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Search of human proteins with 61743973
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61743973 SORCS receptor 1 isoform a [Homo sapiens]
(1168 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61743973 SORCS receptor 1 isoform a [Homo sapiens] 2374 0.0
gi|61743975 SORCS receptor 1 isoform b [Homo sapiens] 2289 0.0
gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo sapiens] 1521 0.0
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens] 970 0.0
gi|4507157 sortilin-related receptor containing LDLR class A rep... 254 4e-67
gi|17149834 sortilin 1 preproprotein [Homo sapiens] 226 1e-58
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ... 42 0.004
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ... 42 0.004
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens] 42 0.004
gi|239754797 PREDICTED: hypothetical protein [Homo sapiens] 40 0.013
gi|239749325 PREDICTED: hypothetical protein [Homo sapiens] 40 0.013
gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo ... 40 0.013
gi|239743415 PREDICTED: hypothetical protein [Homo sapiens] 40 0.013
gi|239509122 PREDICTED: hypothetical protein [Homo sapiens] 40 0.013
gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo sa... 38 0.049
gi|239753975 PREDICTED: hypothetical protein [Homo sapiens] 36 0.24
gi|41352718 deltex homolog 1 [Homo sapiens] 36 0.24
gi|4503657 forkhead box H1 [Homo sapiens] 35 0.32
gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens] 35 0.32
gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens] 35 0.32
gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens] 35 0.32
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 35 0.42
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 35 0.42
gi|34577118 dopey family member 1 [Homo sapiens] 35 0.42
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 35 0.55
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens] 35 0.55
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens] 35 0.55
gi|169164783 PREDICTED: hypothetical protein [Homo sapiens] 35 0.55
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens] 35 0.55
gi|169163482 PREDICTED: hypothetical protein [Homo sapiens] 35 0.55
>gi|61743973 SORCS receptor 1 isoform a [Homo sapiens]
Length = 1168
Score = 2374 bits (6153), Expect = 0.0
Identities = 1168/1168 (100%), Positives = 1168/1168 (100%)
Query: 1 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG 60
MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG
Sbjct: 1 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG 60
Query: 61 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER 120
RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER
Sbjct: 61 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER 120
Query: 121 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW 180
GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW
Sbjct: 121 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW 180
Query: 181 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK 240
SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK
Sbjct: 181 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK 240
Query: 241 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA 300
RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA
Sbjct: 241 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA 300
Query: 301 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ 360
EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ
Sbjct: 301 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ 360
Query: 361 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE 420
PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE
Sbjct: 361 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE 420
Query: 421 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL 480
NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL
Sbjct: 421 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL 480
Query: 481 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI 540
ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI
Sbjct: 481 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI 540
Query: 541 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM 600
IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM
Sbjct: 541 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM 600
Query: 601 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL 660
KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL
Sbjct: 601 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL 660
Query: 661 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP 720
VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP
Sbjct: 661 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP 720
Query: 721 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG 780
CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG
Sbjct: 721 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG 780
Query: 781 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG 840
VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG
Sbjct: 781 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG 840
Query: 841 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV 900
IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV
Sbjct: 841 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV 900
Query: 901 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG 960
TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG
Sbjct: 901 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG 960
Query: 961 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI 1020
NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI
Sbjct: 961 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI 1020
Query: 1021 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL 1080
LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL
Sbjct: 1021 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL 1080
Query: 1081 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVALPSPPSPSTQPGD 1140
VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVALPSPPSPSTQPGD
Sbjct: 1081 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVALPSPPSPSTQPGD 1140
Query: 1141 SSLRLQRARHATPPSTPKRGSAGAQYAI 1168
SSLRLQRARHATPPSTPKRGSAGAQYAI
Sbjct: 1141 SSLRLQRARHATPPSTPKRGSAGAQYAI 1168
>gi|61743975 SORCS receptor 1 isoform b [Homo sapiens]
Length = 1198
Score = 2289 bits (5931), Expect = 0.0
Identities = 1124/1126 (99%), Positives = 1126/1126 (100%)
Query: 1 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG 60
MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG
Sbjct: 1 MGKVGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG 60
Query: 61 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER 120
RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER
Sbjct: 61 RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAER 120
Query: 121 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW 180
GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW
Sbjct: 121 GEGASRSPRGVLRDGGQQEPGTRERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHW 180
Query: 181 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK 240
SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK
Sbjct: 181 SGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK 240
Query: 241 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA 300
RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA
Sbjct: 241 RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSA 300
Query: 301 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ 360
EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ
Sbjct: 301 EFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQ 360
Query: 361 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE 420
PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE
Sbjct: 361 PFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDE 420
Query: 421 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL 480
NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL
Sbjct: 421 NQVFAAVQEWNQNDTYNLYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFL 480
Query: 481 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI 540
ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI
Sbjct: 481 ANKKIDNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGI 540
Query: 541 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM 600
IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM
Sbjct: 541 IASKDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAM 600
Query: 601 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL 660
KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL
Sbjct: 601 KHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQL 660
Query: 661 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP 720
VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP
Sbjct: 661 VKVDYKSIFDRRCAEEDYRPWQLHSQGEACIMGAKRIYKKRKSERKCMQGKYAGAMESEP 720
Query: 721 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG 780
CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG
Sbjct: 721 CVCTEADFDCDYGYERHSNGQCLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDG 780
Query: 781 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG 840
VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG
Sbjct: 781 VREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDG 840
Query: 841 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV 900
IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV
Sbjct: 841 IAVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFV 900
Query: 901 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG 960
TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG
Sbjct: 901 TTKNKEVNATAVLWPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAG 960
Query: 961 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI 1020
NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI
Sbjct: 961 NAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHI 1020
Query: 1021 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL 1080
LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL
Sbjct: 1021 LVAVLPGLPTTAELFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVL 1080
Query: 1081 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRV 1126
VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKR++
Sbjct: 1081 VHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKI 1126
>gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo sapiens]
Length = 1222
Score = 1521 bits (3938), Expect = 0.0
Identities = 727/1036 (70%), Positives = 858/1036 (82%), Gaps = 2/1036 (0%)
Query: 93 RGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGTRER-DPDKAT 151
RG G RR R ERG+ + +P R G+RE +A
Sbjct: 115 RGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPLAKGSREEVKAPRAG 174
Query: 152 RFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRST 211
E+LRL ST+FALTGDSAHNQAMVHWSGHNSSVILILTKLYD+NLGS+TESSLWRST
Sbjct: 175 GSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLYDFNLGSVTESSLWRST 234
Query: 212 DYGTTYEKLNDKVGLKTILSYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLN 271
DYGTTYEKLNDKVGLKT+LSYLYV PTNKRKIMLL+DPE+ESS+LISSDEGATYQKYRL
Sbjct: 235 DYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMESSILISSDEGATYQKYRLT 294
Query: 272 FYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDL 331
FYIQSLLFHPKQEDW+LAYS DQKLYSS +FGRRWQL+ E + PNRFYWSV G +KE DL
Sbjct: 295 FYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHERITPNRFYWSVAGLDKEADL 354
Query: 332 VHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGGRPHYY 391
VH+E RT DG++HYLTCR+Q C E R+ PF ID SL+VQD Y+F+Q+T+ GR YY
Sbjct: 355 VHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYY 414
Query: 392 VSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLA 451
VSYRR AFAQ+KLPKY+LPKDMH+ISTDENQVFAAVQEWNQNDTYNLYISDTRG+YFTLA
Sbjct: 415 VSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLA 474
Query: 452 LENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDTDL 511
+EN++SSRG GNI+I+LYEVAGIKG+FLANKK+D+QVKT+ITYNKGRDWRLLQAPD DL
Sbjct: 475 MENIKSSRGLMGNIIIELYEVAGIKGIFLANKKVDDQVKTYITYNKGRDWRLLQAPDVDL 534
Query: 512 RGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSELSDTDISMFVS 571
RG PVHCLLP+CSLHLHL++SENPY+SG I+SK+TAP ++VA+GNIG ELS TDI +F+S
Sbjct: 535 RGSPVHCLLPFCSLHLHLQLSENPYSSGRISSKETAPGLVVATGNIGPELSYTDIGVFIS 594
Query: 572 SDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLF 631
SD GNTWRQIF+EE++V +LD GG LVAMKHT LP+RHLW+SFDEG SW KY FTS+PLF
Sbjct: 595 SDGGNTWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLF 654
Query: 632 VDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQGEACI 691
VDG L E G ET IMTVFGHFS RSEWQLVKVDYKSIF R C +EDY+ W L +QGE C+
Sbjct: 655 VDGALVEAGMETHIMTVFGHFSLRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCV 714
Query: 692 MGAKRIYKKRKSERKCMQGK-YAGAMESEPCVCTEADFDCDYGYERHSNGQCLPAFWFNP 750
MG ++I+KKRK +C G+ ++G++ SEPCVC DF+CDYGYERH QC+PAFW+NP
Sbjct: 715 MGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYERHGESQCVPAFWYNP 774
Query: 751 SSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLT 810
+S SKDCSLGQSYLNSTGYR++VSNNCTDG+RE+YTAK Q CPGKAPRGL +VT DG+L
Sbjct: 775 ASPSKDCSLGQSYLNSTGYRRIVSNNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLV 834
Query: 811 AEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMEDGIKHVYQNVGIFRVTVQ 870
AEQGHN T ++ +EEGD+QRT IQ+DFGDGIAVSY N S +EDGIKHVY++ GIF+VT
Sbjct: 835 AEQGHNATFIILMEEGDLQRTNIQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAY 894
Query: 871 VDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPSQVGTLTYVWWYGNN 930
+N+LGSD+AVL+LHV CP+EHVHL +PFV +NKEVN +AV+WPSQ+GTLTY WW+GN+
Sbjct: 895 AENNLGSDTAVLFLHVVCPVEHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNS 954
Query: 931 TEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLSFSPNLDDY 990
T+PLITL+ SISF F +EG +TITVQV+AGNA++QDTK IAV+E F+S LSFSPNLD +
Sbjct: 955 TKPLITLDSSISFTFLAEGTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYH 1014
Query: 991 NPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLPYQDPAGENKRST 1050
NPDIPEWR+DIG VIK++LV+ T VP IL+AV PGLPT+AELF+LP ++ K +
Sbjct: 1015 NPDIPEWRKDIGNVIKRALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNE 1074
Query: 1051 DDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVV 1110
DLEQI E L + LNQN V FELKPGV+V+V+ LT APLVD + HS SAMLMLLSVV
Sbjct: 1075 GDLEQIVETLFNALNQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVV 1134
Query: 1111 FVGLAVFVIYKFKRRV 1126
FVGLAVF+IYKFKR++
Sbjct: 1135 FVGLAVFLIYKFKRKI 1150
>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
Length = 1159
Score = 970 bits (2507), Expect = 0.0
Identities = 504/1112 (45%), Positives = 710/1112 (63%), Gaps = 37/1112 (3%)
Query: 33 GGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERA 92
G G +P P + P P R+P + PL++ L A G S E
Sbjct: 12 GPGPTARAPSPGAPP--------------PPRSPRSR-PLLLLLLLLGACGAAGRSPEPG 56
Query: 93 R-GTGASMAVAARS---GRRRRSGADQEKAERGE----GASRSPRGVLRDGGQQEPGTR- 143
R G A + RS GR G + +A E G S P + G G R
Sbjct: 57 RLGPHAQLTRVPRSPPAGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRR 116
Query: 144 -ERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSI 202
ER A ++ L ST+F L GD+ HNQAMVHW+G NSSVILILTK Y ++G +
Sbjct: 117 WERAAPLAGVASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKV 176
Query: 203 TESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNKRKIMLLTDP--EIESSLLISSD 260
ESSLWRS+D+GT+Y KL + G+ T++ Y+CPTNKRK++L++ + + SL +S+D
Sbjct: 177 LESSLWRSSDFGTSYTKLTLQPGVTTVIDNFYICPTNKRKVILVSSSLSDRDQSLFLSAD 236
Query: 261 EGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYW 320
EGAT+QK + F++++L+FHPK+ED +LAY+++ KLY S++ G++W L+QE V + +W
Sbjct: 237 EGATFQKQPIPFFVETLIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQERVTKDHVFW 296
Query: 321 SVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFV 380
SV G + +PDLVH+EA+ + G Y+TC + NC+E PF G ID SL VQD Y+F
Sbjct: 297 SVSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFF 356
Query: 381 QLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYI 440
+ TS + YYVSYRRN F MKLPKYALPKD+ +ISTDE+QVF AVQEW Q DTYNLY
Sbjct: 357 KATSANQTKYYVSYRRNEFVLMKLPKYALPKDLQIISTDESQVFVAVQEWYQMDTYNLYQ 416
Query: 441 SDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRD 500
SD RGV + L L++V+SSR E +++ID+ EV G+KG+FLAN+KID +V T ITYNKGRD
Sbjct: 417 SDPRGVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVMTLITYNKGRD 476
Query: 501 WRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSE 560
W L+ P D+ G P +C P C LHLHL+ ++NPY SG + +KDTAP +I+ +GN+GS+
Sbjct: 477 WDYLRPPSMDMNGKPTNCKPPDCHLHLHLRWADNPYVSGTVHTKDTAPGLIMGAGNLGSQ 536
Query: 561 LSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSW 620
L + M+++SD G+TWRQ+FEEEH +LYLD GGV+VA+K TS+P++ L S DEG +W
Sbjct: 537 LVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEGLTW 596
Query: 621 SKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSHRSEWQLVKVDYKSIFDRRCAEEDYRP 680
S ++FTS +FVDG+L EPG+ETL+MTVFGH S RS+W+LVKVD++ F R+C EEDY
Sbjct: 597 STHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFRPSFSRQCGEEDYSS 656
Query: 681 WQLHS-QGEACIMGAKRIYKKRKSERKCMQGK-YAGAMESEPCVCTEADFDCDYGYERHS 738
W+L + QG+ CIMG +R ++KRKS C++G+ + A+ S C C ++DF CDYG+ER S
Sbjct: 657 WELSNLQGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDFLCDYGFERSS 716
Query: 739 NGQ-----CLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCP 793
+ + C FWFNP S DC+LGQ+Y +S GYRKVVSN C GV Q + +CP
Sbjct: 717 SSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDMQQSQVQLQCP 776
Query: 794 GKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGIAVSYVNLSSMED 853
PRGL++ + G +V +V+ E+GDV T QVD GDG YVNL+ +
Sbjct: 777 LTPPRGLQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGE 836
Query: 854 GIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVL 913
I+H Y++ GI+RV+V+ +N+ G D AVL++ V PL+ ++L + V N+EVN TAVL
Sbjct: 837 PIRHRYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLTAVL 896
Query: 914 WPSQVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVY 973
P + WW G++ +PL++L+ S++ RF+ G +TVQ + GN++LQD++ + V
Sbjct: 897 LPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVLRVL 956
Query: 974 EEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAE 1033
++F+ + L FS LD YNP+ PEWR D+G V+ + L + T VP + ++ V PGLPT A+
Sbjct: 957 DQFQVMPLQFSKELDAYNPNTPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPTLAD 1016
Query: 1034 LFVLPYQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVD 1093
L+VL P KRS ++++ + LN + F L+ GVRVLV A T
Sbjct: 1017 LYVL-LPPPRPTRKRSLSSDKRLAAIQ-QVLNAQKISFLLRGGVRVLV-ALRDTGTGAEQ 1073
Query: 1094 LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRR 1125
L A+++L + F++YKFKR+
Sbjct: 1074 LGGGGGYWAVVVLFVIGLFAAGAFILYKFKRK 1105
>gi|4507157 sortilin-related receptor containing LDLR class A
repeats preproprotein [Homo sapiens]
Length = 2214
Score = 254 bits (648), Expect = 4e-67
Identities = 184/668 (27%), Positives = 330/668 (49%), Gaps = 57/668 (8%)
Query: 170 DSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGL--- 226
+ +HNQ +VHW+G S+VI+ L + L S ++ S DYG +++K++DK+
Sbjct: 99 NDSHNQMVVHWAGEKSNVIVALAR-DSLALARPKSSDVYVSYDYGKSFKKISDKLNFGLG 157
Query: 227 ---KTILSYLYVCPTNKRKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQ 283
+ +++ Y P + ++ + L I+ D T Q + + F LL H K
Sbjct: 158 NRSEAVIAQFYHSPADNKRYIFAD--AYAQYLWITFDFCNTLQGFSIPFRAADLLLHSKA 215
Query: 284 EDWILAYSQ---DQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVD 340
+ +L + + +++L+ S +FG+ W +IQE V F W + +K P+ +++E
Sbjct: 216 SNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHV--KSFSWGIDPYDK-PNTIYIERHEPS 272
Query: 341 GHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVF----VQLTSGGRP---HYYVS 393
G+S R + ++ NQ + ++D Y+F V L + +VS
Sbjct: 273 GYSTVF--RSTDFFQSRENQEVI-LEEVRDFQLRDKYMFATKVVHLLGSEQQSSVQLWVS 329
Query: 394 YRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYNLYISDTRGVYFTLALE 453
+ R + + ++ E+QVF V + N+ NLYIS+ G+ F+L+LE
Sbjct: 330 FGRKPMRAAQFVTRHPINEYYIADASEDQVFVCVS--HSNNRTNLYISEAEGLKFSLSLE 387
Query: 454 NV--QSSRGPEGNIMI---------DLYEVAGIKGMFLAN----KKIDNQVKTFITYNKG 498
NV S G + ++ D + V G++G+++A + +++ IT++KG
Sbjct: 388 NVLYYSPGGAGSDTLVRYFANEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKG 447
Query: 499 RDWRLLQAPDTDLRGDPVHCLLPY-CSLHLHLKVSE--NPYTSGI-IASKDTAPSIIVAS 554
W LQAP G+ ++C L CSLHL ++S+ N + I SK++AP +I+A+
Sbjct: 448 GTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLRRMPILSKESAPGLIIAT 507
Query: 555 GNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSF 614
G++G L+ + ++++SS AG WR+ H + D GG++ A+ + L S
Sbjct: 508 GSVGKNLA-SKTNVYISSSAGARWREALPGPHYYTWGDHGGIITAIAQ-GMETNELKYST 565
Query: 615 DEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG-HFSHRSEWQLVKVDYKSIFDRRC 673
+EG +W + F+ P+FV G+L EPGE++ + T+FG + + W +++V+ C
Sbjct: 566 NEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIFGSNKENVHSWLILQVNATDALGVPC 625
Query: 674 AEEDYRPWQ-LHSQGEACIMGAKRIYKKRKSERKCMQGK-YAGAMESEPCVCTEADFDCD 731
E DY+ W +G C++G K ++K+R C G+ + + C CT D++CD
Sbjct: 626 TENDYKLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECD 685
Query: 732 YGY---ERHSNGQCLPAFWFNPSSLSK--DCSLGQSYLNSTGYRKVVSNNCTDG-VREQY 785
+G+ E S C+P F+ S S C +G +Y + GYRK+ + C+ G V +
Sbjct: 686 FGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGSTYRRTRGYRKISGDTCSGGDVEARL 745
Query: 786 TAKPQKCP 793
+ CP
Sbjct: 746 EGELVPCP 753
>gi|17149834 sortilin 1 preproprotein [Homo sapiens]
Length = 831
Score = 226 bits (576), Expect = 1e-58
Identities = 169/678 (24%), Positives = 316/678 (46%), Gaps = 54/678 (7%)
Query: 146 DPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLY-DYNLGSITE 204
+ ++ R R +L + T D + W G ++ VIL+LT + + + +
Sbjct: 82 EDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLVIMTFGQ 141
Query: 205 SSLWRSTDYGTTYEKLNDKVGLKTILSY--LYVCPTNKRKIMLLTDPEIESS---LLISS 259
S L+RS DYG ++ + D + I + + + P N K++L + S + SS
Sbjct: 142 SKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSS 201
Query: 260 DEGATYQKYRLNFY-IQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNR- 317
D + + L F+ + +++ P+ D++LA S + L+ S FG +W+ I + V +
Sbjct: 202 DFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKW 261
Query: 318 ------FYWSVMGSNKEPDLVHLEA-RTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDS 370
F+ + + + DL LE RT D + T ++ S
Sbjct: 262 GSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIGVKIY----------------S 305
Query: 371 LIVQDHYVFVQLTSGG---RPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAV 427
+ ++F + + R + + + + ++ +LP + +++ +++ VF V
Sbjct: 306 FGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHV 365
Query: 428 QEWNQNDTYNLYISDTRGVYFTLALE-NVQSSRGPEGNIMIDLYEVAGIKGMFLANK-KI 485
E ++ SD RG+ ++ +L+ ++ ++ G E D V ++G+++ +
Sbjct: 366 DEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGE----TDFTNVTSLRGVYITSVLSE 421
Query: 486 DNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIA--S 543
DN ++T IT+++G W L+ P+ D CSLH+H S + + +A S
Sbjct: 422 DNSIQTMITFDQGGRWTHLRKPENS-ECDATAKNKNECSLHIHASYSISQKLNVPMAPLS 480
Query: 544 KDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHT 603
+ A I++A G++G +S +++S D G +W ++ E H LD GG++VA++H+
Sbjct: 481 EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS 540
Query: 604 SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSH--RSEWQLV 661
S PI + S DEG+ W Y+FT P++ G+ EPG ++ ++++G S+W
Sbjct: 541 SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY 600
Query: 662 KVDYKSIFDRRCAEEDYRPWQLHSQG-----EACIMGAKRIYKKRKSERKCMQGK-YAGA 715
+D+K I +R C E+DY W HS + CI+G K + + + C G+ Y
Sbjct: 601 TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT 660
Query: 716 MESEPCVCTEADFDCDYGYERHSN-GQCLPAFWFNPSSLSKDCSLG-QSYLNSTGYRKVV 773
+ C+C+ DF CD+GY R N +C+ L + C G + +L + GYRK+
Sbjct: 661 KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDL-EFCLYGREEHLTTNGYRKIP 719
Query: 774 SNNCTDGVREQYTAKPQK 791
+ C GV K K
Sbjct: 720 GDKCQGGVNPVREVKDLK 737
>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
sapiens]
Length = 384
Score = 41.6 bits (96), Expect = 0.004
Identities = 46/157 (29%), Positives = 61/157 (38%), Gaps = 15/157 (9%)
Query: 28 APGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRP----------L 77
+P G +PHP S R A+ P + PGR+ + V P L
Sbjct: 60 SPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPSQHQSGSRL 119
Query: 78 FSVAPGDR-ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGG 136
APG R S RA A+ AAR+ R + RG+G+ + R GG
Sbjct: 120 RPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGG 179
Query: 137 QQEPGTRER---DPDKATR-FRMEELRLTSTTFALTG 169
Q P T R P ++ R FR L L S + TG
Sbjct: 180 QPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTG 216
>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
sapiens]
Length = 384
Score = 41.6 bits (96), Expect = 0.004
Identities = 46/157 (29%), Positives = 61/157 (38%), Gaps = 15/157 (9%)
Query: 28 APGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRP----------L 77
+P G +PHP S R A+ P + PGR+ + V P L
Sbjct: 60 SPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPSQHQSGSRL 119
Query: 78 FSVAPGDR-ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGG 136
APG R S RA A+ AAR+ R + RG+G+ + R GG
Sbjct: 120 RPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGG 179
Query: 137 QQEPGTRER---DPDKATR-FRMEELRLTSTTFALTG 169
Q P T R P ++ R FR L L S + TG
Sbjct: 180 QPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTG 216
>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
Length = 384
Score = 41.6 bits (96), Expect = 0.004
Identities = 46/157 (29%), Positives = 61/157 (38%), Gaps = 15/157 (9%)
Query: 28 APGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRP----------L 77
+P G +PHP S R A+ P + PGR+ + V P L
Sbjct: 60 SPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPSQHQSGSRL 119
Query: 78 FSVAPGDR-ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGG 136
APG R S RA A+ AAR+ R + RG+G+ + R GG
Sbjct: 120 RPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGG 179
Query: 137 QQEPGTRER---DPDKATR-FRMEELRLTSTTFALTG 169
Q P T R P ++ R FR L L S + TG
Sbjct: 180 QPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTG 216
>gi|239754797 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 40.0 bits (92), Expect = 0.013
Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Query: 29 PGVCGGGSCCPSPHPSSA-PRSASTPRGF--SHQGRPGRAPATPLPLVVRPLFSVAPGDR 85
PGV G + + H S+A P + RG QG PG LP + R G R
Sbjct: 3 PGVGVGAAGLGAAHRSTAAPGRGVSVRGTVGRQQGGPGHGNVDHLPNLGRQ--PRGAGSR 60
Query: 86 ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE--PGT 142
S RA TGA+ V +SG R + + + E GE +R R GG++E PGT
Sbjct: 61 GASAPRAVRTGAAPEVVVQSGHRSHA-SKRRFLEEGEAPARRLSERRRGGGKEESRPGT 118
>gi|239749325 PREDICTED: hypothetical protein [Homo sapiens]
Length = 155
Score = 40.0 bits (92), Expect = 0.013
Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Query: 29 PGVCGGGSCCPSPHPSSA-PRSASTPRGF--SHQGRPGRAPATPLPLVVRPLFSVAPGDR 85
PGV G + + H S+A P + RG QG PG LP + R G R
Sbjct: 3 PGVGVGAAGLGAAHRSTAAPGRGVSVRGTVGRQQGGPGHGNVDHLPNLGRQ--PRGAGSR 60
Query: 86 ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE--PGT 142
S RA TGA+ V +SG R + + + E GE +R R GG++E PGT
Sbjct: 61 GASAPRAVRTGAAPEVVVQSGHRSHA-SKRRFLEEGEAPARRLSERRRGGGKEESRPGT 118
>gi|239749199 PREDICTED: hypothetical protein XP_002346952 [Homo
sapiens]
Length = 209
Score = 40.0 bits (92), Expect = 0.013
Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 11/129 (8%)
Query: 28 APGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRP----------L 77
+P G +PHP S R A+ P + PGR+ + V P L
Sbjct: 60 SPESAAGTEVSGAPHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPSQHQSGSRL 119
Query: 78 FSVAPGDR-ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGG 136
APG R S RA A+ AAR+ R + RG+G+ + R GG
Sbjct: 120 RPAAPGPRPGCSSARASPAPAAPQAAARTAPGRAASGGSGPGSRGQGSDQVGARPSRAGG 179
Query: 137 QQEPGTRER 145
Q P T R
Sbjct: 180 QPPPLTCRR 188
>gi|239743415 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 40.0 bits (92), Expect = 0.013
Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Query: 29 PGVCGGGSCCPSPHPSSA-PRSASTPRGF--SHQGRPGRAPATPLPLVVRPLFSVAPGDR 85
PGV G + + H S+A P + RG QG PG LP + R G R
Sbjct: 3 PGVGVGAAGLGAAHRSTAAPGRGVSVRGTVGRQQGGPGHGNVDHLPNLGRQ--PRGAGSR 60
Query: 86 ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE--PGT 142
S RA TGA+ V +SG R + + + E GE +R R GG++E PGT
Sbjct: 61 GASAPRAVRTGAAPEVVVQSGHRSHA-SKRRFLEEGEAPARRLSERRRGGGKEESRPGT 118
>gi|239509122 PREDICTED: hypothetical protein [Homo sapiens]
Length = 155
Score = 40.0 bits (92), Expect = 0.013
Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Query: 29 PGVCGGGSCCPSPHPSSA-PRSASTPRGF--SHQGRPGRAPATPLPLVVRPLFSVAPGDR 85
PGV G + + H S+A P + RG QG PG LP + R G R
Sbjct: 3 PGVGVGAAGLGAAHRSTAAPGRGVSVRGTVGRQQGGPGHGNVDHLPNLGRQ--PRGAGSR 60
Query: 86 ALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE--PGT 142
S RA TGA+ V +SG R + + + E GE +R R GG++E PGT
Sbjct: 61 GASAPRAVRTGAAPEVVVQSGHRSHA-SKRRFLEEGEAPARRLSERRRGGGKEESRPGT 118
>gi|21389423 junctional sarcoplasmic reticulum protein 1 [Homo
sapiens]
Length = 331
Score = 38.1 bits (87), Expect = 0.049
Identities = 43/143 (30%), Positives = 55/143 (38%), Gaps = 7/143 (4%)
Query: 12 ARLSALLAGAGLLILCA-PGVCGGGSCCPSPH--PSSAPRSASTP-RGFSHQGRPGRAPA 67
A L ALL A L A PG + P P PSSAPR S+P F Q P PA
Sbjct: 131 ASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPA 190
Query: 68 TPLPLVVRPLFSVAPGDRALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRS 127
VRP PG R + G + A R R + ++ R EG R
Sbjct: 191 PRAEAEVRPKI---PGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRK 247
Query: 128 PRGVLRDGGQQEPGTRERDPDKA 150
+ + ++E +E P A
Sbjct: 248 EKPRKEERPKKERPRKEERPRAA 270
>gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]
Length = 389
Score = 35.8 bits (81), Expect = 0.24
Identities = 29/97 (29%), Positives = 37/97 (38%), Gaps = 5/97 (5%)
Query: 39 PSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGAS 98
P P P S P + R RP R P +VV LF V R ++ R G
Sbjct: 177 PRPQPPSRPAAQPPSRPAFRSPRPVRGPHPRRAVVVAVLFGVQAPRRDVAEGGLRRDGRR 236
Query: 99 MAVAARSGRRR-----RSGADQEKAERGEGASRSPRG 130
+A + GR A ++ G G SR PRG
Sbjct: 237 PGLAPQRGRGGLLLVVLHAATVQRPRLGRGPSRPPRG 273
>gi|41352718 deltex homolog 1 [Homo sapiens]
Length = 620
Score = 35.8 bits (81), Expect = 0.24
Identities = 33/97 (34%), Positives = 38/97 (39%), Gaps = 14/97 (14%)
Query: 5 GAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQG---- 60
G G R SA GA L AP G P+P P + PRS P G G
Sbjct: 240 GPPGALAVRPSATFTGAALW--AAPAA---GPAEPAPPPGAPPRSPGAPGGARTPGQNNL 294
Query: 61 -RPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTG 96
RPG T V S+ PG AL ++ GTG
Sbjct: 295 NRPGPQRTTS----VSARASIPPGVPALPVKNLNGTG 327
>gi|4503657 forkhead box H1 [Homo sapiens]
Length = 365
Score = 35.4 bits (80), Expect = 0.32
Identities = 19/49 (38%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 34 GGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAP 82
GGS +P P AP+S+ P G + G P PLP RPL+ + P
Sbjct: 174 GGSGEGAPWPGLAPQSSPVPAGTGNSGEEA-VPTPPLPSSERPLWPLCP 221
>gi|36287060 K(lysine) acetyltransferase 5 isoform 3 [Homo sapiens]
Length = 461
Score = 35.4 bits (80), Expect = 0.32
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 11/90 (12%)
Query: 48 RSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPG-----DRALSLERARGTGASMAVA 102
+ A TP + G PG P +P V R + V+P + A + + A AVA
Sbjct: 73 KEAKTP---TKNGLPGSRPGSPEREVKRKVEVVSPATPVPSETAPASVFPQNGAARRAVA 129
Query: 103 ARSGRRRRS---GADQEKAERGEGASRSPR 129
A+ GR+R+S G D++ + +G +PR
Sbjct: 130 AQPGRKRKSNCLGTDEDSQDSSDGIPSAPR 159
>gi|4503247 ribosomal RNA processing 1 homolog [Homo sapiens]
Length = 461
Score = 35.4 bits (80), Expect = 0.32
Identities = 26/68 (38%), Positives = 36/68 (52%), Gaps = 7/68 (10%)
Query: 85 RALSLERARGTGA----SMAVAARSGRRRRSGADQE-KAERGEGASRSPRGVLRD--GGQ 137
R L L++ RG G S + + RRR GAD E +AE GE + R +LRD G+
Sbjct: 366 RLLRLQQERGKGEKEPPSPGMERKRSRRRGVGADPEARAEAGEQPGTAERALLRDQPRGR 425
Query: 138 QEPGTRER 145
+ G R+R
Sbjct: 426 GQRGARQR 433
>gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
Length = 1729
Score = 35.4 bits (80), Expect = 0.32
Identities = 34/112 (30%), Positives = 41/112 (36%), Gaps = 15/112 (13%)
Query: 41 PHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERARGTGASMA 100
PHP A T S PGR PA P P G + L LE +S A
Sbjct: 1421 PHP--ADPGMETGEALSFGASPGRCPARPPP----------SGSQGL-LEEMLAASSSKA 1467
Query: 101 VAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGTRERDPDKATR 152
VA R SG E G GA + VL G P R + +A++
Sbjct: 1468 VARRES--AASGLGGLLEEEGAGAGAAQEEVLEPGRDSPPSWRPQPDGEASQ 1517
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 35.0 bits (79), Expect = 0.42
Identities = 36/133 (27%), Positives = 48/133 (36%), Gaps = 9/133 (6%)
Query: 18 LAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPL 77
L G +L P GGG S P + + + R PA P+ L RP
Sbjct: 512 LPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPG 571
Query: 78 FSVAPGDRALSLERA-------RGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRG 130
PG L E RG A + GRR R+G+D + G+ + RG
Sbjct: 572 PVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRG 631
Query: 131 VLRDGGQQEPGTR 143
DG PG +
Sbjct: 632 F--DGLAGLPGEK 642
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 35.0 bits (79), Expect = 0.42
Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 83 GDRALSLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPGT 142
G LER GAS RS RRRRSG D G G +R+P GV Q T
Sbjct: 3 GSAVTVLERG---GASSPAERRSKRRRRSGGD----GGGGGGARAPEGVRAPAAGQPRAT 55
Query: 143 RERDPDKAT 151
+ P T
Sbjct: 56 KGAPPPPGT 64
>gi|34577118 dopey family member 1 [Homo sapiens]
Length = 2465
Score = 35.0 bits (79), Expect = 0.42
Identities = 46/216 (21%), Positives = 93/216 (43%), Gaps = 31/216 (14%)
Query: 934 LITLEGSISFRFTSEGMNTITVQVSAGNAILQDTKTIAVYEEFRSLRLSFSPNLDDYNPD 993
L+ L SIS + T+ + AI +D K +++ E L+ ++ P+
Sbjct: 1859 LVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKKHLSL--EVCMLQFFYAYIQRIPVPN 1916
Query: 994 IPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLPYQDPAGENKRSTDDL 1053
+ + + ++K S+ + PGQ +++ VL F++ ++P+ ENK+ DL
Sbjct: 1917 LVDSWASLLILLKDSIQLSLPAPGQFLILGVL-------NEFIM--KNPSLENKKDQRDL 1967
Query: 1054 EQISELLI--------HTLNQNS---VHFELKPGVRVLVHAAHL---------TAAPLVD 1093
+ ++ ++ +L Q + + E+KP +++V +L A +
Sbjct: 1968 QDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETAN 2027
Query: 1094 LTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVALP 1129
+TP+ L LLS V L V Y ++ +P
Sbjct: 2028 ITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIP 2063
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 34.7 bits (78), Expect = 0.55
Identities = 30/104 (28%), Positives = 37/104 (35%), Gaps = 17/104 (16%)
Query: 39 PSPHPSSAPRSASTPRGF---SHQGRPGRAPATPLPLVVRPLFSVAPGDRALSLERARGT 95
P P P P P G +H G PA PLP P G
Sbjct: 176 PPPPPGPPPPPGLPPSGVPAAAHGAGGGPPPAPPLPAAQGP--------------GGGGA 221
Query: 96 GASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQE 139
GA AA +G + R + QE+A G A ++ G GG E
Sbjct: 222 GAPGLAAAIAGAKLRKVSKQEEASGGPTAPKAESGRSGGGGLME 265
>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 34.7 bits (78), Expect = 0.55
Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 16/114 (14%)
Query: 33 GGGSCCPSPH-----PSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRAL 87
GGG PSP PS PR T S + GRA + RP A
Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP--------HAA 259
Query: 88 SLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPG 141
+RG GA+ +V+A + R R GA + R +G +R LR G PG
Sbjct: 260 VRNSSRGRGAATSVSA-AARPTRGGARGHR--RADGRARGGCAQLRAGTPSAPG 310
>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 34.7 bits (78), Expect = 0.55
Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 16/114 (14%)
Query: 33 GGGSCCPSPH-----PSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRAL 87
GGG PSP PS PR T S + GRA + RP A
Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP--------HAA 259
Query: 88 SLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPG 141
+RG GA+ +V+A + R R GA + R +G +R LR G PG
Sbjct: 260 VRNSSRGRGAATSVSA-AARPTRGGARGHR--RADGRARGGCAQLRAGTPSAPG 310
>gi|169164783 PREDICTED: hypothetical protein [Homo sapiens]
Length = 396
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 9/116 (7%)
Query: 30 GVCGG-GSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPG-DRAL 87
GV GG G P P + R H GR GR PL L+V P + G DR
Sbjct: 71 GVGGGVGGAQPGSVPLGQHLALERGRTLGH-GRVGRRDPPPLGLLVNPRVAGVDGLDRGG 129
Query: 88 SLERAR-GTGASMAVAARSGRRRRSGADQ-----EKAERGEGASRSPRGVLRDGGQ 137
L+ A G + V +GR+RR+ Q + G G +R RG + GQ
Sbjct: 130 RLDPAGIGQVLGLGVLGGAGRQRRALGGQALGLLAQVGIGAGHARGGRGAVGPAGQ 185
>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
Length = 373
Score = 34.7 bits (78), Expect = 0.55
Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 16/114 (14%)
Query: 33 GGGSCCPSPH-----PSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPGDRAL 87
GGG PSP PS PR T S + GRA + RP A
Sbjct: 208 GGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP--------HAA 259
Query: 88 SLERARGTGASMAVAARSGRRRRSGADQEKAERGEGASRSPRGVLRDGGQQEPG 141
+RG GA+ +V+A + R R GA + R +G +R LR G PG
Sbjct: 260 VRNSSRGRGAATSVSA-AARPTRGGARGHR--RADGRARGGCAQLRAGTPSAPG 310
>gi|169163482 PREDICTED: hypothetical protein [Homo sapiens]
Length = 396
Score = 34.7 bits (78), Expect = 0.55
Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 9/116 (7%)
Query: 30 GVCGG-GSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPATPLPLVVRPLFSVAPG-DRAL 87
GV GG G P P + R H GR GR PL L+V P + G DR
Sbjct: 71 GVGGGVGGAQPGSVPLGQHLALERGRTLGH-GRVGRRDPPPLGLLVNPRVAGVDGLDRGG 129
Query: 88 SLERAR-GTGASMAVAARSGRRRRSGADQ-----EKAERGEGASRSPRGVLRDGGQ 137
L+ A G + V +GR+RR+ Q + G G +R RG + GQ
Sbjct: 130 RLDPAGIGQVLGLGVLGGAGRQRRALGGQALGLLAQVGIGAGHARGGRGAVGPAGQ 185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,370,247
Number of Sequences: 37866
Number of extensions: 2342743
Number of successful extensions: 9450
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 132
Number of HSP's that attempted gapping in prelim test: 9177
Number of HSP's gapped (non-prelim): 369
length of query: 1168
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1055
effective length of database: 13,968,660
effective search space: 14736936300
effective search space used: 14736936300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.