Search of human proteins with 61835232

Search of human proteins with 61835232

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61835232 growth differentiation factor 7 preproprotein [Homo
sapiens]
         (450 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61835232 growth differentiation factor 7 preproprotein [Homo ...   905   0.0  
gi|48475062 growth differentiation factor 6 precursor [Homo sapi...   313   2e-85
gi|4503969 growth differentiation factor 5 preproprotein [Homo s...   281   1e-75
gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sa...   150   2e-36
gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sa...   150   2e-36
gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sa...   150   2e-36
gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapi...   150   2e-36
gi|29571106 bone morphogenetic protein 8B preproprotein [Homo sa...   143   4e-34
gi|145611428 bone morphogenetic protein 8A [Homo sapiens]             138   1e-32
gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]      133   3e-31
gi|10835091 bone morphogenetic protein 5 preproprotein [Homo sap...   133   4e-31
gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapi...   129   4e-30
gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sap...   129   5e-30
gi|110349792 growth differentiation factor 1 [Homo sapiens]           120   3e-27
gi|7705308 growth differentiation factor 2 [Homo sapiens]             115   8e-26
gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sa...   113   3e-25
gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]     112   7e-25
gi|4826740 growth differentiation factor 10 precursor [Homo sapi...   107   2e-23
gi|222352098 nodal precursor [Homo sapiens]                           106   4e-23
gi|10190670 growth differentiation factor 3 precursor [Homo sapi...   105   8e-23
gi|13899338 activin beta E [Homo sapiens]                              96   7e-20
gi|4504699 inhibin beta A precursor [Homo sapiens]                     92   1e-18
gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]           89   6e-18
gi|4885259 myostatin [Homo sapiens]                                    87   4e-17
gi|5031613 growth differentiation factor 11 precursor [Homo sapi...    86   9e-17
gi|4885261 growth differentiation factor 9 precursor [Homo sapiens]    84   3e-16
gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]       79   6e-15
gi|153792495 growth differentiation factor 15 [Homo sapiens]           75   9e-14
gi|239757187 PREDICTED: similar to growth differentiation factor...    75   9e-14
gi|208022653 transforming growth factor, beta 2 isoform 1 [Homo ...    73   6e-13

>gi|61835232 growth differentiation factor 7 preproprotein [Homo
           sapiens]
          Length = 450

 Score =  905 bits (2338), Expect = 0.0
 Identities = 450/450 (100%), Positives = 450/450 (100%)

Query: 1   MDLSAAAALCLWLLSACRPRDGLEAAAVLRAAGAGPVRSPGGGGGGGGGGRTLAQAAGAA 60
           MDLSAAAALCLWLLSACRPRDGLEAAAVLRAAGAGPVRSPGGGGGGGGGGRTLAQAAGAA
Sbjct: 1   MDLSAAAALCLWLLSACRPRDGLEAAAVLRAAGAGPVRSPGGGGGGGGGGRTLAQAAGAA 60

Query: 61  AVPAAAVPRARAARRAAGSGFRNGSVVPHHFMMSLYRSLAGRAPAGAAAVSASGHGRADT 120
           AVPAAAVPRARAARRAAGSGFRNGSVVPHHFMMSLYRSLAGRAPAGAAAVSASGHGRADT
Sbjct: 61  AVPAAAVPRARAARRAAGSGFRNGSVVPHHFMMSLYRSLAGRAPAGAAAVSASGHGRADT 120

Query: 121 ITGFTDQATQDESAAETGQSFLFDVSSLNDADEVVGAELRVLRRGSPESGPGSWTSPPLL 180
           ITGFTDQATQDESAAETGQSFLFDVSSLNDADEVVGAELRVLRRGSPESGPGSWTSPPLL
Sbjct: 121 ITGFTDQATQDESAAETGQSFLFDVSSLNDADEVVGAELRVLRRGSPESGPGSWTSPPLL 180

Query: 181 LLSTCPGAARAPRLLYSRAAEPLVGQRWEAFDVADAMRRHRREPRPPRAFCLLLRAVAGP 240
           LLSTCPGAARAPRLLYSRAAEPLVGQRWEAFDVADAMRRHRREPRPPRAFCLLLRAVAGP
Sbjct: 181 LLSTCPGAARAPRLLYSRAAEPLVGQRWEAFDVADAMRRHRREPRPPRAFCLLLRAVAGP 240

Query: 241 VPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLFREIRAQARALGAALASEPL 300
           VPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLFREIRAQARALGAALASEPL
Sbjct: 241 VPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLFREIRAQARALGAALASEPL 300

Query: 301 PDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKE 360
           PDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKE
Sbjct: 301 PDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKE 360

Query: 361 LGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARL 420
           LGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARL
Sbjct: 361 LGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARL 420

Query: 421 SPISILYIDAANNVVYKQYEDMVVEACGCR 450
           SPISILYIDAANNVVYKQYEDMVVEACGCR
Sbjct: 421 SPISILYIDAANNVVYKQYEDMVVEACGCR 450


>gi|48475062 growth differentiation factor 6 precursor [Homo
           sapiens]
          Length = 455

 Score =  313 bits (802), Expect = 2e-85
 Identities = 194/405 (47%), Positives = 237/405 (58%), Gaps = 46/405 (11%)

Query: 68  PRARAARRAAGSGFRNGSVVPHHFMMSLYRSLAGRAPAGAAAVSASGHGRADTITGFTDQ 127
           PRA+  R     G R   VVPH +M+S+YR+ +     G  A        A+TIT F D+
Sbjct: 75  PRAQQPRAQEPPG-RGPRVVPHEYMLSIYRTYSIAEKLGINASFFQSSKSANTITSFVDR 133

Query: 128 ATQDESAAETG-QSFLFDVSSLNDADEVVGAELRVLRRGSPESGPGSWTSPPLLLLSTCP 186
              D S      Q +LFDVS L+D +E+VGAELR+ R+ +P +  G    P  + L  C 
Sbjct: 134 GLDDLSHTPLRRQKYLFDVSMLSDKEELVGAELRLFRQ-APSAPWGPPAGPLHVQLFPC- 191

Query: 187 GAARAPRLLYSRAAEPLVGQR--WEAFDVADAMRRHRREPRPPRAFCLLLRAVAGPV--- 241
               +P LL +R  +P       WE FDV   +R      +P +  CL LRA  G +   
Sbjct: 192 ---LSPLLLDARTLDPQGAPPAGWEVFDVWQGLRH-----QPWKQLCLELRAAWGELDAG 243

Query: 242 -----------PSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLFREIR----- 285
                      P P  LR LGFG         +ERA+LVV +R+QRK +LF E+R     
Sbjct: 244 EAEARARGPQQPPPPDLRSLGFG---RRVRPPQERALLVVFTRSQRK-NLFAEMREQLGS 299

Query: 286 AQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRG 345
           A+A   GA       P  G   A P     GRRRRRTA A            G+ HG++ 
Sbjct: 300 AEAAGPGAGAEGSWPPPSGAPDARPWLPSPGRRRRRTAFASRH---------GKRHGKKS 350

Query: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405
           R RCS+KPLHV+FKELGWDDWIIAPL+YEAYHCEG+CDFPLRSHLEPTNHAIIQTL+NSM
Sbjct: 351 RLRCSKKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSM 410

Query: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
            P + P SCCVP +L+PISILYIDA NNVVYKQYEDMVVE+CGCR
Sbjct: 411 DPGSTPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGCR 455


>gi|4503969 growth differentiation factor 5 preproprotein [Homo
           sapiens]
          Length = 501

 Score =  281 bits (718), Expect = 1e-75
 Identities = 165/405 (40%), Positives = 228/405 (56%), Gaps = 46/405 (11%)

Query: 58  GAAAVPAAAVPRARAARRAAGSG--------FRNGSVVPHHFMMSLYRSLAGRAPAGAAA 109
           G A   A +VP +   ++A   G        FR   + PH +M+SLYR+L+     G  +
Sbjct: 131 GKAPPKAGSVPSSFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGNS 190

Query: 110 VSASGHGRADTITGFTDQATQDESAAETGQSFLFDVSSLNDADEVVGAELRVLRRGSPE- 168
                 G A+TIT F D+   D       Q ++FD+S+L + D ++GAELR+LR+   + 
Sbjct: 191 SVKLEAGLANTITSFIDKGQDDRGPVVRKQRYVFDISAL-EKDGLLGAELRILRKKPSDT 249

Query: 169 ---SGPGSWTSPPLLLLSTCPGAARAPRLLYSRAAEPLVGQRWEAFDVADAMRRHRREPR 225
              + PG   +   L LS+CP   +   LL  R+   L G  WE FD+    R  +   +
Sbjct: 250 AKPAAPGGGRAAQ-LKLSSCPSGRQPASLLDVRSVPGLDGSGWEVFDIWKLFRNFKNSAQ 308

Query: 226 PPRAFCLLLRAVAGPVPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLFREIR 285
                 L L   A      + LR LGF           E+A+ +V  RT++++  F EI+
Sbjct: 309 ------LCLELEAWERGRAVDLRGLGF---DRAARQVHEKALFLVFGRTKKRDLFFNEIK 359

Query: 286 AQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRG 345
           A++               G    +    +  +RR+R A   TR         G+   +  
Sbjct: 360 ARS---------------GQDDKTVYEYLFSQRRKRRAPLATR--------QGKRPSKNL 396

Query: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405
           ++RCSRK LHV+FK++GWDDWIIAPL+YEA+HCEGLC+FPLRSHLEPTNHA+IQTL+NSM
Sbjct: 397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSM 456

Query: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
            P++ P +CCVP RLSPISIL+ID+ANNVVYKQYEDMVVE+CGCR
Sbjct: 457 DPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR 501


>gi|157276597 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score =  150 bits (379), Expect = 2e-36
 Identities = 111/349 (31%), Positives = 161/349 (46%), Gaps = 68/349 (19%)

Query: 117 RADTITGFTDQATQDESAAETGQS---FLFDVSSLNDADEVVGAELRVLRRGSPESGPGS 173
           RA+T+  F  +   +     +  S   FLF++SS+ + + +  AELR+ R    + GP  
Sbjct: 113 RANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFRE-QVDQGP-D 170

Query: 174 WT------------SPPLLLLSTCPGAARAPRLLYSRAAEPLVGQRWEAFDVADAMRRHR 221
           W              PP  ++   PG     RLL +R     V  RWE FDV+ A+ R  
Sbjct: 171 WERGFHRINIYEVMKPPAEVV---PGHL-ITRLLDTRLVHHNV-TRWETFDVSPAVLRWT 225

Query: 222 REPRPPRAFCLLLRAVAGPVPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLF 281
           RE +P     + +  +           R+    P G G+ A+ R +LV      R  +L 
Sbjct: 226 REKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALT 285

Query: 282 REIRAQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGH 341
           R                                  RR +R+    ++ A           
Sbjct: 286 RR---------------------------------RRAKRSPKHHSQRA----------- 301

Query: 342 GRRGRSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTL 401
            R+    C R  L+VDF ++GW+DWI+AP  Y+A++C G C FPL  HL  TNHAI+QTL
Sbjct: 302 -RKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL 360

Query: 402 LNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
           +NS+   + P +CCVP  LS IS+LY+D  + VV K Y++MVVE CGCR
Sbjct: 361 VNSV-NSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR 408


>gi|157276595 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score =  150 bits (379), Expect = 2e-36
 Identities = 111/349 (31%), Positives = 161/349 (46%), Gaps = 68/349 (19%)

Query: 117 RADTITGFTDQATQDESAAETGQS---FLFDVSSLNDADEVVGAELRVLRRGSPESGPGS 173
           RA+T+  F  +   +     +  S   FLF++SS+ + + +  AELR+ R    + GP  
Sbjct: 113 RANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFRE-QVDQGP-D 170

Query: 174 WT------------SPPLLLLSTCPGAARAPRLLYSRAAEPLVGQRWEAFDVADAMRRHR 221
           W              PP  ++   PG     RLL +R     V  RWE FDV+ A+ R  
Sbjct: 171 WERGFHRINIYEVMKPPAEVV---PGHL-ITRLLDTRLVHHNV-TRWETFDVSPAVLRWT 225

Query: 222 REPRPPRAFCLLLRAVAGPVPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLF 281
           RE +P     + +  +           R+    P G G+ A+ R +LV      R  +L 
Sbjct: 226 REKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALT 285

Query: 282 REIRAQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGH 341
           R                                  RR +R+    ++ A           
Sbjct: 286 RR---------------------------------RRAKRSPKHHSQRA----------- 301

Query: 342 GRRGRSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTL 401
            R+    C R  L+VDF ++GW+DWI+AP  Y+A++C G C FPL  HL  TNHAI+QTL
Sbjct: 302 -RKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL 360

Query: 402 LNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
           +NS+   + P +CCVP  LS IS+LY+D  + VV K Y++MVVE CGCR
Sbjct: 361 VNSV-NSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR 408


>gi|157276593 bone morphogenetic protein 4 preproprotein [Homo
           sapiens]
          Length = 408

 Score =  150 bits (379), Expect = 2e-36
 Identities = 111/349 (31%), Positives = 161/349 (46%), Gaps = 68/349 (19%)

Query: 117 RADTITGFTDQATQDESAAETGQS---FLFDVSSLNDADEVVGAELRVLRRGSPESGPGS 173
           RA+T+  F  +   +     +  S   FLF++SS+ + + +  AELR+ R    + GP  
Sbjct: 113 RANTVRSFHHEEHLENIPGTSENSAFRFLFNLSSIPENEVISSAELRLFRE-QVDQGP-D 170

Query: 174 WT------------SPPLLLLSTCPGAARAPRLLYSRAAEPLVGQRWEAFDVADAMRRHR 221
           W              PP  ++   PG     RLL +R     V  RWE FDV+ A+ R  
Sbjct: 171 WERGFHRINIYEVMKPPAEVV---PGHL-ITRLLDTRLVHHNV-TRWETFDVSPAVLRWT 225

Query: 222 REPRPPRAFCLLLRAVAGPVPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLF 281
           RE +P     + +  +           R+    P G G+ A+ R +LV      R  +L 
Sbjct: 226 REKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALT 285

Query: 282 REIRAQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGH 341
           R                                  RR +R+    ++ A           
Sbjct: 286 RR---------------------------------RRAKRSPKHHSQRA----------- 301

Query: 342 GRRGRSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTL 401
            R+    C R  L+VDF ++GW+DWI+AP  Y+A++C G C FPL  HL  TNHAI+QTL
Sbjct: 302 -RKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTL 360

Query: 402 LNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
           +NS+   + P +CCVP  LS IS+LY+D  + VV K Y++MVVE CGCR
Sbjct: 361 VNSV-NSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR 408


>gi|4557369 bone morphogenetic protein 2 preproprotein [Homo
           sapiens]
          Length = 396

 Score =  150 bits (379), Expect = 2e-36
 Identities = 121/382 (31%), Positives = 176/382 (46%), Gaps = 74/382 (19%)

Query: 85  SVVPHHFMMSLYRSLAGR----APAGAAAVSASGHGRADTITGFTDQATQDE---SAAET 137
           +VVP  +M+ LYR  +G+    AP      +AS   RA+T+  F  + + +E   ++ +T
Sbjct: 73  AVVPP-YMLDLYRRHSGQPGSPAPDHRLERAAS---RANTVRSFHHEESLEELPETSGKT 128

Query: 138 GQSFLFDVSSLNDADEVVGAELRVLRR------GSPESGPGSWTSPPLLLLSTCPGAARA 191
            + F F++SS+   + +  AEL+V R       G+  S         ++  +T       
Sbjct: 129 TRRFFFNLSSIPTEEFITSAELQVFREQMQDALGNNSSFHHRINIYEIIKPATANSKFPV 188

Query: 192 PRLLYSRAAEPLVGQ---RWEAFDVADAMRRHRREPRPPRAFCLLLRAVAGPVPSPLALR 248
            RLL +R    LV Q   RWE+FDV  A+ R   +      F + +  +           
Sbjct: 189 TRLLDTR----LVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEK-------- 236

Query: 249 RLGFGWPGGGGSAAEERAVLVVSSRTQRKESLFREIRAQARALGAALASEPLPDPGTGTA 308
                          +R V +  S  Q + S + +IR      G      PL        
Sbjct: 237 -----------QGVSKRHVRISRSLHQDEHS-WSQIRPLLVTFGHDGKGHPLH------- 277

Query: 309 SPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKELGWDDWII 368
                   +R +R A    R              +R +S C R PL+VDF ++GW+DWI+
Sbjct: 278 --------KREKRQAKHKQR--------------KRLKSSCKRHPLYVDFSDVGWNDWIV 315

Query: 369 APLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYI 428
           AP  Y A++C G C FPL  HL  TNHAI+QTL+NS+     P +CCVP  LS IS+LY+
Sbjct: 316 APPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSV-NSKIPKACCVPTELSAISMLYL 374

Query: 429 DAANNVVYKQYEDMVVEACGCR 450
           D    VV K Y+DMVVE CGCR
Sbjct: 375 DENEKVVLKNYQDMVVEGCGCR 396


>gi|29571106 bone morphogenetic protein 8B preproprotein [Homo
           sapiens]
          Length = 402

 Score =  143 bits (360), Expect = 4e-34
 Identities = 68/141 (48%), Positives = 91/141 (64%)

Query: 309 SPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKELGWDDWII 368
           +PRAV   RRR+         A    G     HG  GR  C R  L+V F++LGW DW+I
Sbjct: 261 TPRAVRPLRRRQPKKSNELPQANRLPGIFDDVHGSHGRQVCRRHELYVSFQDLGWLDWVI 320

Query: 369 APLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYI 428
           AP  Y AY+CEG C FPL S +  TNHAI+Q+L++ M PDA P +CC P +LS  S+LY 
Sbjct: 321 APQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPDAVPKACCAPTKLSATSVLYY 380

Query: 429 DAANNVVYKQYEDMVVEACGC 449
           D++NNV+ +++ +MVV+ACGC
Sbjct: 381 DSSNNVILRKHRNMVVKACGC 401


>gi|145611428 bone morphogenetic protein 8A [Homo sapiens]
          Length = 402

 Score =  138 bits (347), Expect = 1e-32
 Identities = 66/141 (46%), Positives = 90/141 (63%)

Query: 309 SPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKELGWDDWII 368
           +PRAV   RRR+         A    G      G  GR  C R  L+V F++LGW DW+I
Sbjct: 261 TPRAVRPLRRRQPKKSNELPQANRLPGIFDDVRGSHGRQVCRRHELYVSFQDLGWLDWVI 320

Query: 369 APLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYI 428
           AP  Y AY+CEG C FPL S +  TNHAI+Q+L++ M P+A P +CC P +LS  S+LY 
Sbjct: 321 APQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMKPNAVPKACCAPTKLSATSVLYY 380

Query: 429 DAANNVVYKQYEDMVVEACGC 449
           D++NNV+ +++ +MVV+ACGC
Sbjct: 381 DSSNNVILRKHRNMVVKACGC 401


>gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]
          Length = 431

 Score =  133 bits (335), Expect = 3e-31
 Identities = 55/104 (52%), Positives = 75/104 (72%)

Query: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405
           R  C +  L+V F++LGW DWIIAP  Y AY+CEG C FPL S++  TNHAI+QTL++ +
Sbjct: 327 RQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFI 386

Query: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
            P+  P  CC P +L+ IS+LY D ++NV+ K+Y +MVV ACGC
Sbjct: 387 NPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGC 430


>gi|10835091 bone morphogenetic protein 5 preproprotein [Homo
           sapiens]
          Length = 454

 Score =  133 bits (334), Expect = 4e-31
 Identities = 53/104 (50%), Positives = 75/104 (72%)

Query: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405
           +  C +  L+V F++LGW DWIIAP  Y A++C+G C FPL +H+  TNHAI+QTL++ M
Sbjct: 350 KQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLM 409

Query: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
            PD  P  CC P +L+ IS+LY D ++NV+ K+Y +MVV +CGC
Sbjct: 410 FPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGC 453


>gi|4502425 bone morphogenetic protein 6 preproprotein [Homo
           sapiens]
          Length = 513

 Score =  129 bits (325), Expect = 4e-30
 Identities = 53/104 (50%), Positives = 74/104 (71%)

Query: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405
           ++ C +  L+V F++LGW DWIIAP  Y A +C+G C FPL +H+  TNHAI+QTL++ M
Sbjct: 409 KTACRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLM 468

Query: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
            P+  P  CC P +L+ IS+LY D  +NV+ K+Y +MVV ACGC
Sbjct: 469 NPEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 512


>gi|7656928 bone morphogenetic protein 10 preproprotein [Homo
           sapiens]
          Length = 424

 Score =  129 bits (324), Expect = 5e-30
 Identities = 59/103 (57%), Positives = 71/103 (68%), Gaps = 2/103 (1%)

Query: 349 CSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPD 408
           C R PL++DFKE+GWD WIIAP  YEAY C G+C++PL  HL PT HAIIQ L++     
Sbjct: 323 CKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQ 382

Query: 409 AAPASCCVPARLSPISILYIDAANNVVYK-QYEDMVVEACGCR 450
            A  +CCVP +L PISILY+D    V YK +YE M V  CGCR
Sbjct: 383 KASKACCVPTKLEPISILYLD-KGVVTYKFKYEGMAVSECGCR 424


>gi|110349792 growth differentiation factor 1 [Homo sapiens]
          Length = 372

 Score =  120 bits (300), Expect = 3e-27
 Identities = 101/299 (33%), Positives = 133/299 (44%), Gaps = 50/299 (16%)

Query: 163 RRGSPESGPG---SWTSPPLLLLSTCPGAARAPR----LLYSRAAEPLVGQRWEAFDVAD 215
           R   P S  G    WT   +  LS    A R  R    L ++ AA       WE   VA 
Sbjct: 113 RASEPASAAGHCPEWTV--VFDLSAVEPAERPSRARLELRFAAAAAAAPEGGWE-LSVAQ 169

Query: 216 AMRRHRREPRPPRAFCLLLRAVAGPVPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQ 275
           A +    +P P     +LLR +   +  P+    LG  W          R  L       
Sbjct: 170 AGQGAGADPGP-----VLLRQLVPALGPPVRAELLGAAWARNASWPRSLRLALA------ 218

Query: 276 RKESLFREIRAQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGG 335
                   +R +A A  A LA   L      T  PR      R RR A          GG
Sbjct: 219 --------LRPRAPAACARLAEASLL---LVTLDPRLCHPLARPRRDA------EPVLGG 261

Query: 336 GAGRGHGRRGRSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLR---SHLEP 392
           G G          C  + L+V F+E+GW  W+IAP  + A +C+G C  P+    S   P
Sbjct: 262 GPG--------GACRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPVALSGSGGPP 313

Query: 393 T-NHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
             NHA+++ L+++ AP AA   CCVPARLSPIS+L+ D ++NVV +QYEDMVV+ CGCR
Sbjct: 314 ALNHAVLRALMHAAAPGAADLPCCVPARLSPISVLFFDNSDNVVLRQYEDMVVDECGCR 372


>gi|7705308 growth differentiation factor 2 [Homo sapiens]
          Length = 429

 Score =  115 bits (288), Expect = 8e-26
 Identities = 58/120 (48%), Positives = 72/120 (60%), Gaps = 6/120 (5%)

Query: 337 AGRGHGRRGRS-----RCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLE 391
           AG    RR RS      C +  L V+F+++GWD WIIAP +YEAY C+G C FPL   + 
Sbjct: 310 AGSTLARRKRSAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVT 369

Query: 392 PTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYK-QYEDMVVEACGCR 450
           PT HAI+QTL++   P     +CCVP +LSPIS+LY D       K  YE M V  CGCR
Sbjct: 370 PTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGCR 429


>gi|126507087 bone morphogenetic protein 3 preproprotein [Homo
           sapiens]
          Length = 472

 Score =  113 bits (283), Expect = 3e-25
 Identities = 47/103 (45%), Positives = 70/103 (67%), Gaps = 1/103 (0%)

Query: 349 CSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM-AP 407
           C+R+ L VDF ++GW +WII+P  ++AY+C G C FP+   L+P+NHA IQ+++ ++   
Sbjct: 370 CARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVV 429

Query: 408 DAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
              P  CCVP ++S +SIL+ D   NVV K Y +M VE+C CR
Sbjct: 430 PGIPEPCCVPEKMSSLSILFFDENKNVVLKVYPNMTVESCACR 472


>gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]
          Length = 392

 Score =  112 bits (280), Expect = 7e-25
 Identities = 54/134 (40%), Positives = 75/134 (55%), Gaps = 3/134 (2%)

Query: 320 RRTALAGTRTAQGSGG---GAGRGHGRRGRSRCSRKPLHVDFKELGWDDWIIAPLDYEAY 376
           R + L  TR A G       +   H     ++CS  P  + F++LGWD WIIAP  Y   
Sbjct: 259 RESLLRRTRQADGISAEVTASSSKHSGPENNQCSLHPFQISFRQLGWDHWIIAPPFYTPN 318

Query: 377 HCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVY 436
           +C+G C   LR  L   NHAIIQ L+N +   + P   CVP +  PIS+L I+A  +++Y
Sbjct: 319 YCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILY 378

Query: 437 KQYEDMVVEACGCR 450
           K+YE M+ E+C CR
Sbjct: 379 KEYEGMIAESCTCR 392


>gi|4826740 growth differentiation factor 10 precursor [Homo
           sapiens]
          Length = 478

 Score =  107 bits (268), Expect = 2e-23
 Identities = 43/103 (41%), Positives = 70/103 (67%), Gaps = 1/103 (0%)

Query: 349 CSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMA-P 407
           CSR+ L VDF ++GW++WII+P  ++AY+C G C+FP+   + P+NHA IQ+++ ++   
Sbjct: 376 CSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGII 435

Query: 408 DAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
              P  CCVP +++ + +L++D   NVV K Y +M V+ C CR
Sbjct: 436 PGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR 478


>gi|222352098 nodal precursor [Homo sapiens]
          Length = 347

 Score =  106 bits (265), Expect = 4e-23
 Identities = 51/116 (43%), Positives = 65/116 (56%), Gaps = 2/116 (1%)

Query: 335 GGAGRGHGRRGRSRCSRK-PLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPT 393
           G   R H    RS+  RK    VDF  +GW  WII P  Y AY CEG C  P+     PT
Sbjct: 232 GKRHRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPT 291

Query: 394 NHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
           NHA IQ+LL    P   P++CC P +  P+S+LY+D    V+   ++DM+VE CGC
Sbjct: 292 NHAYIQSLLKRYQPHRVPSTCCAPVKTKPLSMLYVD-NGRVLLDHHKDMIVEECGC 346



 Score = 28.9 bits (63), Expect = 9.9
 Identities = 36/114 (31%), Positives = 48/114 (42%), Gaps = 26/114 (22%)

Query: 60  AAVPAAAVPRARAARRAAGSGFRNGSVVPHHFMMSLYRSLAGRAPAGAAAVSASGHGRAD 119
           A + A A   A A  R  G   +  S  P  +M+SLYR    RA               D
Sbjct: 15  ALLQAGAATVATALLRTRG---QPSSPSPLAYMLSLYRDPLPRA---------------D 56

Query: 120 TITGFTDQATQDESAAETGQS--FLFDVSSLNDADEVVGAELRVLRRGSPESGP 171
            I     ++ Q E  A  GQ+  F FD S L+  +++  AELR L+  SP   P
Sbjct: 57  II-----RSLQAEDVAVDGQNWTFAFDFSFLSQQEDLAWAELR-LQLSSPVDLP 104


>gi|10190670 growth differentiation factor 3 precursor [Homo
           sapiens]
          Length = 364

 Score =  105 bits (262), Expect = 8e-23
 Identities = 46/104 (44%), Positives = 70/104 (67%), Gaps = 1/104 (0%)

Query: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405
           ++ C R  L ++F++LGW  WIIAP  + A +C G C F L   L  +N+A +Q L++++
Sbjct: 261 KNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAV 320

Query: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
            P+  P + C+P +LSPIS+LY D  +NV+ + YEDMVV+ CGC
Sbjct: 321 DPE-IPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGC 363


>gi|13899338 activin beta E [Homo sapiens]
          Length = 350

 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 57/160 (35%), Positives = 76/160 (47%), Gaps = 5/160 (3%)

Query: 295 LASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHG---RRGRSRCSR 351
           L   PL    T T  PR ++     ++  L     A   G G  R            C R
Sbjct: 190 LDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCR 249

Query: 352 KPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSH--LEPTNHAIIQTLLNSMAPDA 409
           +  +VDF+ELGW DWI+ P  Y+  +C G C   L     +  + H+ + +LL +  P  
Sbjct: 250 RDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWP 309

Query: 410 APASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
           A  SCCVP    P+S+LY+D   NVV     DMVVEACGC
Sbjct: 310 ASTSCCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349


>gi|4504699 inhibin beta A precursor [Homo sapiens]
          Length = 426

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 45/109 (41%), Positives = 65/109 (59%), Gaps = 12/109 (11%)

Query: 349 CSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQ---TLLNSM 405
           C +K   V FK++GW+DWIIAP  Y A +CEG C     SH+  T+ + +    T++N  
Sbjct: 321 CCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECP----SHIAGTSGSSLSFHSTVINHY 376

Query: 406 -----APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
                +P A   SCCVP +L P+S+LY D   N++ K  ++M+VE CGC
Sbjct: 377 RMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGC 425


>gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]
          Length = 352

 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 55/147 (37%), Positives = 70/147 (47%), Gaps = 6/147 (4%)

Query: 308 ASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSR-CSRKPLHVDFKELGWDDW 366
           A    ++GG   R    A  R   G      RG   +G SR C R+   VDF+E+GW DW
Sbjct: 206 AQSSVILGGAAHRPFVAARVRVG-GKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDW 264

Query: 367 IIAPLDYEAYHCEGLCDFPLRSH--LEPTNHAIIQTLL--NSMAPDAAPASCCVPARLSP 422
           II P  Y    C G C   +     +  + H  +  LL  N+ A      SCCVP    P
Sbjct: 265 IIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRP 324

Query: 423 ISILYIDAANNVVYKQYEDMVVEACGC 449
           +S+LY D  +N+V     DMVVEACGC
Sbjct: 325 LSLLYYDRDSNIVKTDIPDMVVEACGC 351


>gi|4885259 myostatin [Homo sapiens]
          Length = 375

 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 41/103 (39%), Positives = 58/103 (56%), Gaps = 7/103 (6%)

Query: 347 SRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMA 406
           SRC R PL VDF+  GWD WIIAP  Y+A +C G C+F        T+      L++   
Sbjct: 279 SRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGECEFVFLQKYPHTH------LVHQAN 331

Query: 407 PDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
           P  +   CC P ++SPI++LY +    ++Y +   MVV+ CGC
Sbjct: 332 PRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGC 374


>gi|5031613 growth differentiation factor 11 precursor [Homo
           sapiens]
          Length = 407

 Score = 85.5 bits (210), Expect = 9e-17
 Identities = 40/103 (38%), Positives = 57/103 (55%), Gaps = 7/103 (6%)

Query: 347 SRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMA 406
           SRC R PL VDF+  GWD WIIAP  Y+A +C G C++        T+      L+    
Sbjct: 311 SRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGQCEYMFMQKYPHTH------LVQQAN 363

Query: 407 PDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
           P  +   CC P ++SPI++LY +    ++Y +   MVV+ CGC
Sbjct: 364 PRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGC 406


>gi|4885261 growth differentiation factor 9 precursor [Homo sapiens]
          Length = 454

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 34/105 (32%), Positives = 56/105 (53%)

Query: 346 RSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSM 405
           ++ C      + F +L WD+WI+AP  Y   +C+G C   +        H ++Q ++   
Sbjct: 350 QNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAVGHRYGSPVHTMVQNIIYEK 409

Query: 406 APDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR 450
              + P   CVPA+ SP+S+L I+   ++ YK+YEDM+   C CR
Sbjct: 410 LDSSVPRPSCVPAKYSPLSVLTIEPDGSIAYKEYEDMIATKCTCR 454


>gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]
          Length = 407

 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 43/116 (37%), Positives = 63/116 (54%), Gaps = 6/116 (5%)

Query: 339 RGHGRRGRSR-CSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLR---SHLEPTN 394
           RG    GR+  C R+   +DF+ +GW+DWIIAP  Y   +CEG C   L          +
Sbjct: 292 RGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFH 351

Query: 395 HAII-QTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449
            A++ Q  +  + P     SCC+P +LS +S+LY D   N+V +   +M+VE CGC
Sbjct: 352 TAVVNQYRMRGLNPGTV-NSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406


>gi|153792495 growth differentiation factor 15 [Homo sapiens]
          Length = 308

 Score = 75.5 bits (184), Expect = 9e-14
 Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 23/197 (11%)

Query: 265 RAVLVVSSRTQRKESLFREIRAQ---ARALGAALASEPLPDPG--------TGTASPRAV 313
           RA+  +S    R   + R +R Q   AR    AL     P P         + +A P+  
Sbjct: 122 RALFRLSPTASRSWDVTRPLRRQLSLARPQAPALHLRLSPPPSQSDQLLAESSSARPQLE 181

Query: 314 IGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSR-KPLHVDFKELGWDDWIIAPLD 372
           +     R  A  G R A+   G     H   G  RC R   +    ++LGW DW+++P +
Sbjct: 182 L---HLRPQAARGRRRARARNGD----HCPLGPGRCCRLHTVRASLEDLGWADWVLSPRE 234

Query: 373 YEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAAN 432
            +   C G C    R+      HA I+T L+ + PD  PA CCVPA  +P+ +L      
Sbjct: 235 VQVTMCIGACPSQFRA---ANMHAQIKTSLHRLKPDTVPAPCCVPASYNPM-VLIQKTDT 290

Query: 433 NVVYKQYEDMVVEACGC 449
            V  + Y+D++ + C C
Sbjct: 291 GVSLQTYDDLLAKDCHC 307


>gi|239757187 PREDICTED: similar to growth differentiation factor 15
           [Homo sapiens]
          Length = 270

 Score = 75.5 bits (184), Expect = 9e-14
 Identities = 57/197 (28%), Positives = 86/197 (43%), Gaps = 23/197 (11%)

Query: 265 RAVLVVSSRTQRKESLFREIRAQ---ARALGAALASEPLPDPG--------TGTASPRAV 313
           RA+  +S    R   + R +R Q   AR    AL     P P         + +A P+  
Sbjct: 84  RALFRLSPTASRSWDVTRPLRRQLSLARPQAPALHLRLSPPPSQSDQLLAESSSARPQLE 143

Query: 314 IGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSR-KPLHVDFKELGWDDWIIAPLD 372
           +     R  A  G R A+   G     H   G  RC R   +    ++LGW DW+++P +
Sbjct: 144 L---HLRPQAARGRRRARARNGD----HCPLGPGRCCRLHTVRASLEDLGWADWVLSPRE 196

Query: 373 YEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAAN 432
            +   C G C    R+      HA I+T L+ + PD  PA CCVPA  +P+ +L      
Sbjct: 197 VQVTMCIGACPSQFRA---ANMHAQIKTSLHRLKPDTVPAPCCVPASYNPM-VLIQKTDT 252

Query: 433 NVVYKQYEDMVVEACGC 449
            V  + Y+D++ + C C
Sbjct: 253 GVSLQTYDDLLAKDCHC 269


>gi|208022653 transforming growth factor, beta 2 isoform 1 [Homo
           sapiens]
          Length = 442

 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 80/315 (25%), Positives = 125/315 (39%), Gaps = 41/315 (13%)

Query: 143 FDVSSLN-DADEVVGAELRVLRRGSPESGPGSWTSPPLLLLSTCPGAARAPRLLYSRAAE 201
           FDVS++  +A  +V AE RV R  +P++           +L +    +   R + S+  +
Sbjct: 160 FDVSAMEKNASNLVKAEFRVFRLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVK 219

Query: 202 PLVGQRWEAFDVADAMRRHRREPRPPRAFCLLLRAVAGP-VPS-----PLALRRLGFGWP 255
                 W +FDV DA+            F + L       VPS     P     L   + 
Sbjct: 220 TRAEGEWLSFDVTDAVHEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFA 279

Query: 256 GGGGSAAEERAVLVVSSRTQRKESLFREIRAQARALGAALASEPLPDPGTGTASPRAVIG 315
           G  G++            T++K S           L   L S  L    T          
Sbjct: 280 GIDGTSTYTSGDQKTIKSTRKKNS-----GKTPHLLLMLLPSYRLESQQTN--------- 325

Query: 316 GRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFK-ELGWDDWIIAPLDYE 374
             RR++ AL                  R  +  C  +PL++DFK +LGW  WI  P  Y 
Sbjct: 326 --RRKKRALDAAYCF------------RNVQDNCCLRPLYIDFKRDLGWK-WIHEPKGYN 370

Query: 375 AYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNV 434
           A  C G C +   S    T H+ + +L N++ P+A+ + CCV   L P++ILY       
Sbjct: 371 ANFCAGACPYLWSSD---TQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPK 427

Query: 435 VYKQYEDMVVEACGC 449
           + +Q  +M+V++C C
Sbjct: 428 I-EQLSNMIVKSCKC 441


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,783,883
Number of Sequences: 37866
Number of extensions: 1102043
Number of successful extensions: 15660
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 289
Number of HSP's successfully gapped in prelim test: 354
Number of HSP's that attempted gapping in prelim test: 10056
Number of HSP's gapped (non-prelim): 3805
length of query: 450
length of database: 18,247,518
effective HSP length: 106
effective length of query: 344
effective length of database: 14,233,722
effective search space: 4896400368
effective search space used: 4896400368
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.