: 24  PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQA--EAKCPKLLPCLHTLCSGCL 81
           P  E  +E RQ   S    E A  +  +     C  C    +++ PKLLPCLH+ C  CL
Sbjct: 27  PSGENEAESRQGPDSERGGEAARLNLLD----TCAVCHQNIQSRAPKLLPCLHSFCQRCL 82

Query: 82  EA----------------------------SG----------MQCPICQAPWPLGADTPA 103
            A                            SG          ++CP+C       A+   
Sbjct: 83  PAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQEC---AERHI 139

Query: 104 LDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ---WF 158
           +DN F +      S    +  +  VCT C+++A+   +C EC + LC  C  AHQ   + 
Sbjct: 140 IDNFFVKDTTEVPS--STVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT 197

Query: 159 LKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALL 218
             H  R   E+  ++V     G      +FC  P H+   L  +YC  C K  C  C LL
Sbjct: 198 KDHTVRQKEEVSPEAV-----GVTSQRPVFC--PFHKKEQL-KLYCETCDKLTCRDCQLL 249

Query: 219 DSSHSELKCDISAEIQQRQEE-LDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEE 277
           +  H E +     E  Q Q+  +D +   L E+         Q+   + ++ + + + E+
Sbjct: 250 E--HKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQ 307

Query: 278 LIRERVRQVVAHVRAQERELLEAVDA-------RYQRDYEEMASRLGRLDAVLQRIRTGS 330
            I+  +  ++  +  + + LL  +++       +  +  +E+A    +L+ V+   +   
Sbjct: 308 DIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAV 367

Query: 331 ALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCI 390
           +         S + +      L +A C        ++Q       + +    + +L S +
Sbjct: 368 SSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQ---NIINLGSLV 424

Query: 391 TQGKDAAVS-KKASPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGK 449
            + K++     K +P      + P  +    SN  +    + S  Q   + ++ +    +
Sbjct: 425 IEDKESQPQMPKQNPVVEQNSQPPSGLS---SNQLSKFPTQISLAQLRLQHMQQQQPPPR 481

Query: 450 EARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVV 509
                  SP+   P     V PPH      P +  I  +   PN   +A  A +A ++  
Sbjct: 482 LINFQNHSPKPNGP-----VLPPHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQ 536

Query: 510 VISSSEDSDAENSCMEPMETAEPQSSPAHSSPA-HSSPAHSSPVQSLLRAQGASSLPCGT 568
           + S        NS      T+   SSP  +S A +   A  SP+  L      SS   G+
Sbjct: 537 ISSGQGTPSTTNS------TSSTPSSPTITSAAGYDGKAFGSPMIDL------SSPVGGS 584

Query: 569 YHPPAWPPHQPAEQAATPDAEPHSEPPDH-QERPAVHRGIR 608
           Y+ P+ P    +      +        DH Q RP  +R ++
Sbjct: 585 YNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSNRTVQ 625


>gi|74027251 tripartite motif-containing 33 protein isoform beta
           [Homo sapiens]
          Length = 1110

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)

Query: 25  PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
           P   P+    P PS  P    PAS  +   +  Q  Q+  +  PKLLPCLH+ C  CL  
Sbjct: 97  PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156

Query: 82  ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
                             +   ++CP+C+           +DN F +      S   +  
Sbjct: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211

Query: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
            ++ VCT C+++A    +C EC + LC  C EAHQ   F K       E  ++SV     
Sbjct: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266

Query: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
           G      +FC  P H+   L  ++C  C +  C  C LL+  H E +     E  Q Q+ 
Sbjct: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321

Query: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
            ++ +   L E+ +       Q+   + ++       E+ I+  +  ++  +  + + LL
Sbjct: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381

Query: 299 EAVD 302
           + ++
Sbjct: 382 QQLE 385


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
           [Homo sapiens]
          Length = 1127

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 73/304 (24%), Positives = 124/304 (40%), Gaps = 41/304 (13%)

Query: 25  PPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKC-PKLLPCLHTLCSGCL-- 81
           P   P+    P PS  P    PAS  +   +  Q  Q+  +  PKLLPCLH+ C  CL  
Sbjct: 97  PAPAPASAPAPGPSAGPPPGPPASLLDTCAVCQQSLQSRREAEPKLLPCLHSFCLRCLPE 156

Query: 82  ------------------EASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIV 123
                             +   ++CP+C+           +DN F +      S   +  
Sbjct: 157 PERQLSVPIPGGSNGDIQQVGVIRCPVCRQEC---RQIDLVDNYFVKDTSEAPSSSDE-- 211

Query: 124 DAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ--WFLKHEARPLAELRNQSVREFLD 179
            ++ VCT C+++A    +C EC + LC  C EAHQ   F K       E  ++SV     
Sbjct: 212 KSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHLIRKKEDVSESV----- 266

Query: 180 GTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQE- 238
           G      +FC  P H+   L  ++C  C +  C  C LL+  H E +     E  Q Q+ 
Sbjct: 267 GASGQRPVFC--PVHKQEQL-KLFCETCDRLTCRDCQLLE--HKEHRYQFLEEAFQNQKG 321

Query: 239 ELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELL 298
            ++ +   L E+ +       Q+   + ++       E+ I+  +  ++  +  + + LL
Sbjct: 322 AIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLL 381

Query: 299 EAVD 302
           + ++
Sbjct: 382 QQLE 385


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
           [Homo sapiens]
          Length = 1050

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 138/679 (20%), Positives = 249/679 (36%), Gaps = 140/679 (20%)

Query: 24  PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQA--EAKCPKLLPCLHTLCSGCL 81
           P  E  +E RQ   S    E A  +  +     C  C    +++ PKLLPCLH+ C  CL
Sbjct: 27  PSGENEAESRQGPDSERGGEAARLNLLD----TCAVCHQNIQSRAPKLLPCLHSFCQRCL 82

Query: 82  EA----------------------------SG----------MQCPICQAPWPLGADTPA 103
            A                            SG          ++CP+C       A+   
Sbjct: 83  PAPQRYLMLPAPMLGSAETPPPVPAPGSPVSGSSPFATQVGVIRCPVCSQEC---AERHI 139

Query: 104 LDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADF--WCFECEQLLCAKCFEAHQ---WF 158
           +DN F +      S    +  +  VCT C+++A+   +C EC + LC  C  AHQ   + 
Sbjct: 140 IDNFFVKDTTEVPS--STVEKSNQVCTSCEDNAEANGFCVECVEWLCKTCIRAHQRVKFT 197

Query: 159 LKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALL 218
             H  R   E+  ++V     G      +FC  P H+   L  +YC  C K  C  C LL
Sbjct: 198 KDHTVRQKEEVSPEAV-----GVTSQRPVFC--PFHKKEQL-KLYCETCDKLTCRDCQLL 249

Query: 219 DSSHSELKCDISAEIQQRQEE-LDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEE 277
           +  H E +     E  Q Q+  +D +   L E+         Q+   + ++ + + + E+
Sbjct: 250 E--HKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRIIEVNQNQKQVEQ 307

Query: 278 LIRERVRQVVAHVRAQERELLEAVDA-------RYQRDYEEMASRLGRLDAVLQ----RI 326
            I+  +  ++  +  + + LL  +++       +  +  +E+A    +L+ V+      +
Sbjct: 308 DIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQLEHVMHFSKWAV 367

Query: 327 RTGSAL---------------VQRMKCYASD----------------QEVLDMHGFL--- 352
            +GS+                + R +C AS                 Q ++++   +   
Sbjct: 368 SSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQNIINLGSLVIED 427

Query: 353 RQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRD 412
           +++  ++ ++ P   Q +    G    ++        + Q +   + ++   +     R 
Sbjct: 428 KESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQVMAQRQQVQRR 487

Query: 413 PIDVDL-DVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSP 471
           P  V L +       Q+   S  Q P ++I  ++                 P  +  V P
Sbjct: 488 PAPVGLPNPRMQGPIQQPSISHQQPPPRLINFQNHS---------------PKPNGPVLP 532

Query: 472 PHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAE 531
           PH      P +  I  +   PN   +A  A +A ++  + S        NS      T+ 
Sbjct: 533 PHPQQLRYPPNQNIPRQAIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNS------TSS 586

Query: 532 PQSSPAHSSPA-HSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEP 590
             SSP  +S A +   A  SP+  L      SS   G+Y+ P+ P    +      +   
Sbjct: 587 TPSSPTITSAAGYDGKAFGSPMIDL------SSPVGGSYNLPSLPDIDCSSTIMLDNIVR 640

Query: 591 HSEPPDH-QERPAVHRGIR 608
                DH Q RP  +R ++
Sbjct: 641 KDTNIDHGQPRPPSNRTVQ 659


>gi|5032179 tripartite motif-containing 28 protein [Homo sapiens]
          Length = 835

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 78/369 (21%), Positives = 149/369 (40%), Gaps = 55/369 (14%)

Query: 4   APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLR----CQQ 59
           A + SP P +  A  ++ +      PS     S S + +  A    E  + L     C++
Sbjct: 15  AASGSPGPGEGSAGGEKRST----APSAAASASASAAASSPAGGGAEALELLEHCGVCRE 70

Query: 60  CQAEAKCPKLLPCLHTLCSGCL------------------EASGMQCPICQAPWPLGADT 101
                + P+LLPCLH+ CS CL                  + + + CP+C+         
Sbjct: 71  RLRPEREPRLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---FSK 127

Query: 102 PALDNVFFESLQRRLSVYRQIVDAQAVCTRCKES--ADFWCFECEQLLCAKCFEAHQ--- 156
             ++N F      + +   Q  DA   CT C+++  A  +C EC + LC  C EAHQ   
Sbjct: 128 DIVENYFMRDSGSKAATDAQ--DANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVK 185

Query: 157 WFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
           +   H  R     +++      DG R    ++C+   H    L   +C  C    C  C 
Sbjct: 186 YTKDHTVRSTGPAKSR------DGER---TVYCNVHKHEPLVL---FCESCDTLTCRDCQ 233

Query: 217 LLDSSHSELKCDISAEIQQRQEELDA-MTQALQEQDSAFGAVHAQMHAAVGQLGRARAET 275
           L  ++H + +     +  + Q +L A + + L ++ +       ++ +++ Q+   +   
Sbjct: 234 L--NAHKDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRV 291

Query: 276 EELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQR 335
           +  ++  + Q++  +  + R L+   DA  Q+  E    RL R    + +I+     + R
Sbjct: 292 QVDVKMAILQIMKELNKRGRVLVN--DA--QKVTEGQQERLERQHWTMTKIQKHQEHILR 347

Query: 336 MKCYASDQE 344
              +A + +
Sbjct: 348 FASWALESD 356


>gi|224548921 tripartite motif-containing 45 isoform 1 [Homo
           sapiens]
          Length = 580

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 87/403 (21%), Positives = 152/403 (37%), Gaps = 87/403 (21%)

Query: 57  CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
           C  C    K P+LLPCLHT+C+ CLE                                  
Sbjct: 29  CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88

Query: 85  --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
             G+ CP+C  Q   P+G       D  A+++V  ESL+              VC  C +
Sbjct: 89  QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140

Query: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
              +  C  C+  LC  C +AH+   K     + +L++      L G +R    I C  P
Sbjct: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192

Query: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
            H    L  ++C  C +P+C  C +    H E  CD ++ +  +      E L      +
Sbjct: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249

Query: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
           +  + A   +H    A   ++    A+        ++ +  H   +++ L +  D R Q+
Sbjct: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306

Query: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEE---- 363
           +   +  +  +L+ +L  +RTG    + +    SD E+L     + + L +L + +    
Sbjct: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVVVERLRKLNKVQYSTR 365

Query: 364 ----------PQSLQAAVR-TDGFDEFKVRLQDLSSCITQGKD 395
                     PQ      R  + +     +  D + C+ QG+D
Sbjct: 366 PGVNDKIRFCPQEKAGQCRGYEIYGTINTKEVDPAKCVLQGED 408


>gi|224548923 tripartite motif-containing 45 isoform 2 [Homo
           sapiens]
          Length = 562

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 77/339 (22%), Positives = 131/339 (38%), Gaps = 72/339 (21%)

Query: 57  CQQCQAEAKCPKLLPCLHTLCSGCLEAS-------------------------------- 84
           C  C    K P+LLPCLHT+C+ CLE                                  
Sbjct: 29  CPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFSVVDIRGGDSDTSSEGSIFQELKPRSLQS 88

Query: 85  --GMQCPIC--QAPWPLGA------DTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKE 134
             G+ CP+C  Q   P+G       D  A+++V  ESL+              VC  C +
Sbjct: 89  QIGILCPVCDAQVDLPMGGVKALTIDHLAVNDVMLESLRGE--------GQGLVCDLCND 140

Query: 135 -SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDG-TRKTNNIFCSNP 192
              +  C  C+  LC  C +AH+   K     + +L++      L G +R    I C  P
Sbjct: 141 REVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVDLKD------LKGYSRIGKPILC--P 192

Query: 193 NHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQ-----EELDAMTQAL 247
            H    L  ++C  C +P+C  C +    H E  CD ++ +  +      E L      +
Sbjct: 193 VHPAEELR-LFCEFCDRPVCQDCVV--GEHREHPCDFTSNVIHKHGDSVWELLKGTQPHV 249

Query: 248 QEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQR 307
           +  + A   +H    A   ++    A+        ++ +  H   +++ L +  D R Q+
Sbjct: 250 EALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEEH---RDKLLKQLEDIRAQK 306

Query: 308 DYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVL 346
           +   +  +  +L+ +L  +RTG    + +    SD E+L
Sbjct: 307 E-NSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEIL 344


>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
          Length = 771

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 86/387 (22%), Positives = 142/387 (36%), Gaps = 79/387 (20%)

Query: 24  PPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCLE- 82
           PP +      + +  PSP  R    + + QFL C  C    K PK+LPCLHT C  CL+ 
Sbjct: 21  PPCQWSRMASEGTNIPSPVVR----QIDKQFLICSICLERYKNPKVLPCLHTFCERCLQN 76

Query: 83  -----ASGMQCPICQAPWPLGAD-TPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESA 136
                +  + CP+C+    L      AL N FF            I +   V  R     
Sbjct: 77  YIPAHSLTLSCPVCRQTSILPEKGVAALQNNFF------------ITNLMDVLQRT---- 120

Query: 137 DFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRT 196
                                       P +     S+ E +        + C  PNH  
Sbjct: 121 ----------------------------PGSNAEESSILETVTAVAAGKPLSC--PNH-D 149

Query: 197 PTLTSIYCRGCSKPLCCSCALLDSSHSE-----LKCDISAEIQQRQEELDAMTQALQEQD 251
             +   YC+ C   +C  C   +  H+E     LK  +       Q +LDA+ + L E D
Sbjct: 150 GNVMEFYCQSCETAMCRECT--EGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEID 207

Query: 252 SAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQRDYEE 311
           SA   +   +H    QL   +A   + I     ++   +  ++  LL  ++  Y   ++ 
Sbjct: 208 SALQFISEIIH----QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKV 263

Query: 312 MASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQE-------EP 364
           + S+L  L    + I++ S    +   + ++ EVL +   + + L  L  +       E 
Sbjct: 264 LQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPREN 323

Query: 365 QSLQAAVRTDGFDEFKVRLQDLSSCIT 391
             L   V T+G    K  + +L + +T
Sbjct: 324 DQLDFIVETEG---LKKSIHNLGTILT 347


>gi|124487387 ring finger protein 207 [Homo sapiens]
          Length = 634

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 66/304 (21%), Positives = 118/304 (38%), Gaps = 24/304 (7%)

Query: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCLEASG----MQCPICQAPWPLGADT--PALDNV- 107
           L C  C  + + P LL C H  C+GCL        + CP+CQ    L   +  P +D + 
Sbjct: 23  LVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLL 82

Query: 108 --FFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARP 165
               +S    +   R   +    C+       ++C  C Q LCA+C +       H AR 
Sbjct: 83  QFLVDSSGDGVEAVR-CANCDLECSEQDVETTYFCNTCGQPLCARCRDE-----THRARM 136

Query: 166 LAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSEL 225
            A        + +   +++ ++      H  P L  ++       LC  C       S  
Sbjct: 137 FAR------HDIVALGQRSRDVPQKCTLHAEPYL--LFSTDKKLLLCIRCFRDMQKESRA 188

Query: 226 KC-DISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVR 284
            C D+ +   Q  E L+    A++   +A     A + A V ++  + AE E+ I     
Sbjct: 189 HCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFG 248

Query: 285 QVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQE 344
            +   +  ++  LL+AV ++Y+   +    +L  L  +L  ++    +       A+  E
Sbjct: 249 SMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAE 308

Query: 345 VLDM 348
            LD+
Sbjct: 309 FLDL 312


>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
          Length = 744

 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 84/372 (22%), Positives = 137/372 (36%), Gaps = 79/372 (21%)

Query: 39  PSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCLE------ASGMQCPICQ 92
           PSP  R    + + QFL C  C    K PK+LPCLHT C  CL+      +  + CP+C+
Sbjct: 9   PSPVVR----QIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTLSCPVCR 64

Query: 93  APWPLGAD-TPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKC 151
               L      AL N FF            I +   V  R                    
Sbjct: 65  QTSILPEKGVAALQNNFF------------ITNLMDVLQRT------------------- 93

Query: 152 FEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPL 211
                        P +     S+ E +        + C  PNH    +   YC+ C   +
Sbjct: 94  -------------PGSNAEESSILETVTAVAAGKPLSC--PNH-DGNVMEFYCQSCETAM 137

Query: 212 CCSCALLDSSHSE-----LKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVG 266
           C  C   +  H+E     LK  +       Q +LDA+ + L E DSA   +   +H    
Sbjct: 138 CRECT--EGEHAEHPTVPLKDVVEQHKASLQVQLDAVNKRLPEIDSALQFISEIIH---- 191

Query: 267 QLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRI 326
           QL   +A   + I     ++   +  ++  LL  ++  Y   ++ + S+L  L    + I
Sbjct: 192 QLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHKVLQSQLDTLLQGQESI 251

Query: 327 RTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQE-------EPQSLQAAVRTDGFDEF 379
           ++ S    +   + ++ EVL +   + + L  L  +       E   L   V T+G    
Sbjct: 252 KSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQDFPLHPRENDQLDFIVETEG---L 308

Query: 380 KVRLQDLSSCIT 391
           K  + +L + +T
Sbjct: 309 KKSIHNLGTILT 320


>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 80/325 (24%), Positives = 129/325 (39%), Gaps = 60/325 (18%)

Query: 33  RQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCL------EASGM 86
           R+ SP P   E  P  +   QFL C  C    +CPK+LPCLHT C  CL      ++  +
Sbjct: 4   REDSPGP---EVQPMDK---QFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTL 57

Query: 87  QCPICQAPWPLGAD-TPALDNVFF-----ESLQRRLSVYRQIVDAQAVCT------RCK- 133
            CP+C+    L      AL N FF     E++Q+         D   +         C  
Sbjct: 58  SCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPN 117

Query: 134 ---ESADFWCFECEQLLCAKCFEA-HQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFC 189
              ++ +F+C  CE  +C +C    H+       R + E    +++  L+  R       
Sbjct: 118 HEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVR------- 170

Query: 190 SNPNHRTPTLTSIYC--RGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEELDAMTQAL 247
                R P L++      G S+        L    +E    ISA  +  ++ L    QAL
Sbjct: 171 ----GRLPQLSAAIALVGGISQQ-------LQERKAEALAQISAAFEDLEQALQQRKQAL 219

Query: 248 -QEQDSAFGAVHAQMHAAV-----GQ--LGRARAETEELIRERVRQVVAHVRAQERELLE 299
             + ++  GA    + + +     GQ  +G + +  E+ +R      V  VR   RE L 
Sbjct: 220 VSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLA 279

Query: 300 AVDARYQRDYEEMASRLGRLDAVLQ 324
           A+ A   + + E      +L+ VL+
Sbjct: 280 ALAA---QAFPERPHENAQLELVLE 301


>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
          Length = 744

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 80/325 (24%), Positives = 129/325 (39%), Gaps = 60/325 (18%)

Query: 33  RQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCL------EASGM 86
           R+ SP P   E  P  +   QFL C  C    +CPK+LPCLHT C  CL      ++  +
Sbjct: 4   REDSPGP---EVQPMDK---QFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTL 57

Query: 87  QCPICQAPWPLGAD-TPALDNVFF-----ESLQRRLSVYRQIVDAQAVCT------RCK- 133
            CP+C+    L      AL N FF     E++Q+         D   +         C  
Sbjct: 58  SCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPN 117

Query: 134 ---ESADFWCFECEQLLCAKCFEA-HQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFC 189
              ++ +F+C  CE  +C +C    H+       R + E    +++  L+  R       
Sbjct: 118 HEGKTMEFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVR------- 170

Query: 190 SNPNHRTPTLTSIYC--RGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEELDAMTQAL 247
                R P L++      G S+        L    +E    ISA  +  ++ L    QAL
Sbjct: 171 ----GRLPQLSAAIALVGGISQQ-------LQERKAEALAQISAAFEDLEQALQQRKQAL 219

Query: 248 -QEQDSAFGAVHAQMHAAV-----GQ--LGRARAETEELIRERVRQVVAHVRAQERELLE 299
             + ++  GA    + + +     GQ  +G + +  E+ +R      V  VR   RE L 
Sbjct: 220 VSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSFAEQALRLGSAPEVLLVRKHMRERLA 279

Query: 300 AVDARYQRDYEEMASRLGRLDAVLQ 324
           A+ A   + + E      +L+ VL+
Sbjct: 280 ALAA---QAFPERPHENAQLELVLE 301


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 76/371 (20%), Positives = 126/371 (33%), Gaps = 58/371 (15%)

Query: 43  ERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCL------EASGMQCPICQAPW- 95
           E  P +EE    L C  C    K P   PC H  C  CL      + S   CP C+A + 
Sbjct: 3   ELCPLAEE----LSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQ 58

Query: 96  --PLGADTPALDNVFFESLQRRLS-------------VYRQIVDAQAVCTRC-KESADFW 139
             P       L NV  + LQ  L+                   +AQ  C  C KE+A   
Sbjct: 59  ARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKT 118

Query: 140 CFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTL 199
           C  C    C +  + H      +  PL       +R       +    FC  P H     
Sbjct: 119 CLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFC--PEH----- 171

Query: 200 TSIYCRGCS-KPLCCSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVH 258
           +   C  C  +   CS A L  + ++L+  +  ++     +++  ++AL +  +    V 
Sbjct: 172 SECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVR 231

Query: 259 AQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQ------------ 306
              +  V QL +   E + L+          ++ +E+ +    D  YQ            
Sbjct: 232 MTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTL 291

Query: 307 ----------RDYEEMASRLGRLDAVLQR-IRTGSALVQRMKCYASDQEVLDMHGFLRQA 355
                     RD  E   +  +L  +  + +      +         Q  +D+   L+Q 
Sbjct: 292 KEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQC 351

Query: 356 LCRLRQEEPQS 366
           + RL++  P S
Sbjct: 352 IGRLQEPTPSS 362


>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
          Length = 759

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 63/256 (24%), Positives = 106/256 (41%), Gaps = 32/256 (12%)

Query: 88  CPICQAPWPLGADTPALDNVFFE-SLQRRLSVYRQIVDAQA--VCTRCKE---SADFWCF 141
           CP CQ    LG     L  +F   +L+R +  YRQ V      +C  CK     A   C 
Sbjct: 130 CPACQGDVELGER--GLAGLFRNLTLERVVERYRQSVSVGGAILCQLCKPPPLEATKGCT 187

Query: 142 ECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTS 201
           EC    C +CF+    +   +A+    L   S R           + C  P+H+     +
Sbjct: 188 ECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFR--------PKGLMC--PDHKEE--VT 235

Query: 202 IYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEEL-DAMTQALQEQDSAFGAVHAQ 260
            YC+ C + +C  C +  +        + +  Q  +++L  ++T  L  QD+    +  +
Sbjct: 236 HYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQI-CE 294

Query: 261 MHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLD 320
           +  AV     +  + +E + + VR + A +  +   LL+A++       E    RL RL 
Sbjct: 295 LEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIE-------ECQQERLARLS 347

Query: 321 AVLQRIRT---GSALV 333
           A +Q  R+   GS LV
Sbjct: 348 AQIQEHRSLLDGSGLV 363



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 15/34 (44%), Positives = 17/34 (50%), Gaps = 1/34 (2%)

Query: 55 LRCQQCQAEAKCPKLLPCLHTLCSGCL-EASGMQ 87
          L C  CQ   K P +LPC H +C  C  E  G Q
Sbjct: 31 LLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQ 64


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 76/328 (23%), Positives = 122/328 (37%), Gaps = 48/328 (14%)

Query: 454 ARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISS 513
           A + P QP+P   +A+ PP +  P    +P +G     P +    SG           + 
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG-----------TK 313

Query: 514 SEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPA 573
           +      ++   P+    P S P  +    + P+ S+P           +LP     PPA
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP-------PSLQTLP----SPPA 362

Query: 574 WPPHQPAEQAATPDAEPHSEPPDHQERPAVH--RGIRYLLYRAQRAIRLRHALRLHPQLH 631
            PP Q      TP   P   PP  Q  P +     +     +A  +     +L+    L 
Sbjct: 363 TPPSQAPPSMTTP---PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419

Query: 632 RAPIR------TWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGISPPHR--IRGAVRS 683
              ++      T SP   QAS  + + P + P ++    A L    SPP +  +  AV  
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP 479

Query: 684 RSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAGVPPGDSVRGSM 743
            S  L  + H  Q L++      +S + Q  +SS++       +T  +  PP      + 
Sbjct: 480 LSSPL--TIHPLQALSS-----LASHSPQAPLSSLI---MPPLETQSSLAPPS---LQTP 526

Query: 744 EASQVQVPLEASPITFPPPCAPERPPIS 771
            AS    PLE  P   PPP      P++
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLT 554



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 81/340 (23%), Positives = 120/340 (35%), Gaps = 51/340 (15%)

Query: 461 PRPSTSKAVSPPHLDGPPSPRSPVI---GSEVFLPNSNHVASGAGEAEERVVVISSSEDS 517
           P  + S  ++ PHL+ PP P    +    S +  P     +S A    +    ++S    
Sbjct: 545 PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604

Query: 518 DAENSCMEPMETAEPQSSPAHSSP---AHSSPAHSSPVQSLL--RAQGASSLPCGTYHPP 572
              +  + P+ T  PQ+ P  + P   A  SP  S P+  L     Q  ++L       P
Sbjct: 605 GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664

Query: 573 AWPPHQPAEQA-----ATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAIRLRHALRLH 627
             PP  P  QA     A+P   P + PP  Q  P++          A   +++  +    
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSPSATPPS-QAPPSL----------AAPPLQVPPSPPAS 713

Query: 628 PQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGISPPHRIRGAVRSRSRS 687
           P +  +P  T  P   QA  P    PL  P +    P  +    +PP R+   + +    
Sbjct: 714 PPM--SPSATPPP---QAPPPLAAPPLQVPPSPPASP-PMSPSATPPPRVPPLLAAPPLQ 767

Query: 688 LRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGAGVPPGDSVRGSMEASQ 747
           +  S   S        LP S +A     +    A       L A   P  S  G    S 
Sbjct: 768 VPPSPPAS--------LPMSPLAKPPPQAPPALA----TPPLQALPSPPASFPGQAPFSP 815

Query: 748 VQVPLEASPITFPPPCAP--------ERPPISPVPGARQA 779
               L  SP+  PPP AP        + PP  P     QA
Sbjct: 816 -SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 1   MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAP 46
           +E  P  +P P Q P  P   T PPPETPS    P P   P   +P
Sbjct: 558 LETPPCPAPCPLQAPPSPL--TTPPPETPSSIATPPPQAPPALASP 601



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 64/259 (24%), Positives = 94/259 (36%), Gaps = 51/259 (19%)

Query: 456 SSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSE 515
           +SP     +T    +PP L  PP    P        P ++   S +     RV  + ++ 
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPS-------PPASPPMSPSATPPPRVPPLLAAP 764

Query: 516 D-----SDAENSCMEPMETAEPQSSPAHSSP---AHSSPAHSSPVQSLLRAQGASSLPCG 567
                 S   +  M P+    PQ+ PA ++P   A  SP  S P Q+      ++SLP  
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP--SASLPMS 822

Query: 568 TYHPPAWPPHQPAEQAA-------TPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAIRL 620
               P  PP  P   AA       +P A P  + P     P     +      +   + L
Sbjct: 823 PLATP--PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV------SGPRLTL 874

Query: 621 RHALRLHPQLHRAPIRTWS-PHVVQASTPAITGP---------------LNHPANAQE-- 662
             A    P   R+P  T S P +   S+ A + P                + P +A+   
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934

Query: 663 -HPAQLQRGISPPHRIRGA 680
            HPA   RG +PP   RGA
Sbjct: 935 CHPAAWSRGPAPPLAFRGA 953



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 89/400 (22%), Positives = 133/400 (33%), Gaps = 71/400 (17%)

Query: 403 SPEAASTPRDPIDVDLDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPR 462
           +P A +T   P+      S TT             +K +++ +EE      A  +P++  
Sbjct: 103 APPAKNTSPGPVSSPGRASGTTRPGP-------LGQKGLRISAEETVARGKATEAPKRSA 155

Query: 463 PSTS--KAVSPPHLDGPPSP----RSPVIGSEVFLPNSNHVASGAGEAE-ERVVVISSSE 515
            S    +  S P   G PSP    RS   G+EV LP     A      E  R  V S+SE
Sbjct: 156 LSAGARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214

Query: 516 DSDAENS-----------------CMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLLRA 558
            S  E S                       +A P SSPA S P+      +    S  + 
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274

Query: 559 QGASSLPCGTYHPPAWPPHQPAEQA-----ATPDAEPHSEPPDHQERPAVHRGIRYLLYR 613
           +G  +L      P   PP + A  A     ++P A P       +  P        L   
Sbjct: 275 KGLQAL----RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT 330

Query: 614 AQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHPAQLQRGIS- 672
              +  L   L L P    AP     P +    +P  T P   P +    P Q    +  
Sbjct: 331 LPPSPPLATPLPLAPPSPSAP-----PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385

Query: 673 -PPHRIRGAVRSRSRSLRGSSHLSQWLNNFFALPFSSMASQLDMSSVVGAGESRAQTLGA 731
            PP ++  ++ S S                      +  S L +SS+       + TL A
Sbjct: 386 IPPIQVPHSLTSPS--------------------LQAPPSPLALSSLQATTSLGSPTLQA 425

Query: 732 GVPPGDSVRGSMEASQVQVPLEASPITFPPPCAPERPPIS 771
                  +  S   +Q  +   + P + PP   P + P+S
Sbjct: 426 ---THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS 462



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 15/43 (34%), Positives = 20/43 (46%), Gaps = 1/43 (2%)

Query: 4   APARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAP 46
           +P+ +P PQ  P     P   PP  P+     SPS +P  R P
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPM-SPSATPPPRVP 758


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 72/325 (22%), Positives = 120/325 (36%), Gaps = 29/325 (8%)

Query: 383  LQDLSSCITQGK---DAAVSKKASPEAAST-PRDPIDVDLDVSNTTTAQKRKCSQTQCPR 438
            ++D+    ++G+   D++   KA P+      R P   +L+    T  ++R  S++   +
Sbjct: 1466 MKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ 1525

Query: 439  KVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVA 498
            K +   +  G+ +R   S     +PS S        +   S  SP   ++   P      
Sbjct: 1526 KTVA-RTPLGQRSRSGSSQELDVKPSASPQ------ERSESDSSPDSKAKTRTPLRQRSR 1578

Query: 499  SGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPAHSSPAHSSPVQSLL-- 556
            SG+    +    +S        +    P    +P+++P   S + SSP   +P    L  
Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSS----PEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPR 1634

Query: 557  ------RAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPAVHRGIRY- 609
                   ++G    P G+    + P H P  + A   +    EP      P   R  R  
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694

Query: 610  --LLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQASTPAITGPLNHPANAQEHP--- 664
              L  +A+ + R R A        R P R      V +  PA     +    +   P   
Sbjct: 1695 PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTK 1754

Query: 665  AQLQRGISPPHRIRGAVRSRSRSLR 689
               +RG SP  + RG  RSRSRS R
Sbjct: 1755 TTSRRGRSPSPKPRGLQRSRSRSRR 1779



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 66/296 (22%), Positives = 103/296 (34%), Gaps = 32/296 (10%)

Query: 403 SPEAASTPRDPIDVDLDVSNTTTAQKRKCSQ--TQCPRKVIKMESEEGKEARLARSSPEQ 460
           SP  AS  R   D       TT+ Q+    +  T+ P    + + ++ KE    R SP  
Sbjct: 295 SPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSP 354

Query: 461 PRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAE 520
            R ST           PP+P +P++            A   G + + +     S++    
Sbjct: 355 ERSSTGPE--------PPAP-TPLL------------AERHGGSPQPLATTPLSQEPVNP 393

Query: 521 NSCMEPMETAEPQSSP---AHSSPAHSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPH 577
            S   P     P  SP     SS + SSP    P +    A  +   P      PA  P 
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP-----KPAPAPG 448

Query: 578 QPAEQAATPDAEPHSEPPDHQERPAVHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRT 637
              E +++P ++  S     +++   H   R +      A   R   R      R   R+
Sbjct: 449 SHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRS 508

Query: 638 WSPHVVQASTPAITGPLNHPANAQEHPAQLQRGISPPHRIRGAVRSRSRSLRGSSH 693
            SP   ++ +    G    P       +  + G S     +   RSRS + RG SH
Sbjct: 509 RSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS-ARRGRSH 563



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 49/225 (21%), Positives = 78/225 (34%), Gaps = 22/225 (9%)

Query: 423  TTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRS 482
            +T AQ+        P K  +  S     +  + SS      S+S   S    +G   P  
Sbjct: 2512 STGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ 2571

Query: 483  PVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSCMEPMETAEPQSSPAHSSPA 542
            P +  +        V S     +E V      E + A+        ++   SS + SS +
Sbjct: 2572 PEVALK-------RVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624

Query: 543  HSSPAHSSPVQSLLRAQGASSLPCGTYHPPAWPPHQPAEQAATPDAEPHSEPPDHQERPA 602
             SS + SS   S   +  +SS    +       P +P  QA    A P   PP  +   +
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPS-------PAKPGPQALPKPASPKKPPPGERRSRS 2677

Query: 603  VHRGIRYLLYRAQRAIRLRHALRLHPQLHRAPIRTWSPHVVQAST 647
              + I         ++R   +L   P   R P    SP   Q+S+
Sbjct: 2678 PRKPI--------DSLRDSRSLSYSPVERRRPSPQPSPRDQQSSS 2714



 Score = 33.9 bits (76), Expect = 0.60
 Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 24/70 (34%)

Query: 3    PAPARSPRPQQDPARPQEPTMPPPE----------------------TPSEGRQPSPSPS 40
            P+PA+ P PQ  P +P  P  PPP                       +P E R+PSP PS
Sbjct: 2649 PSPAK-PGPQALP-KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS 2706

Query: 41   PTERAPASEE 50
            P ++  +S E
Sbjct: 2707 PRDQQSSSSE 2716



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 7/74 (9%)

Query: 8   SPRPQQDPARPQEPTMPPPE-TPSEGRQPSPSP------SPTERAPASEEEFQFLRCQQC 60
           SP+P       QEP  PP E +P+  R P  SP      S +E +P S +  +  R    
Sbjct: 377 SPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASS 436

Query: 61  QAEAKCPKLLPCLH 74
             E+  P   P  H
Sbjct: 437 SPESPKPAPAPGSH 450



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 19/73 (26%), Positives = 31/73 (42%), Gaps = 4/73 (5%)

Query: 707  SSMASQLDMSSVVGAGESRAQTLGAGVPPGDSVRGSMEASQVQVPLEASPITFPPPCAPE 766
            SS +S    SS   +  S + +  +      S   S  +S    P +  P   P P +P+
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666

Query: 767  RPPISPVPGARQA 779
            +PP    PG R++
Sbjct: 2667 KPP----PGERRS 2675



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 14/39 (35%), Positives = 20/39 (51%)

Query: 10   RPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPAS 48
            +P+    R   PT  P E   EGR P P+P+  +R  +S
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSS 2609


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 41/179 (22%), Positives = 75/179 (41%), Gaps = 14/179 (7%)

Query: 129 CTRCKE--SADFWCFECEQLLCAKCFEAHQWFLKHEARPLAEL--RNQSVREFLDGTRKT 184
           C+ CKE  +A   C  C + LC+ C E H    +H   P      R Q     ++G    
Sbjct: 5   CSECKEKRAAHILCTYCNRWLCSSCTEEH----RHSPVPGGPFFPRAQKGSPGVNGGPGD 60

Query: 185 NNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEE-LDAM 243
             ++C  P H T  +  ++C  C    C SC +++  H E +C    E+ Q Q   L+ +
Sbjct: 61  FTLYC--PLH-TQEVLKLFCETCDMLTCHSCLVVE--HKEHRCRHVEEVLQNQRMLLEGV 115

Query: 244 TQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVD 302
           T  +  + S+      Q+   + ++     + E  I+     ++  +  Q   L+E ++
Sbjct: 116 TTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELE 174



 Score = 30.0 bits (66), Expect = 8.6
 Identities = 15/45 (33%), Positives = 22/45 (48%), Gaps = 1/45 (2%)

Query: 7   RSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEE 51
           + P+ Q  P  P  P  PPP  P   +QP P   P++   +S+ E
Sbjct: 451 QQPQQQLPPPPPPLPH-PPPPLPPPPQQPHPPLPPSQHLASSQHE 494


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 57/276 (20%)

Query: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCL----EASGMQ------CPICQAPWPLGADTP-- 102
           + C  CQ   + P  + C H  C  CL    E  G        CP+C+ P+  G+  P  
Sbjct: 14  VNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNW 73

Query: 103 ALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQW----- 157
            L NV  E+++R   V    +  + VC    E   F+C + E  LC  C EA +      
Sbjct: 74  QLANV-VENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHATHTM 132

Query: 158 -FLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
            FL+  A P  E  ++ ++  L   R+      S  N R   L +               
Sbjct: 133 RFLEDAAAPYREQIHKCLK-CLRKEREEIQEIQSRENKRMQVLLT--------------- 176

Query: 217 LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETE 276
                       +S + QQ   E   + + L+EQ S    + AQ+ +  G + R R E +
Sbjct: 177 -----------QVSTKRQQVISEFAHLRKFLEEQQS---ILLAQLESQDGDILRQRDEFD 222

Query: 277 ELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEM 312
            L+   + +  A        L+E ++ + +R   E+
Sbjct: 223 LLVAGEICRFSA--------LIEELEEKNERPAREL 250


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 65/276 (23%), Positives = 106/276 (38%), Gaps = 57/276 (20%)

Query: 55  LRCQQCQAEAKCPKLLPCLHTLCSGCL----EASGMQ------CPICQAPWPLGADTP-- 102
           + C  CQ   + P  + C H  C  CL    E  G        CP+C+ P+  G+  P  
Sbjct: 14  VNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSFRPNW 73

Query: 103 ALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQW----- 157
            L NV  E+++R   V    +  + VC    E   F+C + E  LC  C EA +      
Sbjct: 74  QLANV-VENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHATHTM 132

Query: 158 -FLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCA 216
            FL+  A P  E  ++ ++  L   R+      S  N R   L +               
Sbjct: 133 RFLEDAAAPYREQIHKCLK-CLRKEREEIQEIQSRENKRMQVLLT--------------- 176

Query: 217 LLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETE 276
                       +S + QQ   E   + + L+EQ S    + AQ+ +  G + R R E +
Sbjct: 177 -----------QVSTKRQQVISEFAHLRKFLEEQQS---ILLAQLESQDGDILRQRDEFD 222

Query: 277 ELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEM 312
            L+   + +  A        L+E ++ + +R   E+
Sbjct: 223 LLVAGEICRFSA--------LIEELEEKNERPAREL 250


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.129    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,586,675
Number of Sequences: 37866
Number of extensions: 2112144
Number of successful extensions: 29862
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 267
Number of HSP's successfully gapped in prelim test: 893
Number of HSP's that attempted gapping in prelim test: 20395
Number of HSP's gapped (non-prelim): 9093
length of query: 781
length of database: 18,247,518
effective HSP length: 110
effective length of query: 671
effective length of database: 14,082,258
effective search space: 9449195118
effective search space used: 9449195118
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.