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Search of human proteins with 65507253
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|65507253 hypothetical protein LOC55196 [Homo sapiens]
(1747 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|65507253 hypothetical protein LOC55196 [Homo sapiens] 3476 0.0
gi|87299628 biorientation of chromosomes in cell division 1-like... 58 7e-08
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 54 1e-06
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 54 1e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 53 2e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 50 2e-05
gi|47578107 delangin isoform B [Homo sapiens] 50 3e-05
gi|47578105 delangin isoform A [Homo sapiens] 50 3e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 49 3e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 47 1e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 47 1e-04
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 47 2e-04
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 46 4e-04
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 45 8e-04
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 45 8e-04
gi|148613886 regulatory factor X domain containing 2 [Homo sapiens] 44 0.001
gi|71061468 centromere protein E [Homo sapiens] 44 0.001
gi|118498356 kinectin 1 isoform a [Homo sapiens] 43 0.002
gi|33620775 kinectin 1 isoform a [Homo sapiens] 43 0.002
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 43 0.002
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 42 0.007
gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 41 0.009
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 41 0.012
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 41 0.012
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 40 0.015
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 40 0.015
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 40 0.015
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 40 0.015
gi|156415994 UTP11-like, U3 small nucleolar ribonucleoprotein [H... 40 0.015
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 40 0.015
>gi|65507253 hypothetical protein LOC55196 [Homo sapiens]
Length = 1747
Score = 3476 bits (9014), Expect = 0.0
Identities = 1747/1747 (100%), Positives = 1747/1747 (100%)
Query: 1 MNWNEKPKSATLPPLYPKSQPPFLHQSLINQITTTSQSSFSYPGSNQEACMYPGNSNPIS 60
MNWNEKPKSATLPPLYPKSQPPFLHQSLINQITTTSQSSFSYPGSNQEACMYPGNSNPIS
Sbjct: 1 MNWNEKPKSATLPPLYPKSQPPFLHQSLINQITTTSQSSFSYPGSNQEACMYPGNSNPIS 60
Query: 61 QPLLNIQNYPQQISVSDMHNGTVVASHTSVERITYANVNGPKQLTHNLQMSSGVTQNVWL 120
QPLLNIQNYPQQISVSDMHNGTVVASHTSVERITYANVNGPKQLTHNLQMSSGVTQNVWL
Sbjct: 61 QPLLNIQNYPQQISVSDMHNGTVVASHTSVERITYANVNGPKQLTHNLQMSSGVTQNVWL 120
Query: 121 NSPMRNPVHSHIGATVSHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAY 180
NSPMRNPVHSHIGATVSHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAY
Sbjct: 121 NSPMRNPVHSHIGATVSHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAY 180
Query: 181 QGNQGLNQSFSEQQVDWTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHT 240
QGNQGLNQSFSEQQVDWTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHT
Sbjct: 181 QGNQGLNQSFSEQQVDWTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHT 240
Query: 241 SLQVKNSQLPNSVLTLPSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKH 300
SLQVKNSQLPNSVLTLPSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKH
Sbjct: 241 SLQVKNSQLPNSVLTLPSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKH 300
Query: 301 LSMEVPQSREMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNSPIRSSVDG 360
LSMEVPQSREMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNSPIRSSVDG
Sbjct: 301 LSMEVPQSREMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNSPIRSSVDG 360
Query: 361 VQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDL 420
VQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDL
Sbjct: 361 VQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDL 420
Query: 421 LMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNK 480
LMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNK
Sbjct: 421 LMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNK 480
Query: 481 TQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLN 540
TQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLN
Sbjct: 481 TQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLN 540
Query: 541 TQLSSENVTKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLK 600
TQLSSENVTKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLK
Sbjct: 541 TQLSSENVTKVEQNSPAVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLK 600
Query: 601 DANQTIQDSKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGM 660
DANQTIQDSKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGM
Sbjct: 601 DANQTIQDSKPDSCEMNPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGM 660
Query: 661 PAKSDSSCSMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVV 720
PAKSDSSCSMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVV
Sbjct: 661 PAKSDSSCSMEVLATCLSLWKKQPSDTAKEKECDKLRTNTTAVGISKPANIHVKSPCSVV 720
Query: 721 GNSNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGIT 780
GNSNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGIT
Sbjct: 721 GNSNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTLSVKGIT 780
Query: 781 PAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQ 840
PAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQ
Sbjct: 781 PAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQ 840
Query: 841 NESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVE 900
NESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVE
Sbjct: 841 NESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVE 900
Query: 901 GDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPV 960
GDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPV
Sbjct: 901 GDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPV 960
Query: 961 QCTDVSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDI 1020
QCTDVSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDI
Sbjct: 961 QCTDVSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDI 1020
Query: 1021 YPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQT 1080
YPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQT
Sbjct: 1021 YPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQT 1080
Query: 1081 TYQTSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPI 1140
TYQTSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPI
Sbjct: 1081 TYQTSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPI 1140
Query: 1141 TEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEE 1200
TEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEE
Sbjct: 1141 TEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEE 1200
Query: 1201 EKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTP 1260
EKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTP
Sbjct: 1201 EKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTP 1260
Query: 1261 KTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQE 1320
KTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQE
Sbjct: 1261 KTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQE 1320
Query: 1321 TRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQG 1380
TRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQG
Sbjct: 1321 TRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQG 1380
Query: 1381 NVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKF 1440
NVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKF
Sbjct: 1381 NVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKF 1440
Query: 1441 SRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSS 1500
SRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSS
Sbjct: 1441 SRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSS 1500
Query: 1501 GVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTN 1560
GVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTN
Sbjct: 1501 GVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTN 1560
Query: 1561 ISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTF 1620
ISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTF
Sbjct: 1561 ISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTF 1620
Query: 1621 LPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLK 1680
LPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLK
Sbjct: 1621 LPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLK 1680
Query: 1681 FVATKKRTQKDSQERDNVNSRLSKRSFSADGFEMLQNPVKDSKEMFQTYKQMYLEKRSRS 1740
FVATKKRTQKDSQERDNVNSRLSKRSFSADGFEMLQNPVKDSKEMFQTYKQMYLEKRSRS
Sbjct: 1681 FVATKKRTQKDSQERDNVNSRLSKRSFSADGFEMLQNPVKDSKEMFQTYKQMYLEKRSRS 1740
Query: 1741 LGSSPVK 1747
LGSSPVK
Sbjct: 1741 LGSSPVK 1747
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 58.2 bits (139), Expect = 7e-08
Identities = 147/798 (18%), Positives = 320/798 (40%), Gaps = 117/798 (14%)
Query: 971 DQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQE---IDA 1027
+Q S + +N +T+ +K + T+ ST + S ED+ +E D+
Sbjct: 212 NQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTS-----EDMADKEKSTADS 266
Query: 1028 SSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSED 1087
P E PV E +K + + V Q+++ Q ++
Sbjct: 267 GGEGLETAPKSEEFSDLPCPV--------EEIKNYTKEHNNLILLNKDVQQESSEQKNKS 318
Query: 1088 QTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQC 1147
+ DS + ++ + +E+ + + +D V D+ +KE
Sbjct: 319 TDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVE-------- 370
Query: 1148 DLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNS--SSEEEKQKE 1205
L+ P+ S + ++ K+D + +G+ +S+ S SS EE +E
Sbjct: 371 SLKLPSEKNSNKAKTVEGTKEDFSL-----IDSDVDGLTDITVSSVHTSDLSSFEEDTEE 425
Query: 1206 QCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKHK 1265
+ + ++S ++GE TSD + K+ N KT + D S T +H
Sbjct: 426 EV--VTSDSMEEGEITSDDEE-----KNKQNKTKT---------QTSDSSEGKTKSVRHA 469
Query: 1266 SLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKK 1325
+ + L + +S D+L Q + E + + E+ ++ +QK
Sbjct: 470 YVHKPY--LYSKYYSDSDDELTVEQRRQSIAKEKEERLL----RRQINREKLEEKRKQKA 523
Query: 1326 HVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKL---------KSVSFKQKRK 1376
T++S KTK + D+ S +SL P+ ++K K V+ +KRK
Sbjct: 524 EKTKSS---KTKGQGRSSVDL---EESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRK 577
Query: 1377 LDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSN--TKSVDTK 1434
D NV + KK+++++ ++ T K + KEK+ S+ K V K
Sbjct: 578 KDSRNVEENSKKKQQYEEDSKE-----TLKTSEHCE--------KEKISSSKELKHVHAK 624
Query: 1435 ASSSKFSRILTPKEYLQRQKHKEALSNKASKK-----ICVKNVPCDSEHMRPSKLAVQVE 1489
+ SK +R L+ ++ + E+ + K+ + ++ V +++ + + E
Sbjct: 625 SEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSE 684
Query: 1490 SCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIW 1549
C + +K S ++ K+LK S+ ++L+ + K ++P++
Sbjct: 685 ICTEEPQKQKSTLKNE-----------KHLKKDDSETPHLKSLLKK-EVKSSKEKPER-- 730
Query: 1550 IDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTE--RESISLTKLESSPRKL 1607
+KT + ++ ++ + M + D+ +L+ + G K E ++ TKL S +
Sbjct: 731 -EKTPSEDKLSVKHKYKGDCM-HKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTE 788
Query: 1608 HKDKRQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQ 1667
K K + + + L G + E+ + D ++ N+ +ER+ + E +
Sbjct: 789 RKSKHRNERKLSVLGKDGKP----VSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRR 844
Query: 1668 VSGIKSTKEDW---LKFVATKKRTQKDSQERDNVNSRLSKRSFSADGFEMLQNPVKDSKE 1724
S K K+ + ++R++ S+++ +++S + + E++ + +K
Sbjct: 845 SSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPE--EVVHKEKRRTKS 902
Query: 1725 MFQTYKQMYLEKRSRSLG 1742
+ + +++ L+ +S++ G
Sbjct: 903 LLE--EKLVLKSKSKTQG 918
Score = 50.1 bits (118), Expect = 2e-05
Identities = 179/991 (18%), Positives = 354/991 (35%), Gaps = 140/991 (14%)
Query: 795 GSVCSLQNQLAENAKATAALKVDVSGPVASTATST-KIFPLTQKEKQNESTNGNSEVTPN 853
G ++ N + +L + S AST TS K K+ ++ T S
Sbjct: 192 GPSANVANDAMSILETITSLNQEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKER 251
Query: 854 VNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIF 913
++ +K +S S + + +S + + +I N K
Sbjct: 252 TSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNY--------------TKEH 297
Query: 914 SSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQS 973
++L L + Q+ S Q+ + + EK+ D+ + + +K+K + D S K D
Sbjct: 298 NNLILLNKDVQQES-SEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQ 356
Query: 974 KSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTP 1033
K + ++ +E+ ++ EK+S + T + T D + ++D ++ T
Sbjct: 357 KVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDF--------SLIDSDVDGLTDITV 408
Query: 1034 QDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSEDQTADKT 1093
+++ S + D E+ + + + EG + + +++T +T
Sbjct: 409 SSVHTSDLSS------FEEDTEEEV-------VTSDSMEEGEITSDDEEKNKQNKTKTQT 455
Query: 1094 SSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDK----LAEPQKEEPITEVVSQCDL 1149
S S+ ++ + + + D V++ +A+ ++E + +++ L
Sbjct: 456 SDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKL 515
Query: 1150 Q------------APAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSS 1197
+ + GQ R SV L+ + V + + ++
Sbjct: 516 EEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLK-----ERKVLEKKV 570
Query: 1198 SEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRK 1257
+ +K+K+ ++ NS K+ + D T L + + S EL+ K
Sbjct: 571 ALSKKRKKDSRNVEENSKKKQQYEEDSKET------LKTSEHCEKEKISSSKELKHVHAK 624
Query: 1258 DTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLR-------FHEVTFHSSNKM 1310
P + L + + + SK ++ HKR+ E +
Sbjct: 625 SEPSKPARRLSESLHVVDENKNESKLER-----EHKRRTSTPVIMEGVQEETDTRDVKRQ 679
Query: 1311 TASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLK-SV 1369
E ++E +++K +N + LK + P+ K PE+ K + +
Sbjct: 680 VERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKL 739
Query: 1370 SFKQKRKLD----QGNVLDMEVKKK------KHDKQEQKGSVGATFKLGDSLSNPNERAI 1419
S K K K D G+ ++ +K KQ Q+ + + K + NER +
Sbjct: 740 SVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKL 799
Query: 1420 VKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHM 1479
SV K I+ E ++++ +NK +++ + + +
Sbjct: 800 ----------SVLGKDGKPVSEYIIKTDENVRKE------NNKKERRLSAEKTKAEHKSR 843
Query: 1480 RPSKLAVQVESCGKSNEKHSSGVQTSKESLN------GLTSHGKNLK---IHHSQESKTY 1530
R S +Q +S G +++H +Q ES + T+ NLK + H ++ +T
Sbjct: 844 RSSDSKIQKDSLG--SKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTK 901
Query: 1531 NILR-----NVKEKVGGKQPDKIWID----------KTKLDKLTNISNEAQFSQMPPQVK 1575
++L K K GKQ + + K DK N Q +V+
Sbjct: 902 SLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVE 961
Query: 1576 DQKKLYLNRVGFKCTERESISLTKLESSPR---KLHKDKRQENKHKTFLPVK---GNTEK 1629
D+ T S T+ +SS R L K+K + +K T ++ + K
Sbjct: 962 DKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHK 1021
Query: 1630 SNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQ 1689
S L+ DI K+ N +++ + E+A G S E L + R
Sbjct: 1022 SRSLKHS-SKDIKKKDENKSDDKDGKEVDSSHEKA----RGNSSLMEKKLSRRLCENRRG 1076
Query: 1690 KDSQERDNVNSRLSKRSFSADGFEMLQNPVK 1720
SQE +L+ + S LQ P K
Sbjct: 1077 SLSQEMAKGEEKLAANTLSTPSGSSLQRPKK 1107
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 54.3 bits (129), Expect = 1e-06
Identities = 114/568 (20%), Positives = 220/568 (38%), Gaps = 91/568 (16%)
Query: 1197 SSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSR 1256
+ EE Q S +D N + +++D + + K ++ + P + DD
Sbjct: 291 TDSEEAQSVNPSSVDENI----DSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDE 346
Query: 1257 KDTPKTKHKSLPRTEQ------ELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKM 1310
+ + + R EQ E +K +K ++ K KK + V + S+
Sbjct: 347 EINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSST--- 403
Query: 1311 TASYEQASQETRQKKHVTQNSRPL-KTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSV 1369
E + +E Q K ++ + + +T + + K K++ G+ K+K KLK+
Sbjct: 404 ----ESSDEEALQNKKISTSCSVIPETSNSDMQTK---KEYVVSGEHKQKGKVKRKLKN- 455
Query: 1370 SFKQKRKLDQGNVLDMEVKKKKH-------------DKQEQKGSVGATFKLGDSLS---- 1412
+ K K +Q + E K+ +K ++G+ +F D S
Sbjct: 456 --QNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLF 513
Query: 1413 ------NPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHKEA--LSNKAS 1464
+P + EK + K TK S S ++ + L R + E+ L +S
Sbjct: 514 HISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSS 573
Query: 1465 KKICVKNVPCDSEHMRPSKLAVQVESCGK-SNEKHSSGVQTSKESLNGLTSHGKNLKIH- 1522
K C S+H + L +S K +E HS + S +L + GK LK H
Sbjct: 574 VKSCKHKEK--SKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHK 631
Query: 1523 --HSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKL 1580
H + K ++ KE G K+ K +L + E + + + + + L
Sbjct: 632 LKHKEREKE----KHKKEIEGEKEKYKTKDSAKELQRSVEFDREF-WKENFFKSDETEDL 686
Query: 1581 YLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKH----KTFLPVKGNTEKSNMLEFK 1636
+LN E ES++L K + + DK + KH + F + +K + F+
Sbjct: 687 FLNM------EHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFR 740
Query: 1637 LCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKST--------------KEDWLKFV 1682
+ +K+ EER+++ E L +S I+ + +E +K
Sbjct: 741 ---EEKIKDLK--EERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIK-- 793
Query: 1683 ATKKRTQKDSQERDNVNSRLSKRSFSAD 1710
+K++ +K SQ ++ ++ +++F +
Sbjct: 794 ESKEKPEKRSQIKEKDIEKMERKTFEKE 821
Score = 37.4 bits (85), Expect = 0.13
Identities = 62/261 (23%), Positives = 108/261 (41%), Gaps = 42/261 (16%)
Query: 1189 QCNSIKNSSSEEEKQKEQCSPLDTNSCKQGER----TSDRDVTVVQFKSLVNNPKTPPDG 1244
Q ++ + S SE+ K KE+ LD + + T+ + + + S+V+ K +
Sbjct: 914 QSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEK 973
Query: 1245 KSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTF 1304
E D TP K K +++ ++ + + +Q + KL+
Sbjct: 974 PLSLKEKTKDEPLKTPDGKEKD----KKDKDIDRYKERDKHKDKIQINSLLKLK------ 1023
Query: 1305 HSSNKMTASYEQASQETRQKKHVTQNSRPLKTK-TAFLPNKDV-----YKKHSSLGQSLS 1358
++K AS++TR K+ N ++T L KD+ +KKH
Sbjct: 1024 SEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHK------- 1076
Query: 1359 PEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERA 1418
EKIK K +K +L N L++++K +K + + +L S S+ A
Sbjct: 1077 -EKIKQK-------EKERLRNRNCLELKIK--DKEKTKHTPTESKNKELTRSKSSEVTDA 1126
Query: 1419 IVKEKM----VSN-TKSVDTK 1434
KEK VSN ++SVDTK
Sbjct: 1127 YTKEKQPKDAVSNRSQSVDTK 1147
Score = 33.5 bits (75), Expect = 1.9
Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Query: 213 PPPKLYRYSPQSFL-PDSTIQKQNFIPHTSLQVKNSQLPNSVLTLPSRQTSAVPSQQYAT 271
P +L S + F+ P+S I Q + +N L + L RQT +P A
Sbjct: 1399 PVDRLETLSTRDFICPNSNIPDQESSLQSFCNSENKVLKENADFLSLRQTE-LPGNSCA- 1456
Query: 272 QTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSRE 310
Q PP C + SQ L + I+KH+S+ ++E
Sbjct: 1457 QDPASFMPPQQPCSFPSQSLSDAESISKHMSLSYVANQE 1495
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 54.3 bits (129), Expect = 1e-06
Identities = 114/568 (20%), Positives = 220/568 (38%), Gaps = 91/568 (16%)
Query: 1197 SSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSR 1256
+ EE Q S +D N + +++D + + K ++ + P + DD
Sbjct: 314 TDSEEAQSVNPSSVDENI----DSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDE 369
Query: 1257 KDTPKTKHKSLPRTEQ------ELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKM 1310
+ + + R EQ E +K +K ++ K KK + V + S+
Sbjct: 370 EINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSST--- 426
Query: 1311 TASYEQASQETRQKKHVTQNSRPL-KTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSV 1369
E + +E Q K ++ + + +T + + K K++ G+ K+K KLK+
Sbjct: 427 ----ESSDEEALQNKKISTSCSVIPETSNSDMQTK---KEYVVSGEHKQKGKVKRKLKN- 478
Query: 1370 SFKQKRKLDQGNVLDMEVKKKKH-------------DKQEQKGSVGATFKLGDSLS---- 1412
+ K K +Q + E K+ +K ++G+ +F D S
Sbjct: 479 --QNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLF 536
Query: 1413 ------NPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHKEA--LSNKAS 1464
+P + EK + K TK S S ++ + L R + E+ L +S
Sbjct: 537 HISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSS 596
Query: 1465 KKICVKNVPCDSEHMRPSKLAVQVESCGK-SNEKHSSGVQTSKESLNGLTSHGKNLKIH- 1522
K C S+H + L +S K +E HS + S +L + GK LK H
Sbjct: 597 VKSCKHKEK--SKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHK 654
Query: 1523 --HSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKL 1580
H + K ++ KE G K+ K +L + E + + + + + L
Sbjct: 655 LKHKEREKE----KHKKEIEGEKEKYKTKDSAKELQRSVEFDREF-WKENFFKSDETEDL 709
Query: 1581 YLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKH----KTFLPVKGNTEKSNMLEFK 1636
+LN E ES++L K + + DK + KH + F + +K + F+
Sbjct: 710 FLNM------EHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFR 763
Query: 1637 LCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKST--------------KEDWLKFV 1682
+ +K+ EER+++ E L +S I+ + +E +K
Sbjct: 764 ---EEKIKDLK--EERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIK-- 816
Query: 1683 ATKKRTQKDSQERDNVNSRLSKRSFSAD 1710
+K++ +K SQ ++ ++ +++F +
Sbjct: 817 ESKEKPEKRSQIKEKDIEKMERKTFEKE 844
Score = 37.4 bits (85), Expect = 0.13
Identities = 62/261 (23%), Positives = 108/261 (41%), Gaps = 42/261 (16%)
Query: 1189 QCNSIKNSSSEEEKQKEQCSPLDTNSCKQGER----TSDRDVTVVQFKSLVNNPKTPPDG 1244
Q ++ + S SE+ K KE+ LD + + T+ + + + S+V+ K +
Sbjct: 937 QSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEK 996
Query: 1245 KSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTF 1304
E D TP K K +++ ++ + + +Q + KL+
Sbjct: 997 PLSLKEKTKDEPLKTPDGKEKD----KKDKDIDRYKERDKHKDKIQINSLLKLK------ 1046
Query: 1305 HSSNKMTASYEQASQETRQKKHVTQNSRPLKTK-TAFLPNKDV-----YKKHSSLGQSLS 1358
++K AS++TR K+ N ++T L KD+ +KKH
Sbjct: 1047 SEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHK------- 1099
Query: 1359 PEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERA 1418
EKIK K +K +L N L++++K +K + + +L S S+ A
Sbjct: 1100 -EKIKQK-------EKERLRNRNCLELKIK--DKEKTKHTPTESKNKELTRSKSSEVTDA 1149
Query: 1419 IVKEKM----VSN-TKSVDTK 1434
KEK VSN ++SVDTK
Sbjct: 1150 YTKEKQPKDAVSNRSQSVDTK 1170
Score = 33.5 bits (75), Expect = 1.9
Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Query: 213 PPPKLYRYSPQSFL-PDSTIQKQNFIPHTSLQVKNSQLPNSVLTLPSRQTSAVPSQQYAT 271
P +L S + F+ P+S I Q + +N L + L RQT +P A
Sbjct: 1422 PVDRLETLSTRDFICPNSNIPDQESSLQSFCNSENKVLKENADFLSLRQTE-LPGNSCA- 1479
Query: 272 QTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSRE 310
Q PP C + SQ L + I+KH+S+ ++E
Sbjct: 1480 QDPASFMPPQQPCSFPSQSLSDAESISKHMSLSYVANQE 1518
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 53.1 bits (126), Expect = 2e-06
Identities = 90/435 (20%), Positives = 167/435 (38%), Gaps = 46/435 (10%)
Query: 1196 SSSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDS 1255
SS E E+ K+ S +TN Q +T ++ + K N+ KT + F +++
Sbjct: 165 SSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKT----NTEFLHTKNNP 220
Query: 1256 RKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEV--TFHSSNKMTAS 1313
+KD ++K + P +E + + S D L + + + F + +N S
Sbjct: 221 KKDLKRSKTSNDPISE---ICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYS 277
Query: 1314 YEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQ 1373
+ + K + S +++ + KD K ++ + + +K +S +
Sbjct: 278 LKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAES 337
Query: 1374 KRKLDQGNVLDMEVKKKKHD---KQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKS 1430
D+ + KK K D K +K + GD+ N+ +K+ ++ K
Sbjct: 338 GDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKK 397
Query: 1431 VDTK--ASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKN----VPCDSEHMRPSKL 1484
D K S+ L KE Q+ + K+ +K K VKN DSE SK
Sbjct: 398 KDAKKITFSTDSESELESKES-QKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKK 456
Query: 1485 AVQVESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQ 1544
+ E GK + K + +K++ T +L++ + ++ KEK G K+
Sbjct: 457 GKKDEKKGKKDSKKDDKKKDAKKNAES-TEMESDLELKKDK--------KHSKEKKGSKK 507
Query: 1545 PDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSP 1604
D K + S +A+F + ++ GFK + + S T+ E S
Sbjct: 508 ------DIKKDARKDTESTDAEFDES------------SKTGFKTSTKIKGSDTESEESL 549
Query: 1605 RKLHKDKRQENKHKT 1619
K K+ + T
Sbjct: 550 YKPGAKKKIDESDGT 564
Score = 40.4 bits (93), Expect = 0.015
Identities = 76/363 (20%), Positives = 145/363 (39%), Gaps = 44/363 (12%)
Query: 1386 EVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRILT 1445
E KK K +K + K G +NP + IV+EK ++ T SS + +
Sbjct: 114 EYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE-QS 172
Query: 1446 PKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLA-VQVESCGKSNEKHSSGVQT 1504
K + + E+ ++K K C + DS++ + + + ++ K + K S +T
Sbjct: 173 KKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRS---KT 229
Query: 1505 SKESLNGLTSHGK----NLKIHHSQESKTYNI---LRNVKEKVGGKQPDKIWIDKTKLDK 1557
S + ++ + S L + + ++ N LRN + K + TK D
Sbjct: 230 SNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQN-NSKNYSLKYTKYTKKDT 288
Query: 1558 LTNI--SNEAQFSQMPPQVKDQKKLYLN--RVGFKCTERESISLTKLES----------- 1602
N S++A+ KD KK+ N + K ++ T ES
Sbjct: 289 KKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTK 348
Query: 1603 -SPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRK 1661
+KL KD ++++ K P +TE + + + L K + + +++KD K
Sbjct: 349 KDKKKLKKDDKKKDTKK--YPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFS 406
Query: 1662 EQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQERDNVNSRLSKRSFSADGFEMLQNPVKD 1721
+ ++ +S K++ K+ +KDS+ + + + + S AD P D
Sbjct: 407 TDSESELESKESQKDE--------KKDKKDSKTDNKKSVKNDEESTDAD-----SEPKGD 453
Query: 1722 SKE 1724
SK+
Sbjct: 454 SKK 456
Score = 35.4 bits (80), Expect = 0.49
Identities = 53/280 (18%), Positives = 104/280 (37%), Gaps = 40/280 (14%)
Query: 1440 FSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHM-RPSKLAVQVESCGKSNEKH 1498
F + T K +L++ ++K++ K + + + P + E + NE
Sbjct: 100 FRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEAD 159
Query: 1499 SSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDK----------- 1547
+ +++S E+ S + SQ SKT + + K+K K K
Sbjct: 160 KTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNN 219
Query: 1548 ----IWIDKTKLDKLTNISNE----AQFSQMPPQVKDQK---KLYLNRVGFKCTERESIS 1596
+ KT D ++ I +E F + Q D+ +L ++ S+
Sbjct: 220 PKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLK 279
Query: 1597 LTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVK 1656
TK K + K + + + K +++K + KN +++KDVK
Sbjct: 280 YTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKK------------VKKNVKKDDKKKDVK 327
Query: 1657 PHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQERD 1696
E + K ++D K KK+ +KD +++D
Sbjct: 328 KD--TESTDAESGDSKDERKDTKK---DKKKLKKDDKKKD 362
Score = 33.5 bits (75), Expect = 1.9
Identities = 59/309 (19%), Positives = 105/309 (33%), Gaps = 40/309 (12%)
Query: 1193 IKNSSSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPEL- 1251
+K + +++K+K+ ++ + G+ +R T K L + K K +PE
Sbjct: 313 VKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKK--YPEST 370
Query: 1252 ----------------------QDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPL 1289
DD +KD K + +E E Q K DK +
Sbjct: 371 DTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSK 430
Query: 1290 QNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKK 1349
++K+ E T S S + E + KK ++ + KD K
Sbjct: 431 TDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDK----------KKDAKKN 480
Query: 1350 HSSLGQSLSPEKIKLKLKSVSFK-QKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLG 1408
S E K K S K K+ + + D E + D+ + G +T G
Sbjct: 481 AESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKG 540
Query: 1409 DSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKIC 1468
+E ++ K D +++SK + + + + R K+ N+ +K
Sbjct: 541 S--DTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRGF--RMSSKKTTFNEKGEKAS 596
Query: 1469 VKNVPCDSE 1477
VP E
Sbjct: 597 TGRVPPSRE 605
Score = 32.3 bits (72), Expect = 4.1
Identities = 48/206 (23%), Positives = 87/206 (42%), Gaps = 15/206 (7%)
Query: 441 SKLSLKQTAKIQSGPQITPVMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRRFNQV 500
SK +++ K Q+ TP+ + Q+ S+ETN NS NC + ++
Sbjct: 144 SKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPES--QNSKTVSKNCSQKDKK 201
Query: 501 DSVLPNPVYSE-KRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSPAVC 559
DS +E +P D+K SKTS +++ L+ + + V Q+
Sbjct: 202 DSKNSKKTNTEFLHTKNNPKKDLK--RSKTSNDPISEICSENSLNVDFLMLVGQSDD--- 256
Query: 560 ETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQDS---KPDSCEM 616
E+I+ + S+ ++N L + T+K K ++ +DS K DS ++
Sbjct: 257 ESINFDAWLRN---YSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKV 313
Query: 617 NPNTQMTGNQLNLKNMETPSTSNVSG 642
N + + ++K +T ST SG
Sbjct: 314 KKNVKKDDKKKDVKK-DTESTDAESG 338
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 50.1 bits (118), Expect = 2e-05
Identities = 151/806 (18%), Positives = 305/806 (37%), Gaps = 118/806 (14%)
Query: 986 LETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIY--PQEIDASSNYTPQDPARNEIHS 1043
+ N+ I++K T + A+D S A ++E + P +S ++ P+ +I +
Sbjct: 1115 ISENQAIIQKL----ITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPE--LEEKILA 1168
Query: 1044 DKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTSE----DQTADKTSSDSKD 1099
+ L +L E L ++ +E + ++ Q + + D+ S ++++
Sbjct: 1169 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENEN 1228
Query: 1100 PADQI-QITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQSR 1158
DQ+ Q+ I E + P D Q + P EEP+ + Q Q +S
Sbjct: 1229 IGDQLRQLQIQVRESIDGKLPSTDQQESCS---STPGLEEPLFKATEQHHTQPVL--ESN 1283
Query: 1159 DSVILDSEKDDIHCCALGW-LSMVYEGVPQCQCNSIK------NSSSEEEKQKEQCSPLD 1211
S +D G ++ + + + + ++ +++SE K+ E+ L
Sbjct: 1284 LCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQ 1343
Query: 1212 TNSCKQGER-------TSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTKH 1264
KQG + + +V + + + + G H ELQ PK
Sbjct: 1344 EQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQ-------PKLDE 1396
Query: 1265 --KSLPRTEQEL--VAGQFSSKCDKLNPLQN------------HKRKKLRFHEVTFHSSN 1308
K + + E+++ ++GQ S K L +Q H + +++ E
Sbjct: 1397 LQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQ 1456
Query: 1309 ------KMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKI 1362
+M E+ +E+R K+ + + K + A + K+ K++ SL + LS +
Sbjct: 1457 LQVELCEMKQKPEEIGEESRAKQQIQR-----KLQAALISRKEALKENKSLQEELSLARG 1511
Query: 1363 KLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKE 1422
++ + S ++ +V + +K G + + D L +R++++
Sbjct: 1512 TIERLTKSLAD---------VESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN 1562
Query: 1423 KMVSNT---------------KSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKI 1467
+ +S++ + + + S K S+I E+ ++KHKE
Sbjct: 1563 QSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEW--QEKHKELQKEYEILLQ 1620
Query: 1468 CVKNVPCDSEHMRPSKLAVQVES---CGKSNEKHSSGVQTSKESLNGLTSHGKNLK--IH 1522
+NV ++E ++ AV+ E GK ++ +T K+ L + +K +
Sbjct: 1621 SYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQ-LQEAEQEMEEMKEKMR 1679
Query: 1523 HSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYL 1582
+SK IL +E + D K T +S+ A + +VK + +
Sbjct: 1680 KFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLS 1739
Query: 1583 NRVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCPDIL 1642
+ +E++S+S ++ Q+ KH+ ++GN K LE D
Sbjct: 1740 KKFQSLMSEKDSLS-------------EEVQDLKHQ----IEGNVSKQANLEATEKHD-- 1780
Query: 1643 LKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQERDNVNSRL 1702
TN EE P +EQ L +S + E + KD D +N+ L
Sbjct: 1781 -NQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYL 1839
Query: 1703 SKRSFSADGFEMLQNPVKDSKEMFQT 1728
+ + L+ + +KE QT
Sbjct: 1840 QQIDQLKERIAGLEEEKQKNKEFSQT 1865
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 49.7 bits (117), Expect = 3e-05
Identities = 119/553 (21%), Positives = 210/553 (37%), Gaps = 116/553 (20%)
Query: 1189 QCNSIKNSSSEEEKQKEQCSPLDTNSCKQG----ERTSDRDVTVVQF-KSLVNNPKTPPD 1243
+C +++ E ++ + + S N KQ E T R T Q +S PK D
Sbjct: 660 ECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSD 719
Query: 1244 GKSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVT 1303
G P+ + D R +TPK K +S P T ++ G+ + P H ++
Sbjct: 720 GHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPET------PKHRHDNRR------- 766
Query: 1304 FHSSNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIK 1363
S K S E+ + ++ K+ +S LK++ A E +K
Sbjct: 767 --DSGK--PSTEKKPEVSKHKQDTKSDSPRLKSERA--------------------EALK 802
Query: 1364 LKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEK 1423
+ S + + D N K+K D+ E + G R E
Sbjct: 803 QRPDGRSVSESLRRDHDN------KQKSDDRGESERHRG-----------DQSRVRRPET 845
Query: 1424 MVSNTKSV-DTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEH-MRP 1481
+ S++++ K+ SSK ++ +KH+ + + P E RP
Sbjct: 846 LRSSSRNEHGIKSDSSKTDKL--------ERKHRHESGDSRER-------PSSGEQKSRP 890
Query: 1482 SKLAVQVESCGKS-NEKHSSGVQTSKES--LNGLTSHGKNLKIHHSQESKTYNILRNVKE 1538
V+ KS ++K TSK+ G S K H +++ + L
Sbjct: 891 DSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYL----- 945
Query: 1539 KVGGKQP--DKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLY-----LNRVGFKCTE 1591
+GG+ I K K DK N++ E + +M + KD+ + LN+
Sbjct: 946 -LGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVV 1004
Query: 1592 RESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEF------KLCPDILLKN 1645
+ +SL ++ KL KD R++ + P+K KSN +L P++L +
Sbjct: 1005 LQKLSLDDVQ----KLIKD-REDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEI 1059
Query: 1646 TNSVEERKDVKPHPRKEQAP------LQVSGIKSTKEDWLKFVATKKRTQKDS------Q 1693
+++ + VK + RK ++S + D F +++KR +KD +
Sbjct: 1060 ESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSD-EAFESSRKRHKKDDDKAWEYE 1118
Query: 1694 ERDNVNSRLSKRS 1706
ERD +S +RS
Sbjct: 1119 ERDRRSSGDHRRS 1131
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 49.7 bits (117), Expect = 3e-05
Identities = 119/553 (21%), Positives = 210/553 (37%), Gaps = 116/553 (20%)
Query: 1189 QCNSIKNSSSEEEKQKEQCSPLDTNSCKQG----ERTSDRDVTVVQF-KSLVNNPKTPPD 1243
+C +++ E ++ + + S N KQ E T R T Q +S PK D
Sbjct: 660 ECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSD 719
Query: 1244 GKSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVT 1303
G P+ + D R +TPK K +S P T ++ G+ + P H ++
Sbjct: 720 GHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPET------PKHRHDNRR------- 766
Query: 1304 FHSSNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIK 1363
S K S E+ + ++ K+ +S LK++ A E +K
Sbjct: 767 --DSGK--PSTEKKPEVSKHKQDTKSDSPRLKSERA--------------------EALK 802
Query: 1364 LKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEK 1423
+ S + + D N K+K D+ E + G R E
Sbjct: 803 QRPDGRSVSESLRRDHDN------KQKSDDRGESERHRG-----------DQSRVRRPET 845
Query: 1424 MVSNTKSV-DTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEH-MRP 1481
+ S++++ K+ SSK ++ +KH+ + + P E RP
Sbjct: 846 LRSSSRNEHGIKSDSSKTDKL--------ERKHRHESGDSRER-------PSSGEQKSRP 890
Query: 1482 SKLAVQVESCGKS-NEKHSSGVQTSKES--LNGLTSHGKNLKIHHSQESKTYNILRNVKE 1538
V+ KS ++K TSK+ G S K H +++ + L
Sbjct: 891 DSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYL----- 945
Query: 1539 KVGGKQP--DKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLY-----LNRVGFKCTE 1591
+GG+ I K K DK N++ E + +M + KD+ + LN+
Sbjct: 946 -LGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVV 1004
Query: 1592 RESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEF------KLCPDILLKN 1645
+ +SL ++ KL KD R++ + P+K KSN +L P++L +
Sbjct: 1005 LQKLSLDDVQ----KLIKD-REDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEI 1059
Query: 1646 TNSVEERKDVKPHPRKEQAP------LQVSGIKSTKEDWLKFVATKKRTQKDS------Q 1693
+++ + VK + RK ++S + D F +++KR +KD +
Sbjct: 1060 ESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSD-EAFESSRKRHKKDDDKAWEYE 1118
Query: 1694 ERDNVNSRLSKRS 1706
ERD +S +RS
Sbjct: 1119 ERDRRSSGDHRRS 1131
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 49.3 bits (116), Expect = 3e-05
Identities = 139/729 (19%), Positives = 285/729 (39%), Gaps = 135/729 (18%)
Query: 1087 DQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQ--PYVVDKLAEPQKEEPITEVV 1144
D +A+ S + + ++ Q + +QMK++F ++ Q + D ++ +E + E
Sbjct: 132 DSSAELQSLEQQ--LEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAA 189
Query: 1145 SQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQC---NSIKNSSSEEE 1201
Q + +VI D + + + + ++++ + + Q Q N E E
Sbjct: 190 EQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESE 249
Query: 1202 KQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPK 1261
K K++C L + + + + T+ Q +S + K P + + ELQ + +
Sbjct: 250 KLKDECKKLQS-------QYASSEATISQLRSEL--AKGPQEVAVYVQELQK-LKSSVNE 299
Query: 1262 TKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLR----------------------- 1298
K+ TE L Q +K ++ + ++ +K ++
Sbjct: 300 LTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETS 359
Query: 1299 FHEVTFHSSNKMTASY---EQASQETRQKKHVT------QNSRPLKTKTAFLPNKDVYKK 1349
H + S K A+ E+ S+ + +H+ Q R K + ++ +
Sbjct: 360 LHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQL 419
Query: 1350 HSSLGQS----------------LSPEKI----------KLKLKSVSFKQKRKLDQGNVL 1383
HS L ++ LS EK+ +LKL + + K K+ L
Sbjct: 420 HSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTEL 479
Query: 1384 DMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSKFSRI 1443
++ K K QEQ+ +T K + N + K +I
Sbjct: 480 QHQLDKTKQQHQEQQALQQST--------------TAKLREAQNDLEQVLRQIGDKDQKI 525
Query: 1444 LTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSSGVQ 1503
+ LQ+ K +L K + + K + E ++L EK+
Sbjct: 526 QNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQL----------QEKN----H 571
Query: 1504 TSKESLNGLTSHGKNLKIHHSQ-ESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNIS 1562
T +E + LT KN H Q + ++ ++ K + Q D++ +T +++L +
Sbjct: 572 TLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQ-DRVLSLETSVNELNSQL 630
Query: 1563 NEA--QFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTF 1620
NE+ + SQ+ Q+K + +L L+ K +R + L+++ L +++ NK T
Sbjct: 631 NESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQ-NHLDTAQNALQDKQQELNKITTQ 689
Query: 1621 L-----PVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSG-IKST 1674
L ++ E + LE + ++E K+ + EQ ++ G IK
Sbjct: 690 LDQVTAKLQDKQEHCSQLE------------SHLKEYKE--KYLSLEQKTEELEGQIKKL 735
Query: 1675 KEDWLKFVATKKRTQKDSQERDNVNSRLSKRSFSADGFEMLQNPVKDSKEMFQTYKQMYL 1734
+ D L+ A+K++ +D Q++ +N+ L R+ L ++ KE+ + ++ L
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLELRATE------LSKQLEMEKEIVSS-TRLDL 788
Query: 1735 EKRSRSLGS 1743
+K+S +L S
Sbjct: 789 QKKSEALES 797
Score = 42.0 bits (97), Expect = 0.005
Identities = 91/476 (19%), Positives = 199/476 (41%), Gaps = 49/476 (10%)
Query: 1191 NSIKNSSSEEEK--QKEQCSPLD-TNSCKQ--GERTSDRDVTVVQFKSLVNNPKTPPDGK 1245
+S+KNS SE EK QK + + LD +CK+ + + T+ + K L + + +
Sbjct: 867 DSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEA- 925
Query: 1246 SHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFH 1305
SH +L+ +S ++ +L + E+E Q ++L K+K++ +
Sbjct: 926 SHQLKLELNSMQEQLIQAQNTLKQNEKE--EQQLQGNINELKQSSEQKKKQIEALQ---- 979
Query: 1306 SSNKMTASYEQASQETRQKKHVTQNSRPL---KTKTAFLPNKDVYKKHSSLGQSLSPEKI 1362
A ++ E + ++ +TQ ++ L K K + L N Y+K
Sbjct: 980 -GELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNN--YEKSQE---------- 1026
Query: 1363 KLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKE 1422
+FKQ + G ++ ++ E+K S+ + + N+ +++E
Sbjct: 1027 -------TFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQE 1079
Query: 1423 -KMVSNTKSVDTKASSSKFSRILTPKEYLQRQK--HKEALSNKASKKICVKNVPCDSEHM 1479
K T D+ + + +Q++K ++ L N+ SK ++ + C E
Sbjct: 1080 LKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQE-K 1138
Query: 1480 RPSKLAVQVESCGKSNEKHSSGVQTSKESL--NGLTSHGK--NLKIHHSQESKTYNILRN 1535
+KL +++S + K + ++ +K+ L L GK +LK QE + IL++
Sbjct: 1139 EITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKD 1198
Query: 1536 VKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESI 1595
+K ++ + K ++K + +E + ++ + ++ + L E
Sbjct: 1199 QVKK------EEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGT 1252
Query: 1596 SLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEE 1651
+ +SS R++ + ++Q + + + V T ++N E + + LK +E+
Sbjct: 1253 VKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEK 1308
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 47.4 bits (111), Expect = 1e-04
Identities = 91/408 (22%), Positives = 166/408 (40%), Gaps = 76/408 (18%)
Query: 1329 QNSRPLKTKTAFLPNKDVYKKHS-----SLGQSLSPEKIKLK-----LKSVSFKQKRKLD 1378
+N R L K L N+ V +K S +L + L EK +L+ L+ S +Q + L+
Sbjct: 499 ENQR-LSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE 557
Query: 1379 QGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSS 1438
Q N E + Q+ + A ++ D E I+ E + K +SS
Sbjct: 558 QEN----EHLNQTVSSLRQRSQISAEARVKDI---EKENKILHESI---------KETSS 601
Query: 1439 KFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNE-- 1496
K S+I E+ +RQ KE K + R +L ++ K NE
Sbjct: 602 KLSKI----EFEKRQIKKELEHYKEKGE-------------RAEELENELHHLEKENELL 644
Query: 1497 -KHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWIDKTKL 1555
K + ++ + E + L L+ + + KT + +N+ ++ + + +D+ L
Sbjct: 645 QKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENL 704
Query: 1556 DKLTNISN----EAQFSQMPPQVKD--------QKKLYLNRVGFKCTERESISLTKLESS 1603
+ N+ + + +Q+ + K+ +K L L + FK TER +S L+
Sbjct: 705 ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIE 764
Query: 1604 PRKLHKDKRQENK-------HKTFLPVKGNTEKSNMLEFKLCP---DILLKNTNSVEE-- 1651
++L K NK L ++ T + N+ E K+ + L K S+E+
Sbjct: 765 NQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQET 824
Query: 1652 ---RKDVKPHPRKEQAPLQVSGIKST--KEDWLKFVATKKRTQKDSQE 1694
KD K ++ + Q + IK T +E+ +K +K + S+E
Sbjct: 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Score = 35.0 bits (79), Expect = 0.64
Identities = 92/530 (17%), Positives = 212/530 (40%), Gaps = 84/530 (15%)
Query: 1247 HFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHS 1306
H + DDSR ++K +S + E+ K +K+ L+ + +++
Sbjct: 944 HDEQSTDDSRYKLLESKLESTLKKSLEI-------KEEKIAALEARLEESTNYNQQLRQE 996
Query: 1307 SNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKL 1366
+ +YE A ++ + ++ + Q+S P+ + K Q + E +K+K
Sbjct: 997 LKTVKKNYE-ALKQRQDEERMVQSSPPISGED---------NKWERESQETTRELLKVKD 1046
Query: 1367 KSVSFKQKRKLDQGN--VLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPN---ERAIVK 1421
+ + ++ Q L ++K+ + + + A + SL N + K
Sbjct: 1047 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAK 1106
Query: 1422 EKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRP 1481
++ ++T + + + ++ +++L + L+ + ++ + + K ++ D E +
Sbjct: 1107 LQVENSTLNSQSTSLMNQNAQLLIQQSSLENE-NESVIKEREDLKSLYDSLIKDHEKLE- 1164
Query: 1482 SKLAVQVESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVG 1541
+E+ +S ++ L S KNL++ H YN L K ++
Sbjct: 1165 -----------LLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLE 1213
Query: 1542 G-KQPDKIWIDKTKLDKLTNISNEAQFSQMPPQ-----------VKDQKKLYLNRVGFKC 1589
++ K+ +K L+ + + A++ ++ + +K+ + L + K
Sbjct: 1214 DLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKS 1273
Query: 1590 TERES-ISLTKLESSPRKLHKDKRQ--------ENKHKTFLPVKGNTEKSNMLEFKLCPD 1640
S + T+LE+ KL + +Q N+ + +KGN E+ N
Sbjct: 1274 LLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQT 1333
Query: 1641 ILLKNTNSVEERKDVKP--HPRKEQAPLQVSGIKSTKE---------------------- 1676
++L+N +E+ + K H + Q +++ ++ KE
Sbjct: 1334 LMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRG 1393
Query: 1677 DWLKFVATKK-RTQKD-SQERDNVNSRLSKRSFSADGFEMLQNPVKDSKE 1724
+W+ K +++KD ++ER + RS S++GF LQ P +DS++
Sbjct: 1394 NWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGF--LQLPHQDSQD 1441
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 47.4 bits (111), Expect = 1e-04
Identities = 91/408 (22%), Positives = 166/408 (40%), Gaps = 76/408 (18%)
Query: 1329 QNSRPLKTKTAFLPNKDVYKKHS-----SLGQSLSPEKIKLK-----LKSVSFKQKRKLD 1378
+N R L K L N+ V +K S +L + L EK +L+ L+ S +Q + L+
Sbjct: 499 ENQR-LSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE 557
Query: 1379 QGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSS 1438
Q N E + Q+ + A ++ D E I+ E + K +SS
Sbjct: 558 QEN----EHLNQTVSSLRQRSQISAEARVKDI---EKENKILHESI---------KETSS 601
Query: 1439 KFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNE-- 1496
K S+I E+ +RQ KE K + R +L ++ K NE
Sbjct: 602 KLSKI----EFEKRQIKKELEHYKEKGE-------------RAEELENELHHLEKENELL 644
Query: 1497 -KHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWIDKTKL 1555
K + ++ + E + L L+ + + KT + +N+ ++ + + +D+ L
Sbjct: 645 QKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENL 704
Query: 1556 DKLTNISN----EAQFSQMPPQVKD--------QKKLYLNRVGFKCTERESISLTKLESS 1603
+ N+ + + +Q+ + K+ +K L L + FK TER +S L+
Sbjct: 705 ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIE 764
Query: 1604 PRKLHKDKRQENK-------HKTFLPVKGNTEKSNMLEFKLCP---DILLKNTNSVEE-- 1651
++L K NK L ++ T + N+ E K+ + L K S+E+
Sbjct: 765 NQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQET 824
Query: 1652 ---RKDVKPHPRKEQAPLQVSGIKST--KEDWLKFVATKKRTQKDSQE 1694
KD K ++ + Q + IK T +E+ +K +K + S+E
Sbjct: 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Score = 36.2 bits (82), Expect = 0.29
Identities = 185/991 (18%), Positives = 374/991 (37%), Gaps = 189/991 (19%)
Query: 836 QKEKQNESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNI 895
Q EK E+ NSE + + ++ L + S QIS E+R + + +
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----- 591
Query: 896 CSLVEGDTSYNSQIAKI-FSSLPLKM-VEPQKPSLPNQQGIGSREPEKQLDNTTENKDFG 953
L E +S+++KI F +K +E K ++G + E E +L + + +
Sbjct: 592 --LHESIKETSSKLSKIEFEKRQIKKELEHYK-----EKGERAEELENELHHLEKENELL 644
Query: 954 FQKDKPVQCTDVSHKICDQSKSEPPLES--------SFNNLETNRVILEKSSLEHATEKS 1005
+K ++ T + +Q SE E+ SF NL LEK + + E
Sbjct: 645 QKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENL 704
Query: 1006 TANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYG 1065
S AS E+ S+K +QL + L+
Sbjct: 705 ELRRNVESLKC----------ASMKMAQLQLENKELESEK-------EQLKKGLELLKAS 747
Query: 1066 IEAVNTREGSVGQQTTYQ--TSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDD 1123
+ E S YQ E+Q KT +S Q++ + E + + +
Sbjct: 748 FKKTERLEVS------YQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Query: 1124 QPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYE 1183
+ + K E ++E L+ + +D L+ E +
Sbjct: 802 ELKISSKRLEQLEKE-------NKSLEQETSQLEKDKKQLEKENKRLR------------ 842
Query: 1184 GVPQCQCNSIKNSSSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPD 1243
Q IK+++ EE K + ++ +T +++ + + +S V + +
Sbjct: 843 -----QQAEIKDTTLEENNVK-------IGNLEKENKTLSKEIGIYK-ESCVRLKELEKE 889
Query: 1244 GKSHFPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVT 1303
K EL + D K+L ++LV+ +KL Q + + HE+
Sbjct: 890 NK----ELVKRATIDI-----KTLVTLREDLVS-------EKLKTQQMNNDLEKLTHELE 933
Query: 1304 FHSSNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLS-PEKI 1362
NK +++ S + R K ++ LK K+ + + + + L +S + +++
Sbjct: 934 KIGLNKERLLHDEQSTDDRYKLLESKLESTLK-KSLEIKEEKIAALEARLEESTNYNQQL 992
Query: 1363 KLKLKSVSFKQ---KRKLDQGNVLDMEVKKKKHDKQEQKGSVGAT---FKLGDSLSNP-- 1414
+ +LK+V K++ D+ ++ D + ++ S T K+ D L
Sbjct: 993 RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVER 1052
Query: 1415 NERAIVKEKMVSNT--KSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNV 1472
N + EK T K ++T+ ++ + + ++ + Q+ L + + K+ V+N
Sbjct: 1053 NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ-NAKLQVENS 1111
Query: 1473 PCDSEHM----RPSKLAVQVESCGKSNE---KHSSGVQTSKESL---------------- 1509
+S+ + ++L +Q S NE K +++ +SL
Sbjct: 1112 TLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQAS 1171
Query: 1510 ---NGLTSHG------KNLKIHHSQESKTYNILRNVKEKVGG-KQPDKIWIDKTKLDKLT 1559
+ ++ HG KNL++ H YN L K ++ ++ K+ +K L+
Sbjct: 1172 EYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKN 1231
Query: 1560 NISNEAQFSQMPPQ-----------VKDQKKLYLNRVGFKCTERES-ISLTKLESSPRKL 1607
+ + A++ ++ + +K+ + L + K S + T+LE+ KL
Sbjct: 1232 HETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKL 1291
Query: 1608 HKDKRQ--------ENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKP-- 1657
+ +Q N+ + +KGN E+ N ++L+N +E+ + K
Sbjct: 1292 KEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLF 1351
Query: 1658 HPRKEQAPLQVSGIKSTKE----------------------DWLKFVATKK-RTQKD-SQ 1693
H + Q +++ ++ KE +W+ K +++KD ++
Sbjct: 1352 HVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINR 1411
Query: 1694 ERDNVNSRLSKRSFSADGFEMLQNPVKDSKE 1724
ER + RS S++GF LQ P +DS++
Sbjct: 1412 ERQKSLTLTPTRSDSSEGF--LQLPHQDSQD 1440
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 46.6 bits (109), Expect = 2e-04
Identities = 101/525 (19%), Positives = 192/525 (36%), Gaps = 96/525 (18%)
Query: 1194 KNSSSEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPK---TPPDGKSHFPE 1250
K + E +++ +C+P ++ R VT K P+ TP +S
Sbjct: 297 KERKNRERERERECNPPNSQPASYQRRLL---VTRSGRKIKGRGPRRYRTPSRSRSR--- 350
Query: 1251 LQDDSRKDTPKTKHKSLPRTEQELVA-GQFSSKCDK--LNPLQNHKRKKLRFHEVTFHSS 1307
R +TP + + R ++ V+ G+ K DK LN ++ ++R +R E
Sbjct: 351 -DRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDH 409
Query: 1308 NKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLK 1367
++ S + +++ ++ K NS+ + + K +S S K K K K
Sbjct: 410 RNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSK 469
Query: 1368 SVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSN 1427
S K ++ + K + H+ ++K K DS ER+ KEK
Sbjct: 470 SKERDSKHNRNEEKRMRSRSKGRDHENVKEKE------KQSDSKGKDQERSRSKEK---- 519
Query: 1428 TKSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQ 1487
+K +++K++ S+ ++K + A S
Sbjct: 520 SKQLESKSNEHDHSK--------SKEKDRRAQSRS------------------------- 546
Query: 1488 VESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIH--HSQESKTYNILRNVKEKVGGKQP 1545
C + KHS +T + S + S + H SK Y+ R + + G+
Sbjct: 547 -RECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGR-- 603
Query: 1546 DKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPR 1605
+ ++ + PP K R + +ERE ES R
Sbjct: 604 -----------------SRSRERRTPPGRSRSKDRRRRRRDSRSSERE-------ESQSR 639
Query: 1606 KLHKDKRQENK--HKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVKPHPRKEQ 1663
K + QE+K H+ K N+E + K N+ + +D P + +Q
Sbjct: 640 NKDKYRNQESKSSHR-----KENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQ 694
Query: 1664 A----PLQVSGIKSTKEDWLKFVATKKRTQKDSQERDNVNSRLSK 1704
+ L+ S +K+ +++ ++ K+ + QE D+V+ + K
Sbjct: 695 SSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKK 739
>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
Length = 1486
Score = 45.8 bits (107), Expect = 4e-04
Identities = 154/832 (18%), Positives = 283/832 (34%), Gaps = 102/832 (12%)
Query: 17 PKSQPPFLHQSLINQITTTSQSSFSYPGSNQEACMYPGNSNPISQPLLNIQNYPQQISVS 76
P +Q P + +TTT + + + S P + P++ + P +S +
Sbjct: 161 PVTQKPVTTVTSTYSMTTTEKGTSAMTSS-------PSTTTARETPIVTVT--PSSVSAT 211
Query: 77 DMHNGTVVASHTSVERITYANVNGPKQLTHNLQMSSGVTQNVWLNSPMRNPVHSHIGATV 136
D T ++S T T T + + + V SP+ + + S T
Sbjct: 212 DTTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTS 271
Query: 137 SHQTDFGANVPNMPALQSQLITSDTYSMQMQMIPSNSTRLPVAYQGNQGLNQSFSEQQVD 196
T N + ++ I S T + + I S T L+ +
Sbjct: 272 MTTTASQPTATNTLSSPTRTILSSTPVLSTETITSGITN-------TTPLSTLVTTLPTT 324
Query: 197 WTQQCISKGLTYPDYRPPPKLYRYSPQSFLPDSTIQKQNFIPHTSLQVKNSQLPNSVLTL 256
++ + TYP SP S + DST + T + LP + +L
Sbjct: 325 ISRSTPTSETTYPT----------SPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSL 374
Query: 257 PSRQTSAVPSQQYATQTDKRPPPPPYNCRYGSQPLQSTQHITKHLSMEVPQSREMLSSEI 316
P+ +T+ P T T + + + S + ST +T H S +S I
Sbjct: 375 PTTETATTPMTNLVTTTTEISSHSTPS--FSSSTIYST--VTSH-------STPRFTSSI 423
Query: 317 RTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPFNSPIRSS-VDGVQTLAQTNEEKIMDS 375
T+ P S FTN K ++ F S I ++ T + T+ ++
Sbjct: 424 TTTETPSHSTPRFTSS----FTNTKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTET 479
Query: 376 CNPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSELARKIKINKDLLMAAGCIKMTNTSYS 435
+ ++ + E + ++ S + + + TS+S
Sbjct: 480 TSHSARSFTSSITTTETTSHNTRSFTS-----SITTTETNSHSTTSFTSSITTTETTSHS 534
Query: 436 EPAQNSKLSLKQTAKIQSGPQITP--VMPENAERQTPTVVESAETNKTQCMLNSDIQEVN 493
P+ +S ++ +T + S P +T + TP + S T +T
Sbjct: 535 TPSFSSSITTTET-PLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGF---- 589
Query: 494 CRRFNQVDSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQ 553
S+ SE P + +S + T + T ++S T
Sbjct: 590 ------TSSITTTETTSESTP-----------SLSSSTIYSTVSTSTTAITSHFTT---- 628
Query: 554 NSPAVCETISVPKSMSTEEYKSKIQNENMLLLALLSQARKTQKTVLKDANQTIQD----- 608
+ AV T P S+ST+ I ++ L S T T D D
Sbjct: 629 SETAVTPTPVTPSSLSTD-----IPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLP 683
Query: 609 SKPDSCEMNPNTQMT-GNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTKGMPAKSDSS 667
++ +P+ Q T + L T ST ++ R+ +N+ S +S +P ++
Sbjct: 684 TRTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIP---ETP 740
Query: 668 CSMEVLATCLSLWKKQPSDT-----AKEKECDKLRTNTTAVGISKPANIHVKSPCSVVGN 722
+ T + + P+ T + + L T T + +S + + P +
Sbjct: 741 TQTPPVLTSATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTS-QVPIPSTHS 799
Query: 723 SNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLSEVKTL------SV 776
S Q S PS QT+L+ S + T + S ++ S T+ S
Sbjct: 800 STLQTTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSS 859
Query: 777 KGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATS 828
ITP V T++ V + S +N + + +L + +ST++S
Sbjct: 860 ASITP-VFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSS 910
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 44.7 bits (104), Expect = 8e-04
Identities = 145/765 (18%), Positives = 264/765 (34%), Gaps = 121/765 (15%)
Query: 919 KMVEPQKPSLPNQQGIGSREPEKQLDNTTENK-----DFGFQKDKPVQCTDVSH------ 967
K V+ +K + ++ E K LDN E + + G KD +S
Sbjct: 1082 KDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEI 1141
Query: 968 -KICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQE-I 1025
K + K EP E E +++ L + + + T S+ I P E +
Sbjct: 1142 VKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKL 1201
Query: 1026 DASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTS 1085
+++S+ Q+ + ++ L + G V E ++T + +
Sbjct: 1202 ESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSE----EKTDTKRT 1257
Query: 1086 EDQTADKTSSDSKDPADQ--IQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEV 1143
+T ++ ++D+ PA+ I I + S+ K+ F +++ ++ K + +
Sbjct: 1258 VIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKN 1317
Query: 1144 VSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQ 1203
VS +++ EK E P + S E Q
Sbjct: 1318 VST----------KPSNIVKYPEK---------------ESEPSEKIQKFTKDVSHEIIQ 1352
Query: 1204 KEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTK 1263
E S ++ S ++G +T DRD +V++ ++ PE + +S T K
Sbjct: 1353 HEVKSSKNSASSEKG-KTKDRDYSVLEKEN---------------PEKRKNS---TQPEK 1393
Query: 1264 HKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQ 1323
+L R ++ G F S + + H+ T SSNK +
Sbjct: 1394 ESNLDRLNEQ---GNFKSLSQSSKEARTSDK-----HDSTRASSNKDFTPNRDKKTDYDT 1445
Query: 1324 KKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVL 1383
+++ + R K + + K S+ GQ P +++R L +
Sbjct: 1446 REYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKP------------REERDLPKKGTG 1493
Query: 1384 DMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNE--RAIVKEKMVSNTKSV-----DTKAS 1436
D + + + AT+ PNE +++ K K V + ++S
Sbjct: 1494 DSKKSNSSPSRDRKPHDHKATY----DTKRPNEETKSVDKNPCKDREKHVLEARNNKESS 1549
Query: 1437 SSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMR-PSKLAVQVESCGKS- 1494
+K IL P E Q KE ++ + K VK P S R S L + +
Sbjct: 1550 GNKLLYILNPPE---TQVEKEQITGQIDKST-VKPKPQLSHSSRLSSDLTRETDEAAFEP 1605
Query: 1495 --NEKHS-SGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWID 1551
NE S S V +E +G S K+LK I+ KE + ++ I
Sbjct: 1606 DYNESDSESNVSVKEEESSGNIS--KDLKD---------KIVEKAKESLDTAAVVQVGIS 1654
Query: 1552 KTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPRKLHKDK 1611
+ + ++S S Q + + S K + +K HK
Sbjct: 1655 RNQSHSSPSVSPSRSHSPSGSQTRSHSSS-------ASSAESQDSKKKKKKKEKKKHKKH 1707
Query: 1612 RQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVK 1656
++ KHK + EKS + K K+ +E+ D K
Sbjct: 1708 KKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1752
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 44.7 bits (104), Expect = 8e-04
Identities = 145/765 (18%), Positives = 264/765 (34%), Gaps = 121/765 (15%)
Query: 919 KMVEPQKPSLPNQQGIGSREPEKQLDNTTENK-----DFGFQKDKPVQCTDVSH------ 967
K V+ +K + ++ E K LDN E + + G KD +S
Sbjct: 1116 KDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEI 1175
Query: 968 -KICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQE-I 1025
K + K EP E E +++ L + + + T S+ I P E +
Sbjct: 1176 VKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKL 1235
Query: 1026 DASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTS 1085
+++S+ Q+ + ++ L + G V E ++T + +
Sbjct: 1236 ESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSE----EKTDTKRT 1291
Query: 1086 EDQTADKTSSDSKDPADQ--IQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEV 1143
+T ++ ++D+ PA+ I I + S+ K+ F +++ ++ K + +
Sbjct: 1292 VIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKN 1351
Query: 1144 VSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQ 1203
VS +++ EK E P + S E Q
Sbjct: 1352 VST----------KPSNIVKYPEK---------------ESEPSEKIQKFTKDVSHEIIQ 1386
Query: 1204 KEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKTK 1263
E S ++ S ++G +T DRD +V++ ++ PE + +S T K
Sbjct: 1387 HEVKSSKNSASSEKG-KTKDRDYSVLEKEN---------------PEKRKNS---TQPEK 1427
Query: 1264 HKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQETRQ 1323
+L R ++ G F S + + H+ T SSNK +
Sbjct: 1428 ESNLDRLNEQ---GNFKSLSQSSKEARTSDK-----HDSTRASSNKDFTPNRDKKTDYDT 1479
Query: 1324 KKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGNVL 1383
+++ + R K + + K S+ GQ P +++R L +
Sbjct: 1480 REYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKP------------REERDLPKKGTG 1527
Query: 1384 DMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNE--RAIVKEKMVSNTKSV-----DTKAS 1436
D + + + AT+ PNE +++ K K V + ++S
Sbjct: 1528 DSKKSNSSPSRDRKPHDHKATY----DTKRPNEETKSVDKNPCKDREKHVLEARNNKESS 1583
Query: 1437 SSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMR-PSKLAVQVESCGKS- 1494
+K IL P E Q KE ++ + K VK P S R S L + +
Sbjct: 1584 GNKLLYILNPPE---TQVEKEQITGQIDKST-VKPKPQLSHSSRLSSDLTRETDEAAFEP 1639
Query: 1495 --NEKHS-SGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQPDKIWID 1551
NE S S V +E +G S K+LK I+ KE + ++ I
Sbjct: 1640 DYNESDSESNVSVKEEESSGNIS--KDLKD---------KIVEKAKESLDTAAVVQVGIS 1688
Query: 1552 KTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESISLTKLESSPRKLHKDK 1611
+ + ++S S Q + + S K + +K HK
Sbjct: 1689 RNQSHSSPSVSPSRSHSPSGSQTRSHSSS-------ASSAESQDSKKKKKKKEKKKHKKH 1741
Query: 1612 RQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKDVK 1656
++ KHK + EKS + K K+ +E+ D K
Sbjct: 1742 KKHKKHKKHAGTEVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQK 1786
>gi|148613886 regulatory factor X domain containing 2 [Homo sapiens]
Length = 1460
Score = 44.3 bits (103), Expect = 0.001
Identities = 60/256 (23%), Positives = 104/256 (40%), Gaps = 35/256 (13%)
Query: 705 ISKPAN---IHVKSPCSVVGNSNSQNKISNPSQQTALSMVMHNYESSGINITKGTELQIA 761
+ KPAN + ++SP +V+ S+ +TA+ H S +N+ K T + +
Sbjct: 433 LPKPANTSALTIRSPTTVLFTSSPI--------KTAVVPASH---MSSLNVVKMTTISLT 481
Query: 762 VVS---PLVLSEVKTLSVKGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDV 818
+ PL S SV T P IK GSV SLQ+ + ++ A V+V
Sbjct: 482 PSNSNTPLKHSA----SVSSATGTTEESRSVPQIKNGSVVSLQSPGSRSSSAGGTSAVEV 537
Query: 819 SGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPNVNQGKHNKLESAIHSPMNDQQISQE 878
TS+ P+ +E +E+ + TP+ G+ + + A+ P N+ I E
Sbjct: 538 K---VEPETSSDEHPVQCQENSDEA---KAPQTPSALLGQKSNTDGALQKPSNEGVI--E 589
Query: 879 SRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIG--- 935
+ + V T ++ G ++ N+Q S + S PN I
Sbjct: 590 IKATKVCDQRTKCKSRCNEMLPGTSTGNNQSTITLSVASQNLTFTSSSSPPNGDSINKDP 649
Query: 936 ---SREPEKQLDNTTE 948
++ P K+L +T +
Sbjct: 650 KLCTKSPRKRLSSTLQ 665
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 43.9 bits (102), Expect = 0.001
Identities = 176/982 (17%), Positives = 364/982 (37%), Gaps = 133/982 (13%)
Query: 794 EGSVCSLQNQLAENAKATAALKVDVSGPVASTATSTKIFPLTQKEKQNESTNGNSEVTPN 853
EG + LQ +L + + AL+ +V + K P ++ E+ + SE
Sbjct: 719 EGKITDLQKELNKEVEENEALREEVI-----LLSELKSLP-SEVERLRKEIQDKSEELHI 772
Query: 854 VNQGKHNKLESAIHSPMNDQQISQESRNSTVVSSDTLQIDNICSLVEGDTSYNSQIAKIF 913
+ K +H Q + +E + L ++Y S +
Sbjct: 773 ITSEKDKLFSEVVHKESRVQGLLEEIGKTKD------------DLATTQSNYKSTDQEFQ 820
Query: 914 SSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTTENKDFGFQKDKPVQCTDVSHKICDQS 973
+ L M QK + ++ + L + D K T++S+K +
Sbjct: 821 NFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALK----TELSYKTQELQ 876
Query: 974 KSEPPLESSFNNLETNRVILEKSSLEHAT---EKSTANDTCSSAAIQEDIYPQEID---- 1026
+ ++ N +E + LE T EK+ + + QE D
Sbjct: 877 EKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQ 936
Query: 1027 -ASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQQTTYQTS 1085
S +D +++IH + +QL L+ E +NT + + + + S
Sbjct: 937 LQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISE----EVS 992
Query: 1086 EDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVS 1145
+ ++ + ++KD Q + I +Q E Q V D Q+ + + +
Sbjct: 993 RNLHMEENTGETKDEFQQKMVGI-DKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQE 1051
Query: 1146 QCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQKE 1205
+ +LQ Q +SVI +EK+ + + M E + ++ E +KQ+E
Sbjct: 1052 KNELQ-----QMLESVI--AEKEQLKTDLKENIEMTIENQEE-----LRLLGDELKKQQE 1099
Query: 1206 QCSPLDTNSC-KQGE--RTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPKT 1262
+ ++ K+GE RT DR V ++ K
Sbjct: 1100 IVAQEKNHAIKKEGELSRTCDRLAEV----------------------------EEKLKE 1131
Query: 1263 KHKSLPRTEQEL--VAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHS--------SNKMTA 1312
K + L +Q+L V + S K+N ++N K +L+ E+T + K+
Sbjct: 1132 KSQQLQEKQQQLLNVQEEMSEMQKKINEIENLK-NELKNKELTLEHMETERLELAQKLNE 1190
Query: 1313 SYEQASQETRQKKHVTQNSRPLKTKTAFLPN--KDVYKKHSSLGQSLSPEKIKLKLKSVS 1370
+YE+ T+++K + + + +T+ L +++ + L I LK +
Sbjct: 1191 NYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQET 1250
Query: 1371 FKQKRKL---DQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSN 1427
+ R+ +++ + +K H K +++ + + + L N E + +E M N
Sbjct: 1251 IDELRRSVSEKTAQIINTQDLEKSHTKLQEE--IPVLHEEQELLPNVKEVSETQETM--N 1306
Query: 1428 TKSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQ 1487
+ T+ S++K S L E ++R + E + +K++ + ++++ K A++
Sbjct: 1307 ELELLTEQSTTKDSTTLARIE-MERLRLNEKFQESQEE---IKSLTKERDNLKTIKEALE 1362
Query: 1488 V------ESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQES---KTYNILRNVKE 1538
V E ++ K ++SLN + KI E K +LR E
Sbjct: 1363 VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIE 1422
Query: 1539 KVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQV----KDQKKLYLNRVGFKCTERES 1594
+G + + D++ +++ E Q +V DQ K + + K E E
Sbjct: 1423 MLGLSKR-----LQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEE 1477
Query: 1595 ISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCPDILLKNTNSVEERKD 1654
+L+ + L + + N+ + L K + + + D L + E+++
Sbjct: 1478 ----ELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEE 1533
Query: 1655 VKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQERDNVNSRLSKRSFSADGFEM 1714
+ + +V+ +K KE R KDS + + L + + E
Sbjct: 1534 QFNIKQISEVQEKVNELKQFKE---------HRKAKDSALQSIESKMLELTNRLQESQEE 1584
Query: 1715 LQNPVKDSKEMFQTYKQMYLEK 1736
+Q +K+ +EM + + + +E+
Sbjct: 1585 IQIMIKEKEEMKRVQEALQIER 1606
Score = 35.4 bits (80), Expect = 0.49
Identities = 47/253 (18%), Positives = 96/253 (37%), Gaps = 12/253 (4%)
Query: 291 LQSTQHITKHLSMEVPQSREMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQPF 350
L+ Q++ H+ + E I+T FQQ N E + + N + + +
Sbjct: 2229 LKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDI---EKL 2285
Query: 351 NSPIRSSVDGVQTLAQTNEEKIMDSCNPTSNQVLDTSVAKEKLVRDIKTLVEIKQKFSEL 410
+ I+ D + + +I+ N ++ ++ ++ +D+K+L K+K +L
Sbjct: 2286 KNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSL---KEKNEKL 2342
Query: 411 ARKIKINKDLLMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITPVMPENAERQTP 470
+ + K L + + T P S+ + T KI+ E+A +
Sbjct: 2343 FKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKES 2402
Query: 471 TVV----ESAETNKTQCMLNSDIQEVN--CRRFNQVDSVLPNPVYSEKRPMPDPSHDVKV 524
++ E TN L + + E N + + VL + V +P + D+K+
Sbjct: 2403 KIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKM 2462
Query: 525 LTSKTSAVEMTQA 537
K +M A
Sbjct: 2463 KLVKIDLEKMKNA 2475
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.1 bits (100), Expect = 0.002
Identities = 97/502 (19%), Positives = 196/502 (39%), Gaps = 79/502 (15%)
Query: 1261 KTKHKSLPRTEQELVAGQ-----FSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYE 1315
+T++ SL + Q+L A Q F+S ++L + + K K++ E + A+ E
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE 828
Query: 1316 QASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKR 1375
+ Q+ +Q+ +K + N + K Q LS I K++ + K
Sbjct: 829 KTVQDLKQE---------IKALKEEIGNVQLEK-----AQQLS---ITSKVQELQNLLKG 871
Query: 1376 KLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNE--RAIVKEKMVSNTKSVDT 1433
K +Q N + +++K+ D + T K L NE +A V+E N K +
Sbjct: 872 KEEQMNTMKAVLEEKEKD-------LANTGKWLQDLQEENESLKAHVQEVAQHNLKEASS 924
Query: 1434 KASSSKFSRILTPKEYLQRQKH---KEALSNKASKKICVKNVPCDSEHMRPSKLAVQVES 1490
+ + +L KE ++ KE S+ +SK +++V +++ + Q+E
Sbjct: 925 ASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKS-----QIEQ 979
Query: 1491 CGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQP----- 1545
+ N + +S +E L ++ K + S +N L ++K+ V ++
Sbjct: 980 LKQQNYQQASSFPPHEELLKVISEREKEI-------SGLWNELDSLKDAVEHQRKKNNDL 1032
Query: 1546 -DKIW--------IDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRV----------- 1585
+K W +K DK+ S E Q Q V+ + K L ++
Sbjct: 1033 REKNWEAMEALASTEKMLQDKVNKTSKERQ--QQVEAVELEAKEVLKKLFPKVSVPSNLS 1090
Query: 1586 ------GFKCTERESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCP 1639
GF+ +E ++ T + L ++ ++ T L ++ KS + E +
Sbjct: 1091 YGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGIL 1150
Query: 1640 DILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQERDNVN 1699
L ++ E + VK + S S++++ + + K + +ER+++
Sbjct: 1151 QKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLE 1210
Query: 1700 SRLSKRSFSADGFEMLQNPVKD 1721
L K + +KD
Sbjct: 1211 MELEKAEMERSTYVTEVRELKD 1232
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.1 bits (100), Expect = 0.002
Identities = 97/502 (19%), Positives = 196/502 (39%), Gaps = 79/502 (15%)
Query: 1261 KTKHKSLPRTEQELVAGQ-----FSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYE 1315
+T++ SL + Q+L A Q F+S ++L + + K K++ E + A+ E
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE 828
Query: 1316 QASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKR 1375
+ Q+ +Q+ +K + N + K Q LS I K++ + K
Sbjct: 829 KTVQDLKQE---------IKALKEEIGNVQLEK-----AQQLS---ITSKVQELQNLLKG 871
Query: 1376 KLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNE--RAIVKEKMVSNTKSVDT 1433
K +Q N + +++K+ D + T K L NE +A V+E N K +
Sbjct: 872 KEEQMNTMKAVLEEKEKD-------LANTGKWLQDLQEENESLKAHVQEVAQHNLKEASS 924
Query: 1434 KASSSKFSRILTPKEYLQRQKH---KEALSNKASKKICVKNVPCDSEHMRPSKLAVQVES 1490
+ + +L KE ++ KE S+ +SK +++V +++ + Q+E
Sbjct: 925 ASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKS-----QIEQ 979
Query: 1491 CGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGGKQP----- 1545
+ N + +S +E L ++ K + S +N L ++K+ V ++
Sbjct: 980 LKQQNYQQASSFPPHEELLKVISEREKEI-------SGLWNELDSLKDAVEHQRKKNNDL 1032
Query: 1546 -DKIW--------IDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRV----------- 1585
+K W +K DK+ S E Q Q V+ + K L ++
Sbjct: 1033 REKNWEAMEALASTEKMLQDKVNKTSKERQ--QQVEAVELEAKEVLKKLFPKVSVPSNLS 1090
Query: 1586 ------GFKCTERESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLCP 1639
GF+ +E ++ T + L ++ ++ T L ++ KS + E +
Sbjct: 1091 YGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGIL 1150
Query: 1640 DILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQERDNVN 1699
L ++ E + VK + S S++++ + + K + +ER+++
Sbjct: 1151 QKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLE 1210
Query: 1700 SRLSKRSFSADGFEMLQNPVKD 1721
L K + +KD
Sbjct: 1211 MELEKAEMERSTYVTEVRELKD 1232
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 43.1 bits (100), Expect = 0.002
Identities = 87/389 (22%), Positives = 149/389 (38%), Gaps = 79/389 (20%)
Query: 818 VSGPVASTATSTKIFPLTQKEKQNEST------------------NG---NSEVTPNVN- 855
V GP+ + T TK F L + KQ E T NG + V PN
Sbjct: 399 VKGPLCKSVTPTKEF-LKDEIKQEEETCKRISTITALGHEGKQLVNGEVSDERVAPNFKT 457
Query: 856 ---QGKHNKLESAIHSPMNDQQI-----SQESRNSTVVSSDTLQIDNICSLVEGDTSYNS 907
+ K + + +SP D+ I ES NS + S T +++ + + D +
Sbjct: 458 EPIETKFYETKEESYSPSKDRNIITEGNGTESLNSVITSMKTGELEKETAPLRKDADSSI 517
Query: 908 QIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLDNTT------------ENKDFGFQ 955
+ +I S ++ EP P + + + S E K L + T E K +
Sbjct: 518 SVLEIHSQ-KAQIEEPDPPEM--ETSLDSSEMAKDLSSKTALSSTESCTMKGEEKSPKTK 574
Query: 956 KDKPVQCTDVSHKICDQSK----------SEPPLESSFNNLETNRVILEKSSLEHATEKS 1005
KDK + K+ K S P E + LE+ EK A E S
Sbjct: 575 KDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLES-----EKPGSPEAAETS 629
Query: 1006 TAN---DTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEF 1062
+ D C A ++++ E ++S Q + ++ + K + ++ L
Sbjct: 630 PPSNIIDHCEKLASEKEVV--ECQSTSTVGGQSVKKVDLETLKEDSEFTKVEMDNLDNAQ 687
Query: 1063 PYGIEAVNTREGSVGQQTTYQ-----TSEDQTADKTSSDSKDPADQIQITILSSEQMKEI 1117
GIE + +GS+ Q++ ++ E ++ T S+ + I++TI S + K
Sbjct: 688 TSGIEEPSETKGSM-QKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKK-- 744
Query: 1118 FPEQDDQPYVVD---KLAEPQKEEPITEV 1143
+ D P V++ K + +KEE T V
Sbjct: 745 --KPDSPPKVLEPENKQEKTEKEEEKTNV 771
Score = 41.6 bits (96), Expect = 0.007
Identities = 44/211 (20%), Positives = 88/211 (41%), Gaps = 13/211 (6%)
Query: 1309 KMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYK----------KHSSLGQSLS 1358
K + + + + + P +TK + +K YK +++ +
Sbjct: 670 KEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQ 729
Query: 1359 PEKIKLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERA 1418
E IKL ++ +S ++K+ VL+ E K++K +K+E+K +VG T + +S P +
Sbjct: 730 KEGIKLTIR-ISSRKKKPDSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPRISRPTAKV 788
Query: 1419 IVKEKMVSNTKSVDTKASSSKFSRIL--TPKEYLQRQKHKEALSNKASKKICVKNVPCDS 1476
++ K + + + S L T K+ + ++ K+ S + K K S
Sbjct: 789 AEIRDQKADKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKVRWTGS 848
Query: 1477 EHMRPSKLAVQVESCGKSNEKHSSGVQTSKE 1507
K + ES G +EK S+ + +E
Sbjct: 849 RTRGRWKYSSNDESEGSGSEKSSAASEEEEE 879
Score = 36.6 bits (83), Expect = 0.22
Identities = 76/390 (19%), Positives = 150/390 (38%), Gaps = 52/390 (13%)
Query: 980 ESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDPARN 1039
E S++ + +I E + E T+ T ++++ P DA S+ +
Sbjct: 469 EESYSPSKDRNIITEGNGTESLNSVITSMKT---GELEKETAPLRKDADSSISVL----- 520
Query: 1040 EIHSDKA-------PVLYLHDQLSELLKEFPYGIEAVNTREGSV-GQQTTYQTSED---- 1087
EIHS KA P + SE+ K+ +T ++ G++ + +T +D
Sbjct: 521 EIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKGEEKSPKTKKDKRPP 580
Query: 1088 --------QTADKTSSD------SKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAE 1133
+ + KT D S P + + T+ S + E ++D +
Sbjct: 581 ILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLESEKPGSPEAAETSPPSNIIDHCEK 640
Query: 1134 PQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSI 1193
E+ + E C + GQS V L++ K+D + + + + Q + I
Sbjct: 641 LASEKEVVE----CQSTSTVGGQSVKKVDLETLKEDSE-----FTKVEMDNLDNAQTSGI 691
Query: 1194 KNSSS-----EEEKQKEQCSPLD-TNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSH 1247
+ S ++ K K + P + T + + E TS+R ++ +++ K PD
Sbjct: 692 EEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKPDSPPK 751
Query: 1248 FPELQDDSRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSS 1307
E ++ K + + ++ RT + + + S K+ +++ K K R E
Sbjct: 752 VLEPENKQEKTEKEEEKTNVGRTLRR--SPRISRPTAKVAEIRDQKADKKR-GEGEDEVE 808
Query: 1308 NKMTASYEQASQETRQKKHVTQNSRPLKTK 1337
+ TA + +E +K NS+ K K
Sbjct: 809 EESTALQKTDKKEILKKSEKDTNSKVSKVK 838
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 41.6 bits (96), Expect = 0.007
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 47/388 (12%)
Query: 289 QPLQSTQHITKHLSMEVPQSREMLSSEIRTSFQQQWQNPNENVSTIGNFTNLKVNTNSKQ 348
+ LQS + + +EV +++ M+ E+ Q+ Q E+ +T+ L+V ++
Sbjct: 1076 ETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEK 1135
Query: 349 PFNSPIRSSVDGVQTLAQTNEEKIMDSCNPTSNQVLDTSVAK-EKLVRDI-KTLVEIKQK 406
+ L +T +E + + +++ +A E+L++++ + L K
Sbjct: 1136 -------------KQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNK 1182
Query: 407 FSELARKIKINKD----LLMAAGCIKMTNTSYSEPAQNSKLSLKQTAKIQSGPQITP--- 459
+L ++IKI K L ++ + Y E K L +T K + +
Sbjct: 1183 IEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDH 1242
Query: 460 -VMPENAERQTPTVVESAETNKTQCMLNSDIQEVNCRRFNQVDSVLPNPVYSEKRPMPDP 518
++ + + + + E K Q + E+ + +++ L +R +
Sbjct: 1243 LILQASLKGELEASQQQVEVYKIQ------LAEITSEK-HKIHEHLKTSAEQHQRTLSAY 1295
Query: 519 SHDVKVLTSKTSAVEMTQAVLNTQLSS-----ENVTKVEQN-SPAVCETISVPK-----S 567
V L + A + QA + ++ S NV K ++N S + ET +
Sbjct: 1296 QQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLE 1355
Query: 568 MSTEEYKSKIQNENMLLLALLSQARKTQK---TVLKDANQTIQDSKPDSCEMNP---NTQ 621
M ++ K K+Q+ L +S+ + Q T+L+ N+ +Q++ E+ + Q
Sbjct: 1356 MLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQ 1415
Query: 622 MTGNQLNLKNMETPSTSNVSGRVLDNSF 649
+ ++ +T S VL NSF
Sbjct: 1416 SENMMMKSEHTQTVSQLTSQNEVLRNSF 1443
>gi|239753231 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 948
Score = 41.2 bits (95), Expect = 0.009
Identities = 150/765 (19%), Positives = 268/765 (35%), Gaps = 142/765 (18%)
Query: 959 PVQCTDVSHKICDQSKSEPPLESSFNNLETNRVILEKSSLEHATEKSTANDTCSSAAIQE 1018
P Q +H + D+ ++L ++ E+ L T K D S AA++
Sbjct: 198 PEQPPLFTHTVKDRDHISTRFLGGMDSLTSSEESSERPPLSTLTLKEA--DPSSKAAMRR 255
Query: 1019 DIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSELLKEFPYGIEAVNTREGSVGQ 1078
P SS P + A ++ DK D +S + E +EG +
Sbjct: 256 KDSPPPGKVSSQKQPAEKATSD---DK-------DSVSNIATEI---------KEGPISG 296
Query: 1079 QTTYQTSEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEE 1138
+ S+ Q A+K +SD KD I I +Q + P++ V+ K
Sbjct: 297 TVS---SQKQPAEKATSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFK-------- 345
Query: 1139 PITEVVSQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSS- 1197
+ VS ++ G + + ++ P + S K S
Sbjct: 346 ---KKVSLLNIATRIMGGGKSGTVSSQKQ------------------PASKATSDKTDSA 384
Query: 1198 ---SEEEKQKEQCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDD 1254
+ E K QC + + + T+D + +V + + + + KS Q
Sbjct: 385 LNIATEIKDGLQCGTVSSQKQPALKATTDEEDSVSNIATEIKDGE-----KSGTVSSQKQ 439
Query: 1255 SRKDTPKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASY 1314
+ S+ E+ G+ S P +S++ +
Sbjct: 440 PALKATTDEKDSVSNIATEIKDGEKSGTVSSQKP------------PALTATSDEEGSVL 487
Query: 1315 EQASQETRQKKHVTQNSRPLKTKTAFLPNKDVY------KKHSSLGQSLSPEKIKLKLKS 1368
A + +K T +SR A KD + KK + + +S +K LK
Sbjct: 488 SIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKKDGEISRKVSSQK-PPTLKG 546
Query: 1369 VSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSVGATFKLGDSLSN--PNERAIVKEKMVS 1426
S ++ L + + +K + E+ + A+ DS+ N ++ K K VS
Sbjct: 547 TSDEEDSVLGIARE-NKDGEKSRTVSSEKPPGLKASSDEKDSVLNIARGKKYGEKTKRVS 605
Query: 1427 NTKSVDTKASSSK---FSRILTPKEYLQRQKHKEALSNKAS--KKICVKNVPCDSEHMRP 1481
+ K +A+S + FS I R+K +S K S K +K + +
Sbjct: 606 SRKKPSLEATSDEKDSFSNI-------TREKKDGEISRKVSSQKPPALKGTSDEED---- 654
Query: 1482 SKLAVQVESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKE--- 1538
S L + E+ K EK S V + K LK ++ NI R K+
Sbjct: 655 SVLGIAREN--KDGEK-SRTVSSEKP---------PGLKATSDEKDSVLNIARGKKDGEK 702
Query: 1539 --KVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLNRVGFKCTERESIS 1596
V ++P + + D + +I+ E + + V +K G K T E S
Sbjct: 703 TRTVSSQKPPTLKATSDEEDSVLSIARENKDGEKSRTVSSEKP-----SGLKATSAEKDS 757
Query: 1597 LTKLESSPRKLHKDKRQENKHKTFLPV--------------KGNTEKSNMLEFKLCPDIL 1642
+ + + K KR ++ K L K + EKS + + P +
Sbjct: 758 VLNIARGKKYGEKTKRVSSRKKPALKATSDEKDSVLYIAREKKDGEKSRTVSSQKQPAL- 816
Query: 1643 LKNTNSVEERKDVKPHPRKEQAPLQVSG-IKSTKEDWLKFVATKK 1686
++ +++D P+ E+ Q+SG + S K+ LK + KK
Sbjct: 817 ----KAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKK 857
Score = 38.9 bits (89), Expect = 0.044
Identities = 139/682 (20%), Positives = 253/682 (37%), Gaps = 101/682 (14%)
Query: 501 DSVLPNPVYSEKRPMPDPSHDVKVLTSKTSAVEMTQAVLNTQLSSENVTKVEQNSPAVCE 560
DS P V S+K+P + D K S A E+ + ++ +SS Q PA
Sbjct: 257 DSPPPGKVSSQKQPAEKATSDDKDSVSNI-ATEIKEGPISGTVSS-------QKQPAEKA 308
Query: 561 TISVPKSMSTEEYKSKIQNENMLLLALLSQARKT----QKTVLKDANQTIQDSKPD--SC 614
T S+S + K ++ + ARK + ++L A + + K S
Sbjct: 309 TSDEKDSVSNIATEIKKGQQSGTVSPQKQSARKVIFKKKVSLLNIATRIMGGGKSGTVSS 368
Query: 615 EMNPNTQMTGNQLNLKNMETPSTSNVSGRVLDNSFCSGQESSTK--GMPAKSDSSCSMEV 672
+ P ++ T ++ T S N++ + D C G SS K + A +D S+
Sbjct: 369 QKQPASKATSDK-------TDSALNIATEIKDGLQC-GTVSSQKQPALKATTDEEDSVSN 420
Query: 673 LATCLS--------LWKKQPSDTAKEKECDKLRTNTTAVGIS-KPANIHVKSPCSVVGNS 723
+AT + +KQP+ A E D + T + K + + P ++ S
Sbjct: 421 IATEIKDGEKSGTVSSQKQPALKATTDEKDSVSNIATEIKDGEKSGTVSSQKPPALTATS 480
Query: 724 NSQNKISN--------------PSQQTALSMVMHNYESSGINITKGTELQIAVVSPLVLS 769
+ + + + S++ S + + S NIT+G + +S V S
Sbjct: 481 DEEGSVLSIARENKDGEKSRTVSSRKKPASKATSDEKDSFSNITRGKK--DGEISRKVSS 538
Query: 770 EVKTLSVKGITPAVLPETVYPVIKEGSVCSLQNQLAENAKATAALKVDVSGPVASTATST 829
+ K ++KG + +E SV + + + K+ G AS+
Sbjct: 539 Q-KPPTLKGTSD-----------EEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDEKD 586
Query: 830 KIFPLTQKEKQNESTNG-NSEVTPNVNQGKHNKLE-SAIHSPMNDQQISQE--SRNSTVV 885
+ + + +K E T +S P++ K S I D +IS++ S+ +
Sbjct: 587 SVLNIARGKKYGEKTKRVSSRKKPSLEATSDEKDSFSNITREKKDGEISRKVSSQKPPAL 646
Query: 886 SSDTLQIDNICSLV-EGDTSYNSQIAKIFSSLPLKMVEPQKPSLPNQQGIGSREPEKQLD 944
+ + D++ + E S+ LK +K S+ N G ++ EK
Sbjct: 647 KGTSDEEDSVLGIARENKDGEKSRTVSSEKPPGLKATSDEKDSVLNIAR-GKKDGEK--- 702
Query: 945 NTTENKDFGFQKDKPVQCTDVSHKICDQSKSEPPLESSFNNLETNRVIL-EKSSLEHATE 1003
+ QK ++ T D+ S + + E +R + EK S AT
Sbjct: 703 ----TRTVSSQKPPTLKATS------DEEDSVLSIARENKDGEKSRTVSSEKPSGLKAT- 751
Query: 1004 KSTANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNEIHSDKAPVLYLHDQLSE------ 1057
S D+ + A + + SS + PA +K VLY+ + +
Sbjct: 752 -SAEKDSVLNIARGKKYGEKTKRVSSR---KKPALKATSDEKDSVLYIAREKKDGEKSRT 807
Query: 1058 LLKEFPYGIEAVNTREGSVGQQTTYQ---------TSEDQTADKTSSDSKDPADQIQITI 1108
+ + ++A+ +E SV T + +S+ Q A K +SD KD I I
Sbjct: 808 VSSQKQPALKAICDKEDSVPNMATEKKDEQISGTVSSQKQPALKATSDKKDSVSNIPTEI 867
Query: 1109 LSSEQMKEIFPEQDDQPYVVDK 1130
+Q + P++ V+ K
Sbjct: 868 KDGQQSGTVSPQKQSAQKVIFK 889
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 40.8 bits (94), Expect = 0.012
Identities = 106/527 (20%), Positives = 210/527 (39%), Gaps = 96/527 (18%)
Query: 1252 QDDSRKDT---PKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKL-----RFHEVT 1303
+D SR +T P KH E+E++A S +L + +KK + H +T
Sbjct: 781 KDVSRLETVFVPPEKH------EKEIIA--LKSNIVELKKQLSELKKKCGEDQEKIHALT 832
Query: 1304 FHSSN-KMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKI 1362
++N K S + +T ++ +T N KT L DV KK + Q E +
Sbjct: 833 SENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELL---DVKKKFEDINQ----EFV 885
Query: 1363 KLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDK------------QEQKGSVGATFKLGDS 1410
K+K K+ K+ + Q + + +H+ Q+ + A ++ G
Sbjct: 886 KIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQE 945
Query: 1411 LSNPNERAIVKEKMVSNTKSVDT--KASSSKFSRILTPKEYLQRQKH-----KEALSNKA 1463
E + ++ + K +DT + K++ I++ +E ++ K K+ LS +
Sbjct: 946 -----EIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQ- 999
Query: 1464 SKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHH 1523
++K V KL ++ + K + ++ S E L+ L
Sbjct: 1000 TQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQL 1059
Query: 1524 SQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLN 1583
S+ Y ++NVKEK+ + + + ++ + N Q +P + + K LN
Sbjct: 1060 KDLSQKYTEVKNVKEKL-------VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLN 1112
Query: 1584 ----------RVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNML 1633
+ +C E+E ++TKL + EN+ + +P+ + +
Sbjct: 1113 GTIENLKEELKSMQRCYEKEQQTVTKLH---------QLLENQKNSSVPLAEHLQIKEAF 1163
Query: 1634 EFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKE-----------DWLKFV 1682
E ++ ++K S+ E+++ + +E + LQ S +++TK+ D K+
Sbjct: 1164 EKEVG---IIK--ASLREKEEESQNKMEEVSKLQ-SEVQNTKQALKKLETREVVDLSKYK 1217
Query: 1683 ATKK--RTQKDS--QERDNVNSRLSKRSFSADGFEMLQNPVKDSKEM 1725
ATK TQ S ++ N+N + + + + KD KE+
Sbjct: 1218 ATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKEL 1264
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 40.8 bits (94), Expect = 0.012
Identities = 106/527 (20%), Positives = 210/527 (39%), Gaps = 96/527 (18%)
Query: 1252 QDDSRKDT---PKTKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKL-----RFHEVT 1303
+D SR +T P KH E+E++A S +L + +KK + H +T
Sbjct: 794 KDVSRLETVFVPPEKH------EKEIIA--LKSNIVELKKQLSELKKKCGEDQEKIHALT 845
Query: 1304 FHSSN-KMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKI 1362
++N K S + +T ++ +T N KT L DV KK + Q E +
Sbjct: 846 SENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELL---DVKKKFEDINQ----EFV 898
Query: 1363 KLKLKSVSFKQKRKLDQGNVLDMEVKKKKHDK------------QEQKGSVGATFKLGDS 1410
K+K K+ K+ + Q + + +H+ Q+ + A ++ G
Sbjct: 899 KIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQE 958
Query: 1411 LSNPNERAIVKEKMVSNTKSVDT--KASSSKFSRILTPKEYLQRQKH-----KEALSNKA 1463
E + ++ + K +DT + K++ I++ +E ++ K K+ LS +
Sbjct: 959 -----EIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQ- 1012
Query: 1464 SKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSSGVQTSKESLNGLTSHGKNLKIHH 1523
++K V KL ++ + K + ++ S E L+ L
Sbjct: 1013 TQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQL 1072
Query: 1524 SQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVKDQKKLYLN 1583
S+ Y ++NVKEK+ + + + ++ + N Q +P + + K LN
Sbjct: 1073 KDLSQKYTEVKNVKEKL-------VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLN 1125
Query: 1584 ----------RVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNML 1633
+ +C E+E ++TKL + EN+ + +P+ + +
Sbjct: 1126 GTIENLKEELKSMQRCYEKEQQTVTKLH---------QLLENQKNSSVPLAEHLQIKEAF 1176
Query: 1634 EFKLCPDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKE-----------DWLKFV 1682
E ++ ++K S+ E+++ + +E + LQ S +++TK+ D K+
Sbjct: 1177 EKEVG---IIK--ASLREKEEESQNKMEEVSKLQ-SEVQNTKQALKKLETREVVDLSKYK 1230
Query: 1683 ATKK--RTQKDS--QERDNVNSRLSKRSFSADGFEMLQNPVKDSKEM 1725
ATK TQ S ++ N+N + + + + KD KE+
Sbjct: 1231 ATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKEL 1277
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 40.4 bits (93), Expect = 0.015
Identities = 47/241 (19%), Positives = 103/241 (42%), Gaps = 21/241 (8%)
Query: 936 SREPEKQLDNTTENKDFGFQKDKPVQCT-----DVSHKICDQSKSEPPLESSFNNLETNR 990
++E E+++ T E+++ +K+ C+ D S + +++ E L+ + E +
Sbjct: 526 NKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHE 585
Query: 991 VILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNE-IHSDKAPVL 1049
+L+K E+ +E S D S + E+ +E D S+ ++ E + D++
Sbjct: 586 NVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDES--- 642
Query: 1050 YLHDQLSELLKEFPYGIEAVNTR-EGSVGQQTTYQTSEDQTADKTSSDSKDPADQIQITI 1108
D+ + G+EA + + E + ++ S+D+ + +D K+ D +
Sbjct: 643 ---DEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDK--EDEDADGKEVEDADEKLF 697
Query: 1109 LSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKD 1168
+ +++F E++D +KL + E + + G S IL S+ D
Sbjct: 698 EDDDSNEKLFDEEEDSS---EKLFDDSDERGTLGGFGSVEEGPLSTG---SSFILSSDDD 751
Query: 1169 D 1169
D
Sbjct: 752 D 752
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 40.4 bits (93), Expect = 0.015
Identities = 47/241 (19%), Positives = 103/241 (42%), Gaps = 21/241 (8%)
Query: 936 SREPEKQLDNTTENKDFGFQKDKPVQCT-----DVSHKICDQSKSEPPLESSFNNLETNR 990
++E E+++ T E+++ +K+ C+ D S + +++ E L+ + E +
Sbjct: 526 NKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHE 585
Query: 991 VILEKSSLEHATEKSTANDTCSSAAIQEDIYPQEIDASSNYTPQDPARNE-IHSDKAPVL 1049
+L+K E+ +E S D S + E+ +E D S+ ++ E + D++
Sbjct: 586 NVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDES--- 642
Query: 1050 YLHDQLSELLKEFPYGIEAVNTR-EGSVGQQTTYQTSEDQTADKTSSDSKDPADQIQITI 1108
D+ + G+EA + + E + ++ S+D+ + +D K+ D +
Sbjct: 643 ---DEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDK--EDEDADGKEVEDADEKLF 697
Query: 1109 LSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVVSQCDLQAPAAGQSRDSVILDSEKD 1168
+ +++F E++D +KL + E + + G S IL S+ D
Sbjct: 698 EDDDSNEKLFDEEEDSS---EKLFDDSDERGTLGGFGSVEEGPLSTG---SSFILSSDDD 751
Query: 1169 D 1169
D
Sbjct: 752 D 752
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 40.4 bits (93), Expect = 0.015
Identities = 98/467 (20%), Positives = 184/467 (39%), Gaps = 75/467 (16%)
Query: 1307 SNKMTASYEQASQETRQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKL 1366
S + T YE +ETRQ ++ N+ K TAF + + E +L++
Sbjct: 193 SAEKTKKYEYEREETRQV-YMDLNNNIEKMITAFEELR------------VQAENSRLEM 239
Query: 1367 KSVSFKQKRKLDQGNVLDMEVKKKKHDKQEQKGSV------------GATFKLGDSLSNP 1414
FK K ++ L+ E KK+ +DK++Q + TF L +S
Sbjct: 240 H---FKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV 296
Query: 1415 NERAIVKEKMVSNTKSVDTKASSSKFSRILTPKEYLQRQKHKEALSNKASK---KICVKN 1471
N+ ++EK + +S + K S K + E ++ + + KA + +I K
Sbjct: 297 NQ---LEEK--TKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKT 351
Query: 1472 VPCDSEHMRPSKLAVQVESCGKSNEKHSSGV---QTSKESL--------NGLTSHGKNLK 1520
+ +E Q+E K+ HS V +T+ SL L + LK
Sbjct: 352 ICQLTEEKE-----TQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLK 406
Query: 1521 IHHSQESKTYNILRNVKEKVGGKQPDKIWIDKTKLDKLTNISNEAQFSQMPPQVK--DQK 1578
I + K + L + + K+ + + K +K T + QF ++ ++K +Q+
Sbjct: 407 ILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEELKGTEQE 466
Query: 1579 KLYLNRVGFKCTERESISLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNMLEFKLC 1638
+ L + K I LT + +S + K+ + +K NTE ++ C
Sbjct: 467 LIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELENEKLK-NTELTSH-----C 520
Query: 1639 PDILLKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKD------- 1691
+ L+N +E D+ + +Q ++ K +E LK + + T+
Sbjct: 521 NKLSLENKELTQETSDMTLELKNQQE--DINNNKKQEERMLKQIENLQETETQLRNELEY 578
Query: 1692 -----SQERDNVNSRLSKRSFSADGF-EMLQNPVKDSKEMFQTYKQM 1732
Q+RD V +L K + + + ++N K +E+ Q K +
Sbjct: 579 VREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKAL 625
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 40.4 bits (93), Expect = 0.015
Identities = 85/450 (18%), Positives = 175/450 (38%), Gaps = 46/450 (10%)
Query: 1085 SEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVV 1144
SED+ +D+ S S ++++ I ++ + + ++ +Q + DK E +K++ TE V
Sbjct: 396 SEDERSDRGSESSDTDDEELRHRI--RQKQEAFWRKEKEQQLLHDKQMEEEKQQ--TERV 451
Query: 1145 SQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQK 1204
++ ++ + +L++ + D G + + P + ++ +EK+K
Sbjct: 452 TK-EMNEFIHKEQNSLSLLEAREAD------GDVVNEKKRTPNETTSVLEPKKEHKEKEK 504
Query: 1205 E---QCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPK 1261
+ + + S RTS TV ++ + G S + SR +PK
Sbjct: 505 QGRSRSGSSSSGSSSSNSRTSSTSSTVS------SSSYSSSSGSS-----RTSSRSSSPK 553
Query: 1262 TKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQET 1321
K + + A + S+ R +++ + + N + + +
Sbjct: 554 RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS 613
Query: 1322 RQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGN 1381
R+++ SR +T A +K +LS K K ++ +Q+RK ++
Sbjct: 614 RERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAK--EQERKKERSR 671
Query: 1382 VLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSK-F 1440
+D + KKK +++ ++ D +R K S + K S + F
Sbjct: 672 SIDKDRKKKDKEREREQ----------DKRKEKQKREEKDFKFSSQDDRLKRKRESERTF 721
Query: 1441 SRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSS 1500
SR + + R ++ S K++ K K+ DS S ES G S EK +
Sbjct: 722 SRSGSISVKIIRHDSRQD-SKKSTTKDSKKHSGSDSSGRSSS------ESPGSSKEKKAK 774
Query: 1501 GVQTSK-ESLNGLTSHGKNLKIHHSQESKT 1529
+ S+ S+ GK H +S++
Sbjct: 775 KPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
>gi|156415994 UTP11-like, U3 small nucleolar ribonucleoprotein [Homo
sapiens]
Length = 253
Score = 40.4 bits (93), Expect = 0.015
Identities = 49/234 (20%), Positives = 90/234 (38%), Gaps = 28/234 (11%)
Query: 1484 LAVQVESCGKSNEK-HSSGVQTSKESLNGLTSHGKNLKIHHSQESKTYNILRNVKEKVGG 1542
+A KS ++ H Q GL K+ K+ K L+ +++K
Sbjct: 1 MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALE 60
Query: 1543 KQPDKIWIDKT--KLDKLTNISNEAQFSQMPPQVK-----DQKKLYLNRVGFKCTERESI 1595
K PD+ + T KL +I E + P Q+K D K + + RV E+
Sbjct: 61 KNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVA------EAK 114
Query: 1596 SLTKLESSPRKLHKDKRQENKHKTFLPVKGNTEKSNM-LEFKLCPDIL------------ 1642
+ +L+S L +Q+NKH F K E+ ++ + P+++
Sbjct: 115 KIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETL 174
Query: 1643 -LKNTNSVEERKDVKPHPRKEQAPLQVSGIKSTKEDWLKFVATKKRTQKDSQER 1695
+ V + +K ++ Q + +E L +A K +T+KD ++
Sbjct: 175 QKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDK 228
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 40.4 bits (93), Expect = 0.015
Identities = 85/450 (18%), Positives = 175/450 (38%), Gaps = 46/450 (10%)
Query: 1085 SEDQTADKTSSDSKDPADQIQITILSSEQMKEIFPEQDDQPYVVDKLAEPQKEEPITEVV 1144
SED+ +D+ S S ++++ I ++ + + ++ +Q + DK E +K++ TE V
Sbjct: 396 SEDERSDRGSESSDTDDEELRHRI--RQKQEAFWRKEKEQQLLHDKQMEEEKQQ--TERV 451
Query: 1145 SQCDLQAPAAGQSRDSVILDSEKDDIHCCALGWLSMVYEGVPQCQCNSIKNSSSEEEKQK 1204
++ ++ + +L++ + D G + + P + ++ +EK+K
Sbjct: 452 TK-EMNEFIHKEQNSLSLLEAREAD------GDVVNEKKRTPNETTSVLEPKKEHKEKEK 504
Query: 1205 E---QCSPLDTNSCKQGERTSDRDVTVVQFKSLVNNPKTPPDGKSHFPELQDDSRKDTPK 1261
+ + + S RTS TV ++ + G S + SR +PK
Sbjct: 505 QGRSRSGSSSSGSSSSNSRTSSTSSTVS------SSSYSSSSGSS-----RTSSRSSSPK 553
Query: 1262 TKHKSLPRTEQELVAGQFSSKCDKLNPLQNHKRKKLRFHEVTFHSSNKMTASYEQASQET 1321
K + + A + S+ R +++ + + N + + +
Sbjct: 554 RKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPS 613
Query: 1322 RQKKHVTQNSRPLKTKTAFLPNKDVYKKHSSLGQSLSPEKIKLKLKSVSFKQKRKLDQGN 1381
R+++ SR +T A +K +LS K K ++ +Q+RK ++
Sbjct: 614 RERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAK--EQERKKERSR 671
Query: 1382 VLDMEVKKKKHDKQEQKGSVGATFKLGDSLSNPNERAIVKEKMVSNTKSVDTKASSSK-F 1440
+D + KKK +++ ++ D +R K S + K S + F
Sbjct: 672 SIDKDRKKKDKEREREQ----------DKRKEKQKREEKDFKFSSQDDRLKRKRESERTF 721
Query: 1441 SRILTPKEYLQRQKHKEALSNKASKKICVKNVPCDSEHMRPSKLAVQVESCGKSNEKHSS 1500
SR + + R ++ S K++ K K+ DS S ES G S EK +
Sbjct: 722 SRSGSISVKIIRHDSRQD-SKKSTTKDSKKHSGSDSSGRSSS------ESPGSSKEKKAK 774
Query: 1501 GVQTSK-ESLNGLTSHGKNLKIHHSQESKT 1529
+ S+ S+ GK H +S++
Sbjct: 775 KPKHSRSRSVEKSQRSGKKASRKHKSKSRS 804
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.123 0.341
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,151,342
Number of Sequences: 37866
Number of extensions: 3113581
Number of successful extensions: 10892
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 271
Number of HSP's that attempted gapping in prelim test: 10324
Number of HSP's gapped (non-prelim): 873
length of query: 1747
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1631
effective length of database: 13,855,062
effective search space: 22597606122
effective search space used: 22597606122
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.