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Search of human proteins with 62865876
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62865876 immunoglobulin superfamily, member 11 isoform b
[Homo sapiens]
(431 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 865 0.0
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 833 0.0
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 179 4e-45
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 145 7e-35
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 135 9e-32
gi|148664205 endothelial cell adhesion molecule [Homo sapiens] 125 7e-29
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] 124 1e-28
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 123 3e-28
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s... 87 2e-17
gi|8393638 F11 receptor precursor [Homo sapiens] 73 4e-13
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 70 5e-12
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] 64 3e-10
gi|7657359 contactin 5 isoform long [Homo sapiens] 63 5e-10
gi|28373129 contactin 5 isoform short [Homo sapiens] 63 5e-10
gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens] 62 1e-09
gi|118572606 hemicentin 1 [Homo sapiens] 61 2e-09
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 61 2e-09
gi|19743806 roundabout 1 isoform b [Homo sapiens] 60 3e-09
gi|67188443 CD276 antigen isoform a [Homo sapiens] 60 3e-09
gi|4506569 roundabout 1 isoform a [Homo sapiens] 60 3e-09
gi|224994173 roundabout 1 isoform d [Homo sapiens] 60 4e-09
gi|224994171 roundabout 1 isoform c [Homo sapiens] 60 4e-09
gi|13376852 CD276 antigen isoform b [Homo sapiens] 60 4e-09
gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo ... 60 4e-09
gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo ... 60 4e-09
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 59 1e-08
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 59 1e-08
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 58 1e-08
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 58 1e-08
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 57 3e-08
>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
sapiens]
Length = 431
Score = 865 bits (2234), Expect = 0.0
Identities = 431/431 (100%), Positives = 431/431 (100%)
Query: 1 MTSQRSPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWM 60
MTSQRSPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWM
Sbjct: 1 MTSQRSPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWM 60
Query: 61 VTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQC 120
VTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQC
Sbjct: 61 VTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQC 120
Query: 121 LVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEK 180
LVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEK
Sbjct: 121 LVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEK 180
Query: 181 LDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNI 240
LDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNI
Sbjct: 181 LDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNI 240
Query: 241 GLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFH 300
GLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFH
Sbjct: 241 GLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFH 300
Query: 301 TEISSSDNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYAN 360
TEISSSDNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYAN
Sbjct: 301 TEISSSDNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYAN 360
Query: 361 GTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVM 420
GTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVM
Sbjct: 361 GTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVM 420
Query: 421 VPAQSRAGSLV 431
VPAQSRAGSLV
Sbjct: 421 VPAQSRAGSLV 431
>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
sapiens]
Length = 430
Score = 833 bits (2152), Expect = 0.0
Identities = 414/414 (100%), Positives = 414/414 (100%)
Query: 18 GVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQ 77
GVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQ
Sbjct: 17 GVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQ 76
Query: 78 GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTG 137
GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTG
Sbjct: 77 GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTG 136
Query: 138 LTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ 197
LTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ
Sbjct: 137 LTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ 196
Query: 198 GTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFC 257
GTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFC
Sbjct: 197 GTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFC 256
Query: 258 IALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSDNNTLTSSNAY 317
IALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSDNNTLTSSNAY
Sbjct: 257 IALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSDNNTLTSSNAY 316
Query: 318 NSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGTHLVPGQHKTLVVTAN 377
NSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGTHLVPGQHKTLVVTAN
Sbjct: 317 NSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGTHLVPGQHKTLVVTAN 376
Query: 378 RGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVMVPAQSRAGSLV 431
RGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVMVPAQSRAGSLV
Sbjct: 377 RGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLERIGAVPVMVPAQSRAGSLV 430
>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
sapiens]
Length = 365
Score = 179 bits (454), Expect = 4e-45
Identities = 122/366 (33%), Positives = 187/366 (51%), Gaps = 19/366 (5%)
Query: 11 LLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALIN-LNVIWMVTPLSNANQ 69
+LL + A SL ++ I+ A+G+ A LPC FT S L++ W+++P N
Sbjct: 8 VLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKV 67
Query: 70 PEQVILYQGGQMFDGA-PRFHGRVGFTGT-MPATNVSIFINNTQLSDTGTYQCLVNNLPD 127
+ +ILY G +++D P GRV FT + + + SI + N QLSD GTYQC V P
Sbjct: 68 DQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPG 127
Query: 128 IGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKL 187
+ + I L VLV PS C + GS++IGSD + C +EG Y W+KL ++ K+
Sbjct: 128 VANKKIH---LVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKM 184
Query: 188 PPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAI 247
P + + ++++N S+ SG Y C N +G+ CLL L V+ P GLIAGAI
Sbjct: 185 PTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPS-NKAGLIAGAI 243
Query: 248 GTGAVIIIFCIALILGAFFYWRSKNKEEE-EEEIPNEIREDDLPPKCSSAKAFHTEISSS 306
G ++ + I LI+ F R K +EE+ E+E+ ++IRED PPK ++ A S
Sbjct: 244 -IGTLLALALIGLII---FCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTA--RSYIGS 297
Query: 307 DNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGT--HL 364
++++L S + N +S K N F QS + P++ G +
Sbjct: 298 NHSSLGSMSPSNMEGYS---KTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVM 354
Query: 365 VPGQHK 370
+P Q K
Sbjct: 355 IPAQSK 360
>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
sapiens]
Length = 327
Score = 145 bits (366), Expect = 7e-35
Identities = 103/318 (32%), Positives = 155/318 (48%), Gaps = 20/318 (6%)
Query: 9 APLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIW-MVTPLSNA 67
A L L L G+A ++V P S + G+ A L CT++TS + + W V P
Sbjct: 12 ALLGFLCLSGLAVEVKVPTEPLSTPL--GKTAELTCTYSTSVG-DSFALEWSFVQPGKPI 68
Query: 68 NQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIF-INNTQLSDTGTYQCLVNNLP 126
++ ++ + G ++ + RV P V+ + + SDTGTY C VNN P
Sbjct: 69 SESHPILYFTNGHLYPTGSKSK-RVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNPP 127
Query: 127 DIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDN-TL 185
D +G+ LTVLVPPS P C G +G L CSS EG P+P Y W +L
Sbjct: 128 DFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRLGTFPT 187
Query: 186 KLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAG 245
P + QD+V G + + N+S SSG Y+CVA+N +G+++C L L V P G +AG
Sbjct: 188 PSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQ---GRVAG 244
Query: 246 A-IGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPP--------KCSSA 296
A IG +++ +A F + + K+ +E +++RED + P + S+
Sbjct: 245 ALIGVLLGVLLLSVAAFCLVRFQ-KERGKKPKETYGGSDLREDAIAPGISEHTCMRADSS 303
Query: 297 KAFHTEISSSDNNTLTSS 314
K F SS+ T T S
Sbjct: 304 KGFLERPSSASTVTTTKS 321
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 135 bits (339), Expect = 9e-32
Identities = 91/282 (32%), Positives = 136/282 (48%), Gaps = 22/282 (7%)
Query: 11 LLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTS-AALINLNVIWMVTPLSNANQ 69
L+L L G + ++V+ G + V G L C +TT+ A+ L++ W +
Sbjct: 10 LILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEM-E 68
Query: 70 PEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIG 129
P + QGGQ +F R+ TG+ N SI I++ Q +D+G Y C VNN PD
Sbjct: 69 PISIYFSQGGQAV-AIGQFKDRI--TGSNDPGNASITISHMQPADSGIYICDVNNPPDFL 125
Query: 130 GRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPP 189
G+N G+ ++VLV PS P C +QG + G + L C S G P P Y W KL+ +P
Sbjct: 126 GQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPV 185
Query: 190 TATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGA--- 246
+ G + I N++ G YQC A N +G S+C +DL P+ +G+I GA
Sbjct: 186 KENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPE---VGIIVGALIG 242
Query: 247 --IGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIRE 286
+G +I + C A R+K K + +E I E
Sbjct: 243 SLVGAAIIISVVCFA---------RNKAKAKAKERNSKTIAE 275
>gi|148664205 endothelial cell adhesion molecule [Homo sapiens]
Length = 390
Score = 125 bits (314), Expect = 7e-29
Identities = 117/438 (26%), Positives = 188/438 (42%), Gaps = 73/438 (16%)
Query: 8 LAPLLLLSLHGVA----ASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLN------V 57
L L L L +A A L++ +Q G VLP +T + + V
Sbjct: 12 LLRFLFLGLSALAPPSRAQLQLHLPANRLQAVEGGEVVLPAWYTLHGEVSSSQPWEVPFV 71
Query: 58 IWMVTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGT 117
+W + +QV+ Y +G V +MP+ N+S+ + Q D+G
Sbjct: 72 MWF---FKQKEKEDQVLSY-----INGVTTSKPGVSLVYSMPSRNLSLRLEGLQEKDSGP 123
Query: 118 YQCLVNNLPDIG---GRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRP 174
Y C VN G G +I L VLVPP+ P C++QG +G++V L C S P
Sbjct: 124 YSCSVNVQDKQGKSRGHSIKTLELNVLVPPAPPSCRLQGVPHVGANVTLSCQSPRSKPAV 183
Query: 175 TYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVIS 234
Y W++ + + D ++G++++ N+S+ +G+Y C A N +GT+ C + L+V S
Sbjct: 184 QYQWDRQLPSFQTFFAPALDVIRGSLSLTNLSSSMAGVYVCKAHNEVGTAQCNVTLEV-S 242
Query: 235 PQPRNIGLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCS 294
P ++AGA+ V + + L+ G + + K EE N+I+ED + P+
Sbjct: 243 TGP-GAAVVAGAV----VGTLVGLGLLAGLVLLYHRRGKALEEP--ANDIKEDAIAPRTL 295
Query: 295 S-AKAFHTEISSSDNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQSFSFHSGNAN 353
K+ T + +++TS+ A + P T S+S
Sbjct: 296 PWPKSSDTISKNGTLSSVTSARALRPPHGPPRPGALTPTPSLS----------------- 338
Query: 354 IPSIYANGTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRKPRPPHTHSYTISHATLER 413
+ +P + G+ PQ +S G V S + L R
Sbjct: 339 --------SQALPSPR----LPTTDGAHPQPISPIPGGV--------------SSSGLSR 372
Query: 414 IGAVPVMVPAQSRAGSLV 431
+GAVPVMVPAQS+AGSLV
Sbjct: 373 MGAVPVMVPAQSQAGSLV 390
>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
Length = 373
Score = 124 bits (312), Expect = 1e-28
Identities = 116/384 (30%), Positives = 166/384 (43%), Gaps = 72/384 (18%)
Query: 55 LNVIWMVTPLSNANQPEQVILYQGGQMFDGAPRFH-GRVGFTGTMPATNVSIFINNTQLS 113
L++ W++T N + VI Y +++ GRV F A + S+ I + S
Sbjct: 47 LDIEWLLT--DNEGNQKVVITYSSRHVYNNLTEEQKGRVAFASNFLAGDASLQIEPLKPS 104
Query: 114 DTGTYQCLVNNLPDIGGRNI-GVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIP 172
D G Y C V N GR + L VLV PS P C+++G GSD+ L C S G
Sbjct: 105 DEGRYTCKVKN----SGRYVWSHVILKVLVRPSKPKCELEGELTEGSDLTLQCESSSGTE 160
Query: 173 RPTYLW----EKLDNTLKLPPTATQD-QVQGTVTIRNISALSSGLYQCVASNAIGTSTCL 227
Y W EK +LPP + D G V ++N++ SGLYQC A N G +C+
Sbjct: 161 PIVYYWQRIREKEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAGNEAGKESCV 220
Query: 228 LDLQVISPQPRNIGLIAGA---IGTGAVIIIFCIALILGAFFYWRSKNKEE-EEEEIPNE 283
+ + V Q +IG++AGA I GA++I + L++ R K+KE EEEE PNE
Sbjct: 221 VRVTVQYVQ--SIGMVAGAVTGIVAGALLIFLLVWLLI------RRKDKERYEEEERPNE 272
Query: 284 IREDDLPPKCSSAKAFHTEISSSDNNTLTSSNAYNSRYWSNNPKVHRNTESVSHFSDLGQ 343
IRED PK K SSS + + S + ++R +N+ + T S G
Sbjct: 273 IREDAEAPKARLVK----PSSSSSGSRSSRSGSSSTRSTANSASRSQRTLSTDAAPQPGL 328
Query: 344 SFSFHSGNANIPSIYANGTHLVPGQHKTLVVTANRGSSPQVMSRSNGSVSRKPRPPHTHS 403
+ +S LV RGS P+
Sbjct: 329 ATQAYS----------------------LVGPEVRGSEPK-------------------- 346
Query: 404 YTISHATLERIGAVPVMVPAQSRA 427
+ HA L + P M+P+QSRA
Sbjct: 347 -KVHHANLTKAETTPSMIPSQSRA 369
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 123 bits (309), Expect = 3e-28
Identities = 85/275 (30%), Positives = 135/275 (49%), Gaps = 16/275 (5%)
Query: 22 SLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQM 81
++ V ++ ++G+ LPCT+ TS + + W L++ E+V+++
Sbjct: 21 AISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLTHT---ERVVIWP---- 73
Query: 82 FDGAPRFHG-----RVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVT 136
F HG RV + ++ SI I+ ++D GTY+C V+ + D+ G
Sbjct: 74 FSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRV 133
Query: 137 GLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQV 196
L VLVPPS P C I+G IG+++ L C S+EG P P Y W++ N L Q
Sbjct: 134 RLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRY-NILNQEQPLAQPAS 192
Query: 197 QGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAG-AIGTGAVIII 255
V+++NIS +SG Y C +SN GT C + + V SP N+ L G A+G A +II
Sbjct: 193 GQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPS-MNVALYVGIAVGVVAALII 251
Query: 256 FCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLP 290
I +I + N E++E+ PN ++ P
Sbjct: 252 IGI-IIYCCCCRGKDDNTEDKEDARPNREAYEEPP 285
>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
sapiens]
Length = 414
Score = 87.4 bits (215), Expect = 2e-17
Identities = 75/285 (26%), Positives = 123/285 (43%), Gaps = 50/285 (17%)
Query: 55 LNVIWMVTPLSNANQPEQVIL-YQGGQMFDGA-PRFHGRVGFTGTMPAT-NVSIFINNTQ 111
L++ WM A+ E V L YQ ++ G+ P RV F + P+ + SI + N Q
Sbjct: 58 LDIEWMQVNSDPAHHRENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQ 117
Query: 112 LSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGI 171
+SDT TY+C V + I +TV P+ P C +G G+DV+L C + G
Sbjct: 118 VSDTATYECRVKKTTMATRKVI----VTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGS 173
Query: 172 PRPTYLWEKLDN----------------------TLKLPPTATQDQVQGTVTIRNISALS 209
+Y W K+ + Q G + +++IS
Sbjct: 174 QPLSYKWAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRAD 233
Query: 210 SGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALIL------- 262
GLYQC +N +G S C+++++V R IG+I G + G+++ + C+A+ +
Sbjct: 234 DGLYQCTVANNVGYSVCVVEVKV--SDSRRIGVIIGIV-LGSLLALGCLAVGIWGLVCCC 290
Query: 263 ----------GAFFYWRSKNKEEEE-EEIPNEIREDDLPPKCSSA 296
GAF Y ++ +EIRED + P C ++
Sbjct: 291 CGGSGAGGARGAFGYGNGGGVGGGACGDLASEIREDAVAPGCKAS 335
>gi|8393638 F11 receptor precursor [Homo sapiens]
Length = 299
Score = 73.2 bits (178), Expect = 4e-13
Identities = 70/267 (26%), Positives = 110/267 (41%), Gaps = 37/267 (13%)
Query: 11 LLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQP 70
+LL SL S+ V S +++ P L C ++ + V W +
Sbjct: 19 ILLCSL--ALGSVTVHSSEPEVRIPENNPVKLSCAYS---GFSSPRVEWKF----DQGDT 69
Query: 71 EQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGG 130
+++ Y + RV F T I + DTGTY C+V+ + GG
Sbjct: 70 TRLVCYNNKI----TASYEDRVTFLPT------GITFKSVTREDTGTYTCMVS---EEGG 116
Query: 131 RNIGVTG--LTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLP 188
+ G L VLVPPS P I S IG+ +L CS ++G P Y W K +
Sbjct: 117 NSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFKDGIVMPTN 176
Query: 189 PTATQ---------DQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRN 239
P +T+ + G + +SA +G Y C A N GT +++ + + RN
Sbjct: 177 PKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRMEAVE-RN 235
Query: 240 IGLIAGAIGTGAVIIIFCIALILGAFF 266
+G+I A+ V +I L+ G +F
Sbjct: 236 VGVIVAAV---LVTLILLGILVFGIWF 259
>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
Length = 298
Score = 69.7 bits (169), Expect = 5e-12
Identities = 52/165 (31%), Positives = 76/165 (46%), Gaps = 14/165 (8%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNI--GVTGLTVLVPPSAPHCQIQGSQDIGSDV 161
+I I N SD G Y+C V+ P G+N+ L VLV P+ P C++ S G+ V
Sbjct: 93 NIRIKNVTRSDAGKYRCEVS-APSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVV 151
Query: 162 ILLCSSEEGIPRPTYLWEK-----LDN----TLKLPPTATQDQVQGTVTIRNISALSSGL 212
L C +EG P P Y W K L+N + + T + GT+ +S L +G
Sbjct: 152 ELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGE 211
Query: 213 YQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFC 257
Y C A N++G C + + NI I A+ A++I C
Sbjct: 212 YSCEARNSVGYRRC--PGKRMQVDDLNISGIIAAVVVVALVISVC 254
>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
Length = 355
Score = 63.5 bits (153), Expect = 3e-10
Identities = 57/197 (28%), Positives = 84/197 (42%), Gaps = 19/197 (9%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
S+ I N D+ Y+C V D + V LTV V P P C++ + +G L
Sbjct: 144 SLKIWNVTRRDSALYRCEVVARNDRKEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATL 203
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQ---------DQVQGTVTIRNISALSSGLYQ 214
C EG PRP Y W + D L A + GT+ + SG Y
Sbjct: 204 HCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYY 263
Query: 215 CVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALI-LGAFFYWRSK-- 271
C+ASN G++ C + Q + NIG I G G ++++ +ALI LG +R
Sbjct: 264 CIASNDAGSARC--EEQEMEVYDLNIGGIIG----GVLVVLAVLALITLGICCAYRRGYF 317
Query: 272 -NKEEEEEEIPNEIRED 287
N +++ E N + D
Sbjct: 318 INNKQDGESYKNPGKPD 334
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 63.2 bits (152), Expect = 5e-10
Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I N QL D G Y+C N G+N L V P D GS + C
Sbjct: 356 IPNVQLDDAGIYECRAENSR---GKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECK 412
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
+ G PRPTY W L N + L P + + V G + I N++ +G+YQC+A N G
Sbjct: 413 AT-GKPRPTYRW--LKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYA 469
Query: 227 LLDLQVISPQP 237
+L++++ P
Sbjct: 470 SAELKILASAP 480
Score = 53.1 bits (126), Expect = 5e-07
Identities = 49/184 (26%), Positives = 76/184 (41%), Gaps = 11/184 (5%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLV-PPSAPHCQIQGSQDIGSD 160
N + I+N SD G YQCL N G L +L P+ Q++ + + D
Sbjct: 440 NGVLMIHNVNQSDAGMYQCLAENK---YGAIYASAELKILASAPTFALNQLKKTIIVTKD 496
Query: 161 --VILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVAS 218
V++ C +G P+PT W+K D ++ G++ I N S G Y C
Sbjct: 497 QEVVIEC-KPQGSPKPTISWKKGDRAVR-ENKRIAILPDGSLRILNASKSDEGKYVCRGE 554
Query: 219 NAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIAL---ILGAFFYWRSKNKEE 275
N G++ + L V P + + G I++ C A+ L FYW K +
Sbjct: 555 NVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPI 614
Query: 276 EEEE 279
+ EE
Sbjct: 615 DFEE 618
Score = 47.0 bits (110), Expect = 3e-05
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 15/139 (10%)
Query: 104 SIFINNTQLSDTGTYQCLVNNL----------PDIGGRNIGVTGLTVLVPPSAPHCQIQG 153
+++I+ Q SD G+Y CLV N + RN GV G P H
Sbjct: 253 NLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMG--EYEPKIEVHFPFTV 310
Query: 154 SQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLY 213
+ G+ V + C + G P PT W K++ + P A + Q + I N+ +G+Y
Sbjct: 311 TAAKGTTVKMECFAL-GNPVPTITWMKVNGYI--PSKARLRKSQAVLEIPNVQLDDAGIY 367
Query: 214 QCVASNAIGTSTCLLDLQV 232
+C A N+ G ++ LQV
Sbjct: 368 ECRAENSRGKNSFRGQLQV 386
Score = 36.6 bits (83), Expect = 0.045
Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 170 GIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNIS-ALSSGLYQCVASNAIGT 223
G P P+Y W + + L + GT I N S A SG YQC+A+N +G+
Sbjct: 127 GNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGS 181
Score = 29.3 bits (64), Expect = 7.2
Identities = 29/126 (23%), Positives = 46/126 (36%), Gaps = 5/126 (3%)
Query: 105 IFINNTQLSDTGTYQCLVNN-LPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
I N ++ D+G YQCL N + I R T + + + S G V+L
Sbjct: 158 IISNPSEAKDSGHYQCLATNTVGSILSRE--ATLQFAYLGNFSGRTRSAVSVREGQGVVL 215
Query: 164 LCSSEEGIPRPTYLW--EKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAI 221
+CS P Y W + + + Q G + I + G Y C+ N +
Sbjct: 216 MCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTV 275
Query: 222 GTSTCL 227
+ L
Sbjct: 276 TNARVL 281
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 63.2 bits (152), Expect = 5e-10
Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 6/131 (4%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I N QL D G Y+C N G+N L V P D GS + C
Sbjct: 282 IPNVQLDDAGIYECRAENSR---GKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECK 338
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
+ G PRPTY W L N + L P + + V G + I N++ +G+YQC+A N G
Sbjct: 339 AT-GKPRPTYRW--LKNGVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYA 395
Query: 227 LLDLQVISPQP 237
+L++++ P
Sbjct: 396 SAELKILASAP 406
Score = 53.1 bits (126), Expect = 5e-07
Identities = 49/184 (26%), Positives = 76/184 (41%), Gaps = 11/184 (5%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLV-PPSAPHCQIQGSQDIGSD 160
N + I+N SD G YQCL N G L +L P+ Q++ + + D
Sbjct: 366 NGVLMIHNVNQSDAGMYQCLAENK---YGAIYASAELKILASAPTFALNQLKKTIIVTKD 422
Query: 161 --VILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVAS 218
V++ C +G P+PT W+K D ++ G++ I N S G Y C
Sbjct: 423 QEVVIEC-KPQGSPKPTISWKKGDRAVR-ENKRIAILPDGSLRILNASKSDEGKYVCRGE 480
Query: 219 NAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIAL---ILGAFFYWRSKNKEE 275
N G++ + L V P + + G I++ C A+ L FYW K +
Sbjct: 481 NVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPI 540
Query: 276 EEEE 279
+ EE
Sbjct: 541 DFEE 544
Score = 47.0 bits (110), Expect = 3e-05
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 15/139 (10%)
Query: 104 SIFINNTQLSDTGTYQCLVNNL----------PDIGGRNIGVTGLTVLVPPSAPHCQIQG 153
+++I+ Q SD G+Y CLV N + RN GV G P H
Sbjct: 179 NLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMG--EYEPKIEVHFPFTV 236
Query: 154 SQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLY 213
+ G+ V + C + G P PT W K++ + P A + Q + I N+ +G+Y
Sbjct: 237 TAAKGTTVKMECFAL-GNPVPTITWMKVNGYI--PSKARLRKSQAVLEIPNVQLDDAGIY 293
Query: 214 QCVASNAIGTSTCLLDLQV 232
+C A N+ G ++ LQV
Sbjct: 294 ECRAENSRGKNSFRGQLQV 312
Score = 36.6 bits (83), Expect = 0.045
Identities = 20/55 (36%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 170 GIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNIS-ALSSGLYQCVASNAIGT 223
G P P+Y W + + L + GT I N S A SG YQC+A+N +G+
Sbjct: 53 GNPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGS 107
Score = 29.3 bits (64), Expect = 7.2
Identities = 29/126 (23%), Positives = 46/126 (36%), Gaps = 5/126 (3%)
Query: 105 IFINNTQLSDTGTYQCLVNN-LPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
I N ++ D+G YQCL N + I R T + + + S G V+L
Sbjct: 84 IISNPSEAKDSGHYQCLATNTVGSILSRE--ATLQFAYLGNFSGRTRSAVSVREGQGVVL 141
Query: 164 LCSSEEGIPRPTYLW--EKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAI 221
+CS P Y W + + + Q G + I + G Y C+ N +
Sbjct: 142 MCSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTV 201
Query: 222 GTSTCL 227
+ L
Sbjct: 202 TNARVL 207
>gi|47106069 sialic acid binding Ig-like lectin 15 [Homo sapiens]
Length = 328
Score = 61.6 bits (148), Expect = 1e-09
Identities = 67/299 (22%), Positives = 113/299 (37%), Gaps = 20/299 (6%)
Query: 11 LLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALIN--LNVIWMVTPLSNAN 68
LL +H A + P + G AVLPCTFT + L IW
Sbjct: 31 LLNTEVHSSPAQRWSMQVPPEVSAEAGDAAVLPCTFTHPHRHYDGPLTAIWRAGEPYAGP 90
Query: 69 QPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDI 128
Q + +G ++ A HGR G ++S+ + L+D Y C V D+
Sbjct: 91 QVFRCAAARGSELCQTALSLHGRFRLLGNPRRNDLSLRVERLALADDRRYFCRVEFAGDV 150
Query: 129 GGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLP 188
R G+ + V + I LC++ EG P P W L
Sbjct: 151 HDRYESRHGVRLHVTAAPRIVNISVLPSPAHAFRALCTA-EGEPPPALAWSGPALGNSLA 209
Query: 189 PTATQDQVQGTVTIRNISALS-SGLYQCVASNAIGTSTCLLDLQVI--SPQPRNIGLIAG 245
+ + G + + AL+ G Y C A+N++G S + L + + L+ G
Sbjct: 210 AVRSPREGHGHLVTAELPALTHDGRYTCTAANSLGRSEASVYLFRFHGASGASTVALLLG 269
Query: 246 AIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDDLPPKCSSAKAFHTEIS 304
A+G A++++ +A R+ + E + P D PP+ + ++ + +S
Sbjct: 270 ALGFKALLLLGVLAA--------RAARRRPEHLDTP------DTPPRSQAQESNYENLS 314
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 60.8 bits (146), Expect = 2e-09
Identities = 67/242 (27%), Positives = 95/242 (39%), Gaps = 49/242 (20%)
Query: 13 LLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQ 72
L+ +H V ++ ++ P I V R + L C S+A P
Sbjct: 3613 LVRVH-VPPNIAGTDEPRDITVLRNRQVTLECK-------------------SDAVPPPV 3652
Query: 73 VILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRN 132
+ + G+ PR G + INN L DT Y C+ +N I G+
Sbjct: 3653 ITWLRNGERLQATPRVRILSG--------GRYLQINNADLGDTANYTCVASN---IAGKT 3701
Query: 133 IGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSE------EGIPRPTYLWEKLDNTLK 186
LTV VPP+ I+G S VILL S EG+P P W K L
Sbjct: 3702 TREFILTVNVPPN-----IKGGPQ--SLVILLNKSTVLECIAEGVPTPRITWRKDGAVLA 3754
Query: 187 LPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQV-----ISPQPRNIG 241
G + I++ +G Y C+A+NA GT +DLQV I+P P N+
Sbjct: 3755 GNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMT 3814
Query: 242 LI 243
+I
Sbjct: 3815 VI 3816
Score = 58.9 bits (141), Expect = 9e-09
Identities = 39/132 (29%), Positives = 58/132 (43%), Gaps = 4/132 (3%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
S+ I T+ SD+G Y C+ N I G L V VPP +G V +
Sbjct: 1134 SMKITETRTSDSGMYLCVATN---IAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDI 1190
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
C+++ G P P W K +T+ + GT++I + +G+Y CVA+N GT
Sbjct: 1191 PCNAQ-GTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAGT 1249
Query: 224 STCLLDLQVISP 235
+ L V P
Sbjct: 1250 DETEITLHVQEP 1261
Score = 58.2 bits (139), Expect = 1e-08
Identities = 49/199 (24%), Positives = 86/199 (43%), Gaps = 31/199 (15%)
Query: 25 VSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDG 84
V + P ++ V G+ AVL C ++ ++ N+ W V L + ++
Sbjct: 522 VIQVPNNVTVTPGERAVLTCLIISA---VDYNLTWQ-------RNDRDVRLAEPARI--- 568
Query: 85 APRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPP 144
N+S+ + + + +D G Y C+V++ GG + LTV PP
Sbjct: 569 -------------RTLANLSLELKSVKFNDAGEYHCMVSSE---GGSSAASVFLTVQEPP 612
Query: 145 SAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN 204
S GS+V ++CS+ G P+P W D + + + GT+ I+N
Sbjct: 613 KVTVMPKNQSFTGGSEVSIMCSAT-GYPKPKIAWTVNDMFI-VGSHRYRMTSDGTLFIKN 670
Query: 205 ISALSSGLYQCVASNAIGT 223
+ +G+Y C+ASN+ GT
Sbjct: 671 AAPKDAGIYGCLASNSAGT 689
Score = 54.7 bits (130), Expect = 2e-07
Identities = 43/130 (33%), Positives = 59/130 (45%), Gaps = 6/130 (4%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
S+ I Q D G Y C+ N + G + T LTV VPP + + + S IL
Sbjct: 4132 SLQIAFVQPGDAGHYTCMAAN---VAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAIL 4188
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQD-QVQGTVTIRNISALSSGLYQCVASNAIG 222
C ++ GIP P W+K DN L + G + + N+ SG Y CVA+NA G
Sbjct: 4189 PCVAD-GIPTPAINWKK-DNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 223 TSTCLLDLQV 232
T + L V
Sbjct: 4247 EDTHTVSLTV 4256
Score = 53.9 bits (128), Expect = 3e-07
Identities = 55/228 (24%), Positives = 82/228 (35%), Gaps = 33/228 (14%)
Query: 14 LSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQV 73
+++ G+ A L + SP V GQ LPCT + W+ P
Sbjct: 882 VTVTGLVAPL-IGISPSVANVIEGQQLTLPCTLLAGNPIPERR--WIKNSAMLLQNPYIT 938
Query: 74 ILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNI 133
+ G S+ I QL D G Y C+ +N + G N
Sbjct: 939 VRSDG-------------------------SLHIERVQLQDGGEYTCVASN---VAGTNN 970
Query: 134 GVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQ 193
T + V V P+ H Q S G V L C + G P+P+ +W K +
Sbjct: 971 KTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKAS-GNPKPSVIWSKKGELISTSSAKFS 1029
Query: 194 DQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIG 241
G++ + + SG Y C A+N G + + L V +PR G
Sbjct: 1030 AGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVY-VRPRVFG 1076
Score = 52.8 bits (125), Expect = 6e-07
Identities = 41/148 (27%), Positives = 64/148 (43%), Gaps = 9/148 (6%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
++FI N D G Y CL +N +N + L + P Q + +G ++
Sbjct: 665 TLFIKNAAPKDAGIYGCLASNSAGTDKQN---STLRYIEAPKLMVVQSELLVALGDITVM 721
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
C + GIP P W K D L+ D + G + I+ L +G Y CVA N G
Sbjct: 722 ECKTS-GIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGR 780
Query: 224 STCLLDLQVISP-----QPRNIGLIAGA 246
+T + L V SP +P ++ + G+
Sbjct: 781 ATGKITLDVGSPPVFIQEPADVSMEIGS 808
Score = 52.0 bits (123), Expect = 1e-06
Identities = 41/135 (30%), Positives = 61/135 (45%), Gaps = 6/135 (4%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
+ + Q+SDTG Y C+ N R+I L V VPP+ + S I V LLC
Sbjct: 2070 LTSAQISDTGRYTCVAVNAAGEKQRDID---LRVYVPPNIMGEEQNVSVLISQAVELLCQ 2126
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
S+ IP PT W K + L P + + + + I + +G Y C A+N G +
Sbjct: 2127 SD-AIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEK 2185
Query: 227 LLDLQVISPQPRNIG 241
++ + P NIG
Sbjct: 2186 NYNVNIWVPP--NIG 2198
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/145 (31%), Positives = 64/145 (44%), Gaps = 19/145 (13%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI-------GS 159
I + Q+ DTG Y C N+ +N V + VPP+ I GS ++ G+
Sbjct: 2161 IEDAQVQDTGRYTCEATNVAGKTEKNYNVN---IWVPPN-----IGGSDELTQLTVIEGN 2212
Query: 160 DVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG--TVTIRNISALSSGLYQCVA 217
+ LLC S GIP P +W+K + + + G + I + LY CVA
Sbjct: 2213 LISLLCESS-GIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVA 2271
Query: 218 SNAIGTSTCLLDLQV-ISPQPRNIG 241
SN GT+ +LQV I P N G
Sbjct: 2272 SNVAGTAKKEYNLQVYIRPTITNSG 2296
Score = 51.2 bits (121), Expect = 2e-06
Identities = 43/147 (29%), Positives = 66/147 (44%), Gaps = 13/147 (8%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
S+ I + + DT TY+C V N G + LTV VPPS + ++
Sbjct: 3860 SLVIISPSVDDTATYECTVTN---GAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVI 3916
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQV--QGTVTIRNISALSSGLYQCVASNAI 221
C++ G+P P+ W K N ++L P ++ G + I +G Y CVA NA
Sbjct: 3917 TCTA-SGVPFPSIHWTK--NGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAA 3973
Query: 222 GTSTCLLDLQ-----VISPQPRNIGLI 243
G++ + L VI PQP + +I
Sbjct: 3974 GSAHRHVTLHVHEPPVIQPQPSELHVI 4000
Score = 49.3 bits (116), Expect = 7e-06
Identities = 45/160 (28%), Positives = 66/160 (41%), Gaps = 13/160 (8%)
Query: 65 SNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNN 124
SNA P + Y+ G+M + H + G M + I ++SDTG Y C N
Sbjct: 3083 SNAVPPPVITWYKNGRMITEST--HVEILADGQM------LHIKKAEVSDTGQYVCRAIN 3134
Query: 125 LPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNT 184
+ GR+ L V VPPS + + + S+ + L GIP PT W K
Sbjct: 3135 ---VAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKR 3191
Query: 185 LKLPPTATQDQVQG--TVTIRNISALSSGLYQCVASNAIG 222
++ + + G + I SG Y C+ASN G
Sbjct: 3192 IENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG 3231
Score = 49.3 bits (116), Expect = 7e-06
Identities = 39/130 (30%), Positives = 59/130 (45%), Gaps = 8/130 (6%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
I +Q SD+G Y C+ +N+ G+ L++ VPPS +I + G +V L+
Sbjct: 3211 IARSQHSDSGNYTCIASNME---GKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELV 3267
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSS--GLYQCVASNAIG 222
C++ GIP P W K + T T+ AL+S G Y CVA+N G
Sbjct: 3268 CNA-NGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAG 3326
Query: 223 TSTCLLDLQV 232
+ +L V
Sbjct: 3327 EEDRIFNLNV 3336
Score = 48.5 bits (114), Expect = 1e-05
Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 6/136 (4%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDV 161
N + I + ++DTG Y C+ N R I L V VPPS + +
Sbjct: 3765 NGFLHIQSAHVTDTGRYLCMATNAAGTDRRRID---LQVHVPPSIAPGPTNMTVIVNVQT 3821
Query: 162 ILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQV--QGTVTIRNISALSSGLYQCVASN 219
L C + GIP+P+ W K + L + ++ G++ I + S + Y+C +N
Sbjct: 3822 TLACEAT-GIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 220 AIGTSTCLLDLQVISP 235
G +DL V P
Sbjct: 3881 GAGDDKRTVDLTVQVP 3896
Score = 47.8 bits (112), Expect = 2e-05
Identities = 46/189 (24%), Positives = 76/189 (40%), Gaps = 12/189 (6%)
Query: 48 TSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFI 107
TS ++ +N + + + P ++ + GQ+ D F ++ G + I
Sbjct: 1741 TSYFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGF--KILLNGR------KLVI 1792
Query: 108 NNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSS 167
Q+S+TG Y+C+ N G + +TV VPP+ + + + L
Sbjct: 1793 AQAQVSNTGLYRCMAAN---TAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCI 1849
Query: 168 EEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTV-TIRNISALSSGLYQCVASNAIGTSTC 226
GIP P+ W K D + + Q G V I +G Y CVA+NA G +
Sbjct: 1850 ANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQ 1909
Query: 227 LLDLQVISP 235
+ L V P
Sbjct: 1910 HIQLHVHEP 1918
Score = 47.4 bits (111), Expect = 3e-05
Identities = 57/207 (27%), Positives = 80/207 (38%), Gaps = 20/207 (9%)
Query: 24 EVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVT-PLSNANQPEQVILYQGGQMF 82
E + G I + G P V F A +++ + VT P PE I ++
Sbjct: 777 EAGRATGKITLDVGSPPV----FIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWR---RL 829
Query: 83 DGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNL--PDIGGRNIGVTGLT- 139
D P F + ++FI N SD GTY C N + VTGL
Sbjct: 830 DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA 889
Query: 140 --VLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ 197
+ + PS + I+G Q + L C+ G P P W K L P T +
Sbjct: 890 PLIGISPSVANV-IEGQQ-----LTLPCTLLAGNPIPERRWIKNSAMLLQNPYITV-RSD 942
Query: 198 GTVTIRNISALSSGLYQCVASNAIGTS 224
G++ I + G Y CVASN GT+
Sbjct: 943 GSLHIERVQLQDGGEYTCVASNVAGTN 969
Score = 47.4 bits (111), Expect = 3e-05
Identities = 49/213 (23%), Positives = 79/213 (37%), Gaps = 36/213 (16%)
Query: 25 VSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLS-NANQPEQVILYQGGQMFD 83
+ P + V P +LPC T + + + W ++ N + +L GG
Sbjct: 3990 IQPQPSELHVILNNPILLPCEATGTPSPF---ITWQKEGINVNTSGRNHAVLPSGGLQIS 4046
Query: 84 GAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVP 143
A R D GTY C+ N G +G L V VP
Sbjct: 4047 RAVR-------------------------EDAGTYMCVAQNP---AGTALGKIKLNVQVP 4078
Query: 144 PS-APHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTI 202
P +PH + + + + L C ++ G+P P W K D + + G++ I
Sbjct: 4079 PVISPHLK-EYVIAVDKPITLSCEAD-GLPPPDITWHK-DGRAIVESIRQRVLSSGSLQI 4135
Query: 203 RNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
+ +G Y C+A+N G+S+ L V P
Sbjct: 4136 AFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVP 4168
Score = 47.0 bits (110), Expect = 3e-05
Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 3/129 (2%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I NTQ++D G Y C+ N G L V VPPS + + + ++ I L
Sbjct: 2930 ILNTQITDIGRYVCVAENT---AGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC 2986
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
G P P W K + +KL T+ I G Y C+A N G S
Sbjct: 2987 EVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKK 3046
Query: 227 LLDLQVISP 235
L V P
Sbjct: 3047 KFSLTVYVP 3055
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/135 (25%), Positives = 57/135 (42%), Gaps = 10/135 (7%)
Query: 105 IFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI----GSD 160
I I Q+SD Y C+ +N + ++ L V PP+ + G+++I GS
Sbjct: 3398 IRIVRAQVSDVAVYTCVASNRAGVDNKHYN---LQVFAPPNMDNSM--GTEEITVLKGSS 3452
Query: 161 VILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNA 220
+ C ++ G P P+ W + L L T + + SG Y C+ASN
Sbjct: 3453 TSMACITD-GTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNE 3511
Query: 221 IGTSTCLLDLQVISP 235
G + L+V+ P
Sbjct: 3512 AGEVSKHFILKVLEP 3526
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/132 (29%), Positives = 56/132 (42%), Gaps = 5/132 (3%)
Query: 105 IFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILL 164
I I + Q+SD G Y+C+ N G L V V PS + + + V L
Sbjct: 1976 IDIESAQISDAGIYKCVAIN---SAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLE 2032
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALS-SGLYQCVASNAIGT 223
C + GIP P+ W K + + Q G + + +S +G Y CVA NA G
Sbjct: 2033 CEA-RGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 2091
Query: 224 STCLLDLQVISP 235
+DL+V P
Sbjct: 2092 KQRDIDLRVYVP 2103
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 19/145 (13%)
Query: 100 ATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGS 159
A ++ I SDTG Y C+ N G + L V V P+ I+G++D
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNP---AGEEDRIFNLNVYVTPT-----IRGNKDEAE 3350
Query: 160 DVILLCSSE-------EGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSS-- 210
++ L + G P P W L N L LP ++ + IR + A S
Sbjct: 3351 KLMTLVDTSINIECRATGTPPPQINW--LKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDV 3408
Query: 211 GLYQCVASNAIGTSTCLLDLQVISP 235
+Y CVASN G +LQV +P
Sbjct: 3409 AVYTCVASNRAGVDNKHYNLQVFAP 3433
Score = 42.4 bits (98), Expect = 8e-04
Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 6/137 (4%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPS--APHCQIQGSQDIGSDVILL 164
+ N +SDTG Y C+ N + G L+V PPS H + + + + L
Sbjct: 2350 LKNIHVSDTGRYVCVAVN---VAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSL 2406
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTS 224
GIP P+ W K + L + + + + +G Y CV NA G
Sbjct: 2407 TCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEE 2466
Query: 225 TCLLDLQVISPQPRNIG 241
+ L V+ P P +G
Sbjct: 2467 RKIFGLSVLVP-PHIVG 2482
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/156 (25%), Positives = 62/156 (39%), Gaps = 17/156 (10%)
Query: 105 IFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILL 164
+ + N + +D G YQC V+N G+ LT+ +PPS I+G ++ +D+ +L
Sbjct: 1510 LHLKNARRNDKGRYQCTVSN---AAGKQAKDIKLTIYIPPS-----IKGG-NVTTDISVL 1560
Query: 165 CSS-------EEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
+S G+P P W K + A + I S Y C
Sbjct: 1561 INSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHV 1620
Query: 218 SNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVI 253
+N GT+ + V P P G +A + VI
Sbjct: 1621 ANVAGTAEKSFHVDVYVP-PMIEGNLATPLNKQVVI 1655
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/152 (27%), Positives = 61/152 (40%), Gaps = 24/152 (15%)
Query: 100 ATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHC-QIQGSQDIG 158
A ++ I Q+SDTG Y C+ +N I G + + + VPPS +I D G
Sbjct: 2725 ANGHTLQIKEAQISDTGRYTCVASN---IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTG 2781
Query: 159 -----SDVIL-----LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQV-----QGTVTIR 203
DVI+ L P PT W K + P + D+V + I
Sbjct: 2782 RNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDKVLILPGGRVLQIP 2836
Query: 204 NISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
+G Y CVA N G + D++V+ P
Sbjct: 2837 RAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVP 2868
Score = 41.6 bits (96), Expect = 0.001
Identities = 38/149 (25%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI---GSDVIL 163
I+ + SD Y C+ +N+ + L V + P+ + ++ I G + L
Sbjct: 2256 ISIAEKSDAALYSCVASNVAGTAKKEYN---LQVYIRPTITNSGSHPTEIIVTRGKSISL 2312
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVT-IRNISALSSGLYQCVASNAIG 222
C + GIP PT W K + L + + +G + ++NI +G Y CVA N G
Sbjct: 2313 ECEVQ-GIPPPTVTWMKDGHPL-IKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Query: 223 TSTCLLDLQVISP--------QPRNIGLI 243
+ DL V +P P NI ++
Sbjct: 2371 MTDKKYDLSVHAPPSIIGNHRSPENISVV 2399
Score = 40.4 bits (93), Expect = 0.003
Identities = 43/152 (28%), Positives = 66/152 (43%), Gaps = 15/152 (9%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHC--QIQGSQDIGSDVILL 164
I T L D G Y C+ N ++I L V PPS + + + + V L
Sbjct: 1885 IAKTLLEDAGRYTCVATNAAGETQQHIQ---LHVHEPPSLEDAGKMLNETVLVSNPVQLE 1941
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVT-IRNISALSSGLYQCVASNAIGT 223
C + G P P W K DN L T+ +G + I + +G+Y+CVA N+ G
Sbjct: 1942 CKAA-GNPVPVITWYK-DNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGA 1999
Query: 224 STCLLDLQV-ISPQPRNIGLIAGAIGTGAVII 254
+ LQV ++P I+G+ AV++
Sbjct: 2000 TELFYSLQVHVAPS------ISGSNNMVAVVV 2025
Score = 40.0 bits (92), Expect = 0.004
Identities = 37/141 (26%), Positives = 57/141 (40%), Gaps = 14/141 (9%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
S+++ + ++G Y C N R + LTV V P Q SQD ++ +
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQ---LTVYVRPRVFGDQRGLSQDKPVEISV 1091
Query: 164 LCSSE-------EGIPRPTYLWEKLDNTLKLPPTATQDQV--QGTVTIRNISALSSGLYQ 214
L E + +P P W K T + P + + G++ I SG+Y
Sbjct: 1092 LAGEEVTLPCEVKSLPPPIITWAK--ETQLISPFSPRHTFLPSGSMKITETRTSDSGMYL 1149
Query: 215 CVASNAIGTSTCLLDLQVISP 235
CVA+N G T + L V P
Sbjct: 1150 CVATNIAGNVTQAVKLNVHVP 1170
Score = 38.9 bits (89), Expect = 0.009
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 8/157 (5%)
Query: 105 IFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGS--QDIGSDVI 162
+ I D+GTY C N + G + P + + +G + I
Sbjct: 4313 LVIERVSKEDSGTYVCTAENSVGF----VKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAI 4368
Query: 163 LLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
L C + G P PT W + +++ Q G++ I +G Y CVA+N G
Sbjct: 4369 LNCEVK-GDPTPTIQWNRKGVDIEISHRIRQ-LGNGSLAIYGTVNEDAGDYTCVATNEAG 4426
Query: 223 TSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIA 259
+ L + SP + + I G II+ C A
Sbjct: 4427 VVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQA 4463
Score = 38.9 bits (89), Expect = 0.009
Identities = 31/126 (24%), Positives = 57/126 (45%), Gaps = 13/126 (10%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDV 161
N S+ I T D G Y C+ N + R++ LT+ PP ++ + G +
Sbjct: 4401 NGSLAIYGTVNEDAGDYTCVATNEAGVVERSM---SLTLQSPPIITLEPVETVINAGGKI 4457
Query: 162 ILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQV----QGTVTIRNISALSSGLYQCVA 217
IL C + G P+PT W + +++ + D+V ++ I + + ++CVA
Sbjct: 4458 ILNCQA-TGEPQPTITWSRQGHSI-----SWDDRVNVLSNNSLYIADAQKEDTSEFECVA 4511
Query: 218 SNAIGT 223
N +G+
Sbjct: 4512 RNLMGS 4517
Score = 38.5 bits (88), Expect = 0.012
Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 4/132 (3%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
+I I TQL+ G Y C+ N R++ L V PP + + + ++L
Sbjct: 3951 AIEILATQLNHAGRYTCVARNAAGSAHRHVT---LHVHEPPVIQPQPSELHVILNNPILL 4007
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
C + G P P W+K + G + I +G Y CVA N GT
Sbjct: 4008 PCEAT-GTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGT 4066
Query: 224 STCLLDLQVISP 235
+ + L V P
Sbjct: 4067 ALGKIKLNVQVP 4078
Score = 37.0 bits (84), Expect = 0.035
Identities = 35/137 (25%), Positives = 54/137 (39%), Gaps = 8/137 (5%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSA----PHCQIQGSQDIGS 159
++ I+ SD G Y C+ N I G + L V PP+ P + + +
Sbjct: 1225 TLSIDQATPSDAGIYTCVATN---IAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVAN 1281
Query: 160 DVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTV-TIRNISALSSGLYQCVAS 218
I +G P+PT W L GT+ I +++ +G Y CVA
Sbjct: 1282 QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAV 1341
Query: 219 NAIGTSTCLLDLQVISP 235
N GT+ +L+V P
Sbjct: 1342 NEAGTTERKYNLKVHVP 1358
Score = 36.2 bits (82), Expect = 0.059
Identities = 39/161 (24%), Positives = 69/161 (42%), Gaps = 17/161 (10%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I + Q D G Y C+ + + G + VLVPP+ I+G + ++++ +
Sbjct: 1699 IMSAQEIDRGQYICVATS---VAGEKEIKYEVDVLVPPA-----IEGGDETSYFIVMVNN 1750
Query: 167 SEE------GIPRPTYLWEKLDNTLKLPPTATQDQVQGT-VTIRNISALSSGLYQCVASN 219
E G P PT +W K D L + + G + I ++GLY+C+A+N
Sbjct: 1751 LLELDCHVTGSPPPTIMWLK-DGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAAN 1809
Query: 220 AIGTSTCLLDLQV-ISPQPRNIGLIAGAIGTGAVIIIFCIA 259
G ++ V + P ++ GL + + + CIA
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIA 1850
Score = 35.8 bits (81), Expect = 0.077
Identities = 37/144 (25%), Positives = 56/144 (38%), Gaps = 9/144 (6%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD-----IGSDV 161
I N Q+ TG Y CL ++ R+ L V V P+ G+ + + S
Sbjct: 2537 ITNVQVPHTGRYTCLASSPAGHKSRSFS---LNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 162 ILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAI 221
L+C + P T W K L+ T+ I N ++G Y CVA+N
Sbjct: 2594 SLVCEAYS-YPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEA 2652
Query: 222 GTSTCLLDLQVISPQPRNIGLIAG 245
G +++V P N G + G
Sbjct: 2653 GEMIKHYEVKVYIPPIINKGDLWG 2676
Score = 35.8 bits (81), Expect = 0.077
Identities = 42/157 (26%), Positives = 59/157 (37%), Gaps = 10/157 (6%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI----GSDVI 162
I+ Q+ DTG Y CL ++ + V V VPP+ +DI V
Sbjct: 3586 ISTAQVEDTGRYTCLASSPAGDDDKEYLV---RVHVPPNI--AGTDEPRDITVLRNRQVT 3640
Query: 163 LLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
L C S + +P P W + L+ P + I N + Y CVASN G
Sbjct: 3641 LECKS-DAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAG 3699
Query: 223 TSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIA 259
+T L V P G + I ++ CIA
Sbjct: 3700 KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIA 3736
Score = 35.4 bits (80), Expect = 0.10
Identities = 35/163 (21%), Positives = 66/163 (40%), Gaps = 9/163 (5%)
Query: 100 ATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI-- 157
+ +V++ I LSD G Y+C+ G T V PP P Q+ + +
Sbjct: 479 SASVNLDIAKVTLSDEGFYECIA---VSSAGTGRAQTFFDVSEPP--PVIQVPNNVTVTP 533
Query: 158 GSDVILLCSSEEGIPRPTYLWEKLDNTLKL-PPTATQDQVQGTVTIRNISALSSGLYQCV 216
G +L C + W++ D ++L P + ++ ++++ +G Y C+
Sbjct: 534 GERAVLTCLIISAVDY-NLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCM 592
Query: 217 ASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIA 259
S+ G+S + L V P + + G+ + I C A
Sbjct: 593 VSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSA 635
Score = 33.9 bits (76), Expect = 0.29
Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 7/130 (5%)
Query: 114 DTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHC-QIQGSQDIGSDVILLCSSEEGIP 172
D G Y C+ N R L V VPP Q+ + + + L EG P
Sbjct: 1332 DNGEYICVAVNEAGTTERKYN---LKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTP 1388
Query: 173 RPTYLWEKLDNTLKLPPTATQDQVQGTVT-IRNISALSSGLYQCVASNAIGTSTCLLDLQ 231
P +W K DN + Q G + + + +G Y C A N GTS ++
Sbjct: 1389 SPIIMWYK-DNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNID 1447
Query: 232 VISPQPRNIG 241
V+ P P IG
Sbjct: 1448 VLVP-PTIIG 1456
>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
Length = 2623
Score = 60.8 bits (146), Expect = 2e-09
Identities = 45/141 (31%), Positives = 67/141 (47%), Gaps = 8/141 (5%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQG-SQDIGSD 160
N ++ I ++ D G Y C +NL G ++ VT V PP + + + GS
Sbjct: 1705 NGTLSIQRVEIQDRGQYLCSASNL--FGTDHLHVTLSVVSYPPRILERRTKEITVHSGST 1762
Query: 161 VILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQ----VQGTVTIRNISALSSGLYQCV 216
V L C +E G P PT W + T+ + Q V GT+ + N+S G Y+CV
Sbjct: 1763 VELKCRAE-GRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCV 1821
Query: 217 ASNAIGTSTCLLDLQVISPQP 237
ASN G + L+ +QVI+ P
Sbjct: 1822 ASNPGGQDSLLVKIQVIAAPP 1842
Score = 50.4 bits (119), Expect = 3e-06
Identities = 36/143 (25%), Positives = 63/143 (44%), Gaps = 18/143 (12%)
Query: 101 TNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSD 160
+N +++I N SD GTY+C+ + R + +T + P + ++ D
Sbjct: 1898 SNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGD 1957
Query: 161 VILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ-----------GTVTIRNISALS 209
+LL S G P+P +W +LP A DQ G++ I +++
Sbjct: 1958 KLLLNCSATGEPKPQIMW-------RLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKD 2010
Query: 210 SGLYQCVASNAIGTSTCLLDLQV 232
SG+Y CVA N +G L+ + +
Sbjct: 2011 SGVYLCVARNKMGDDLILMHVSL 2033
Score = 50.4 bits (119), Expect = 3e-06
Identities = 48/200 (24%), Positives = 81/200 (40%), Gaps = 22/200 (11%)
Query: 70 PEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNN----L 125
PE + + G F P+ + + A+N S I+ T D G Y+C N +
Sbjct: 2367 PEIIWILPNGTRFSNGPQSYQY------LIASNGSFIISKTTREDAGKYRCAARNKVGYI 2420
Query: 126 PDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTL 185
+ IG + + P ++G G + L C S+ GIP+P W +
Sbjct: 2421 EKLVILEIGQKPVILTYAPGT----VKGIS--GESLSLHCVSD-GIPKPNIKWTMPSGYV 2473
Query: 186 KLPPTATQDQV---QGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGL 242
P + GT+ I+ +A G Y C A N++G + + + +++ PR
Sbjct: 2474 VDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNR 2533
Query: 243 IAGAI--GTGAVIIIFCIAL 260
+I TGA + C+AL
Sbjct: 2534 PPRSIVTRTGAAFQLHCVAL 2553
Score = 50.1 bits (118), Expect = 4e-06
Identities = 42/168 (25%), Positives = 81/168 (48%), Gaps = 18/168 (10%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI----GS 159
++ ++N + D G Y+C+ +N GG++ + + V+ P P Q Q I G
Sbjct: 1804 TLVLHNLSIYDRGFYKCVASNP---GGQDSLLVKIQVIAAP--PVILEQRRQVIVGTWGE 1858
Query: 160 DVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQV----QGTVTIRNISALSSGLYQC 215
+ L C+++ G P+P+ W D T P T ++ GT+ IRN+++ G Y+C
Sbjct: 1859 SLKLPCTAK-GTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYEC 1917
Query: 216 VASNAIGTSTCLLDL----QVISPQPRNIGLIAGAIGTGAVIIIFCIA 259
+A+++ G+ ++ L +V SP+ + G +++ C A
Sbjct: 1918 IATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSA 1965
Score = 50.1 bits (118), Expect = 4e-06
Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 8/138 (5%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDV 161
N ++ I D G Y C N +G I V + V PP + +
Sbjct: 2488 NGTLVIKEATAYDRGNYICKAQN--SVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAA 2545
Query: 162 ILLCSSEEGIPRPTYLWEKLDNTLKLPPT------ATQDQVQGTVTIRNISALSSGLYQC 215
L G+P+P WE D++L + + Q +QGT+ I+N SG+Y+C
Sbjct: 2546 FQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKC 2605
Query: 216 VASNAIGTSTCLLDLQVI 233
A N +G+ +QVI
Sbjct: 2606 TAKNPLGSDYAATYIQVI 2623
Score = 47.0 bits (110), Expect = 3e-05
Identities = 35/142 (24%), Positives = 53/142 (37%), Gaps = 3/142 (2%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDV 161
N +++ N +++ G Y C N +G + V + P + D
Sbjct: 2101 NGTLYFNKVGVAEEGDYTCYAQNT--LGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDT 2158
Query: 162 ILLCSSEEGIPRPTYLWEKLDNTL-KLPPTATQDQVQGTVTIRNISALSSGLYQCVASNA 220
+L G P+P W N + G++TI + L SG Y CVA N
Sbjct: 2159 AVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNP 2218
Query: 221 IGTSTCLLDLQVISPQPRNIGL 242
G T + L V+S P GL
Sbjct: 2219 SGDDTKMYKLDVVSKPPLINGL 2240
Score = 45.1 bits (105), Expect = 1e-04
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 5/84 (5%)
Query: 159 SDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ----GTVTIRNISALSSGLYQ 214
SD L C + G P PT W ++ + L L +VQ GT++I+ + G Y
Sbjct: 1664 SDAFLPCEAV-GNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYL 1722
Query: 215 CVASNAIGTSTCLLDLQVISPQPR 238
C ASN GT + L V+S PR
Sbjct: 1723 CSASNLFGTDHLHVTLSVVSYPPR 1746
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/140 (26%), Positives = 56/140 (40%), Gaps = 11/140 (7%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDV 161
N S+ IN +L D+G Y C+ N G + + L V+ P + I +
Sbjct: 2195 NGSLTINKVKLLDSGEYVCVARNP---SGDDTKMYKLDVVSKPPLINGLYTNRTVIKATA 2251
Query: 162 ILLCSSE-----EGIPRPTYLWEKLDNTLKLPP---TATQDQVQGTVTIRNISALSSGLY 213
+ EG P P +W DN P + GT+ IRN+ S +
Sbjct: 2252 VRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADF 2311
Query: 214 QCVASNAIGTSTCLLDLQVI 233
CVA N G S ++ L+V+
Sbjct: 2312 ICVARNEGGESVLVVQLEVL 2331
Score = 39.3 bits (90), Expect = 0.007
Identities = 32/120 (26%), Positives = 51/120 (42%), Gaps = 3/120 (2%)
Query: 114 DTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPR 173
DTG Y C+ +N D +T + LV + I + IG + L C S GIP
Sbjct: 545 DTGVYHCISSNYDDADILTYRITVVEPLVEAYQEN-GIHHTVFIGETLDLPCHST-GIPD 602
Query: 174 PTYLWEKLDNTLKLPPTATQDQVQ-GTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQV 232
+ W N + + + + GT+ I ++ G Y+CVA+N G + + V
Sbjct: 603 ASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSGVDFLIFQVSV 662
Score = 29.3 bits (64), Expect = 7.2
Identities = 19/84 (22%), Positives = 34/84 (40%), Gaps = 6/84 (7%)
Query: 157 IGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQD-----QVQGTVTIRNISALSSG 211
+G V L C + G P P W D + P ++D G + ++ + +G
Sbjct: 489 VGGTVGLNCPGQ-GDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTG 547
Query: 212 LYQCVASNAIGTSTCLLDLQVISP 235
+Y C++SN + V+ P
Sbjct: 548 VYHCISSNYDDADILTYRITVVEP 571
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 60.5 bits (145), Expect = 3e-09
Identities = 62/224 (27%), Positives = 88/224 (39%), Gaps = 43/224 (19%)
Query: 21 ASLEVS-------ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQV 73
ASLEV+ ++P + VA G+PAV+ C PE
Sbjct: 122 ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQ-------------------PPRGHPEPT 162
Query: 74 ILYQ--GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGR 131
I ++ G + D R R G + I T+ SD G Y C+ N+ +G R
Sbjct: 163 ISWKKDGSPLDDKDERITIRGG----------KLMITYTRKSDAGKYVCVGTNM--VGER 210
Query: 132 NIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTA 191
V LTVL PS + + C + G P PT W K D +LP +
Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR-GDPVPTVRWRKDDG--ELPKSR 267
Query: 192 TQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
+ + T+ IR ++A G Y CVA N +G + L V P
Sbjct: 268 YEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEP 311
Score = 40.0 bits (92), Expect = 0.004
Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPD--IGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSD-VIL 163
I N Q SD G Y C N+ I + VT + PP Q +Q + D +
Sbjct: 376 ITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTVAVDGTFV 434
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
L G P PT LW K + + + G + IR +G Y C+AS G
Sbjct: 435 LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGE 494
Query: 224 ST--CLLDLQ-----VISPQPRNIGLIAGA 246
+T +++Q V P+P + LI A
Sbjct: 495 ATWSAYIEVQEFGVPVQPPRPTDPNLIPSA 524
>gi|67188443 CD276 antigen isoform a [Homo sapiens]
Length = 534
Score = 60.5 bits (145), Expect = 3e-09
Identities = 69/305 (22%), Positives = 121/305 (39%), Gaps = 49/305 (16%)
Query: 1 MTSQRSPLAPLLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTSA--ALINLNVI 58
+T QRSP A ++V E P + G A L C+F+ +L LN+I
Sbjct: 237 ITPQRSPTG----------AVEVQVPEDP--VVALVGTDATLRCSFSPEPGFSLAQLNLI 284
Query: 59 WMVTPLSNANQPEQVILYQGGQMFDGAPRFHGRVG-FTGTMPATNVSIFINNTQLSDTGT 117
W +T +++ + D + R F + N S+ + +++D G+
Sbjct: 285 WQLTDTKQ-------LVHSFTEGRDQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGS 337
Query: 118 YQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILLCSSEEGIPRPT 175
+ C V+ + D G + L V P S P ++ ++D+ G V + CSS G P
Sbjct: 338 FTCFVS-IRDFGSAAVS---LQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAE 393
Query: 176 YLWEKLDNTLKLPPTATQDQV---QGTVTIRNISAL---SSGLYQCVASNAI------GT 223
W+ + L T Q+ QG + ++ + ++G Y C+ N + G+
Sbjct: 394 VFWQD-GQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGS 452
Query: 224 STCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNE 283
T P+ + +G +I +AL AF WR + EEE E
Sbjct: 453 VTITGQPMTFPPEALWV-----TVGLSVCLIALLVAL---AFVCWRKIKQSCEEENAGAE 504
Query: 284 IREDD 288
++ +
Sbjct: 505 DQDGE 509
Score = 56.2 bits (134), Expect = 6e-08
Identities = 52/214 (24%), Positives = 92/214 (42%), Gaps = 23/214 (10%)
Query: 19 VAASLEVSESPGSIQVARGQPAVLPCTFTTSA--ALINLNVIWMVTPLSNANQPEQVILY 76
+ +LEV + G A L C+F+ +L LN+IW +T + + V +
Sbjct: 25 LTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLT-----DTKQLVHSF 79
Query: 77 QGGQMFDGAPRFHGRVG-FTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGV 135
GQ D + R F + N S+ + +++D G++ C V+ + D G +
Sbjct: 80 AEGQ--DQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS-IRDFGSAAVS- 135
Query: 136 TGLTVLVPPSAPHCQIQGSQDI--GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQ 193
L V P S P ++ ++D+ G V + CSS +G P W+ + L T
Sbjct: 136 --LQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQD-GQGVPLTGNVTT 192
Query: 194 DQV---QGTVTIRNISAL---SSGLYQCVASNAI 221
Q+ QG + +I + ++G Y C+ N +
Sbjct: 193 SQMANEQGLFDVHSILRVVLGANGTYSCLVRNPV 226
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 60.5 bits (145), Expect = 3e-09
Identities = 62/224 (27%), Positives = 88/224 (39%), Gaps = 43/224 (19%)
Query: 21 ASLEVS-------ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQV 73
ASLEV+ ++P + VA G+PAV+ C PE
Sbjct: 161 ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQ-------------------PPRGHPEPT 201
Query: 74 ILYQ--GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGR 131
I ++ G + D R R G + I T+ SD G Y C+ N+ +G R
Sbjct: 202 ISWKKDGSPLDDKDERITIRGG----------KLMITYTRKSDAGKYVCVGTNM--VGER 249
Query: 132 NIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTA 191
V LTVL PS + + C + G P PT W K D +LP +
Sbjct: 250 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR-GDPVPTVRWRKDDG--ELPKSR 306
Query: 192 TQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
+ + T+ IR ++A G Y CVA N +G + L V P
Sbjct: 307 YEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEP 350
Score = 40.0 bits (92), Expect = 0.004
Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPD--IGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSD-VIL 163
I N Q SD G Y C N+ I + VT + PP Q +Q + D +
Sbjct: 415 ITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTVAVDGTFV 473
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
L G P PT LW K + + + G + IR +G Y C+AS G
Sbjct: 474 LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGE 533
Query: 224 ST--CLLDLQ-----VISPQPRNIGLIAGA 246
+T +++Q V P+P + LI A
Sbjct: 534 ATWSAYIEVQEFGVPVQPPRPTDPNLIPSA 563
>gi|224994173 roundabout 1 isoform d [Homo sapiens]
Length = 1551
Score = 60.1 bits (144), Expect = 4e-09
Identities = 64/228 (28%), Positives = 92/228 (40%), Gaps = 45/228 (19%)
Query: 21 ASLEVS-------ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQV 73
ASLEV+ ++P + VA G+PAV+ C PE
Sbjct: 122 ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQ-------------------PPRGHPEPT 162
Query: 74 ILYQ--GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGR 131
I ++ G + D R R G + I T+ SD G Y C+ N+ +G R
Sbjct: 163 ISWKKDGSPLDDKDERITIRGG----------KLMITYTRKSDAGKYVCVGTNM--VGER 210
Query: 132 NIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTA 191
V LTVL PS + + C + G P PT W K D +LP +
Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR-GDPVPTVRWRKDDG--ELPKSR 267
Query: 192 TQDQVQGTVTIRNISALSSGLYQCVASNAIG--TSTCLLDLQVISPQP 237
+ + T+ IR ++A G Y CVA N +G ++ L +QV S P
Sbjct: 268 YEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPP 315
Score = 40.0 bits (92), Expect = 0.004
Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPD--IGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSD-VIL 163
I N Q SD G Y C N+ I + VT + PP Q +Q + D +
Sbjct: 379 ITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTVAVDGTFV 437
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
L G P PT LW K + + + G + IR +G Y C+AS G
Sbjct: 438 LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGE 497
Query: 224 ST--CLLDLQ-----VISPQPRNIGLIAGA 246
+T +++Q V P+P + LI A
Sbjct: 498 ATWSAYIEVQEFGVPVQPPRPTDPNLIPSA 527
>gi|224994171 roundabout 1 isoform c [Homo sapiens]
Length = 1606
Score = 60.1 bits (144), Expect = 4e-09
Identities = 64/228 (28%), Positives = 92/228 (40%), Gaps = 45/228 (19%)
Query: 21 ASLEVS-------ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQV 73
ASLEV+ ++P + VA G+PAV+ C PE
Sbjct: 122 ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQ-------------------PPRGHPEPT 162
Query: 74 ILYQ--GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGR 131
I ++ G + D R R G + I T+ SD G Y C+ N+ +G R
Sbjct: 163 ISWKKDGSPLDDKDERITIRGG----------KLMITYTRKSDAGKYVCVGTNM--VGER 210
Query: 132 NIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTA 191
V LTVL PS + + C + G P PT W K D +LP +
Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR-GDPVPTVRWRKDDG--ELPKSR 267
Query: 192 TQDQVQGTVTIRNISALSSGLYQCVASNAIG--TSTCLLDLQVISPQP 237
+ + T+ IR ++A G Y CVA N +G ++ L +QV S P
Sbjct: 268 YEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPP 315
Score = 40.0 bits (92), Expect = 0.004
Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPD--IGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSD-VIL 163
I N Q SD G Y C N+ I + VT + PP Q +Q + D +
Sbjct: 379 ITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTVAVDGTFV 437
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
L G P PT LW K + + + G + IR +G Y C+AS G
Sbjct: 438 LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGE 497
Query: 224 ST--CLLDLQ-----VISPQPRNIGLIAGA 246
+T +++Q V P+P + LI A
Sbjct: 498 ATWSAYIEVQEFGVPVQPPRPTDPNLIPSA 527
>gi|13376852 CD276 antigen isoform b [Homo sapiens]
Length = 316
Score = 60.1 bits (144), Expect = 4e-09
Identities = 66/287 (22%), Positives = 116/287 (40%), Gaps = 37/287 (12%)
Query: 19 VAASLEVSESPGSIQVARGQPAVLPCTFTTSA--ALINLNVIWMVTPLSNANQPEQVILY 76
+ +LEV + G A L C+F+ +L LN+IW +T + + V +
Sbjct: 25 LTGALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLT-----DTKQLVHSF 79
Query: 77 QGGQMFDGAPRFHGRVG-FTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGV 135
GQ D + R F + N S+ + +++D G++ C V+ + D G +
Sbjct: 80 AEGQ--DQGSAYANRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVS-IRDFGSAAVS- 135
Query: 136 TGLTVLVPPSAPHCQIQGSQDI--GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQ 193
L V P S P ++ ++D+ G V + CSS G P W+ + L T
Sbjct: 136 --LQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQD-GQGVPLTGNVTT 192
Query: 194 DQV---QGTVTIRNISAL---SSGLYQCVASNAI------GTSTCLLDLQVISPQPRNIG 241
Q+ QG + ++ + ++G Y C+ N + G+ T P+ +
Sbjct: 193 SQMANEQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEALWV- 251
Query: 242 LIAGAIGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIREDD 288
+G +I +AL AF WR + EEE E ++ +
Sbjct: 252 ----TVGLSVCLIALLVAL---AFVCWRKIKQSCEEENAGAEDQDGE 291
>gi|239748173 PREDICTED: similar to roundabout 1 isoform 1 [Homo
sapiens]
Length = 1562
Score = 60.1 bits (144), Expect = 4e-09
Identities = 64/228 (28%), Positives = 92/228 (40%), Gaps = 45/228 (19%)
Query: 21 ASLEVS-------ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQV 73
ASLEV+ ++P + VA G+PAV+ C PE
Sbjct: 122 ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQ-------------------PPRGHPEPT 162
Query: 74 ILYQ--GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGR 131
I ++ G + D R R G + I T+ SD G Y C+ N+ +G R
Sbjct: 163 ISWKKDGSPLDDKDERITIRGG----------KLMITYTRKSDAGKYVCVGTNM--VGER 210
Query: 132 NIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTA 191
V LTVL PS + + C + G P PT W K D +LP +
Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR-GDPVPTVRWRKDDG--ELPKSR 267
Query: 192 TQDQVQGTVTIRNISALSSGLYQCVASNAIG--TSTCLLDLQVISPQP 237
+ + T+ IR ++A G Y CVA N +G ++ L +QV S P
Sbjct: 268 YEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPP 315
Score = 40.0 bits (92), Expect = 0.004
Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPD--IGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSD-VIL 163
I N Q SD G Y C N+ I + VT + PP Q +Q + D +
Sbjct: 379 ITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTVAVDGTFV 437
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
L G P PT LW K + + + G + IR +G Y C+AS G
Sbjct: 438 LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGE 497
Query: 224 ST--CLLDLQ-----VISPQPRNIGLIAGA 246
+T +++Q V P+P + LI A
Sbjct: 498 ATWSAYIEVQEFGVPVQPPRPTDPNLIPSA 527
>gi|239748171 PREDICTED: similar to roundabout 1 isoform 2 [Homo
sapiens]
Length = 1615
Score = 60.1 bits (144), Expect = 4e-09
Identities = 64/228 (28%), Positives = 92/228 (40%), Gaps = 45/228 (19%)
Query: 21 ASLEVS-------ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQV 73
ASLEV+ ++P + VA G+PAV+ C PE
Sbjct: 122 ASLEVAILRDDFRQNPSDVMVAVGEPAVMECQ-------------------PPRGHPEPT 162
Query: 74 ILYQ--GGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGR 131
I ++ G + D R R G + I T+ SD G Y C+ N+ +G R
Sbjct: 163 ISWKKDGSPLDDKDERITIRGG----------KLMITYTRKSDAGKYVCVGTNM--VGER 210
Query: 132 NIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTA 191
V LTVL PS + + C + G P PT W K D +LP +
Sbjct: 211 ESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR-GDPVPTVRWRKDDG--ELPKSR 267
Query: 192 TQDQVQGTVTIRNISALSSGLYQCVASNAIG--TSTCLLDLQVISPQP 237
+ + T+ IR ++A G Y CVA N +G ++ L +QV S P
Sbjct: 268 YEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPP 315
Score = 40.0 bits (92), Expect = 0.004
Identities = 42/150 (28%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPD--IGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSD-VIL 163
I N Q SD G Y C N+ I + VT + PP Q +Q + D +
Sbjct: 379 ITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIR-QGPVNQTVAVDGTFV 437
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
L G P PT LW K + + + G + IR +G Y C+AS G
Sbjct: 438 LSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGE 497
Query: 224 ST--CLLDLQ-----VISPQPRNIGLIAGA 246
+T +++Q V P+P + LI A
Sbjct: 498 ATWSAYIEVQEFGVPVQPPRPTDPNLIPSA 527
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 58.5 bits (140), Expect = 1e-08
Identities = 45/150 (30%), Positives = 69/150 (46%), Gaps = 13/150 (8%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI---- 157
N S+ I+ T+ D G YQCL N + + + +LV SAP Q++ QD+
Sbjct: 3079 NGSLTIHRTERDDAGRYQCLAENEMGVAKK------VVILVLQSAPVFQVE-PQDMTVRS 3131
Query: 158 GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
G DV L C + G P PT W + L+ + G++ + N+ +G Y CVA
Sbjct: 3132 GDDVALRCQAT-GEPTPTIEWLQAGQPLRAS-RRLRTLPDGSLWLENVETGDAGTYDCVA 3189
Query: 218 SNAIGTSTCLLDLQVISPQPRNIGLIAGAI 247
N +G++T L V + G + G I
Sbjct: 3190 HNLLGSATARAFLVVRGEPQGSWGSMTGVI 3219
Score = 53.9 bits (128), Expect = 3e-07
Identities = 43/132 (32%), Positives = 61/132 (46%), Gaps = 7/132 (5%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAP-HCQIQGSQDIGSDVILLC 165
I QLSD G+Y+C+ +N + G GL V VPP + G + + V L C
Sbjct: 752 IEQAQLSDAGSYRCVASN---VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 808
Query: 166 SSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG--TVTIRNISALSSGLYQCVASNAIGT 223
++ G P PT +W K N + T G +T+ + A SG Y CVA +A+G
Sbjct: 809 NAT-GAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGE 867
Query: 224 STCLLDLQVISP 235
+ LQV P
Sbjct: 868 DRQDVVLQVHMP 879
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 9/116 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQG-SQDIGSDVILLC 165
I Q+SD G Y C V+N + G + LTV VPP+ + + + SQ GS ++L C
Sbjct: 1899 IQEAQVSDKGLYSCKVSN---VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 1955
Query: 166 SSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ--GTVTIRNISALSSGLYQCVASN 219
G+P PT W L + + + +A V G + + + +G Y CVA N
Sbjct: 1956 DVS-GVPAPTVTW--LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 2008
Score = 52.4 bits (124), Expect = 8e-07
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 114 DTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPR 173
D G Y C+ N G +G T L V VPP + S GS L C + G P
Sbjct: 2820 DAGNYLCIAKNS---AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKAR-GSPE 2875
Query: 174 PTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVI 233
P W+K + Q G + ++N+ +G Y C A NA+G + + L ++
Sbjct: 2876 PNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL 2935
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/225 (24%), Positives = 96/225 (42%), Gaps = 34/225 (15%)
Query: 25 VSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDG 84
++ SP ++ + PA+LPC + S + V+W ++ GQ D
Sbjct: 2575 IAPSPSNLTLTAHTPALLPCEASGSPKPL---VVW----------------WKDGQKLD- 2614
Query: 85 APRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPP 144
F + G +P+ + + Q D+ ++C+V+N ++G + + +TV VPP
Sbjct: 2615 ---FRLQQGAYRLLPSNALLLTAPGPQ--DSAQFECVVSN--EVGEAH-RLYQVTVHVPP 2666
Query: 145 SAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN 204
+ Q + + + V+L C S GIP PT W K L + + G + I
Sbjct: 2667 TIADDQTDFTVTMMAPVVLTCHST-GIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQ 2725
Query: 205 ISALSSGLYQCVASNAIGTS--TCLLDLQ---VISPQPRNIGLIA 244
+ +G Y C A N+ G + L +Q V+ P P + +A
Sbjct: 2726 ALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 2770
Score = 48.9 bits (115), Expect = 9e-06
Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
+ TQ D+G Y CL +N RN V VLVPPS + ++ + G L+
Sbjct: 1219 MTQTQEQDSGLYSCLASNEAGEARRNFSVE---VLVPPSIENEDLEEVIKVLDGQTAHLM 1275
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPT--ATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
C+ G P+P W K L + D V V N+S S+G Y C+A+NA+G
Sbjct: 1276 CNVT-GHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLS--SAGHYSCIAANAVG 1332
Query: 223 TSTCLLDLQVI 233
T L V+
Sbjct: 1333 EKTKHFQLSVL 1343
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/150 (29%), Positives = 63/150 (42%), Gaps = 19/150 (12%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
I+ QL+D G + C+ + + RN L V VPP + Q + GS V L
Sbjct: 2180 ISKVQLADAGIFTCVAASPAGVADRNFT---LQVQVPPVLEPVEFQNDVVVVRGSLVELP 2236
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG-TVTIRNISALSSGLYQCVASNAIGT 223
C + G+P P W K P +Q QG ++ + + A SG Y CVA + G
Sbjct: 2237 CEAR-GVPLPLVSWMKDGE-----PLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGE 2290
Query: 224 STCLLDLQVISP-------QPRNIGLIAGA 246
+ L V+ P QP + L GA
Sbjct: 2291 ARRHFQLTVMEPPHIEDSGQPTELSLTPGA 2320
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 13/139 (9%)
Query: 113 SDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIP 172
+D+G Y C N V TV S P + + +L C ++ G+P
Sbjct: 2454 ADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAV---NVSVNQTALLPCQAD-GVP 2509
Query: 173 RPTYLWEKLDNTLKLPPTATQDQV--QGTVTIRNISALSSGLYQCVASNAIGTSTCLLDL 230
P W K + + L P + + ++ +G++ I+ + A +G Y C+ASN+ G+ DL
Sbjct: 2510 APLVSWRK--DRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDL 2567
Query: 231 QV-----ISPQPRNIGLIA 244
+V I+P P N+ L A
Sbjct: 2568 RVLEPPAIAPSPSNLTLTA 2586
Score = 45.4 bits (106), Expect = 1e-04
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSA-----PHCQIQGSQDIG 158
S+ + Q + TG Y C+ NL GR L+VLVPP P I + +
Sbjct: 1122 SLHVERAQAAHTGRYSCVAENL---AGRAERKFELSVLVPPELIGDLDPLTNITAA--LH 1176
Query: 159 SDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG-TVTIRNISALSSGLYQCVA 217
S + LLC + GIP P W + + + P T G + + SGLY C+A
Sbjct: 1177 SPLTLLCEAM-GIPPPAIRWFRGEEPVS-PGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1234
Query: 218 SNAIGTSTCLLDLQVISP 235
SN G + ++V+ P
Sbjct: 1235 SNEAGEARRNFSVEVLVP 1252
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 4/129 (3%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I L D G Y C NL R + L VLVPP+ + + + V L C
Sbjct: 661 IEKVDLRDEGIYTCAATNLAGESKREV---ALKVLVPPNIEPGPVNKAVLENASVTLECL 717
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
+ G+P P W K + T + I +G Y+CVASN G++
Sbjct: 718 A-SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTEL 776
Query: 227 LLDLQVISP 235
L+V P
Sbjct: 777 RYGLRVNVP 785
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Query: 116 GTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPT 175
G Y C N + +++ +T V P + + + +LL GIPRPT
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVV----RAVAEEEVLLPCEASGIPRPT 2787
Query: 176 YLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTS 224
W+K + +TQ G + I + S +G Y C+A N+ G++
Sbjct: 2788 ITWQK-EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSA 2835
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 3/129 (2%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
++ +++D +Y C+ N G + L V VPP ++ I + + L
Sbjct: 1712 VSTAEVADAASYMCVAENQ---AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPC 1768
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
P P W K L L T+ + SG+Y C A NA G
Sbjct: 1769 DVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 1828
Query: 227 LLDLQVISP 235
L+ L V+ P
Sbjct: 1829 LVQLSVLVP 1837
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 12/151 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
++ Q + GTY C+ N ++ V VLV P + + G +V L
Sbjct: 1991 LSRLQPAQAGTYTCVAENTQAEARKDFVVA---VLVAPRIRSSGVAREHHVLEGQEVRLD 2047
Query: 165 CSSEEGIPRPTYLWEKLDNTL--KLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
C ++ G P P W K + L + P G++ ++ + A +G Y CVA N G
Sbjct: 2048 CEAD-GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2106
Query: 223 TSTCLLDLQVISPQPRNIGLIAGAIGTGAVI 253
L + V+ P + GA G+G ++
Sbjct: 2107 EDARLHTVNVLVPPT----IKQGADGSGTLV 2133
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 105 IFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILL 164
+ + N + D GTY C N R + LT+LV P S +G + L
Sbjct: 2902 LLVKNLEGQDAGTYTCTAENAVGRARRRV---HLTILVLPVFTTLPGDRSLRLGDRLWLR 2958
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN--ISALSSGLYQCVASNAIG 222
C++ G P P W D P T + G T++ +S SG Y C A N +G
Sbjct: 2959 CAA-RGSPTPRIGWTVNDR----PVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 3013
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/157 (26%), Positives = 62/157 (39%), Gaps = 22/157 (14%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD--------IG 158
+ Q SD G Y C +N + T L V VPP+ I+G+ G
Sbjct: 369 LGRAQSSDAGVYTCKASNAVGAAEK---ATRLDVYVPPT-----IEGAGGRPYVVKAVAG 420
Query: 159 SDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVAS 218
V L C + G P PT W + + + + + + SSGLY CVAS
Sbjct: 421 RPVALECVAR-GHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 479
Query: 219 NAIGTSTCLLDLQV-ISPQPRNIGLIAGAIGTGAVII 254
+ G + ++V + PQ L+A +G I+
Sbjct: 480 SPAGEAVLQYSVEVQVPPQL----LVAEGLGQVTTIV 512
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 32/153 (20%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I TQ+SD+G Y C+ N + G + + + VPP Q D + +L
Sbjct: 1506 IQPTQVSDSGRYLCVATN---VAGEDDQDFNVLIQVPP-----MFQKVGDFSAAFEILSR 1557
Query: 167 SEEG------------------------IPRPTYLWEKLDNTLKLPPTATQDQVQGTVTI 202
EE IP P W + D L + Q + I
Sbjct: 1558 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQI 1617
Query: 203 RNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
+ A ++G Y C ASN +G +L V++P
Sbjct: 1618 PLVRAENAGRYSCKASNEVGEDWLHYELLVLTP 1650
Score = 38.9 bits (89), Expect = 0.009
Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 13/138 (9%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGS---- 159
S+ + + SD G Y C+ +N G + + + VLVPP+ QG+ G+
Sbjct: 2083 SLVLKGLRASDAGAYTCVAHNP---AGEDARLHTVNVLVPPTIK----QGADGSGTLVSR 2135
Query: 160 --DVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
+++ + G P W K L L T+ I + +G++ CVA
Sbjct: 2136 PGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA 2195
Query: 218 SNAIGTSTCLLDLQVISP 235
++ G + LQV P
Sbjct: 2196 ASPAGVADRNFTLQVQVP 2213
Score = 35.0 bits (79), Expect = 0.13
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 9/117 (7%)
Query: 150 QIQGSQDIGSDVILLCSS--EEGIPRPTYLWEKLDNTLKL---PPTATQDQVQGTVTIRN 204
+I+G D+ V L G P+P W K ++ L P A ++ G++ + +
Sbjct: 6 EIKGLGDVALTVGLEAGGCGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEE--GSLFLAS 63
Query: 205 ISALSSGLYQCVASNAIGTSTCLLDLQV-ISPQPRNIGLIAGAIG-TGAVIIIFCIA 259
+S SG Y+C A+N +G+++ L V + P R G A G G + + C A
Sbjct: 64 VSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDA 120
Score = 34.3 bits (77), Expect = 0.22
Identities = 56/260 (21%), Positives = 86/260 (33%), Gaps = 55/260 (21%)
Query: 19 VAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQG 78
V L V+E G + GQP LPC + S + W L N E++ Q
Sbjct: 495 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVP---TIQW----LQNGRPAEELAGVQ- 546
Query: 79 GQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGL 138
V GT ++ I++ +L +G + C N G + V+
Sbjct: 547 -------------VASQGT------TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 587
Query: 139 TVLVPP--SAPHCQIQGSQDIGSDVILLCSSE--------------EGIPRPTYLWEK-- 180
P P Q + S C EG P LW +
Sbjct: 588 GEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPT 647
Query: 181 -LDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRN 239
+ LPP + I + G+Y C A+N G S + L+V+ P
Sbjct: 648 GIPVAYSLPPP---------LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE 698
Query: 240 IGLIAGAIGTGAVIIIFCIA 259
G + A+ A + + C+A
Sbjct: 699 PGPVNKAVLENASVTLECLA 718
Score = 33.5 bits (75), Expect = 0.38
Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 35/206 (16%)
Query: 29 PGSIQVARGQPAVLPCTFTTSAALINLNVIWMV--TPLSNANQPEQVILYQGGQMFDGAP 86
PG + V P L C T + + ++W+ P+S A P G Q+F G
Sbjct: 795 PGPVLV--NTPVRLTCNATGAPSP---TLMWLKDGNPVSPAGTP-------GLQVFPG-- 840
Query: 87 RFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSA 146
GRV + + + + SD+G Y C+ + +G V L V +PPS
Sbjct: 841 ---GRV------------LTLASARASDSGRYSCVA--VSAVGEDRQDVV-LQVHMPPSI 882
Query: 147 PHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNIS 206
++ S V L C S +P P W K L+ P + + +
Sbjct: 883 LGEELNVSVVANESVALECQSH-AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRAD 941
Query: 207 ALSSGLYQCVASNAIGTSTCLLDLQV 232
+G Y C A N G S +L V
Sbjct: 942 VWDAGHYTCEALNQAGRSEKHYNLNV 967
Score = 31.2 bits (69), Expect = 1.9
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 113 SDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD--IGSDVILLCSSEEG 170
+ +G Y C+ ++ G + + V VPP + G +G + L C + G
Sbjct: 469 ASSGLYSCVASSP---AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQAS-G 524
Query: 171 IPRPTYLWEKLDNTLKLPPTA-TQDQVQGTVT-IRNISALSSGLYQCVASNAIGTSTCLL 228
P PT W L N A Q QGT I ++ SGL+ C A+N GT+ +
Sbjct: 525 SPVPTIQW--LQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEV 582
Query: 229 DLQV 232
++ V
Sbjct: 583 EVSV 586
Score = 30.8 bits (68), Expect = 2.5
Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 16/121 (13%)
Query: 143 PPSAPHCQIQGS-QDI----GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ 197
PP+ P G+ Q++ G+DV L C + G+P P W K + + P QVQ
Sbjct: 212 PPAPPSVLGAGAAQEVLGLAGADVELQCWTS-GVPTPQVEWTK--DRQPVLPGGPHLQVQ 268
Query: 198 GTVTIRNISAL---SSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVII 254
+ I+ G YQCVA + G L+V +P I G+ TG V +
Sbjct: 269 EDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPP-----TIWGSNETGEVAV 323
Query: 255 I 255
+
Sbjct: 324 M 324
Score = 30.0 bits (66), Expect = 4.2
Identities = 32/144 (22%), Positives = 57/144 (39%), Gaps = 21/144 (14%)
Query: 103 VSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD------ 156
V + + LS G Y C+ N G L+VL+ P+ + G++D
Sbjct: 1308 VLLQVLQANLSSAGHYSCIAANAV---GEKTKHFQLSVLLAPTI----LGGAEDSADEEV 1360
Query: 157 ---IGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGT--VTIRNISALSSG 211
+ + + L+C + P P W K + + + GT + I N +G
Sbjct: 1361 TVTVNNPISLICEAL-AFPSPNITWMK--DGAPFEASRNIQLLPGTHGLQILNAQKEDAG 1417
Query: 212 LYQCVASNAIGTSTCLLDLQVISP 235
Y CV +N +G + ++V+ P
Sbjct: 1418 QYTCVVTNELGEAVKNYHVEVLIP 1441
Score = 29.3 bits (64), Expect = 7.2
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPH--CQIQGSQDIGSDV 161
S+F+ + +D+G Y+C N ++G + L V VPPS + S G +
Sbjct: 58 SLFLASVSPADSGDYECQATN--EVGSTSRRAK-LVVYVPPSIREDGRKANVSGMAGQSL 114
Query: 162 ILLCSSEEGIPRPTYLWEK 180
L C + G P P +W K
Sbjct: 115 TLECDA-NGFPVPEIVWLK 132
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 58.5 bits (140), Expect = 1e-08
Identities = 45/150 (30%), Positives = 69/150 (46%), Gaps = 13/150 (8%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI---- 157
N S+ I+ T+ D G YQCL N + + + +LV SAP Q++ QD+
Sbjct: 4270 NGSLTIHRTERDDAGRYQCLAENEMGVAKK------VVILVLQSAPVFQVE-PQDMTVRS 4322
Query: 158 GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
G DV L C + G P PT W + L+ + G++ + N+ +G Y CVA
Sbjct: 4323 GDDVALRCQAT-GEPTPTIEWLQAGQPLRAS-RRLRTLPDGSLWLENVETGDAGTYDCVA 4380
Query: 218 SNAIGTSTCLLDLQVISPQPRNIGLIAGAI 247
N +G++T L V + G + G I
Sbjct: 4381 HNLLGSATARAFLVVRGEPQGSWGSMTGVI 4410
Score = 53.9 bits (128), Expect = 3e-07
Identities = 43/132 (32%), Positives = 61/132 (46%), Gaps = 7/132 (5%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAP-HCQIQGSQDIGSDVILLC 165
I QLSD G+Y+C+ +N + G GL V VPP + G + + V L C
Sbjct: 1943 IEQAQLSDAGSYRCVASN---VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 1999
Query: 166 SSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG--TVTIRNISALSSGLYQCVASNAIGT 223
++ G P PT +W K N + T G +T+ + A SG Y CVA +A+G
Sbjct: 2000 NAT-GAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGE 2058
Query: 224 STCLLDLQVISP 235
+ LQV P
Sbjct: 2059 DRQDVVLQVHMP 2070
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 9/116 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQG-SQDIGSDVILLC 165
I Q+SD G Y C V+N + G + LTV VPP+ + + + SQ GS ++L C
Sbjct: 3090 IQEAQVSDKGLYSCKVSN---VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 3146
Query: 166 SSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ--GTVTIRNISALSSGLYQCVASN 219
G+P PT W L + + + +A V G + + + +G Y CVA N
Sbjct: 3147 DVS-GVPAPTVTW--LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 3199
Score = 52.4 bits (124), Expect = 8e-07
Identities = 51/209 (24%), Positives = 76/209 (36%), Gaps = 31/209 (14%)
Query: 24 EVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFD 83
+++ S +++V GQP LPC L PE+ L G +
Sbjct: 886 QIASSAPTVRVLEGQPVSLPCIVLAGRPL-----------------PERHWLKDGRPLPP 928
Query: 84 GAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVP 143
G+ G S+ ++ G Y C+ N R++ L V VP
Sbjct: 929 GSRHSIRADG----------SLHLDRALQEHAGRYSCVATNTAGSQHRDVE---LVVQVP 975
Query: 144 PSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIR 203
P + G L C + G+P PT W K N L +GT+ I
Sbjct: 976 PRIHPTATHHITNEGVPASLPCVAS-GVPAPTITWTKETNALTSRGPHYNVSKEGTLLIA 1034
Query: 204 NISALSSGLYQCVASNAIGTSTCLLDLQV 232
SA +G Y C A+N +G S+ + L V
Sbjct: 1035 QPSAQDAGAYVCTATNTVGFSSQEMRLSV 1063
Score = 52.4 bits (124), Expect = 8e-07
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 114 DTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPR 173
D G Y C+ N G +G T L V VPP + S GS L C + G P
Sbjct: 4011 DAGNYLCIAKNS---AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKAR-GSPE 4066
Query: 174 PTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVI 233
P W+K + Q G + ++N+ +G Y C A NA+G + + L ++
Sbjct: 4067 PNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL 4126
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/225 (24%), Positives = 96/225 (42%), Gaps = 34/225 (15%)
Query: 25 VSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDG 84
++ SP ++ + PA+LPC + S + V+W ++ GQ D
Sbjct: 3766 IAPSPSNLTLTAHTPALLPCEASGSPKPL---VVW----------------WKDGQKLD- 3805
Query: 85 APRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPP 144
F + G +P+ + + Q D+ ++C+V+N ++G + + +TV VPP
Sbjct: 3806 ---FRLQQGAYRLLPSNALLLTAPGPQ--DSAQFECVVSN--EVGEAH-RLYQVTVHVPP 3857
Query: 145 SAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN 204
+ Q + + + V+L C S GIP PT W K L + + G + I
Sbjct: 3858 TIADDQTDFTVTMMAPVVLTCHST-GIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQ 3916
Query: 205 ISALSSGLYQCVASNAIGTS--TCLLDLQ---VISPQPRNIGLIA 244
+ +G Y C A N+ G + L +Q V+ P P + +A
Sbjct: 3917 ALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 3961
Score = 49.3 bits (116), Expect = 7e-06
Identities = 60/232 (25%), Positives = 93/232 (40%), Gaps = 46/232 (19%)
Query: 31 SIQVARGQPAVLPCTFTTSAALINLNVI--WMVTPLSNANQPEQVILYQGGQMFDGAPRF 88
++ V+ G+ AVL C A NL + W V P S
Sbjct: 525 NVTVSPGETAVLSCRVLGEAPY-NLTWVRDWRVLPAST---------------------- 561
Query: 89 HGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTV-LVPPSAP 147
GRV ++S+ I+ +D G YQC+ +N GVT +V L+ AP
Sbjct: 562 -GRVA-----QLADLSLEISGIIPTDGGRYQCVASNAN-------GVTRASVWLLVREAP 608
Query: 148 HCQIQGSQDI---GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN 204
I S G +V + CS+ G P P W + L+ D QGT+ I+
Sbjct: 609 QVSIHTSSQHFSQGVEVKVSCSAS-GYPTPHISWSRESQALQEDSRIHVD-AQGTLIIQG 666
Query: 205 ISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNI--GLIAGAIGTGAVII 254
++ +G Y C A+N +GT + L P + ++ A+G AV++
Sbjct: 667 VAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLV 718
Score = 48.9 bits (115), Expect = 9e-06
Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
+ TQ D+G Y CL +N RN V VLVPPS + ++ + G L+
Sbjct: 2410 MTQTQEQDSGLYSCLASNEAGEARRNFSVE---VLVPPSIENEDLEEVIKVLDGQTAHLM 2466
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPT--ATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
C+ G P+P W K L + D V V N+S S+G Y C+A+NA+G
Sbjct: 2467 CNVT-GHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLS--SAGHYSCIAANAVG 2523
Query: 223 TSTCLLDLQVI 233
T L V+
Sbjct: 2524 EKTKHFQLSVL 2534
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/150 (29%), Positives = 63/150 (42%), Gaps = 19/150 (12%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
I+ QL+D G + C+ + + RN L V VPP + Q + GS V L
Sbjct: 3371 ISKVQLADAGIFTCVAASPAGVADRNFT---LQVQVPPVLEPVEFQNDVVVVRGSLVELP 3427
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG-TVTIRNISALSSGLYQCVASNAIGT 223
C + G+P P W K P +Q QG ++ + + A SG Y CVA + G
Sbjct: 3428 CEAR-GVPLPLVSWMKDGE-----PLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGE 3481
Query: 224 STCLLDLQVISP-------QPRNIGLIAGA 246
+ L V+ P QP + L GA
Sbjct: 3482 ARRHFQLTVMEPPHIEDSGQPTELSLTPGA 3511
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 13/139 (9%)
Query: 113 SDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIP 172
+D+G Y C N V TV S P + + +L C ++ G+P
Sbjct: 3645 ADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAV---NVSVNQTALLPCQAD-GVP 3700
Query: 173 RPTYLWEKLDNTLKLPPTATQDQV--QGTVTIRNISALSSGLYQCVASNAIGTSTCLLDL 230
P W K + + L P + + ++ +G++ I+ + A +G Y C+ASN+ G+ DL
Sbjct: 3701 APLVSWRK--DRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDL 3758
Query: 231 QV-----ISPQPRNIGLIA 244
+V I+P P N+ L A
Sbjct: 3759 RVLEPPAIAPSPSNLTLTA 3777
Score = 45.4 bits (106), Expect = 1e-04
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSA-----PHCQIQGSQDIG 158
S+ + Q + TG Y C+ NL GR L+VLVPP P I + +
Sbjct: 2313 SLHVERAQAAHTGRYSCVAENL---AGRAERKFELSVLVPPELIGDLDPLTNITAA--LH 2367
Query: 159 SDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG-TVTIRNISALSSGLYQCVA 217
S + LLC + GIP P W + + + P T G + + SGLY C+A
Sbjct: 2368 SPLTLLCEAM-GIPPPAIRWFRGEEPVS-PGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 2425
Query: 218 SNAIGTSTCLLDLQVISP 235
SN G + ++V+ P
Sbjct: 2426 SNEAGEARRNFSVEVLVP 2443
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 4/129 (3%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I L D G Y C NL R + L VLVPP+ + + + V L C
Sbjct: 1852 IEKVDLRDEGIYTCAATNLAGESKREV---ALKVLVPPNIEPGPVNKAVLENASVTLECL 1908
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
+ G+P P W K + T + I +G Y+CVASN G++
Sbjct: 1909 A-SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTEL 1967
Query: 227 LLDLQVISP 235
L+V P
Sbjct: 1968 RYGLRVNVP 1976
Score = 43.9 bits (102), Expect = 3e-04
Identities = 43/163 (26%), Positives = 72/163 (44%), Gaps = 13/163 (7%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD--IGSDV 161
S+ + SD G Y+C +N + + L VL PP + G + G +
Sbjct: 1168 SVHFAAIRTSDAGRYRCEASNSAGVDAWEVE---LRVLEPPHWGADETSGLLERVAGENA 1224
Query: 162 ILLCSSEEGIPRPTYLWEKLDNTLKL---PPTATQDQVQGTVTIRNISALSSGLYQCVAS 218
L C + G P+P W K ++ L P A ++ G++ + ++S SG Y+C A+
Sbjct: 1225 SLPCPAR-GTPKPQVTWRKGPSSEPLHGQPGVAVLEE--GSLFLASVSPADSGDYECQAT 1281
Query: 219 NAIGTSTCLLDLQV-ISPQPRNIGLIAGAIG-TGAVIIIFCIA 259
N +G+++ L V + P R G A G G + + C A
Sbjct: 1282 NEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDA 1324
Score = 42.0 bits (97), Expect = 0.001
Identities = 38/132 (28%), Positives = 57/132 (43%), Gaps = 10/132 (7%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVIL 163
S+ + Q+ D+G Y+C +N P + V G V VPP +G + L
Sbjct: 1083 SLRLAQVQVGDSGHYECTASN-PAGSASHRYVLG--VQVPPQVQPGPRVLKVLVGEALDL 1139
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT 223
C +E G P P W K L+ QG+V I +G Y+C ASN+ G
Sbjct: 1140 NCVAE-GNPEPQLSWSKDGVVLQ------GRGPQGSVHFAAIRTSDAGRYRCEASNSAGV 1192
Query: 224 STCLLDLQVISP 235
++L+V+ P
Sbjct: 1193 DAWEVELRVLEP 1204
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Query: 116 GTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPT 175
G Y C N + +++ +T V P + + + +LL GIPRPT
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVV----RAVAEEEVLLPCEASGIPRPT 3978
Query: 176 YLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTS 224
W+K + +TQ G + I + S +G Y C+A N+ G++
Sbjct: 3979 ITWQK-EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSA 4026
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 3/129 (2%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
++ +++D +Y C+ N G + L V VPP ++ I + + L
Sbjct: 2903 VSTAEVADAASYMCVAENQ---AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPC 2959
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
P P W K L L T+ + SG+Y C A NA G
Sbjct: 2960 DVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 3019
Query: 227 LLDLQVISP 235
L+ L V+ P
Sbjct: 3020 LVQLSVLVP 3028
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 12/151 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
++ Q + GTY C+ N ++ V VLV P + + G +V L
Sbjct: 3182 LSRLQPAQAGTYTCVAENTQAEARKDFVVA---VLVAPRIRSSGVAREHHVLEGQEVRLD 3238
Query: 165 CSSEEGIPRPTYLWEKLDNTL--KLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
C ++ G P P W K + L + P G++ ++ + A +G Y CVA N G
Sbjct: 3239 CEAD-GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 3297
Query: 223 TSTCLLDLQVISPQPRNIGLIAGAIGTGAVI 253
L + V+ P + GA G+G ++
Sbjct: 3298 EDARLHTVNVLVPPT----IKQGADGSGTLV 3324
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 105 IFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILL 164
+ + N + D GTY C N R + LT+LV P S +G + L
Sbjct: 4093 LLVKNLEGQDAGTYTCTAENAVGRARRRV---HLTILVLPVFTTLPGDRSLRLGDRLWLR 4149
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN--ISALSSGLYQCVASNAIG 222
C++ G P P W D P T + G T++ +S SG Y C A N +G
Sbjct: 4150 CAA-RGSPTPRIGWTVNDR----PVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 4204
Score = 39.7 bits (91), Expect = 0.005
Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 20/159 (12%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI----GS 159
S+ Q D+G Y C N R+ L VL PPS +Q++ G+
Sbjct: 1370 SLHFPRIQEGDSGLYSCRAENQAGTAQRDFH---LLVLTPPSV--LGAGAAQEVLGLAGA 1424
Query: 160 DVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISAL---SSGLYQCV 216
DV L C + G+P P W K + + P QVQ + I+ G YQCV
Sbjct: 1425 DVELQCWTS-GVPTPQVEWTK--DRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCV 1481
Query: 217 ASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIII 255
A + G L+V +P I G+ TG V ++
Sbjct: 1482 AFSPAGQQARDFQLRVHAPP-----TIWGSNETGEVAVM 1515
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/157 (26%), Positives = 62/157 (39%), Gaps = 22/157 (14%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD--------IG 158
+ Q SD G Y C +N + T L V VPP+ I+G+ G
Sbjct: 1560 LGRAQSSDAGVYTCKASNAVGAAEK---ATRLDVYVPPT-----IEGAGGRPYVVKAVAG 1611
Query: 159 SDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVAS 218
V L C + G P PT W + + + + + + SSGLY CVAS
Sbjct: 1612 RPVALECVAR-GHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 1670
Query: 219 NAIGTSTCLLDLQV-ISPQPRNIGLIAGAIGTGAVII 254
+ G + ++V + PQ L+A +G I+
Sbjct: 1671 SPAGEAVLQYSVEVQVPPQL----LVAEGLGQVTTIV 1703
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 32/153 (20%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I TQ+SD+G Y C+ N + G + + + VPP Q D + +L
Sbjct: 2697 IQPTQVSDSGRYLCVATN---VAGEDDQDFNVLIQVPP-----MFQKVGDFSAAFEILSR 2748
Query: 167 SEEG------------------------IPRPTYLWEKLDNTLKLPPTATQDQVQGTVTI 202
EE IP P W + D L + Q + I
Sbjct: 2749 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQI 2808
Query: 203 RNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
+ A ++G Y C ASN +G +L V++P
Sbjct: 2809 PLVRAENAGRYSCKASNEVGEDWLHYELLVLTP 2841
Score = 38.9 bits (89), Expect = 0.009
Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 13/138 (9%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGS---- 159
S+ + + SD G Y C+ +N G + + + VLVPP+ QG+ G+
Sbjct: 3274 SLVLKGLRASDAGAYTCVAHNP---AGEDARLHTVNVLVPPTIK----QGADGSGTLVSR 3326
Query: 160 --DVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
+++ + G P W K L L T+ I + +G++ CVA
Sbjct: 3327 PGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA 3386
Query: 218 SNAIGTSTCLLDLQVISP 235
++ G + LQV P
Sbjct: 3387 ASPAGVADRNFTLQVQVP 3404
Score = 37.4 bits (85), Expect = 0.027
Identities = 55/228 (24%), Positives = 82/228 (35%), Gaps = 51/228 (22%)
Query: 27 ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNA--NQPEQVILYQGGQMFDG 84
E+ G ++ G+ A LPC + V W P S QP +L +G
Sbjct: 1211 ETSGLLERVAGENASLPCP---ARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG------ 1261
Query: 85 APRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPP 144
S+F+ + +D+G Y+C N ++G + L V VPP
Sbjct: 1262 -------------------SLFLASVSPADSGDYECQATN--EVGSTSRRAK-LVVYVPP 1299
Query: 145 SAPHC--QIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPP-------TATQDQ 195
S + S G + L C + G P P +W K + +P Q
Sbjct: 1300 SIREDGRKANVSGMAGQSLTLECDAN-GFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQ 1358
Query: 196 VQG--------TVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
V G ++ I SGLY C A N GT+ L V++P
Sbjct: 1359 VGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTP 1406
Score = 34.3 bits (77), Expect = 0.22
Identities = 56/260 (21%), Positives = 86/260 (33%), Gaps = 55/260 (21%)
Query: 19 VAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQG 78
V L V+E G + GQP LPC + S + W L N E++ Q
Sbjct: 1686 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVP---TIQW----LQNGRPAEELAGVQ- 1737
Query: 79 GQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGL 138
V GT ++ I++ +L +G + C N G + V+
Sbjct: 1738 -------------VASQGT------TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 1778
Query: 139 TVLVPP--SAPHCQIQGSQDIGSDVILLCSSE--------------EGIPRPTYLWEK-- 180
P P Q + S C EG P LW +
Sbjct: 1779 GEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPT 1838
Query: 181 -LDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRN 239
+ LPP + I + G+Y C A+N G S + L+V+ P
Sbjct: 1839 GIPVAYSLPPP---------LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE 1889
Query: 240 IGLIAGAIGTGAVIIIFCIA 259
G + A+ A + + C+A
Sbjct: 1890 PGPVNKAVLENASVTLECLA 1909
Score = 33.9 bits (76), Expect = 0.29
Identities = 49/219 (22%), Positives = 79/219 (36%), Gaps = 37/219 (16%)
Query: 24 EVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFD 83
+++E P + V G+ A+L C T +P + ++ G D
Sbjct: 787 QLTELPRDVTVELGRSALLACRAT--------------------GRPPPTVTWRRG---D 823
Query: 84 GAP---RFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNL---PDIGGRNIGVTG 137
G P R G P + V +F + D Y C N+ R I
Sbjct: 824 GQPLGLRLGAGRGSRSRQPDSGV-LFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGH 882
Query: 138 LTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQD-QV 196
+ SAP ++ Q + I+L G P P W L + LPP + +
Sbjct: 883 APPQIASSAPTVRVLEGQPVSLPCIVLA----GRPLPERHW--LKDGRPLPPGSRHSIRA 936
Query: 197 QGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
G++ + +G Y CVA+N G+ ++L V P
Sbjct: 937 DGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVP 975
Score = 33.1 bits (74), Expect = 0.50
Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 35/206 (16%)
Query: 29 PGSIQVARGQPAVLPCTFTTSAALINLNVIWMV--TPLSNANQPEQVILYQGGQMFDGAP 86
PG + V P L C T + + ++W+ P+S A P G Q+F G
Sbjct: 1986 PGPVLV--NTPVRLTCNATGAPSP---TLMWLKDGNPVSPAGTP-------GLQVFPG-- 2031
Query: 87 RFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSA 146
GRV + + + + SD+G Y C+ + +G V L V +PPS
Sbjct: 2032 ---GRV------------LTLASARASDSGRYSCVA--VSAVGEDRQDVV-LQVHMPPSI 2073
Query: 147 PHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNIS 206
++ S V L C S +P P W K L+ P + + +
Sbjct: 2074 LGEELNVSVVANESVALECQSH-AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRAD 2132
Query: 207 ALSSGLYQCVASNAIGTSTCLLDLQV 232
+G Y C A N G S +L V
Sbjct: 2133 VWDAGHYTCEALNQAGHSEKHYNLNV 2158
Score = 31.2 bits (69), Expect = 1.9
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 113 SDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD--IGSDVILLCSSEEG 170
+ +G Y C+ ++ G + + V VPP + G +G + L C + G
Sbjct: 1660 ASSGLYSCVASSP---AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQAS-G 1715
Query: 171 IPRPTYLWEKLDNTLKLPPTA-TQDQVQGTVT-IRNISALSSGLYQCVASNAIGTSTCLL 228
P PT W L N A Q QGT I ++ SGL+ C A+N GT+ +
Sbjct: 1716 SPVPTIQW--LQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEV 1773
Query: 229 DLQV 232
++ V
Sbjct: 1774 EVSV 1777
Score = 30.0 bits (66), Expect = 4.2
Identities = 32/144 (22%), Positives = 57/144 (39%), Gaps = 21/144 (14%)
Query: 103 VSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD------ 156
V + + LS G Y C+ N G L+VL+ P+ + G++D
Sbjct: 2499 VLLQVLQANLSSAGHYSCIAANAV---GEKTKHFQLSVLLAPTI----LGGAEDSADEEV 2551
Query: 157 ---IGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGT--VTIRNISALSSG 211
+ + + L+C + P P W K + + + GT + I N +G
Sbjct: 2552 TVTVNNPISLICEAL-AFPSPNITWMK--DGAPFEASRNIQLLPGTHGLQILNAQKEDAG 2608
Query: 212 LYQCVASNAIGTSTCLLDLQVISP 235
Y CV +N +G + ++V+ P
Sbjct: 2609 QYTCVVTNELGEAVKNYHVEVLIP 2632
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 13/150 (8%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI---- 157
N S+ I T+ D G YQCL N + + + +LV SAP Q++ QD+
Sbjct: 2988 NGSLTIRRTERDDAGRYQCLAENEMGVAKK------VVILVLQSAPVFQVE-PQDMTVRS 3040
Query: 158 GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
G DV L C + G P PT W + L+ + G++ + N+ +G Y CVA
Sbjct: 3041 GDDVALRCQAT-GEPTPTIEWLQAGQPLRAS-RRLRTLPDGSLWLENVETGDAGTYDCVA 3098
Query: 218 SNAIGTSTCLLDLQVISPQPRNIGLIAGAI 247
N +G++T L V + G + G I
Sbjct: 3099 HNLLGSATARAFLVVRGEPQGSWGSMTGVI 3128
Score = 53.9 bits (128), Expect = 3e-07
Identities = 43/132 (32%), Positives = 61/132 (46%), Gaps = 7/132 (5%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAP-HCQIQGSQDIGSDVILLC 165
I QLSD G+Y+C+ +N + G GL V VPP + G + + V L C
Sbjct: 661 IEQAQLSDAGSYRCVASN---VAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTC 717
Query: 166 SSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG--TVTIRNISALSSGLYQCVASNAIGT 223
++ G P PT +W K N + T G +T+ + A SG Y CVA +A+G
Sbjct: 718 NAT-GAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGE 776
Query: 224 STCLLDLQVISP 235
+ LQV P
Sbjct: 777 DRQDVVLQVHMP 788
Score = 53.9 bits (128), Expect = 3e-07
Identities = 37/116 (31%), Positives = 56/116 (48%), Gaps = 9/116 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQG-SQDIGSDVILLC 165
I Q+SD G Y C V+N + G + LTV VPP+ + + + SQ GS ++L C
Sbjct: 1808 IQEAQVSDKGLYSCKVSN---VAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC 1864
Query: 166 SSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ--GTVTIRNISALSSGLYQCVASN 219
G+P PT W L + + + +A V G + + + +G Y CVA N
Sbjct: 1865 DVS-GVPAPTVTW--LKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAEN 1917
Score = 52.4 bits (124), Expect = 8e-07
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 4/120 (3%)
Query: 114 DTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPR 173
D G Y C+ N G +G T L V VPP + S GS L C + G P
Sbjct: 2729 DAGNYLCIAKNS---AGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKAR-GSPE 2784
Query: 174 PTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVI 233
P W+K + Q G + ++N+ +G Y C A NA+G + + L ++
Sbjct: 2785 PNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL 2844
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/225 (24%), Positives = 96/225 (42%), Gaps = 34/225 (15%)
Query: 25 VSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDG 84
++ SP ++ + PA+LPC + S + V+W ++ GQ D
Sbjct: 2484 IAPSPSNLTLTAHTPALLPCEASGSPKPL---VVW----------------WKDGQKLD- 2523
Query: 85 APRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPP 144
F + G +P+ + + Q D+ ++C+V+N ++G + + +TV VPP
Sbjct: 2524 ---FRLQQGAYRLLPSNALLLTAPGPQ--DSAQFECVVSN--EVGEAH-RLYQVTVHVPP 2575
Query: 145 SAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN 204
+ Q + + + V+L C S GIP PT W K L + + G + I
Sbjct: 2576 TIADDQTDFTVTMMAPVVLTCHST-GIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQ 2634
Query: 205 ISALSSGLYQCVASNAIGTS--TCLLDLQ---VISPQPRNIGLIA 244
+ +G Y C A N+ G + L +Q V+ P P + +A
Sbjct: 2635 ALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 2679
Score = 48.9 bits (115), Expect = 9e-06
Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
+ TQ D+G Y CL +N RN V VLVPPS + ++ + G L+
Sbjct: 1128 MTQTQEQDSGLYSCLASNEAGEARRNFSVE---VLVPPSIENEDLEEVIKVLDGQTAHLM 1184
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPT--ATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
C+ G P+P W K L + D V V N+S S+G Y C+A+NA+G
Sbjct: 1185 CNVT-GHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLS--SAGHYSCIAANAVG 1241
Query: 223 TSTCLLDLQVI 233
T L V+
Sbjct: 1242 EKTKHFQLSVL 1252
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/150 (29%), Positives = 63/150 (42%), Gaps = 19/150 (12%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
I+ QL+D G + C+ + + RN L V VPP + Q + GS V L
Sbjct: 2089 ISKVQLADAGIFTCVAASPAGVADRNFT---LQVQVPPVLEPVEFQNDVVVVRGSLVELP 2145
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG-TVTIRNISALSSGLYQCVASNAIGT 223
C + G+P P W K P +Q QG ++ + + A SG Y CVA + G
Sbjct: 2146 CEAR-GVPLPLVSWMKDGE-----PLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGE 2199
Query: 224 STCLLDLQVISP-------QPRNIGLIAGA 246
+ L V+ P QP + L GA
Sbjct: 2200 ARRHFQLTVMEPPHIEDSGQPTELSLTPGA 2229
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 13/139 (9%)
Query: 113 SDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIP 172
+D+G Y C N V TV S P + + +L C ++ G+P
Sbjct: 2363 ADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAV---NVSVNQTALLPCQAD-GVP 2418
Query: 173 RPTYLWEKLDNTLKLPPTATQDQV--QGTVTIRNISALSSGLYQCVASNAIGTSTCLLDL 230
P W K + + L P + + ++ +G++ I+ + A +G Y C+ASN+ G+ DL
Sbjct: 2419 APLVSWRK--DRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDL 2476
Query: 231 QV-----ISPQPRNIGLIA 244
+V I+P P N+ L A
Sbjct: 2477 RVLEPPAIAPSPSNLTLTA 2495
Score = 45.4 bits (106), Expect = 1e-04
Identities = 41/138 (29%), Positives = 60/138 (43%), Gaps = 13/138 (9%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSA-----PHCQIQGSQDIG 158
S+ + Q + TG Y C+ NL GR L+VLVPP P I + +
Sbjct: 1031 SLHVERAQAAHTGRYSCVAENL---AGRAERKFELSVLVPPELIGDLDPLTNITAA--LH 1085
Query: 159 SDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG-TVTIRNISALSSGLYQCVA 217
S + LLC + GIP P W + + + P T G + + SGLY C+A
Sbjct: 1086 SPLTLLCEAM-GIPPPAIRWFRGEEPVS-PGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1143
Query: 218 SNAIGTSTCLLDLQVISP 235
SN G + ++V+ P
Sbjct: 1144 SNEAGEARRNFSVEVLVP 1161
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 4/129 (3%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I L D G Y C NL R + L VLVPP+ + + + V L C
Sbjct: 570 IEKVDLRDEGIYTCAATNLAGESKREV---ALKVLVPPNIEPGPVNKAVLENASVTLECL 626
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
+ G+P P W K + T + I +G Y+CVASN G++
Sbjct: 627 A-SGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTEL 685
Query: 227 LLDLQVISP 235
L+V P
Sbjct: 686 RYGLRVNVP 694
Score = 40.8 bits (94), Expect = 0.002
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 5/109 (4%)
Query: 116 GTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPT 175
G Y C N + +++ +T V P + + + +LL GIPRPT
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVV----RAVAEEEVLLPCEASGIPRPT 2696
Query: 176 YLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTS 224
W+K + +TQ G + I + S +G Y C+A N+ G++
Sbjct: 2697 ITWQK-EGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSA 2744
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/129 (24%), Positives = 48/129 (37%), Gaps = 3/129 (2%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
++ +++D +Y C+ N G + L V VPP ++ I + + L
Sbjct: 1621 VSTAEVADAASYMCVAENQ---AGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPC 1677
Query: 167 SEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTC 226
P P W K L L T+ + SG+Y C A NA G
Sbjct: 1678 DVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQK 1737
Query: 227 LLDLQVISP 235
L+ L V+ P
Sbjct: 1738 LVQLSVLVP 1746
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/151 (25%), Positives = 63/151 (41%), Gaps = 12/151 (7%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI--GSDVILL 164
++ Q + GTY C+ N ++ V VLV P + + G +V L
Sbjct: 1900 LSRLQPAQAGTYTCVAENTQAEARKDFVVA---VLVAPRIRSSGVAREHHVLEGQEVRLD 1956
Query: 165 CSSEEGIPRPTYLWEKLDNTL--KLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
C ++ G P P W K + L + P G++ ++ + A +G Y CVA N G
Sbjct: 1957 CEAD-GQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAG 2015
Query: 223 TSTCLLDLQVISPQPRNIGLIAGAIGTGAVI 253
L + V+ P + GA G+G ++
Sbjct: 2016 EDARLHTVNVLVPPT----IKQGADGSGTLV 2042
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/120 (28%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 105 IFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILL 164
+ + N + D GTY C N R + LT+LV P S +G + L
Sbjct: 2811 LLVKNLEGQDAGTYTCTAENAVGRARRRV---HLTILVLPVFTTLPGDRSLRLGDRLWLR 2867
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRN--ISALSSGLYQCVASNAIG 222
C++ G P P W D P T + G T++ +S SG Y C A N +G
Sbjct: 2868 CAA-RGSPTPRIGWTVNDR----PVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVG 2922
Score = 39.7 bits (91), Expect = 0.005
Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 20/159 (12%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI----GS 159
S+ Q D+G Y C N R+ L VL PPS +Q++ G+
Sbjct: 88 SLHFPRIQEGDSGLYSCRAENQAGTAQRDFH---LLVLTPPSV--LGAGAAQEVLGLAGA 142
Query: 160 DVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISAL---SSGLYQCV 216
DV L C + G+P P W K + + P QVQ + I+ G YQCV
Sbjct: 143 DVELQCWTS-GVPTPQVEWTK--DRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCV 199
Query: 217 ASNAIGTSTCLLDLQVISPQPRNIGLIAGAIGTGAVIII 255
A + G L+V +P I G+ TG V ++
Sbjct: 200 AFSPAGQQARDFQLRVHAPP-----TIWGSNETGEVAVM 233
Score = 39.7 bits (91), Expect = 0.005
Identities = 41/157 (26%), Positives = 62/157 (39%), Gaps = 22/157 (14%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD--------IG 158
+ Q SD G Y C +N + T L V VPP+ I+G+ G
Sbjct: 278 LGRAQSSDAGVYTCKASNAVGAAEK---ATRLDVYVPPT-----IEGAGGRPYVVKAVAG 329
Query: 159 SDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVAS 218
V L C + G P PT W + + + + + + SSGLY CVAS
Sbjct: 330 RPVALECVAR-GHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVAS 388
Query: 219 NAIGTSTCLLDLQV-ISPQPRNIGLIAGAIGTGAVII 254
+ G + ++V + PQ L+A +G I+
Sbjct: 389 SPAGEAVLQYSVEVQVPPQL----LVAEGLGQVTTIV 421
Score = 39.3 bits (90), Expect = 0.007
Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 32/153 (20%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCS 166
I TQ+SD+G Y C+ N + G + + + VPP Q D + +L
Sbjct: 1415 IQPTQVSDSGRYLCVATN---VAGEDDQDFNVLIQVPP-----MFQKVGDFSAAFEILSR 1466
Query: 167 SEEG------------------------IPRPTYLWEKLDNTLKLPPTATQDQVQGTVTI 202
EE IP P W + D L + Q + I
Sbjct: 1467 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQI 1526
Query: 203 RNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
+ A ++G Y C ASN +G +L V++P
Sbjct: 1527 PLVRAENAGRYSCKASNEVGEDWLHYELLVLTP 1559
Score = 38.9 bits (89), Expect = 0.009
Identities = 33/138 (23%), Positives = 56/138 (40%), Gaps = 13/138 (9%)
Query: 104 SIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGS---- 159
S+ + + SD G Y C+ +N G + + + VLVPP+ QG+ G+
Sbjct: 1992 SLVLKGLRASDAGAYTCVAHNP---AGEDARLHTVNVLVPPTIK----QGADGSGTLVSR 2044
Query: 160 --DVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
+++ + G P W K L L T+ I + +G++ CVA
Sbjct: 2045 PGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVA 2104
Query: 218 SNAIGTSTCLLDLQVISP 235
++ G + LQV P
Sbjct: 2105 ASPAGVADRNFTLQVQVP 2122
Score = 34.3 bits (77), Expect = 0.22
Identities = 56/260 (21%), Positives = 86/260 (33%), Gaps = 55/260 (21%)
Query: 19 VAASLEVSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQG 78
V L V+E G + GQP LPC + S + W L N E++ Q
Sbjct: 404 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVP---TIQW----LQNGRPAEELAGVQ- 455
Query: 79 GQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGL 138
V GT ++ I++ +L +G + C N G + V+
Sbjct: 456 -------------VASQGT------TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSVH 496
Query: 139 TVLVPP--SAPHCQIQGSQDIGSDVILLCSSE--------------EGIPRPTYLWEK-- 180
P P Q + S C EG P LW +
Sbjct: 497 GEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLWGEPT 556
Query: 181 -LDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRN 239
+ LPP + I + G+Y C A+N G S + L+V+ P
Sbjct: 557 GIPVAYSLPPP---------LQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIE 607
Query: 240 IGLIAGAIGTGAVIIIFCIA 259
G + A+ A + + C+A
Sbjct: 608 PGPVNKAVLENASVTLECLA 627
Score = 33.1 bits (74), Expect = 0.50
Identities = 51/206 (24%), Positives = 77/206 (37%), Gaps = 35/206 (16%)
Query: 29 PGSIQVARGQPAVLPCTFTTSAALINLNVIWMV--TPLSNANQPEQVILYQGGQMFDGAP 86
PG + V P L C T + + ++W+ P+S A P G Q+F G
Sbjct: 704 PGPVLV--NTPVRLTCNATGAPSP---TLMWLKDGNPVSPAGTP-------GLQVFPG-- 749
Query: 87 RFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSA 146
GRV + + + + SD+G Y C+ + +G V L V +PPS
Sbjct: 750 ---GRV------------LTLASARASDSGRYSCVA--VSAVGEDRQDVV-LQVHMPPSI 791
Query: 147 PHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNIS 206
++ S V L C S +P P W K L+ P + + +
Sbjct: 792 LGEELNVSVVANESVALECQSH-AMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRAD 850
Query: 207 ALSSGLYQCVASNAIGTSTCLLDLQV 232
+G Y C A N G S +L V
Sbjct: 851 VWDAGHYTCEALNQAGHSEKHYNLNV 876
Score = 31.2 bits (69), Expect = 1.9
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 113 SDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD--IGSDVILLCSSEEG 170
+ +G Y C+ ++ G + + V VPP + G +G + L C + G
Sbjct: 378 ASSGLYSCVASSP---AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQAS-G 433
Query: 171 IPRPTYLWEKLDNTLKLPPTA-TQDQVQGTVT-IRNISALSSGLYQCVASNAIGTSTCLL 228
P PT W L N A Q QGT I ++ SGL+ C A+N GT+ +
Sbjct: 434 SPVPTIQW--LQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEV 491
Query: 229 DLQV 232
++ V
Sbjct: 492 EVSV 495
Score = 30.0 bits (66), Expect = 4.2
Identities = 32/144 (22%), Positives = 57/144 (39%), Gaps = 21/144 (14%)
Query: 103 VSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQD------ 156
V + + LS G Y C+ N G L+VL+ P+ + G++D
Sbjct: 1217 VLLQVLQANLSSAGHYSCIAANAV---GEKTKHFQLSVLLAPTI----LGGAEDSADEEV 1269
Query: 157 ---IGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGT--VTIRNISALSSG 211
+ + + L+C + P P W K + + + GT + I N +G
Sbjct: 1270 TVTVNNPISLICEAL-AFPSPNITWMK--DGAPFEASRNIQLLPGTHGLQILNAQKEDAG 1326
Query: 212 LYQCVASNAIGTSTCLLDLQVISP 235
Y CV +N +G + ++V+ P
Sbjct: 1327 QYTCVVTNELGEAVKNYHVEVLIP 1350
>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
sapiens]
Length = 1386
Score = 58.2 bits (139), Expect = 1e-08
Identities = 63/224 (28%), Positives = 94/224 (41%), Gaps = 43/224 (19%)
Query: 21 ASLEVS-------ESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQV 73
ASLEV+ +SPG++ VA G+PAVL C V P + PE
Sbjct: 157 ASLEVAVLRDDFRQSPGNVVVAVGEPAVLEC----------------VPPRGH---PEPS 197
Query: 74 ILYQGGQMFDGA--PRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGR 131
+ ++ DGA GR+ G + +++T SD G Y C+ +N+ G R
Sbjct: 198 VSWRK----DGARLKEEEGRITIRGG------KLMMSHTLKSDAGMYVCVASNMA--GER 245
Query: 132 NIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTA 191
+ VL PS + + V LC + G P P W K D +LP
Sbjct: 246 ESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVK-GDPPPRLRWRKEDG--ELPTGR 302
Query: 192 TQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISP 235
+ + ++ I ++SA G Y CVA N++G + L V P
Sbjct: 303 YEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP 346
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 16/128 (12%)
Query: 107 INNTQLSDTGTYQC---------LVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI 157
I Q D G Y C L L +I G ++ +L P+ + +
Sbjct: 411 ITAVQRGDAGYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPA------NQTLVL 464
Query: 158 GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
GS V L C G P+P+ W+K L+ + GT+ I N+ + G Y CVA
Sbjct: 465 GSSVWLPCRVT-GNPQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVA 523
Query: 218 SNAIGTST 225
++ G +T
Sbjct: 524 KSSTGEAT 531
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 57.0 bits (136), Expect = 3e-08
Identities = 44/157 (28%), Positives = 71/157 (45%), Gaps = 10/157 (6%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQ---DIGSDVIL 163
I++ + SD GTY CL N + + V T + P AP Q + ++ + G L
Sbjct: 3172 ISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATL 3231
Query: 164 LCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQG-TVTIRNISALSSGLYQCVASNAIG 222
CS+ G P PT W KL + P Q +++G T+ I ++ SG Y C A++ G
Sbjct: 3232 RCSA-TGSPAPTIHWSKLRS-----PLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAG 3285
Query: 223 TSTCLLDLQVISPQPRNIGLIAGAIGTGAVIIIFCIA 259
+ + L V SP ++ G + + C+A
Sbjct: 3286 HAEATIILHVESPPYATTVPEHASVQAGETVQLQCLA 3322
Score = 56.2 bits (134), Expect = 6e-08
Identities = 59/189 (31%), Positives = 79/189 (41%), Gaps = 26/189 (13%)
Query: 63 PLSNANQPEQVILYQGGQ-----MFDGAP-------RFHGRVGFTGTMPATNVS-IFINN 109
PL P + I+ QGG G+P R GR +GT S + +
Sbjct: 1676 PLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSELHFPS 1735
Query: 110 TQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAP---HCQIQGSQDI--GSDVILL 164
Q SD G Y C NL N L V PS P + Q SQ + G+DV +
Sbjct: 1736 VQPSDAGVYICTCRNLHQ---SNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFI 1792
Query: 165 CSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASN--AIG 222
C+++ P T +W +L N KLP A G +TIRN+ +G Y C SN A+
Sbjct: 1793 CTAKSKSPAYTLVWTRLHNG-KLPTRAMD--FNGILTIRNVQLSDAGTYVCTGSNMFAMD 1849
Query: 223 TSTCLLDLQ 231
T L +Q
Sbjct: 1850 QGTATLHVQ 1858
Score = 51.2 bits (121), Expect = 2e-06
Identities = 63/259 (24%), Positives = 102/259 (39%), Gaps = 46/259 (17%)
Query: 158 GSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQ-GTVTIRNISALSSGLYQCV 216
G V L C + G+P T W K +L PP A ++ T+ I I+ +G Y CV
Sbjct: 1970 GRTVRLYCRAA-GVPSATITWRKEGGSL--PPQARSERTDIATLLIPAITTADAGFYLCV 2026
Query: 217 ASNAIGTSTCLLDLQVI-----SPQPRNIGLIAGAIGTGAVIIIFCIALILGAFFYWRSK 271
A++ GT+ + + V+ SP P I + ++ G + + C+ + G+
Sbjct: 2027 ATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCV--VAGS------- 2077
Query: 272 NKEEEEEEIPNEIREDDLPPKCSSAKAFHTEISSSDNNTLTSSNAYNSRYW-----SNNP 326
++ R LPP HT++ S S A + Y + P
Sbjct: 2078 ----AHAQVTWYRRGGSLPP--------HTQVHGSRLRLPQVSPADSGEYVCRVENGSGP 2125
Query: 327 KVHRNTESVSHFSDLGQSFSFHSGNANIPSIYANGTH-----------LVPGQHKTLVVT 375
K T SV H + G S++ G+ I + +H +VPGQ V
Sbjct: 2126 KEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTW 2185
Query: 376 ANRGSSPQVMSRSNGSVSR 394
RG S +++GS+ R
Sbjct: 2186 HKRGGSLPARHQTHGSLLR 2204
Score = 44.7 bits (104), Expect = 2e-04
Identities = 55/209 (26%), Positives = 81/209 (38%), Gaps = 47/209 (22%)
Query: 25 VSESPGSIQVARGQPAVLPCTFTTSAALINLNVIWMVTPLSNANQPEQVILYQGGQMFDG 84
+S P S V +GQ A C AA I+L W N + V + G +
Sbjct: 3024 ISIDPPSSTVQQGQDASFKCLIHDGAAPISLE--WKTR---NQELEDNVHISPNGSI--- 3075
Query: 85 APRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGR--NIGVTG-LTVL 141
+ GT P S+ GTY+C+ +N + N+ V G TV
Sbjct: 3076 -------ITIVGTRP-------------SNHGTYRCVASNAYGVAQSVVNLSVHGPPTVS 3115
Query: 142 VPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVT 201
V P P +G V L C S G PR + W ++ +T P + + G +
Sbjct: 3116 VLPEGPVW-----VKVGKAVTLECVS-AGEPRSSARWTRISST----PAKLEQRTYGLMD 3165
Query: 202 IRNISALSS------GLYQCVASNAIGTS 224
+ +SS G Y C+A NA+GT+
Sbjct: 3166 SHAVLQISSAKPSDAGTYVCLAQNALGTA 3194
Score = 40.8 bits (94), Expect = 0.002
Identities = 37/130 (28%), Positives = 55/130 (42%), Gaps = 17/130 (13%)
Query: 107 INNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDI----GSDVI 162
I + +L+D G Y+C N G T VL+ A QI Q++ GS +
Sbjct: 3542 IAHVELADAGQYRCTATNAA-------GTTQSHVLLLVQALP-QISMPQEVRVPAGSAAV 3593
Query: 163 LLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIG 222
C + G P P W KLD + LPP + + + + ++ +G Y C A+N G
Sbjct: 3594 FPCIAS-GYPTPDISWSKLDGS--LPPDSRLE--NNMLMLPSVRPQDAGTYVCTATNRQG 3648
Query: 223 TSTCLLDLQV 232
LQV
Sbjct: 3649 KVKAFAHLQV 3658
Score = 36.2 bits (82), Expect = 0.059
Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 10/82 (12%)
Query: 170 GIPRPTYLWEKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVASNAIGT--STCL 227
G P+P W K+ L+ P Q G V I ++ +G Y+C A+NA GT S L
Sbjct: 3514 GDPKPQVTWSKVGGHLR--PGIVQSG--GVVRIAHVELADAGQYRCTATNAAGTTQSHVL 3569
Query: 228 LDLQVISPQ---PRNIGLIAGA 246
L +Q + PQ P+ + + AG+
Sbjct: 3570 LLVQAL-PQISMPQEVRVPAGS 3590
Score = 35.4 bits (80), Expect = 0.10
Identities = 34/138 (24%), Positives = 54/138 (39%), Gaps = 25/138 (18%)
Query: 113 SDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPPS--------APHCQIQGSQDI---GSDV 161
+D+G Y C + P TV VPPS +P I G D
Sbjct: 2984 ADSGEYVCRAASGPGPEQE----ASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDA 3039
Query: 162 ILLCSSEEGIPRPTYLW----EKLDNTLKLPPTATQDQVQGTVTIRNISALSSGLYQCVA 217
C +G + W ++L++ + + P + +TI + G Y+CVA
Sbjct: 3040 SFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGS------IITIVGTRPSNHGTYRCVA 3093
Query: 218 SNAIGTSTCLLDLQVISP 235
SNA G + +++L V P
Sbjct: 3094 SNAYGVAQSVVNLSVHGP 3111
Score = 33.9 bits (76), Expect = 0.29
Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 8/86 (9%)
Query: 142 VPPSA---PHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPP--TATQDQV 196
+PP P IQ S+ G V C + G+P P W + P T T +
Sbjct: 404 MPPQVVTPPRESIQASR--GQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGG 460
Query: 197 QGTVTIRNISALSSGLYQCVASNAIG 222
+GT+ IR++ G Y C A NA G
Sbjct: 461 RGTLIIRDVKESDQGAYTCEAMNARG 486
Score = 31.2 bits (69), Expect = 1.9
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 3/79 (3%)
Query: 102 NVSIFINNTQLSDTGTYQCLVNNL--PDIGGRNIGVTGLTVLVPPSAPHCQIQGSQDIGS 159
N + I N QLSD GTY C +N+ D G + V L P Q + G
Sbjct: 1822 NGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQ 1881
Query: 160 DVILLCSSEEGIPRPTYLW 178
CS+ G P PT W
Sbjct: 1882 LAEFRCSA-TGSPTPTLEW 1899
Score = 28.9 bits (63), Expect = 9.4
Identities = 49/189 (25%), Positives = 69/189 (36%), Gaps = 28/189 (14%)
Query: 91 RVGFT--GTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVTGLTVLVPP---- 144
RVG + G A N + D+G Y+C V N G L V PP
Sbjct: 3334 RVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKV---GSAEAFAQLLVQGPPGSLP 3390
Query: 145 -------SAPHCQIQ---GSQDIGSDVILLCSSEEGIPRPTYL-WEKLDNTLKLPPTATQ 193
S P Q+ ++ IG+ V C+ R T L W K L P + Q
Sbjct: 3391 ATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPS--DRGTQLRWFKEGGQLP-PGHSVQ 3447
Query: 194 DQVQGTVTIRNISALSSGLYQCVASNAIG--TSTCLLDLQVISPQPRNIGLIAGAIGTGA 251
D G + I+N+ G Y C A G ++ L +Q + NI + G
Sbjct: 3448 D---GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGH 3504
Query: 252 VIIIFCIAL 260
+ C+AL
Sbjct: 3505 AVEFECLAL 3513
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,899,080
Number of Sequences: 37866
Number of extensions: 849935
Number of successful extensions: 5058
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 278
Number of HSP's that attempted gapping in prelim test: 3371
Number of HSP's gapped (non-prelim): 1425
length of query: 431
length of database: 18,247,518
effective HSP length: 105
effective length of query: 326
effective length of database: 14,271,588
effective search space: 4652537688
effective search space used: 4652537688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.