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Search of human proteins with 63162572
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|63162572 chaperonin containing TCP1, subunit 3 isoform a
[Homo sapiens]
(545 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 1066 0.0
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 1060 0.0
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 972 0.0
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 306 3e-83
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 300 2e-81
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 290 2e-78
gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 286 3e-77
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 265 6e-71
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 259 4e-69
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 227 2e-59
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 218 9e-57
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho... 204 2e-52
gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 167 2e-41
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom... 163 3e-40
gi|7657253 T-complex protein 1 [Homo sapiens] 157 3e-38
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 99 1e-20
gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens] 76 7e-14
gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens] 76 7e-14
gi|41399285 chaperonin [Homo sapiens] 59 9e-09
gi|31542947 chaperonin [Homo sapiens] 59 9e-09
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] 50 7e-06
gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens] 35 0.23
gi|14251207 MOV10-like 1 [Homo sapiens] 32 1.9
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 32 1.9
gi|10190716 spindle pole body component 25 [Homo sapiens] 32 1.9
gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens] 31 2.5
gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens] 31 2.5
gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens] 31 2.5
gi|11968182 ribosomal protein S18 [Homo sapiens] 31 2.5
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 30 4.3
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 1066 bits (2757), Expect = 0.0
Identities = 545/545 (100%), Positives = 545/545 (100%)
Query: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT
Sbjct: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
Query: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 120
NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT
Sbjct: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 120
Query: 121 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 180
VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
Sbjct: 121 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 180
Query: 181 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240
KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
Sbjct: 181 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240
Query: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300
LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
Sbjct: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300
Query: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360
QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
Sbjct: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360
Query: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420
TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
Sbjct: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420
Query: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 480
ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
Sbjct: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 480
Query: 481 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 540
NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
Sbjct: 481 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 540
Query: 541 DAGQE 545
DAGQE
Sbjct: 541 DAGQE 545
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 1060 bits (2741), Expect = 0.0
Identities = 544/545 (99%), Positives = 544/545 (99%), Gaps = 1/545 (0%)
Query: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT
Sbjct: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
Query: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 120
NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL GEMLSVAEHFLEQQMHPT
Sbjct: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPT 119
Query: 121 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 180
VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
Sbjct: 120 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 179
Query: 181 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240
KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
Sbjct: 180 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 239
Query: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300
LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
Sbjct: 240 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 299
Query: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360
QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
Sbjct: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 359
Query: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420
TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
Sbjct: 360 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 419
Query: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 480
ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
Sbjct: 420 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 479
Query: 481 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 540
NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
Sbjct: 480 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 539
Query: 541 DAGQE 545
DAGQE
Sbjct: 540 DAGQE 544
>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
sapiens]
Length = 507
Score = 973 bits (2514), Expect = 0.0
Identities = 507/545 (93%), Positives = 507/545 (93%), Gaps = 38/545 (6%)
Query: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
MMGHRPVLVLSQNTKRESGRKVQSGNINAAK
Sbjct: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAK----------------------------- 31
Query: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 120
IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT
Sbjct: 32 ---------IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 82
Query: 121 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 180
VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
Sbjct: 83 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 142
Query: 181 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240
KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
Sbjct: 143 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 202
Query: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300
LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
Sbjct: 203 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 262
Query: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360
QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
Sbjct: 263 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 322
Query: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420
TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
Sbjct: 323 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 382
Query: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 480
ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
Sbjct: 383 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 442
Query: 481 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 540
NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
Sbjct: 443 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 502
Query: 541 DAGQE 545
DAGQE
Sbjct: 503 DAGQE 507
>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
sapiens]
Length = 539
Score = 306 bits (784), Expect = 3e-83
Identities = 178/515 (34%), Positives = 302/515 (58%), Gaps = 10/515 (1%)
Query: 16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75
R+ +++ NI+AAK +AD IRT LGPK M KM+ D G + +TNDG IL+++QV HP
Sbjct: 27 RDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHP 86
Query: 76 AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 135
AA+ ++E+S+ QD E GDGTTSV+I+AG +L L++ +HPT++ +++KAL+ I
Sbjct: 87 AARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIE 146
Query: 136 TLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDI 195
L +S PV++SD + +LN +S+ +K +S++SSL ++++AV V + +D+
Sbjct: 147 ILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKV-IDPATATSVDL 205
Query: 196 KKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTD 255
+ V+K+ GG I+D ++ G+++ + V++ + R ++ +I L+ L K +
Sbjct: 206 RDIKIVKKL-GGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAPKTDMDNQ 263
Query: 256 IEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGI-----SDLAQHYLMRANIT 310
I ++ R+L+ E YI L + I + +V++ +K I SDLA H+L + I
Sbjct: 264 IVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIM 323
Query: 311 AIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDP- 369
I+ + + D I + G + V+ ++ D +G+ E+ G IT C P
Sbjct: 324 VIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPG 383
Query: 370 KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAM 429
K TI++RG++K ++ E ER++ DA+ V R ++ L+ GGGA E+ +A LTE S+ +
Sbjct: 384 KTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTL 443
Query: 430 TGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVD 489
+G+E + RA A A+EVIP TL +N G + I +T LR +H Q +T G+N G + +
Sbjct: 444 SGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE-KTAGINVRKGGISN 502
Query: 490 MKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 524
+ E + +PL V + A ET +L+IDD+V+
Sbjct: 503 ILEELVVQPLLVSVSALTLATETVRSILKIDDVVN 537
>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
sapiens]
Length = 541
Score = 300 bits (769), Expect = 2e-81
Identities = 179/535 (33%), Positives = 310/535 (57%), Gaps = 14/535 (2%)
Query: 5 RPVLVLSQNTKRES--GRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTND 62
RP L++ ++ G + +I AAK +A+ +RT LGP + KM++D G + +TND
Sbjct: 14 RPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTND 73
Query: 63 GNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVV 122
G IL + V H AK M+E+S++QD+E+GDGTT V++LAG +L AE L++ +HP +
Sbjct: 74 GATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRI 133
Query: 123 ISAYRKALDDMISTLKKI--SIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 180
Y +A I L KI S+ VDI D++ ++ +++ +K ++ IA++AV
Sbjct: 134 ADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAV 193
Query: 181 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240
V E R+++D + +VE GG +ED+ +++GV+++KD +HP+M + +++ +I +
Sbjct: 194 LTVADME--RRDVDF-ELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAI 250
Query: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300
L E K +++ +++T ED+ + + E+E +++ + I + ++ I + G D A
Sbjct: 251 LTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEA 310
Query: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIG--DE 358
H L++ N+ A+R V + IA A G RIV R EL + +G AGL++ G +
Sbjct: 311 NHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGF-AGLVQEISFGTTKD 369
Query: 359 YFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAV 418
I CK+ +A TI +RG +K I+ E +R+L DA+ V RN++ D ++V GGGA+E++
Sbjct: 370 KMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISC 429
Query: 419 AHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETW 478
A A+++++ +EQ+ RA A ALEVIP L +N G + I+ +T +RA+ +E
Sbjct: 430 ALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPAL 489
Query: 479 GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQ 533
G++ DMK+ + E L K Q A + ++L+IDDI +K G+ +
Sbjct: 490 GIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI----RKPGESE 540
>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
sapiens]
Length = 543
Score = 290 bits (743), Expect = 2e-78
Identities = 173/547 (31%), Positives = 287/547 (52%), Gaps = 18/547 (3%)
Query: 6 PVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNA 65
PV++L + T G NI+A + IA+ +RT LGP+ M K+++D G ++NDG
Sbjct: 5 PVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGAT 64
Query: 66 ILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISA 125
IL+ + V HPAAK++++I+++QD EVGDGTTSV +LA E L + ++E+ +HP ++I A
Sbjct: 65 ILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRA 124
Query: 126 YRKALDDMISTLKKISIPVDISDSDMMLNIIN----SSITTKAISRWSSLACNIALDAVK 181
+R A ++ +K+I++ V +D ++ +++++K IS+ + + +DAV
Sbjct: 125 FRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVM 184
Query: 182 MVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIK---NPRI 238
M+ ++ K ++K+ GG +EDS ++ GV K ++ K NP+I
Sbjct: 185 MLD-------DLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKI 237
Query: 239 VLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISD 298
LL+ LE K + +I + ED+ I+ E + E I VV+++ I D
Sbjct: 238 ALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGD 297
Query: 299 LAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDE 358
+A Y ++ RV + D R ACG I + L D +G + E +IG E
Sbjct: 298 VATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGR-CQVFEETQIGGE 356
Query: 359 YFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAV 418
+ F T C K CT +LRG +++ + E ER+L DA+ + R + + +V GGGA EM +
Sbjct: 357 RYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMEL 416
Query: 419 AHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETW 478
+ L + S+ + G +Q A A+ALE+IPR L N G +L LRA+H Q TW
Sbjct: 417 SKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGG--TW 474
Query: 479 -GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQG 537
GV+ + D E +WEP V++ A E A L++ +D+ + + D + G
Sbjct: 475 YGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAG 534
Query: 538 GAPDAGQ 544
G+
Sbjct: 535 RGRGRGR 541
>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
Length = 556
Score = 286 bits (733), Expect = 3e-77
Identities = 181/541 (33%), Positives = 297/541 (54%), Gaps = 17/541 (3%)
Query: 16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75
R +G ++S N+ AA +IA+I+++ LGP + KML+D +G + +TNDG IL+ ++V+HP
Sbjct: 11 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70
Query: 76 AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 135
AAK + E++ QD+EVGDGTTSV+I+A E+L A+ ++Q++HPT VIS YR A + +
Sbjct: 71 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
Query: 136 TL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEI 193
+ + + + D D ++N +S+++K I N+ +DAV +++ + G+
Sbjct: 131 YINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRY 190
Query: 194 DIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQ 253
+ + K G +S ++ G +N V M + I N +I LD SL+ K +
Sbjct: 191 PVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLG 249
Query: 254 TDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIR 313
+ IT E +I Q E + ++ + I+ +V++T GI D+ Y + A A+R
Sbjct: 250 VQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVR 309
Query: 314 RVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTFITDCKD 368
RV K D RIA+A GA I+S L ++ A L + ++I D+ I + K
Sbjct: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369
Query: 369 PKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKA 428
+ +I+LRGA+ + E+ER+L DA+ V + VL +VPGGGA E A++ L + +
Sbjct: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429
Query: 429 MTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENCETWGVN 481
M EQ A++L VIP TL N + L+ LRA H + +N + G++
Sbjct: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489
Query: 482 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 541
G D K+ G++EP VK+++ K A E A+ +LRIDD++ H + DD + G D
Sbjct: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--KHGSYED 547
Query: 542 A 542
A
Sbjct: 548 A 548
>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
sapiens]
Length = 531
Score = 265 bits (678), Expect = 6e-71
Identities = 148/507 (29%), Positives = 289/507 (57%), Gaps = 16/507 (3%)
Query: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
NI+AA+ + D++RT LGPK MKML+ G I +T DGN +L E+Q+QHP A + +++
Sbjct: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
Query: 86 TQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVD 145
QD+ GDGTTS +++ GE+L A+ ++ + +HP ++ + A + + L+++ + +
Sbjct: 83 AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSRE 142
Query: 146 ISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIP 205
+ D + ++++ +S+ TK + + + +D++ ++ ++ + ID+ + ++
Sbjct: 143 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EPIDL-FMIEIMEMK 197
Query: 206 GGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFT 265
D+ ++RG++++ HP M++ +++ I+ + SLEY+K E + E+
Sbjct: 198 HKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEERE 257
Query: 266 RILQMEEEYIQQLCEDIIQLKPD---------VVITEKGISDLAQHYLMRANITAIRRVR 316
++++ E ++I+ + II+LK VVI +KGI + L + I A+RR +
Sbjct: 258 KLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAK 317
Query: 317 KTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 376
+ + R+ ACG ++ ++L D +G AGL+ +G+E FTFI C +P++ T+L+
Sbjct: 318 RRNMERLTLACGGVALNSFDDLSPDCLG-HAGLVYEYTLGEEKFTFIEKCNNPRSVTLLI 376
Query: 377 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 436
+G +K L++++ ++D ++ +N + D +VPG GA E+A+A AL + ++ G Q
Sbjct: 377 KGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLG 436
Query: 437 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 496
+A A AL +IP+ L QN G L ++A+H+ E+ + GV+ TG + E+G+W
Sbjct: 437 VQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-ESGQLVGVDLNTGEPMVAAEVGVW 495
Query: 497 EPLAVKLQTYKTAVETAVLLLRIDDIV 523
+ VK Q + A +L +D+I+
Sbjct: 496 DNYCVKKQLLHSCTVIATNILLVDEIM 522
>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
Length = 530
Score = 259 bits (662), Expect = 4e-69
Identities = 154/523 (29%), Positives = 289/523 (55%), Gaps = 20/523 (3%)
Query: 13 NTKRE--SGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREI 70
N+K E R + NI AA+ + D++RT LGPK MKML+ G I +T DGN +L E+
Sbjct: 8 NSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEM 67
Query: 71 QVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKAL 130
Q+QHP A + +++ QD+ GDGTTS +++ GE+L A+ ++ + +HP ++ + A
Sbjct: 68 QIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAK 127
Query: 131 DDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGR 190
+ L+++ + ++ ++L++ +S+ TK + + + + +D+V V+ R
Sbjct: 128 IKALEVLEEVKVTKEMK-RKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR-----R 181
Query: 191 KEIDIKKY-ARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKK 249
I + + ++ + D+ +++G++++ HP M++ +++ I++ + SLEY+K
Sbjct: 182 PGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEK 241
Query: 250 GESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPD---------VVITEKGISDLA 300
E + E+ ++++ E ++I+ + II LK VVI +KGI +
Sbjct: 242 TEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFS 301
Query: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360
L + I A+RR ++ + R++ ACG V+ E+L D +G AGL+ +G+E F
Sbjct: 302 LDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLG-HAGLVYEYTLGEEKF 360
Query: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420
TFI +C +P + T+L++G +K L++V+ ++D ++ +N + D +VPG GA E+A+A
Sbjct: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420
Query: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 480
AL ++ G + +A A AL +IP+ L QN G L ++A+H E+ + GV
Sbjct: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHV-ESKQLVGV 479
Query: 481 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 523
+ TG + + G+W+ VK Q + A +L +D+I+
Sbjct: 480 DLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
Length = 535
Score = 227 bits (579), Expect = 2e-59
Identities = 159/532 (29%), Positives = 275/532 (51%), Gaps = 20/532 (3%)
Query: 6 PVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPM--GGIVMTNDG 63
PV + E + + A I D++++ LGPK M K+LL +++TNDG
Sbjct: 8 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG 67
Query: 64 NAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVI 123
IL+ I V +PAAK ++++SR QD+EVGDGTTSV +LA E+L AE + +++HP +I
Sbjct: 68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII 127
Query: 124 SAYRKALDDMISTLKKISIPVDISDSDM-----MLNIINSSITTKAISRWSSLACNIALD 178
+ +R+A L +S VD ++ ++NI +++++K ++ +A++
Sbjct: 128 AGWREATKAAREAL--LSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185
Query: 179 AVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRI 238
AV ++ N IKK GG + DS + G +++K + + +R I+N +I
Sbjct: 186 AVLRLKGSGNLEAIHIIKKL-------GGSLADSYLDEGFLLDKKIGVNQPKR-IENAKI 237
Query: 239 VLLDSSLEYKKGES-QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGIS 297
++ ++ ++ K + + + + I E+E +++ E I++ + I + I
Sbjct: 238 LIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIY 297
Query: 298 DLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD 357
+ + A + AI R+A G I S + +G+ L+E IG+
Sbjct: 298 NYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGS-CKLIEEVMIGE 356
Query: 358 EYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMA 417
+ + +ACTI+LRGA+++IL E ER+L DA+ V + D + V GGG SEM
Sbjct: 357 DKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEML 416
Query: 418 VAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCET 477
+AHA+T+ + G E + A+AL ++P + N G + L+ LRA H++ N T
Sbjct: 417 MAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN-TT 475
Query: 478 WGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKK 529
G++ GT+ DM LGI E VK Q +A E A ++LR+D+I+ +K
Sbjct: 476 AGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK 527
>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
sapiens]
Length = 548
Score = 218 bits (556), Expect = 9e-57
Identities = 162/546 (29%), Positives = 264/546 (48%), Gaps = 32/546 (5%)
Query: 9 VLSQNTKRESG-RKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAIL 67
+L + K SG + NI A K +A RT GP M KM+++ + + +TND IL
Sbjct: 14 MLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATIL 73
Query: 68 REIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYR 127
RE++VQHPAAK ++ S Q++EVGDGT V++ AG +L +AE L + + VI Y
Sbjct: 74 RELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYE 133
Query: 128 KALDDMISTLKKI--SIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQF 185
A L + ++ D D + +++ +SI +K LA IA V + F
Sbjct: 134 IACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSI--F 191
Query: 186 EENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINK----DVTHPRMRRYIKNPRIVLL 241
++G +D RV KI G I S VL G++ K DVT +K+ +I +
Sbjct: 192 PDSGHFNVD---NIRVCKILGSGISSSSVLHGMVFKKETEGDVTS------VKDAKIAVY 242
Query: 242 DSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQ 301
+ E++ + I E+ + EE + + I +VV+T ++D+A
Sbjct: 243 SCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMAL 302
Query: 302 HYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD-EYF 360
HY + NI +R K D R+ + GA + R +++G + + ++GD +
Sbjct: 303 HYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMG-HCDSVYLSEVGDTQVV 361
Query: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420
F + +D TI+LRG++ ++ ++ER + D + + + D +LVPGGGA+E+ +A
Sbjct: 362 VFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAK 421
Query: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCET-WG 479
+T + G+EQ+ + A+A E IPR L +N G +++ L A H + N
Sbjct: 422 QITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLD 481
Query: 480 VNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV-----------SGHKK 528
+ E + DM E GI + K K A AV +LR+D I+ SG K
Sbjct: 482 IEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKD 541
Query: 529 KGDDQS 534
DDQ+
Sbjct: 542 WDDDQN 547
>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
sapiens]
Length = 486
Score = 204 bits (518), Expect = 2e-52
Identities = 132/507 (26%), Positives = 258/507 (50%), Gaps = 61/507 (12%)
Query: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
NI+AA+ + D++RT LGPK MKML+ G I +T DGN +L E+
Sbjct: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMG-------------- 68
Query: 86 TQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVD 145
+HP ++ + A + + L+++ + +
Sbjct: 69 -------------------------------LHPRIITEGFEAAKEKALQFLEEVKVSRE 97
Query: 146 ISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIP 205
+ D + ++++ +S+ TK + + + +D++ ++ ++ + ID+ +E +
Sbjct: 98 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EPIDLFMIEIME-MK 152
Query: 206 GGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFT 265
D+ ++RG++++ HP M++ +++ I+ + SLEY+K E + E+
Sbjct: 153 HKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEERE 212
Query: 266 RILQMEEEYIQQLCEDIIQLKPDV---------VITEKGISDLAQHYLMRANITAIRRVR 316
++++ E ++I+ + II+LK V VI +KGI + L + I A+RR +
Sbjct: 213 KLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAK 272
Query: 317 KTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 376
+ + R+ ACG ++ ++L D +G AGL+ +G+E FTFI C +P++ T+L+
Sbjct: 273 RRNMERLTLACGGVALNSFDDLSPDCLGH-AGLVYEYTLGEEKFTFIEKCNNPRSVTLLI 331
Query: 377 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 436
+G +K L++++ ++D ++ +N + D +VPG GA E+A+A AL + ++ G Q
Sbjct: 332 KGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLG 391
Query: 437 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 496
+A A AL +IP+ L QN G L ++A+H+ E+ + GV+ TG + E+G+W
Sbjct: 392 VQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-ESGQLVGVDLNTGEPMVAAEVGVW 450
Query: 497 EPLAVKLQTYKTAVETAVLLLRIDDIV 523
+ VK Q + A +L +D+I+
Sbjct: 451 DNYCVKKQLLHSCTVIATNILLVDEIM 477
>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
Length = 401
Score = 167 bits (424), Expect = 2e-41
Identities = 121/396 (30%), Positives = 198/396 (50%), Gaps = 16/396 (4%)
Query: 160 ITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEIDIKKYARVEKIPGGIIEDSCVLRGV 218
+++K I N+ +DAV +++ + G+ + + K G +S ++ G
Sbjct: 1 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNS-VNILKAHGRSQMESMLISGY 59
Query: 219 MINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQL 278
+N V M + I N +I LD SL+ K + + IT E +I Q E + ++
Sbjct: 60 ALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKER 119
Query: 279 CEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEEL 338
+ I+ +V++T GI D+ Y + A A+RRV K D RIA+A GA I+S L
Sbjct: 120 IQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANL 179
Query: 339 REDDVGTGAGLLEIK-----KIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQD 393
++ A L + + +I D+ I + K + +I+LRGA+ + E+ER+L D
Sbjct: 180 EGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHD 239
Query: 394 AMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQ 453
A+ V + VL +VPGGGA E A++ L + +M EQ A++L VIP TL
Sbjct: 240 ALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAV 299
Query: 454 NCGASTIRLLTSLRAKHTQ-------ENCETWGVNGETGTLVDMKELGIWEPLAVKLQTY 506
N + L+ LRA H + +N + G++ G D K+ G++EP VK+++
Sbjct: 300 NAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSL 359
Query: 507 KTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPDA 542
K A E A+ +LRIDD++ H + DD + G DA
Sbjct: 360 KFATEAAITILRIDDLIKLHPESKDD--KHGSYEDA 393
>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
sapiens]
Length = 339
Score = 163 bits (413), Expect = 3e-40
Identities = 104/338 (30%), Positives = 162/338 (47%), Gaps = 7/338 (2%)
Query: 211 DSCVLRGVMINKDVTHPRMRRYIK---NPRIVLLDSSLEYKKGESQTDIEITREEDFTRI 267
DS ++ GV K ++ K NP+I LL+ LE K + +I + ED+ I
Sbjct: 3 DSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQAI 62
Query: 268 LQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC 327
+ E + E I VV+++ I D+A Y ++ RV + D R AC
Sbjct: 63 VDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMAC 122
Query: 328 GARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEV 387
G I + L D +G + E +IG E + F T C K CT +LRG +++ + E
Sbjct: 123 GGSIQTSVNALSADVLGR-CQVFEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEET 181
Query: 388 ERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVI 447
ER+L DA+ + R + + +V GGGA EM ++ L + S+ + G +Q A A+ALE+I
Sbjct: 182 ERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEII 241
Query: 448 PRTLIQNCGASTIRLLTSLRAKHTQENCETW-GVNGETGTLVDMKELGIWEPLAVKLQTY 506
PR L N G +L LRA+H Q TW GV+ + D E +WEP V++
Sbjct: 242 PRQLCDNAGFDATNILNKLRARHAQGG--TWYGVDINNEDIADNFEAFVWEPAMVRINAL 299
Query: 507 KTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPDAGQ 544
A E A L++ +D+ + + D + G G+
Sbjct: 300 TAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGR 337
>gi|7657253 T-complex protein 1 [Homo sapiens]
Length = 557
Score = 157 bits (396), Expect = 3e-38
Identities = 127/513 (24%), Positives = 232/513 (45%), Gaps = 34/513 (6%)
Query: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
++ A +T+A +IR C GP K L+ G V T AILR ++++HPAA + E +
Sbjct: 36 SLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLREAGQ 95
Query: 86 TQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPV- 144
TQ E GDGT V++L +L AE L+ + + AY A ++++TL ++I
Sbjct: 96 TQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAIQSL 155
Query: 145 -DISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEK 203
+ D L+ + ++ T + + L + A A+K + + V
Sbjct: 156 GPLEDPSWALHSVMNTHTLSPMDHLTKLVAH-ACWAIKELDGSFKPER-------VGVCA 207
Query: 204 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREED 263
+PGG +EDSC+L G+ I+ + +M + R+ L + ++ D
Sbjct: 208 LPGGTLEDSCLLPGLAISGKLCG-QMATVLSGARVALFACPFGPAHPNAPATARLSSPAD 266
Query: 264 FTRIL----QMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLM-----RANITAIRR 314
+ Q+ E+ + QL I + + ++ LA Y + R+ + I
Sbjct: 267 LAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKYGIVVIQARSWMEIIYL 326
Query: 315 VRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTI 374
D + R + + + + ++G G ++ F +C A T+
Sbjct: 327 SEVLDTPLLPRLLPPQRPGKCQRVYRQELGDGLAVV-----------FEWECTGTPALTV 375
Query: 375 LLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQ 434
+LRGA+ + L E+ + + + DP+L+PG GA+EMA+A L++K + G
Sbjct: 376 VLRGATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSG 435
Query: 435 WPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELG 494
+ A A AL+ +P+TL +N G + ++ + H N GV T ++++ + G
Sbjct: 436 PAFLAFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNL-LMGVG--TEGIINVAQEG 492
Query: 495 IWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHK 527
+W+ L VK Q ++ E + L+ +D+IV K
Sbjct: 493 VWDTLIVKAQGFRAVAEVVLQLVTVDEIVVAKK 525
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 98.6 bits (244), Expect = 1e-20
Identities = 68/232 (29%), Positives = 119/232 (51%), Gaps = 12/232 (5%)
Query: 166 SRWSSLACNIALDAVKMVQFE-ENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDV 224
S W + ++ V+ V+ + +N ++DI+++ ++KIPGG DS V+ G + K++
Sbjct: 631 SSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNI 690
Query: 225 THPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQ 284
H +M IKNP+I+LL S+EY E T+ I+ E E+++ + I+
Sbjct: 691 AHKKMSSCIKNPKILLLKCSIEYLYREE------TKFTCIDPIVLQEREFLKNYVQRIVD 744
Query: 285 LKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC-GARIVSRPEELREDDV 343
++P +V+ EK +S +AQ L+ IT + V+ RI+R G ++S + L + +
Sbjct: 745 VRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHL 804
Query: 344 GT-GAGLLEIKKIGDEY---FTFITDCKDPKACTILLRGASKEILSEVERNL 391
GT ++I ++ +E F C CTI LRG S L+ V+ L
Sbjct: 805 GTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEIL 856
>gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 76.3 bits (186), Expect = 7e-14
Identities = 89/402 (22%), Positives = 165/402 (41%), Gaps = 19/402 (4%)
Query: 36 IIRTCLGPKSMMKMLLDPMGGIVMT-NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDG 94
I+ +C GP +K L + GG V T + +A+L + V HP K + + D
Sbjct: 32 IVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDC 91
Query: 95 TTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKIS----IPVDISDSD 150
IL ++ E+ + PT VI + L IS LK + IPVD S +
Sbjct: 92 GLFTAILCCNLI---ENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQ 148
Query: 151 MMLNIINSSITTKA---ISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGG 207
++L ++ S +T+K ++R + + + ++ EN I + K + + + G
Sbjct: 149 ILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGK-SLIVPLKGQ 207
Query: 208 IIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRI 267
+ DS VL G++I IK + + G++ E T +
Sbjct: 208 RVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYG-- 265
Query: 268 LQMEEEYIQQLCE---DIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIA 324
+ +E + QL +I D+V+ +K I + +L I AI R+ T +
Sbjct: 266 VSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLT 325
Query: 325 RACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEIL 384
+ G + + + + G+ + K +F I + + C++LL +
Sbjct: 326 KMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFHLIPN--EATICSLLLCNRNDTAW 383
Query: 385 SEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKS 426
E++ Q A+ V + L +P + GGG +E +A + K+
Sbjct: 384 DELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKT 425
>gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 76.3 bits (186), Expect = 7e-14
Identities = 89/402 (22%), Positives = 165/402 (41%), Gaps = 19/402 (4%)
Query: 36 IIRTCLGPKSMMKMLLDPMGGIVMT-NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDG 94
I+ +C GP +K L + GG V T + +A+L + V HP K + + D
Sbjct: 32 IVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDC 91
Query: 95 TTSVIILAGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKIS----IPVDISDSD 150
IL ++ E+ + PT VI + L IS LK + IPVD S +
Sbjct: 92 GLFTAILCCNLI---ENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQ 148
Query: 151 MMLNIINSSITTKA---ISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGG 207
++L ++ S +T+K ++R + + + ++ EN I + K + + + G
Sbjct: 149 ILLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGK-SLIVPLKGQ 207
Query: 208 IIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRI 267
+ DS VL G++I IK + + G++ E T +
Sbjct: 208 RVIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYG-- 265
Query: 268 LQMEEEYIQQLCE---DIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIA 324
+ +E + QL +I D+V+ +K I + +L I AI R+ T +
Sbjct: 266 VSLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLT 325
Query: 325 RACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEIL 384
+ G + + + + G+ + K +F I + + C++LL +
Sbjct: 326 KMTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFHLIPN--EATICSLLLCNRNDTAW 383
Query: 385 SEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKS 426
E++ Q A+ V + L +P + GGG +E +A + K+
Sbjct: 384 DELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKT 425
>gi|41399285 chaperonin [Homo sapiens]
Length = 573
Score = 59.3 bits (142), Expect = 9e-09
Identities = 123/575 (21%), Positives = 225/575 (39%), Gaps = 78/575 (13%)
Query: 5 RPVL-VLSQNTKRESGRKVQSGN------INAAKTIADIIRTCLGPKSMMKMLLDPMGGI 57
RPV VL+ + R + V+ G + +AD + +GPK ++ G
Sbjct: 12 RPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSP 71
Query: 58 VMTNDGNAILREIQVQHP----AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFL 113
+T DG + + I ++ AK + +++ +EE GDGTT+ +LA + +
Sbjct: 72 KVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKI 131
Query: 114 EQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLAC 173
+ +P + A+D +I+ LKK S PV + + I+++ K I
Sbjct: 132 SKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG------- 183
Query: 174 NIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYI 233
NI DA+K V GRK + K + IIE RG + + + ++
Sbjct: 184 NIISDAMKKV-----GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCE 238
Query: 234 KNPRIVLLDS-----------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQL 278
VLL +LE + + I + D T +L + +Q +
Sbjct: 239 FQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVV 298
Query: 279 C--------------EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTDN 320
+D+ V E+G++ D+ H L + + + D+
Sbjct: 299 AVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----DD 354
Query: 321 NRIARACG--ARIVSRPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLR 377
+ + G A+I R +E+ E DV T E +K+ +E ++D + +
Sbjct: 355 AMLLKGKGDKAQIEKRIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKVG 407
Query: 378 GASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPY 437
G S ++E + + DA+ R ++ +V GGG + + AL + A ++
Sbjct: 408 GTSDVEVNEKKDRVTDALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIGI 465
Query: 438 RAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWE 497
+ + L++ T+ +N G SL + ++ G + G V+M E GI +
Sbjct: 466 EIIKRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIID 520
Query: 498 PLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDD 532
P V A A LL + +V+ K+ D
Sbjct: 521 PTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKD 555
>gi|31542947 chaperonin [Homo sapiens]
Length = 573
Score = 59.3 bits (142), Expect = 9e-09
Identities = 123/575 (21%), Positives = 225/575 (39%), Gaps = 78/575 (13%)
Query: 5 RPVL-VLSQNTKRESGRKVQSGN------INAAKTIADIIRTCLGPKSMMKMLLDPMGGI 57
RPV VL+ + R + V+ G + +AD + +GPK ++ G
Sbjct: 12 RPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSP 71
Query: 58 VMTNDGNAILREIQVQHP----AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFL 113
+T DG + + I ++ AK + +++ +EE GDGTT+ +LA + +
Sbjct: 72 KVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKI 131
Query: 114 EQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLAC 173
+ +P + A+D +I+ LKK S PV + + I+++ K I
Sbjct: 132 SKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG------- 183
Query: 174 NIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYI 233
NI DA+K V GRK + K + IIE RG + + + ++
Sbjct: 184 NIISDAMKKV-----GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCE 238
Query: 234 KNPRIVLLDS-----------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQL 278
VLL +LE + + I + D T +L + +Q +
Sbjct: 239 FQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVV 298
Query: 279 C--------------EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTDN 320
+D+ V E+G++ D+ H L + + + D+
Sbjct: 299 AVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----DD 354
Query: 321 NRIARACG--ARIVSRPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLR 377
+ + G A+I R +E+ E DV T E +K+ +E ++D + +
Sbjct: 355 AMLLKGKGDKAQIEKRIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKVG 407
Query: 378 GASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPY 437
G S ++E + + DA+ R ++ +V GGG + + AL + A ++
Sbjct: 408 GTSDVEVNEKKDRVTDALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIGI 465
Query: 438 RAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWE 497
+ + L++ T+ +N G SL + ++ G + G V+M E GI +
Sbjct: 466 EIIKRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIID 520
Query: 498 PLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDD 532
P V A A LL + +V+ K+ D
Sbjct: 521 PTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKD 555
>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
Length = 723
Score = 49.7 bits (117), Expect = 7e-06
Identities = 21/100 (21%), Positives = 52/100 (52%), Gaps = 4/100 (4%)
Query: 24 SGNINAAKTIADIIRT----CLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKS 79
+G++ AA +A+++ C+GP+ + P G ++++ +G +L + ++HP A+
Sbjct: 8 AGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARM 67
Query: 80 MIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHP 119
+++ + ++ GDG + II +L +++ P
Sbjct: 68 IVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDP 107
>gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]
Length = 710
Score = 34.7 bits (78), Expect = 0.23
Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 204 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNP--RIVLLDSSL--EYKKGESQTDIEIT 259
+PG SCV G + V++ + + ++N RIVL++ L Y+ I
Sbjct: 320 LPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIEGDLTENYRHLGFNKSANIK 379
Query: 260 REEDFTRILQ--MEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRK 317
D R+ + EE + + + +IQ K ++V+ + +S+ + + I V
Sbjct: 380 TVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSERLIEKCINSKRLVIGSVNG 439
Query: 318 TDNNRIARACGARIVSRPEELREDDVGTG 346
+ A A GA V+ ++ ED VG G
Sbjct: 440 SVMQAFAEAAGAVQVAYITQVNEDCVGDG 468
>gi|14251207 MOV10-like 1 [Homo sapiens]
Length = 1211
Score = 31.6 bits (70), Expect = 1.9
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 131 DDMISTLKKISIPVDISDSDMMLNIINSSITTKAIS-RWSSLACNIALDAVKMVQFEENG 189
D M + +S+P + SD +N +NS K SSL N + ENG
Sbjct: 326 DQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQMSESSLVNNRGISPGDCTCKGENG 385
Query: 190 RKEIDIKKYARVEKIPGGII 209
K+ + + E PGG++
Sbjct: 386 EKDNILSRKQMTEPEPGGLV 405
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 253 QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISD-LAQHYLMRANITA 311
+ D+EI EE + LQ+E+E +QL + + +++ + E + D LAQ M + + A
Sbjct: 215 RNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEA 274
Query: 312 IRRVRKTDNNRI 323
+ R+ ++
Sbjct: 275 EKLQREVQEAQV 286
>gi|10190716 spindle pole body component 25 [Homo sapiens]
Length = 224
Score = 31.6 bits (70), Expect = 1.9
Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 16/130 (12%)
Query: 244 SLEYKKGESQTDIEITREEDFTR---ILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300
S++ K+ E ++ + + +R ++Q +++ + +L ++ K ++ + I DL
Sbjct: 48 SVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLK 107
Query: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360
+ Y + I K + R+ R + + +L +D +G LEI+KI E
Sbjct: 108 EEYSRKKE--TISTANKANAERLKR------LQKSADLYKDRLG-----LEIRKIYGEKL 154
Query: 361 TFITDCKDPK 370
FI DPK
Sbjct: 155 QFIFTNIDPK 164
>gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens]
Length = 1660
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/91 (21%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 5 RPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGN 64
R +LVL + +R S G + I R G +M + + + T+D
Sbjct: 418 RNILVLGNSFRRRSSTFTLKGQAKKRFNLLGIKR---GTSETQRMYMKHLRTQMKTHDAE 474
Query: 65 AILREIQVQHPAAKSMIEISRTQDEEVGDGT 95
++L+ ++ + + S TQ+ E G G+
Sbjct: 475 SVLKHLEACSSVQRVCVTTSETQEAEQGQGS 505
>gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens]
Length = 1815
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/91 (21%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 5 RPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGN 64
R +LVL + +R S G + I R G +M + + + T+D
Sbjct: 418 RNILVLGNSFRRRSSTFTLKGQAKKRFNLLGIKR---GTSETQRMYMKHLRTQMKTHDAE 474
Query: 65 AILREIQVQHPAAKSMIEISRTQDEEVGDGT 95
++L+ ++ + + S TQ+ E G G+
Sbjct: 475 SVLKHLEACSSVQRVCVTTSETQEAEQGQGS 505
>gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens]
Length = 2248
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/91 (21%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 5 RPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGN 64
R +LVL + +R S G + I R G +M + + + T+D
Sbjct: 418 RNILVLGNSFRRRSSTFTLKGQAKKRFNLLGIKR---GTSETQRMYMKHLRTQMKTHDAE 474
Query: 65 AILREIQVQHPAAKSMIEISRTQDEEVGDGT 95
++L+ ++ + + S TQ+ E G G+
Sbjct: 475 SVLKHLEACSSVQRVCVTTSETQEAEQGQGS 505
>gi|11968182 ribosomal protein S18 [Homo sapiens]
Length = 152
Score = 31.2 bits (69), Expect = 2.5
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 309 ITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIK---KIGDEYFTFITD 365
ITAI+ V + + + R + R EL ED+V +++ KI D + D
Sbjct: 30 ITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKD 89
Query: 366 CKDPKACTILLRGASKEILSEVER 389
KD K +L G ++ ++ER
Sbjct: 90 VKDGKYSQVLANGLDNKLREDLER 113
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 30.4 bits (67), Expect = 4.3
Identities = 18/90 (20%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 195 IKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQT 254
++K+ K+ G I+ V R K + + + +K P+ ++ ++ + KG +++
Sbjct: 291 LRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTES 350
Query: 255 DIEITREEDFTRILQMEEEYIQQLCEDIIQ 284
T +ED L++ ++ I ++ E +I+
Sbjct: 351 CNTTTEDED----LKVRKQEIIKITEQLIE 376
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,741,651
Number of Sequences: 37866
Number of extensions: 753470
Number of successful extensions: 2089
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2017
Number of HSP's gapped (non-prelim): 36
length of query: 545
length of database: 18,247,518
effective HSP length: 107
effective length of query: 438
effective length of database: 14,195,856
effective search space: 6217784928
effective search space used: 6217784928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.