Guide to the Human Genome
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Name: APOE Sequence: fasta or formatted (317aa) NCBI GI: 4557325
Description:

apolipoprotein E precursor

Referenced in:

Epidermal Growth Factor
Lipoproteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            12.3         39           2
 C cysteine            0.6          2           1
 D aspartate           3.5         11           2
 E glutamate          12.6         40           2
 F phenylalanine       1.3          4           1
 G glycine             5.7         18           1
 H histidine           0.6          2           1
 I isoleucine          0.6          2           1
 K lysine              4.1         13           1
 L leucine            12.9         41           2
 M methionine          2.5          8           1
 N asparagine          0.3          1           1
 P proline             2.5          8           1
 Q glutamine          10.1         32           2
 R arginine           10.7         34           1
 S serine              4.4         14           2
 T threonine           3.8         12           1
 V valine              7.6         24           1
 W tryptophan          2.5          8           1
 Y tyrosine            1.3          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   apolipoprotein E precursor 
APOA4                 0.124   apolipoprotein A-IV precursor 
APOA1                 0.058   apolipoprotein A-I preproprotein 
PLEC1                 0.053   plectin 1 isoform 11 
PLEC1                 0.053   plectin 1 isoform 10 
PLEC1                 0.053   plectin 1 isoform 8 
PLEC1                 0.053   plectin 1 isoform 7 
PLEC1                 0.053   plectin 1 isoform 6 
PLEC1                 0.053   plectin 1 isoform 3 
PLEC1                 0.053   plectin 1 isoform 2 
PLEC1                 0.053   plectin 1 isoform 1 
DCTN1                 0.051   dynactin 1 isoform 4 
DCTN1                 0.051   dynactin 1 isoform 3 
DCTN1                 0.051   dynactin 1 isoform 2 
DCTN1                 0.051   dynactin 1 isoform 1 
MYH7B                 0.049   myosin, heavy polypeptide 7B, cardiac muscle, beta ...
CCDC102A              0.049   coiled-coil domain containing 102A 
MYH14                 0.046   myosin, heavy chain 14 isoform 1 
MYH14                 0.046   myosin, heavy chain 14 isoform 2 
MYH14                 0.046   myosin, heavy chain 14 isoform 3 
MYH6                  0.046   myosin heavy chain 6 
APOA5                 0.044   apolipoprotein AV 
ANKRD35               0.044   ankyrin repeat domain 35 
MYH9                  0.042   myosin, heavy polypeptide 9, non-muscle 
FAM184A               0.042   hypothetical protein LOC79632 isoform 2 
FAM184A               0.042   hypothetical protein LOC79632 isoform 1 
SWAP70                0.042   SWAP-70 protein 
MYH15                 0.041   myosin, heavy polypeptide 15 
MYH2                  0.041   myosin, heavy chain 2, skeletal muscle, adult [Homo...
MYH2                  0.041   myosin, heavy chain 2, skeletal muscle, adult [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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