Guide to the Human Genome
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Search of human proteins with 63079709

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|63079709 apolipoprotein AV [Homo sapiens]
         (366 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|63079709 apolipoprotein AV [Homo sapiens]                          727   0.0  
gi|71773110 apolipoprotein A-IV precursor [Homo sapiens]              125   5e-29
gi|4557321 apolipoprotein A-I preproprotein [Homo sapiens]             70   2e-12
gi|4557325 apolipoprotein E precursor [Homo sapiens]                   51   1e-06
gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-l...    44   2e-04
gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-l...    44   2e-04
gi|16262452 cingulin [Homo sapiens]                                    44   3e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           43   4e-04
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           43   4e-04
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           43   4e-04
gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein...    43   4e-04
gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein...    43   4e-04
gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein...    43   4e-04
gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-l...    43   4e-04
gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-l...    43   4e-04
gi|195947367 golgi autoantigen, golgin subfamily a, 8B [Homo sap...    43   5e-04
gi|31083099 golgi autoantigen, golgin subfamily a, 8A [Homo sapi...    43   5e-04
gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-l...    42   0.001
gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-l...    42   0.001
gi|21735548 centrosomal protein 2 [Homo sapiens]                       40   0.004
gi|38044112 restin isoform b [Homo sapiens]                            40   0.004
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    40   0.004
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         40   0.004
gi|126723390 ankyrin repeat domain 24 [Homo sapiens]                   39   0.006
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        39   0.007
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        39   0.007
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         39   0.007
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         39   0.007
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         39   0.007
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         39   0.007

>gi|63079709 apolipoprotein AV [Homo sapiens]
          Length = 366

 Score =  727 bits (1877), Expect = 0.0
 Identities = 366/366 (100%), Positives = 366/366 (100%)

Query: 1   MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSL 60
           MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSL
Sbjct: 1   MASMAAVLTWALALLSAFSATQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSL 60

Query: 61  EQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGW 120
           EQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGW
Sbjct: 61  EQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGW 120

Query: 121 NLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRV 180
           NLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRV
Sbjct: 121 NLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSRV 180

Query: 181 VHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAK 240
           VHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAK
Sbjct: 181 VHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAK 240

Query: 241 ALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFT 300
           ALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFT
Sbjct: 241 ALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFT 300

Query: 301 RAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGH 360
           RAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGH
Sbjct: 301 RAIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHDQGH 360

Query: 361 SHLGDP 366
           SHLGDP
Sbjct: 361 SHLGDP 366


>gi|71773110 apolipoprotein A-IV precursor [Homo sapiens]
          Length = 396

 Score =  125 bits (315), Expect = 5e-29
 Identities = 96/338 (28%), Positives = 168/338 (49%), Gaps = 18/338 (5%)

Query: 5   AAVLTWALALLSA----FSATQARKGFWDYFSQTSGD-KGRVEQIHQQKMARE-PATLKD 58
           A VLT AL  ++      SA Q     WDYFSQ S + K  VE + + ++ ++  A  +D
Sbjct: 5   AVVLTLALVAVAGARAEVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQD 64

Query: 59  SLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELV 118
            L +         +KL P +     RL +D   ++ ++ +ELEE++ARL P+  E  + +
Sbjct: 65  KLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKI 124

Query: 119 GWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQ---- 174
           G NL  L+Q+L+PY   L  QV+ + ++L+ QL    +  +  L    D   A L+    
Sbjct: 125 GDNLRELQQRLEPYADQLRTQVSTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHAD 184

Query: 175 GLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRK 234
            L++++  +    K    PYA+     I + V+EL RS+AP+A  +  +L+  ++ L+ +
Sbjct: 185 ELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQ 244

Query: 235 LTLKAKALHARIQQNLDQLREELSRAFAGT-----GTEEGAGPDPQMLSEEVRQRLQAFR 289
           +   A+ L ARI  + ++LR+ L+           G  EG       L   + Q+++ FR
Sbjct: 245 MKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFR 304

Query: 290 QDTYLQIAAFTRAIDQETEEVQQQLAP---PPPGHSAF 324
           +        F +A+ Q+ E+++Q+L P      GH +F
Sbjct: 305 RRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSF 342



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 20/87 (22%), Positives = 47/87 (54%), Gaps = 7/87 (8%)

Query: 72  EKLRPLSGSEAPRLPQDPVGMRRQLQE-------ELEEVKARLQPYMAEAHELVGWNLEG 124
           ++L PL+      L  +  G+++ L E       ++EE + R++PY    ++ +   +E 
Sbjct: 265 QRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQ 324

Query: 125 LRQQLKPYTMDLMEQVALRVQELQEQL 151
           LRQ+L P+  D+   ++   ++L++++
Sbjct: 325 LRQKLGPHAGDVEGHLSFLEKDLRDKV 351


>gi|4557321 apolipoprotein A-I preproprotein [Homo sapiens]
          Length = 267

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 60/270 (22%), Positives = 120/270 (44%), Gaps = 23/270 (8%)

Query: 5   AAVLTWALALLSAFSAT------QARKGFWD-------YFSQTSGDKGR--VEQIHQQKM 49
           AAVLT A+  L+   A       +  +  WD        +     D GR  V Q     +
Sbjct: 3   AAVLTLAVLFLTGSQARHFWQQDEPPQSPWDRVKDLATVYVDVLKDSGRDYVSQFEGSAL 62

Query: 50  ARE-PATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQ 108
            ++    L D+ +   +  +K  E+L P++      L ++  G+R+++ ++LEEVKA++Q
Sbjct: 63  GKQLNLKLLDNWDSVTSTFSKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQ 122

Query: 109 PYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDE 168
           PY+ +  +     +E  RQ+++P   +L E    ++ ELQE+L  +GE+ +       D 
Sbjct: 123 PYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMR-------DR 175

Query: 169 AWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCV 228
           A A +  L++ +  ++   ++      E+L    G  + E H     H      +    +
Sbjct: 176 ARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAKPAL 235

Query: 229 QVLSRKLTLKAKALHARIQQNLDQLREELS 258
           + L + L    ++        L++  ++L+
Sbjct: 236 EDLRQGLLPVLESFKVSFLSALEEYTKKLN 265


>gi|4557325 apolipoprotein E precursor [Homo sapiens]
          Length = 317

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 56/250 (22%), Positives = 108/250 (43%), Gaps = 17/250 (6%)

Query: 27  FWDYFS--QTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPR 84
           FWDY    QT  ++ + E +  Q      A + +++++     ++  E+L P++     R
Sbjct: 51  FWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRAR 110

Query: 85  LPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
           L ++    + +L  ++E+V  RL  Y  E   ++G + E LR +L  +   L +++    
Sbjct: 111 LSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRKLRKRLLRDA 170

Query: 145 QELQEQLRVVGEDTKAQLLGGVDEAWALLQGL--QSRVVHHT------GRFKELFHPYAE 196
            +LQ++L V     +     G+      L  L  Q RV   T         +E    + E
Sbjct: 171 DDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGE 230

Query: 197 SL---VSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQL 253
            L   +  +G   ++    V        A+L    Q    ++ L+A+A  AR++   + L
Sbjct: 231 RLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ----QIRLQAEAFQARLKSWFEPL 286

Query: 254 REELSRAFAG 263
            E++ R +AG
Sbjct: 287 VEDMQRQWAG 296



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 44/196 (22%), Positives = 85/196 (43%), Gaps = 23/196 (11%)

Query: 127 QQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALL----QGLQSRVVH 182
           Q+L+    + M+++     EL+EQL  V E+T+A+L   +  A A L    + +  R+V 
Sbjct: 76  QELRALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQ 135

Query: 183 HTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKAL 242
           + G  + +           +G+  +EL   +A H      RL R    L ++L +     
Sbjct: 136 YRGEVQAM-----------LGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGA 184

Query: 243 HARIQQNLDQLREELSRAFAGTGTEEG---AGPDPQMLSEEVRQRLQAFRQDTYLQIAAF 299
               ++ L  +RE L     G   E+G   A     +  + +++R QA+ +    ++   
Sbjct: 185 REGAERGLSAIRERL-----GPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEM 239

Query: 300 TRAIDQETEEVQQQLA 315
                   +EV++Q+A
Sbjct: 240 GSRTRDRLDEVKEQVA 255


>gi|169208036 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 2 [Homo sapiens]
          Length = 601

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 11/138 (7%)

Query: 29  DYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQD 88
           +Y     G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +
Sbjct: 239 EYSEHLKGERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPE 297

Query: 89  PVGM-----RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALR 143
           P  +      + L++ELE V   LQ  + +        +  L Q+ +    +  E++  +
Sbjct: 298 PPAVPSEVELQHLRKELERVAGELQAQVKK-----NQRISLLNQRQEERIQEQEERLRKQ 352

Query: 144 VQELQEQLRVVGEDTKAQ 161
            + +QEQ + + +  K Q
Sbjct: 353 EERIQEQHKSLQQLAKPQ 370


>gi|239745147 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 630

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 11/138 (7%)

Query: 29  DYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQD 88
           +Y     G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +
Sbjct: 240 EYSEHLKGERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPE 298

Query: 89  PVGM-----RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALR 143
           P  +      + L++ELE V   LQ  + +        +  L Q+ +    +  E++  +
Sbjct: 299 PPAVPSEVELQHLRKELERVAGELQAQVKK-----NQRISLLNQRQEERIQEQEERLRKQ 353

Query: 144 VQELQEQLRVVGEDTKAQ 161
            + +QEQ + + +  K Q
Sbjct: 354 EERIQEQHKSLQQLAKPQ 371


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 81/356 (22%), Positives = 152/356 (42%), Gaps = 49/356 (13%)

Query: 21  TQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGS 80
           T    G W    Q + +  R  +    ++  E   +++ L + +  + + LE+ R  +G 
Sbjct: 564 TSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARASAGD 623

Query: 81  EAPRLPQDPVGMRRQL---QEELEEVKARLQPYMAEAHELVGWNLEG-LRQQLKPYTMDL 136
                 +    ++++L   QEEL+E++A  Q     + E+ G + +  L +QL    ++ 
Sbjct: 624 T-----RQVEVLKKELLRTQEELKELQAERQ-----SQEVAGRHRDRELEKQLAVLRVEA 673

Query: 137 -----MEQVALRVQELQEQLRVVGED-TKAQLLGGVDEAWALLQGLQSRVVHHTGRFKEL 190
                +E+  L++Q+  +QLR   E+ +KA++   V EA A + G +   V  T R  + 
Sbjct: 674 DRGRELEEQNLQLQKTLQQLRQDCEEASKAKM---VAEAEATVLGQRRAAVETTLRETQE 730

Query: 191 FHPYAESLVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQN- 249
            +      + G+ + ++E  R +     A  ARL   +Q L  +     +AL+A  ++  
Sbjct: 731 ENDEFRRRILGLEQQLKET-RGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEG 789

Query: 250 --------LDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTR 301
                   L+   EE  R  A  G E+      + L EE +QR    R    L+     R
Sbjct: 790 SLAAAKRALEARLEEAQRGLARLGQEQQTLN--RALEEEGKQREVLRRGKAELEEQK--R 845

Query: 302 AIDQETEEVQQQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSLHD 357
            +D+  + + ++L            E    DS + L +LQA+L+D  E     + D
Sbjct: 846 LLDRTVDRLNKEL------------EKIGEDSKQALQQLQAQLEDYKEKARREVAD 889



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 28/132 (21%), Positives = 63/132 (47%), Gaps = 14/132 (10%)

Query: 57  KDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHE 116
           K  L++ ++ +NK LEK+   S     +L       + + + E+ + + + + + +EA +
Sbjct: 844 KRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEK 903

Query: 117 LVGW------NLEGLRQQLKPYTMDL------MEQVALRVQELQEQL--RVVGEDTKAQL 162
             G        ++ LRQ L+    +        E +A R+Q L+++   +   +D +A+ 
Sbjct: 904 TSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDDRARQ 963

Query: 163 LGGVDEAWALLQ 174
           L G++E  + L+
Sbjct: 964 LKGLEEKVSRLE 975


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 87/340 (25%), Positives = 136/340 (40%), Gaps = 52/340 (15%)

Query: 39   GRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQE 98
            G  EQ+ ++  ARE A       ++L      L + R     EA  L       RR+   
Sbjct: 1372 GLREQLEEEAAARERAG------RELQTAQAQLSEWRRRQEEEAGALEAGEEA-RRRAAR 1424

Query: 99   ELEEVKARLQPYMAEAHELVGWNLEG---LRQQLKPYTMDLMEQVAL------------- 142
            E E +  RL    AE  E V     G   L+Q+L   TMDL +Q  L             
Sbjct: 1425 EAEALTQRL----AEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1480

Query: 143  -RVQELQEQLRVVGEDTKAQLLGGVDEAWAL--LQGLQSR--VVHHTGRFKELFHPYAES 197
               +E    LR V E  +A+  G   EA AL   + L+          R         E+
Sbjct: 1481 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1540

Query: 198  LVSG---IGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLR 254
            L+S    +G+ V EL R+    A  +   L   V  L  +LT  A+    R++  +  L+
Sbjct: 1541 LLSSKDDVGKSVHELERACRV-AEQAANDLRAQVTELEDELTA-AEDAKLRLEVTVQALK 1598

Query: 255  EELSRAFAG---TGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQ 311
             +  R   G    G E       Q+   EV +  +  R+   L +AA  + ++ E EE++
Sbjct: 1599 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE--RKQRTLAVAA-RKKLEGELEELK 1655

Query: 312  QQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDI 351
             Q+A    G         + ++ K L K+QA++ +LW ++
Sbjct: 1656 AQMASAGQG---------KEEAVKQLRKMQAQMKELWREV 1686



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 61/276 (22%), Positives = 118/276 (42%), Gaps = 52/276 (18%)

Query: 40   RVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM---RRQL 96
            R  Q   +++ RE    + S E+  +   +  ++L+ L  +E  RL ++       RRQ 
Sbjct: 1673 RKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE-AEVLRLQEELAASDRARRQA 1731

Query: 97   QEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGE 156
            Q++ +E+          A E+   NL       K   ++   Q+  R+ +L+E+L    E
Sbjct: 1732 QQDRDEM----------ADEVANGNLS------KAAILEEKRQLEGRLGQLEEELEE--E 1773

Query: 157  DTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPH 216
             + ++LL   D    LL  ++S     +   +  F   AES    + R +QEL   +   
Sbjct: 1774 QSNSELLN--DRYRKLLLQVESLTTELSA--ERSFSAKAESGRQQLERQIQELRGRLGEE 1829

Query: 217  APASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQM 276
               + AR          K+T+   AL +++ Q  +QL +E         T E      ++
Sbjct: 1830 DAGARAR---------HKMTI--AALESKLAQAEEQLEQE---------TRE------RI 1863

Query: 277  LSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQ 312
            LS ++ +R +   ++  LQ+    R  DQ  +++++
Sbjct: 1864 LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEK 1899



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 69/324 (21%), Positives = 129/324 (39%), Gaps = 51/324 (15%)

Query: 48   KMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARL 107
            K+++E   L+D L +  +   +  EK++ L+             +R + +  + +++ RL
Sbjct: 1021 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK------------LRLKYEATIADMEDRL 1068

Query: 108  QPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVA---LRVQELQEQLRVVGEDTKAQLLG 164
            +       EL     E L+++L   + +L EQ+     R +EL+ QL    E+ +A L  
Sbjct: 1069 RKEEKGRQEL-----EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123

Query: 165  GVDEAWALLQGLQS--------RVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPH 216
              DE  A  Q L+S                 + +    AE     +G  ++ L   +   
Sbjct: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183

Query: 217  APASPA----RLSRCVQVLSRKLTLK---------AKALHARIQQNLDQLREELSRAFAG 263
              ++ A    R  R  +V   K TL+          + L  R  Q L +L E+L +A  G
Sbjct: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243

Query: 264  TGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSA 323
             G  E      +    E+R  L +  Q    +     R ++ + +EVQ +         A
Sbjct: 1244 KGAWEKTRLALEAEVSELRAELSSL-QTARQEGEQRRRRLELQLQEVQGR---------A 1293

Query: 324  FAPEFQQTDSGKVLSKLQARLDDL 347
               E  + ++ + L + QA L+++
Sbjct: 1294 GDGERARAEAAEKLQRAQAELENV 1317


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 87/340 (25%), Positives = 136/340 (40%), Gaps = 52/340 (15%)

Query: 39   GRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQE 98
            G  EQ+ ++  ARE A       ++L      L + R     EA  L       RR+   
Sbjct: 1364 GLREQLEEEAAARERAG------RELQTAQAQLSEWRRRQEEEAGALEAGEEA-RRRAAR 1416

Query: 99   ELEEVKARLQPYMAEAHELVGWNLEG---LRQQLKPYTMDLMEQVAL------------- 142
            E E +  RL    AE  E V     G   L+Q+L   TMDL +Q  L             
Sbjct: 1417 EAEALTQRL----AEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1472

Query: 143  -RVQELQEQLRVVGEDTKAQLLGGVDEAWAL--LQGLQSR--VVHHTGRFKELFHPYAES 197
               +E    LR V E  +A+  G   EA AL   + L+          R         E+
Sbjct: 1473 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1532

Query: 198  LVSG---IGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLR 254
            L+S    +G+ V EL R+    A  +   L   V  L  +LT  A+    R++  +  L+
Sbjct: 1533 LLSSKDDVGKSVHELERACRV-AEQAANDLRAQVTELEDELTA-AEDAKLRLEVTVQALK 1590

Query: 255  EELSRAFAG---TGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQ 311
             +  R   G    G E       Q+   EV +  +  R+   L +AA  + ++ E EE++
Sbjct: 1591 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE--RKQRTLAVAA-RKKLEGELEELK 1647

Query: 312  QQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDI 351
             Q+A    G         + ++ K L K+QA++ +LW ++
Sbjct: 1648 AQMASAGQG---------KEEAVKQLRKMQAQMKELWREV 1678



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 61/276 (22%), Positives = 118/276 (42%), Gaps = 52/276 (18%)

Query: 40   RVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM---RRQL 96
            R  Q   +++ RE    + S E+  +   +  ++L+ L  +E  RL ++       RRQ 
Sbjct: 1665 RKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE-AEVLRLQEELAASDRARRQA 1723

Query: 97   QEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGE 156
            Q++ +E+          A E+   NL       K   ++   Q+  R+ +L+E+L    E
Sbjct: 1724 QQDRDEM----------ADEVANGNLS------KAAILEEKRQLEGRLGQLEEELEE--E 1765

Query: 157  DTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPH 216
             + ++LL   D    LL  ++S     +   +  F   AES    + R +QEL   +   
Sbjct: 1766 QSNSELLN--DRYRKLLLQVESLTTELSA--ERSFSAKAESGRQQLERQIQELRGRLGEE 1821

Query: 217  APASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQM 276
               + AR          K+T+   AL +++ Q  +QL +E         T E      ++
Sbjct: 1822 DAGARAR---------HKMTI--AALESKLAQAEEQLEQE---------TRE------RI 1855

Query: 277  LSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQ 312
            LS ++ +R +   ++  LQ+    R  DQ  +++++
Sbjct: 1856 LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEK 1891



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 69/324 (21%), Positives = 129/324 (39%), Gaps = 51/324 (15%)

Query: 48   KMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARL 107
            K+++E   L+D L +  +   +  EK++ L+             +R + +  + +++ RL
Sbjct: 1013 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK------------LRLKYEATIADMEDRL 1060

Query: 108  QPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVA---LRVQELQEQLRVVGEDTKAQLLG 164
            +       EL     E L+++L   + +L EQ+     R +EL+ QL    E+ +A L  
Sbjct: 1061 RKEEKGRQEL-----EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1115

Query: 165  GVDEAWALLQGLQS--------RVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPH 216
              DE  A  Q L+S                 + +    AE     +G  ++ L   +   
Sbjct: 1116 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1175

Query: 217  APASPA----RLSRCVQVLSRKLTLK---------AKALHARIQQNLDQLREELSRAFAG 263
              ++ A    R  R  +V   K TL+          + L  R  Q L +L E+L +A  G
Sbjct: 1176 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1235

Query: 264  TGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSA 323
             G  E      +    E+R  L +  Q    +     R ++ + +EVQ +         A
Sbjct: 1236 KGAWEKTRLALEAEVSELRAELSSL-QTARQEGEQRRRRLELQLQEVQGR---------A 1285

Query: 324  FAPEFQQTDSGKVLSKLQARLDDL 347
               E  + ++ + L + QA L+++
Sbjct: 1286 GDGERARAEAAEKLQRAQAELENV 1309


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 87/340 (25%), Positives = 136/340 (40%), Gaps = 52/340 (15%)

Query: 39   GRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQE 98
            G  EQ+ ++  ARE A       ++L      L + R     EA  L       RR+   
Sbjct: 1405 GLREQLEEEAAARERAG------RELQTAQAQLSEWRRRQEEEAGALEAGEEA-RRRAAR 1457

Query: 99   ELEEVKARLQPYMAEAHELVGWNLEG---LRQQLKPYTMDLMEQVAL------------- 142
            E E +  RL    AE  E V     G   L+Q+L   TMDL +Q  L             
Sbjct: 1458 EAEALTQRL----AEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1513

Query: 143  -RVQELQEQLRVVGEDTKAQLLGGVDEAWAL--LQGLQSR--VVHHTGRFKELFHPYAES 197
               +E    LR V E  +A+  G   EA AL   + L+          R         E+
Sbjct: 1514 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1573

Query: 198  LVSG---IGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLR 254
            L+S    +G+ V EL R+    A  +   L   V  L  +LT  A+    R++  +  L+
Sbjct: 1574 LLSSKDDVGKSVHELERACRV-AEQAANDLRAQVTELEDELTA-AEDAKLRLEVTVQALK 1631

Query: 255  EELSRAFAG---TGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQ 311
             +  R   G    G E       Q+   EV +  +  R+   L +AA  + ++ E EE++
Sbjct: 1632 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEE--RKQRTLAVAA-RKKLEGELEELK 1688

Query: 312  QQLAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDI 351
             Q+A    G         + ++ K L K+QA++ +LW ++
Sbjct: 1689 AQMASAGQG---------KEEAVKQLRKMQAQMKELWREV 1719



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 61/276 (22%), Positives = 118/276 (42%), Gaps = 52/276 (18%)

Query: 40   RVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM---RRQL 96
            R  Q   +++ RE    + S E+  +   +  ++L+ L  +E  RL ++       RRQ 
Sbjct: 1706 RKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE-AEVLRLQEELAASDRARRQA 1764

Query: 97   QEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGE 156
            Q++ +E+          A E+   NL       K   ++   Q+  R+ +L+E+L    E
Sbjct: 1765 QQDRDEM----------ADEVANGNLS------KAAILEEKRQLEGRLGQLEEELEE--E 1806

Query: 157  DTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPH 216
             + ++LL   D    LL  ++S     +   +  F   AES    + R +QEL   +   
Sbjct: 1807 QSNSELLN--DRYRKLLLQVESLTTELSA--ERSFSAKAESGRQQLERQIQELRGRLGEE 1862

Query: 217  APASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQM 276
               + AR          K+T+   AL +++ Q  +QL +E         T E      ++
Sbjct: 1863 DAGARAR---------HKMTI--AALESKLAQAEEQLEQE---------TRE------RI 1896

Query: 277  LSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQ 312
            LS ++ +R +   ++  LQ+    R  DQ  +++++
Sbjct: 1897 LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEK 1932



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 69/324 (21%), Positives = 129/324 (39%), Gaps = 51/324 (15%)

Query: 48   KMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARL 107
            K+++E   L+D L +  +   +  EK++ L+             +R + +  + +++ RL
Sbjct: 1054 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK------------LRLKYEATIADMEDRL 1101

Query: 108  QPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVA---LRVQELQEQLRVVGEDTKAQLLG 164
            +       EL     E L+++L   + +L EQ+     R +EL+ QL    E+ +A L  
Sbjct: 1102 RKEEKGRQEL-----EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1156

Query: 165  GVDEAWALLQGLQS--------RVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPH 216
              DE  A  Q L+S                 + +    AE     +G  ++ L   +   
Sbjct: 1157 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1216

Query: 217  APASPA----RLSRCVQVLSRKLTLK---------AKALHARIQQNLDQLREELSRAFAG 263
              ++ A    R  R  +V   K TL+          + L  R  Q L +L E+L +A  G
Sbjct: 1217 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1276

Query: 264  TGTEEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSA 323
             G  E      +    E+R  L +  Q    +     R ++ + +EVQ +         A
Sbjct: 1277 KGAWEKTRLALEAEVSELRAELSSL-QTARQEGEQRRRRLELQLQEVQGR---------A 1326

Query: 324  FAPEFQQTDSGKVLSKLQARLDDL 347
               E  + ++ + L + QA L+++
Sbjct: 1327 GDGERARAEAAEKLQRAQAELENV 1350


>gi|239745114 PREDICTED: Golgin subfamily A member 8-like protein 3
           [Homo sapiens]
          Length = 580

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 11/138 (7%)

Query: 29  DYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQD 88
           +Y     G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +
Sbjct: 211 EYSEHLKGERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPE 269

Query: 89  PVGM-----RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALR 143
           P  +      + L++ELE V   LQ  +          +  L Q+ +    +  E++  +
Sbjct: 270 PPAVPSEVELQHLRKELERVAGELQAQVKN-----NQRISLLNQRQEERIREQEERLRKQ 324

Query: 144 VQELQEQLRVVGEDTKAQ 161
            + +QEQ + + +  K Q
Sbjct: 325 EERIQEQHKSLQQLAKPQ 342


>gi|169208014 PREDICTED: Golgin subfamily A member 8-like protein 3
           isoform 2 [Homo sapiens]
          Length = 602

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 11/138 (7%)

Query: 29  DYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQD 88
           +Y     G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +
Sbjct: 239 EYSEHLKGERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPE 297

Query: 89  PVGM-----RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALR 143
           P  +      + L++ELE V   LQ  +          +  L Q+ +    +  E++  +
Sbjct: 298 PPAVPSEVELQHLRKELERVAGELQAQVKN-----NQRISLLNQRQEERIREQEERLRKQ 352

Query: 144 VQELQEQLRVVGEDTKAQ 161
            + +QEQ + + +  K Q
Sbjct: 353 EERIQEQHKSLQQLAKPQ 370


>gi|239745111 PREDICTED: Golgin subfamily A member 8-like protein 3
           isoform 1 [Homo sapiens]
          Length = 632

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 11/138 (7%)

Query: 29  DYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQD 88
           +Y     G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +
Sbjct: 240 EYSEHLKGERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPE 298

Query: 89  PVGM-----RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALR 143
           P  +      + L++ELE V   LQ  +          +  L Q+ +    +  E++  +
Sbjct: 299 PPAVPSEVELQHLRKELERVAGELQAQVKN-----NQRISLLNQRQEERIREQEERLRKQ 353

Query: 144 VQELQEQLRVVGEDTKAQ 161
            + +QEQ + + +  K Q
Sbjct: 354 EERIQEQHKSLQQLAKPQ 371


>gi|169208517 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 2 [Homo sapiens]
          Length = 602

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 11/138 (7%)

Query: 29  DYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQD 88
           +Y     G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +
Sbjct: 239 EYSEHLKGERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPE 297

Query: 89  PVGM-----RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALR 143
           P  +      + L++ELE V   LQ  +          +  L Q+ +    +  E++  +
Sbjct: 298 PPAVPSEVELQHLRKELERVAGELQAQVKN-----NQRISLLNQRQEERIREQEERLRKQ 352

Query: 144 VQELQEQLRVVGEDTKAQ 161
            + +QEQ + + +  K Q
Sbjct: 353 EERIQEQHKSLQQLAKPQ 370


>gi|239745099 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 632

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/138 (24%), Positives = 62/138 (44%), Gaps = 11/138 (7%)

Query: 29  DYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQD 88
           +Y     G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +
Sbjct: 240 EYSEHLKGERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPE 298

Query: 89  PVGM-----RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALR 143
           P  +      + L++ELE V   LQ  +          +  L Q+ +    +  E++  +
Sbjct: 299 PPAVPSEVELQHLRKELERVAGELQAQVKN-----NQRISLLNQRQEERIREQEERLRKQ 353

Query: 144 VQELQEQLRVVGEDTKAQ 161
            + +QEQ + + +  K Q
Sbjct: 354 EERIQEQHKSLQQLAKPQ 371


>gi|195947367 golgi autoantigen, golgin subfamily a, 8B [Homo
           sapiens]
          Length = 603

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 8/132 (6%)

Query: 30  YFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDP 89
           Y  Q  G++ + +Q   +KM++E  TLK+  + D + + +    L  L    A  LP D 
Sbjct: 233 YAEQIKGERAQWQQ-RMRKMSQEVCTLKEEKKHDTHRVEELERSLSRLKNQMAEPLPPDA 291

Query: 90  VGMR-----RQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
             +      + L++ELE V   LQ    E ++ +     G +++L+     L EQ   R+
Sbjct: 292 PAVSSEVELQDLRKELERVAGELQA-QVENNQCISLLNRGQKERLREQEERLQEQQE-RL 349

Query: 145 QELQEQLRVVGE 156
           +E +++L+ + E
Sbjct: 350 REREKRLQQLAE 361



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 64/302 (21%), Positives = 116/302 (38%), Gaps = 60/302 (19%)

Query: 47  QKMAREPATLKDSLEQDLNNMNKFLEKLRPLSG------SEAPRLPQDPVGMRRQL---Q 97
           + + ++   ++  LE++    N+  +  R L G      +E  +L  D   M+  L   +
Sbjct: 93  KSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEKKKLNTDLYHMKHSLRYFE 152

Query: 98  EELEEVKARLQPYMAEAHELVGWNLEGLR--QQLKP--------------YTMDLMEQVA 141
           EE +++  RLQ       EL  W+L  +   Q+ KP                  + EQ+ 
Sbjct: 153 EESKDLAGRLQRSSQRIGELE-WSLCAVAATQKKKPDGFSSRSKALLKRQLEQSIREQIL 211

Query: 142 LR--VQELQEQLRVVG--EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAES 197
           L+  V +L+E L+ V    D  A+ + G    W       S+ V      K+      E 
Sbjct: 212 LKGHVTQLKESLKEVQLERDQYAEQIKGERAQWQQRMRKMSQEVCTLKEEKKHDTHRVEE 271

Query: 198 LVSGIGRHVQELHRSVAPHAPASPARL----------------------SRCVQVLSRKL 235
           L   + R   ++   + P APA  + +                      ++C+ +L+R  
Sbjct: 272 LERSLSRLKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQAQVENNQCISLLNRGQ 331

Query: 236 TLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP--DPQMLSEEVRQRLQAFRQDTY 293
             + +    R+Q+  ++LRE   R       ++ A P  D + L  E +  LQ  +Q   
Sbjct: 332 KERLREQEERLQEQQERLREREKR------LQQLAEPQSDLEELKHENKSALQLEQQVKE 385

Query: 294 LQ 295
           LQ
Sbjct: 386 LQ 387


>gi|31083099 golgi autoantigen, golgin subfamily a, 8A [Homo
           sapiens]
          Length = 603

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 8/132 (6%)

Query: 30  YFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDP 89
           Y  Q  G++ + +Q   +KM++E  TLK+  + D + + +    L  L    A  LP D 
Sbjct: 233 YAEQIKGERAQWQQ-RMRKMSQEVCTLKEEKKHDTHRVEELERSLSRLKNQMAEPLPPDA 291

Query: 90  VGMR-----RQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
             +      + L++ELE V   LQ    E ++ +     G +++L+     L EQ   R+
Sbjct: 292 PAVSSEVELQDLRKELERVAGELQA-QVENNQCISLLNRGQKERLREQEERLQEQQE-RL 349

Query: 145 QELQEQLRVVGE 156
           +E +++L+ + E
Sbjct: 350 REREKRLQQLAE 361



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 64/302 (21%), Positives = 116/302 (38%), Gaps = 60/302 (19%)

Query: 47  QKMAREPATLKDSLEQDLNNMNKFLEKLRPLSG------SEAPRLPQDPVGMRRQL---Q 97
           + + ++   ++  LE++    N+  +  R L G      +E  +L  D   M+  L   +
Sbjct: 93  KSLKQQKKQVEHQLEEEKKANNEKQKAERELEGQIQRLNTEKKKLNTDLYHMKHSLRYFE 152

Query: 98  EELEEVKARLQPYMAEAHELVGWNLEGLR--QQLKP--------------YTMDLMEQVA 141
           EE +++  RLQ       EL  W+L  +   Q+ KP                  + EQ+ 
Sbjct: 153 EESKDLAGRLQRSSQRIGELE-WSLCAVAATQKKKPDGFSSRSKALLKRQLEQSIREQIL 211

Query: 142 LR--VQELQEQLRVVG--EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAES 197
           L+  V +L+E L+ V    D  A+ + G    W       S+ V      K+      E 
Sbjct: 212 LKGHVTQLKESLKEVQLERDQYAEQIKGERAQWQQRMRKMSQEVCTLKEEKKHDTHRVEE 271

Query: 198 LVSGIGRHVQELHRSVAPHAPASPARL----------------------SRCVQVLSRKL 235
           L   + R   ++   + P APA  + +                      ++C+ +L+R  
Sbjct: 272 LERSLSRLKNQMAEPLPPDAPAVSSEVELQDLRKELERVAGELQAQVENNQCISLLNRGQ 331

Query: 236 TLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP--DPQMLSEEVRQRLQAFRQDTY 293
             + +    R+Q+  ++LRE   R       ++ A P  D + L  E +  LQ  +Q   
Sbjct: 332 KERLREQEERLQEQQERLREREKR------LQQLAEPQSDLEELKHENKSALQLEQQVKE 385

Query: 294 LQ 295
           LQ
Sbjct: 386 LQ 387


>gi|239745132 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 [Homo sapiens]
          Length = 602

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 11/131 (8%)

Query: 36  GDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM--- 92
           G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +P  +   
Sbjct: 246 GERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSE 304

Query: 93  --RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQ 150
              + L++ELE V   LQ  + +        +  L Q+ +    +  E++  + + +QEQ
Sbjct: 305 VELQHLRKELERVAGELQAQVKK-----NQRISLLNQRQEERIQEQEERLRKQEERIQEQ 359

Query: 151 LRVVGEDTKAQ 161
            + + +  K Q
Sbjct: 360 HKSLQQLAKPQ 370


>gi|239745130 PREDICTED: similar to Golgin subfamily A member 8-like
           protein 1 isoform 1 [Homo sapiens]
          Length = 632

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 11/131 (8%)

Query: 36  GDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGM--- 92
           G++ R +Q   +KM++E  TLK   +QD+  + K    L  L    A  LP +P  +   
Sbjct: 247 GERARWQQ-RMRKMSQEICTLKKEKQQDMRRVEKLERSLSKLKNQMAEPLPPEPPAVPSE 305

Query: 93  --RRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQ 150
              + L++ELE V   LQ  + +        +  L Q+ +    +  E++  + + +QEQ
Sbjct: 306 VELQHLRKELERVAGELQAQVKK-----NQRISLLNQRQEERIQEQEERLRKQEERIQEQ 360

Query: 151 LRVVGEDTKAQ 161
            + + +  K Q
Sbjct: 361 HKSLQQLAKPQ 371


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 76/342 (22%), Positives = 137/342 (40%), Gaps = 48/342 (14%)

Query: 45   HQQKMAREPATL---KDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELE 101
            HQQ++A+   +L   K  LE  L      +E ++  +  E  R   +    + QL+ E E
Sbjct: 869  HQQELAKALESLEREKMELEMRLKEQQTEMEAIQ--AQREEERTQAESALCQMQLETEKE 926

Query: 102  EVKARLQPYMAEAHELV--GWNLEGLRQQLKPYTMDLMEQVAL---RVQELQEQLRVVGE 156
             V   L+  +    EL      LE LRQ +K   +   E   +   ++QE Q +L+    
Sbjct: 927  RVSL-LETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAAR 985

Query: 157  DTKAQLLGGVDEAWALLQ----------GLQSRVVHHTGRFKELFHPYAESLVSGIGRHV 206
              +  L    +E+ +LLQ           L+S++V      + +     E L     R  
Sbjct: 986  QHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKL-----RET 1040

Query: 207  QELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGT 266
            QE +R +        A L+  +    ++L +  +A   R QQ L  LR+++  A    G 
Sbjct: 1041 QEYNR-IQKELEREKASLTLSLMEKEQRLLVLQEADSIR-QQELSALRQDMQEA---QGE 1095

Query: 267  EEGAGPDPQMLSEEVRQRLQAFRQD-------------TYLQIAAFTRAIDQETEEVQQQ 313
            ++      ++L +EV+++   F                T  Q+ A   A + +  ++Q +
Sbjct: 1096 QKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLR 1155

Query: 314  LAPPPPGHSAFAPEFQQTDSGKVLSKLQARLDDLWEDITHSL 355
            L        A A E Q  +     ++ QA+L  L+  +  +L
Sbjct: 1156 LRSTESQLEALAAEQQPGNQ----AQAQAQLASLYSALQQAL 1193



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 73/321 (22%), Positives = 127/321 (39%), Gaps = 59/321 (18%)

Query: 21   TQARKGFWDYFSQTSGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGS 80
            ++A++G  ++      DK +  +  QQ+   E   LKD LEQ L  +++           
Sbjct: 1717 SKAQRGSLEHMKLILRDKEKEVEC-QQEHIHELQELKDQLEQQLQGLHR----------- 1764

Query: 81   EAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQV 140
                     VG    L  + E+    LQ  + EA E      + L+ QL     +    +
Sbjct: 1765 --------KVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLD----EAQRAL 1812

Query: 141  ALRVQEL----QEQLRVVGEDTKAQ-----LLGGVDEAWALLQGLQSRVVHHTGRFKELF 191
            A R QEL    QEQ +  G++ + +     L G +++A   L+     +  H  + + L 
Sbjct: 1813 AQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRL- 1871

Query: 192  HPYAESLVSGIGRHVQ-------ELHRSVAPHAPASPARLSRCV------QVLSRKLT-- 236
                E  ++  GR VQ       +L         A  A   +C       +V +R L   
Sbjct: 1872 ----EEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDS 1927

Query: 237  -LKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAF--RQDTY 293
             L+A+A+     Q L+ LR E   + +    EE A    + L E + +   A   ++   
Sbjct: 1928 WLQAQAVLKERDQELEALRAE---SQSSRHQEEAARARAEALQEALGKAHAALQGKEQHL 1984

Query: 294  LQIAAFTRAIDQETEEVQQQL 314
            L+ A  +R+++  T  +Q  L
Sbjct: 1985 LEQAELSRSLEASTATLQASL 2005



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 10/114 (8%)

Query: 41   VEQIHQQKMAREPATLKDSLEQDLNNMNKFLEK------LRPLSGSEAPRLPQDPVGMRR 94
            V Q   Q++  +    K    Q+ N + K LE+      L  +   +   + Q+   +R 
Sbjct: 1020 VAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIR- 1078

Query: 95   QLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQ 148
              Q+EL  ++  +Q    E  EL    +E LRQ++K    D + Q A  ++EL+
Sbjct: 1079 --QQELSALRQDMQEAQGEQKELSA-QMELLRQEVKEKEADFLAQEAQLLEELE 1129


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 68/280 (24%), Positives = 118/280 (42%), Gaps = 43/280 (15%)

Query: 45  HQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVK 104
           H  ++ +E A  +D  +Q +  +   +++LR +         ++ V +  QL+EE  +V+
Sbjct: 384 HVGEIEQELALARDGHDQHVLELEAKMDQLRTM----VEAADREKVELLNQLEEEKRKVE 439

Query: 105 ARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQLLG 164
             LQ +  E   +   +LE      K   M+L + +ALRVQE+ E  R +  +  A   G
Sbjct: 440 D-LQ-FRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPA---G 494

Query: 165 GVDEAWALLQ---GLQSRV-VHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPAS 220
            VD + +LLQ    LQ ++ V  T   +E+      SL    G   +E H+        +
Sbjct: 495 DVDMSLSLLQEISSLQEKLEVTRTDHQREI-----TSLKEHFGAR-EETHQKEIKALYTA 548

Query: 221 PARLSRCVQVLSRKL--------------TLKAKALHARIQQNLDQLREELSRAFAGTGT 266
             +LS+  + L  KL                K +   A  QQ +++L+   S+   GT T
Sbjct: 549 TEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL-GTET 607

Query: 267 EEGAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQE 306
            E A         E++ +++  R D   +I       D E
Sbjct: 608 AEFA---------ELKTQIEKMRLDYQHEIENLQNQQDSE 638


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 63/295 (21%), Positives = 118/295 (40%), Gaps = 50/295 (16%)

Query: 60   LEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKARLQPYMAEAHELVG 119
            LE D   +++ L+K +     +     +D   +  Q Q++++E++AR++    E      
Sbjct: 1070 LENDKQQLDERLKK-KDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEA--- 1125

Query: 120  WNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVGEDTKAQL-LGGVDEA--WALLQGL 176
                   +  +  T       A  ++EL E+L   G  T  Q+ L    EA    L + L
Sbjct: 1126 ------ERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDL 1179

Query: 177  QSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHR--------------------SVAPH 216
            +   + H      L   +A+S V+ +G  +  L R                    S    
Sbjct: 1180 EEATLQHEAMVAALRKKHADS-VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMES 1238

Query: 217  APASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGPDPQM 276
               S A L +  + L  +L+ +A+  +  IQ++L +L  + SR      TE G       
Sbjct: 1239 VSKSKANLEKICRTLEDQLS-EARGKNEEIQRSLSELTTQKSRL----QTEAGE------ 1287

Query: 277  LSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQT 331
            LS ++ ++     +    Q++   +A  Q+TEE+++QL       +A A   Q +
Sbjct: 1288 LSRQLEEK-----ESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSS 1337


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 72/330 (21%), Positives = 133/330 (40%), Gaps = 50/330 (15%)

Query: 42  EQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLP--------------- 86
           E+ H ++  ++ ++L   L+  ++N+++  E+L   S +   RL                
Sbjct: 453 ERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNA 512

Query: 87  ------QDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLME-- 138
                 Q+  G+++Q +E+  ++   LQ    +A + +   +E L   LK     L E  
Sbjct: 513 TIQQQDQELAGLKQQAKEKQAQLAQTLQQ-QEQASQGLRHQVEQLSSSLKQKEQQLKEVA 571

Query: 139 --QVALRVQELQEQLRVVGEDTKAQLLGGVDEAWALLQGLQSR------VVHHTGRFKEL 190
             Q A R Q+  +QL    E+ +A L    D A   L+ L+        ++    +    
Sbjct: 572 EKQEATR-QDHAQQLATAAEEREASLRER-DAALKQLEALEKEKAAKLEILQQQLQVANE 629

Query: 191 FHPYAESLVSGIGRHVQELHRSVAP-HAPASPARLSRC---VQVLSRKLTLKAKALHA-- 244
               A++ V+   R   EL R V    A    AR  +     QV   +L L+++   A  
Sbjct: 630 ARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATE 689

Query: 245 --RIQQNLDQLREELSRAFAGTGTEEGAGPDPQMLSEEVRQRLQAF--RQDTYLQIAAFT 300
             R+ Q  DQL+E+L          +G+      L EE R+   A   +Q    ++ A T
Sbjct: 690 KERVAQEKDQLQEQLQALKESLKVTKGS------LEEEKRRAADALEEQQRCISELKAET 743

Query: 301 RAIDQETEEVQQQLAPPPPGHSAFAPEFQQ 330
           R++ ++ +  +++L     G        QQ
Sbjct: 744 RSLVEQHKRERKELEEERAGRKGLEARLQQ 773



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 69/326 (21%), Positives = 132/326 (40%), Gaps = 48/326 (14%)

Query: 42   EQIHQQKMAREPATLKDSL---EQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQE 98
            +++  QK+A + +TL++ +    +++  +   + K      + +  L ++P     +  E
Sbjct: 891  KEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPE 950

Query: 99   ELEEVKAR--------LQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQ 150
             LEE + R        LQ    EA ++ G  LE LR  L        E+   R Q+ +E 
Sbjct: 951  WLEEQQGRQFCSTQAALQAMEREAEQM-GNELERLRAALMESQGQQQEE---RGQQEREV 1006

Query: 151  LRVVGEDTKAQLLGGVDEAWA--LLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQE 208
             R+  E  +AQ    +++A    L   LQ+ +      F  L    A +L    G+  QE
Sbjct: 1007 ARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKD-QE 1065

Query: 209  LHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEE 268
            L            A+L        ++L          ++Q + QL+E+L++      +  
Sbjct: 1066 L------------AKLRGLEAAQIKELE--------ELRQTVKQLKEQLAKKEKEHASGS 1105

Query: 269  GAGPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEF 328
            GA  +    +E    +L+A R        A    ++Q+ ++ Q+Q        S  A   
Sbjct: 1106 GAQSEAAGRTEPTGPKLEALR--------AEVSKLEQQCQKQQEQ--ADSLERSLEAERA 1155

Query: 329  QQTDSGKVLSKLQARLDDLWEDITHS 354
             + +    L  LQ +L++  +++ HS
Sbjct: 1156 SRAERDSALETLQGQLEEKAQELGHS 1181



 Score = 30.8 bits (68), Expect = 2.0
 Identities = 73/324 (22%), Positives = 122/324 (37%), Gaps = 61/324 (18%)

Query: 47  QKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEELEEVKAR 106
           + + +E A   + L+Q L   N+  +  +  S ++A R        + +L  ++EE++A 
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQT-SVTQAQR-------EKAELSRKVEELQAC 658

Query: 107 LQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQ--VALRVQELQEQLRVVGEDTKAQLLG 164
           ++    E HE      E L  QL+       E+  VA    +LQEQL+ + E  K    G
Sbjct: 659 VETARQEQHEAQAQVAE-LELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKV-TKG 716

Query: 165 GVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRSVAPHAPASPARL 224
            ++E     +   +  +    R          SLV    R  +EL    A          
Sbjct: 717 SLEEE----KRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGR-------- 764

Query: 225 SRCVQVLSRKLTLKAKALHARIQQ-------NLDQLREELSRAFAGTGTEEGAGPDPQML 277
                          K L AR+QQ         + LR EL+ A A   T E    + + L
Sbjct: 765 ---------------KGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAES---ECEQL 806

Query: 278 SEEV---RQRLQAFRQDTYLQIAAFTR---AIDQETEEVQQQLAPPP------PGHSAFA 325
            +EV   R+R +  +Q+     A F      + +E E+ +Q+L            HS   
Sbjct: 807 VKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQ 866

Query: 326 PEFQQTDSGKVLSKLQARLDDLWE 349
              QQ +  ++ + L   L  + E
Sbjct: 867 ISRQQNELAELHANLARALQQVQE 890


>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
          Length = 1146

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 71/316 (22%), Positives = 125/316 (39%), Gaps = 64/316 (20%)

Query: 35   SGDKGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRR 94
            + + GR     + ++A  PA  +++ +         L +LR    SEA R    P    R
Sbjct: 871  AAELGRARDAAEARVAELPAACEEARQG--------LAELR--EASEALRQSVVPASEHR 920

Query: 95   QLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVV 154
            +LQEE  E++ R     +   E+V    E  R + +      +E+  +    L E  R+V
Sbjct: 921  RLQEEALELRGRA---ASLEQEVVATGKEAARLRAE------LERERVCSVALSEHERIV 971

Query: 155  G--EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFKELFHPYAESLVSGIGRHVQELHRS 212
            G  +   AQL G ++E              H     E+F    E+L     RH       
Sbjct: 972  GTLQANVAQLEGQLEELGR----------RHEKTSAEVFQVQREALFMKSERH------- 1014

Query: 213  VAPHAPASPARLSRCVQVLS--RKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGA 270
                  A+ A+L+   Q L   R    +A+   +R Q+ LD+ +E+  +      TE   
Sbjct: 1015 ------AAEAQLATAEQQLRGLRTEAERARQAQSRAQEALDKAKEKDKKI-----TE--- 1060

Query: 271  GPDPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQLAPPPPGHSAFAPEFQQ 330
                  LS+EV    +A ++           A+  + +++QQQL      HS+    ++ 
Sbjct: 1061 ------LSKEVFNLKEALKEQPAALATPEVEALRDQVKDLQQQLQEAARDHSSVVALYR- 1113

Query: 331  TDSGKVLSKLQARLDD 346
                 +L  +Q ++D+
Sbjct: 1114 ---SHLLYAIQGQMDE 1126


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 42   EQIHQQKMAREPATL--KDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEE 99
            EQ+ Q+  A + + L  KDSL Q    + +   KL  L   E  +  Q     +RQ Q++
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ-QQQ 2540

Query: 100  LEEVKARLQPYMAEAHELVGWNLEGLR------QQLKPYTMDLMEQVALRVQELQEQLRV 153
            +E+ + RL   M EA        EG+R      QQL+       E +A   Q L+EQL++
Sbjct: 2541 MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL 2600

Query: 154  VGEDTKAQL 162
            + E  +A L
Sbjct: 2601 LEEQHRAAL 2609



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 56/305 (18%), Positives = 119/305 (39%), Gaps = 36/305 (11%)

Query: 38   KGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLP----------- 86
            K  ++++  Q  A++P    D+L  +L    +  E+L+   G     +            
Sbjct: 1129 KASLKKLRAQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLE 1186

Query: 87   --QDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
              Q  +      Q ELE++  +L+ Y   A  L  W  +  R+Q +   M L +  A+R 
Sbjct: 1187 RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVRE 1246

Query: 145  QELQEQLRVVGEDTKAQLLGGVDEAWAL-------LQGLQSRVVHHTGRFKELFHPYAES 197
            Q  QEQ  +   +   +    V+E           ++  + ++V +  + + +  P  + 
Sbjct: 1247 QLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKP 1303

Query: 198  LVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREEL 257
             V      V + +  +  H        S+ ++ +S  L    +      QQ  ++ RE L
Sbjct: 1304 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE-RERL 1362

Query: 258  SRAFAGTGTEE-------GAGPDPQMLSEEVRQRLQ---AFRQDTYLQIAAFTRAIDQET 307
            +   A    +         A    +  ++E++QR+Q     R++  +      R+I +E 
Sbjct: 1363 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1422

Query: 308  EEVQQ 312
            ++++Q
Sbjct: 1423 QQLRQ 1427



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 65/282 (23%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 38   KGRVEQIHQQKMAR--EPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQ 95
            +   E++  +K+A   E   LK   E  L       E+LR        RL +D    RR+
Sbjct: 1828 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR--------RLAEDEAFQRRR 1879

Query: 96   LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG 155
            L+E+  + KA ++  +A+  +     LE  RQ+       L+E    + ++++E++  + 
Sbjct: 1880 LEEQAAQHKADIEERLAQLRKASDSELE--RQK------GLVEDTLRQRRQVEEEILALK 1931

Query: 156  EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFK---ELFHPYAESLVSGIGRHVQELHRS 212
               +    G  +    L  G        T R K   EL       L +   R  +E    
Sbjct: 1932 ASFEKAAAGKAELELEL--GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1989

Query: 213  VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP 272
            V     A      +    L     LKAK   AR      +LRE           E+ +  
Sbjct: 1990 VQKSLAAEEEAARQRKAALEEVERLKAKVEEAR------RLRER---------AEQESAR 2034

Query: 273  DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQL 314
              Q+  E  ++RLQA       +  A   A+ Q+ +E+QQ L
Sbjct: 2035 QLQLAQEAAQKRLQA-------EEKAHAFAVQQKEQELQQTL 2069


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 42   EQIHQQKMAREPATL--KDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEE 99
            EQ+ Q+  A + + L  KDSL Q    + +   KL  L   E  +  Q     +RQ Q++
Sbjct: 2486 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ-QQQ 2544

Query: 100  LEEVKARLQPYMAEAHELVGWNLEGLR------QQLKPYTMDLMEQVALRVQELQEQLRV 153
            +E+ + RL   M EA        EG+R      QQL+       E +A   Q L+EQL++
Sbjct: 2545 MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL 2604

Query: 154  VGEDTKAQL 162
            + E  +A L
Sbjct: 2605 LEEQHRAAL 2613



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 56/305 (18%), Positives = 119/305 (39%), Gaps = 36/305 (11%)

Query: 38   KGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLP----------- 86
            K  ++++  Q  A++P    D+L  +L    +  E+L+   G     +            
Sbjct: 1133 KASLKKLRAQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLE 1190

Query: 87   --QDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
              Q  +      Q ELE++  +L+ Y   A  L  W  +  R+Q +   M L +  A+R 
Sbjct: 1191 RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVRE 1250

Query: 145  QELQEQLRVVGEDTKAQLLGGVDEAWAL-------LQGLQSRVVHHTGRFKELFHPYAES 197
            Q  QEQ  +   +   +    V+E           ++  + ++V +  + + +  P  + 
Sbjct: 1251 QLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKP 1307

Query: 198  LVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREEL 257
             V      V + +  +  H        S+ ++ +S  L    +      QQ  ++ RE L
Sbjct: 1308 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE-RERL 1366

Query: 258  SRAFAGTGTEE-------GAGPDPQMLSEEVRQRLQ---AFRQDTYLQIAAFTRAIDQET 307
            +   A    +         A    +  ++E++QR+Q     R++  +      R+I +E 
Sbjct: 1367 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1426

Query: 308  EEVQQ 312
            ++++Q
Sbjct: 1427 QQLRQ 1431



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 65/282 (23%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 38   KGRVEQIHQQKMAR--EPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQ 95
            +   E++  +K+A   E   LK   E  L       E+LR        RL +D    RR+
Sbjct: 1832 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR--------RLAEDEAFQRRR 1883

Query: 96   LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG 155
            L+E+  + KA ++  +A+  +     LE  RQ+       L+E    + ++++E++  + 
Sbjct: 1884 LEEQAAQHKADIEERLAQLRKASDSELE--RQK------GLVEDTLRQRRQVEEEILALK 1935

Query: 156  EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFK---ELFHPYAESLVSGIGRHVQELHRS 212
               +    G  +    L  G        T R K   EL       L +   R  +E    
Sbjct: 1936 ASFEKAAAGKAELELEL--GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1993

Query: 213  VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP 272
            V     A      +    L     LKAK   AR      +LRE           E+ +  
Sbjct: 1994 VQKSLAAEEEAARQRKAALEEVERLKAKVEEAR------RLRER---------AEQESAR 2038

Query: 273  DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQL 314
              Q+  E  ++RLQA       +  A   A+ Q+ +E+QQ L
Sbjct: 2039 QLQLAQEAAQKRLQA-------EEKAHAFAVQQKEQELQQTL 2073


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 42   EQIHQQKMAREPATL--KDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEE 99
            EQ+ Q+  A + + L  KDSL Q    + +   KL  L   E  +  Q     +RQ Q++
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ-QQQ 2540

Query: 100  LEEVKARLQPYMAEAHELVGWNLEGLR------QQLKPYTMDLMEQVALRVQELQEQLRV 153
            +E+ + RL   M EA        EG+R      QQL+       E +A   Q L+EQL++
Sbjct: 2541 MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL 2600

Query: 154  VGEDTKAQL 162
            + E  +A L
Sbjct: 2601 LEEQHRAAL 2609



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 56/305 (18%), Positives = 119/305 (39%), Gaps = 36/305 (11%)

Query: 38   KGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLP----------- 86
            K  ++++  Q  A++P    D+L  +L    +  E+L+   G     +            
Sbjct: 1129 KASLKKLRAQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLE 1186

Query: 87   --QDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
              Q  +      Q ELE++  +L+ Y   A  L  W  +  R+Q +   M L +  A+R 
Sbjct: 1187 RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVRE 1246

Query: 145  QELQEQLRVVGEDTKAQLLGGVDEAWAL-------LQGLQSRVVHHTGRFKELFHPYAES 197
            Q  QEQ  +   +   +    V+E           ++  + ++V +  + + +  P  + 
Sbjct: 1247 QLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKP 1303

Query: 198  LVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREEL 257
             V      V + +  +  H        S+ ++ +S  L    +      QQ  ++ RE L
Sbjct: 1304 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE-RERL 1362

Query: 258  SRAFAGTGTEE-------GAGPDPQMLSEEVRQRLQ---AFRQDTYLQIAAFTRAIDQET 307
            +   A    +         A    +  ++E++QR+Q     R++  +      R+I +E 
Sbjct: 1363 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1422

Query: 308  EEVQQ 312
            ++++Q
Sbjct: 1423 QQLRQ 1427



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 65/282 (23%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 38   KGRVEQIHQQKMAR--EPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQ 95
            +   E++  +K+A   E   LK   E  L       E+LR        RL +D    RR+
Sbjct: 1828 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR--------RLAEDEAFQRRR 1879

Query: 96   LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG 155
            L+E+  + KA ++  +A+  +     LE  RQ+       L+E    + ++++E++  + 
Sbjct: 1880 LEEQAAQHKADIEERLAQLRKASDSELE--RQK------GLVEDTLRQRRQVEEEILALK 1931

Query: 156  EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFK---ELFHPYAESLVSGIGRHVQELHRS 212
               +    G  +    L  G        T R K   EL       L +   R  +E    
Sbjct: 1932 ASFEKAAAGKAELELEL--GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1989

Query: 213  VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP 272
            V     A      +    L     LKAK   AR      +LRE           E+ +  
Sbjct: 1990 VQKSLAAEEEAARQRKAALEEVERLKAKVEEAR------RLRER---------AEQESAR 2034

Query: 273  DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQL 314
              Q+  E  ++RLQA       +  A   A+ Q+ +E+QQ L
Sbjct: 2035 QLQLAQEAAQKRLQA-------EEKAHAFAVQQKEQELQQTL 2069


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 42   EQIHQQKMAREPATL--KDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEE 99
            EQ+ Q+  A + + L  KDSL Q    + +   KL  L   E  +  Q     +RQ Q++
Sbjct: 2450 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ-QQQ 2508

Query: 100  LEEVKARLQPYMAEAHELVGWNLEGLR------QQLKPYTMDLMEQVALRVQELQEQLRV 153
            +E+ + RL   M EA        EG+R      QQL+       E +A   Q L+EQL++
Sbjct: 2509 MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL 2568

Query: 154  VGEDTKAQL 162
            + E  +A L
Sbjct: 2569 LEEQHRAAL 2577



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 56/305 (18%), Positives = 119/305 (39%), Gaps = 36/305 (11%)

Query: 38   KGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLP----------- 86
            K  ++++  Q  A++P    D+L  +L    +  E+L+   G     +            
Sbjct: 1097 KASLKKLRAQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLE 1154

Query: 87   --QDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
              Q  +      Q ELE++  +L+ Y   A  L  W  +  R+Q +   M L +  A+R 
Sbjct: 1155 RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVRE 1214

Query: 145  QELQEQLRVVGEDTKAQLLGGVDEAWAL-------LQGLQSRVVHHTGRFKELFHPYAES 197
            Q  QEQ  +   +   +    V+E           ++  + ++V +  + + +  P  + 
Sbjct: 1215 QLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKP 1271

Query: 198  LVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREEL 257
             V      V + +  +  H        S+ ++ +S  L    +      QQ  ++ RE L
Sbjct: 1272 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE-RERL 1330

Query: 258  SRAFAGTGTEE-------GAGPDPQMLSEEVRQRLQ---AFRQDTYLQIAAFTRAIDQET 307
            +   A    +         A    +  ++E++QR+Q     R++  +      R+I +E 
Sbjct: 1331 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1390

Query: 308  EEVQQ 312
            ++++Q
Sbjct: 1391 QQLRQ 1395



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 65/282 (23%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 38   KGRVEQIHQQKMAR--EPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQ 95
            +   E++  +K+A   E   LK   E  L       E+LR        RL +D    RR+
Sbjct: 1796 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR--------RLAEDEAFQRRR 1847

Query: 96   LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG 155
            L+E+  + KA ++  +A+  +     LE  RQ+       L+E    + ++++E++  + 
Sbjct: 1848 LEEQAAQHKADIEERLAQLRKASDSELE--RQK------GLVEDTLRQRRQVEEEILALK 1899

Query: 156  EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFK---ELFHPYAESLVSGIGRHVQELHRS 212
               +    G  +    L  G        T R K   EL       L +   R  +E    
Sbjct: 1900 ASFEKAAAGKAELELEL--GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1957

Query: 213  VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP 272
            V     A      +    L     LKAK   AR      +LRE           E+ +  
Sbjct: 1958 VQKSLAAEEEAARQRKAALEEVERLKAKVEEAR------RLRER---------AEQESAR 2002

Query: 273  DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQL 314
              Q+  E  ++RLQA       +  A   A+ Q+ +E+QQ L
Sbjct: 2003 QLQLAQEAAQKRLQA-------EEKAHAFAVQQKEQELQQTL 2037


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 42   EQIHQQKMAREPATL--KDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEE 99
            EQ+ Q+  A + + L  KDSL Q    + +   KL  L   E  +  Q     +RQ Q++
Sbjct: 2619 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ-QQQ 2677

Query: 100  LEEVKARLQPYMAEAHELVGWNLEGLR------QQLKPYTMDLMEQVALRVQELQEQLRV 153
            +E+ + RL   M EA        EG+R      QQL+       E +A   Q L+EQL++
Sbjct: 2678 MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL 2737

Query: 154  VGEDTKAQL 162
            + E  +A L
Sbjct: 2738 LEEQHRAAL 2746



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 56/305 (18%), Positives = 119/305 (39%), Gaps = 36/305 (11%)

Query: 38   KGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLP----------- 86
            K  ++++  Q  A++P    D+L  +L    +  E+L+   G     +            
Sbjct: 1266 KASLKKLRAQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLE 1323

Query: 87   --QDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
              Q  +      Q ELE++  +L+ Y   A  L  W  +  R+Q +   M L +  A+R 
Sbjct: 1324 RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVRE 1383

Query: 145  QELQEQLRVVGEDTKAQLLGGVDEAWAL-------LQGLQSRVVHHTGRFKELFHPYAES 197
            Q  QEQ  +   +   +    V+E           ++  + ++V +  + + +  P  + 
Sbjct: 1384 QLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKP 1440

Query: 198  LVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREEL 257
             V      V + +  +  H        S+ ++ +S  L    +      QQ  ++ RE L
Sbjct: 1441 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE-RERL 1499

Query: 258  SRAFAGTGTEE-------GAGPDPQMLSEEVRQRLQ---AFRQDTYLQIAAFTRAIDQET 307
            +   A    +         A    +  ++E++QR+Q     R++  +      R+I +E 
Sbjct: 1500 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1559

Query: 308  EEVQQ 312
            ++++Q
Sbjct: 1560 QQLRQ 1564



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 65/282 (23%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 38   KGRVEQIHQQKMAR--EPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQ 95
            +   E++  +K+A   E   LK   E  L       E+LR        RL +D    RR+
Sbjct: 1965 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR--------RLAEDEAFQRRR 2016

Query: 96   LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG 155
            L+E+  + KA ++  +A+  +     LE  RQ+       L+E    + ++++E++  + 
Sbjct: 2017 LEEQAAQHKADIEERLAQLRKASDSELE--RQK------GLVEDTLRQRRQVEEEILALK 2068

Query: 156  EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFK---ELFHPYAESLVSGIGRHVQELHRS 212
               +    G  +    L  G        T R K   EL       L +   R  +E    
Sbjct: 2069 ASFEKAAAGKAELELEL--GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 2126

Query: 213  VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP 272
            V     A      +    L     LKAK   AR      +LRE           E+ +  
Sbjct: 2127 VQKSLAAEEEAARQRKAALEEVERLKAKVEEAR------RLRER---------AEQESAR 2171

Query: 273  DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQL 314
              Q+  E  ++RLQA       +  A   A+ Q+ +E+QQ L
Sbjct: 2172 QLQLAQEAAQKRLQA-------EEKAHAFAVQQKEQELQQTL 2206


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 38.9 bits (89), Expect = 0.007
 Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 9/129 (6%)

Query: 42   EQIHQQKMAREPATL--KDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQLQEE 99
            EQ+ Q+  A + + L  KDSL Q    + +   KL  L   E  +  Q     +RQ Q++
Sbjct: 2460 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQ-QQQ 2518

Query: 100  LEEVKARLQPYMAEAHELVGWNLEGLR------QQLKPYTMDLMEQVALRVQELQEQLRV 153
            +E+ + RL   M EA        EG+R      QQL+       E +A   Q L+EQL++
Sbjct: 2519 MEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQL 2578

Query: 154  VGEDTKAQL 162
            + E  +A L
Sbjct: 2579 LEEQHRAAL 2587



 Score = 33.1 bits (74), Expect = 0.40
 Identities = 56/305 (18%), Positives = 119/305 (39%), Gaps = 36/305 (11%)

Query: 38   KGRVEQIHQQKMAREPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLP----------- 86
            K  ++++  Q  A++P    D+L  +L    +  E+L+   G     +            
Sbjct: 1107 KASLKKLRAQAEAQQPTF--DALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLE 1164

Query: 87   --QDPVGMRRQLQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRV 144
              Q  +      Q ELE++  +L+ Y   A  L  W  +  R+Q +   M L +  A+R 
Sbjct: 1165 RWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVRE 1224

Query: 145  QELQEQLRVVGEDTKAQLLGGVDEAWAL-------LQGLQSRVVHHTGRFKELFHPYAES 197
            Q  QEQ  +   +   +    V+E           ++  + ++V +  + + +  P  + 
Sbjct: 1225 QLRQEQALLEEIERHGE---KVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKP 1281

Query: 198  LVSGIGRHVQELHRSVAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREEL 257
             V      V + +  +  H        S+ ++ +S  L    +      QQ  ++ RE L
Sbjct: 1282 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEE-RERL 1340

Query: 258  SRAFAGTGTEE-------GAGPDPQMLSEEVRQRLQ---AFRQDTYLQIAAFTRAIDQET 307
            +   A    +         A    +  ++E++QR+Q     R++  +      R+I +E 
Sbjct: 1341 AEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEEL 1400

Query: 308  EEVQQ 312
            ++++Q
Sbjct: 1401 QQLRQ 1405



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 65/282 (23%), Positives = 107/282 (37%), Gaps = 45/282 (15%)

Query: 38   KGRVEQIHQQKMAR--EPATLKDSLEQDLNNMNKFLEKLRPLSGSEAPRLPQDPVGMRRQ 95
            +   E++  +K+A   E   LK   E  L       E+LR        RL +D    RR+
Sbjct: 1806 RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLR--------RLAEDEAFQRRR 1857

Query: 96   LQEELEEVKARLQPYMAEAHELVGWNLEGLRQQLKPYTMDLMEQVALRVQELQEQLRVVG 155
            L+E+  + KA ++  +A+  +     LE  RQ+       L+E    + ++++E++  + 
Sbjct: 1858 LEEQAAQHKADIEERLAQLRKASDSELE--RQK------GLVEDTLRQRRQVEEEILALK 1909

Query: 156  EDTKAQLLGGVDEAWALLQGLQSRVVHHTGRFK---ELFHPYAESLVSGIGRHVQELHRS 212
               +    G  +    L  G        T R K   EL       L +   R  +E    
Sbjct: 1910 ASFEKAAAGKAELELEL--GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1967

Query: 213  VAPHAPASPARLSRCVQVLSRKLTLKAKALHARIQQNLDQLREELSRAFAGTGTEEGAGP 272
            V     A      +    L     LKAK   AR      +LRE           E+ +  
Sbjct: 1968 VQKSLAAEEEAARQRKAALEEVERLKAKVEEAR------RLRER---------AEQESAR 2012

Query: 273  DPQMLSEEVRQRLQAFRQDTYLQIAAFTRAIDQETEEVQQQL 314
              Q+  E  ++RLQA       +  A   A+ Q+ +E+QQ L
Sbjct: 2013 QLQLAQEAAQKRLQA-------EEKAHAFAVQQKEQELQQTL 2047


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,374,375
Number of Sequences: 37866
Number of extensions: 656417
Number of successful extensions: 3847
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 182
Number of HSP's that attempted gapping in prelim test: 3560
Number of HSP's gapped (non-prelim): 452
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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