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Search of human proteins with 62243769
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62243769 signal transducing adaptor family member 2 isoform
2 [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62243769 signal transducing adaptor family member 2 isoform 2... 834 0.0
gi|62243734 signal transducing adaptor family member 2 isoform 1... 812 0.0
gi|6912272 signal transducing adaptor family member 1 [Homo sapi... 153 3e-37
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 47 2e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 47 2e-05
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 44 3e-04
gi|11386183 WAS protein family, member 2 [Homo sapiens] 43 4e-04
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 43 6e-04
gi|40353729 Ras and Rab interactor 3 [Homo sapiens] 43 6e-04
gi|51173735 ras responsive element binding protein 1 isoform 2 [... 42 8e-04
gi|51173737 ras responsive element binding protein 1 isoform 1 [... 42 8e-04
gi|41350201 epsin 1 isoform c [Homo sapiens] 42 8e-04
gi|194248095 epsin 1 isoform b [Homo sapiens] 42 8e-04
gi|194272148 epsin 1 isoform a [Homo sapiens] 42 8e-04
gi|153792074 proline rich 12 [Homo sapiens] 42 8e-04
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 42 0.001
gi|157168329 formin 1 [Homo sapiens] 41 0.002
gi|117938310 sine oculis binding protein homolog [Homo sapiens] 41 0.002
gi|33356148 formin-like 1 [Homo sapiens] 41 0.002
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 41 0.002
gi|110349719 titin isoform N2-A [Homo sapiens] 40 0.003
gi|52485606 formin-like 2 [Homo sapiens] 40 0.004
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 40 0.005
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 39 0.006
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s... 39 0.006
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ... 39 0.006
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ... 39 0.006
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s... 39 0.006
gi|145275195 Cdk5 and Abl enzyme substrate 2 [Homo sapiens] 39 0.006
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 39 0.006
>gi|62243769 signal transducing adaptor family member 2 isoform 2
[Homo sapiens]
Length = 403
Score = 834 bits (2154), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV 60
MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV
Sbjct: 1 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV 60
Query: 61 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR 120
EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR
Sbjct: 61 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR 120
Query: 121 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS 180
VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS
Sbjct: 121 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS 180
Query: 181 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA 240
GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA
Sbjct: 181 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA 240
Query: 241 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL 300
LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL
Sbjct: 241 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL 300
Query: 301 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPK 360
PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPK
Sbjct: 301 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPK 360
Query: 361 VFNGGLGRKLPVSSAQPLFPTAGLADMTAELQKKLEKRRALEH 403
VFNGGLGRKLPVSSAQPLFPTAGLADMTAELQKKLEKRRALEH
Sbjct: 361 VFNGGLGRKLPVSSAQPLFPTAGLADMTAELQKKLEKRRALEH 403
>gi|62243734 signal transducing adaptor family member 2 isoform 1
[Homo sapiens]
Length = 449
Score = 812 bits (2097), Expect = 0.0
Identities = 403/449 (89%), Positives = 403/449 (89%), Gaps = 46/449 (10%)
Query: 1 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV 60
MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV
Sbjct: 1 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV 60
Query: 61 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR 120
EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR
Sbjct: 61 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR 120
Query: 121 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS 180
VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS
Sbjct: 121 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS 180
Query: 181 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA 240
GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA
Sbjct: 181 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA 240
Query: 241 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL 300
LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL
Sbjct: 241 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL 300
Query: 301 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPK---- 356
PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPK
Sbjct: 301 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPVEK 360
Query: 357 ------------------------------------------PEPKVFNGGLGRKLPVSS 374
PEPKVFNGGLGRKLPVSS
Sbjct: 361 GFHHVAQAGLELLTSSDPPTSASQSAGITGVSHHTWPHLSSLPEPKVFNGGLGRKLPVSS 420
Query: 375 AQPLFPTAGLADMTAELQKKLEKRRALEH 403
AQPLFPTAGLADMTAELQKKLEKRRALEH
Sbjct: 421 AQPLFPTAGLADMTAELQKKLEKRRALEH 449
>gi|6912272 signal transducing adaptor family member 1 [Homo
sapiens]
Length = 295
Score = 153 bits (386), Expect = 3e-37
Identities = 94/277 (33%), Positives = 148/277 (53%), Gaps = 38/277 (13%)
Query: 4 ALRPPRVPKPKGVLPSH--------YYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNR 55
A +PP+ P P+ + Y+E FL K R+Y+ +W L+G T++FY +
Sbjct: 3 AKKPPK-PAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYTDKK 61
Query: 56 DFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILT 115
+V+KL++ LT++ S+ F+L+L +E++ K E E E W+GFILT
Sbjct: 62 SIIYVDKLDIVDLTCLTEQ---NSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGFILT 118
Query: 116 VVELRVPTDLTLLPGHLYMMSEVLAKEEARRALET-----------------------PS 152
V EL VP +++LLPG + + EVL +E+ RR +ET P+
Sbjct: 119 VTELSVPQNVSLLPGQVIKLHEVLEREKKRR-IETEQSTSVEKEKEPTEDYVDVLNPMPA 177
Query: 153 CFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKREGPK 212
CF VSR EA +L++ P GN++LRP D + S+T RQ + ++HYKV G
Sbjct: 178 CFYTVSRKEATEMLQKNPSLGNMILRPGSDSRN-YSITIRQEIDIPR-IKHYKVMSVGQN 235
Query: 213 YVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDED 249
Y I++E+P + +L +V++YFV T+ L PF+ D
Sbjct: 236 YTIELEKPVTLPNLFSVIDYFVKETRGNLRPFICSTD 272
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 47.4 bits (111), Expect = 2e-05
Identities = 35/107 (32%), Positives = 42/107 (39%), Gaps = 12/107 (11%)
Query: 273 APGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSSW 332
AP P P P GP PL P+SS + P P N + TP P S
Sbjct: 306 APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP----------GRSG 355
Query: 333 PVILKPKKLPKPPAKLPKPPVGPKPEPKVF--NGGLGRKLPVSSAQP 377
P+ P + P PP + P GP P P NG R LP + P
Sbjct: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 30/143 (20%)
Query: 271 PSAPGPGPAP---------CTGG----PKPLSPASSQDKLPPLPPLPNQEEN-----YVT 312
P P PGP P GG PLS +S PPLPP P++ +
Sbjct: 210 PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 313 PIGDGPAVDYE---NQDVASSSWPVILKPKKLPKPPAKLPKPP---VGPKPEPKVFNGG- 365
P+G+ P++ E ++ PV P+ A P PP GP P P +G
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND 329
Query: 366 -----LGRKLPVSSAQPLFPTAG 383
R L +SS+ P P+ G
Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPG 352
Score = 35.8 bits (81), Expect = 0.071
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 11/110 (10%)
Query: 271 PSAPGPGPAPCTG---GPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDV 327
PS PG P P G GP P ++++PP P + + + P ++
Sbjct: 144 PSGPGRFPVPSPGHRSGP----PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH 199
Query: 328 ASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQP 377
S PV P++ P+ P PP P GG R+ P+SS+ P
Sbjct: 200 NRGSPPVPGGPRQ----PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245
Score = 29.3 bits (64), Expect = 6.6
Identities = 24/92 (26%), Positives = 33/92 (35%), Gaps = 12/92 (13%)
Query: 270 APSAPGPGPAPCTGGPKP--LSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDV 327
+P GP P P + P P P LPP PP+ A+ Q
Sbjct: 350 SPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGST-------SRALPATPQLP 402
Query: 328 ASSSWPVILKPKKLPKPPAKLPKPPVGPKPEP 359
+ S + P+ P+PP +P G P P
Sbjct: 403 SRSG---VDSPRSGPRPPLPPDRPSAGAPPPP 431
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 47.4 bits (111), Expect = 2e-05
Identities = 35/107 (32%), Positives = 42/107 (39%), Gaps = 12/107 (11%)
Query: 273 APGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSSW 332
AP P P P GP PL P+SS + P P N + TP P S
Sbjct: 306 APPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP----------GRSG 355
Query: 333 PVILKPKKLPKPPAKLPKPPVGPKPEPKVF--NGGLGRKLPVSSAQP 377
P+ P + P PP + P GP P P NG R LP + P
Sbjct: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLP 402
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/143 (28%), Positives = 56/143 (39%), Gaps = 30/143 (20%)
Query: 271 PSAPGPGPAP---------CTGG----PKPLSPASSQDKLPPLPPLPNQEEN-----YVT 312
P P PGP P GG PLS +S PPLPP P++ +
Sbjct: 210 PRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPP 269
Query: 313 PIGDGPAVDYE---NQDVASSSWPVILKPKKLPKPPAKLPKPP---VGPKPEPKVFNGG- 365
P+G+ P++ E ++ PV P+ A P PP GP P P +G
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGND 329
Query: 366 -----LGRKLPVSSAQPLFPTAG 383
R L +SS+ P P+ G
Sbjct: 330 ETPRLPQRNLSLSSSTPPLPSPG 352
Score = 35.8 bits (81), Expect = 0.071
Identities = 30/110 (27%), Positives = 45/110 (40%), Gaps = 11/110 (10%)
Query: 271 PSAPGPGPAPCTG---GPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDV 327
PS PG P P G GP P ++++PP P + + + P ++
Sbjct: 144 PSGPGRFPVPSPGHRSGP----PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH 199
Query: 328 ASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQP 377
S PV P++ P+ P PP P GG R+ P+SS+ P
Sbjct: 200 NRGSPPVPGGPRQ----PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245
Score = 29.3 bits (64), Expect = 6.6
Identities = 24/92 (26%), Positives = 33/92 (35%), Gaps = 12/92 (13%)
Query: 270 APSAPGPGPAPCTGGPKP--LSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDV 327
+P GP P P + P P P LPP PP+ A+ Q
Sbjct: 350 SPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGST-------SRALPATPQLP 402
Query: 328 ASSSWPVILKPKKLPKPPAKLPKPPVGPKPEP 359
+ S + P+ P+PP +P G P P
Sbjct: 403 SRSG---VDSPRSGPRPPLPPDRPSAGAPPPP 431
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/119 (28%), Positives = 46/119 (38%), Gaps = 20/119 (16%)
Query: 271 PSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPI-------------GDG 317
P P P P GP P P Q + PP PP P+ TP+ G G
Sbjct: 482 PPPPSGQPPPPPSGPLP--PWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTG 539
Query: 318 PAVDYENQDVASSSWP----VILKPKKLPKPP-AKLPKPPVGPKPEPKVFNGGLGRKLP 371
++ Q A+++ P + P +P PP + P PP P P P G G +P
Sbjct: 540 SIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIP 598
Score = 33.1 bits (74), Expect = 0.46
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 277 GPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYV--TPIGDGPAVDYENQDVASSSWPV 334
GP P P P P +Q PP P + Y+ TP+G G ++ + + P+
Sbjct: 419 GPPPPWMQPPP--PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPP-PM 475
Query: 335 ILKPKKLPKPPAKLPKPPVGPKP 357
+ P P P + P PP GP P
Sbjct: 476 GMMPPPPPPPSGQPPPPPSGPLP 498
Score = 28.9 bits (63), Expect = 8.6
Identities = 27/117 (23%), Positives = 38/117 (32%), Gaps = 28/117 (23%)
Query: 272 SAPGPGPAPCTGGPKPLSPASSQDKLPPLPPL--------------PNQEENYVTPIGDG 317
S GP P P+P +PA++ PP P L P++ Y G G
Sbjct: 331 STSGPATTPLASAPRPAAPANN----PPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG 386
Query: 318 PAVD----------YENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNG 364
P + P+ P P P + P PP+ P P +G
Sbjct: 387 PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG 443
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 43.1 bits (100), Expect = 4e-04
Identities = 44/145 (30%), Positives = 57/145 (39%), Gaps = 21/145 (14%)
Query: 271 PSAPGPGPAPCTGGPKPLSP---ASSQDKLPPLPPL--PNQEENYVTPIGDGPAVDYENQ 325
P AP P P P G P P P S PP PP P+ + P PA DY
Sbjct: 319 PPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTL 378
Query: 326 DVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGR-KLPVSSAQPLFPTAGL 384
S P P P PP P PP GP P P F G G+ +P + P + L
Sbjct: 379 PPPPLSQPTGGAP---PPPP---PPPPPGPPPPP--FTGADGQPAIPPPLSDTTKPKSSL 430
Query: 385 -------ADMTAELQKKLEKRRALE 402
+D+ + +++ + RR E
Sbjct: 431 PAVSDARSDLLSAIRQGFQLRRVEE 455
Score = 35.8 bits (81), Expect = 0.071
Identities = 42/127 (33%), Positives = 50/127 (39%), Gaps = 29/127 (22%)
Query: 270 APSAPGPGPAPCTGGPKPLSPASSQDKLPPLP-----PLPNQEENYVTPIGDGPAVDYEN 324
A S P P + P SP+ S+D LPP P P+ NQ + + GP +
Sbjct: 243 ASSYPPPPQSDSASSP---SPSFSEDNLPPPPAEFSYPVDNQRGSGLA----GP----KR 291
Query: 325 QDVASSSWPVILKPKKLP--------KPPAKLPKPP--VG-PKPEPKVFNGGLGRKLPVS 373
V S S P P P PPA P PP +G P P P V G G P S
Sbjct: 292 SSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
Query: 374 SAQPLFP 380
P FP
Sbjct: 352 --PPSFP 356
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 42.7 bits (99), Expect = 6e-04
Identities = 39/113 (34%), Positives = 47/113 (41%), Gaps = 27/113 (23%)
Query: 269 VAPSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVA 328
++PS+P P P P P PPLPP P Q P GP V N
Sbjct: 1950 ISPSSPETPPPP----PPP----------PPLPPAPPQ------PSSMGP-VKIPN---- 1984
Query: 329 SSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPT 381
+ S P+ P P PP P PP P P P + +LPVS PLFP+
Sbjct: 1985 TVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPP--SAPPQVQLPVSLDLPLFPS 2035
Score = 32.7 bits (73), Expect = 0.60
Identities = 34/125 (27%), Positives = 48/125 (38%), Gaps = 28/125 (22%)
Query: 271 PSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASS 330
P P P P P PKP PA + P PP G PA+ ++S
Sbjct: 2345 PLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQ----------GTKPALPL----ASTS 2390
Query: 331 SWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGLADMTAE 390
S P P+ P+P P +P++ +GR P S++Q P++ L
Sbjct: 2391 SDP--------PQASTAQPQPQPQPPKQPQL----IGR--PPSASQTPVPSSPLQISMTS 2436
Query: 391 LQKKL 395
LQ L
Sbjct: 2437 LQNSL 2441
>gi|40353729 Ras and Rab interactor 3 [Homo sapiens]
Length = 985
Score = 42.7 bits (99), Expect = 6e-04
Identities = 42/138 (30%), Positives = 58/138 (42%), Gaps = 20/138 (14%)
Query: 270 APSAPGPGPA-----PCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYEN 324
AP P P P PC+ P+ PA + PLP P +VTP GP D+ N
Sbjct: 276 APRRPPPPPPVLPLQPCSPAQPPVLPALAPAPACPLPTSPPVPAPHVTPHAPGPP-DHPN 334
Query: 325 QDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGL 384
Q P ++ ++LP P A L GP E + G L A PL L
Sbjct: 335 Q-------PPMMTCERLPCPTAGL-----GPLREEAMKPGAASSPLQQVPAPPLPAKKNL 382
Query: 385 ADMTAELQKKLEKRRALE 402
TA ++++ +R +LE
Sbjct: 383 P--TAPPRRRVSERVSLE 398
>gi|51173735 ras responsive element binding protein 1 isoform 2 [Homo
sapiens]
Length = 1687
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/108 (34%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 260 DKENGENVWVAPSAPGPGPA-PCTGGPK-----PLSPASSQDKLPPLPPLPNQEENYVTP 313
++E G + +P P PGP+ P T GP P++PA + PP PL + V P
Sbjct: 960 EEEAGSSEQPSP-CPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAV-P 1017
Query: 314 IGDGPAVDYENQDVASS--SWPVILKPKKLPKPPAKLPKPPVGPKPEP 359
I V +S+ S +L+P + PKPP LPKPPV + P
Sbjct: 1018 IYSSALVSSPPLVGSSALLSGTALLRPLR-PKPPLLLPKPPVTEELPP 1064
>gi|51173737 ras responsive element binding protein 1 isoform 1 [Homo
sapiens]
Length = 1742
Score = 42.4 bits (98), Expect = 8e-04
Identities = 37/108 (34%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 260 DKENGENVWVAPSAPGPGPA-PCTGGPK-----PLSPASSQDKLPPLPPLPNQEENYVTP 313
++E G + +P P PGP+ P T GP P++PA + PP PL + V P
Sbjct: 960 EEEAGSSEQPSP-CPAPGPSLPVTLGPSGILESPMAPAPAATPEPPAQPLQGPVQLAV-P 1017
Query: 314 IGDGPAVDYENQDVASS--SWPVILKPKKLPKPPAKLPKPPVGPKPEP 359
I V +S+ S +L+P + PKPP LPKPPV + P
Sbjct: 1018 IYSSALVSSPPLVGSSALLSGTALLRPLR-PKPPLLLPKPPVTEELPP 1064
>gi|41350201 epsin 1 isoform c [Homo sapiens]
Length = 550
Score = 42.4 bits (98), Expect = 8e-04
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 22/87 (25%)
Query: 271 PSAPGPGPAPCTGGPKPLSPAS------SQDKLPPLPPLPNQEENYVTPIGDGPAVDYEN 324
P PG GPA P PA +Q +L P+PP+P Y++P+G GP
Sbjct: 477 PFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPG----- 531
Query: 325 QDVASSSWPVILKPKKLPKPPAKLPKP 351
L P P PPA P
Sbjct: 532 -----------LPPMMPPGPPAPNTNP 547
Score = 30.4 bits (67), Expect = 3.0
Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 19/148 (12%)
Query: 246 LDEDYEKVLGYVEADKENGENVWVAPSAPGP------GPAPCTGGPKPLSPASSQDKLPP 299
++E + G E+ + +V+ AP AP P GPAP +P S PP
Sbjct: 217 IEESKRETGGKEESSLMDLADVFTAP-APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 275
Query: 300 LPPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEP 359
+PP + P G GPA + D + P P P P GP P+P
Sbjct: 276 VPPAAD-------PWG-GPAPTPASGDPWRPAAPA--GPSVDPWGGTPAPAAGEGPTPDP 325
Query: 360 -KVFNGGLGRKLPVSSAQPLFPTAGLAD 386
+GG+ P S++ P P +D
Sbjct: 326 WGSSDGGVPVSGP-SASDPWTPAPAFSD 352
>gi|194248095 epsin 1 isoform b [Homo sapiens]
Length = 576
Score = 42.4 bits (98), Expect = 8e-04
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 22/87 (25%)
Query: 271 PSAPGPGPAPCTGGPKPLSPAS------SQDKLPPLPPLPNQEENYVTPIGDGPAVDYEN 324
P PG GPA P PA +Q +L P+PP+P Y++P+G GP
Sbjct: 503 PFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPG----- 557
Query: 325 QDVASSSWPVILKPKKLPKPPAKLPKP 351
L P P PPA P
Sbjct: 558 -----------LPPMMPPGPPAPNTNP 573
Score = 30.4 bits (67), Expect = 3.0
Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 19/148 (12%)
Query: 246 LDEDYEKVLGYVEADKENGENVWVAPSAPGP------GPAPCTGGPKPLSPASSQDKLPP 299
++E + G E+ + +V+ AP AP P GPAP +P S PP
Sbjct: 242 IEESKRETGGKEESSLMDLADVFTAP-APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 300
Query: 300 LPPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEP 359
+PP + P G GPA + D + P P P P GP P+P
Sbjct: 301 VPPAAD-------PWG-GPAPTPASGDPWRPAAPA--GPSVDPWGGTPAPAAGEGPTPDP 350
Query: 360 -KVFNGGLGRKLPVSSAQPLFPTAGLAD 386
+GG+ P S++ P P +D
Sbjct: 351 WGSSDGGVPVSGP-SASDPWTPAPAFSD 377
>gi|194272148 epsin 1 isoform a [Homo sapiens]
Length = 662
Score = 42.4 bits (98), Expect = 8e-04
Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 22/87 (25%)
Query: 271 PSAPGPGPAPCTGGPKPLSPAS------SQDKLPPLPPLPNQEENYVTPIGDGPAVDYEN 324
P PG GPA P PA +Q +L P+PP+P Y++P+G GP
Sbjct: 589 PFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPG----- 643
Query: 325 QDVASSSWPVILKPKKLPKPPAKLPKP 351
L P P PPA P
Sbjct: 644 -----------LPPMMPPGPPAPNTNP 659
Score = 30.4 bits (67), Expect = 3.0
Identities = 40/148 (27%), Positives = 58/148 (39%), Gaps = 19/148 (12%)
Query: 246 LDEDYEKVLGYVEADKENGENVWVAPSAPGP------GPAPCTGGPKPLSPASSQDKLPP 299
++E + G E+ + +V+ AP AP P GPAP +P S PP
Sbjct: 328 IEESKRETGGKEESSLMDLADVFTAP-APAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPP 386
Query: 300 LPPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEP 359
+PP + P G GPA + D + P P P P GP P+P
Sbjct: 387 VPPAAD-------PWG-GPAPTPASGDPWRPAAPA--GPSVDPWGGTPAPAAGEGPTPDP 436
Query: 360 -KVFNGGLGRKLPVSSAQPLFPTAGLAD 386
+GG+ P S++ P P +D
Sbjct: 437 WGSSDGGVPVSGP-SASDPWTPAPAFSD 463
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 42.4 bits (98), Expect = 8e-04
Identities = 32/97 (32%), Positives = 38/97 (39%), Gaps = 12/97 (12%)
Query: 269 VAPSAPGPGPAPCTGGPKPLS-----PASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYE 323
+AP+A PGP P G P S P ++K PP PP TP P
Sbjct: 1424 LAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP------PAPTPQPQPPPPPPP 1477
Query: 324 NQDVASSSWPVIL-KPKKLPKPPAKLPKPPVGPKPEP 359
Q S P++ P P PP P PP P P P
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPP 1514
Score = 29.6 bits (65), Expect = 5.1
Identities = 24/88 (27%), Positives = 26/88 (29%), Gaps = 41/88 (46%)
Query: 271 PSAPGPGPAPCTGGPKPL-SPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVAS 329
P P P P P P PL +P S PP PPLP
Sbjct: 1471 PPPPPPPPQPALPSPPPLVAPTPSS---PPPPPLP------------------------- 1502
Query: 330 SSWPVILKPKKLPKPPAKLPKPPVGPKP 357
P PP +P PP P P
Sbjct: 1503 ------------PPPPPAMPSPPPPPPP 1518
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/131 (26%), Positives = 49/131 (37%), Gaps = 22/131 (16%)
Query: 271 PSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPI-------------GDG 317
P P P P GP P P Q + PP PP P+ TP+ G G
Sbjct: 482 PPPPSGQPPPPPSGPLP--PWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTG 539
Query: 318 PAVDYENQDVASSSWP----VILKPKKLPKPPAKLPKPPVG---PKPEPKVFNGGLGRKL 370
++ Q A+++ P + P +P PP P P G P P P + G+
Sbjct: 540 SIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAP 599
Query: 371 PVSSAQPLFPT 381
P P+ P+
Sbjct: 600 PPPPPPPMDPS 610
Score = 33.1 bits (74), Expect = 0.46
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 5/83 (6%)
Query: 277 GPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYV--TPIGDGPAVDYENQDVASSSWPV 334
GP P P P P +Q PP P + Y+ TP+G G ++ + + P+
Sbjct: 419 GPPPPWMQPPP--PPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPP-PM 475
Query: 335 ILKPKKLPKPPAKLPKPPVGPKP 357
+ P P P + P PP GP P
Sbjct: 476 GMMPPPPPPPSGQPPPPPSGPLP 498
Score = 32.0 bits (71), Expect = 1.0
Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 5/59 (8%)
Query: 266 NVWVAPSAPGPGPAPCTGGPKPLSP-----ASSQDKLPPLPPLPNQEENYVTPIGDGPA 319
N + P PG P G P P P A PP PP P N+VT +G G A
Sbjct: 563 NPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVA 621
Score = 28.9 bits (63), Expect = 8.6
Identities = 27/117 (23%), Positives = 38/117 (32%), Gaps = 28/117 (23%)
Query: 272 SAPGPGPAPCTGGPKPLSPASSQDKLPPLPPL--------------PNQEENYVTPIGDG 317
S GP P P+P +PA++ PP P L P++ Y G G
Sbjct: 331 STSGPATTPLASAPRPAAPANN----PPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG 386
Query: 318 PAVD----------YENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNG 364
P + P+ P P P + P PP+ P P +G
Sbjct: 387 PGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHG 443
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 41.2 bits (95), Expect = 0.002
Identities = 36/120 (30%), Positives = 44/120 (36%), Gaps = 8/120 (6%)
Query: 248 EDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKL---PPLPPLP 304
+D L +E N + P A P P P G LSPA + PPLPP P
Sbjct: 625 KDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPP 684
Query: 305 NQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNG 364
P GP + +S P P PPA P P + P P P +F G
Sbjct: 685 PPPPPLPPPSSAGPPPPPPPPPLPNSPAP----PNPGGPPPAP-PPPGLAPPPPPGLFFG 739
>gi|117938310 sine oculis binding protein homolog [Homo sapiens]
Length = 873
Score = 41.2 bits (95), Expect = 0.002
Identities = 34/107 (31%), Positives = 41/107 (38%), Gaps = 23/107 (21%)
Query: 271 PSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASS 330
P PG GP P GGP+ L P SS P L P + P
Sbjct: 429 PMLPGIGPPP--GGPRNLGPTSSPMHRPMLSPHIHPPSTPTMP----------------G 470
Query: 331 SWPVILKPKKLPKPPAKLPKPPV-----GPKPEPKVFNGGLGRKLPV 372
+ P +L P P LP PPV GP P P++ N GL P+
Sbjct: 471 NPPGLLPPPPPGAPLPSLPFPPVSMMPNGPMPVPQMMNFGLPSLAPL 517
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 41.2 bits (95), Expect = 0.002
Identities = 34/117 (29%), Positives = 46/117 (39%), Gaps = 16/117 (13%)
Query: 269 VAPSAPGPGPAPC----TGGPKP-------LSPASSQDKLPPLPPLPNQEENYVTPIGDG 317
VA + P G AP TG P P +P ++ PPLP LP+ +E +
Sbjct: 506 VAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQA 565
Query: 318 PAVDYENQDVASSSWPVILKPKKLPKPP-----AKLPKPPVGPKPEPKVFNGGLGRK 369
P + + + P L P P PP +P PP P P P LGR+
Sbjct: 566 PPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRR 622
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 40.8 bits (94), Expect = 0.002
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 20/104 (19%)
Query: 264 GENVWVAPSAPGPGPAP------CTGGPK----PLSPASSQDKLPPLPPLPNQEENYVTP 313
G N+ + P+A G G P GGP P P S ++ P PP Q + P
Sbjct: 1182 GSNIPLHPNAQGTGGPPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAP 1241
Query: 314 IGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKP 357
G G Q P + PP LP P GP P
Sbjct: 1242 TGGGGGGPGLQQHY----------PSGMALPPEDLPNQPPGPMP 1275
Score = 30.4 bits (67), Expect = 3.0
Identities = 32/107 (29%), Positives = 44/107 (41%), Gaps = 13/107 (12%)
Query: 230 VNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLS 289
V F +H +L + +L Y + +NV A P P T P PLS
Sbjct: 240 VYVFTTHLANTAAEAVLQGRADSILAYHQ------QNVPRAKLDQAP-KVPPTPEPLPLS 292
Query: 290 PASS---QDKLPPLPPLPNQEENYVTPI--GDGPAVDYENQDVASSS 331
S+ Q + PPLPP P P +GP D +QD+A +S
Sbjct: 293 TPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPPED-SSQDLAPNS 338
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/130 (26%), Positives = 55/130 (42%), Gaps = 17/130 (13%)
Query: 244 FLLDEDYEKVLGYVEADKENGENVWVAPSAP--------GPGPAPCTGGPKPLSPASSQD 295
+L++E+ E Y+ ++E V P P P P P P +
Sbjct: 9921 YLVEEEEE----YIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPA 9976
Query: 296 KLPPLPPLPNQEENYVTPIGDGP----AVDYENQDVASSSWPVILKPKKLPKPPAKLPKP 351
K+P +P P ++ + P + P + + V PV + PKK+ PPAK+P+
Sbjct: 9977 KVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPV-PKKVEAPPAKVPEV 10035
Query: 352 PVGPKPEPKV 361
P P PE KV
Sbjct: 10036 PKKPVPEKKV 10045
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/150 (25%), Positives = 54/150 (36%), Gaps = 31/150 (20%)
Query: 212 KYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWVAP 271
K VI E+ F + + V+ V +K +V EK+ + E V P
Sbjct: 9239 KMVISEEKMFFASHTEEEVSVTVPEVQKEIVT------EEKIHVAISKRVEPPPKVPELP 9292
Query: 272 SAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSS 331
P P PK + P + K+P +P P EE P+
Sbjct: 9293 EKPAPEEVAPVPIPKKVEPPAP--KVPEVPKKPVPEEKKPVPV----------------- 9333
Query: 332 WPVILKPKKLPKPPAKLPKPPVGPKPEPKV 361
PKK P P K+P+ P P PE K+
Sbjct: 9334 ------PKKEPAAPPKVPEVPKKPVPEEKI 9357
Score = 35.4 bits (80), Expect = 0.092
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 5/87 (5%)
Query: 278 PAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVT---PIGDGPAVDYENQDVASSSWPV 334
PA P+P +P Q +PP P+P ++ V P V ++V
Sbjct: 10678 PAEVVEEPEPAAPP--QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVP 10735
Query: 335 ILKPKKLPKPPAKLPKPPVGPKPEPKV 361
++ PKK PPAK+P+ P PE KV
Sbjct: 10736 LVVPKKPEAPPAKVPEVPKEVVPEKKV 10762
Score = 33.5 bits (75), Expect = 0.35
Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 11/91 (12%)
Query: 271 PSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASS 330
P P P PK + P + K+P PP ++ VTP+ V ++V
Sbjct: 10571 PPKPESPPPEVPEAPKEVVP---EKKVPAAPP----KKPEVTPV----KVPEAPKEVVPE 10619
Query: 331 SWPVILKPKKLPKPPAKLPKPPVGPKPEPKV 361
+ PKK PP K+P+ P PE KV
Sbjct: 10620 KKVPVPPPKKPEVPPTKVPEVPKVAVPEKKV 10650
Score = 32.0 bits (71), Expect = 1.0
Identities = 25/83 (30%), Positives = 33/83 (39%), Gaps = 8/83 (9%)
Query: 280 PCTGGPKPLSPASS-QDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKP 338
P T P+ L P +K P+PP E P V ++V + P
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPE-------APPPKVPEAPKEVVPEKKVPVPPP 10543
Query: 339 KKLPKPPAKLPKPPVGPKPEPKV 361
KK PP K+P+ P PE KV
Sbjct: 10544 KKPEVPPTKVPEVPKAAVPEKKV 10566
Score = 31.6 bits (70), Expect = 1.3
Identities = 26/82 (31%), Positives = 36/82 (43%), Gaps = 9/82 (10%)
Query: 285 PKPLSPASSQDKLPPLPPLPNQEENYVTPIG---DGPAV---DYENQDVASSSWPVILKP 338
PK P + K+P +P P EE P+ + P + + V PV P
Sbjct: 9994 PKKEKPPPA--KVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPA-P 10050
Query: 339 KKLPKPPAKLPKPPVGPKPEPK 360
KK+ PPAK+P+ P PE K
Sbjct: 10051 KKVEAPPAKVPEVPKKLIPEEK 10072
Score = 31.2 bits (69), Expect = 1.7
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 3/69 (4%)
Query: 286 KPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSSWP--VILKPKKLPK 343
KP+ A ++ P P +P +E + P P + P VI KPK P+
Sbjct: 10822 KPVPVAEEEEPEVPPPAVP-EEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880
Query: 344 PPAKLPKPP 352
PP P PP
Sbjct: 10881 PPPPPPAPP 10889
Score = 31.2 bits (69), Expect = 1.7
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 9/63 (14%)
Query: 302 PLPNQEENYVTPIGDGPAVDYENQDVA-SSSWPVILKPK----KLPKPPAKLPKPPVGPK 356
P+ +EE V P PAV E + + PVI KP+ K P+P + KP + P+
Sbjct: 10825 PVAEEEEPEVPP----PAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880
Query: 357 PEP 359
P P
Sbjct: 10881 PPP 10883
Score = 30.8 bits (68), Expect = 2.3
Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Query: 285 PKPLSPASSQDKLPPLPPLPNQEENYVT-----PIGDGPAVDYENQDVASSSWPVILKPK 339
P P P K+P +P + E+ P P V E ++VA P + +
Sbjct: 10625 PPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEE 10684
Query: 340 KLPKPPAKLPKPPVGPKPEPK 360
P P ++ PP P PE K
Sbjct: 10685 PEPAAPPQVTVPPKKPVPEKK 10705
Score = 29.6 bits (65), Expect = 5.1
Identities = 13/24 (54%), Positives = 15/24 (62%)
Query: 338 PKKLPKPPAKLPKPPVGPKPEPKV 361
PKK PP K+P+ P P PE KV
Sbjct: 9598 PKKEKVPPPKVPEEPKKPVPEKKV 9621
Score = 28.9 bits (63), Expect = 8.6
Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 25/107 (23%)
Query: 267 VWVAPSAPGPGP-APCTGGPKPLSPASSQDKLPPL--PPLPNQEENYVTPIGDGPAVDYE 323
V V P P P AP KP +LPP+ P +P + V P P V +
Sbjct: 10693 VTVPPKKPVPEKKAPAVVAKKP--------ELPPVKVPEVPKE----VVPEKKVPLVVPK 10740
Query: 324 NQDVASSSWPVILK----------PKKLPKPPAKLPKPPVGPKPEPK 360
+ + P + K PKK PPAK+P+ P P E K
Sbjct: 10741 KPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEK 10787
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 28/114 (24%)
Query: 269 VAPSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVA 328
VA ++ GP + GP P P PPLPP + E + +GP
Sbjct: 509 VAGNSVGPTMGAASSGPLPPPP-------PPLPPSSDTPET----VQNGPVT-------- 549
Query: 329 SSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTA 382
P P PP P PP P P P G +P P P+A
Sbjct: 550 ---------PPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSA 594
Score = 29.6 bits (65), Expect = 5.1
Identities = 32/109 (29%), Positives = 35/109 (32%), Gaps = 42/109 (38%)
Query: 262 ENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVD 321
E +N V P P P P P P P P PP PPLP GPA +
Sbjct: 541 ETVQNGPVTPPMPPPPPPP----PPPPPPPPP----PPPPPLP------------GPAAE 580
Query: 322 YENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPK----VFNGGL 366
+P PP P P P P VFN GL
Sbjct: 581 ------------------TVPAPPLAPPLPSAPPLPGTSSPTVVFNSGL 611
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 39.7 bits (91), Expect = 0.005
Identities = 32/101 (31%), Positives = 40/101 (39%), Gaps = 10/101 (9%)
Query: 270 APSAPGPGPAPCTGGPKPLSPAS----SQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQ 325
APS P P P P T P PL P S LP PP P QEE +P PA +
Sbjct: 410 APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKR 469
Query: 326 DVASSSWPVILKPKKLPKPPAKL-PKPPVGPKPEPKVFNGG 365
P + ++ + A+ P+ P P P GG
Sbjct: 470 -----GRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGG 505
Score = 32.7 bits (73), Expect = 0.60
Identities = 30/110 (27%), Positives = 40/110 (36%), Gaps = 19/110 (17%)
Query: 271 PSAPGPGPAPCTGGPKPL-------SPASSQDKL------PPLPPLPNQEENYVTPIGDG 317
P AP P PAP T +PL +P+ + K+ PP P E P D
Sbjct: 628 PPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDS 687
Query: 318 P------AVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKV 361
P AV N PV+ P K P P GP+ + ++
Sbjct: 688 PAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQL 737
Score = 32.7 bits (73), Expect = 0.60
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 20/122 (16%)
Query: 270 APSAPGPGPAPCTGGPKPLSPAS-------SQDKLPPLPPLPNQEENYVTPIGDGPAVDY 322
AP AP P P P P P + S + P+ P + E V+P G PA+
Sbjct: 673 APEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAE--VSPHG-APALSN 729
Query: 323 ENQDVASSSWPV-----ILKPKKLPKPPAKLPKPPVGPKPEP---KVFNGGLGRKLPVSS 374
Q A P+ L P+ LP P +L +PP P+ P K G+G LP+S
Sbjct: 730 GPQTQAQLLQPLQALQTQLLPQALPPPQPQL-QPPPSPQQMPPLEKARIAGVG-SLPLSG 787
Query: 375 AQ 376
+
Sbjct: 788 VE 789
Score = 29.6 bits (65), Expect = 5.1
Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 47/121 (38%)
Query: 272 SAPGPGPAPCTGGPKPLSPASS--------------------------------QDKLPP 299
S P P P+ TGGP SP + D+ PP
Sbjct: 493 SPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPP 552
Query: 300 LPPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEP 359
PP + V+P+ P ++S PV +P +P PP + P PP P P P
Sbjct: 553 KPP-----KVEVSPVLRPP---------ITTSPPVPQEPAPVPSPP-RAPTPPSTPVPLP 597
Query: 360 K 360
+
Sbjct: 598 E 598
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 39.3 bits (90), Expect = 0.006
Identities = 29/102 (28%), Positives = 36/102 (35%), Gaps = 7/102 (6%)
Query: 271 PSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDG-------PAVDYE 323
P GP P P G P P S P PP P++ V P PA+
Sbjct: 294 PHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSS 353
Query: 324 NQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGG 365
P +L + PP P PP GP P P + + G
Sbjct: 354 APSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDG 395
Score = 32.7 bits (73), Expect = 0.60
Identities = 36/121 (29%), Positives = 43/121 (35%), Gaps = 25/121 (20%)
Query: 249 DYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPP--------L 300
D+ + G VEA K + AP P P P GGP P P PP
Sbjct: 257 DFIEKTGGVEAVKNE-----LRRQAPPP-PPPSRGGPPPPPPPPHNSGPPPPPARGRGAP 310
Query: 301 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKL--PKPPAKLPKPPVGPKPE 358
PP P++ P P VA P P ++ P PPA P GP P
Sbjct: 311 PPPPSR-----APTAAPPPPPPSRPSVAVPPPP----PNRMYPPPPPALPSSAPSGPPPP 361
Query: 359 P 359
P
Sbjct: 362 P 362
>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 39.3 bits (90), Expect = 0.006
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 22/113 (19%)
Query: 272 SAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSS 331
S P P PAP T P P+ P S PP P+ P G P Q S+S
Sbjct: 585 SVPAPAPAP-TPTPTPVQPTS-----PPPGPVAQ-------PTGPQP------QSAGSTS 625
Query: 332 WPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGL 384
PV P+ PP P P P P P + + +AQ L P GL
Sbjct: 626 GPV---PQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGL 675
Score = 35.8 bits (81), Expect = 0.071
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 14/103 (13%)
Query: 269 VAPSAPGPGPAPCTGGPKPLSPASSQDKLP-PLPPLPNQEENYVTPIGDGPAVDYENQDV 327
V P++P PGP GP+P S S+ +P P P P + P G P V Q
Sbjct: 600 VQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIP-VPAPPQIA 658
Query: 328 ASSS------------WPVILKPKKLPKPPAKLPKPPVGPKPE 358
S+S P P LP P LP P G P+
Sbjct: 659 TSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQ 701
>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 39.3 bits (90), Expect = 0.006
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 22/113 (19%)
Query: 272 SAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSS 331
S P P PAP T P P+ P S PP P+ P G P Q S+S
Sbjct: 585 SVPAPAPAP-TPTPTPVQPTS-----PPPGPVAQ-------PTGPQP------QSAGSTS 625
Query: 332 WPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGL 384
PV P+ PP P P P P P + + +AQ L P GL
Sbjct: 626 GPV---PQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGL 675
Score = 35.8 bits (81), Expect = 0.071
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 14/103 (13%)
Query: 269 VAPSAPGPGPAPCTGGPKPLSPASSQDKLP-PLPPLPNQEENYVTPIGDGPAVDYENQDV 327
V P++P PGP GP+P S S+ +P P P P + P G P V Q
Sbjct: 600 VQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIP-VPAPPQIA 658
Query: 328 ASSS------------WPVILKPKKLPKPPAKLPKPPVGPKPE 358
S+S P P LP P LP P G P+
Sbjct: 659 TSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQ 701
>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
sapiens]
Length = 816
Score = 39.3 bits (90), Expect = 0.006
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 22/113 (19%)
Query: 272 SAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSS 331
S P P PAP T P P+ P S PP P+ P G P Q S+S
Sbjct: 585 SVPAPAPAP-TPTPTPVQPTS-----PPPGPVAQ-------PTGPQP------QSAGSTS 625
Query: 332 WPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGL 384
PV P+ PP P P P P P + + +AQ L P GL
Sbjct: 626 GPV---PQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGL 675
Score = 35.8 bits (81), Expect = 0.071
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 14/103 (13%)
Query: 269 VAPSAPGPGPAPCTGGPKPLSPASSQDKLP-PLPPLPNQEENYVTPIGDGPAVDYENQDV 327
V P++P PGP GP+P S S+ +P P P P + P G P V Q
Sbjct: 600 VQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIP-VPAPPQIA 658
Query: 328 ASSS------------WPVILKPKKLPKPPAKLPKPPVGPKPE 358
S+S P P LP P LP P G P+
Sbjct: 659 TSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQ 701
>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
sapiens]
Length = 677
Score = 39.3 bits (90), Expect = 0.006
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 22/113 (19%)
Query: 272 SAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSS 331
S P P PAP T P P+ P S PP P+ P G P Q S+S
Sbjct: 446 SVPAPAPAP-TPTPTPVQPTS-----PPPGPVAQ-------PTGPQP------QSAGSTS 486
Query: 332 WPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGL 384
PV P+ PP P P P P P + + +AQ L P GL
Sbjct: 487 GPV---PQPACPPPGPAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGL 536
Score = 35.8 bits (81), Expect = 0.071
Identities = 32/103 (31%), Positives = 40/103 (38%), Gaps = 14/103 (13%)
Query: 269 VAPSAPGPGPAPCTGGPKPLSPASSQDKLP-PLPPLPNQEENYVTPIGDGPAVDYENQDV 327
V P++P PGP GP+P S S+ +P P P P + P G P V Q
Sbjct: 461 VQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIP-VPAPPQIA 519
Query: 328 ASSS------------WPVILKPKKLPKPPAKLPKPPVGPKPE 358
S+S P P LP P LP P G P+
Sbjct: 520 TSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQ 562
>gi|145275195 Cdk5 and Abl enzyme substrate 2 [Homo sapiens]
Length = 478
Score = 39.3 bits (90), Expect = 0.006
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 14/95 (14%)
Query: 270 APSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDG---PAVDYENQD 326
A + PGPAP GP P + +S + PP + GD A + +
Sbjct: 4 AAAGGAPGPAPGPAGPPPPAAPTSAARAPP---------QALRRRGDSRRRQAALFFLNN 54
Query: 327 VASSSWPVILKP--KKLPKPPAKLPKPPVGPKPEP 359
++ P L P +K P PPA+ +PP P PEP
Sbjct: 55 ISLDGRPPSLGPGGEKPPPPPAEAREPPAPPPPEP 89
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 39.3 bits (90), Expect = 0.006
Identities = 38/150 (25%), Positives = 56/150 (37%), Gaps = 19/150 (12%)
Query: 269 VAPSAPGPGPAPCTGGPKPLSPASSQ---DKLPPLPPLP------------NQEENYVTP 313
++P + +P T +P SP S LPP PP P +EE +P
Sbjct: 459 LSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESP 518
Query: 314 IGDGPAVDYENQDVASSSWPVILKPKKLPKP-PAKLPKPPVGPKPEPKVFNGGLGRKLPV 372
GP +++ AS+ P P P+ P PP +P + P
Sbjct: 519 SAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPP 578
Query: 373 SSAQPLFPT---AGLADMTAELQKKLEKRR 399
+ A P+ P+ AG D + EKRR
Sbjct: 579 APAPPVTPSKPMAGTTDREEATRLLAEKRR 608
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,951,045
Number of Sequences: 37866
Number of extensions: 1201930
Number of successful extensions: 8872
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 425
Number of HSP's that attempted gapping in prelim test: 6454
Number of HSP's gapped (non-prelim): 2019
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.