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Search of human proteins with 62988324
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62988324 tenascin N [Homo sapiens]
(1299 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62988324 tenascin N [Homo sapiens] 2681 0.0
gi|157384973 tenascin R [Homo sapiens] 843 0.0
gi|153946395 tenascin C precursor [Homo sapiens] 544 e-154
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 474 e-133
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 384 e-106
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 317 6e-86
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 316 8e-86
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 315 2e-85
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 315 2e-85
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 300 8e-81
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 300 8e-81
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 231 3e-60
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 231 3e-60
gi|8051586 ficolin 2 isoform b precursor [Homo sapiens] 199 1e-50
gi|61744445 ficolin 2 isoform a precursor [Homo sapiens] 199 1e-50
gi|223029463 fibrinogen C domain containing 1 [Homo sapiens] 198 2e-50
gi|223029461 fibrinogen C domain containing 1 [Homo sapiens] 198 2e-50
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 198 2e-50
gi|8051584 ficolin 1 precursor [Homo sapiens] 186 1e-46
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 182 1e-45
gi|23111005 microfibrillar-associated protein 4 [Homo sapiens] 181 5e-45
gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens] 178 3e-44
gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens] 176 1e-43
gi|4757752 angiopoietin-like 1 precursor [Homo sapiens] 171 4e-42
gi|10863949 angiopoietin-like 7 [Homo sapiens] 168 4e-41
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens] 165 2e-40
gi|7705276 angiopoietin 4 [Homo sapiens] 163 1e-39
gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens] 157 5e-38
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop... 156 1e-37
gi|29893555 angiopoietin-like 6 [Homo sapiens] 155 2e-37
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 2681 bits (6949), Expect = 0.0
Identities = 1299/1299 (100%), Positives = 1299/1299 (100%)
Query: 1 MSLQEMFRFPMGLLLGSVLLVASAPATLEPPGCSNKEQQVTVSHTYKIDVPKSALVQVDA 60
MSLQEMFRFPMGLLLGSVLLVASAPATLEPPGCSNKEQQVTVSHTYKIDVPKSALVQVDA
Sbjct: 1 MSLQEMFRFPMGLLLGSVLLVASAPATLEPPGCSNKEQQVTVSHTYKIDVPKSALVQVDA 60
Query: 61 DPQPLSDDGASLLALGEAREEQNIIFRHNIRLQTPQKDCELAGSVQDLLARVKKLEEEMV 120
DPQPLSDDGASLLALGEAREEQNIIFRHNIRLQTPQKDCELAGSVQDLLARVKKLEEEMV
Sbjct: 61 DPQPLSDDGASLLALGEAREEQNIIFRHNIRLQTPQKDCELAGSVQDLLARVKKLEEEMV 120
Query: 121 EMKEQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGR 180
EMKEQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGR
Sbjct: 121 EMKEQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGR 180
Query: 181 CVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGH 240
CVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGH
Sbjct: 181 CVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGH 240
Query: 241 GFCDTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGK 300
GFCDTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGK
Sbjct: 241 GFCDTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGK 300
Query: 301 ELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVT 360
ELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVT
Sbjct: 301 ELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVT 360
Query: 361 DETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYK 420
DETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYK
Sbjct: 361 DETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYK 420
Query: 421 ITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA 480
ITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA
Sbjct: 421 ITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA 480
Query: 481 DGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTD 540
DGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTD
Sbjct: 481 DGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTD 540
Query: 541 RVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHV 600
RVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHV
Sbjct: 541 RVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHV 600
Query: 601 WAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGE 660
WAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGE
Sbjct: 601 WAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGE 660
Query: 661 TREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVT 720
TREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVT
Sbjct: 661 TREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVT 720
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ
Sbjct: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
Query: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE
Sbjct: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
Query: 841 VPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENM 900
VPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENM
Sbjct: 841 VPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENM 900
Query: 901 ATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQ 960
ATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQ
Sbjct: 901 ATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQ 960
Query: 961 ESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLG 1020
ESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLG
Sbjct: 961 ESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLG 1020
Query: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAA 1080
REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAA
Sbjct: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAA 1080
Query: 1081 SGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEF 1140
SGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEF
Sbjct: 1081 SGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEF 1140
Query: 1141 WLGLDKLHNLTTGTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGD 1200
WLGLDKLHNLTTGTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGD
Sbjct: 1141 WLGLDKLHNLTTGTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGD 1200
Query: 1201 ALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPW 1260
ALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPW
Sbjct: 1201 ALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPW 1260
Query: 1261 KGHEFSIPYVELKIRPHGYSREPVLGRKKRTLRGRLRTF 1299
KGHEFSIPYVELKIRPHGYSREPVLGRKKRTLRGRLRTF
Sbjct: 1261 KGHEFSIPYVELKIRPHGYSREPVLGRKKRTLRGRLRTF 1299
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 843 bits (2179), Expect = 0.0
Identities = 480/1322 (36%), Positives = 699/1322 (52%), Gaps = 83/1322 (6%)
Query: 34 SNKEQQVTVSHTYKIDVPKSAL----VQVDADPQPLSDDGASLLALGEARE-EQNIIFRH 88
S+KEQ V +H Y I+VP L ++ A+ + ++D +G+ + E + F H
Sbjct: 57 SSKEQPVVFNHVYNINVPLDNLCSSGLEASAEQEVSAEDETLAEYMGQTSDHESQVTFTH 116
Query: 89 NIRLQTPQKDCELAGS---VQDLLARVKKLEEEMVEMKEQCSAQRCCQ-----GVTDLSR 140
R+ P+K C A S +Q+LL+R++ LE E+ +++QC+A CCQ G D
Sbjct: 117 --RINFPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNAN-CCQESAATGQLDYIP 173
Query: 141 HCSGHGTFSLETCSCHCEEG-------------------------------REGPACERL 169
HCSGHG FS E+C C C EG G C L
Sbjct: 174 HCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSEL 233
Query: 170 ACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCS 229
CP CS G CVDG C+C EPY G DC CP +CSG G C G C C E ++ EDC
Sbjct: 234 RCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCG 293
Query: 230 EKRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVD 289
+++C CSG G C+ G C CEEG+ G DC+ V P+ L++ ++ S+ + W+ V
Sbjct: 294 QRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVT 353
Query: 290 HYLLSYYPLGKELSGKQIQ--VPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLA 347
Y++SY P L G Q+Q VP + I L PG Y +++ V + + S P
Sbjct: 354 EYVISYQPTA--LGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
Query: 348 TTDLAVLGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSR 407
T L+ TE +++V+WE S D +++ + P + VP SD S
Sbjct: 412 ATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVP--SDVTS- 468
Query: 408 YDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQ 467
++ TGL PG EY + VV ++ + P + T ID PT ++ V++ A V W P +
Sbjct: 469 FNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPR 528
Query: 468 AVIDKYVVRY--TSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADT 525
A +D +++Y +G + S + L+PG Y+V V A RG S A T
Sbjct: 529 AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATT 588
Query: 526 NALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSST 585
TEID+P NL T + + WD +A + +Y V Y++ ++ EVLV + T
Sbjct: 589 QFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPT 648
Query: 586 V---LTGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDP 642
LT L PG EY V + A ++S A NA T++DSP++L+ +E ++ W
Sbjct: 649 TRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTK 708
Query: 643 VQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADT 702
ID Y + +T + G EV V K+++S LT L PG EY++ V A++G Q+S ++
Sbjct: 709 ASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTV 768
Query: 703 KAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSA-KDGETREVPVGKEQSS 761
A T +L VT + ++W DR ++ Y+ ++ E EV + +
Sbjct: 769 DAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRH 828
Query: 762 TVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQ 821
VL GL+P EY V++ A G S+ T ID P+++ VT+++ VSW P
Sbjct: 829 AVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPV 888
Query: 822 ATIDRYVVHYTSANGETREVPVGKEQSSTV--------LTGLRPGMEYTVHVWAQKGNQE 873
A+ D Y V Y R VG+ SS V +T L P EY + + + +G +E
Sbjct: 889 ASFDYYRVSY-------RPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREE 941
Query: 874 SKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYT--SADGETREVPV 931
S++ T T +D P +L+ +T A + W ++ Y++ T + GET V
Sbjct: 942 SERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDG 1001
Query: 932 GKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGIL 991
E L L P Y ++A G S T T LDPP NL S VT+ ++
Sbjct: 1002 VSEEFR--LVDLLPSTHYTATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALI 1059
Query: 992 TWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSR 1051
+W PP A+I Y+LTY+ DG+ KE+ + ED L+GL + Y V L A + S
Sbjct: 1060 SWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSS 1119
Query: 1052 NVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIV 1111
ST +T G FPHP DC+Q N + SG+Y I+L+G+ S+ LQVYCDM TDGGGWIV
Sbjct: 1120 ITSTAFTTGGRVFPHPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIV 1179
Query: 1112 FQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQTANESA 1171
FQRR GQ DFF++W Y GFG+ EFWLGLD +H +T + RYE+RVD++ E+A
Sbjct: 1180 FQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDNIHRIT--SQGRYELRVDMRDGQEAA 1237
Query: 1172 YAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGG 1231
+A YD F V S+ YKL +G Y GTAGD+L+YH G F+T DRDND+A++NCA+++ G
Sbjct: 1238 FASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGA 1297
Query: 1232 WWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVELKIRPHGYSREPVLGRKKRT 1291
WWYKNCH N NG+YGE++HS+G+NW WKGHEFSIP+VE+K+RP Y+ + GRK+++
Sbjct: 1298 WWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRP--YNHRLMAGRKRQS 1355
Query: 1292 LR 1293
L+
Sbjct: 1356 LQ 1357
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 544 bits (1401), Expect = e-154
Identities = 332/1039 (31%), Positives = 529/1039 (50%), Gaps = 41/1039 (3%)
Query: 276 DSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNV 334
D+L ++W P +++ + + + + VP S ++ GL T Y +T+R V
Sbjct: 1179 DALKLNWTAPEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGV 1238
Query: 335 KNEVSSSPQHL-LATTDLAVLGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEV 393
+ S++P + + T ++ +G VT+ + ++L + W P D + ++ E
Sbjct: 1239 TQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEE 1298
Query: 394 AE-VTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEG---KPILLNGRTEIDSPT-- 447
A +TVP S +I GL GT Y +T + GE+ G +P+ + TE D P
Sbjct: 1299 AHNLTVPGSL---RSMEIPGLRAGTPYTVT---LHGEVRGHSTRPLAVEVVTE-DLPQLG 1351
Query: 448 NVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG--DTKEMAVHKDESSTVLTGLKPGE 505
++ V D ++W + +V++ + + + + + + GL+
Sbjct: 1352 DLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAAT 1411
Query: 506 AYKVYVWAE-RGNQG---SKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKY 561
Y+V ++ RG + S +A T EI NL +T + +SW + +
Sbjct: 1412 PYRVSIYGVIRGYRTPVLSAEASTAKEPEI---GNLNVSDITPESFNLSWMATDGIFETF 1468
Query: 562 VVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTNAPTD- 619
+ ++ ET E + + + ++GL P ++ V++ +K A T+
Sbjct: 1469 TIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEA 1528
Query: 620 IDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGG--ETREVPVGKEQSSTVLTG 677
+ +NL + TVSW + A D ++V +G + +E + Q L G
Sbjct: 1529 LPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRG 1588
Query: 678 LRPGMEY--MVHVWAQKGDQESKKAD--TKAQTDIDSPQNLVTDRVTENMATVSWDPVRA 733
L G+ Y MV + Q + +A+ T+A+ ++D NL+ T + +SW
Sbjct: 1589 LITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD---NLLVSDATPDGFRLSWTADEG 1645
Query: 734 TIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792
D +V++ K E E+ + + + +TGLR EY + ++ + S+
Sbjct: 1646 VFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAI 1705
Query: 793 AQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE-VPVGKEQSSTV 851
A T + SP+ ++ +TEN+ATVSW A ++ + + Y G T V V ++ T
Sbjct: 1706 ATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTR 1765
Query: 852 LTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQAT 911
L L PG+EY V + A KG +ES+ T +DGP LVT +T++ A W P AT
Sbjct: 1766 LVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIAT 1825
Query: 912 IDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQT 971
+D Y++ YT V LT L P EY + ++A+KG Q+S K T
Sbjct: 1826 VDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT 1885
Query: 972 ELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGL 1031
+LD PR+L + V +LTW PP A + GY+L Y+ DGTVKE+ +G + ++L L
Sbjct: 1886 DLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADL 1945
Query: 1032 EQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGD 1091
Y + A G RS + T +T+G +P P DCSQ N + SGLYTIYL+GD
Sbjct: 1946 SPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGD 2005
Query: 1092 ASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLT 1151
+ L+V+CDM +DGGGWIVF RR G+ +F++ W++Y GFGD +EFWLGLD L+ +T
Sbjct: 2006 KAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKIT 2065
Query: 1152 TGTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFT 1211
+YE+RVDL+ E+A+A+YD F V +K RYKL V Y GTAGD++ YHNG F+
Sbjct: 2066 --AQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFS 2123
Query: 1212 TFDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVE 1271
TFD+D D A++NCAL++ G +WY+NCH N GRYG+ HS+GVNW WKGHE SI + E
Sbjct: 2124 TFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAE 2183
Query: 1272 LKIRPHGYSREPVLGRKKR 1290
+K+RP + + GR+KR
Sbjct: 2184 MKLRPSNFRN--LEGRRKR 2200
Score = 398 bits (1023), Expect = e-110
Identities = 273/955 (28%), Positives = 436/955 (45%), Gaps = 32/955 (3%)
Query: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
E C ++C R CS G C CE+G GP C L+CP C G GRCV+
Sbjct: 494 EDCRDRQC-------PRDCSNRGL--CVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVN 544
Query: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
G+C+CHE ++G DC CP +C G G CV G C CHE F DC + CP DC+ G C
Sbjct: 545 GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604
Query: 244 DTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELS 303
+G C C EG++G DC++V P+ L + + TE+++ ++W+ +V YL+ Y P +
Sbjct: 605 VSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGL 664
Query: 304 GKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDET 363
Q +VP +Q S I L PG +Y + + + S P T L
Sbjct: 665 EMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIK 724
Query: 364 ENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITV 423
E S++VEW+ + +++ + M ++ E+T P++ Y TGL PG EY+I++
Sbjct: 725 ETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEIT-KSLRRPETSYRQTGLAPGQEYEISL 783
Query: 424 VPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD-- 481
++ G + T +D+P+ + VT+ TA ++W A ID + Y D
Sbjct: 784 HIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVP 843
Query: 482 GDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDR 541
GD + + +DE+ + LKP Y+V + + RG+ S A T +D+P NL
Sbjct: 844 GDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVS 903
Query: 542 VTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQ---SSTVLTGLRPGVEYTV 598
T+N+ T+ W +A ID Y ++Y + EV V K Q + T LTGLRPG EY +
Sbjct: 904 QTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGI 963
Query: 599 HVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAG 658
V A K D+ES A NA T++D+PK+L E T+ W A D+Y + Y+
Sbjct: 964 GVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPT 1023
Query: 659 GETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTD-IDSPQNLVTD 717
G+ V + + +S VL GL PG EY V + A+KG +SK A KA T+ +NL
Sbjct: 1024 GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVT 1083
Query: 718 RVTENMATVSWDPVRATIDRYVVRYTSAKDGE-TREVPVGKEQSSTVLTGLRPGVEYTVH 776
V + ++W + ++++ A E R + V + + GL+ YTV
Sbjct: 1084 EVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVS 1143
Query: 777 VWAQKGAQESKKADTKAQT-DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSAN 835
++ + +A T + + +V V + ++W + + + + A+
Sbjct: 1144 IYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEAD 1203
Query: 836 ----GETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT-EIDGPKN 890
+ VP G ST L GL+ YT+ + + + + T E+ N
Sbjct: 1204 TVEAAQNLTVPGGLR--STDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGN 1261
Query: 891 LVTDWVTENMATVSWDPVQATIDKYMVRYTSAD--GETREVPVGKEHSSTVLTGLRPGME 948
L V+ + ++W T D++ ++ AD E + V S + GLR G
Sbjct: 1262 LTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTP 1321
Query: 949 YMVHVWAQKGAQESKKADTKAQTELDPPR--NLRPSAVTQSGGILTWTPPSAQIHGYILT 1006
Y V + + ++ + TE D P+ +L S V G L WT +++
Sbjct: 1322 YTVTLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQ 1380
Query: 1007 YQFPD--GTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLST 1059
Q + + + L + + GLE Y VS+ G R+ +S ST
Sbjct: 1381 VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAST 1435
Score = 179 bits (454), Expect = 2e-44
Identities = 91/236 (38%), Positives = 122/236 (51%), Gaps = 12/236 (5%)
Query: 36 KEQQVTVSHTYKIDVPKSALVQVDADPQPLSDDGASLLALGEAREEQN------IIFRHN 89
+ Q V +H Y I +P + VD + D A E+ +E I+F H
Sbjct: 44 ENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHR 103
Query: 90 IRLQTPQKDCELAGSVQDLLARVKKLEEEMVEMKEQCSAQR-CC----QGVTDLSRHCSG 144
I + C A V++LL+R+++LE + ++EQC+A CC G D CSG
Sbjct: 104 INIPRRACGCAAAPDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSG 163
Query: 145 HGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPE 204
G FS E C C CE G +GP C CPG C GRC+DG+C+C + + G DC ACP
Sbjct: 164 RGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPS 223
Query: 205 NCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCS-GHGFCDTGECYCEEGFTGLDC 259
+C+ G+CV GVC C E + DCS + CP CS HG C G C C +GF G DC
Sbjct: 224 DCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDC 279
Score = 146 bits (368), Expect = 1e-34
Identities = 60/140 (42%), Positives = 80/140 (57%), Gaps = 9/140 (6%)
Query: 126 CSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGR 185
C +C G CSGHG C C+EG G C +L CP C GRCV+G+
Sbjct: 403 CGELKCPNG-------CSGHGR--CVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGK 453
Query: 186 CLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDT 245
C+C + + G DC +CP +C HG CV G+C C + + EDC +++CP DCS G C
Sbjct: 454 CVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVD 513
Query: 246 GECYCEEGFTGLDCAQVVTP 265
G+C CE+GFTG DCA++ P
Sbjct: 514 GQCVCEDGFTGPDCAELSCP 533
Score = 143 bits (361), Expect = 9e-34
Identities = 63/140 (45%), Positives = 75/140 (53%), Gaps = 5/140 (3%)
Query: 131 CCQGVT--DLSRHCSGHGTFSLETCS---CHCEEGREGPACERLACPGACSGHGRCVDGR 185
C +G T D + H + C C C+EG G C CP C GRCVDGR
Sbjct: 332 CEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGR 391
Query: 186 CLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDT 245
C C + + GADCG CP CSGHG CV G C C E + EDCS+ RCP DC G C
Sbjct: 392 CECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVE 451
Query: 246 GECYCEEGFTGLDCAQVVTP 265
G+C CE+GF G DC+ + P
Sbjct: 452 GKCVCEQGFKGYDCSDMSCP 471
Score = 140 bits (353), Expect = 8e-33
Identities = 60/142 (42%), Positives = 77/142 (54%), Gaps = 9/142 (6%)
Query: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
E CS C D R +G +C+CEEG G C + CP AC GRC +
Sbjct: 308 EDCSELICPNDCFDRGRCING---------TCYCEEGFTGEDCGKPTCPHACHTQGRCEE 358
Query: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
G+C+C E + G DC CP +C G CV G C+C + F DC E +CP CSGHG C
Sbjct: 359 GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 418
Query: 244 DTGECYCEEGFTGLDCAQVVTP 265
G+C C+EG+TG DC+Q+ P
Sbjct: 419 VNGQCVCDEGYTGEDCSQLRCP 440
Score = 139 bits (350), Expect = 2e-32
Identities = 59/141 (41%), Positives = 73/141 (51%), Gaps = 9/141 (6%)
Query: 126 CSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGR 185
CS +RC + R G C C++G G C L CP CSGHGRCV+G+
Sbjct: 372 CSEKRCPADCHNRGRCVDGR---------CECDDGFTGADCGELKCPNGCSGHGRCVNGQ 422
Query: 186 CLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDT 245
C+C E Y G DC CP +C G CV G C C + F DCS+ CP DC HG C
Sbjct: 423 CVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVN 482
Query: 246 GECYCEEGFTGLDCAQVVTPQ 266
G C C++G+TG DC P+
Sbjct: 483 GMCVCDDGYTGEDCRDRQCPR 503
Score = 139 bits (349), Expect = 2e-32
Identities = 55/113 (48%), Positives = 63/113 (55%)
Query: 155 CHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVR 214
C C+EG G C L CP C GRC++G C C E + G DCG P CP C G C
Sbjct: 299 CVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEE 358
Query: 215 GVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVTPQG 267
G C C E F DCSEKRCP DC G C G C C++GFTG DC ++ P G
Sbjct: 359 GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNG 411
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 474 bits (1219), Expect = e-133
Identities = 339/1087 (31%), Positives = 513/1087 (47%), Gaps = 83/1087 (7%)
Query: 268 LQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQ--IQVPKEQHSYEILGLLPG 324
L + ++ DSL +SW P + D + + Y K+ G+ ++V E+ + GL PG
Sbjct: 3170 LTVTGSSPDSLSLSWTVPQGRFDSFTVQY----KDRDGQPQVVRVRGEESEVTVGGLEPG 3225
Query: 325 TKYIVTLRNVKNEVSSSPQHLLATT-----DLAV---LGTAWVTDETENSLDVEWENPST 376
KY + L + P + T L V LG V T +S+ + W
Sbjct: 3226 RKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQG 3285
Query: 377 EVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPIL 436
D + ++Y GQ A VP S D ++ ++GL P +YK + ++ P+
Sbjct: 3286 PFDSFLVQYRDAQGQPQA---VPVSGDLRA-VAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341
Query: 437 LNGRTEIDSPTN------VVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVH 490
+ RT D+ + VTD T D+ +SW + D +VV+Y DG + + V
Sbjct: 3342 VEARTAPDTKPSPRLGELTVTD-ATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVA 3400
Query: 491 KDESSTVLTGLKPGEAYKVYVWAERGNQ--GSKKAD-TNALTEIDSPANLVTDRVTENTA 547
++ + GL+P Y+ ++ G + G AD T A E + P +L V E T+
Sbjct: 3401 ANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETS 3460
Query: 548 T---ISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604
+ +SW Q D +VV+Y D Q R V V +Q + + L PG +Y ++
Sbjct: 3461 SSLRLSWTVAQGPFDSFVVQYRDTDGQP-RAVPVAADQRTVTVEDLEPGKKYKFLLYGLL 3519
Query: 605 GDR--------------ESKKADTNAPTDIDSPKN------LVTDRVTENMATVSWDPVQ 644
G + E A AP + P+ VTD ++M +SW Q
Sbjct: 3520 GGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMR-LSWSVAQ 3578
Query: 645 AAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYM-----VHVWAQKGDQESKK 699
D +VV+Y G+ + + V +QS +++GL P Y +H + G ++
Sbjct: 3579 GPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEG 3638
Query: 700 ADTKA---QTDIDSPQNL----VTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGET-- 750
A QT +S L VTD VT + ++W+ D +++R+
Sbjct: 3639 TTGLAPAGQTSEESRPRLSQLSVTD-VTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEP 3697
Query: 751 -------REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQT---DIDSP 800
RE+ V + S VL LR G Y++ ++ +G ++ A+T ++SP
Sbjct: 3698 HPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESP 3757
Query: 801 QNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANG-ETREVPVGKEQSSTVLTGLRPGM 859
++L + E +A V+W P + D + V Y A+G E + V V + + L GL PG
Sbjct: 3758 RDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGA 3817
Query: 860 EYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRY 919
Y V V + +G +ES+ T DGP L +TE A + W P Q +D Y V+
Sbjct: 3818 RYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQV 3877
Query: 920 TSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNL 979
T+ + L L Y V +G + A T L+ PR+L
Sbjct: 3878 TAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDL 3937
Query: 980 RPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPV 1039
VT +LTWT P + GY+L++ P G +E+ L L GL +Y
Sbjct: 3938 EAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNA 3997
Query: 1040 SLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGDASRPLQVY 1099
L A G VST+ +T G R P P DC + QN AS TI+L+G+ RPL V+
Sbjct: 3998 RLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRERPLNVF 4057
Query: 1100 CDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYE 1159
CDMETDGGGW+VFQRR GQ DF++ W Y GFG+ EFWLG + LH+LT Y
Sbjct: 4058 CDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQA--GDYS 4115
Query: 1160 VRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDI 1219
+RVDL+ +E+ +A YD F V S+ E Y+L + Y GTAGD+++YH+G F+ DRD +
Sbjct: 4116 MRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDRDPNS 4175
Query: 1220 ALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVELKIRPHGY 1279
L +CA+++ G WWY+NCH AN NG YG T +GV+W WKG EFS+P+ E+K+RP +
Sbjct: 4176 LLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLRPRNF 4235
Query: 1280 SREPVLG 1286
R P G
Sbjct: 4236 -RSPAGG 4241
Score = 309 bits (791), Expect = 1e-83
Identities = 273/1070 (25%), Positives = 420/1070 (39%), Gaps = 148/1070 (13%)
Query: 122 MKEQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRC 181
+ E CS + C +C G G E C C+ G GP C CP C G GRC
Sbjct: 612 VSEDCSIRTC-------PSNCHGRGR--CEEGRCLCDPGYTGPTCATRMCPADCRGRGRC 662
Query: 182 VDGRCLCHEPYVGADCGYP-----ACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGD 236
V G CLCH Y G DCG ACP C C G C C E F DC+ + CPGD
Sbjct: 663 VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGD 722
Query: 237 CSGHGFCDTGECYCEEGFTGLDCA-QVVTPQGLQLLKNTEDSLLVSWEPS-SQVDHYLLS 294
C G G C G C C++G+ G DC +V T +G+++ E ++ W P+ VD Y +
Sbjct: 723 CRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQ 782
Query: 295 YYPLGKELSGK-QIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAV 353
+ P + S +VP +Y+ GL PG +Y VT+R ++ P TT +
Sbjct: 783 FIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDG 842
Query: 354 LGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGL 413
V T +L++ W P EVD + + Y G + + VP +D +T L
Sbjct: 843 PQDLRVVAVTPTTLELGWLRPQAEVDRFVVSY-VSAGNQRVRLEVPPEADGTL---LTDL 898
Query: 414 HPGTEYKITVVPMRG-----------ELEGKPILLNGRTEIDSPTNV------------- 449
PG EY +TV RG P+ L G T+ P+
Sbjct: 899 MPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQ 958
Query: 450 ---------VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG-DTKEMAVHKDESSTVLT 499
V R V W + +R +G E + D ++
Sbjct: 959 RPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVP 1018
Query: 500 GLKPGEAYKVYVWAERGN---------QGSKKADTNALTEIDSPANL----VTDRVTENT 546
PG Y++ + QG D + P L VTDR T ++
Sbjct: 1019 PPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDR-TSDS 1077
Query: 547 ATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGD 606
+ W + D +V++Y D Q + V V Q S V+T L PG +Y ++ G
Sbjct: 1078 LLLRWTVPEGEFDSFVIQYKDRDGQ-PQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGK 1136
Query: 607 R-------ESKKADTNAPTDIDSPK--NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSA 657
+ E+K + P+ P NL T + +SW + D ++V+Y
Sbjct: 1137 KRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDR 1196
Query: 658 GGETREVPVGKEQSSTVLTGLRPGMEYMVHVW------------AQKGDQESKKADTKAQ 705
G + VPV + S V++ L P +Y ++ A +K +
Sbjct: 1197 DGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRP 1256
Query: 706 TDIDSP--QNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTV 763
++ P L VT + +SW + D ++V+Y A+ G+ + VPV +++
Sbjct: 1257 EFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQ-GQPQAVPVAGDENEVT 1315
Query: 764 LTGLRPGVEYTVHVWAQKGAQ----ESKKADTKAQTDID---SPQNLVTD--------WV 808
+ GL P +Y ++++ +G Q ES A T Q D+D SP L T+ +
Sbjct: 1316 VPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLL 1375
Query: 809 TENTATVS--------WDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGME 860
E T T S W Q + D + V Y +G R V VG ++S + GL PG +
Sbjct: 1376 GELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHK 1435
Query: 861 YTVHVW----AQKGNQESKKADTKAQTEIDGPKN-----------LVTDWVTENMATVSW 905
Y +H++ Q+ S T Q E P VTD VT N +SW
Sbjct: 1436 YKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTD-VTPNSVGLSW 1494
Query: 906 DPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKA 965
+ D ++V+Y DG+ + VPV + + L P +Y ++++ Q
Sbjct: 1495 TVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPL 1554
Query: 966 DTKAQTELDPPR---------------NLRPSAVTQSGGILTWTPPSAQIHGYILTYQFP 1010
T PP L + +T L+WT P + +++ Y+
Sbjct: 1555 SVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR 1614
Query: 1011 DGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
DG + + + + + + LE Y L + G+R VS TV
Sbjct: 1615 DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTV 1664
Score = 228 bits (580), Expect = 4e-59
Identities = 206/955 (21%), Positives = 384/955 (40%), Gaps = 149/955 (15%)
Query: 268 LQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQ--IQVPKEQHSYEILGLLPG 324
L + ++ DSL +SW P + D + + Y K+ G+ ++V ++ + GL PG
Sbjct: 2528 LTVTGSSPDSLSLSWTVPQGRFDSFTVQY----KDRDGRPQAVRVGGQESKVTVRGLEPG 2583
Query: 325 TKYIVTLRNVKNEVSSSPQHLLATTDLAV------------------LGTAWVTDETENS 366
KY + L + P + T+ LG +TD T +S
Sbjct: 2584 RKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDS 2643
Query: 367 LDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPM 426
L + W P + D++ ++Y GQ A V VP D + I+GL P +YK+ +
Sbjct: 2644 LSLSWTVPEGQFDHFLVQYRNGDGQPKA-VRVPGHEDGVT---ISGLEPDHKYKMNLYGF 2699
Query: 427 RGELEGKPILLNGRTEIDSPTNVVTDRVTE--------------------DTATVSWDPV 466
G PI + G T + T T+ TE D+ ++SW
Sbjct: 2700 HGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIP 2759
Query: 467 QAVIDKYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTN 526
Q D + V+Y DG + M V +ES + GL+PG YK++++ + T
Sbjct: 2760 QGHFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
Query: 527 ALTEIDS------------PAN------LVTDRVTENTATISWDPVQATIDKYVVRYTSA 568
+TE ++ P N L T ++ ++SW + D ++V+Y +
Sbjct: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG 2879
Query: 569 DDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRE----------SKKADTNAPT 618
D Q + V V + ++GL P +Y ++++ G + + + +T APT
Sbjct: 2880 DGQ-PKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
Query: 619 D--IDSPK--------NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGK 668
+ ++P+ L + + ++SW Q D + V+Y G + V V
Sbjct: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
Query: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQE------------SKKADTKAQTDIDSPQNLVT 716
E+S + GL PG +Y +H++ Q +A+T +P+ +
Sbjct: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
Query: 717 DRV--------TENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLR 768
R+ T + ++SW D ++V+Y + DG+ + V V + ++GL
Sbjct: 3059 PRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLE 3117
Query: 769 PGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQ------------------NLVTDWVTE 810
P +Y ++++ G Q T+ ++P L +
Sbjct: 3118 PDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSP 3177
Query: 811 NTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKG 870
++ ++SW Q D + V Y +G+ + V V E+S + GL PG +Y +H++ G
Sbjct: 3178 DSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLY---G 3234
Query: 871 NQESKKADTKAQTEIDGP-----------KNLVTDWVTENMATVSWDPVQATIDKYMVRY 919
E ++ + I P L VT + +SW Q D ++V+Y
Sbjct: 3235 LHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQY 3294
Query: 920 TSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNL 979
A G+ + VPV + + ++GL P +Y ++ + + +A+T D +
Sbjct: 3295 RDAQGQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSP 3354
Query: 980 RPSAVTQSGGI-----LTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQG 1034
R +T + L+WT P + +++ Y+ DG ++ + + + +QGLE
Sbjct: 3355 RLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPS 3414
Query: 1035 ATYPVSLVAFKGGRRSRNVSTTLSTVGARF---PHPSDCSQVQQNSNAASGLYTI 1086
Y L G +R +S +T PH + + ++ S++ +T+
Sbjct: 3415 RKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTV 3469
Score = 226 bits (576), Expect = 1e-58
Identities = 220/914 (24%), Positives = 370/914 (40%), Gaps = 134/914 (14%)
Query: 268 LQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKE--QHSYEILGLLPG 324
L + T DSLL+ W P + D +++ Y K+ G+ VP E Q S I L PG
Sbjct: 1068 LTVTDRTSDSLLLRWTVPEGEFDSFVIQY----KDRDGQPQVVPVEGPQRSAVITSLDPG 1123
Query: 325 TKYIVTLRNVKNEVSSSP----QHLLATTDLAV-----LGTAWVTDETENSLDVEWENPS 375
KY L + P +L +D + LG WVTD T +SL + W P
Sbjct: 1124 RKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPE 1183
Query: 376 TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKP 434
+ D + ++Y G+ +V V P+ S + ++ L P +Y+ T+ + + P
Sbjct: 1184 GQFDTFMVQYRDRDGRPQVVPVEGPERS-----FVVSSLDPDHKYRFTLFGIANKKRYGP 1238
Query: 435 ILLNGRTE------------IDSPT--NVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA 480
+ +G T ++ P + VT D+ +SW Q D ++V+Y A
Sbjct: 1239 LTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDA 1298
Query: 481 DGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQG-------SKKADTNALTEIDS 533
G + + V DE+ + GL P YK+ ++ RG Q +K A + E S
Sbjct: 1299 QGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPS 1358
Query: 534 PANLVTDR----------------VTENTATISWDPVQATIDKYVVRYTSADDQETREVL 577
P L T+ + ++ ++ W Q + D + V+Y D + R V
Sbjct: 1359 PTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGR-PRAVR 1417
Query: 578 VGKEQSSTVLTGLRPGVEYTVHVWA-QKGDR--------------ESKKADTNAPTDIDS 622
VG ++S + GL PG +Y +H++ +G R E T +P +
Sbjct: 1418 VGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRL 1477
Query: 623 PKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGM 682
+ VTD VT N +SW + D ++V+Y G+ + VPV +Q + L P
Sbjct: 1478 GELTVTD-VTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPER 1536
Query: 683 EYMVHVWAQKGDQE---------SKKADTKAQTDIDSPQ------NLVTDRVTENMATVS 727
+Y ++++ Q + T+ P L +T + +S
Sbjct: 1537 KYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLS 1596
Query: 728 WDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWA-QKGAQES 786
W D +VV+Y +DG+ + VPV +Q + L P +Y ++ Q G + S
Sbjct: 1597 WTVPEGEFDSFVVQYKD-RDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRS 1655
Query: 787 K---KADTKAQTDID--SPQNLVTDWVTENT---ATVSWDPVQATIDRYVVHYTSANGET 838
+A T A+ D +P L WVT+ T +SW + D +VV + +G
Sbjct: 1656 PVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDG-P 1714
Query: 839 REVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDG------P 888
+ VPV + S +T L G +Y ++ G + + T+A++ +D P
Sbjct: 1715 QVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPP 1774
Query: 889 K-----NLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGL 943
K L VT+N +SW + D ++V+Y DG+ + VPV + GL
Sbjct: 1775 KPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGL 1834
Query: 944 RPGMEYMVHVW--------------AQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGG 989
P Y + ++ A +E + +T A T P +L V ++
Sbjct: 1835 DPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATS 1894
Query: 990 ---ILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKG 1046
L+W + + + Y DG ++ +++G + L GLE Y V+L F
Sbjct: 1895 HTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSD 1954
Query: 1047 GRRSRNVSTTLSTV 1060
G+ V TV
Sbjct: 1955 GKHVGPVHVEALTV 1968
Score = 225 bits (574), Expect = 2e-58
Identities = 217/959 (22%), Positives = 370/959 (38%), Gaps = 141/959 (14%)
Query: 274 TEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGTKYIVTLR 332
T DSL +SW P Q DH+L+ Y + K ++VP + I GL P KY + L
Sbjct: 2854 TPDSLSLSWMVPEGQFDHFLVQYR--NGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLY 2911
Query: 333 NVKNEVSSSPQHLLATT--------------------DLAVLGTAWVTDETENSLDVEWE 372
P ++ T + +LG VT + +SL + W
Sbjct: 2912 GFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWT 2971
Query: 373 NPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEG 432
P D + ++Y G+ V + +S + GL PG +YK+ + +
Sbjct: 2972 IPQGRFDSFTVQYKDRDGRP----QVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRV 3027
Query: 433 KPILLNGRT----EIDSPTNV-----------------VTDRVTEDTATVSWDPVQAVID 471
P+ G T E ++ V VTD T D+ ++SW + D
Sbjct: 3028 GPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD-ATPDSLSLSWMVPEGQFD 3086
Query: 472 KYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEI 531
++V+Y + DG K + V E ++GL+P YK+ ++ G Q +TE
Sbjct: 3087 HFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEE 3146
Query: 532 DSPA------------------NLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQET 573
++P+ L + ++ ++SW Q D + V+Y D Q
Sbjct: 3147 ETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQ-P 3205
Query: 574 REVLVGKEQSSTVLTGLRPGVEYTVHVWA-QKGDRESKKADTNAPTDIDSP-------KN 625
+ V V E+S + GL PG +Y +H++ +G R + + +P
Sbjct: 3206 QVVRVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGE 3265
Query: 626 LVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYM 685
L VT + +SW Q D ++V+Y A G+ + VPV + + ++GL P +Y
Sbjct: 3266 LAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVPVSGDLRAVAVSGLDPARKYK 3325
Query: 686 VHVWAQKGDQESKKADTKAQTDID---SPQ--NLVTDRVTENMATVSWDPVRATIDRYVV 740
++ + + +A+T D SP+ L T + +SW D +VV
Sbjct: 3326 FLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVV 3385
Query: 741 RYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE---SKKADTKAQTDI 797
+Y KDG + VPV Q + GL P +Y ++ G + T A +
Sbjct: 3386 QYKD-KDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEK 3444
Query: 798 DSPQNLVTDWVTENTAT---VSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTG 854
+ P +L V E T++ +SW Q D +VV Y +G+ R VPV +Q + +
Sbjct: 3445 ELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVED 3504
Query: 855 LRPGMEYTVHVWAQKGN--------------QESKKADTKAQTEIDGPKN------LVTD 894
L PG +Y ++ G +E A A + P+ VTD
Sbjct: 3505 LEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTD 3564
Query: 895 WVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVW 954
++M +SW Q D ++V+Y +G+ + + V + S +++GL P Y ++
Sbjct: 3565 TTPDSM-RLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLY 3623
Query: 955 AQKGAQESKKADTKAQTELDP---------PR--NLRPSAVTQSGGILTWTPPSAQIHGY 1003
+ + T L P PR L + VT S L W P +
Sbjct: 3624 GLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSF 3683
Query: 1004 ILTYQFPDGTV----------KEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNV 1053
+L + P + +E+ + L+ L G Y ++L +G ++ ++
Sbjct: 3684 LLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSI 3743
Query: 1054 STTLSTVGARFPHPSDC--SQVQQNS---------NAASGLYTIYLHGDASRPLQVYCD 1101
T T+ P D S++++ S + A Y D P V D
Sbjct: 3744 QGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVD 3802
Score = 215 bits (547), Expect = 3e-55
Identities = 207/961 (21%), Positives = 380/961 (39%), Gaps = 172/961 (17%)
Query: 268 LQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL--GLLPG 324
LQ+ T++S+ +SW P Q D +++ Y K+ G+ VP E E+ GL P
Sbjct: 1782 LQVTTVTQNSVGLSWTVPEGQFDSFVVQY----KDRDGQPQVVPVEGSLREVSVPGLDPA 1837
Query: 325 TKYIVTLRNVKNEVSSSPQHLLATT-----------------DLAVLGTAWVTDETENSL 367
+Y + L + + P +A T LG V + T ++L
Sbjct: 1838 HRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTL 1897
Query: 368 DVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMR 427
+ W E D ++++Y GQ + + + ++ ++GL Y +T+
Sbjct: 1898 HLSWMVTEGEFDSFEIQYTDRDGQ----LQMVRIGGDRNDITLSGLESDHRYLVTLYGFS 1953
Query: 428 GELEGKPILLNGRT--EIDSPTN-----------------VVTDRVTEDTATVSWDPVQA 468
P+ + T E + P+ VTD T D+ ++SW +
Sbjct: 1954 DGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTD-ATPDSLSLSWTVPEG 2012
Query: 469 VIDKYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQG----SKKAD 524
D ++V+Y + DG K + V E ++GL+P YK+ ++ G Q S
Sbjct: 2013 QFDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGV 2072
Query: 525 TNALTEIDSP----------------ANLVTDRVTENTATISWDPVQATIDKYVVRYTSA 568
T A E SP L + ++ ++SW Q D + V+Y
Sbjct: 2073 TAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDR 2132
Query: 569 DDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVT 628
D + + V VG E+S + GL PG +Y +H++ G E ++ + + +P+
Sbjct: 2133 DGR-PQVVRVGGEESEVTVGGLEPGRKYKMHLY---GLHEGRRVGPVSAVGVTAPEEESP 2188
Query: 629 DR--------------VTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTV 674
D +T + ++SW + D ++V++ + G+ + V V +
Sbjct: 2189 DAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVT 2248
Query: 675 LTGLRPGMEYMVHVWAQKG-----------------DQESKKADTKAQTDIDSP-----Q 712
++GL P +Y ++++ G D+E A T+ T + P +
Sbjct: 2249 ISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTP-EPPIKPRLE 2307
Query: 713 NLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVE 772
L T + ++SW D ++V+Y + DG+ + V + ++GL P +
Sbjct: 2308 ELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNK 2366
Query: 773 YTVHVWAQKGAQE----SKKADTKAQTDIDSPQ----------------NLVTDWVTENT 812
Y ++++ G Q S T A+ + SP L + ++
Sbjct: 2367 YKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDS 2426
Query: 813 ATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVW------ 866
++SW Q D + V Y +G + V VG E+S + GL PG +Y +H++
Sbjct: 2427 LSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGR 2486
Query: 867 -----------AQKGNQESKKADTKAQTEIDGPK------NLVTDWVTENMATVSWDPVQ 909
A + + + + T+ TE GP L + + ++SW Q
Sbjct: 2487 RVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQ 2546
Query: 910 ATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVW-----------AQKG 958
D + V+Y DG + V VG + S + GL PG +Y +H++ + G
Sbjct: 2547 GRFDSFTVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVG 2606
Query: 959 AQESKKADTKAQTELDPPRNLRP-------SAVTQSGGILTWTPPSAQIHGYILTYQFPD 1011
E + T+A + P ++P + T L+WT P Q +++ Y+ D
Sbjct: 2607 VTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGD 2666
Query: 1012 GTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTT-LSTVGARFPHPSDC 1070
G K +++ + + GLE Y ++L F GG+R +S ++ P P++
Sbjct: 2667 GQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTEL 2726
Query: 1071 S 1071
S
Sbjct: 2727 S 2727
Score = 212 bits (539), Expect = 2e-54
Identities = 199/843 (23%), Positives = 338/843 (40%), Gaps = 130/843 (15%)
Query: 354 LGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITG 412
LG VTD T +SL + W P E D + ++Y GQ +V V P+ S IT
Sbjct: 1065 LGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQVVPVEGPQRSAV-----ITS 1119
Query: 413 LHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPT---------NVVTDRVTEDTATVSW 463
L PG +YK + G+ P++ + S N+ T D+ +SW
Sbjct: 1120 LDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSW 1179
Query: 464 DPVQAVIDKYVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVW--AERGNQGSK 521
+ D ++V+Y DG + + V E S V++ L P Y+ ++ A + G
Sbjct: 1180 TVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPL 1239
Query: 522 KADTNALTE----------IDSP--ANLVTDRVTENTATISWDPVQATIDKYVVRYTSAD 569
AD E ++ P L VT ++ +SW Q D ++V+Y A
Sbjct: 1240 TADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQ 1299
Query: 570 DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDR----ESKKADTNAPTDID---S 622
Q + G E TV GL P +Y ++++ +G + ES A T D+D S
Sbjct: 1300 GQPQAVPVAGDENEVTV-PGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPS 1358
Query: 623 PKNLVTDR----------------VTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPV 666
P L T+ + + ++ W Q + D + V+Y G R V V
Sbjct: 1359 PTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGRPRAVRV 1418
Query: 667 GKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQ-------------- 712
G ++S + GL PG +Y +H++ G E ++ + + +PQ
Sbjct: 1419 GGKESEVTVGGLEPGHKYKMHLY---GLHEGQRVGPVSAVGVTAPQQEETPPATESPLEP 1475
Query: 713 ---NLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRP 769
L VT N +SW D ++V+Y KDG+ + VPV +Q + L P
Sbjct: 1476 RLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD-KDGQPQVVPVAADQREVTVYNLEP 1534
Query: 770 GVEYTVHVWAQKGAQE---------SKKADTKAQTDIDSP-------QNLVTDWVTENTA 813
+Y ++++ Q + T+ P + VTD +T ++
Sbjct: 1535 ERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTD-ITPDSV 1593
Query: 814 TVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQE 873
+SW + D +VV Y +G+ + VPV +Q + L P +Y ++ + +
Sbjct: 1594 GLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKR 1653
Query: 874 SKKADTKAQTEIDG------PKNLVTDWVTE---NMATVSWDPVQATIDKYMVRYTSADG 924
+A+T G P L WVT+ + +SW + D ++V++ DG
Sbjct: 1654 RSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDG 1713
Query: 925 ETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQE----SKKADTKAQTELD------ 974
+ VPV S +T L G +Y ++ G + + T+A++ +D
Sbjct: 1714 -PQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKR 1772
Query: 975 PPR-----NLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQ 1029
PP+ L+ + VTQ+ L+WT P Q +++ Y+ DG + + + + ++
Sbjct: 1773 PPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVP 1832
Query: 1030 GLEQGATY--------------PVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQ 1075
GL+ Y P+S VA GR TT T A PH + + +
Sbjct: 1833 GLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEA 1892
Query: 1076 NSN 1078
S+
Sbjct: 1893 TSH 1895
Score = 168 bits (426), Expect = 3e-41
Identities = 86/218 (39%), Positives = 109/218 (50%), Gaps = 33/218 (15%)
Query: 81 EQNIIFRHNIRLQTPQKDCE---------LAGSVQDLLARVKKLEEEMVEMKEQCSAQRC 131
E+ ++F H I L P C LA VQ L R++ LEE + +KEQC+ C
Sbjct: 68 EKQVVFTHRINLP-PSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGG-C 125
Query: 132 CQ-------GVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERL--------------- 169
C G TD+ CS HG F L C+C CE G GP C
Sbjct: 126 CPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASG 185
Query: 170 ACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCS 229
+CP C+ GRCV GRC+C Y G CG+P+CP +C G G CV+GVC C F DCS
Sbjct: 186 SCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCS 245
Query: 230 EKRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVTPQG 267
++ CP CS G C+ G C C+ G+TG DC P+G
Sbjct: 246 QRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRG 283
Score = 146 bits (368), Expect = 1e-34
Identities = 63/142 (44%), Positives = 80/142 (56%), Gaps = 9/142 (6%)
Query: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
E C ++RC C GHG E C C+ G G C +CPG C G G+C+D
Sbjct: 521 EDCGSRRC-------PGDCRGHGL--CEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571
Query: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
GRC+C + Y G DCG CP +CS HG C GVC C E ++SEDCS + CP +C G G C
Sbjct: 572 GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631
Query: 244 DTGECYCEEGFTGLDCAQVVTP 265
+ G C C+ G+TG CA + P
Sbjct: 632 EEGRCLCDPGYTGPTCATRMCP 653
Score = 143 bits (361), Expect = 9e-34
Identities = 61/128 (47%), Positives = 71/128 (55%), Gaps = 2/128 (1%)
Query: 140 RHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGY 199
R C G G E C C G G C +CPG C G GRC GRC+C Y G DCG
Sbjct: 437 RDCRGRGR--CENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494
Query: 200 PACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDC 259
ACP +C G G CV G C C+ F EDC +RCPGDC GHG C+ G C C+ G++G DC
Sbjct: 495 RACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDC 554
Query: 260 AQVVTPQG 267
+ P G
Sbjct: 555 STRSCPGG 562
Score = 142 bits (358), Expect = 2e-33
Identities = 64/150 (42%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
Query: 134 GVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYV 193
GV C G G E+ C C G G C ACPG C G GRCVDGRC+C+ +
Sbjct: 462 GVRSCPGDCRGRGR--CESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFT 519
Query: 194 GADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEG 253
G DCG CP +C GHG C GVC C + EDCS + CPG C G G C G C CE+G
Sbjct: 520 GEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDG 579
Query: 254 FTGLDCAQVVTPQGLQLLKNTEDSLLVSWE 283
++G DC P +D + + WE
Sbjct: 580 YSGEDCGVRQCPNDCSQHGVCQDGVCICWE 609
Score = 141 bits (356), Expect = 4e-33
Identities = 62/142 (43%), Positives = 74/142 (52%), Gaps = 9/142 (6%)
Query: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
E CS + C R C G G E C C+ G G C +CPG C+ GRC D
Sbjct: 366 EDCSTRTC-------PRDCRGRGR--CEDGECICDTGYSGDDCGVRSCPGDCNQRGRCED 416
Query: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
GRC+C Y G DCG ACP +C G G C GVC C+ + EDC + CPGDC G G C
Sbjct: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476
Query: 244 DTGECYCEEGFTGLDCAQVVTP 265
++G C C G+TG DC P
Sbjct: 477 ESGRCMCWPGYTGRDCGTRACP 498
Score = 130 bits (328), Expect = 6e-30
Identities = 61/149 (40%), Positives = 72/149 (48%), Gaps = 2/149 (1%)
Query: 134 GVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYV 193
G+ R CS G E C C G G C +CP CS GRC DGRC+C Y
Sbjct: 276 GMRSCPRGCSQRGR--CENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYT 333
Query: 194 GADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEG 253
G DCG +CP +C G CV G C C + EDCS + CP DC G G C+ GEC C+ G
Sbjct: 334 GEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTG 393
Query: 254 FTGLDCAQVVTPQGLQLLKNTEDSLLVSW 282
++G DC P ED V W
Sbjct: 394 YSGDDCGVRSCPGDCNQRGRCEDGRCVCW 422
Score = 125 bits (314), Expect = 3e-28
Identities = 54/143 (37%), Positives = 68/143 (47%), Gaps = 9/143 (6%)
Query: 124 EQCSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVD 183
E C + C +G + R G C C+ G G C +CP C GRCVD
Sbjct: 304 EDCGVRSCPRGCSQRGRCKDGR---------CVCDPGYTGEDCGTRSCPWDCGEGGRCVD 354
Query: 184 GRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFC 243
GRC+C Y G DC CP +C G G C G C C + +DC + CPGDC+ G C
Sbjct: 355 GRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRC 414
Query: 244 DTGECYCEEGFTGLDCAQVVTPQ 266
+ G C C G+TG DC P+
Sbjct: 415 EDGRCVCWPGYTGTDCGSRACPR 437
Score = 122 bits (307), Expect = 2e-27
Identities = 48/106 (45%), Positives = 58/106 (54%)
Query: 155 CHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVR 214
C C G G C CPG C GHG C DG C+C Y G DC +CP C G G+C+
Sbjct: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571
Query: 215 GVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDCA 260
G C C + + EDC ++CP DCS HG C G C C EG+ DC+
Sbjct: 572 GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCS 617
Score = 122 bits (305), Expect = 3e-27
Identities = 51/118 (43%), Positives = 60/118 (50%), Gaps = 2/118 (1%)
Query: 142 CSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGRCLCHEPYVGADCGYPA 201
C G G C C G GP C + +CP CS GRC GRC+C Y G DCG +
Sbjct: 222 CQGRGRCVQGVCVCRA--GFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRS 279
Query: 202 CPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDTGECYCEEGFTGLDC 259
CP CS G C G C C+ + EDC + CP CS G C G C C+ G+TG DC
Sbjct: 280 CPRGCSQRGRCENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDC 337
Score = 121 bits (304), Expect = 4e-27
Identities = 57/151 (37%), Positives = 72/151 (47%), Gaps = 9/151 (5%)
Query: 126 CSAQRCCQGVTDLSRHCSGHGTFSLETCSCHCEEGREGPACERLACPGACSGHGRCVDGR 185
CS + C +G + R C G C C+ G G C +CP CS GRC +GR
Sbjct: 244 CSQRSCPRGCSQRGR-CEGG--------RCVCDPGYTGDDCGMRSCPRGCSQRGRCENGR 294
Query: 186 CLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCSEKRCPGDCSGHGFCDT 245
C+C+ Y G DCG +CP CS G C G C C + EDC + CP DC G C
Sbjct: 295 CVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVD 354
Query: 246 GECYCEEGFTGLDCAQVVTPQGLQLLKNTED 276
G C C G+TG DC+ P+ + ED
Sbjct: 355 GRCVCWPGYTGEDCSTRTCPRDCRGRGRCED 385
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 384 bits (985), Expect = e-106
Identities = 234/674 (34%), Positives = 341/674 (50%), Gaps = 29/674 (4%)
Query: 638 VSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYM-----VHVWAQK 692
+SW Q D +VV+Y G+ + + V +QS +++GL P Y +H +
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
Query: 693 GDQESKKADTKA---QTDIDSPQNL----VTDRVTENMATVSWDPVRATIDRYVVRYTSA 745
G ++ A QT +S L VTD VT + ++W+ D +++R+
Sbjct: 63 GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTD-VTTSSLRLNWEAPPGAFDSFLLRFGVP 121
Query: 746 KDGET---------REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQT- 795
RE+ V + S VL LR G Y++ ++ +G ++ A+T
Sbjct: 122 SPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTL 181
Query: 796 --DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANG-ETREVPVGKEQSSTVL 852
++SP++L + E +A V+W P + D + V Y A+G E + V V + + L
Sbjct: 182 SPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKL 241
Query: 853 TGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATI 912
GL PG Y V V + +G +ES+ T DGP L +TE A + W P Q +
Sbjct: 242 QGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPV 301
Query: 913 DKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTE 972
D Y V+ T+ + L L Y V +G + A T
Sbjct: 302 DTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTG 361
Query: 973 LDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLE 1032
L+ PR+L VT +LTWT P + GY+L++ P G +E+ L L GL
Sbjct: 362 LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLF 421
Query: 1033 QGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGDA 1092
+Y L A G VST+ +T G R P P DC + QN AS TI+L+G+
Sbjct: 422 PSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNR 481
Query: 1093 SRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTT 1152
RPL V+CDMETDGGGW+VFQRR GQ DF++ W Y GFG+ EFWLG + LH+LT
Sbjct: 482 ERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQ 541
Query: 1153 GTPARYEVRVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTT 1212
Y +RVDL+ +E+ +A YD F V S+ E Y+L + Y GTAGD+++YH+G F+
Sbjct: 542 A--GDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSA 599
Query: 1213 FDRDNDIALSNCALTHHGGWWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVEL 1272
DRD + L +CA+++ G WWY+NCH AN NG YG T +GV+W WKG EFS+P+ E+
Sbjct: 600 RDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEM 659
Query: 1273 KIRPHGYSREPVLG 1286
K+RP + R P G
Sbjct: 660 KLRPRNF-RSPAGG 672
Score = 115 bits (289), Expect = 2e-25
Identities = 107/406 (26%), Positives = 165/406 (40%), Gaps = 22/406 (5%)
Query: 309 VPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAW---------- 358
V +Q I GL P T Y L + P TT LA G
Sbjct: 31 VDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQL 90
Query: 359 -VTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVP----KSSDPKSRYD--IT 411
VTD T +SL + WE P D + LR+G + + P + P +R+ +
Sbjct: 91 SVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLR 150
Query: 412 GLHPGTEYKITVVPMRGELEGKPILLNGRT---EIDSPTNVVTDRVTEDTATVSWDPVQA 468
L GT Y +T+ +RG + I RT ++SP ++ + E +A V+W P +
Sbjct: 151 DLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPS 210
Query: 469 VIDKYVVRYTSAD-GDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNA 527
D + V Y AD G+ + + V + L GL PG Y+V V + RG + S+
Sbjct: 211 RADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFL 270
Query: 528 LTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVL 587
T D P L +TE A + W P Q +D Y V+ T+ + G L
Sbjct: 271 TTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYP-L 329
Query: 588 TGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAI 647
L YT V +G + A T +++P++L VT A ++W
Sbjct: 330 HDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRP 389
Query: 648 DKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKG 693
Y++ + + GG+ +E+ + +S L GL P Y + A G
Sbjct: 390 AGYLLSFHTPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWG 435
Score = 112 bits (281), Expect = 2e-24
Identities = 102/439 (23%), Positives = 169/439 (38%), Gaps = 31/439 (7%)
Query: 369 VEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRG 428
+ W D + ++Y GQ A + +S+ I+GL P T Y+ + +
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQPQALLV----DGDQSKILISGLEPSTPYRFLLYGLHE 58
Query: 429 ELEGKPILLNGRTEIDSPTNV------------VTDRVTEDTATVSWDPVQAVIDKYVVR 476
P+ G T + VTD VT + ++W+ D +++R
Sbjct: 59 GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTD-VTTSSLRLNWEAPPGAFDSFLLR 117
Query: 477 YTSADGDT----------KEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTN 526
+ T +E+ V S VL L+ G Y + ++ RG +
Sbjct: 118 FGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGT 177
Query: 527 ALT---EIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQS 583
A T ++SP +L + E +A ++W P + D + V Y AD E + V V +
Sbjct: 178 ARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQAR 237
Query: 584 STVLTGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPV 643
+ L GL PG Y V V + +G ES+ T D P L +TE A + W P
Sbjct: 238 TQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPP 297
Query: 644 QAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTK 703
Q +D Y V+ T+ G + L L Y V +G + A
Sbjct: 298 QNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASIT 357
Query: 704 AQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTV 763
T +++P++L VT A ++W Y++ + G+ +E+ + +S
Sbjct: 358 FTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSF-HTPGGQNQEILLPGGITSHQ 416
Query: 764 LTGLRPGVEYTVHVWAQKG 782
L GL P Y + A G
Sbjct: 417 LLGLFPSTSYNARLQAMWG 435
Score = 100 bits (249), Expect = 9e-21
Identities = 99/373 (26%), Positives = 153/373 (41%), Gaps = 24/373 (6%)
Query: 252 EGFTGLDCAQVVTPQG------LQLLKNTEDSLLVSWE-PSSQVDHYLLSY--------Y 296
EG TGL A + + L + T SL ++WE P D +LL +
Sbjct: 68 EGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLE 127
Query: 297 PLGKELSGKQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGT 356
P + L +++ VP +HS + L GT Y +TL ++ + A T VL +
Sbjct: 128 PHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLES 187
Query: 357 ---AWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSR-YDITG 412
++ E S V W P + D +K+ Y G E V V D ++R + G
Sbjct: 188 PRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQV----DGQARTQKLQG 243
Query: 413 LHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDK 472
L PG Y++TVV +RG E +P+ T D PT + +TE A + W P Q +D
Sbjct: 244 LIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDT 303
Query: 473 YVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEID 532
Y V+ T+ + L L Y V RG + A T ++
Sbjct: 304 YDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLE 363
Query: 533 SPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRP 592
+P +L VT TA ++W Y++ + + Q +E+L+ +S L GL P
Sbjct: 364 APRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQ-NQEILLPGGITSHQLLGLFP 422
Query: 593 GVEYTVHVWAQKG 605
Y + A G
Sbjct: 423 STSYNARLQAMWG 435
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 317 bits (811), Expect = 6e-86
Identities = 235/815 (28%), Positives = 378/815 (46%), Gaps = 26/815 (3%)
Query: 268 LQLLKNTEDSLLVSWEP--SSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGT 325
L + T+ S+ + W P SS + Y ++ G+ + + V Y + GL PG
Sbjct: 1273 LSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGI 1332
Query: 326 KYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVDYYKLR 384
Y +++ + N S+P L T + T+ +++ V W P S ++ + +R
Sbjct: 1333 DYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1392
Query: 385 YGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI 443
Y P+ +E VAE+++ S + +T L PGTEY ++V + + E P+ +T +
Sbjct: 1393 YSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1449
Query: 444 DSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESSTVLTGL 501
DSPT + +T ++ TV W +A I Y +R+ G +E V +S LT L
Sbjct: 1450 DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1509
Query: 502 KPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKY 561
PG Y V + A G + S T D P +L T + ISWD T+ Y
Sbjct: 1510 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYY 1569
Query: 562 VVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KKADTNA 616
+ Y + + +E V +S+ ++GL+PGV+YT+ V+A G +S K N
Sbjct: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
Query: 617 PTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKEQSSTV 674
T+ID P + V +N +V W P + + Y V T + G T+ G +Q+
Sbjct: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
Query: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRAT 734
+ GL+P +EY+V V+AQ ES+ A T+ID P+ L V + ++W+ +
Sbjct: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1749
Query: 735 IDRYVVRYTSAKDG--ETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792
+ RY V Y+S +DG E P G+E ++ L GLRPG EYTV V A ES+
Sbjct: 1750 VSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
Query: 793 AQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGETREVPVGKEQSST 850
T I +P +L VT + + W P + Y V T G +E+ + + SS
Sbjct: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
Query: 851 VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDWVTENMATVSWDPV 908
V++GL +Y V V+A K S+ A T + P+ TE T+SW
Sbjct: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
Query: 909 QATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADT 967
TI + V A+G+T + + + S +TGL+PG +Y ++++ S
Sbjct: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
Query: 968 KAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGRED--QR 1025
A T +D P NLR A T + +++W PP A+I GYI+ Y+ P +E+
Sbjct: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
Query: 1026 FALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
+ GLE G Y + ++A K ++S + TV
Sbjct: 2049 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 2083
Score = 313 bits (801), Expect = 9e-85
Identities = 222/747 (29%), Positives = 346/747 (46%), Gaps = 25/747 (3%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 1358 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1417
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 1418 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1477
Query: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 1478 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533
Query: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 1534 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
Query: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
Query: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1713
Query: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREV---PVG 667
A T+ID PK L V + ++W+ Q + +Y V Y+S E+ P G
Sbjct: 1714 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1773
Query: 668 KEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVS 727
+E ++ L GLRPG EY V V A D ES+ T I +P +L +VT +
Sbjct: 1774 EEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
Query: 728 WDPVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
W P + Y VR T K G +E+ + + SS V++GL +Y V V+A K S
Sbjct: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
Query: 787 KKADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPV 843
+ A T ++ P+ TE T T+SW TI + V ANG+T + +
Sbjct: 1893 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1952
Query: 844 GKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATV 903
+ S +TGL+PG +Y ++++ N S A T ID P NL T N V
Sbjct: 1953 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 2012
Query: 904 SWDPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQE 961
SW P +A I Y+++Y REV T +TGL PG EY ++V A K Q+
Sbjct: 2013 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
Query: 962 SKKADTKAQTELDPPRNLRPSAVTQSG 988
S+ + +T P P T +G
Sbjct: 2073 SEPLIGRKKTVQKTPFVTHPGYDTGNG 2099
Score = 270 bits (689), Expect = 9e-72
Identities = 197/637 (30%), Positives = 295/637 (46%), Gaps = 25/637 (3%)
Query: 255 TGLDCAQVVTPQGLQLLKNTEDSLLVSW-EPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
TGLD +P G+ T +S V W P + + Y + ++P ++ +VP +
Sbjct: 1447 TGLD-----SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1501
Query: 314 HSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN 373
+S + L PGT+Y+V++ + S +T V V T SL + W+
Sbjct: 1502 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
Query: 374 PSTEVDYYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGE--- 429
P+ V YY++ YG G V E TVP S KS I+GL PG +Y ITV + G
Sbjct: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTGRGDS 1618
Query: 430 -LEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT--SADGDTKE 486
KPI +N RTEID P+ + V +++ +V W P + + Y V T + G TK
Sbjct: 1619 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1678
Query: 487 MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENT 546
D++ + GL+P Y V V+A+ + S+ A+T ID P L V ++
Sbjct: 1679 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS 1738
Query: 547 ATISWDPVQATIDKYVVRYTSADD--QETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604
I+W+ Q + +Y V Y+S +D E G+E ++ L GLRPG EYTV V A
Sbjct: 1739 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALH 1797
Query: 605 GDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETR 662
D ES+ T I +P +L +VT + W P + Y VR T G +
Sbjct: 1798 DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857
Query: 663 EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVT 720
E+ + + SS V++GL +Y V V+A K S+ A T ++ P+ T
Sbjct: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1917
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
E T+SW TI + V A + + + S +TGL+PG +Y ++++
Sbjct: 1918 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1977
Query: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
S A T ID+P NL T N+ VSW P +A I Y++ Y RE
Sbjct: 1978 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037
Query: 841 VPVGKEQSST--VLTGLRPGMEYTVHVWAQKGNQESK 875
V T +TGL PG EYT++V A K NQ+S+
Sbjct: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 2074
Score = 261 bits (667), Expect = 3e-69
Identities = 221/826 (26%), Positives = 366/826 (44%), Gaps = 39/826 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
Query: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
Query: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Query: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGETREVPVGKE- 669
++ +L +T++ + W P+ ++ I Y + +AG +P+ ++
Sbjct: 1259 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAG---EGIPIFEDF 1315
Query: 670 -QSST---VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMAT 725
SS +TGL PG++Y + V ES QT + P +L + +
Sbjct: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMR 1375
Query: 726 VSW-DPVRATIDRYVVRYTSAKDGE-TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGA 783
V+W P + ++VRY+ K+ E E+ + ++ VLT L PG EY V V +
Sbjct: 1376 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1435
Query: 784 QESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV--HYTSANGETREV 841
ES + +T +DSP + +T N+ TV W +ATI Y + H +G RE
Sbjct: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1495
Query: 842 PVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMA 901
V ++S LT L PG EY V + A G +ES + T D P++L T
Sbjct: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
Query: 902 TVSWDPVQATIDKYMVRY--TSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
+SWD T+ Y + Y T + +E V S+ ++GL+PG++Y + V+A G
Sbjct: 1556 LISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGR 1615
Query: 960 QE----SKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGT 1013
+ SK +TE+D P ++ + V + + W P S+ + GY +T + G
Sbjct: 1616 GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1675
Query: 1014 VKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLST 1059
K G + ++GL+ Y VS+ A S+ + T T
Sbjct: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
Score = 225 bits (574), Expect = 2e-58
Identities = 227/841 (26%), Positives = 360/841 (42%), Gaps = 61/841 (7%)
Query: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
Query: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
Query: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
Query: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
Query: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
Query: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
Query: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
Query: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
+QSS L PG+EY V V+ K ++ES E+ +L +T++ + W
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW 1287
Query: 906 DPV-QATIDKYMVRYTSADGETREVPVGKEHSST-----VLTGLRPGMEYMVHVWAQKGA 959
P+ +TI Y + +A GE +P+ ++ + +TGL PG++Y + V
Sbjct: 1288 TPLNSSTIIGYRITVVAA-GE--GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
Query: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKE 1016
ES QT + PP +LR + + +TW PPS + +++ Y + V E
Sbjct: 1345 GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1404
Query: 1017 MQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQN 1076
+ + D L L G Y VS+ + S + T G P D S + N
Sbjct: 1405 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1463
Query: 1077 S 1077
S
Sbjct: 1464 S 1464
Score = 220 bits (560), Expect = 8e-57
Identities = 210/756 (27%), Positives = 330/756 (43%), Gaps = 57/756 (7%)
Query: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
Query: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Query: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
Query: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
Query: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
Query: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
Query: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
Query: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
Query: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
Query: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
Query: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
T +G+ + E V + SS L PG+EY V V+ K +ES E+
Sbjct: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQL 1270
Query: 977 RNLRPSAVTQSGGILTWTP-PSAQIHGYILTYQFPDGTVK--EMQLGREDQRFALQGLEQ 1033
+L +T S L WTP S+ I GY +T + E + + + GLE
Sbjct: 1271 TDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
Query: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSD 1069
G Y +S++ G S + T T P P+D
Sbjct: 1331 GIDYDISVITLINGGESAPTTLTQQTA---VPPPTD 1363
Score = 192 bits (487), Expect = 2e-48
Identities = 168/669 (25%), Positives = 281/669 (42%), Gaps = 60/669 (8%)
Query: 261 QVVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
++ P +Q+ ++S+ V W PSS V Y ++ P K +Q I
Sbjct: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
GL P +Y+V++ S P A T++ TD +S+ + WE+P +V
Sbjct: 1692 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
Query: 380 YYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNG 439
Y++ Y + ++ P + ++ GL PG+EY ++VV + ++E +P++
Sbjct: 1752 RYRVTYS--SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
Query: 440 RTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD--GDTKEMAVHKDESSTV 497
T I +PT++ +VT + + W P + Y VR T + G KE+ + D SS V
Sbjct: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
Query: 498 LTGLKPGEAYKVYVWAERGNQGSKKAD--TNALTEIDSPANLVTDRVTENTATISWDPVQ 555
++GL Y+V V+A + S+ A L + P TE T TISW
Sbjct: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
Query: 556 ATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
TI + V A+ Q + + + S +TGL+PG +Y ++++ + S +
Sbjct: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSST-- 673
A T ID+P NL T N VSW P +A I Y+++Y G REV T
Sbjct: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
Query: 674 VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRA 733
+TGL PG EY ++V A K +Q+S+ + +T +P
Sbjct: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP---------------------- 2087
Query: 734 TIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKA 793
V + G ++P +G +P V + ++ + G + + T
Sbjct: 2088 -----FVTHPGYDTGNGIQLP--------GTSGQQPSVGQQM-IFEEHGFRRTTPPTTAT 2133
Query: 794 ---QTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV--HYTSANGETREVPVGKEQS 848
P N+ + +++ T+SW P Q T Y++ H + E + V +
Sbjct: 2134 PIRHRPRPYPPNVGQEALSQ--TTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTST 2190
Query: 849 STVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPV 908
S LTGL G Y + V A K Q K + E+ N V + + + +DP
Sbjct: 2191 SATLTGLTRGATYNIIVEALKDQQRH-----KVREEVVTVGNSVNEGLNQPTDDSCFDPY 2245
Query: 909 QATIDKYMV 917
T+ Y V
Sbjct: 2246 --TVSHYAV 2252
Score = 37.0 bits (84), Expect = 0.12
Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 14/127 (11%)
Query: 534 PANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPG 593
P N+ + +++ T ISW P Q T + + + D+E + V +S LTGL G
Sbjct: 2143 PPNVGQEALSQTT--ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2200
Query: 594 VEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVR 653
Y + V A K D++ K T V + V E + + D + D Y V
Sbjct: 2201 ATYNIIVEALK-DQQRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVS 2248
Query: 654 YTSAGGE 660
+ + G E
Sbjct: 2249 HYAVGDE 2255
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 316 bits (810), Expect = 8e-86
Identities = 233/805 (28%), Positives = 375/805 (46%), Gaps = 26/805 (3%)
Query: 268 LQLLKNTEDSLLVSWEP--SSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGT 325
L + T+ S+ + W P SS + Y ++ G+ + + V Y + GL PG
Sbjct: 1273 LSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGI 1332
Query: 326 KYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVDYYKLR 384
Y +++ + N S+P L T + T+ +++ V W P S ++ + +R
Sbjct: 1333 DYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1392
Query: 385 YGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI 443
Y P+ +E VAE+++ S + +T L PGTEY ++V + + E P+ +T +
Sbjct: 1393 YSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1449
Query: 444 DSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESSTVLTGL 501
DSPT + +T ++ TV W +A I Y +R+ G +E V +S LT L
Sbjct: 1450 DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1509
Query: 502 KPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKY 561
PG Y V + A G + S T D P +L T + ISWD T+ Y
Sbjct: 1510 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYY 1569
Query: 562 VVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KKADTNA 616
+ Y + + +E V +S+ ++GL+PGV+YT+ V+A G +S K N
Sbjct: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
Query: 617 PTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKEQSSTV 674
T+ID P + V +N +V W P + + Y V T + G T+ G +Q+
Sbjct: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
Query: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRAT 734
+ GL+P +EY+V V+AQ ES+ A T+ID P+ L V + ++W+ +
Sbjct: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1749
Query: 735 IDRYVVRYTSAKDG--ETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792
+ RY V Y+S +DG E P G+E ++ L GLRPG EYTV V A ES+
Sbjct: 1750 VSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
Query: 793 AQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGETREVPVGKEQSST 850
T I +P +L VT + + W P + Y V T G +E+ + + SS
Sbjct: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
Query: 851 VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDWVTENMATVSWDPV 908
V++GL +Y V V+A K S+ A T + P+ TE T+SW
Sbjct: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
Query: 909 QATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADT 967
TI + V A+G+T + + + S +TGL+PG +Y ++++ S
Sbjct: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
Query: 968 KAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGRED--QR 1025
A T +D P NLR A T + +++W PP A+I GYI+ Y+ P +E+
Sbjct: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
Query: 1026 FALQGLEQGATYPVSLVAFKGGRRS 1050
+ GLE G Y + ++A K ++S
Sbjct: 2049 ATITGLEPGTEYTIYVIALKNNQKS 2073
Score = 313 bits (801), Expect = 9e-85
Identities = 226/760 (29%), Positives = 348/760 (45%), Gaps = 31/760 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 1358 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1417
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 1418 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1477
Query: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 1478 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533
Query: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 1534 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
Query: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
Query: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1713
Query: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREV---PVG 667
A T+ID PK L V + ++W+ Q + +Y V Y+S E+ P G
Sbjct: 1714 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1773
Query: 668 KEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVS 727
+E ++ L GLRPG EY V V A D ES+ T I +P +L +VT +
Sbjct: 1774 EEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
Query: 728 WDPVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
W P + Y VR T K G +E+ + + SS V++GL +Y V V+A K S
Sbjct: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
Query: 787 KKADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPV 843
+ A T ++ P+ TE T T+SW TI + V ANG+T + +
Sbjct: 1893 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1952
Query: 844 GKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATV 903
+ S +TGL+PG +Y ++++ N S A T ID P NL T N V
Sbjct: 1953 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 2012
Query: 904 SWDPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQE 961
SW P +A I Y+++Y REV T +TGL PG EY ++V A K Q+
Sbjct: 2013 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
Query: 962 S------KKADTKAQTELDPPRNLRPSAVTQSGGILTWTP 995
S KK D Q P NL + + TP
Sbjct: 2073 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTP 2112
Score = 270 bits (691), Expect = 5e-72
Identities = 198/646 (30%), Positives = 299/646 (46%), Gaps = 25/646 (3%)
Query: 255 TGLDCAQVVTPQGLQLLKNTEDSLLVSW-EPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
TGLD +P G+ T +S V W P + + Y + ++P ++ +VP +
Sbjct: 1447 TGLD-----SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1501
Query: 314 HSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN 373
+S + L PGT+Y+V++ + S +T V V T SL + W+
Sbjct: 1502 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
Query: 374 PSTEVDYYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGE--- 429
P+ V YY++ YG G V E TVP S KS I+GL PG +Y ITV + G
Sbjct: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTGRGDS 1618
Query: 430 -LEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT--SADGDTKE 486
KPI +N RTEID P+ + V +++ +V W P + + Y V T + G TK
Sbjct: 1619 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1678
Query: 487 MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENT 546
D++ + GL+P Y V V+A+ + S+ A+T ID P L V ++
Sbjct: 1679 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS 1738
Query: 547 ATISWDPVQATIDKYVVRYTSADD--QETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604
I+W+ Q + +Y V Y+S +D E G+E ++ L GLRPG EYTV V A
Sbjct: 1739 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALH 1797
Query: 605 GDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETR 662
D ES+ T I +P +L +VT + W P + Y VR T G +
Sbjct: 1798 DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857
Query: 663 EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVT 720
E+ + + SS V++GL +Y V V+A K S+ A T ++ P+ T
Sbjct: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1917
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
E T+SW TI + V A + + + S +TGL+PG +Y ++++
Sbjct: 1918 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1977
Query: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
S A T ID+P NL T N+ VSW P +A I Y++ Y RE
Sbjct: 1978 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037
Query: 841 VPVGKEQSST--VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE 884
V T +TGL PG EYT++V A K NQ+S+ + +T+
Sbjct: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 2083
Score = 261 bits (667), Expect = 3e-69
Identities = 221/826 (26%), Positives = 366/826 (44%), Gaps = 39/826 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
Query: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
Query: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Query: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGETREVPVGKE- 669
++ +L +T++ + W P+ ++ I Y + +AG +P+ ++
Sbjct: 1259 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAG---EGIPIFEDF 1315
Query: 670 -QSST---VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMAT 725
SS +TGL PG++Y + V ES QT + P +L + +
Sbjct: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMR 1375
Query: 726 VSW-DPVRATIDRYVVRYTSAKDGE-TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGA 783
V+W P + ++VRY+ K+ E E+ + ++ VLT L PG EY V V +
Sbjct: 1376 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1435
Query: 784 QESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV--HYTSANGETREV 841
ES + +T +DSP + +T N+ TV W +ATI Y + H +G RE
Sbjct: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1495
Query: 842 PVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMA 901
V ++S LT L PG EY V + A G +ES + T D P++L T
Sbjct: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
Query: 902 TVSWDPVQATIDKYMVRY--TSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
+SWD T+ Y + Y T + +E V S+ ++GL+PG++Y + V+A G
Sbjct: 1556 LISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGR 1615
Query: 960 QE----SKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGT 1013
+ SK +TE+D P ++ + V + + W P S+ + GY +T + G
Sbjct: 1616 GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1675
Query: 1014 VKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLST 1059
K G + ++GL+ Y VS+ A S+ + T T
Sbjct: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
Score = 225 bits (574), Expect = 2e-58
Identities = 227/841 (26%), Positives = 360/841 (42%), Gaps = 61/841 (7%)
Query: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
Query: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
Query: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
Query: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
Query: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
Query: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
Query: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
Query: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
+QSS L PG+EY V V+ K ++ES E+ +L +T++ + W
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW 1287
Query: 906 DPV-QATIDKYMVRYTSADGETREVPVGKEHSST-----VLTGLRPGMEYMVHVWAQKGA 959
P+ +TI Y + +A GE +P+ ++ + +TGL PG++Y + V
Sbjct: 1288 TPLNSSTIIGYRITVVAA-GE--GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
Query: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKE 1016
ES QT + PP +LR + + +TW PPS + +++ Y + V E
Sbjct: 1345 GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1404
Query: 1017 MQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQN 1076
+ + D L L G Y VS+ + S + T G P D S + N
Sbjct: 1405 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1463
Query: 1077 S 1077
S
Sbjct: 1464 S 1464
Score = 220 bits (560), Expect = 8e-57
Identities = 210/756 (27%), Positives = 330/756 (43%), Gaps = 57/756 (7%)
Query: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
Query: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Query: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
Query: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
Query: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
Query: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
Query: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
Query: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
Query: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
Query: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
Query: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
T +G+ + E V + SS L PG+EY V V+ K +ES E+
Sbjct: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQL 1270
Query: 977 RNLRPSAVTQSGGILTWTP-PSAQIHGYILTYQFPDGTVK--EMQLGREDQRFALQGLEQ 1033
+L +T S L WTP S+ I GY +T + E + + + GLE
Sbjct: 1271 TDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
Query: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSD 1069
G Y +S++ G S + T T P P+D
Sbjct: 1331 GIDYDISVITLINGGESAPTTLTQQTA---VPPPTD 1363
Score = 196 bits (499), Expect = 9e-50
Identities = 180/689 (26%), Positives = 289/689 (41%), Gaps = 44/689 (6%)
Query: 261 QVVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
++ P +Q+ ++S+ V W PSS V Y ++ P K +Q I
Sbjct: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
GL P +Y+V++ S P A T++ TD +S+ + WE+P +V
Sbjct: 1692 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
Query: 380 YYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNG 439
Y++ Y + ++ P + ++ GL PG+EY ++VV + ++E +P++
Sbjct: 1752 RYRVTYS--SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
Query: 440 RTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD--GDTKEMAVHKDESSTV 497
T I +PT++ +VT + + W P + Y VR T + G KE+ + D SS V
Sbjct: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
Query: 498 LTGLKPGEAYKVYVWAERGNQGSKKAD--TNALTEIDSPANLVTDRVTENTATISWDPVQ 555
++GL Y+V V+A + S+ A L + P TE T TISW
Sbjct: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
Query: 556 ATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
TI + V A+ Q + + + S +TGL+PG +Y ++++ + S +
Sbjct: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSST-- 673
A T ID+P NL T N VSW P +A I Y+++Y G REV T
Sbjct: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
Query: 674 VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQ-------NLVTDRVTENMATV 726
+TGL PG EY ++V A K +Q+S+ + +TD + PQ NL + + +TV
Sbjct: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD-ELPQLVTLPHPNLHGPEILDVPSTV 2108
Query: 727 SWDPVRATIDRYVVRYTSAKDGETREVP-VGKEQ-----------SSTVLTGLRPGVE-Y 773
P T Y G + + P VG++ T T +R Y
Sbjct: 2109 QKTPF-VTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPY 2167
Query: 774 TVHVWAQKGAQESKKADTKAQTDIDSP---QNLVTDWVTENTATVSWDPVQATIDRYVV- 829
+V + + D P N T + T+SW P Q T Y++
Sbjct: 2168 PPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT-SEYIIS 2226
Query: 830 -HYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGP 888
H + E + V +S LTGL G Y + V A K Q K + E+
Sbjct: 2227 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH-----KVREEVVTV 2281
Query: 889 KNLVTDWVTENMATVSWDPVQATIDKYMV 917
N V + + + +DP T+ Y V
Sbjct: 2282 GNSVNEGLNQPTDDSCFDPY--TVSHYAV 2308
Score = 79.3 bits (194), Expect = 2e-14
Identities = 100/425 (23%), Positives = 161/425 (37%), Gaps = 44/425 (10%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEILG 320
V P+ ++ TE ++ +SW ++ + + + P + + Q + + SY I G
Sbjct: 1905 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITG 1963
Query: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDY 380
L PGT Y + L + + SSP + A+T + T NSL V W+ P +
Sbjct: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 2023
Query: 381 YKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPIL---- 436
Y ++Y G EV VP+ + ITGL PGTEY I V+ ++ + +P++
Sbjct: 2024 YIIKY-EKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 2081
Query: 437 --------------LNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG 482
L+G +D P+ V + T +D + + G
Sbjct: 2082 TDELPQLVTLPHPNLHGPEILDVPSTV---QKTPFVTHPGYDTGNGIQLPGTSGQQPSVG 2138
Query: 483 DTKEMAVHKDESSTVLTGLKP----GEAYKVYVWAERGNQGSKKADTNALTEIDSPA--- 535
H +T T P Y V E + D + P
Sbjct: 2139 QQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNP 2198
Query: 536 NLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVE 595
N T + + TISW P Q T + + + D+E + V +S LTGL G
Sbjct: 2199 NASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 2258
Query: 596 YTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT 655
Y + V A K D++ K T V + V E + + D + D Y V +
Sbjct: 2259 YNIIVEALK-DQQRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVSHY 2306
Query: 656 SAGGE 660
+ G E
Sbjct: 2307 AVGDE 2311
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 315 bits (807), Expect = 2e-85
Identities = 240/820 (29%), Positives = 382/820 (46%), Gaps = 28/820 (3%)
Query: 265 PQGLQLLKNTEDSLL-VSWEPSSQVD--HYLLSYYPL-GKELSGKQIQVPKEQHSYEILG 320
P L L N + +L VSWE S+ D Y ++ P G++ + + V +Q S
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
Query: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVD 379
L PG +Y V++ VK++ S P + T+ +++ V W P S ++
Sbjct: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
Query: 380 YYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
+ +RY P+ +E VAE+++ S + +T L PGTEY ++V + + E P+
Sbjct: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
Query: 439 GRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESST 496
+T +DSPT + +T ++ TV W +A I Y +R+ G +E V +S
Sbjct: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
LT L PG Y V + A G + S T D P +L T + ISWD
Sbjct: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV 1473
Query: 557 TIDKYVVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KK 611
T+ Y + Y + + +E V +S+ ++GL+PGV+YT+ V+A G +S K
Sbjct: 1474 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKE 669
N T+ID P + V +N +V W P + + Y V T + G T+ G +
Sbjct: 1534 ISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
Query: 670 QSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWD 729
Q+ + GL+P +EY+V V+AQ ES+ A T+ID P+ L V + ++W+
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
Query: 730 PVRATIDRYVVRYTSAKDG--ETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
+ + RY V Y+S +DG E P G+E ++ L GLRPG EYTV V A ES+
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALHDDMESQ 1712
Query: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGETREVPVGK 845
T I +P +L VT + + W P + Y V T G +E+ +
Sbjct: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDWVTENMATV 903
+ SS V++GL +Y V V+A K S+ A T + P+ TE T+
Sbjct: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1832
Query: 904 SWDPVQATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
SW TI + V A+G+T + + + S +TGL+PG +Y ++++ S
Sbjct: 1833 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1892
Query: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGRE 1022
A T +D P NLR A T + +++W PP A+I GYI+ Y+ P +E+
Sbjct: 1893 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1952
Query: 1023 D--QRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
+ GLE G Y + ++A K ++S + TV
Sbjct: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992
Score = 313 bits (801), Expect = 9e-85
Identities = 222/747 (29%), Positives = 346/747 (46%), Gaps = 25/747 (3%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1386
Query: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 1387 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1442
Query: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 1443 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1502
Query: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 1503 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1562
Query: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
Query: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREV---PVG 667
A T+ID PK L V + ++W+ Q + +Y V Y+S E+ P G
Sbjct: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1682
Query: 668 KEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVS 727
+E ++ L GLRPG EY V V A D ES+ T I +P +L +VT +
Sbjct: 1683 EEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
Query: 728 WDPVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
W P + Y VR T K G +E+ + + SS V++GL +Y V V+A K S
Sbjct: 1742 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
Query: 787 KKADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPV 843
+ A T ++ P+ TE T T+SW TI + V ANG+T + +
Sbjct: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1861
Query: 844 GKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATV 903
+ S +TGL+PG +Y ++++ N S A T ID P NL T N V
Sbjct: 1862 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1921
Query: 904 SWDPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQE 961
SW P +A I Y+++Y REV T +TGL PG EY ++V A K Q+
Sbjct: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
Query: 962 SKKADTKAQTELDPPRNLRPSAVTQSG 988
S+ + +T P P T +G
Sbjct: 1982 SEPLIGRKKTVQKTPFVTHPGYDTGNG 2008
Score = 304 bits (778), Expect = 4e-82
Identities = 240/848 (28%), Positives = 381/848 (44%), Gaps = 35/848 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
Query: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
Query: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Query: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGE--TREVPVGK 668
+ P +L + + V+W P + + ++VRY+ E E+ +
Sbjct: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
Query: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSW 728
++ VLT L PG EY+V V + ES + +T +DSP + +T N TV W
Sbjct: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
Query: 729 DPVRATIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
RATI Y +R+ G RE V ++S LT L PG EY V + A G +ES
Sbjct: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1438
Query: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGK 845
+ T D P++L T + +SWD T+ Y + Y T N +E V
Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDGPKNLVTDWVTENMA 901
+S+ ++GL+PG++YT+ V+A G + SK +TEID P + V +N
Sbjct: 1499 SKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI 1558
Query: 902 TVSWDPVQATIDKYMVRYT--SADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
+V W P + + Y V T + G T+ G + + + GL+P +EY+V V+AQ +
Sbjct: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
Query: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEM-- 1017
ES+ A T +D P+ L + V + W P Q+ Y +TY P+ + E+
Sbjct: 1619 GESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
Query: 1018 QLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
E+ LQGL G+ Y VS+VA S+ + T ST P P+D Q
Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA---IPAPTDLKFTQVTP 1735
Query: 1078 NAASGLYT 1085
+ S +T
Sbjct: 1736 TSLSAQWT 1743
Score = 270 bits (689), Expect = 9e-72
Identities = 197/637 (30%), Positives = 295/637 (46%), Gaps = 25/637 (3%)
Query: 255 TGLDCAQVVTPQGLQLLKNTEDSLLVSW-EPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
TGLD +P G+ T +S V W P + + Y + ++P ++ +VP +
Sbjct: 1356 TGLD-----SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
Query: 314 HSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN 373
+S + L PGT+Y+V++ + S +T V V T SL + W+
Sbjct: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
Query: 374 PSTEVDYYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGE--- 429
P+ V YY++ YG G V E TVP S KS I+GL PG +Y ITV + G
Sbjct: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTGRGDS 1527
Query: 430 -LEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT--SADGDTKE 486
KPI +N RTEID P+ + V +++ +V W P + + Y V T + G TK
Sbjct: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1587
Query: 487 MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENT 546
D++ + GL+P Y V V+A+ + S+ A+T ID P L V ++
Sbjct: 1588 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS 1647
Query: 547 ATISWDPVQATIDKYVVRYTSADD--QETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604
I+W+ Q + +Y V Y+S +D E G+E ++ L GLRPG EYTV V A
Sbjct: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALH 1706
Query: 605 GDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETR 662
D ES+ T I +P +L +VT + W P + Y VR T G +
Sbjct: 1707 DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766
Query: 663 EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVT 720
E+ + + SS V++GL +Y V V+A K S+ A T ++ P+ T
Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
E T+SW TI + V A + + + S +TGL+PG +Y ++++
Sbjct: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1886
Query: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
S A T ID+P NL T N+ VSW P +A I Y++ Y RE
Sbjct: 1887 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1946
Query: 841 VPVGKEQSST--VLTGLRPGMEYTVHVWAQKGNQESK 875
V T +TGL PG EYT++V A K NQ+S+
Sbjct: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
Score = 240 bits (612), Expect = 7e-63
Identities = 226/820 (27%), Positives = 353/820 (43%), Gaps = 53/820 (6%)
Query: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
Query: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
Query: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
Query: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
Query: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
Query: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
Query: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
Query: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
+QSS L PG+EY V V+ K ++ES + P +L + + V+W
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTW 1287
Query: 906 -DPVQATIDKYMVRYTSADGE--TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
P + ++VRY+ E E+ + ++ VLT L PG EY+V V + ES
Sbjct: 1288 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
Query: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGTVKEMQLG 1020
+ +T LD P + S +T + + W P A I GY + + + G +E ++
Sbjct: 1348 TPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
Query: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
L L G Y VS+VA G S + STV
Sbjct: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV 1447
Score = 223 bits (567), Expect = 1e-57
Identities = 210/764 (27%), Positives = 332/764 (43%), Gaps = 55/764 (7%)
Query: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
Query: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Query: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
Query: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
Query: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
Query: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
Query: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
Query: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
Query: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
Query: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
Query: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
T +G+ + E V + SS L PG+EY V V+ K +ES + PP
Sbjct: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP 1270
Query: 977 RNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQ 1033
+LR + + +TW PPS + +++ Y + V E+ + D L L
Sbjct: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
Query: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
G Y VS+ + S + T G P D S + NS
Sbjct: 1331 GTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
Score = 192 bits (487), Expect = 2e-48
Identities = 168/669 (25%), Positives = 281/669 (42%), Gaps = 60/669 (8%)
Query: 261 QVVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
++ P +Q+ ++S+ V W PSS V Y ++ P K +Q I
Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
GL P +Y+V++ S P A T++ TD +S+ + WE+P +V
Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1660
Query: 380 YYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNG 439
Y++ Y + ++ P + ++ GL PG+EY ++VV + ++E +P++
Sbjct: 1661 RYRVTYS--SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
Query: 440 RTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD--GDTKEMAVHKDESSTV 497
T I +PT++ +VT + + W P + Y VR T + G KE+ + D SS V
Sbjct: 1719 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1778
Query: 498 LTGLKPGEAYKVYVWAERGNQGSKKAD--TNALTEIDSPANLVTDRVTENTATISWDPVQ 555
++GL Y+V V+A + S+ A L + P TE T TISW
Sbjct: 1779 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1838
Query: 556 ATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
TI + V A+ Q + + + S +TGL+PG +Y ++++ + S +
Sbjct: 1839 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1898
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSST-- 673
A T ID+P NL T N VSW P +A I Y+++Y G REV T
Sbjct: 1899 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1958
Query: 674 VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRA 733
+TGL PG EY ++V A K +Q+S+ + +T +P
Sbjct: 1959 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP---------------------- 1996
Query: 734 TIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKA 793
V + G ++P +G +P V + ++ + G + + T
Sbjct: 1997 -----FVTHPGYDTGNGIQLP--------GTSGQQPSVGQQM-IFEEHGFRRTTPPTTAT 2042
Query: 794 ---QTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV--HYTSANGETREVPVGKEQS 848
P N+ + +++ T+SW P Q T Y++ H + E + V +
Sbjct: 2043 PIRHRPRPYPPNVGQEALSQ--TTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTST 2099
Query: 849 STVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPV 908
S LTGL G Y + V A K Q K + E+ N V + + + +DP
Sbjct: 2100 SATLTGLTRGATYNIIVEALKDQQRH-----KVREEVVTVGNSVNEGLNQPTDDSCFDPY 2154
Query: 909 QATIDKYMV 917
T+ Y V
Sbjct: 2155 --TVSHYAV 2161
Score = 37.0 bits (84), Expect = 0.12
Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 14/127 (11%)
Query: 534 PANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPG 593
P N+ + +++ T ISW P Q T + + + D+E + V +S LTGL G
Sbjct: 2052 PPNVGQEALSQTT--ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2109
Query: 594 VEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVR 653
Y + V A K D++ K T V + V E + + D + D Y V
Sbjct: 2110 ATYNIIVEALK-DQQRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVS 2157
Query: 654 YTSAGGE 660
+ + G E
Sbjct: 2158 HYAVGDE 2164
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 315 bits (806), Expect = 2e-85
Identities = 238/810 (29%), Positives = 379/810 (46%), Gaps = 28/810 (3%)
Query: 265 PQGLQLLKNTEDSLL-VSWEPSSQVD--HYLLSYYPL-GKELSGKQIQVPKEQHSYEILG 320
P L L N + +L VSWE S+ D Y ++ P G++ + + V +Q S
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
Query: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVD 379
L PG +Y V++ VK++ S P + T+ +++ V W P S ++
Sbjct: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
Query: 380 YYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
+ +RY P+ +E VAE+++ S + +T L PGTEY ++V + + E P+
Sbjct: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
Query: 439 GRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESST 496
+T +DSPT + +T ++ TV W +A I Y +R+ G +E V +S
Sbjct: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
LT L PG Y V + A G + S T D P +L T + ISWD
Sbjct: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV 1473
Query: 557 TIDKYVVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KK 611
T+ Y + Y + + +E V +S+ ++GL+PGV+YT+ V+A G +S K
Sbjct: 1474 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKE 669
N T+ID P + V +N +V W P + + Y V T + G T+ G +
Sbjct: 1534 ISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
Query: 670 QSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWD 729
Q+ + GL+P +EY+V V+AQ ES+ A T+ID P+ L V + ++W+
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
Query: 730 PVRATIDRYVVRYTSAKDG--ETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
+ + RY V Y+S +DG E P G+E ++ L GLRPG EYTV V A ES+
Sbjct: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALHDDMESQ 1712
Query: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGETREVPVGK 845
T I +P +L VT + + W P + Y V T G +E+ +
Sbjct: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDWVTENMATV 903
+ SS V++GL +Y V V+A K S+ A T + P+ TE T+
Sbjct: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1832
Query: 904 SWDPVQATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
SW TI + V A+G+T + + + S +TGL+PG +Y ++++ S
Sbjct: 1833 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1892
Query: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGRE 1022
A T +D P NLR A T + +++W PP A+I GYI+ Y+ P +E+
Sbjct: 1893 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1952
Query: 1023 D--QRFALQGLEQGATYPVSLVAFKGGRRS 1050
+ GLE G Y + ++A K ++S
Sbjct: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
Score = 313 bits (801), Expect = 9e-85
Identities = 226/760 (29%), Positives = 348/760 (45%), Gaps = 31/760 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1386
Query: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 1387 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1442
Query: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 1443 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1502
Query: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 1503 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1562
Query: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
Query: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREV---PVG 667
A T+ID PK L V + ++W+ Q + +Y V Y+S E+ P G
Sbjct: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1682
Query: 668 KEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVS 727
+E ++ L GLRPG EY V V A D ES+ T I +P +L +VT +
Sbjct: 1683 EEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
Query: 728 WDPVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
W P + Y VR T K G +E+ + + SS V++GL +Y V V+A K S
Sbjct: 1742 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
Query: 787 KKADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPV 843
+ A T ++ P+ TE T T+SW TI + V ANG+T + +
Sbjct: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1861
Query: 844 GKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATV 903
+ S +TGL+PG +Y ++++ N S A T ID P NL T N V
Sbjct: 1862 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1921
Query: 904 SWDPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQE 961
SW P +A I Y+++Y REV T +TGL PG EY ++V A K Q+
Sbjct: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
Query: 962 S------KKADTKAQTELDPPRNLRPSAVTQSGGILTWTP 995
S KK D Q P NL + + TP
Sbjct: 1982 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTP 2021
Score = 304 bits (778), Expect = 4e-82
Identities = 240/848 (28%), Positives = 381/848 (44%), Gaps = 35/848 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
Query: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
Query: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Query: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGE--TREVPVGK 668
+ P +L + + V+W P + + ++VRY+ E E+ +
Sbjct: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
Query: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSW 728
++ VLT L PG EY+V V + ES + +T +DSP + +T N TV W
Sbjct: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
Query: 729 DPVRATIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
RATI Y +R+ G RE V ++S LT L PG EY V + A G +ES
Sbjct: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1438
Query: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGK 845
+ T D P++L T + +SWD T+ Y + Y T N +E V
Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDGPKNLVTDWVTENMA 901
+S+ ++GL+PG++YT+ V+A G + SK +TEID P + V +N
Sbjct: 1499 SKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI 1558
Query: 902 TVSWDPVQATIDKYMVRYT--SADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
+V W P + + Y V T + G T+ G + + + GL+P +EY+V V+AQ +
Sbjct: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
Query: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEM-- 1017
ES+ A T +D P+ L + V + W P Q+ Y +TY P+ + E+
Sbjct: 1619 GESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
Query: 1018 QLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
E+ LQGL G+ Y VS+VA S+ + T ST P P+D Q
Sbjct: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA---IPAPTDLKFTQVTP 1735
Query: 1078 NAASGLYT 1085
+ S +T
Sbjct: 1736 TSLSAQWT 1743
Score = 276 bits (706), Expect = 9e-74
Identities = 242/848 (28%), Positives = 371/848 (43%), Gaps = 60/848 (7%)
Query: 255 TGLDCAQVVTPQGLQLLKNTEDSLLVSW-EPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
TGLD +P G+ T +S V W P + + Y + ++P ++ +VP +
Sbjct: 1356 TGLD-----SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
Query: 314 HSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN 373
+S + L PGT+Y+V++ + S +T V V T SL + W+
Sbjct: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
Query: 374 PSTEVDYYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGE--- 429
P+ V YY++ YG G V E TVP S KS I+GL PG +Y ITV + G
Sbjct: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTGRGDS 1527
Query: 430 -LEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT--SADGDTKE 486
KPI +N RTEID P+ + V +++ +V W P + + Y V T + G TK
Sbjct: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1587
Query: 487 MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENT 546
D++ + GL+P Y V V+A+ + S+ A+T ID P L V ++
Sbjct: 1588 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS 1647
Query: 547 ATISWDPVQATIDKYVVRYTSADD--QETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604
I+W+ Q + +Y V Y+S +D E G+E ++ L GLRPG EYTV V A
Sbjct: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALH 1706
Query: 605 GDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETR 662
D ES+ T I +P +L +VT + W P + Y VR T G +
Sbjct: 1707 DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766
Query: 663 EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVT 720
E+ + + SS V++GL +Y V V+A K S+ A T ++ P+ T
Sbjct: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
E T+SW TI + V A + + + S +TGL+PG +Y ++++
Sbjct: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1886
Query: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
S A T ID+P NL T N+ VSW P +A I Y++ Y RE
Sbjct: 1887 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1946
Query: 841 VPVGKEQSST--VLTGLRPGMEYTVHVWAQKGNQES------KKADTKAQTEIDGPKNLV 892
V T +TGL PG EYT++V A K NQ+S KK D Q NL
Sbjct: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLH 2006
Query: 893 TDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVH 952
+ + +TV P V + D G +G +P + +
Sbjct: 2007 GPEILDVPSTVQKTP--------FVTHPGYD-------TGNGIQLPGTSGQQPSVGQQM- 2050
Query: 953 VWAQKGAQESKKADTKAQTELDP---PRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQF 1009
++ + G + + T P P N+ A++Q+ ++W P YI++
Sbjct: 2051 IFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQT--TISWA-PFQDTSEYIISCH- 2106
Query: 1010 PDGTVKE---MQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSR---NVSTTLSTVGAR 1063
P GT +E ++ L GL +GATY + + A K +R + V T ++V
Sbjct: 2107 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 2166
Query: 1064 FPHPSDCS 1071
P+D S
Sbjct: 2167 LNQPTDDS 2174
Score = 240 bits (612), Expect = 7e-63
Identities = 226/820 (27%), Positives = 353/820 (43%), Gaps = 53/820 (6%)
Query: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
Query: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
Query: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
Query: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
Query: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
Query: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
Query: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
Query: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
+QSS L PG+EY V V+ K ++ES + P +L + + V+W
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTW 1287
Query: 906 -DPVQATIDKYMVRYTSADGE--TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
P + ++VRY+ E E+ + ++ VLT L PG EY+V V + ES
Sbjct: 1288 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
Query: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGTVKEMQLG 1020
+ +T LD P + S +T + + W P A I GY + + + G +E ++
Sbjct: 1348 TPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
Query: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
L L G Y VS+VA G S + STV
Sbjct: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV 1447
Score = 223 bits (567), Expect = 1e-57
Identities = 210/764 (27%), Positives = 332/764 (43%), Gaps = 55/764 (7%)
Query: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
Query: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Query: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
Query: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
Query: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
Query: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
Query: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
Query: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
Query: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
Query: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
Query: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
T +G+ + E V + SS L PG+EY V V+ K +ES + PP
Sbjct: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP 1270
Query: 977 RNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQ 1033
+LR + + +TW PPS + +++ Y + V E+ + D L L
Sbjct: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
Query: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
G Y VS+ + S + T G P D S + NS
Sbjct: 1331 GTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
Score = 157 bits (398), Expect = 5e-38
Identities = 145/579 (25%), Positives = 246/579 (42%), Gaps = 41/579 (7%)
Query: 265 PQGLQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLP 323
P+GL DS+ ++WE P QV Y ++Y + E+ + E+ GL P
Sbjct: 1635 PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRP 1694
Query: 324 GTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDYYKL 383
G++Y V++ + +++ S P +T + T T SL +W P+ ++ Y++
Sbjct: 1695 GSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1754
Query: 384 RYGPM--TGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPI--LLNG 439
R P TG + E+ + S S ++GL T+Y+++V ++ L +P ++
Sbjct: 1755 RVTPKEKTGP-MKEINLAPDS---SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT 1810
Query: 440 RTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTK-EMAVHKDESSTVL 498
+ P TE T T+SW I + V A+G T + + D S +
Sbjct: 1811 LENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1870
Query: 499 TGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATI 558
TGL+PG YK+Y++ N S +A T ID+P+NL T N+ +SW P +A I
Sbjct: 1871 TGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARI 1930
Query: 559 DKYVVRYTSADDQETREVLVGKEQSST--VLTGLRPGVEYTVHVWAQKGDRES-----KK 611
Y+++Y REV+ T +TGL PG EYT++V A K +++S +K
Sbjct: 1931 TGYIIKYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 1989
Query: 612 ADTNAPTDIDSPK-NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQ 670
P + P NL + + +TV P +V G ++P Q
Sbjct: 1990 KTDELPQLVTLPHPNLHGPEILDVPSTVQKTP-------FVTHPGYDTGNGIQLPGTSGQ 2042
Query: 671 SSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDP 730
+V G + + + A P N+ + +++ T+SW P
Sbjct: 2043 QPSV------GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQT--TISWAP 2094
Query: 731 VRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKAD 790
+ T + + + D E + V +S LTGL G Y + V A K Q
Sbjct: 2095 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH---- 2150
Query: 791 TKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV 829
K + ++ + N V + + + T +DP T+ Y V
Sbjct: 2151 -KVREEVVTVGNSVNEGLNQPTDDSCFDPY--TVSHYAV 2186
Score = 84.7 bits (208), Expect = 5e-16
Identities = 100/413 (24%), Positives = 170/413 (41%), Gaps = 51/413 (12%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEILG 320
V P+ ++ TE ++ +SW ++ + + + P + + Q + + SY I G
Sbjct: 1814 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITG 1872
Query: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDY 380
L PGT Y + L + + SSP + A+T + T NSL V W+ P +
Sbjct: 1873 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1932
Query: 381 YKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGR 440
Y ++Y G EV VP+ + ITGL PGTEY I V+ ++ + +P++ GR
Sbjct: 1933 YIIKY-EKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLI--GR 1988
Query: 441 TEIDSPTNVVT--------DRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKD 492
+ D +VT + + +TV P + + G +
Sbjct: 1989 KKTDELPQLVTLPHPNLHGPEILDVPSTVQKTP-----------FVTHPGYDTGNGIQLP 2037
Query: 493 ESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDS-----PANLVTDRVTENTA 547
+S G +P ++ ++ E G + + T T I P N+ + +++ T
Sbjct: 2038 GTS----GQQPSVGQQM-IFEEHGFRRTTPPTT--ATPIRHRPRPYPPNVGQEALSQTT- 2089
Query: 548 TISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDR 607
ISW P Q T + + + D+E + V +S LTGL G Y + V A K D+
Sbjct: 2090 -ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALK-DQ 2147
Query: 608 ESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGE 660
+ K T V + V E + + D + D Y V + + G E
Sbjct: 2148 QRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVSHYAVGDE 2189
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 300 bits (767), Expect = 8e-81
Identities = 236/826 (28%), Positives = 376/826 (45%), Gaps = 35/826 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
Query: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
Query: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Query: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGE--TREVPVGK 668
+ P +L + + V+W P + + ++VRY+ E E+ +
Sbjct: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
Query: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSW 728
++ VLT L PG EY+V V + ES + +T +DSP + +T N TV W
Sbjct: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
Query: 729 DPVRATIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
RATI Y +R+ G RE V ++S LT L PG EY V + A G +ES
Sbjct: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1438
Query: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGK 845
+ T D P++L T + +SWD T+ Y + Y T N +E V
Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDGPKNLVTDWVTENMA 901
+S+ ++GL+PG++YT+ V+A G + SK +TEID P + V +N
Sbjct: 1499 SKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI 1558
Query: 902 TVSWDPVQATIDKYMVRYT--SADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
+V W P + + Y V T + G T+ G + + + GL+P +EY+V V+AQ +
Sbjct: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
Query: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGY--ILTYQFPDGTVKEM 1017
ES+ A T + P +L+ + VT + WTPP+ Q+ GY +T + G +KE+
Sbjct: 1619 GESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678
Query: 1018 QLGREDQRFALQGLEQGATYPVSLVAFKG---GRRSRNVSTTLSTV 1060
L + + GL Y VS+ A K R ++ V TTL V
Sbjct: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1724
Score = 296 bits (757), Expect = 1e-79
Identities = 221/818 (27%), Positives = 369/818 (45%), Gaps = 28/818 (3%)
Query: 254 FTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
FT L + P ++ TE +++++W P+ ++ L G E +V +
Sbjct: 1082 FTTLQPGSSIPPYNTEV---TETTIVITWTPAPRIGFKLGVRPSQGGEAPR---EVTSDS 1135
Query: 314 HSYEILGLLPGTKYIVTLRNVKN-EVSSSPQHLLATTDLAVLGTAWVTDETENS-LDVEW 371
S + GL PG +Y+ T++ +++ + +P T L+ + + L V W
Sbjct: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
Query: 372 ENPST-EVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGEL 430
E +T ++ Y++ P GQ+ + +D +S L PG EY ++V ++ +
Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-QSSCTFDNLSPGLEYNVSVYTVKDDK 1254
Query: 431 EGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAV-IDKYVVRYTSA--DGDTKEM 487
E PI + PT++ + DT V+W P ++ + ++VRY+ + D E+
Sbjct: 1255 ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1314
Query: 488 AVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTA 547
++ +++ VLT L PG Y V V + S T +DSP + +T N+
Sbjct: 1315 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1374
Query: 548 TISWDPVQATIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGD 606
T+ W +ATI Y +R+ RE V ++S LT L PG EY V + A G
Sbjct: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
Query: 607 RESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGET--REV 664
ES T D P++L T +SWD + Y + Y GG + +E
Sbjct: 1435 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
Query: 665 PVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQES----KKADTKAQTDIDSPQNLVTDRVT 720
V +S+ ++GL+PG++Y + V+A G +S K +T+ID P + V
Sbjct: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKD-GETREVPVGKEQSSTVLTGLRPGVEYTVHVWA 779
+N +V W P + + Y V T G T+ G +Q+ + GL+P VEY V V+A
Sbjct: 1555 DNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1614
Query: 780 QKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGE 837
Q + ES+ A T I +P +L VT + + W P + Y V T G
Sbjct: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674
Query: 838 TREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDW 895
+E+ + + SS V++GL +Y V V+A K S+ A T + P+
Sbjct: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734
Query: 896 VTENMATVSWDPVQATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVW 954
TE T+SW TI + V A+G+T + + + S +TGL+PG +Y ++++
Sbjct: 1735 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
Query: 955 AQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTV 1014
S A T +D P NLR A T + +++W PP A+I GYI+ Y+ P
Sbjct: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1854
Query: 1015 KEMQLGRED--QRFALQGLEQGATYPVSLVAFKGGRRS 1050
+E+ + GLE G Y + ++A K ++S
Sbjct: 1855 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
Score = 288 bits (736), Expect = 3e-77
Identities = 225/758 (29%), Positives = 346/758 (45%), Gaps = 30/758 (3%)
Query: 265 PQGLQLLKNTEDSLL-VSWEPSSQVD--HYLLSYYPL-GKELSGKQIQVPKEQHSYEILG 320
P L L N + +L VSWE S+ D Y ++ P G++ + + V +Q S
Sbjct: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
Query: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVD 379
L PG +Y V++ VK++ S P + T+ +++ V W P S ++
Sbjct: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
Query: 380 YYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
+ +RY P+ +E VAE+++ S + +T L PGTEY ++V + + E P+
Sbjct: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
Query: 439 GRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESST 496
+T +DSPT + +T ++ TV W +A I Y +R+ G +E V +S
Sbjct: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
LT L PG Y V + A G + S T D P +L T + ISWD
Sbjct: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV 1473
Query: 557 TIDKYVVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KK 611
T+ Y + Y + + +E V +S+ ++GL+PGV+YT+ V+A G +S K
Sbjct: 1474 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKE 669
N T+ID P + V +N +V W P + + Y V T + G T+ G +
Sbjct: 1534 ISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
Query: 670 QSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWD 729
Q+ + GL+P +EY+V V+AQ ES+ A T I +P +L +VT + W
Sbjct: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWT 1653
Query: 730 PVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKK 788
P + Y VR T K G +E+ + + SS V++GL +Y V V+A K S+
Sbjct: 1654 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1713
Query: 789 ADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPVGK 845
A T ++ P+ TE T T+SW TI + V ANG+T + +
Sbjct: 1714 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP 1773
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
+ S +TGL+PG +Y ++++ N S A T ID P NL T N VSW
Sbjct: 1774 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 1833
Query: 906 DPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQES- 962
P +A I Y+++Y REV T +TGL PG EY ++V A K Q+S
Sbjct: 1834 QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1893
Query: 963 -----KKADTKAQTELDPPRNLRPSAVTQSGGILTWTP 995
KK D Q P NL + + TP
Sbjct: 1894 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTP 1931
Score = 263 bits (671), Expect = 1e-69
Identities = 183/640 (28%), Positives = 294/640 (45%), Gaps = 21/640 (3%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1386
Query: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 1387 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1442
Query: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 1443 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1502
Query: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 1503 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1562
Query: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
Query: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGK 668
A T I +P +L +VT + W P + Y VR T G +E+ +
Sbjct: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1682
Query: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVTENMATV 726
+ SS V++GL +Y V V+A K S+ A T ++ P+ TE T+
Sbjct: 1683 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1742
Query: 727 SWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
SW TI + V A + + + S +TGL+PG +Y ++++ S
Sbjct: 1743 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1802
Query: 787 KKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKE 846
A T ID+P NL T N+ VSW P +A I Y++ Y REV
Sbjct: 1803 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1862
Query: 847 QSST--VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE 884
T +TGL PG EYT++V A K NQ+S+ + +T+
Sbjct: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 1902
Score = 240 bits (612), Expect = 7e-63
Identities = 226/820 (27%), Positives = 353/820 (43%), Gaps = 53/820 (6%)
Query: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
Query: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
Query: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
Query: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
Query: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
Query: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
Query: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
Query: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
+QSS L PG+EY V V+ K ++ES + P +L + + V+W
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTW 1287
Query: 906 -DPVQATIDKYMVRYTSADGE--TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
P + ++VRY+ E E+ + ++ VLT L PG EY+V V + ES
Sbjct: 1288 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
Query: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGTVKEMQLG 1020
+ +T LD P + S +T + + W P A I GY + + + G +E ++
Sbjct: 1348 TPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
Query: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
L L G Y VS+VA G S + STV
Sbjct: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV 1447
Score = 223 bits (567), Expect = 1e-57
Identities = 210/764 (27%), Positives = 332/764 (43%), Gaps = 55/764 (7%)
Query: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
Query: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Query: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
Query: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
Query: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
Query: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
Query: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
Query: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
Query: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
Query: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
Query: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
T +G+ + E V + SS L PG+EY V V+ K +ES + PP
Sbjct: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP 1270
Query: 977 RNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQ 1033
+LR + + +TW PPS + +++ Y + V E+ + D L L
Sbjct: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
Query: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
G Y VS+ + S + T G P D S + NS
Sbjct: 1331 GTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
Score = 145 bits (366), Expect = 2e-34
Identities = 149/599 (24%), Positives = 243/599 (40%), Gaps = 42/599 (7%)
Query: 261 QVVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
++ P +Q+ ++S+ V W PSS V Y ++ P K +Q I
Sbjct: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
GL P +Y+V++ S P A T + T T SL +W P+ ++
Sbjct: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLT 1660
Query: 380 YYKLRYGPM--TGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPI-- 435
Y++R P TG + E+ + S S ++GL T+Y+++V ++ L +P
Sbjct: 1661 GYRVRVTPKEKTGP-MKEINLAPDS---SSVVVSGLMVATKYEVSVYALKDTLTSRPAQG 1716
Query: 436 LLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTK-EMAVHKDES 494
++ + P TE T T+SW I + V A+G T + + D
Sbjct: 1717 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVR 1776
Query: 495 STVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPV 554
S +TGL+PG YK+Y++ N S +A T ID+P+NL T N+ +SW P
Sbjct: 1777 SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 1836
Query: 555 QATIDKYVVRYTSADDQETREVLVGKEQSST--VLTGLRPGVEYTVHVWAQKGDRES--- 609
+A I Y+++Y REV+ T +TGL PG EYT++V A K +++S
Sbjct: 1837 RARITGYIIKYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1895
Query: 610 --KKADTNAPTDIDSPK-NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVP- 665
+K P + P NL + + +TV P G + + P
Sbjct: 1896 IGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 1955
Query: 666 VGKEQ-----------SSTVLTGLRPGME-YMVHVWAQKGDQESKKADTKAQTDIDSP-- 711
VG++ T T +R Y +V + + D P
Sbjct: 1956 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGL 2015
Query: 712 -QNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPG 770
N T + + T+SW P + T + + + D E + V +S LTGL G
Sbjct: 2016 NPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2075
Query: 771 VEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV 829
Y + V A K Q K + ++ + N V + + + T +DP T+ Y V
Sbjct: 2076 ATYNIIVEALKDQQRH-----KVREEVVTVGNSVNEGLNQPTDDSCFDPY--TVSHYAV 2127
Score = 79.3 bits (194), Expect = 2e-14
Identities = 100/425 (23%), Positives = 161/425 (37%), Gaps = 44/425 (10%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEILG 320
V P+ ++ TE ++ +SW ++ + + + P + + Q + + SY I G
Sbjct: 1724 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITG 1782
Query: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDY 380
L PGT Y + L + + SSP + A+T + T NSL V W+ P +
Sbjct: 1783 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 1842
Query: 381 YKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPIL---- 436
Y ++Y G EV VP+ + ITGL PGTEY I V+ ++ + +P++
Sbjct: 1843 YIIKY-EKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1900
Query: 437 --------------LNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG 482
L+G +D P+ V + T +D + + G
Sbjct: 1901 TDELPQLVTLPHPNLHGPEILDVPSTV---QKTPFVTHPGYDTGNGIQLPGTSGQQPSVG 1957
Query: 483 DTKEMAVHKDESSTVLTGLKP----GEAYKVYVWAERGNQGSKKADTNALTEIDSPA--- 535
H +T T P Y V E + D + P
Sbjct: 1958 QQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNP 2017
Query: 536 NLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVE 595
N T + + TISW P Q T + + + D+E + V +S LTGL G
Sbjct: 2018 NASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 2077
Query: 596 YTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT 655
Y + V A K D++ K T V + V E + + D + D Y V +
Sbjct: 2078 YNIIVEALK-DQQRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVSHY 2125
Query: 656 SAGGE 660
+ G E
Sbjct: 2126 AVGDE 2130
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 300 bits (767), Expect = 8e-81
Identities = 236/826 (28%), Positives = 376/826 (45%), Gaps = 35/826 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
Query: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
Query: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Query: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
Query: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
Query: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGE--TREVPVGK 668
+ P +L + + V+W P + + ++VRY+ E E+ +
Sbjct: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
Query: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSW 728
++ VLT L PG EY+V V + ES + +T +DSP + +T N TV W
Sbjct: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
Query: 729 DPVRATIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787
RATI Y +R+ G RE V ++S LT L PG EY V + A G +ES
Sbjct: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1438
Query: 788 KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGK 845
+ T D P++L T + +SWD T+ Y + Y T N +E V
Sbjct: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDGPKNLVTDWVTENMA 901
+S+ ++GL+PG++YT+ V+A G + SK +TEID P + V +N
Sbjct: 1499 SKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI 1558
Query: 902 TVSWDPVQATIDKYMVRYT--SADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
+V W P + + Y V T + G T+ G + + + GL+P +EY+V V+AQ +
Sbjct: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
Query: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGY--ILTYQFPDGTVKEM 1017
ES+ A T + P +L+ + VT + WTPP+ Q+ GY +T + G +KE+
Sbjct: 1619 GESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1678
Query: 1018 QLGREDQRFALQGLEQGATYPVSLVAFKG---GRRSRNVSTTLSTV 1060
L + + GL Y VS+ A K R ++ V TTL V
Sbjct: 1679 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1724
Score = 296 bits (757), Expect = 1e-79
Identities = 221/818 (27%), Positives = 369/818 (45%), Gaps = 28/818 (3%)
Query: 254 FTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
FT L + P ++ TE +++++W P+ ++ L G E +V +
Sbjct: 1082 FTTLQPGSSIPPYNTEV---TETTIVITWTPAPRIGFKLGVRPSQGGEAPR---EVTSDS 1135
Query: 314 HSYEILGLLPGTKYIVTLRNVKN-EVSSSPQHLLATTDLAVLGTAWVTDETENS-LDVEW 371
S + GL PG +Y+ T++ +++ + +P T L+ + + L V W
Sbjct: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
Query: 372 ENPST-EVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGEL 430
E +T ++ Y++ P GQ+ + +D +S L PG EY ++V ++ +
Sbjct: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-QSSCTFDNLSPGLEYNVSVYTVKDDK 1254
Query: 431 EGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAV-IDKYVVRYTSA--DGDTKEM 487
E PI + PT++ + DT V+W P ++ + ++VRY+ + D E+
Sbjct: 1255 ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1314
Query: 488 AVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTA 547
++ +++ VLT L PG Y V V + S T +DSP + +T N+
Sbjct: 1315 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1374
Query: 548 TISWDPVQATIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGD 606
T+ W +ATI Y +R+ RE V ++S LT L PG EY V + A G
Sbjct: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
Query: 607 RESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGET--REV 664
ES T D P++L T +SWD + Y + Y GG + +E
Sbjct: 1435 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
Query: 665 PVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQES----KKADTKAQTDIDSPQNLVTDRVT 720
V +S+ ++GL+PG++Y + V+A G +S K +T+ID P + V
Sbjct: 1495 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1554
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKD-GETREVPVGKEQSSTVLTGLRPGVEYTVHVWA 779
+N +V W P + + Y V T G T+ G +Q+ + GL+P VEY V V+A
Sbjct: 1555 DNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1614
Query: 780 QKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGE 837
Q + ES+ A T I +P +L VT + + W P + Y V T G
Sbjct: 1615 QNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP 1674
Query: 838 TREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDW 895
+E+ + + SS V++GL +Y V V+A K S+ A T + P+
Sbjct: 1675 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTD 1734
Query: 896 VTENMATVSWDPVQATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVW 954
TE T+SW TI + V A+G+T + + + S +TGL+PG +Y ++++
Sbjct: 1735 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
Query: 955 AQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTV 1014
S A T +D P NLR A T + +++W PP A+I GYI+ Y+ P
Sbjct: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1854
Query: 1015 KEMQLGRED--QRFALQGLEQGATYPVSLVAFKGGRRS 1050
+E+ + GLE G Y + ++A K ++S
Sbjct: 1855 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892
Score = 279 bits (713), Expect = 1e-74
Identities = 207/721 (28%), Positives = 326/721 (45%), Gaps = 34/721 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1386
Query: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 1387 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1442
Query: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 1443 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1502
Query: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 1503 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1562
Query: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
Query: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGK 668
A T I +P +L +VT + W P + Y VR T G +E+ +
Sbjct: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1682
Query: 669 EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVTENMATV 726
+ SS V++GL +Y V V+A K S+ A T ++ P+ TE T+
Sbjct: 1683 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1742
Query: 727 SWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
SW TI + V A + + + S +TGL+PG +Y ++++ S
Sbjct: 1743 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1802
Query: 787 KKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKE 846
A T ID+P NL T N+ VSW P +A I Y++ Y REV
Sbjct: 1803 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1862
Query: 847 QSST--VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVS 904
T +TGL PG EYT++V A K NQ+S+ + +T G + L + T+S
Sbjct: 1863 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT---GQEAL-------SQTTIS 1912
Query: 905 WDPVQATIDKYMV--RYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
W P Q T +Y++ D E + V +S LTGL G Y + V A K Q
Sbjct: 1913 WAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH 1971
Query: 963 K 963
K
Sbjct: 1972 K 1972
Score = 240 bits (612), Expect = 7e-63
Identities = 226/820 (27%), Positives = 353/820 (43%), Gaps = 53/820 (6%)
Query: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
Query: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
Query: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
Query: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
Query: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
Query: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Query: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
Query: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
Query: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
Query: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
Query: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
+QSS L PG+EY V V+ K ++ES + P +L + + V+W
Sbjct: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTW 1287
Query: 906 -DPVQATIDKYMVRYTSADGE--TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962
P + ++VRY+ E E+ + ++ VLT L PG EY+V V + ES
Sbjct: 1288 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
Query: 963 KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGTVKEMQLG 1020
+ +T LD P + S +T + + W P A I GY + + + G +E ++
Sbjct: 1348 TPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
Query: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060
L L G Y VS+VA G S + STV
Sbjct: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV 1447
Score = 223 bits (567), Expect = 1e-57
Identities = 210/764 (27%), Positives = 332/764 (43%), Gaps = 55/764 (7%)
Query: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
Query: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Query: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
Query: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
Query: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
Query: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
Query: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
Query: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
Query: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
Query: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
Query: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
T +G+ + E V + SS L PG+EY V V+ K +ES + PP
Sbjct: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP 1270
Query: 977 RNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQ 1033
+LR + + +TW PPS + +++ Y + V E+ + D L L
Sbjct: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
Query: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077
G Y VS+ + S + T G P D S + NS
Sbjct: 1331 GTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
Score = 216 bits (550), Expect = 1e-55
Identities = 163/577 (28%), Positives = 261/577 (45%), Gaps = 32/577 (5%)
Query: 265 PQGLQLLKNTEDSLLVSWE-PSSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLP 323
P+ L+++ T SLL+SW+ P+ V +Y ++Y G ++ VP + + I GL P
Sbjct: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510
Query: 324 GTKYIVTLRNVKNE----VSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
G Y +T+ V SS P + T++ VTD +NS+ V+W S+ V
Sbjct: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVT 1570
Query: 380 YYKLRYGPMTGQEVAEVTVPKSSDP-KSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Y++ P G T K++ P ++ I GL P EY ++V E +P++
Sbjct: 1571 GYRVTTTPKNGPGP---TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
Query: 439 GRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD--GDTKEMAVHKDESST 496
T I +PT++ +VT + + W P + Y VR T + G KE+ + D SS
Sbjct: 1628 AVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1687
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKAD--TNALTEIDSPANLVTDRVTENTATISWDPV 554
V++GL Y+V V+A + S+ A L + P TE T TISW
Sbjct: 1688 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1747
Query: 555 QATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADT 614
TI + V A+ Q + + + S +TGL+PG +Y ++++ + S
Sbjct: 1748 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1807
Query: 615 NAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSST- 673
+A T ID+P NL T N VSW P +A I Y+++Y G REV T
Sbjct: 1808 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1867
Query: 674 -VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVR 732
+TGL PG EY ++V A K +Q+S+ + +T ++ + T+SW P +
Sbjct: 1868 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA----------LSQTTISWAPFQ 1917
Query: 733 ATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792
T + + + D E + V +S LTGL G Y + V A K Q K
Sbjct: 1918 DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH-----K 1972
Query: 793 AQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV 829
+ ++ + N V + + + T +DP T+ Y V
Sbjct: 1973 VREEVVTVGNSVNEGLNQPTDDSCFDPY--TVSHYAV 2007
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 231 bits (590), Expect = 3e-60
Identities = 206/807 (25%), Positives = 337/807 (41%), Gaps = 36/807 (4%)
Query: 265 PQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPL--GKELSGKQIQVPKEQHSYEILGL 321
P L + + T S VSW P S VD Y + YYP+ GK ++ V + + S + L
Sbjct: 224 PSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR---QEFYVSRMETSTVLKDL 280
Query: 322 LPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDYY 381
P T+Y+V + +V + S P T + + + D ++ V+W+ P Y
Sbjct: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ-PVGGATGY 339
Query: 382 KLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRT 441
L Y P+ E + + +T L P TEY +TV + +L +P+ + T
Sbjct: 340 ILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVT 399
Query: 442 -EIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESSTVLTG 500
+ P ++ VT T V W+PV + KY+VRY + + D KE+ V + E+ST L
Sbjct: 400 LPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKD 459
Query: 501 LKPGEAYKVYVWAERGNQGSKKADTNALTE-IDSPANLVTDRVTENTATISWDPVQATID 559
L Y V V A S T + +P NL VT +WD + +
Sbjct: 460 LFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVS 519
Query: 560 KYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKAD------ 613
Y + + + E ++ ++++ V L P Y V + A D ES+ D
Sbjct: 520 LYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPD-ESESDDLIGSER 578
Query: 614 ------TNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETRE--VP 665
T AP P+NL T N TV WDP + KY + Y + GE E
Sbjct: 579 TLPILTTQAPK--SGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 636
Query: 666 VGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT-DIDSPQNLVTDRVTENMA 724
+G Q+S VL L+P Y + V + D E + + +T +++ +NL + +
Sbjct: 637 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL 696
Query: 725 TVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVW-AQKGA 783
V WD +Y + Y A G VP+ + +L L+P YTV V
Sbjct: 697 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG 756
Query: 784 QESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANG--ETREV 841
+ +DT +N+ T N+ V WDP + +Y V Y+ +G + +
Sbjct: 757 DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESI 816
Query: 842 PVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT-EIDGPKNLVTDWVTENM 900
V L L P Y+V++ A + E + + +T GP+NL T N
Sbjct: 817 VVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNS 876
Query: 901 ATVSWDPVQATIDKYMVRYTSADGETRE--VPVGKEHSSTVLTGLRPGMEYMVHVWAQKG 958
+V+WD + +Y + Y+ G+ + V ++ +L L+P Y + V A
Sbjct: 877 LSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYE 936
Query: 959 AQESKKADTKAQT-ELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEM 1017
+ +T L PP+N+ S + ++W P + + GY + Y+ P G+ + M
Sbjct: 937 DGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK-PVGSNEPM 995
Query: 1018 Q-LGREDQRFALQGLEQGATYPVSLVA 1043
+ E + L L TY V++ A
Sbjct: 996 EAFVGEMTSYTLHNLNPSTTYDVNVYA 1022
Score = 189 bits (480), Expect = 1e-47
Identities = 195/765 (25%), Positives = 311/765 (40%), Gaps = 48/765 (6%)
Query: 310 PKEQHSYEILGLLPGTKYIVTLR-NVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLD 368
P + H+Y + ++ + L N+ N V P L A ++L + ++ T S
Sbjct: 186 PDDTHAYNVADFESLSRIVDDLTINLCNSVKG-PGDLEAPSNLVI------SERTHRSFR 238
Query: 369 VEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRG 428
V W PS VD YK+ Y P++G + E V + D L P TEY + V +
Sbjct: 239 VSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD---LKPETEYVVNVYSVVE 295
Query: 429 ELEGKPILLNGRTEIDSPTNVVTDRVTE---DTATVSWDPVQAVIDKYVVRYTSADGDT- 484
+ +P L G TE P VV+ + + T V W PV Y++ Y DT
Sbjct: 296 DEYSEP--LKG-TEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATG-YILSYKPVK-DTE 350
Query: 485 ----KEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALT-EIDSPANLVT 539
KE+ + + LT L P Y V V A + S+ +T + P +L
Sbjct: 351 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 410
Query: 540 DRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVH 599
VT +T + W+PV + KY+VRY +++ +EV V + ++ST L L YTV
Sbjct: 411 RDVTHSTMNVFWEPVPGKVRKYIVRY-KTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVS 469
Query: 600 VWAQKGDRESKKADTNAPT-DIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAG 658
V A + ES T + +P NL VT +WD + + Y + + G
Sbjct: 470 VSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFG 529
Query: 659 GETR-EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKAD----------TKAQTD 707
+ E + ++++ V L P Y V + A D ES+ D Q
Sbjct: 530 SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPD-ESESDDLIGSERTLPILTTQAP 588
Query: 708 IDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRY-TSAKDGETREVPVGKEQSSTVLTG 766
P+NL T N TV WDP + +Y + Y S +G + +G Q+S VL
Sbjct: 589 KSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQK 648
Query: 767 LRPGVEYTVHVWAQKGAQESKKADTKAQT-DIDSPQNLVTDWVTENTATVSWDPVQATID 825
L+P YT+ V + E + + +T +++ +NL + +T V WD +
Sbjct: 649 LKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPR 708
Query: 826 RYVVHYTSANGETRE-VPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE 884
+Y + Y A G E VP+ + +L L+P YTV V + + +T
Sbjct: 709 QYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTL 768
Query: 885 IDG-PKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADG--ETREVPVGKEHSSTVLT 941
+ G +N+ T N V WDP + +Y V Y+ DG + + V L
Sbjct: 769 MRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLE 828
Query: 942 GLRPGMEYMVHVWAQKGAQESKKADTKAQT-ELDPPRNLRPSAVTQSGGILTWTPPSAQI 1000
L P Y V++ A E + + +T PRNLR T + + W +
Sbjct: 829 RLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPV 888
Query: 1001 HGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVA 1043
Y + Y D + + LQ L+ Y ++++A
Sbjct: 889 QQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 933
Score = 163 bits (412), Expect = 1e-39
Identities = 147/546 (26%), Positives = 234/546 (42%), Gaps = 28/546 (5%)
Query: 530 EIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTG 589
++++P+NLV T + +SW P ++D+Y V Y + +E V + ++STVL
Sbjct: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279
Query: 590 LRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDK 649
L+P EY V+V++ D S+ T +L V V W PV A
Sbjct: 280 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATG- 338
Query: 650 YVVRY----TSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQ 705
Y++ Y + +EV +G + LT L P EY V V A D S+ +
Sbjct: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398
Query: 706 T-DIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVL 764
T + PQ+L VT + V W+PV + +Y+VRY + ++ + +EV V + ++ST L
Sbjct: 399 TLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE-DVKEVEVDRSETSTSL 457
Query: 765 TGLRPGVEYTVHVWAQKGAQESKKADTKAQT-DIDSPQNLVTDWVTENTATVSWDPVQAT 823
L YTV V A ES + T + +P NL VT +WD +
Sbjct: 458 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 517
Query: 824 IDRYVVHYTS-ANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKAD---- 878
+ Y + + + + E + ++++ V L P Y V + A + ES+ D
Sbjct: 518 VSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPD-ESESDDLIGS 576
Query: 879 ------TKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETRE--VP 930
Q GP+NL T N TV WDP + KY + Y + GE E
Sbjct: 577 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 636
Query: 931 VGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTE-LDPPRNLRPSAVTQSGG 989
+G +S VL L+P Y + V + E + + +T+ L+ RNLR + S
Sbjct: 637 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL 696
Query: 990 ILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFA-LQGLEQGATYPVSLVAF---- 1044
+ W Y L Y G +E+ + +A L+ L+ +Y V++V
Sbjct: 697 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG 756
Query: 1045 KGGRRS 1050
GGR S
Sbjct: 757 DGGRTS 762
Score = 160 bits (405), Expect = 7e-39
Identities = 162/646 (25%), Positives = 269/646 (41%), Gaps = 30/646 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILG 320
V P L++ + T + +W+ +S V Y +++ P G + I + ++++
Sbjct: 491 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFEN 549
Query: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTA---------WVTDETENSLDVEW 371
L P T Y V++ + + S S + + L +L T V + T NSL V+W
Sbjct: 550 LNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKW 609
Query: 372 ENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELE 431
+ S V Y++ Y P TG+ + T ++ + L P T Y ITV + + E
Sbjct: 610 DPASGRVQKYRITYQPSTGEGNEQTTT--IGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 667
Query: 432 GKPILLNGRTEIDSPTNVVTDRVTEDTAT----VSWDPVQAVIDKYVVRYTSADGDTKEM 487
G + G+T+ P N V + D +T V WD + +Y + Y A G +E+
Sbjct: 668 GGRMTGRGKTK---PLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEEL 724
Query: 488 A-VHKDESSTVLTGLKPGEAYKVYVW-AERGNQGSKKADTNALTEIDSPANLVTDRVTEN 545
+ + + +L L+P +Y V V G + +DT N+ T N
Sbjct: 725 VPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPN 784
Query: 546 TATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTV-LTGLRPGVEYTVHVWAQK 604
+ + WDP + +Y V Y+ D E +V + V L L P Y+V++ A
Sbjct: 785 SLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALY 844
Query: 605 GDRESKKADTNAPT-DIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETRE 663
D E + T P+NL T N +V+WD + +Y + Y+ G+ +
Sbjct: 845 SDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 904
Query: 664 --VPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT-DIDSPQNLVTDRVT 720
V +++ +L L+P Y + V A D + +T + PQN+
Sbjct: 905 EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 964
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
VSWDP + + Y + Y E E VG E +S L L P Y V+V+AQ
Sbjct: 965 YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQ 1023
Query: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANG-ETR 839
+ S + T + +L T + +T V W P +A Y + + A+G +
Sbjct: 1024 YDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATS-YRLKLSPADGTRGQ 1082
Query: 840 EVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEI 885
E+ V ++S TGL P +Y V V+ Q N E K T +
Sbjct: 1083 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTV 1128
Score = 150 bits (378), Expect = 1e-35
Identities = 129/468 (27%), Positives = 202/468 (43%), Gaps = 26/468 (5%)
Query: 617 PTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVR-YTSAGGETREVPVGKEQSSTVL 675
P D+++P NLV T VSW P ++D+Y V Y +GG+ +E V + ++STVL
Sbjct: 218 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 277
Query: 676 TGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATI 735
L+P EY+V+V++ D+ S+ +T +L V V W PV
Sbjct: 278 KDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT 337
Query: 736 DRYVVRYTSAKDGE---TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792
Y++ Y KD E +EV +G + LT L P EY V V A S+ +
Sbjct: 338 G-YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR 396
Query: 793 AQT-DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTV 851
T + PQ+L VT +T V W+PV + +Y+V Y + + +EV V + ++ST
Sbjct: 397 EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS 456
Query: 852 LTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE-IDGPKNLVTDWVTENMATVSWDPVQA 910
L L YTV V A ES + T + P NL VT +WD +
Sbjct: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516
Query: 911 TIDKYMVRYTS-ADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKAD--- 966
+ Y + + + E + + ++ V L P Y V + A ES+ D
Sbjct: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIY-PDESESDDLIG 575
Query: 967 -------TKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQ--FPDGTVKEM 1017
Q PRNL+ T + + W P S ++ Y +TYQ +G +
Sbjct: 576 SERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 635
Query: 1018 QLGREDQRFALQGLEQGATYPVSLVAF----KGGRRS-RNVSTTLSTV 1060
+G LQ L+ Y +++ + +GGR + R + L+TV
Sbjct: 636 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTV 683
Score = 111 bits (277), Expect = 5e-24
Identities = 98/376 (26%), Positives = 157/376 (41%), Gaps = 27/376 (7%)
Query: 266 QGLQLLKNTEDSLLVSWEPS-SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG 324
+ +Q+ T +SL V W+P+ V Y + Y P+ + I VP + L+P
Sbjct: 774 RNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPD 833
Query: 325 TKYIVTLRNVKNEVSSSPQHLLATT-------DLAVLGTAWVTDETENSLDVEWENPSTE 377
T Y V L + ++ +P T +L V G ET NSL V W++
Sbjct: 834 TLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFG------ETTNSLSVAWDHADGP 887
Query: 378 VDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
V Y++ Y P G + E T ++ + L P T YKITV+ + + +G +
Sbjct: 888 VQQYRIIYSPTVGDPIDEYTTVPGR--RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG 945
Query: 438 NGRTE-IDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
NGRT + P N+ VSWDP + + Y + Y + A + +S
Sbjct: 946 NGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSY 1005
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
L L P Y V V+A+ + S T + +L T ++ +T + W P +A
Sbjct: 1006 TLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA 1065
Query: 557 TIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKAD--- 613
Y ++ + AD +E+ V ++S TGL P +Y V V+ Q + E
Sbjct: 1066 A-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKE 1124
Query: 614 ------TNAPTDIDSP 623
T APT+ +P
Sbjct: 1125 HTTVKPTEAPTEPPTP 1140
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 231 bits (590), Expect = 3e-60
Identities = 206/807 (25%), Positives = 337/807 (41%), Gaps = 36/807 (4%)
Query: 265 PQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPL--GKELSGKQIQVPKEQHSYEILGL 321
P L + + T S VSW P S VD Y + YYP+ GK ++ V + + S + L
Sbjct: 1388 PSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR---QEFYVSRMETSTVLKDL 1444
Query: 322 LPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDYY 381
P T+Y+V + +V + S P T + + + D ++ V+W+ P Y
Sbjct: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ-PVGGATGY 1503
Query: 382 KLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRT 441
L Y P+ E + + +T L P TEY +TV + +L +P+ + T
Sbjct: 1504 ILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVT 1563
Query: 442 -EIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESSTVLTG 500
+ P ++ VT T V W+PV + KY+VRY + + D KE+ V + E+ST L
Sbjct: 1564 LPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKD 1623
Query: 501 LKPGEAYKVYVWAERGNQGSKKADTNALTE-IDSPANLVTDRVTENTATISWDPVQATID 559
L Y V V A S T + +P NL VT +WD + +
Sbjct: 1624 LFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVS 1683
Query: 560 KYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKAD------ 613
Y + + + E ++ ++++ V L P Y V + A D ES+ D
Sbjct: 1684 LYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPD-ESESDDLIGSER 1742
Query: 614 ------TNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETRE--VP 665
T AP P+NL T N TV WDP + KY + Y + GE E
Sbjct: 1743 TLPILTTQAPK--SGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800
Query: 666 VGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT-DIDSPQNLVTDRVTENMA 724
+G Q+S VL L+P Y + V + D E + + +T +++ +NL + +
Sbjct: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL 1860
Query: 725 TVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVW-AQKGA 783
V WD +Y + Y A G VP+ + +L L+P YTV V
Sbjct: 1861 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG 1920
Query: 784 QESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANG--ETREV 841
+ +DT +N+ T N+ V WDP + +Y V Y+ +G + +
Sbjct: 1921 DGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESI 1980
Query: 842 PVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT-EIDGPKNLVTDWVTENM 900
V L L P Y+V++ A + E + + +T GP+NL T N
Sbjct: 1981 VVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNS 2040
Query: 901 ATVSWDPVQATIDKYMVRYTSADGETRE--VPVGKEHSSTVLTGLRPGMEYMVHVWAQKG 958
+V+WD + +Y + Y+ G+ + V ++ +L L+P Y + V A
Sbjct: 2041 LSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYE 2100
Query: 959 AQESKKADTKAQT-ELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEM 1017
+ +T L PP+N+ S + ++W P + + GY + Y+ P G+ + M
Sbjct: 2101 DGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK-PVGSNEPM 2159
Query: 1018 Q-LGREDQRFALQGLEQGATYPVSLVA 1043
+ E + L L TY V++ A
Sbjct: 2160 EAFVGEMTSYTLHNLNPSTTYDVNVYA 2186
Score = 189 bits (480), Expect = 1e-47
Identities = 195/765 (25%), Positives = 311/765 (40%), Gaps = 48/765 (6%)
Query: 310 PKEQHSYEILGLLPGTKYIVTLR-NVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLD 368
P + H+Y + ++ + L N+ N V P L A ++L + ++ T S
Sbjct: 1350 PDDTHAYNVADFESLSRIVDDLTINLCNSVKG-PGDLEAPSNLVI------SERTHRSFR 1402
Query: 369 VEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRG 428
V W PS VD YK+ Y P++G + E V + D L P TEY + V +
Sbjct: 1403 VSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD---LKPETEYVVNVYSVVE 1459
Query: 429 ELEGKPILLNGRTEIDSPTNVVTDRVTE---DTATVSWDPVQAVIDKYVVRYTSADGDT- 484
+ +P L G TE P VV+ + + T V W PV Y++ Y DT
Sbjct: 1460 DEYSEP--LKG-TEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATG-YILSYKPVK-DTE 1514
Query: 485 ----KEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALT-EIDSPANLVT 539
KE+ + + LT L P Y V V A + S+ +T + P +L
Sbjct: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574
Query: 540 DRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVH 599
VT +T + W+PV + KY+VRY +++ +EV V + ++ST L L YTV
Sbjct: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRY-KTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVS 1633
Query: 600 VWAQKGDRESKKADTNAPT-DIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAG 658
V A + ES T + +P NL VT +WD + + Y + + G
Sbjct: 1634 VSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFG 1693
Query: 659 GETR-EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKAD----------TKAQTD 707
+ E + ++++ V L P Y V + A D ES+ D Q
Sbjct: 1694 SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPD-ESESDDLIGSERTLPILTTQAP 1752
Query: 708 IDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRY-TSAKDGETREVPVGKEQSSTVLTG 766
P+NL T N TV WDP + +Y + Y S +G + +G Q+S VL
Sbjct: 1753 KSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQK 1812
Query: 767 LRPGVEYTVHVWAQKGAQESKKADTKAQT-DIDSPQNLVTDWVTENTATVSWDPVQATID 825
L+P YT+ V + E + + +T +++ +NL + +T V WD +
Sbjct: 1813 LKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPR 1872
Query: 826 RYVVHYTSANGETRE-VPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE 884
+Y + Y A G E VP+ + +L L+P YTV V + + +T
Sbjct: 1873 QYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTL 1932
Query: 885 IDG-PKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADG--ETREVPVGKEHSSTVLT 941
+ G +N+ T N V WDP + +Y V Y+ DG + + V L
Sbjct: 1933 MRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLE 1992
Query: 942 GLRPGMEYMVHVWAQKGAQESKKADTKAQT-ELDPPRNLRPSAVTQSGGILTWTPPSAQI 1000
L P Y V++ A E + + +T PRNLR T + + W +
Sbjct: 1993 RLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPV 2052
Query: 1001 HGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVA 1043
Y + Y D + + LQ L+ Y ++++A
Sbjct: 2053 QQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 2097
Score = 180 bits (456), Expect = 9e-45
Identities = 153/541 (28%), Positives = 240/541 (44%), Gaps = 24/541 (4%)
Query: 263 VTPQGLQLLKNTEDSLLVSWEPSSQVDHYLLSYYPLGKELSGKQ---IQVPKEQHSYEIL 319
V P+ L + T +W P+ + + SY+ KE +G + P S +
Sbjct: 633 VPPKDLSFSEVTSYGFKTNWSPAGE---NVFSYHITYKEAAGDDEVTVVEPASSTSVVLS 689
Query: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAW---VTDETENSLDVEWENPST 376
L P T Y+V + + S P TT+ V G VTDET +S + W
Sbjct: 690 SLKPETLYLVNVTAEYEDGFSIPLAGEETTE-EVKGAPRNLKVTDETTDSFKITWTQAPG 748
Query: 377 EVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPIL 436
V Y++ Y P+ G E EVT P + + R + L P T+Y+++V+P G P+
Sbjct: 749 RVLRYRIIYRPVAGGESREVTTPPN---QRRRTLENLIPDTKYEVSVIPEYFSGPGTPLT 805
Query: 437 LNGRTE--IDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTS-ADGDTKEMAVHKDE 493
N TE +P ++ T T +SW + +Y+V YT A G+T+E+ V D
Sbjct: 806 GNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDT 865
Query: 494 SSTVLTGLKPGEAYKVYVWA--ERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
++TVL GLK G Y + V A G + + L E SP +LVT +T+ + W
Sbjct: 866 TNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYW 925
Query: 552 DPVQATIDKYVVRYTSA-DDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
+ Y V + S DD +T E + ++ T++ L+P +Y + V+A E +
Sbjct: 926 TSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGE 985
Query: 611 KADTNAPTDI-DSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAG-GETREVPVGK 668
+A T++ K L D TEN V+W P + Y V Y G G+ V
Sbjct: 986 PLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPP 1045
Query: 669 EQSSTVLTGLRPGMEYMVHVWA--QKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATV 726
+STVL L+P Y + V + G+ + ++ + SP+NL T T + V
Sbjct: 1046 TVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRV 1105
Query: 727 SWDPVRATIDRYVVRY-TSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE 785
+W+P + Y V + + D E+ VG ++ VL LR G Y V+V+ E
Sbjct: 1106 TWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
Query: 786 S 786
S
Sbjct: 1166 S 1166
Score = 177 bits (448), Expect = 8e-44
Identities = 149/544 (27%), Positives = 239/544 (43%), Gaps = 18/544 (3%)
Query: 534 PANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPG 593
P +L VT +W P + Y + Y A + V+ +S VL+ L+P
Sbjct: 635 PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPE 694
Query: 594 VEYTVHVWAQKGDRESKKADTNAPTDI--DSPKNL-VTDRVTENMATVSWDPVQAAIDKY 650
Y V+V A+ D S T+ +P+NL VTD T++ ++W + +Y
Sbjct: 695 TLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFK-ITWTQAPGRVLRY 753
Query: 651 VVRYTS-AGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDI- 708
+ Y AGGE+REV Q L L P +Y V V + A T+
Sbjct: 754 RIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEV 813
Query: 709 -DSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGL 767
+P++L T + +SW + +Y+V YT GET+EV V + ++TVL GL
Sbjct: 814 RGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGL 873
Query: 768 RPGVEYTVHVWA--QKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATID 825
+ G +Y + V A GA ++ + + SPQ+LVT +T+ + W +
Sbjct: 874 KEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVR 933
Query: 826 RYVVHYTSA--NGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT 883
Y V + S + +T E + ++ T++ L+P +Y + V+A + E + A T
Sbjct: 934 GYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATT 993
Query: 884 EI-DGPKNLVTDWVTENMATVSWDPVQATIDKYMVRY-TSADGETREVPVGKEHSSTVLT 941
E+ K L D TEN V+W P + Y V Y G+ V +STVL
Sbjct: 994 ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLK 1053
Query: 942 GLRPGMEYMVHVWA--QKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQ 999
L+P Y + V + G + ++ + PRNL+ S T S +TW P +
Sbjct: 1054 RLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGE 1113
Query: 1000 IHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVA-FKGGRRSRNVSTT 1056
+ GY +T+ D + E+ +G D L+ L G TY V++ F GG S V
Sbjct: 1114 VKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQE 1173
Query: 1057 LSTV 1060
++T+
Sbjct: 1174 MTTL 1177
Score = 163 bits (412), Expect = 1e-39
Identities = 147/546 (26%), Positives = 234/546 (42%), Gaps = 28/546 (5%)
Query: 530 EIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTG 589
++++P+NLV T + +SW P ++D+Y V Y + +E V + ++STVL
Sbjct: 1384 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 1443
Query: 590 LRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDK 649
L+P EY V+V++ D S+ T +L V V W PV A
Sbjct: 1444 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATG- 1502
Query: 650 YVVRY----TSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQ 705
Y++ Y + +EV +G + LT L P EY V V A D S+ +
Sbjct: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562
Query: 706 T-DIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVL 764
T + PQ+L VT + V W+PV + +Y+VRY + ++ + +EV V + ++ST L
Sbjct: 1563 TLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE-DVKEVEVDRSETSTSL 1621
Query: 765 TGLRPGVEYTVHVWAQKGAQESKKADTKAQT-DIDSPQNLVTDWVTENTATVSWDPVQAT 823
L YTV V A ES + T + +P NL VT +WD +
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
Query: 824 IDRYVVHYTS-ANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKAD---- 878
+ Y + + + + E + ++++ V L P Y V + A + ES+ D
Sbjct: 1682 VSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPD-ESESDDLIGS 1740
Query: 879 ------TKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETRE--VP 930
Q GP+NL T N TV WDP + KY + Y + GE E
Sbjct: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800
Query: 931 VGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTE-LDPPRNLRPSAVTQSGG 989
+G +S VL L+P Y + V + E + + +T+ L+ RNLR + S
Sbjct: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTL 1860
Query: 990 ILTWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFA-LQGLEQGATYPVSLVAF---- 1044
+ W Y L Y G +E+ + +A L+ L+ +Y V++V
Sbjct: 1861 NVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEG 1920
Query: 1045 KGGRRS 1050
GGR S
Sbjct: 1921 DGGRTS 1926
Score = 160 bits (405), Expect = 7e-39
Identities = 162/646 (25%), Positives = 269/646 (41%), Gaps = 30/646 (4%)
Query: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILG 320
V P L++ + T + +W+ +S V Y +++ P G + I + ++++
Sbjct: 1655 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFEN 1713
Query: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTA---------WVTDETENSLDVEW 371
L P T Y V++ + + S S + + L +L T V + T NSL V+W
Sbjct: 1714 LNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKW 1773
Query: 372 ENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELE 431
+ S V Y++ Y P TG+ + T ++ + L P T Y ITV + + E
Sbjct: 1774 DPASGRVQKYRITYQPSTGEGNEQTTT--IGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 1831
Query: 432 GKPILLNGRTEIDSPTNVVTDRVTEDTAT----VSWDPVQAVIDKYVVRYTSADGDTKEM 487
G + G+T+ P N V + D +T V WD + +Y + Y A G +E+
Sbjct: 1832 GGRMTGRGKTK---PLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEEL 1888
Query: 488 A-VHKDESSTVLTGLKPGEAYKVYVW-AERGNQGSKKADTNALTEIDSPANLVTDRVTEN 545
+ + + +L L+P +Y V V G + +DT N+ T N
Sbjct: 1889 VPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPN 1948
Query: 546 TATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTV-LTGLRPGVEYTVHVWAQK 604
+ + WDP + +Y V Y+ D E +V + V L L P Y+V++ A
Sbjct: 1949 SLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALY 2008
Query: 605 GDRESKKADTNAPT-DIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETRE 663
D E + T P+NL T N +V+WD + +Y + Y+ G+ +
Sbjct: 2009 SDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPID 2068
Query: 664 --VPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT-DIDSPQNLVTDRVT 720
V +++ +L L+P Y + V A D + +T + PQN+
Sbjct: 2069 EYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEW 2128
Query: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
VSWDP + + Y + Y E E VG E +S L L P Y V+V+AQ
Sbjct: 2129 YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQ 2187
Query: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANG-ETR 839
+ S + T + +L T + +T V W P +A Y + + A+G +
Sbjct: 2188 YDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATS-YRLKLSPADGTRGQ 2246
Query: 840 EVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEI 885
E+ V ++S TGL P +Y V V+ Q N E K T +
Sbjct: 2247 EITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292
Score = 151 bits (382), Expect = 3e-36
Identities = 135/530 (25%), Positives = 221/530 (41%), Gaps = 19/530 (3%)
Query: 360 TDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEY 419
++ T W V Y + Y G + V P SS + ++ L P T Y
Sbjct: 641 SEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASS---TSVVLSSLKPETLY 697
Query: 420 KITVVPMRGELEGKPILLNGRTEI--DSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRY 477
+ V + P+ TE +P N+ T D+ ++W + +Y + Y
Sbjct: 698 LVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIY 757
Query: 478 TS-ADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEI--DSP 534
A G+++E+ ++ L L P Y+V V E + NA TE +P
Sbjct: 758 RPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNP 817
Query: 535 ANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGV 594
+L T +T +SW + +Y+V YT ET+EV V + ++TVL GL+ G
Sbjct: 818 RDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGT 877
Query: 595 EYTVHVWA--QKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVV 652
+Y + V A G ++ + + SP++LVT +T+ W + Y V
Sbjct: 878 QYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRV 937
Query: 653 RYTSA--GGETREVPVGKEQSSTVLTGLRPGMEYMVHVWA--QKGDQESKKADTKAQTDI 708
+ S +T E + ++ T++ L+P +Y + V+A G+ E D +
Sbjct: 938 SWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQ 997
Query: 709 DSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLR 768
DS + L D TEN V+W P + Y V Y G+ V +STVL L+
Sbjct: 998 DS-KTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQ 1056
Query: 769 PGVEYTVHVWA--QKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDR 826
P Y + V + G + ++ + SP+NL T T ++ V+W+P +
Sbjct: 1057 PQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKG 1116
Query: 827 YVV--HYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQES 874
Y V H T + E+ VG ++ VL LR G Y V+V+ ES
Sbjct: 1117 YKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
Score = 150 bits (378), Expect = 1e-35
Identities = 129/468 (27%), Positives = 202/468 (43%), Gaps = 26/468 (5%)
Query: 617 PTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVR-YTSAGGETREVPVGKEQSSTVL 675
P D+++P NLV T VSW P ++D+Y V Y +GG+ +E V + ++STVL
Sbjct: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441
Query: 676 TGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATI 735
L+P EY+V+V++ D+ S+ +T +L V V W PV
Sbjct: 1442 KDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT 1501
Query: 736 DRYVVRYTSAKDGE---TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792
Y++ Y KD E +EV +G + LT L P EY V V A S+ +
Sbjct: 1502 G-YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR 1560
Query: 793 AQT-DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTV 851
T + PQ+L VT +T V W+PV + +Y+V Y + + +EV V + ++ST
Sbjct: 1561 EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS 1620
Query: 852 LTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE-IDGPKNLVTDWVTENMATVSWDPVQA 910
L L YTV V A ES + T + P NL VT +WD +
Sbjct: 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 1680
Query: 911 TIDKYMVRYTS-ADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKAD--- 966
+ Y + + + E + + ++ V L P Y V + A ES+ D
Sbjct: 1681 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIY-PDESESDDLIG 1739
Query: 967 -------TKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQ--FPDGTVKEM 1017
Q PRNL+ T + + W P S ++ Y +TYQ +G +
Sbjct: 1740 SERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799
Query: 1018 QLGREDQRFALQGLEQGATYPVSLVAF----KGGRRS-RNVSTTLSTV 1060
+G LQ L+ Y +++ + +GGR + R + L+TV
Sbjct: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTV 1847
Score = 111 bits (277), Expect = 5e-24
Identities = 98/376 (26%), Positives = 157/376 (41%), Gaps = 27/376 (7%)
Query: 266 QGLQLLKNTEDSLLVSWEPS-SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG 324
+ +Q+ T +SL V W+P+ V Y + Y P+ + I VP + L+P
Sbjct: 1938 RNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPD 1997
Query: 325 TKYIVTLRNVKNEVSSSPQHLLATT-------DLAVLGTAWVTDETENSLDVEWENPSTE 377
T Y V L + ++ +P T +L V G ET NSL V W++
Sbjct: 1998 TLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFG------ETTNSLSVAWDHADGP 2051
Query: 378 VDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
V Y++ Y P G + E T ++ + L P T YKITV+ + + +G +
Sbjct: 2052 VQQYRIIYSPTVGDPIDEYTTVPGR--RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTG 2109
Query: 438 NGRTE-IDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
NGRT + P N+ VSWDP + + Y + Y + A + +S
Sbjct: 2110 NGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSY 2169
Query: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
L L P Y V V+A+ + S T + +L T ++ +T + W P +A
Sbjct: 2170 TLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA 2229
Query: 557 TIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKAD--- 613
Y ++ + AD +E+ V ++S TGL P +Y V V+ Q + E
Sbjct: 2230 A-TSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKE 2288
Query: 614 ------TNAPTDIDSP 623
T APT+ +P
Sbjct: 2289 HTTVKPTEAPTEPPTP 2304
Score = 63.5 bits (153), Expect = 1e-09
Identities = 104/477 (21%), Positives = 176/477 (36%), Gaps = 71/477 (14%)
Query: 620 IDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKEQSSTVLTG 677
++ P NL+ V+ ++W+P + + Y V T +AG + VG + ++ +
Sbjct: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
Query: 678 LRPGMEYMVHVWAQKGDQES-------KKADTKAQTDIDSPQNLVTDRV-----TENMAT 725
L EY + V A KG S K K Q + ++ D V + ++
Sbjct: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGI 453
Query: 726 VSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWA------ 779
++ VRA ++ V + E+ + Q S V P E+T+ +
Sbjct: 454 ANFVKVRAFLEVLVKSF---------EISPNRVQISLVQYSRDPHTEFTLKKFTKVEDII 504
Query: 780 --------QKGAQESKKADTKAQTDIDSPQN-----------LVTDWVTENTATVSWDPV 820
+ G+ + KA T + I P L+TD + + DP
Sbjct: 505 EAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFR---DPA 561
Query: 821 ----QATIDRYVVHYTSANGETREVPVGKEQSSTVLT------GLRPGMEYTVHVWAQKG 870
+ ++ + V A E + V T R E T + +
Sbjct: 562 IKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSI-CLRI 620
Query: 871 NQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVP 930
QE KA PK+L VT +W P + Y + Y A G+ EV
Sbjct: 621 EQELAAIKKKAYVP---PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDD-EVT 676
Query: 931 VGKEHSST--VLTGLRPGMEYMVHVWA--QKGAQESKKADTKAQTELDPPRNLRPSAVTQ 986
V + SST VL+ L+P Y+V+V A + G + + PRNL+ + T
Sbjct: 677 VVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETT 736
Query: 987 SGGILTWTPPSAQIHGYILTYQ-FPDGTVKEMQLGREDQRFALQGLEQGATYPVSLV 1042
+TWT ++ Y + Y+ G +E+ +R L+ L Y VS++
Sbjct: 737 DSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVI 793
Score = 46.2 bits (108), Expect = 2e-04
Identities = 76/406 (18%), Positives = 141/406 (34%), Gaps = 57/406 (14%)
Query: 530 EIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTG 589
E+D P++L + ENT +SW I Y + D T+E + + T+L+
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
Query: 590 LRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDR----VTENMATVSWDPVQA 645
L P EY V + + ES S V + + + +W +
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVF 143
Query: 646 AID----------KYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGD- 694
+D KY++ + +A ++ K + V E+ ++ + Q+ +
Sbjct: 144 LVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDEL 203
Query: 695 -QESKKADTKAQTDI--DSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETR 751
KK K + D+ LV + TE+ R + + T K +
Sbjct: 204 LAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAG------ARVGFPKVAIIITDGKSQDEV 257
Query: 752 EVP------VGKEQSSTVLTGL----------RPGVEYTVHV---------------WAQ 780
E+P VG E S + P + + +V
Sbjct: 258 EIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVC 317
Query: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
G E + ++ P NL+ V+ ++W+P + + Y V T +R+
Sbjct: 318 SGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQ 377
Query: 841 --VPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE 884
+ VG + ++ + L EY + V A KG S+ +T+
Sbjct: 378 HALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQ 423
Score = 39.3 bits (90), Expect = 0.025
Identities = 22/82 (26%), Positives = 37/82 (45%)
Query: 705 QTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVL 764
+ ++D P +L + EN +SW I Y + DG T+E + + T+L
Sbjct: 22 EAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLL 81
Query: 765 TGLRPGVEYTVHVWAQKGAQES 786
+ L P EY V + + +ES
Sbjct: 82 SELVPETEYVVTITSYDEVEES 103
Score = 39.3 bits (90), Expect = 0.025
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 882 QTEIDGPKNLVTDWVTENMATVSW-DPVQATIDKYMVRYTSADGETREVPVGKEHSSTVL 940
+ E+D P +L + EN +SW PV + + + DG T+E + + T+L
Sbjct: 22 EAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLL 81
Query: 941 TGLRPGMEYMVHVWAQKGAQES 962
+ L P EY+V + + +ES
Sbjct: 82 SELVPETEYVVTITSYDEVEES 103
Score = 38.5 bits (88), Expect = 0.042
Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Query: 432 GKPILLNG-RTEIDSPTNVVTDRVTEDTATVSW-DPVQAVIDKYVVRYTSADGDTKEMAV 489
G +LL+ E+D P+++ + E+T +SW PV ++ + + DG TKE +
Sbjct: 13 GAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL 72
Query: 490 HKDESSTVLTGLKPGEAYKVYV 511
+ T+L+ L P Y V +
Sbjct: 73 SASTTETLLSELVPETEYVVTI 94
Score = 38.5 bits (88), Expect = 0.042
Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 794 QTDIDSPQNLVTDWVTENTATVSW-DPVQATIDRYVVHYTSANGETREVPVGKEQSSTVL 852
+ ++D P +L + ENT +SW PV + + + +G T+E + + T+L
Sbjct: 22 EAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLL 81
Query: 853 TGLRPGMEYTVHVWAQKGNQES 874
+ L P EY V + + +ES
Sbjct: 82 SELVPETEYVVTITSYDEVEES 103
Score = 35.4 bits (80), Expect = 0.36
Identities = 28/113 (24%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 246 GECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPS-SQVDHYLLSYYPLGKELSG 304
GE +G +G ++ +P+ L+ T S V+WEP+ +V Y ++++P G +
Sbjct: 1072 GEGKLRQG-SGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRL 1130
Query: 305 KQIQVPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSP---QHLLATTDLAVL 354
++ V ++ + L GT Y V + + + SSP Q + +D V+
Sbjct: 1131 GELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVM 1183
Score = 33.5 bits (75), Expect = 1.4
Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 1/76 (1%)
Query: 970 QTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQ-FPDGTVKEMQLGREDQRFAL 1028
+ E+DPP +L + ++ ++W P I GY +T DG KE L L
Sbjct: 22 EAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLL 81
Query: 1029 QGLEQGATYPVSLVAF 1044
L Y V++ ++
Sbjct: 82 SELVPETEYVVTITSY 97
Score = 33.1 bits (74), Expect = 1.8
Identities = 19/88 (21%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 436 LLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESS 495
L++G ++ P+N++ V+ ++W+P + + Y V T +++ A+ +
Sbjct: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
Query: 496 TVLT--GLKPGEAYKVYVWAERGNQGSK 521
T L+ L Y++ V A +G S+
Sbjct: 387 TTLSVRDLSADTEYQISVSAMKGMTSSE 414
Score = 30.8 bits (68), Expect = 8.8
Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 364 ENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITV 423
EN++ + W P + Y++ P T E T+ S+ + ++ L P TEY +T+
Sbjct: 38 ENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST---TETLLSELVPETEYVVTI 94
Query: 424 VPMRGELEGKPIL 436
E P++
Sbjct: 95 TSYDEVEESVPVI 107
>gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]
Length = 275
Score = 199 bits (507), Expect = 1e-50
Identities = 100/216 (46%), Positives = 135/216 (62%), Gaps = 11/216 (5%)
Query: 1067 PSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRW 1126
P C + + SG +TIYL RPL V CDM+TDGGGW VFQRR G +DF++ W
Sbjct: 64 PRTCKDLLDRGHFLSGWHTIYLPD--CRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDW 121
Query: 1127 RSYVEGFGDPMKEFWLGLDKLHNLTT-GTPARYEVRVDLQTANES-AYAIYDFFQVASSK 1184
+Y +GFG + EFWLG D +H LT GT E+RVDL ++ +A Y F+VA
Sbjct: 122 ATYKQGFGSRLGEFWLGNDNIHALTAQGTS---ELRVDLVDFEDNYQFAKYRSFKVADEA 178
Query: 1185 ERYKLTVGKY-RGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPN 1243
E+Y L +G + G+AGD+LT+HN F+T D+DND+ NCA+ G WWYKNCH++N N
Sbjct: 179 EKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLN 238
Query: 1244 GRYGETKH---SEGVNWEPWKGHEFSIPYVELKIRP 1276
GRY H + G+NW+ KG+ +S E+K+RP
Sbjct: 239 GRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRP 274
>gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]
Length = 313
Score = 199 bits (507), Expect = 1e-50
Identities = 100/216 (46%), Positives = 135/216 (62%), Gaps = 11/216 (5%)
Query: 1067 PSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRW 1126
P C + + SG +TIYL RPL V CDM+TDGGGW VFQRR G +DF++ W
Sbjct: 102 PRTCKDLLDRGHFLSGWHTIYLPD--CRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDW 159
Query: 1127 RSYVEGFGDPMKEFWLGLDKLHNLTT-GTPARYEVRVDLQTANES-AYAIYDFFQVASSK 1184
+Y +GFG + EFWLG D +H LT GT E+RVDL ++ +A Y F+VA
Sbjct: 160 ATYKQGFGSRLGEFWLGNDNIHALTAQGTS---ELRVDLVDFEDNYQFAKYRSFKVADEA 216
Query: 1185 ERYKLTVGKY-RGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPN 1243
E+Y L +G + G+AGD+LT+HN F+T D+DND+ NCA+ G WWYKNCH++N N
Sbjct: 217 EKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLN 276
Query: 1244 GRYGETKH---SEGVNWEPWKGHEFSIPYVELKIRP 1276
GRY H + G+NW+ KG+ +S E+K+RP
Sbjct: 277 GRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRP 312
>gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 198 bits (504), Expect = 2e-50
Identities = 106/240 (44%), Positives = 143/240 (59%), Gaps = 22/240 (9%)
Query: 1047 GRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIY-LHGDASRPLQVYCDMETD 1105
G R R +T G+R P DC V + G+Y+++ H A QVYCDM TD
Sbjct: 229 GTRPRGCAT-----GSR---PRDCLDVLLSGQQDDGVYSVFPTHYPAG--FQVYCDMRTD 278
Query: 1106 GGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQ 1165
GGGW VFQRR G ++FF+ W +Y +GFG E WLGL ++H LTT A YE+ VDL+
Sbjct: 279 GGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTT--QAAYELHVDLE 336
Query: 1166 T-ANESAYAIYD-----FFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDI 1219
N +AYA Y F V ++ Y LTV Y GTAGD+L H+G +FTT DRD+D
Sbjct: 337 DFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDH 396
Query: 1220 ALSNCALTHHGGWWYKNCHLANPNGRY---GETKHSEGVNWEPWKGHEFSIPYVELKIRP 1276
+ +NCA + G WWY+NCH +N NG+Y +++GV W W G ++S+ + E+KIRP
Sbjct: 397 SENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRP 456
>gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 198 bits (504), Expect = 2e-50
Identities = 106/240 (44%), Positives = 143/240 (59%), Gaps = 22/240 (9%)
Query: 1047 GRRSRNVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIY-LHGDASRPLQVYCDMETD 1105
G R R +T G+R P DC V + G+Y+++ H A QVYCDM TD
Sbjct: 229 GTRPRGCAT-----GSR---PRDCLDVLLSGQQDDGVYSVFPTHYPAG--FQVYCDMRTD 278
Query: 1106 GGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQ 1165
GGGW VFQRR G ++FF+ W +Y +GFG E WLGL ++H LTT A YE+ VDL+
Sbjct: 279 GGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTT--QAAYELHVDLE 336
Query: 1166 T-ANESAYAIYD-----FFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDI 1219
N +AYA Y F V ++ Y LTV Y GTAGD+L H+G +FTT DRD+D
Sbjct: 337 DFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDH 396
Query: 1220 ALSNCALTHHGGWWYKNCHLANPNGRY---GETKHSEGVNWEPWKGHEFSIPYVELKIRP 1276
+ +NCA + G WWY+NCH +N NG+Y +++GV W W G ++S+ + E+KIRP
Sbjct: 397 SENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRP 456
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 198 bits (504), Expect = 2e-50
Identities = 180/694 (25%), Positives = 295/694 (42%), Gaps = 52/694 (7%)
Query: 391 QEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPTNVV 450
QE+A + P S+ + + +H E + R E + + I + PT ++
Sbjct: 303 QEIA--SEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELI 360
Query: 451 TDRVTEDTATVSWDPVQAVIDKY-VVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKV 509
T VT + V+W ++KY VV Y + G E+ V SSTVL L Y++
Sbjct: 361 TSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQI 420
Query: 510 YVWAERGNQGSK-KADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRY--- 565
V+A + S+ T + ++L+ VTEN+ + WD V Y++ Y
Sbjct: 421 AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SGYLILYAPL 479
Query: 566 TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTNAPT-DIDSPK 624
T + +E+ +G+ + L+GL P EYTV V+A G+ S T + P+
Sbjct: 480 TEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPR 539
Query: 625 NLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGG-ETREVPVGKEQSSTVLTGLRPGME 683
NL V N A ++WDP I+ Y + Y +A G E EV V ++ L GL P E
Sbjct: 540 NLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEV-DPITTFPLKGLTPLTE 598
Query: 684 YMVHVWAQKGDQESKKADTKAQT-DIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRY 742
Y + +++ + +S+ T ++ + Q L D VT + V+W P+ A + + +
Sbjct: 599 YTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMW 658
Query: 743 TSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDS--- 799
G+T EV + +EQ S V+ GL PG EY V + A + T T +DS
Sbjct: 659 IPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWT 718
Query: 800 -------------------PQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
+NLV T ++ V WD + + ++ V Y +A G+ E
Sbjct: 719 EPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEE 778
Query: 841 VPVGK-----EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT-EIDGPKNLVTD 894
+G Q++ +L L P EY V V + E +T GP+NL
Sbjct: 779 EVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVS 838
Query: 895 WVTENMATVSWDPVQATIDKYMVRY--TSADGETREVPVGKEHSSTVLTGLRPGMEYMVH 952
N ++WDP + + Y + Y S G T E VG + ++ ++T L GM+Y V
Sbjct: 839 EEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVK 898
Query: 953 VWAQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQ---- 1008
++A + + S +T NL+ V + W Q+H + Y+
Sbjct: 899 IFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHW-----QVHRHATAYRVVIE 953
Query: 1009 -FPDGTVKEMQLGREDQRFALQGLEQGATYPVSL 1041
D +E +G R GL+ + Y +S+
Sbjct: 954 SLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISV 987
Score = 182 bits (463), Expect = 1e-45
Identities = 173/660 (26%), Positives = 274/660 (41%), Gaps = 43/660 (6%)
Query: 356 TAWVTDE-TENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLH 414
T +T E T S V W + V+ Y++ Y P G + EV V + ++ L
Sbjct: 357 TELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSL- 415
Query: 415 PGTEYKITVVPMRGELEGKPILLNGRT-EIDSPTNVVTDRVTEDTATVSWDPVQAVIDKY 473
TEY+I V + + + T + ++++ VTE++ V WD V Y
Sbjct: 416 --TEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SGY 472
Query: 474 VVRYTSAD----GDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALT 529
++ Y GD KEM + + + L+GL P Y V V+A G + S T
Sbjct: 473 LILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETT 532
Query: 530 -EIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLT 588
+ P NL V N+A ++WDP I+ Y + Y +AD E EV V ++ L
Sbjct: 533 LALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDPI-TTFPLK 591
Query: 589 GLRPGVEYTVHVWAQKGDRESKKADTNAPTD-IDSPKNLVTDRVTENMATVSWDPVQAAI 647
GL P EYT+ +++ + +S+ T+ + + + L D VT + V+W P+ A
Sbjct: 592 GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651
Query: 648 DKYVVRYTSA-GGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT 706
+ + + GG+T EV + +EQ S V+ GL PG EY V + A D + T T
Sbjct: 652 GLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGT 711
Query: 707 DIDS----------------------PQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
+DS +NLV T + V WD + + ++ V Y +
Sbjct: 712 TLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMT 771
Query: 745 AKDGETREV----PVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDS- 799
A+ EV V Q++ +L L P EY V V E +T S
Sbjct: 772 AQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSG 831
Query: 800 PQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGKEQSSTVLTGLRP 857
PQNL N ++WDP + + Y + Y S G T E VG + ++ ++T L
Sbjct: 832 PQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLS 891
Query: 858 GMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMV 917
GM+Y V ++A + + S +T G NL V W + +V
Sbjct: 892 GMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHATAYRVV 951
Query: 918 RYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPR 977
+ D + +E VG + GL+P EY + V+ + E +T+ P R
Sbjct: 952 IESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLPTR 1011
Score = 179 bits (453), Expect = 2e-44
Identities = 154/560 (27%), Positives = 240/560 (42%), Gaps = 42/560 (7%)
Query: 522 KADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKE 581
KA +A+T P L+T VT + ++W ++KY V Y + EV+V
Sbjct: 346 KASAHAIT--GPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGT 403
Query: 582 QSSTVLTGLRPGVEYTVHVWAQKGDRESKKA-DTNAPTDIDSPKNLVTDRVTENMATVSW 640
SSTVL L EY + V+A S+ T + +L+ VTEN V W
Sbjct: 404 VSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKW 463
Query: 641 DPVQAAIDKYVVRYT----SAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQE 696
D V A Y++ Y G+ +E+ +G+ + L+GL P EY V V+A G++
Sbjct: 464 DAVPGA-SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEA 522
Query: 697 SKKADTKAQT-DIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPV 755
S + T + P+NL V N A ++WDP I+ Y + Y +A E EV V
Sbjct: 523 SDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEV 582
Query: 756 GKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTD-IDSPQNLVTDWVTENTAT 814
++ L GL P EYT+ +++ +S+ T+ + + Q L D VT ++
Sbjct: 583 DPI-TTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFR 641
Query: 815 VSWDPVQATIDRYVVHYTSA-NGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQE 873
V+W P+ A + + + G+T EV + +EQ S V+ GL PG EY V + A +
Sbjct: 642 VTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGS 701
Query: 874 SKKADTKAQTEID----------------------GPKNLVTDWVTENMATVSWDPVQAT 911
+ T T +D G +NLV T + V WD +
Sbjct: 702 ESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSD 761
Query: 912 IDKYMVRYTSADGETREVPVGK-----EHSSTVLTGLRPGMEYMVHVWAQKGAQESKKAD 966
+ ++ V Y +A G+ E +G ++ +L L P EY V V E
Sbjct: 762 VQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVS 821
Query: 967 TKAQT-ELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQ--FPDGTVKEMQLGRED 1023
+T P+NLR S + +TW PPS+ + GY + Y+ G E +G +
Sbjct: 822 APGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADI 881
Query: 1024 QRFALQGLEQGATYPVSLVA 1043
+ L G Y V + A
Sbjct: 882 NTILITNLLSGMDYNVKIFA 901
Score = 174 bits (442), Expect = 4e-43
Identities = 167/664 (25%), Positives = 277/664 (41%), Gaps = 45/664 (6%)
Query: 260 AQVVTPQGLQLLKN--TEDSLLVSWEPS-SQVDHYLLSYYPLGKELSGK--QIQVPKEQH 314
A +T +L+ + T S +V+W + V+ Y + YYP GK ++ V
Sbjct: 349 AHAITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTR---GGKPDEVVVDGTVS 405
Query: 315 SYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATT-DLAVLGTAWVTDETENSLDVEWEN 373
S + L+ T+Y + + + +S TT L + + D TENS+ V+W+
Sbjct: 406 STVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDA 465
Query: 374 PSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGK 433
Y L Y P+T + K + + +++GL P TEY +TV M GE
Sbjct: 466 VPGASGYLIL-YAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASD 524
Query: 434 PILLNGRT-EIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKD 492
P+ T + P N+ V ++A ++WDP I+ Y + Y +ADG T+ V D
Sbjct: 525 PVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADG-TEINEVEVD 583
Query: 493 ESSTV-LTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPAN--LVTDRVTENTATI 549
+T L GL P Y + +++ ++G + T T + PA L D VT ++ +
Sbjct: 584 PITTFPLKGLTPLTEYTIAIFSIY-DEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRV 642
Query: 550 SWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES 609
+W P+ A + + + +T EV++ +EQ S V+ GL PG EY V + A D
Sbjct: 643 TWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSE 702
Query: 610 KKADTNAPTDIDS----------------------PKNLVTDRVTENMATVSWDPVQAAI 647
+ T T +DS +NLV T + V WD + +
Sbjct: 703 SEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDV 762
Query: 648 DKYVVRYTSAGGETREVPVGK-----EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADT 702
++ V Y +A G+ E +G Q++ +L L P EY V V D E
Sbjct: 763 QQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSA 822
Query: 703 KAQT-DIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAK-DGETREVPVGKEQS 760
+T PQNL N ++WDP + + Y + Y G T E VG + +
Sbjct: 823 PGKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADIN 882
Query: 761 STVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPV 820
+ ++T L G++Y V ++A + + S +T NL V + W
Sbjct: 883 TILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVH 942
Query: 821 QATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTK 880
+ VV + + + +E VG + GL+P EY + V+ + E
Sbjct: 943 RHATAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIM 1002
Query: 881 AQTE 884
+T+
Sbjct: 1003 EKTQ 1006
Score = 132 bits (333), Expect = 2e-30
Identities = 155/703 (22%), Positives = 280/703 (39%), Gaps = 86/703 (12%)
Query: 442 EIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTG 500
++ PT + + ++ D+ +SW + Y + T ++ G T ++ + + ++ G
Sbjct: 29 QVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQG 88
Query: 501 LKPGEAYKVYVWAERGNQGS-------------KKADTNALTEIDSPANLVTDRVTENTA 547
L P + Y V + A ++ S K+ D ++ N E
Sbjct: 89 LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVK 148
Query: 548 TISWDPVQATI------------------DKYVVRYTSADDQETREVLVGKEQSSTVLTG 589
+ P A I ++ +A D + + +G Q S
Sbjct: 149 FVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSG---- 204
Query: 590 LRPGVEYTVHVWAQKGD-------------------------RESKKADTNAPTDIDSPK 624
P +E+ ++ ++ K + S K + + T +
Sbjct: 205 -DPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIG 263
Query: 625 NLVTD-RVTENMATVSWDPVQAAIDKYVVRYTSAG-GETREVPVGKEQSSTVLTG----- 677
L+TD + +++ S + ++ ++ + + +A E +E+ E ST +
Sbjct: 264 ILITDGKSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEI--ASEPDSTHVYNVAEFD 321
Query: 678 -LRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATID 736
+ +E + + +++ ++ A P L+T VT V+W ++
Sbjct: 322 LMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTELITSEVTARSFMVNWTHAPGNVE 381
Query: 737 RYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK-KADTKAQT 795
+Y V Y + G+ EV V SSTVL L EY + V+A S+ T+
Sbjct: 382 KYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTL 441
Query: 796 DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSAN----GETREVPVGKEQSSTV 851
+ +L+ VTEN+ V WD V Y++ Y G+ +E+ +G+ +
Sbjct: 442 ALPMASDLLLYDVTENSMRVKWDAVPGA-SGYLILYAPLTEGLAGDEKEMKIGETHTDIE 500
Query: 852 LTGLRPGMEYTVHVWAQKGNQESKKADTKAQT-EIDGPKNLVTDWVTENMATVSWDPVQA 910
L+GL P EYTV V+A G + S + T + P+NL V N A ++WDP
Sbjct: 501 LSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSR 560
Query: 911 TIDKYMVRYTSADG-ETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKA 969
I+ Y + Y +ADG E EV V ++ L GL P EY + +++ +S+
Sbjct: 561 QINGYRIVYNNADGTEINEVEV-DPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVF 619
Query: 970 QTELDPPRN-LRPSAVTQSGGILTWTPPSAQ--IHGYILTYQFPDGTVKEMQLGREDQRF 1026
TE P + L VT +TW P SA +H ++ G +E+ L E
Sbjct: 620 TTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLH-KLMWIPVYGGKTEEVVLKEEQDSH 678
Query: 1027 ALQGLEQGATYPVSLVA-FKGGRRSRNVSTTLSTVGARFPHPS 1068
++GLE G Y VSL+A G S V+ +T+ + + P+
Sbjct: 679 VIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPA 721
Score = 40.0 bits (92), Expect = 0.015
Identities = 22/88 (25%), Positives = 38/88 (43%)
Query: 702 TKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSS 761
T Q + P L + ++ + +SW R Y + T G+T ++ + +
Sbjct: 24 TIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATK 83
Query: 762 TVLTGLRPGVEYTVHVWAQKGAQESKKA 789
++ GL P YTV + A +ESK A
Sbjct: 84 AIIQGLMPDQNYTVQIIAYNKDKESKPA 111
Score = 37.7 bits (86), Expect = 0.072
Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 791 TKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT-SANGETREVPVGKEQSS 849
T Q + P L + ++ ++ +SW + Y + T ++ G+T ++ + +
Sbjct: 24 TIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATK 83
Query: 850 TVLTGLRPGMEYTVHVWAQKGNQESKKA 877
++ GL P YTV + A ++ESK A
Sbjct: 84 AIIQGLMPDQNYTVQIIAYNKDKESKPA 111
Score = 37.4 bits (85), Expect = 0.094
Identities = 20/86 (23%), Positives = 38/86 (44%), Gaps = 1/86 (1%)
Query: 967 TKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGY-ILTYQFPDGTVKEMQLGREDQR 1025
T Q ++ PP LR + ++ ++W P + GY +L G ++ L +
Sbjct: 24 TIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATK 83
Query: 1026 FALQGLEQGATYPVSLVAFKGGRRSR 1051
+QGL Y V ++A+ + S+
Sbjct: 84 AIIQGLMPDQNYTVQIIAYNKDKESK 109
Score = 33.9 bits (76), Expect = 1.0
Identities = 20/88 (22%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Query: 879 TKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYT-SADGETREVPVGKEHSS 937
T Q ++ P L + ++ + +SW + Y + T ++ G+T ++ + +
Sbjct: 24 TIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATK 83
Query: 938 TVLTGLRPGMEYMVHVWAQKGAQESKKA 965
++ GL P Y V + A +ESK A
Sbjct: 84 AIIQGLMPDQNYTVQIIAYNKDKESKPA 111
Score = 33.1 bits (74), Expect = 1.8
Identities = 16/72 (22%), Positives = 35/72 (48%), Gaps = 3/72 (4%)
Query: 363 TENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKIT 422
+ +S+ + W+ P + YKL P +G + ++ + ++ ++ I GL P Y +
Sbjct: 42 SHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTA---TKAIIQGLMPDQNYTVQ 98
Query: 423 VVPMRGELEGKP 434
++ + E KP
Sbjct: 99 IIAYNKDKESKP 110
>gi|8051584 ficolin 1 precursor [Homo sapiens]
Length = 326
Score = 186 bits (473), Expect = 1e-46
Identities = 95/215 (44%), Positives = 129/215 (60%), Gaps = 9/215 (4%)
Query: 1067 PSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRW 1126
P +C + SG +TIYL RPL V CDM+TDGGGW VFQRR G +DF++ W
Sbjct: 115 PRNCKDLLDRGYFLSGWHTIYLPD--CRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDW 172
Query: 1127 RSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDL-QTANESAYAIYDFFQVASSKE 1185
+Y +GFG + EFWLG D +H LT E+RVDL +A Y F+VA E
Sbjct: 173 AAYKQGFGSQLGEFWLGNDNIHALT--AQGSSELRVDLVDFEGNHQFAKYKSFKVADEAE 230
Query: 1186 RYKLTVGKY-RGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNG 1244
+YKL +G + G+AG++LT HN F+T D+DND++ SNCA G WWY +CH +N NG
Sbjct: 231 KYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNG 290
Query: 1245 RY---GETKHSEGVNWEPWKGHEFSIPYVELKIRP 1276
Y ++ G+NW KG+++S E+K+RP
Sbjct: 291 LYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRP 325
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 182 bits (463), Expect = 1e-45
Identities = 184/728 (25%), Positives = 293/728 (40%), Gaps = 30/728 (4%)
Query: 359 VTDETENSLDVEWENPSTEVDYYKLRYGPMTG------QEVAEVTVPKSSDPKSRYDITG 412
+++ + SL V+W S V YK++Y P+TG E EV VP ++ + G
Sbjct: 240 LSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAG---ETSVRLRG 296
Query: 413 LHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDK 472
L P TEY++TV+ + G+ + RT + T + V+W V
Sbjct: 297 LRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGATGY 356
Query: 473 YVVRYTSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEID 532
V + G T++ + + S +L L+PG Y+V V G A T+
Sbjct: 357 RVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDAS 416
Query: 533 SPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRP 592
L + + +SW+ V + + ++V++ + + L GL+P
Sbjct: 417 VEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQP 476
Query: 593 GVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTD-RVTE---NMATVSWDPVQAAID 648
G EY + ++ E T PT + P + VTD + TE VSW PV A
Sbjct: 477 GTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGA-T 535
Query: 649 KYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDI 708
+Y + S G R + + Q++ L ++ G+ Y V V A+ G +E + + +
Sbjct: 536 QYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREP 595
Query: 709 DSPQNLVTDRVTENMAT---VSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLT 765
++P + RV + AT V+W PV + T + ++ +P + ++T +T
Sbjct: 596 ETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLP--PDSTATDIT 653
Query: 766 GLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLV-TDWVTENTATVSWDPVQATI 824
GL+PG Y V V +G +E A A+TD P V + ++ T++W V
Sbjct: 654 GLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGAT 713
Query: 825 DRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT- 883
Y V + SA+G + V E + L GL P EYTVHV A + A +T
Sbjct: 714 G-YRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTA 772
Query: 884 --EIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLT 941
+ L + ++ ++W V + S G R + S +
Sbjct: 773 PEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIR 832
Query: 942 GLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGG---ILTWTP-PS 997
GL G+ Y V V A G +E T + P L V Q G L W P P
Sbjct: 833 GLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPR 892
Query: 998 AQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTL 1057
AQ G++L +Q G + LG E + L GLE Y V L + T
Sbjct: 893 AQ--GFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTA 950
Query: 1058 STVGARFP 1065
T R P
Sbjct: 951 RTESPRVP 958
Score = 179 bits (453), Expect = 2e-44
Identities = 215/834 (25%), Positives = 344/834 (41%), Gaps = 53/834 (6%)
Query: 265 PQGLQLLKNTEDSLLVSWEPSS-QVDHYLLSYYPL---GKELSGK--QIQVPKEQHSYEI 318
P+ L L + + SL V W +S V Y + Y PL G+ L + ++ VP + S +
Sbjct: 235 PRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRL 294
Query: 319 LGLLPGTKYIVT-LRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN---- 373
GL P T+Y VT + N + + TT L + + T +SL V W +
Sbjct: 295 RGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEG-PELTIQNTTAHSLLVAWRSVPGA 353
Query: 374 PSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGK 433
V + L GP QE+ + + L PGT+Y++TV + G G
Sbjct: 354 TGYRVTWRVLSGGPTQQQEL--------GPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGP 405
Query: 434 PILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG--DTKEMAVHK 491
L RT+ + + + +SW+ V Y + + G +++ +
Sbjct: 406 ATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEA-RGYRLEWRRETGLEPPQKVVLPS 464
Query: 492 DESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTD-RVTE---NTA 547
D + L GL+PG Y++ ++ T T + P + VTD + TE
Sbjct: 465 DVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRV 524
Query: 548 TISWDPVQ-ATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGD 606
+SW PV AT + +VR T + R +++ Q++ L ++ G+ YTV V A+ G
Sbjct: 525 RVSWSPVPGATQYRIIVRSTQGVE---RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGP 581
Query: 607 RESKKADTNAPTDIDSPKNLVTDRVTENMAT---VSWDPVQAAIDKYVVRYTSAGGETRE 663
RE + + ++P + RV + AT V+W PV A + T +G E+ +
Sbjct: 582 REGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQ 641
Query: 664 VPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLV-TDRVTEN 722
+ + ++T +TGL+PG Y V V +G +E A A+TD P V + + +
Sbjct: 642 T-LPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSS 700
Query: 723 MATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKG 782
T++W V Y V + SA E ++ V E + L GL P EYTVHV A
Sbjct: 701 SVTITWTRVPGATG-YRVSWHSAHGPEKSQL-VSGEATVAELDGLEPDTEYTVHVRAHVA 758
Query: 783 AQESKKADTKAQT---DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR 839
+ A +T + L + + ++W V + S G R
Sbjct: 759 GVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRSEGGPMR 818
Query: 840 EVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVT-- 897
+ S + GL G+ Y+V V A G++E T + P L T V
Sbjct: 819 HQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQR 878
Query: 898 -ENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQ 956
E+ + W+PV +++ + G+ + +G E SS L GL P +Y V +
Sbjct: 879 GEHSLRLRWEPVPRA-QGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVL 937
Query: 957 KGAQESKKADTKAQTELD--PPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTV 1014
A E A+ A+TE P LR + L WTP S + YIL+++ G
Sbjct: 938 GPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVS-RASSYILSWRPLRGPG 996
Query: 1015 KEM-----QLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGAR 1063
+E+ L + GLE G +Y SL G R S T + V R
Sbjct: 997 QEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCPR 1050
Score = 157 bits (397), Expect = 6e-38
Identities = 165/649 (25%), Positives = 266/649 (40%), Gaps = 28/649 (4%)
Query: 432 GKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG-------DT 484
G P+ +P ++V + + V W + Y V+YT G +
Sbjct: 221 GVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSER 280
Query: 485 KEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQ-GSKKADTNALTEIDSPANLVTDRVT 543
+E+ V E+S L GL+P Y+V V A N G + T T ++ P L T
Sbjct: 281 QEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQNTT 339
Query: 544 ENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQ 603
++ ++W V Y V + T++ +G Q S +L L PG +Y V V
Sbjct: 340 AHSLLVAWRSVPGATG-YRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTL 398
Query: 604 KGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGE-TR 662
G A TD + L + +SW+ V A + G E +
Sbjct: 399 FGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQ 458
Query: 663 EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTD-RVTE 721
+V + + + L GL+PG EY + ++ E T T + P + VTD + TE
Sbjct: 459 KVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATE 518
Query: 722 ---NMATVSWDPV-RATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHV 777
VSW PV AT R +VR T G R + + Q++ L ++ G+ YTV V
Sbjct: 519 LPGQRVRVSWSPVPGATQYRIIVRST---QGVERTLVLPGSQTAFDLDDVQAGLSYTVRV 575
Query: 778 WAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTAT---VSWDPVQATIDRYVVHYTSA 834
A+ G +E + + + ++P + V + AT V+W PV + + +++
Sbjct: 576 SARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA-SGFRISWSTG 634
Query: 835 NGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLV-T 893
+G + + ++T +TGL+PG Y V V +G +E A A+T+ GP V
Sbjct: 635 SGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHV 694
Query: 894 DWVTENMATVSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTVLTGLRPGMEYMVHV 953
+ + T++W V Y V + SA G + V E + L GL P EY VHV
Sbjct: 695 TQASSSSVTITWTRVPGATG-YRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHV 753
Query: 954 WAQKGAQESKKADTKAQTELDP-PRNLRPSAVTQSGGIL--TWTPPSAQIHGYILTYQFP 1010
A + A +T +P R R + S +L TW + + +
Sbjct: 754 RAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRSE 813
Query: 1011 DGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLST 1059
G ++ L ++GLE G +Y V + A G R VS ++T
Sbjct: 814 GGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTT 862
Score = 139 bits (349), Expect = 2e-32
Identities = 145/569 (25%), Positives = 225/569 (39%), Gaps = 23/569 (4%)
Query: 533 SPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADD------QETREVLVGKEQSSTV 586
+P +LV + + + W + Y V+YT E +EV V ++S
Sbjct: 234 APRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVR 293
Query: 587 LTGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA 646
L GLRP EY V V A + + A T L T + V+W V A
Sbjct: 294 LRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGA 353
Query: 647 IDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT 706
V +GG T++ +G Q S +L L PG +Y V V G A+T
Sbjct: 354 TGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMART 413
Query: 707 DIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTG 766
D Q L + +SW+ V + ++V + + + L G
Sbjct: 414 DASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDG 473
Query: 767 LRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLVTD-WVTE---NTATVSWDPVQA 822
L+PG EY + ++ E T T + P + VTD TE VSW PV
Sbjct: 474 LQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPG 533
Query: 823 TIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQ 882
+Y + S G R + + Q++ L ++ G+ YTV V A+ G +E + +
Sbjct: 534 A-TQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVR 592
Query: 883 TEIDGPKNLVTDWVTENMAT---VSWDPVQATIDKYMVRYTSADGETREVPVGKEHSSTV 939
E + P + V + AT V+W PV + + +++ G + + ++T
Sbjct: 593 REPETPLAVPGLRVVVSDATRVRVAWGPVPGA-SGFRISWSTGSGPESSQTLPPDSTATD 651
Query: 940 LTGLRPGMEYMVHVWAQKGAQESKKADTKAQTE-LDPPRNLRPSAVTQSGGILTWT-PPS 997
+TGL+PG Y V V +G +E A A+T+ L P R + + + S +TWT P
Sbjct: 652 ITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPG 711
Query: 998 AQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTL 1057
A GY +++ G K + E L GLE Y V + A G S +
Sbjct: 712 AT--GYRVSWHSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVV 769
Query: 1058 STVGARFPHPSDCSQVQQNSNAASGLYTI 1086
T P P Q NA+S + I
Sbjct: 770 RTA----PEPVGRVSRLQILNASSDVLRI 794
Score = 50.4 bits (119), Expect = 1e-05
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 6/152 (3%)
Query: 268 LQLLKNTEDSLLVSWEPSSQVDHYLLSYYPL---GKELSGKQIQVPKEQHSYEILGLLPG 324
L+++ + DS+ ++W P S+ Y+LS+ PL G+E+ G +P S + GL PG
Sbjct: 962 LRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPG 1021
Query: 325 TKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTE--VDYYK 382
YI +L V + V P+ + T + G A V + D +T ++
Sbjct: 1022 VSYIFSLTPVLDGV-RGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLV 1080
Query: 383 LRYGPMTGQEVAEVTVPKSSDPKSRYDITGLH 414
L GP+ Q V + S P + + G H
Sbjct: 1081 LALGPLGPQAVQVGLLSYSHRPSPLFPLNGSH 1112
>gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]
Length = 255
Score = 181 bits (458), Expect = 5e-45
Identities = 93/219 (42%), Positives = 129/219 (58%), Gaps = 13/219 (5%)
Query: 1067 PSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRW 1126
P DC + + G+Y IY G S P+ V+CDM T+GG W VFQ+R G + FF+ W
Sbjct: 38 PLDCDDIYAQGYQSDGVYLIYPSGP-SVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGW 96
Query: 1127 RSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQT-ANESAYAIYDFFQ-----V 1180
Y GFG E+WLGL +H LT +YE+RVDL+ N +AYA Y F V
Sbjct: 97 NDYKLGFGRADGEYWLGLQNMHLLTL--KQKYELRVDLEDFENNTAYAKYADFSISPNAV 154
Query: 1181 ASSKERYKLTVGKYR-GTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHL 1239
++ ++ Y L V + G AGD+L+YH+G KF+TFDRD D+ + NCA G +W+++CH
Sbjct: 155 SAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHF 214
Query: 1240 ANPNGRY---GETKHSEGVNWEPWKGHEFSIPYVELKIR 1275
AN NG Y ++ G+NW WKG +S+ E+KIR
Sbjct: 215 ANLNGFYLGGSHLSYANGINWAQWKGFYYSLKRTEMKIR 253
>gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]
Length = 288
Score = 178 bits (451), Expect = 3e-44
Identities = 87/203 (42%), Positives = 125/203 (61%), Gaps = 9/203 (4%)
Query: 1065 PHPSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFK 1124
P P +C ++ SG Y + L R L V+CDM+T+GGGW+VFQRR G +DFF+
Sbjct: 77 PGPRNCRELLSQGATLSGWYHLCL--PEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFR 134
Query: 1125 RWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQTAN-ESAYAIYDFFQVASS 1183
W SY GFG+ EFWLG + LH LT +E+RV+L+ N +A Y F++
Sbjct: 135 SWSSYRAGFGNQESEFWLGNENLHQLT--LQGNWELRVELEDFNGNRTFAHYATFRLLGE 192
Query: 1184 KERYKLTVGKY-RGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANP 1242
+ Y+L +GK+ GTAGD+L+ H+G FTT+D D+D + SNCA+ HG WWY +C+ +N
Sbjct: 193 VDHYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNL 252
Query: 1243 NGRYGETK---HSEGVNWEPWKG 1262
NGRY ++ H G++W +G
Sbjct: 253 NGRYAVSEAAAHKYGIDWASGRG 275
>gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens]
Length = 299
Score = 176 bits (446), Expect = 1e-43
Identities = 86/201 (42%), Positives = 124/201 (61%), Gaps = 9/201 (4%)
Query: 1067 PSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRW 1126
P +C ++ SG Y + L R L V+CDM+T+GGGW+VFQRR G +DFF+ W
Sbjct: 90 PRNCRELLSQGATLSGWYHLCL--PEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSW 147
Query: 1127 RSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQTAN-ESAYAIYDFFQVASSKE 1185
SY GFG+ EFWLG + LH LT +E+RV+L+ N +A Y F++ +
Sbjct: 148 SSYRAGFGNQESEFWLGNENLHQLT--LQGNWELRVELEDFNGNRTFAHYATFRLLGEVD 205
Query: 1186 RYKLTVGKY-RGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNG 1244
Y+L +GK+ GTAGD+L+ H+G FTT+D D+D + SNCA+ HG WWY +C+ +N NG
Sbjct: 206 HYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNG 265
Query: 1245 RYGETK---HSEGVNWEPWKG 1262
RY ++ H G++W +G
Sbjct: 266 RYAVSEAAAHKYGIDWASGRG 286
>gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]
Length = 491
Score = 171 bits (433), Expect = 4e-42
Identities = 78/214 (36%), Positives = 132/214 (61%), Gaps = 9/214 (4%)
Query: 1069 DCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRS 1128
DC Q ++ ++ SG+Y I +++ P+Q++C+ D GGW V Q+R G ++FF+ W +
Sbjct: 279 DCQQAKEAGHSVSGIYMIKPE-NSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWEN 337
Query: 1129 YVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQT-ANESAYAIYDFFQVASSKERY 1187
Y +GFG+ E+WLGL+ ++ L+ Y++ ++L+ +++ YA Y F++ E Y
Sbjct: 338 YKKGFGNIDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYSSFRLEPESEFY 395
Query: 1188 KLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPN---- 1243
+L +G Y+G AGD++ +HNG +FTT DRD D+ NCA H GGWWY C +N N
Sbjct: 396 RLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWY 455
Query: 1244 -GRYGETKHSEGVNWEPWKGHEFSIPYVELKIRP 1276
G + +KH +G+ W ++G +S+ V++ I+P
Sbjct: 456 RGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKP 489
>gi|10863949 angiopoietin-like 7 [Homo sapiens]
Length = 346
Score = 168 bits (425), Expect = 4e-41
Identities = 88/217 (40%), Positives = 121/217 (55%), Gaps = 8/217 (3%)
Query: 1069 DCSQVQQNSNAASGLYTIYLHGDASRP-LQVYCDMETDGGGWIVFQRRNTGQLDFFKRWR 1127
DCS + Q + SG+Y + P L+V+CDMET GGGW + QRR +G + F++ W+
Sbjct: 130 DCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYRDWK 189
Query: 1128 SYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQTANESAYAIYDFFQVASSKERY 1187
Y +GFG +FWLG + +H L+ P R V ++ N YA Y F + + Y
Sbjct: 190 QYKQGFGSIRGDFWLGNEHIHRLSR-QPTRLRVEMEDWEGN-LRYAEYSHFVLGNELNSY 247
Query: 1188 KLTVGKYRGTAG-DALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNG-- 1244
+L +G Y G G DAL YHN F+T D+DND L CA GG+WY C +N NG
Sbjct: 248 RLFLGNYTGNVGNDALQYHNNTAFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVY 307
Query: 1245 -RYGE-TKHSEGVNWEPWKGHEFSIPYVELKIRPHGY 1279
R GE KH +G+ W W G +S+ VE+KIRP +
Sbjct: 308 YRLGEHNKHLDGITWYGWHGSTYSLKRVEMKIRPEDF 344
>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
Length = 493
Score = 165 bits (418), Expect = 2e-40
Identities = 84/232 (36%), Positives = 134/232 (57%), Gaps = 13/232 (5%)
Query: 1056 TLSTVGARFPHPS----DCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIV 1111
TL+++ + PS DC Q ++ + S +Y + + +R +QV+CD D GGW V
Sbjct: 260 TLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPE-NTNRLMQVWCDQRHDPGGWTV 318
Query: 1112 FQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQT-ANES 1170
QRR G ++FF+ W +Y +GFG+ E+WLGL+ ++ LT Y++ V ++ +
Sbjct: 319 IQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTN--QGNYKLLVTMEDWSGRK 376
Query: 1171 AYAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHG 1230
+A Y F++ E YKL +G+Y G AGD+ T+HNG +FTT DRD+D+ NCA G
Sbjct: 377 VFAEYASFRLEPESEYYKLRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKG 436
Query: 1231 GWWYKNCHLANPN-----GRYGETKHSEGVNWEPWKGHEFSIPYVELKIRPH 1277
GWWY C +N N G + +++ +GV W ++G +S+ V + IRP+
Sbjct: 437 GWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPN 488
>gi|7705276 angiopoietin 4 [Homo sapiens]
Length = 503
Score = 163 bits (412), Expect = 1e-39
Identities = 84/215 (39%), Positives = 127/215 (59%), Gaps = 11/215 (5%)
Query: 1069 DCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRS 1128
DC+++Q++ +ASG+YTI + +A++P +V+CD+++ GG W + QRR G ++F + W+
Sbjct: 290 DCAEIQRSGASASGVYTIQV-SNATKPRKVFCDLQSSGGRWTLIQRRENGTVNFQRNWKD 348
Query: 1129 YVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQT-ANESAYAIYDFFQVASSKERY 1187
Y +GFGDP E WLG + +H LT A Y +RV+LQ AYA Y+ F + S + Y
Sbjct: 349 YKQGFGDPAGEHWLGNEVVHQLT--RRAAYSLRVELQDWEGHEAYAQYEHFHLGSENQLY 406
Query: 1188 KLTVGKYRGTAG--DALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGR 1245
+L+V Y G+AG +L N F+T D DND L CA GGWW+ C L+N NG
Sbjct: 407 RLSVVGYSGSAGRQSSLVLQN-TSFSTLDSDNDHCLCKCAQVMSGGWWFDACGLSNLNGV 465
Query: 1246 YGETKHS----EGVNWEPWKGHEFSIPYVELKIRP 1276
Y + +G+ W +KG +S+ + IRP
Sbjct: 466 YYHAPDNKYKMDGIRWHYFKGPSYSLRASRMMIRP 500
>gi|70906435 fibrinogen, beta chain preproprotein [Homo sapiens]
Length = 491
Score = 157 bits (398), Expect = 5e-38
Identities = 96/265 (36%), Positives = 132/265 (49%), Gaps = 47/265 (17%)
Query: 1056 TLSTVGARFPHPS--DCSQVQQNSNAASGLYTIYLHGDAS-RPLQVYCDMETDGGGWIVF 1112
T TV P S +C ++ + S +Y I D+S +P +VYCDM T+ GGW V
Sbjct: 225 TPCTVSCNIPVVSGKECEEIIRKGGETSEMYLI--QPDSSVKPYRVYCDMNTENGGWTVI 282
Query: 1113 QRRNTGQLDFFKRWRSYVEGFGDPMK------------EFWLGLDKLHNLTTGTPARYEV 1160
Q R G +DF ++W Y +GFG+ E+WLG DK+ LT P +
Sbjct: 283 QNRQDGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMGPTELLI 342
Query: 1161 RVDLQTANESAYAIYDFFQVASSKERYKLTVGKYRGTAGDAL--------------TYHN 1206
++ + A Y F V + +Y+++V KYRGTAG+AL T HN
Sbjct: 343 EME-DWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDGASQLMGENRTMTIHN 401
Query: 1207 GWKFTTFDRDNDIALSN-----CALTHHGGWWYKNCHLANPNGRY--------GETKH-- 1251
G F+T+DRDND L++ C+ GGWWY CH ANPNGRY KH
Sbjct: 402 GMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNRCHAANPNGRYYWGGQYTWDMAKHGT 461
Query: 1252 SEGVNWEPWKGHEFSIPYVELKIRP 1276
+GV W WKG +S+ + +KIRP
Sbjct: 462 DDGVVWMNWKGSWYSMRKMSMKIRP 486
>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
preproprotein [Homo sapiens]
Length = 866
Score = 156 bits (394), Expect = 1e-37
Identities = 99/237 (41%), Positives = 124/237 (52%), Gaps = 34/237 (14%)
Query: 1069 DCSQVQQN--SNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRW 1126
DC V Q S SG++ I L G +S+ VYCD ET GGW++ Q+R G L+F + W
Sbjct: 631 DCDDVLQTHPSGTQSGIFNIKLPG-SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTW 689
Query: 1127 RSYVEGFG----DPMKEFWLGLDKLHNLTTGTPARYEVRVDLQT-ANESAYAIYDFFQVA 1181
+ Y GFG + EFWLG D LH LT +RV+L+ A AYA Y F +V
Sbjct: 690 QDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSV---LRVELEDWAGNEAYAEYHF-RVG 745
Query: 1182 SSKERYKLTVGKYRGTAGDAL-----------TYHNGWKFTTFDRDNDIALSNCALTHHG 1230
S E Y L V Y GTAGDAL T HN +F+TFDRD D NCA + G
Sbjct: 746 SEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGG 805
Query: 1231 GWWYKNCHLAN------PNGRYGETKHS-----EGVNWEPWKGHEFSIPYVELKIRP 1276
GWWY NC AN P G Y +S GV W ++G ++S+ V +KIRP
Sbjct: 806 GWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRP 862
>gi|29893555 angiopoietin-like 6 [Homo sapiens]
Length = 470
Score = 155 bits (392), Expect = 2e-37
Identities = 78/214 (36%), Positives = 121/214 (56%), Gaps = 11/214 (5%)
Query: 1069 DCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIVFQRRNTGQLDFFKRWRS 1128
DC++ +Q + SG+Y + + + V+C+ + +GGGW V QRR G ++FF W+
Sbjct: 259 DCAEARQAGHEQSGVYELRV---GRHVVSVWCEQQLEGGGWTVIQRRQDGSVNFFTTWQH 315
Query: 1129 YVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQT-ANESAYAIYDFFQVASSKERY 1187
Y GFG P E+WLGL+ ++ LT+ +E+ V L+ A A YD F + + Y
Sbjct: 316 YKAGFGRPDGEYWLGLEPVYQLTSR--GDHELLVLLEDWGGRGARAHYDGFSLEPESDHY 373
Query: 1188 KLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPN---- 1243
+L +G+Y G AGD+L++HN F+T DRD D NCAL GGWWY C +N N
Sbjct: 374 RLRLGQYHGDAGDSLSWHNDKPFSTVDRDRDSYSGNCALYQRGGWWYHACAHSNLNGVWH 433
Query: 1244 -GRYGETKHSEGVNWEPWKGHEFSIPYVELKIRP 1276
G + +++ +GV W ++G +S+ + IRP
Sbjct: 434 HGGHYRSRYQDGVYWAEFRGGAYSLRKAAMLIRP 467
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,726,331
Number of Sequences: 37866
Number of extensions: 2562095
Number of successful extensions: 11118
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 356
Number of HSP's that attempted gapping in prelim test: 5148
Number of HSP's gapped (non-prelim): 2680
length of query: 1299
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1185
effective length of database: 13,930,794
effective search space: 16507990890
effective search space used: 16507990890
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.