Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 13540600

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13540600 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform B [Homo sapiens]
         (345 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan...   673   0.0  
gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan...   611   e-175
gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]     339   2e-93
gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]       339   2e-93
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [...    60   4e-09
gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [...    60   4e-09
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    60   4e-09
gi|224451082 cytospin A [Homo sapiens]                                 58   1e-08
gi|224451080 cytospin A [Homo sapiens]                                 58   1e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    57   3e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    57   3e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    57   3e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    57   3e-08
gi|16262452 cingulin [Homo sapiens]                                    55   9e-08
gi|157743265 caspase recruitment domain family, member 11 [Homo ...    55   9e-08
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]                 54   2e-07
gi|169217489 PREDICTED: similar to phosphodiesterase 4D interact...    53   3e-07
gi|34878904 synaptonemal complex protein 1 [Homo sapiens]              53   3e-07
gi|32698688 citron [Homo sapiens]                                      52   6e-07
gi|148746195 trichohyalin [Homo sapiens]                               52   8e-07
gi|119120918 coiled-coil domain containing 64 [Homo sapiens]           52   1e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     51   1e-06
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]                   51   1e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             51   2e-06
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         51   2e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    51   2e-06
gi|149363685 hypothetical protein LOC23379 [Homo sapiens]              50   2e-06
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]           50   2e-06
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]            50   2e-06
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     50   2e-06

>gi|13540600 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform B [Homo sapiens]
          Length = 345

 Score =  673 bits (1736), Expect = 0.0
 Identities = 345/345 (100%), Positives = 345/345 (100%)

Query: 1   MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ 60
           MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ
Sbjct: 1   MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ 60

Query: 61  RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
           RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ
Sbjct: 61  RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120

Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
           ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE
Sbjct: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180

Query: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG 240
           LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG
Sbjct: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG 240

Query: 241 TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG 300
           TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG
Sbjct: 241 TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG 300

Query: 301 TKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV 345
           TKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV
Sbjct: 301 TKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV 345


>gi|71284108 nudE nuclear distribution gene E homolog (A.
           nidulans)-like 1 isoform A [Homo sapiens]
          Length = 328

 Score =  611 bits (1576), Expect = e-175
 Identities = 315/315 (100%), Positives = 315/315 (100%)

Query: 1   MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ 60
           MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ
Sbjct: 1   MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ 60

Query: 61  RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
           RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ
Sbjct: 61  RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120

Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
           ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE
Sbjct: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180

Query: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG 240
           LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG
Sbjct: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG 240

Query: 241 TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG 300
           TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG
Sbjct: 241 TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG 300

Query: 301 TKFSRSGHTSFFDKG 315
           TKFSRSGHTSFFDKG
Sbjct: 301 TKFSRSGHTSFFDKG 315


>gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]
          Length = 335

 Score =  339 bits (870), Expect = 2e-93
 Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%)

Query: 9   FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68
           FSS +EE  YWK+L++ YKQ  +  ++EL EFQEGSRE EAELE QL Q E RNRDL ++
Sbjct: 8   FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67

Query: 69  NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
           N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA
Sbjct: 68  NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127

Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
           KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q
Sbjct: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186

Query: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243
           E  R   PSS  ++ E+ D+AVQA+ S+P+TP+  +G  ++  +P +   G     G +P
Sbjct: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244

Query: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285
           LTP+ARISALNIVGDLLRKVGALESKLA+CRN   DQ+  ++
Sbjct: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286


>gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
          Length = 335

 Score =  339 bits (870), Expect = 2e-93
 Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%)

Query: 9   FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68
           FSS +EE  YWK+L++ YKQ  +  ++EL EFQEGSRE EAELE QL Q E RNRDL ++
Sbjct: 8   FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67

Query: 69  NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
           N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA
Sbjct: 68  NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127

Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
           KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q
Sbjct: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186

Query: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243
           E  R   PSS  ++ E+ D+AVQA+ S+P+TP+  +G  ++  +P +   G     G +P
Sbjct: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244

Query: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285
           LTP+ARISALNIVGDLLRKVGALESKLA+CRN   DQ+  ++
Sbjct: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286


>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
           [Homo sapiens]
          Length = 969

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 52/182 (28%), Positives = 95/182 (52%), Gaps = 17/182 (9%)

Query: 36  ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
           + V+F E +     E E Q   + + N++L+   Q+L+ E++   ++L    A+ Y ++ 
Sbjct: 374 QCVQFVEAAAH---ESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR 430

Query: 96  VLEDD---LSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAF 152
             E +   L+ + + KEQL +  REL Q  D+ ++   A  + LE   QR++   ++   
Sbjct: 431 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIH---DKAVA 487

Query: 153 LESELDEKESLLVSVQRLKDEARDLRQ-ELAVRERQQEVTR-KSAPSSPTLDCEKMDSAV 210
           LE  +DEK S       L+++ ++LRQ  LAVRER  ++ R +   SS     + M+S +
Sbjct: 488 LERAIDEKFS------ALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLL 541

Query: 211 QA 212
           +A
Sbjct: 542 RA 543



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 39/186 (20%), Positives = 74/186 (39%), Gaps = 20/186 (10%)

Query: 27  KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYE----------- 75
           KQ    + +  +  Q  S    AEL+ ++ Q E  N+ LQ     + YE           
Sbjct: 220 KQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQ 279

Query: 76  ---VEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
              ++ LKE L+ +  ++ +   V+E        ++E LH+   +L Q +     +    
Sbjct: 280 DGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ--SQLGQLHSSEGTSPAQQ 337

Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVS----VQRLKDEARDLRQELAVRERQQ 188
            V+L D +  L  +      L+  + +KE  L      VQ ++  A +  Q+     +  
Sbjct: 338 QVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHN 397

Query: 189 EVTRKS 194
           +  RK+
Sbjct: 398 QELRKA 403


>gi|50658071 phosphodiesterase 4D interacting protein isoform 5
           [Homo sapiens]
          Length = 1132

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 52/182 (28%), Positives = 95/182 (52%), Gaps = 17/182 (9%)

Query: 36  ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
           + V+F E +     E E Q   + + N++L+   Q+L+ E++   ++L    A+ Y ++ 
Sbjct: 537 QCVQFVEAAAH---ESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR 593

Query: 96  VLEDD---LSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAF 152
             E +   L+ + + KEQL +  REL Q  D+ ++   A  + LE   QR++   ++   
Sbjct: 594 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIH---DKAVA 650

Query: 153 LESELDEKESLLVSVQRLKDEARDLRQ-ELAVRERQQEVTR-KSAPSSPTLDCEKMDSAV 210
           LE  +DEK S       L+++ ++LRQ  LAVRER  ++ R +   SS     + M+S +
Sbjct: 651 LERAIDEKFS------ALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLL 704

Query: 211 QA 212
           +A
Sbjct: 705 RA 706



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 39/186 (20%), Positives = 74/186 (39%), Gaps = 20/186 (10%)

Query: 27  KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYE----------- 75
           KQ    + +  +  Q  S    AEL+ ++ Q E  N+ LQ     + YE           
Sbjct: 383 KQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQ 442

Query: 76  ---VEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
              ++ LKE L+ +  ++ +   V+E        ++E LH+   +L Q +     +    
Sbjct: 443 DGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ--SQLGQLHSSEGTSPAQQ 500

Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVS----VQRLKDEARDLRQELAVRERQQ 188
            V+L D +  L  +      L+  + +KE  L      VQ ++  A +  Q+     +  
Sbjct: 501 QVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHN 560

Query: 189 EVTRKS 194
           +  RK+
Sbjct: 561 QELRKA 566


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
           [Homo sapiens]
          Length = 2346

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 52/182 (28%), Positives = 95/182 (52%), Gaps = 17/182 (9%)

Query: 36  ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
           + V+F E +     E E Q   + + N++L+   Q+L+ E++   ++L    A+ Y ++ 
Sbjct: 374 QCVQFVEAAAH---ESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR 430

Query: 96  VLEDD---LSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAF 152
             E +   L+ + + KEQL +  REL Q  D+ ++   A  + LE   QR++   ++   
Sbjct: 431 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIH---DKAVA 487

Query: 153 LESELDEKESLLVSVQRLKDEARDLRQ-ELAVRERQQEVTR-KSAPSSPTLDCEKMDSAV 210
           LE  +DEK S       L+++ ++LRQ  LAVRER  ++ R +   SS     + M+S +
Sbjct: 488 LERAIDEKFS------ALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLL 541

Query: 211 QA 212
           +A
Sbjct: 542 RA 543



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 7/107 (6%)

Query: 62   NRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQA 121
            NR LQA    +  E     E L      S   +  LE +L   +  ++QL + +RE +Q 
Sbjct: 1911 NRRLQAQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQE 1970

Query: 122  NDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ 168
                   +    +SL++ + RL   +     L+ + +EK+ L  S+Q
Sbjct: 1971 VLHFREER----LSLQENDSRLQHKL---VLLQQQCEEKQQLFESLQ 2010



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 1/115 (0%)

Query: 17   AYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEV 76
            A    +S ++ Q  +  R+ L+  +   +ELE ELE Q V+ +Q   DL+   Q + +  
Sbjct: 1916 AQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFR 1975

Query: 77   EALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            E      E+     +K V +L+    + + + E L   ++  E    + ++  +A
Sbjct: 1976 EERLSLQENDSRLQHKLV-LLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKA 2029



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 39/186 (20%), Positives = 74/186 (39%), Gaps = 20/186 (10%)

Query: 27  KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYE----------- 75
           KQ    + +  +  Q  S    AEL+ ++ Q E  N+ LQ     + YE           
Sbjct: 220 KQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQ 279

Query: 76  ---VEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
              ++ LKE L+ +  ++ +   V+E        ++E LH+   +L Q +     +    
Sbjct: 280 DGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ--SQLGQLHSSEGTSPAQQ 337

Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVS----VQRLKDEARDLRQELAVRERQQ 188
            V+L D +  L  +      L+  + +KE  L      VQ ++  A +  Q+     +  
Sbjct: 338 QVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHN 397

Query: 189 EVTRKS 194
           +  RK+
Sbjct: 398 QELRKA 403


>gi|224451082 cytospin A [Homo sapiens]
          Length = 1117

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 60/267 (22%), Positives = 119/267 (44%), Gaps = 39/267 (14%)

Query: 10  SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
           SSL+E+ A+ +  + + + +  +  DE   FQE +++   +L   L +      + + + 
Sbjct: 624 SSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETER 683

Query: 70  QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE---------- 119
             +K  +  L++++E   A       ++ D  +  + +++Q H   RE++          
Sbjct: 684 SDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREES 743

Query: 120 ----QANDDLERA-------KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ 168
               Q   DL+ A       K      + D ++RL++A E+N  L  EL+E +S     +
Sbjct: 744 AEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEE 803

Query: 169 --RLKDEARDLRQELAVRERQQEVTRKSAPSS---PTLD--CEKMDSAVQ----ASLSLP 217
             R+ +    + ++LA   +   ++R+S+ SS   PT+    +  DSA Q    A+ ++P
Sbjct: 804 RGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIP 863

Query: 218 ATPVGKGTENTFPSPKAIPNGFGTSPL 244
            TP+        PSP   P     SP+
Sbjct: 864 RTPLS-------PSPMKTPPAAAVSPM 883



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 28/179 (15%)

Query: 27  KQSFQEARDELVEFQEGSRELE----------AELEAQLVQAEQRNRDLQADNQRLKYEV 76
           +Q  +EA++ +   +E S  +E          A L A L + +      Q +  RLK ++
Sbjct: 524 EQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQL 583

Query: 77  EALKEKLEHQYA-QSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ----ANDDLERAKRA 131
           E  K+K+   Y+  +    S ++D L   R  KE+       L++      +D  R + A
Sbjct: 584 ENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDA 643

Query: 132 TIVSLED----FEQRLNQAIE-RNAFLE---SELDEKES----LLVSVQRLKDEARDLR 178
            I  +ED    F++   + IE  N  LE   S+LDEKE+    +  ++  L+DE    R
Sbjct: 644 -IAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHR 701


>gi|224451080 cytospin A [Homo sapiens]
          Length = 1117

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 60/267 (22%), Positives = 119/267 (44%), Gaps = 39/267 (14%)

Query: 10  SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
           SSL+E+ A+ +  + + + +  +  DE   FQE +++   +L   L +      + + + 
Sbjct: 624 SSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETER 683

Query: 70  QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE---------- 119
             +K  +  L++++E   A       ++ D  +  + +++Q H   RE++          
Sbjct: 684 SDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREES 743

Query: 120 ----QANDDLERA-------KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ 168
               Q   DL+ A       K      + D ++RL++A E+N  L  EL+E +S     +
Sbjct: 744 AEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEE 803

Query: 169 --RLKDEARDLRQELAVRERQQEVTRKSAPSS---PTLD--CEKMDSAVQ----ASLSLP 217
             R+ +    + ++LA   +   ++R+S+ SS   PT+    +  DSA Q    A+ ++P
Sbjct: 804 RGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIP 863

Query: 218 ATPVGKGTENTFPSPKAIPNGFGTSPL 244
            TP+        PSP   P     SP+
Sbjct: 864 RTPLS-------PSPMKTPPAAAVSPM 883



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 28/179 (15%)

Query: 27  KQSFQEARDELVEFQEGSRELE----------AELEAQLVQAEQRNRDLQADNQRLKYEV 76
           +Q  +EA++ +   +E S  +E          A L A L + +      Q +  RLK ++
Sbjct: 524 EQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQL 583

Query: 77  EALKEKLEHQYA-QSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ----ANDDLERAKRA 131
           E  K+K+   Y+  +    S ++D L   R  KE+       L++      +D  R + A
Sbjct: 584 ENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDA 643

Query: 132 TIVSLED----FEQRLNQAIE-RNAFLE---SELDEKES----LLVSVQRLKDEARDLR 178
            I  +ED    F++   + IE  N  LE   S+LDEKE+    +  ++  L+DE    R
Sbjct: 644 -IAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHR 701


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 11/202 (5%)

Query: 11   SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
            +L EET   +    + +Q   +A +EL E  E  +  +A L+      E+ N DL  + +
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1241

Query: 71   RL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRA-IKEQLHKYVRELEQANDDLE 126
             L   K EVE  K+KLE Q  +   + S    D  + RA + +++HK   E+E     L 
Sbjct: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCS----DGERARAELNDKVHKLQNEVESVTGMLN 1297

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
             A+   I   +D     +Q  +    L+ E  +K ++   +++L++E   L+ +L   + 
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL---DE 1354

Query: 187  QQEVTRKSAPSSPTLDCEKMDS 208
            + E  +       TL+ +  DS
Sbjct: 1355 EMEAKQNLERHISTLNIQLSDS 1376



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 9/184 (4%)

Query: 10   SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQ 66
            S L EE    +E      + + EA +  V      +ELE    E+EA+L + E R + LQ
Sbjct: 883  SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 942

Query: 67   ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
            A+ +++  ++  L+E+LE + A   K    L+ +     A  ++L   +  ++  N+ L 
Sbjct: 943  AERKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLS 998

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ-RLKDEARDLRQELAVRE 185
            + ++     + D    L +  E+   L    ++ ES++  ++ RLK E +  RQEL   +
Sbjct: 999  KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK 1057

Query: 186  RQQE 189
            R+ E
Sbjct: 1058 RKLE 1061



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 51/225 (22%)

Query: 20   KELSLKYK----QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK-- 73
            K +S KY     ++  EAR++  +    +R LE  LEA+  + E+ N+ L+A+ + L   
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1519

Query: 74   --------YEVEALKEKLEHQYAQSYKQVSVLEDDLSQT--------------------- 104
                    +E+E  K  LE Q  +   Q+  LED+L  T                     
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579

Query: 105  ------------RAIKEQLHKYVRELEQANDD---LERAKRATIVSLEDFEQRLNQAIER 149
                        R ++ QLH+Y  ELE           AK+     L+D E + + AI+ 
Sbjct: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639

Query: 150  NAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKS 194
                  +L + ++ +   QR  ++AR  R E+    ++ E   KS
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 11/202 (5%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
            LK+E    +EL    ++   +A D    F E   +L+A++    +Q  ++  +LQA   R
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASD----FHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            L  E+ A K     +  +    +S L++DL   RA + +  K  R+L +  + L+     
Sbjct: 1099 LDDEI-AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157

Query: 132  TIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEV 190
            T+ S    ++   +  +    L+  LDE+  S    VQ ++ +     +EL   E+ ++ 
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT--EQLEQF 1215

Query: 191  TRKSA---PSSPTLDCEKMDSA 209
             R  A    +  TL+ E  D A
Sbjct: 1216 KRAKANLDKNKQTLEKENADLA 1237



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 5/176 (2%)

Query: 14   EETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK 73
            + TA  +EL  K +Q     +  L E          E+  +  QA +   +     +R K
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219

Query: 74   YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
              ++  K+ LE + A    ++ VL     +    K++L   V+EL+    D ERA+    
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR---- 1275

Query: 134  VSLEDFEQRLNQAIERNAFLESELDEKE-SLLVSVQRLKDEARDLRQELAVRERQQ 188
              L D   +L   +E    + +E + K   L   V  L  + +D ++ L    RQ+
Sbjct: 1276 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)

Query: 33   ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYK 92
            +RDE+    + + +    LEA L+Q ++   DL A  +R + + +  KE+L  + A S  
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQE---DLAA-AERARKQADLEKEELAEELASSLS 1722

Query: 93   QVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKR---------ATIVSLEDF 139
              + L+D+  +  A    ++E+L +    +E  +D + +A +         AT  S    
Sbjct: 1723 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1782

Query: 140  EQRLNQAIER-NAFLESELDEKESLLVS-----VQRLKDEARDLRQELAVRERQQEVTRK 193
             +   Q +ER N  L S+L E E  + S     +  L+ +   L +++    R+++   K
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1842

Query: 194  S 194
            S
Sbjct: 1843 S 1843



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 49/214 (22%), Positives = 95/214 (44%), Gaps = 44/214 (20%)

Query: 4    EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQL-----VQA 58
            ++I + +   EE A   +   K K   Q+  D+LV   +  R+L + LE +      + A
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458

Query: 59   EQRNRDLQADNQRLKYEVEAL-KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
            E++N   +  ++R + E EA  KE      A++ ++    +++L +T    + L   + +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAEMED 1515

Query: 118  LEQANDD-------LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-------- 162
            L  + DD       LE++KRA    +E+              ++++L+E E         
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEE--------------MKTQLEELEDELQATEDA 1561

Query: 163  ---LLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
               L V++Q LK +     ++L  R+ Q E  R+
Sbjct: 1562 KLRLEVNMQALKGQ---FERDLQARDEQNEEKRR 1592



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 32/185 (17%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADN 69
            +E+     +L  K++    E    L + ++  +ELE    +LE       ++  DLQA  
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078

Query: 70   QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER-- 127
              LK ++   +E+L+   A+       L+D+++Q    K    K +RELE    DL+   
Sbjct: 1079 AELKMQLAKKEEELQAALAR-------LDDEIAQ----KNNALKKIRELEGHISDLQEDL 1127

Query: 128  -AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
             ++RA     E  ++ L + +E    L++EL++      + Q L+             +R
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEA---LKTELEDTLDSTATQQELR------------AKR 1172

Query: 187  QQEVT 191
            +QEVT
Sbjct: 1173 EQEVT 1177



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 19/196 (9%)

Query: 8    DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAE----- 59
            D   L+E+ A  +    +     +E  +EL     G   L+ E   LEA++ Q E     
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747

Query: 60   -QRNRDLQADNQR-LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
             Q N +  +D  R    + E L  +L  + + + K  S  +    Q + ++ +LH    E
Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH----E 1803

Query: 118  LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
            +E A   ++   ++TI +LE    +L + +E+ A    +    +SL    ++LK+    +
Sbjct: 1804 MEGA---VKSKFKSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKLKEILLQV 1858

Query: 178  RQELAVRERQQEVTRK 193
              E  + E+ +E   K
Sbjct: 1859 EDERKMAEQYKEQAEK 1874



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 19/178 (10%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
            L+EET     +S K +Q  +E R+ L +      +L+ E+EA+        ++L+     
Sbjct: 1324 LQEETRQKLNVSTKLRQ-LEEERNSLQD------QLDEEMEAK--------QNLERHIST 1368

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            L  ++   K+KL+  +A +   V  LE+   + +   E L +   E   A D LE+ K  
Sbjct: 1369 LNIQLSDSKKKLQ-DFAST---VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424

Query: 132  TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
                L+D    L+   +  + LE +  + + LL   + +  +  D R       R++E
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 22/102 (21%), Positives = 47/102 (46%)

Query: 86  QYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQ 145
           Q  +  +++   ED+L +T+  +++    ++ELEQ +  L   K      L+   +   +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905

Query: 146 AIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
           A E    L ++  E E +L  ++   +E  D  Q+L    ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 33/173 (19%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE-----------AELEAQLV---- 56
            L  E A  +  + K + + Q+   +  E +    E+E           A LEA++     
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828

Query: 57   QAEQRNRDLQADNQRLKYEVEALKEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
            Q EQ  R+ QA  + LK + + LKE L     E + A+ YK+ +  E   ++ + +K QL
Sbjct: 1829 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--EKGNARVKQLKRQL 1886

Query: 112  HKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
             +   E ++ N +  + +R            L++A E N  +  E++  +S L
Sbjct: 1887 EEAEEESQRINANRRKLQR-----------ELDEATESNEAMGREVNALKSKL 1928



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 45/178 (25%), Positives = 86/178 (48%), Gaps = 34/178 (19%)

Query: 28   QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
            +  +E    + + QE   +L++E  A+  +AE++ RDL         E+EALK +LE   
Sbjct: 1111 KKIRELEGHISDLQE---DLDSERAARN-KAEKQKRDLGE-------ELEALKTELEDTL 1159

Query: 88   ----------AQSYKQVSVL-----EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
                      A+  ++V+VL     E+  S    ++E   K+ + +E+  + LE+ KRA 
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219

Query: 133  IVSLEDFEQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 186
              +L+  +Q L    + NA L  EL      K+ +    ++L+ + ++L+ + +  ER
Sbjct: 1220 -ANLDKNKQTLE---KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1273



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           LK     W  L  K K   Q  R E  E Q    EL+   E Q  +AE   ++L+  + +
Sbjct: 827 LKLRNWQWWRLFTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQ-KAENELKELEQKHSQ 884

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
           L  E   L+E+L+ +  + Y +   +   L+   A K++L + + E+E            
Sbjct: 885 LTEEKNLLQEQLQAE-TELYAEAEEMRVRLA---AKKQELEEILHEME------------ 928

Query: 132 TIVSLEDFEQRLNQ-AIERNAFLESELDEKESL-LVSVQRLKDEARDLRQELAVRERQQE 189
               LE+ E R  Q   ER    +  LD +E L      R K +   +  E  +++ + E
Sbjct: 929 --ARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986

Query: 190 V 190
           +
Sbjct: 987 I 987



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 9/117 (7%)

Query: 68   DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLE 126
            D Q L  E    K  +  +  Q  ++ + L+D L +    K+ L +++  L  Q +D  +
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378

Query: 127  RAK--RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
            + +   +T+ +LE+ ++R  + IE    L  + +EK +    +++ K+    L+QEL
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIEN---LTQQYEEKAAAYDKLEKTKNR---LQQEL 1429


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 11/202 (5%)

Query: 11   SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
            +L EET   +    + +Q   +A +EL E  E  +  +A L+      E+ N DL  + +
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1248

Query: 71   RL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRA-IKEQLHKYVRELEQANDDLE 126
             L   K EVE  K+KLE Q  +   + S    D  + RA + +++HK   E+E     L 
Sbjct: 1249 VLGQAKQEVEHKKKKLEAQVQELQSKCS----DGERARAELNDKVHKLQNEVESVTGMLN 1304

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
             A+   I   +D     +Q  +    L+ E  +K ++   +++L++E   L+ +L   + 
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL---DE 1361

Query: 187  QQEVTRKSAPSSPTLDCEKMDS 208
            + E  +       TL+ +  DS
Sbjct: 1362 EMEAKQNLERHISTLNIQLSDS 1383



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 9/184 (4%)

Query: 10   SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQ 66
            S L EE    +E      + + EA +  V      +ELE    E+EA+L + E R + LQ
Sbjct: 890  SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 949

Query: 67   ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
            A+ +++  ++  L+E+LE + A   K    L+ +     A  ++L   +  ++  N+ L 
Sbjct: 950  AERKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLS 1005

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ-RLKDEARDLRQELAVRE 185
            + ++     + D    L +  E+   L    ++ ES++  ++ RLK E +  RQEL   +
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK 1064

Query: 186  RQQE 189
            R+ E
Sbjct: 1065 RKLE 1068



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 51/225 (22%)

Query: 20   KELSLKYK----QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK-- 73
            K +S KY     ++  EAR++  +    +R LE  LEA+  + E+ N+ L+A+ + L   
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1526

Query: 74   --------YEVEALKEKLEHQYAQSYKQVSVLEDDLSQT--------------------- 104
                    +E+E  K  LE Q  +   Q+  LED+L  T                     
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1586

Query: 105  ------------RAIKEQLHKYVRELEQANDD---LERAKRATIVSLEDFEQRLNQAIER 149
                        R ++ QLH+Y  ELE           AK+     L+D E + + AI+ 
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646

Query: 150  NAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKS 194
                  +L + ++ +   QR  ++AR  R E+    ++ E   KS
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 11/202 (5%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
            LK+E    +EL    ++   +A D    F E   +L+A++    +Q  ++  +LQA   R
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASD----FHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            L  E+ A K     +  +    +S L++DL   RA + +  K  R+L +  + L+     
Sbjct: 1106 LDDEI-AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164

Query: 132  TIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEV 190
            T+ S    ++   +  +    L+  LDE+  S    VQ ++ +     +EL   E+ ++ 
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT--EQLEQF 1222

Query: 191  TRKSA---PSSPTLDCEKMDSA 209
             R  A    +  TL+ E  D A
Sbjct: 1223 KRAKANLDKNKQTLEKENADLA 1244



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 5/176 (2%)

Query: 14   EETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK 73
            + TA  +EL  K +Q     +  L E          E+  +  QA +   +     +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 74   YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
              ++  K+ LE + A    ++ VL     +    K++L   V+EL+    D ERA+    
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR---- 1282

Query: 134  VSLEDFEQRLNQAIERNAFLESELDEKE-SLLVSVQRLKDEARDLRQELAVRERQQ 188
              L D   +L   +E    + +E + K   L   V  L  + +D ++ L    RQ+
Sbjct: 1283 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)

Query: 33   ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYK 92
            +RDE+    + + +    LEA L+Q ++   DL A  +R + + +  KE+L  + A S  
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQE---DLAA-AERARKQADLEKEELAEELASSLS 1729

Query: 93   QVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKR---------ATIVSLEDF 139
              + L+D+  +  A    ++E+L +    +E  +D + +A +         AT  S    
Sbjct: 1730 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1789

Query: 140  EQRLNQAIER-NAFLESELDEKESLLVS-----VQRLKDEARDLRQELAVRERQQEVTRK 193
             +   Q +ER N  L S+L E E  + S     +  L+ +   L +++    R+++   K
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1849

Query: 194  S 194
            S
Sbjct: 1850 S 1850



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 49/214 (22%), Positives = 95/214 (44%), Gaps = 44/214 (20%)

Query: 4    EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQL-----VQA 58
            ++I + +   EE A   +   K K   Q+  D+LV   +  R+L + LE +      + A
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465

Query: 59   EQRNRDLQADNQRLKYEVEAL-KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
            E++N   +  ++R + E EA  KE      A++ ++    +++L +T    + L   + +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAEMED 1522

Query: 118  LEQANDD-------LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-------- 162
            L  + DD       LE++KRA    +E+              ++++L+E E         
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEE--------------MKTQLEELEDELQATEDA 1568

Query: 163  ---LLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
               L V++Q LK +     ++L  R+ Q E  R+
Sbjct: 1569 KLRLEVNMQALKGQ---FERDLQARDEQNEEKRR 1599



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 32/185 (17%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADN 69
            +E+     +L  K++    E    L + ++  +ELE    +LE       ++  DLQA  
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085

Query: 70   QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER-- 127
              LK ++   +E+L+   A+       L+D+++Q    K    K +RELE    DL+   
Sbjct: 1086 AELKMQLAKKEEELQAALAR-------LDDEIAQ----KNNALKKIRELEGHISDLQEDL 1134

Query: 128  -AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
             ++RA     E  ++ L + +E    L++EL++      + Q L+             +R
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEA---LKTELEDTLDSTATQQELR------------AKR 1179

Query: 187  QQEVT 191
            +QEVT
Sbjct: 1180 EQEVT 1184



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 19/196 (9%)

Query: 8    DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAE----- 59
            D   L+E+ A  +    +     +E  +EL     G   L+ E   LEA++ Q E     
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754

Query: 60   -QRNRDLQADNQR-LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
             Q N +  +D  R    + E L  +L  + + + K  S  +    Q + ++ +LH    E
Sbjct: 1755 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH----E 1810

Query: 118  LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
            +E A   ++   ++TI +LE    +L + +E+ A    +    +SL    ++LK+    +
Sbjct: 1811 MEGA---VKSKFKSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKLKEILLQV 1865

Query: 178  RQELAVRERQQEVTRK 193
              E  + E+ +E   K
Sbjct: 1866 EDERKMAEQYKEQAEK 1881



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 19/178 (10%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
            L+EET     +S K +Q  +E R+ L +      +L+ E+EA+        ++L+     
Sbjct: 1331 LQEETRQKLNVSTKLRQ-LEEERNSLQD------QLDEEMEAK--------QNLERHIST 1375

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            L  ++   K+KL+  +A +   V  LE+   + +   E L +   E   A D LE+ K  
Sbjct: 1376 LNIQLSDSKKKLQ-DFAST---VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431

Query: 132  TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
                L+D    L+   +  + LE +  + + LL   + +  +  D R       R++E
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 22/102 (21%), Positives = 47/102 (46%)

Query: 86  QYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQ 145
           Q  +  +++   ED+L +T+  +++    ++ELEQ +  L   K      L+   +   +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912

Query: 146 AIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
           A E    L ++  E E +L  ++   +E  D  Q+L    ++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 33/173 (19%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE-----------AELEAQLV---- 56
            L  E A  +  + K + + Q+   +  E +    E+E           A LEA++     
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835

Query: 57   QAEQRNRDLQADNQRLKYEVEALKEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
            Q EQ  R+ QA  + LK + + LKE L     E + A+ YK+ +  E   ++ + +K QL
Sbjct: 1836 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--EKGNARVKQLKRQL 1893

Query: 112  HKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
             +   E ++ N +  + +R            L++A E N  +  E++  +S L
Sbjct: 1894 EEAEEESQRINANRRKLQR-----------ELDEATESNEAMGREVNALKSKL 1935



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 45/178 (25%), Positives = 86/178 (48%), Gaps = 34/178 (19%)

Query: 28   QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
            +  +E    + + QE   +L++E  A+  +AE++ RDL         E+EALK +LE   
Sbjct: 1118 KKIRELEGHISDLQE---DLDSERAARN-KAEKQKRDLGE-------ELEALKTELEDTL 1166

Query: 88   ----------AQSYKQVSVL-----EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
                      A+  ++V+VL     E+  S    ++E   K+ + +E+  + LE+ KRA 
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 133  IVSLEDFEQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 186
              +L+  +Q L    + NA L  EL      K+ +    ++L+ + ++L+ + +  ER
Sbjct: 1227 -ANLDKNKQTLE---KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1280



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           LK     W  L  K K   Q  R E  E Q    EL+   E Q  +AE   ++L+  + +
Sbjct: 834 LKLRNWQWWRLFTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQ-KAENELKELEQKHSQ 891

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
           L  E   L+E+L+ +  + Y +   +   L+   A K++L + + E+E            
Sbjct: 892 LTEEKNLLQEQLQAE-TELYAEAEEMRVRLA---AKKQELEEILHEME------------ 935

Query: 132 TIVSLEDFEQRLNQ-AIERNAFLESELDEKESL-LVSVQRLKDEARDLRQELAVRERQQE 189
               LE+ E R  Q   ER    +  LD +E L      R K +   +  E  +++ + E
Sbjct: 936 --ARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993

Query: 190 V 190
           +
Sbjct: 994 I 994



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 9/117 (7%)

Query: 68   DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLE 126
            D Q L  E    K  +  +  Q  ++ + L+D L +    K+ L +++  L  Q +D  +
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385

Query: 127  RAK--RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
            + +   +T+ +LE+ ++R  + IE    L  + +EK +    +++ K+    L+QEL
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIEN---LTQQYEEKAAAYDKLEKTKNR---LQQEL 1436


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 11/202 (5%)

Query: 11   SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
            +L EET   +    + +Q   +A +EL E  E  +  +A L+      E+ N DL  + +
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1248

Query: 71   RL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRA-IKEQLHKYVRELEQANDDLE 126
             L   K EVE  K+KLE Q  +   + S    D  + RA + +++HK   E+E     L 
Sbjct: 1249 VLGQAKQEVEHKKKKLEAQVQELQSKCS----DGERARAELNDKVHKLQNEVESVTGMLN 1304

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
             A+   I   +D     +Q  +    L+ E  +K ++   +++L++E   L+ +L   + 
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL---DE 1361

Query: 187  QQEVTRKSAPSSPTLDCEKMDS 208
            + E  +       TL+ +  DS
Sbjct: 1362 EMEAKQNLERHISTLNIQLSDS 1383



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 9/184 (4%)

Query: 10   SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQ 66
            S L EE    +E      + + EA +  V      +ELE    E+EA+L + E R + LQ
Sbjct: 890  SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 949

Query: 67   ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
            A+ +++  ++  L+E+LE + A   K    L+ +     A  ++L   +  ++  N+ L 
Sbjct: 950  AERKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLS 1005

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ-RLKDEARDLRQELAVRE 185
            + ++     + D    L +  E+   L    ++ ES++  ++ RLK E +  RQEL   +
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK 1064

Query: 186  RQQE 189
            R+ E
Sbjct: 1065 RKLE 1068



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 51/225 (22%)

Query: 20   KELSLKYK----QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK-- 73
            K +S KY     ++  EAR++  +    +R LE  LEA+  + E+ N+ L+A+ + L   
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1526

Query: 74   --------YEVEALKEKLEHQYAQSYKQVSVLEDDLSQT--------------------- 104
                    +E+E  K  LE Q  +   Q+  LED+L  T                     
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1586

Query: 105  ------------RAIKEQLHKYVRELEQANDD---LERAKRATIVSLEDFEQRLNQAIER 149
                        R ++ QLH+Y  ELE           AK+     L+D E + + AI+ 
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646

Query: 150  NAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKS 194
                  +L + ++ +   QR  ++AR  R E+    ++ E   KS
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 11/202 (5%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
            LK+E    +EL    ++   +A D    F E   +L+A++    +Q  ++  +LQA   R
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASD----FHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            L  E+ A K     +  +    +S L++DL   RA + +  K  R+L +  + L+     
Sbjct: 1106 LDDEI-AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164

Query: 132  TIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEV 190
            T+ S    ++   +  +    L+  LDE+  S    VQ ++ +     +EL   E+ ++ 
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT--EQLEQF 1222

Query: 191  TRKSA---PSSPTLDCEKMDSA 209
             R  A    +  TL+ E  D A
Sbjct: 1223 KRAKANLDKNKQTLEKENADLA 1244



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 5/176 (2%)

Query: 14   EETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK 73
            + TA  +EL  K +Q     +  L E          E+  +  QA +   +     +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 74   YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
              ++  K+ LE + A    ++ VL     +    K++L   V+EL+    D ERA+    
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR---- 1282

Query: 134  VSLEDFEQRLNQAIERNAFLESELDEKE-SLLVSVQRLKDEARDLRQELAVRERQQ 188
              L D   +L   +E    + +E + K   L   V  L  + +D ++ L    RQ+
Sbjct: 1283 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)

Query: 33   ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYK 92
            +RDE+    + + +    LEA L+Q ++   DL A  +R + + +  KE+L  + A S  
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQE---DLAA-AERARKQADLEKEELAEELASSLS 1729

Query: 93   QVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKR---------ATIVSLEDF 139
              + L+D+  +  A    ++E+L +    +E  +D + +A +         AT  S    
Sbjct: 1730 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1789

Query: 140  EQRLNQAIER-NAFLESELDEKESLLVS-----VQRLKDEARDLRQELAVRERQQEVTRK 193
             +   Q +ER N  L S+L E E  + S     +  L+ +   L +++    R+++   K
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1849

Query: 194  S 194
            S
Sbjct: 1850 S 1850



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 49/214 (22%), Positives = 95/214 (44%), Gaps = 44/214 (20%)

Query: 4    EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQL-----VQA 58
            ++I + +   EE A   +   K K   Q+  D+LV   +  R+L + LE +      + A
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465

Query: 59   EQRNRDLQADNQRLKYEVEAL-KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
            E++N   +  ++R + E EA  KE      A++ ++    +++L +T    + L   + +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAEMED 1522

Query: 118  LEQANDD-------LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-------- 162
            L  + DD       LE++KRA    +E+              ++++L+E E         
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEE--------------MKTQLEELEDELQATEDA 1568

Query: 163  ---LLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
               L V++Q LK +     ++L  R+ Q E  R+
Sbjct: 1569 KLRLEVNMQALKGQ---FERDLQARDEQNEEKRR 1599



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 32/185 (17%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADN 69
            +E+     +L  K++    E    L + ++  +ELE    +LE       ++  DLQA  
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085

Query: 70   QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER-- 127
              LK ++   +E+L+   A+       L+D+++Q    K    K +RELE    DL+   
Sbjct: 1086 AELKMQLAKKEEELQAALAR-------LDDEIAQ----KNNALKKIRELEGHISDLQEDL 1134

Query: 128  -AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
             ++RA     E  ++ L + +E    L++EL++      + Q L+             +R
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEA---LKTELEDTLDSTATQQELR------------AKR 1179

Query: 187  QQEVT 191
            +QEVT
Sbjct: 1180 EQEVT 1184



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 19/196 (9%)

Query: 8    DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAE----- 59
            D   L+E+ A  +    +     +E  +EL     G   L+ E   LEA++ Q E     
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754

Query: 60   -QRNRDLQADNQR-LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
             Q N +  +D  R    + E L  +L  + + + K  S  +    Q + ++ +LH    E
Sbjct: 1755 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH----E 1810

Query: 118  LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
            +E A   ++   ++TI +LE    +L + +E+ A    +    +SL    ++LK+    +
Sbjct: 1811 MEGA---VKSKFKSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKLKEILLQV 1865

Query: 178  RQELAVRERQQEVTRK 193
              E  + E+ +E   K
Sbjct: 1866 EDERKMAEQYKEQAEK 1881



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 19/178 (10%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
            L+EET     +S K +Q  +E R+ L +      +L+ E+EA+        ++L+     
Sbjct: 1331 LQEETRQKLNVSTKLRQ-LEEERNSLQD------QLDEEMEAK--------QNLERHIST 1375

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            L  ++   K+KL+  +A +   V  LE+   + +   E L +   E   A D LE+ K  
Sbjct: 1376 LNIQLSDSKKKLQ-DFAST---VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431

Query: 132  TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
                L+D    L+   +  + LE +  + + LL   + +  +  D R       R++E
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 22/102 (21%), Positives = 47/102 (46%)

Query: 86  QYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQ 145
           Q  +  +++   ED+L +T+  +++    ++ELEQ +  L   K      L+   +   +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912

Query: 146 AIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
           A E    L ++  E E +L  ++   +E  D  Q+L    ++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 33/173 (19%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE-----------AELEAQLV---- 56
            L  E A  +  + K + + Q+   +  E +    E+E           A LEA++     
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835

Query: 57   QAEQRNRDLQADNQRLKYEVEALKEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
            Q EQ  R+ QA  + LK + + LKE L     E + A+ YK+ +  E   ++ + +K QL
Sbjct: 1836 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--EKGNARVKQLKRQL 1893

Query: 112  HKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
             +   E ++ N +  + +R            L++A E N  +  E++  +S L
Sbjct: 1894 EEAEEESQRINANRRKLQR-----------ELDEATESNEAMGREVNALKSKL 1935



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 45/178 (25%), Positives = 86/178 (48%), Gaps = 34/178 (19%)

Query: 28   QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
            +  +E    + + QE   +L++E  A+  +AE++ RDL         E+EALK +LE   
Sbjct: 1118 KKIRELEGHISDLQE---DLDSERAARN-KAEKQKRDLGE-------ELEALKTELEDTL 1166

Query: 88   ----------AQSYKQVSVL-----EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
                      A+  ++V+VL     E+  S    ++E   K+ + +E+  + LE+ KRA 
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226

Query: 133  IVSLEDFEQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 186
              +L+  +Q L    + NA L  EL      K+ +    ++L+ + ++L+ + +  ER
Sbjct: 1227 -ANLDKNKQTLE---KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1280



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           LK     W  L  K K   Q  R E  E Q    EL+   E Q  +AE   ++L+  + +
Sbjct: 834 LKLRNWQWWRLFTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQ-KAENELKELEQKHSQ 891

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
           L  E   L+E+L+ +  + Y +   +   L+   A K++L + + E+E            
Sbjct: 892 LTEEKNLLQEQLQAE-TELYAEAEEMRVRLA---AKKQELEEILHEME------------ 935

Query: 132 TIVSLEDFEQRLNQ-AIERNAFLESELDEKESL-LVSVQRLKDEARDLRQELAVRERQQE 189
               LE+ E R  Q   ER    +  LD +E L      R K +   +  E  +++ + E
Sbjct: 936 --ARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993

Query: 190 V 190
           +
Sbjct: 994 I 994



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 9/117 (7%)

Query: 68   DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLE 126
            D Q L  E    K  +  +  Q  ++ + L+D L +    K+ L +++  L  Q +D  +
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385

Query: 127  RAK--RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
            + +   +T+ +LE+ ++R  + IE    L  + +EK +    +++ K+    L+QEL
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIEN---LTQQYEEKAAAYDKLEKTKNR---LQQEL 1436


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 11/202 (5%)

Query: 11   SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
            +L EET   +    + +Q   +A +EL E  E  +  +A L+      E+ N DL  + +
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1241

Query: 71   RL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRA-IKEQLHKYVRELEQANDDLE 126
             L   K EVE  K+KLE Q  +   + S    D  + RA + +++HK   E+E     L 
Sbjct: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCS----DGERARAELNDKVHKLQNEVESVTGMLN 1297

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
             A+   I   +D     +Q  +    L+ E  +K ++   +++L++E   L+ +L   + 
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL---DE 1354

Query: 187  QQEVTRKSAPSSPTLDCEKMDS 208
            + E  +       TL+ +  DS
Sbjct: 1355 EMEAKQNLERHISTLNIQLSDS 1376



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 9/184 (4%)

Query: 10   SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQ 66
            S L EE    +E      + + EA +  V      +ELE    E+EA+L + E R + LQ
Sbjct: 883  SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 942

Query: 67   ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
            A+ +++  ++  L+E+LE + A   K    L+ +     A  ++L   +  ++  N+ L 
Sbjct: 943  AERKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLS 998

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ-RLKDEARDLRQELAVRE 185
            + ++     + D    L +  E+   L    ++ ES++  ++ RLK E +  RQEL   +
Sbjct: 999  KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK 1057

Query: 186  RQQE 189
            R+ E
Sbjct: 1058 RKLE 1061



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 51/225 (22%)

Query: 20   KELSLKYK----QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK-- 73
            K +S KY     ++  EAR++  +    +R LE  LEA+  + E+ N+ L+A+ + L   
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1519

Query: 74   --------YEVEALKEKLEHQYAQSYKQVSVLEDDLSQT--------------------- 104
                    +E+E  K  LE Q  +   Q+  LED+L  T                     
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579

Query: 105  ------------RAIKEQLHKYVRELEQANDD---LERAKRATIVSLEDFEQRLNQAIER 149
                        R ++ QLH+Y  ELE           AK+     L+D E + + AI+ 
Sbjct: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639

Query: 150  NAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKS 194
                  +L + ++ +   QR  ++AR  R E+    ++ E   KS
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 11/202 (5%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
            LK+E    +EL    ++   +A D    F E   +L+A++    +Q  ++  +LQA   R
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASD----FHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            L  E+ A K     +  +    +S L++DL   RA + +  K  R+L +  + L+     
Sbjct: 1099 LDDEI-AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157

Query: 132  TIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEV 190
            T+ S    ++   +  +    L+  LDE+  S    VQ ++ +     +EL   E+ ++ 
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT--EQLEQF 1215

Query: 191  TRKSA---PSSPTLDCEKMDSA 209
             R  A    +  TL+ E  D A
Sbjct: 1216 KRAKANLDKNKQTLEKENADLA 1237



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 5/176 (2%)

Query: 14   EETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK 73
            + TA  +EL  K +Q     +  L E          E+  +  QA +   +     +R K
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219

Query: 74   YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
              ++  K+ LE + A    ++ VL     +    K++L   V+EL+    D ERA+    
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR---- 1275

Query: 134  VSLEDFEQRLNQAIERNAFLESELDEKE-SLLVSVQRLKDEARDLRQELAVRERQQ 188
              L D   +L   +E    + +E + K   L   V  L  + +D ++ L    RQ+
Sbjct: 1276 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)

Query: 33   ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYK 92
            +RDE+    + + +    LEA L+Q ++   DL A  +R + + +  KE+L  + A S  
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQE---DLAA-AERARKQADLEKEELAEELASSLS 1722

Query: 93   QVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKR---------ATIVSLEDF 139
              + L+D+  +  A    ++E+L +    +E  +D + +A +         AT  S    
Sbjct: 1723 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1782

Query: 140  EQRLNQAIER-NAFLESELDEKESLLVS-----VQRLKDEARDLRQELAVRERQQEVTRK 193
             +   Q +ER N  L S+L E E  + S     +  L+ +   L +++    R+++   K
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1842

Query: 194  S 194
            S
Sbjct: 1843 S 1843



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 49/214 (22%), Positives = 95/214 (44%), Gaps = 44/214 (20%)

Query: 4    EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQL-----VQA 58
            ++I + +   EE A   +   K K   Q+  D+LV   +  R+L + LE +      + A
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458

Query: 59   EQRNRDLQADNQRLKYEVEAL-KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
            E++N   +  ++R + E EA  KE      A++ ++    +++L +T    + L   + +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAEMED 1515

Query: 118  LEQANDD-------LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-------- 162
            L  + DD       LE++KRA    +E+              ++++L+E E         
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEE--------------MKTQLEELEDELQATEDA 1561

Query: 163  ---LLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
               L V++Q LK +     ++L  R+ Q E  R+
Sbjct: 1562 KLRLEVNMQALKGQ---FERDLQARDEQNEEKRR 1592



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 32/185 (17%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADN 69
            +E+     +L  K++    E    L + ++  +ELE    +LE       ++  DLQA  
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078

Query: 70   QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER-- 127
              LK ++   +E+L+   A+       L+D+++Q    K    K +RELE    DL+   
Sbjct: 1079 AELKMQLAKKEEELQAALAR-------LDDEIAQ----KNNALKKIRELEGHISDLQEDL 1127

Query: 128  -AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
             ++RA     E  ++ L + +E    L++EL++      + Q L+             +R
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEA---LKTELEDTLDSTATQQELR------------AKR 1172

Query: 187  QQEVT 191
            +QEVT
Sbjct: 1173 EQEVT 1177



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 19/196 (9%)

Query: 8    DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAE----- 59
            D   L+E+ A  +    +     +E  +EL     G   L+ E   LEA++ Q E     
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747

Query: 60   -QRNRDLQADNQR-LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
             Q N +  +D  R    + E L  +L  + + + K  S  +    Q + ++ +LH    E
Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH----E 1803

Query: 118  LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
            +E A   ++   ++TI +LE    +L + +E+ A    +    +SL    ++LK+    +
Sbjct: 1804 MEGA---VKSKFKSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKLKEILLQV 1858

Query: 178  RQELAVRERQQEVTRK 193
              E  + E+ +E   K
Sbjct: 1859 EDERKMAEQYKEQAEK 1874



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 19/178 (10%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
            L+EET     +S K +Q  +E R+ L +      +L+ E+EA+        ++L+     
Sbjct: 1324 LQEETRQKLNVSTKLRQ-LEEERNSLQD------QLDEEMEAK--------QNLERHIST 1368

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            L  ++   K+KL+  +A +   V  LE+   + +   E L +   E   A D LE+ K  
Sbjct: 1369 LNIQLSDSKKKLQ-DFAST---VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424

Query: 132  TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
                L+D    L+   +  + LE +  + + LL   + +  +  D R       R++E
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 22/102 (21%), Positives = 47/102 (46%)

Query: 86  QYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQ 145
           Q  +  +++   ED+L +T+  +++    ++ELEQ +  L   K      L+   +   +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905

Query: 146 AIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
           A E    L ++  E E +L  ++   +E  D  Q+L    ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 33/173 (19%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE-----------AELEAQLV---- 56
            L  E A  +  + K + + Q+   +  E +    E+E           A LEA++     
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828

Query: 57   QAEQRNRDLQADNQRLKYEVEALKEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
            Q EQ  R+ QA  + LK + + LKE L     E + A+ YK+ +  E   ++ + +K QL
Sbjct: 1829 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--EKGNARVKQLKRQL 1886

Query: 112  HKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
             +   E ++ N +  + +R            L++A E N  +  E++  +S L
Sbjct: 1887 EEAEEESQRINANRRKLQR-----------ELDEATESNEAMGREVNALKSKL 1928



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 45/178 (25%), Positives = 86/178 (48%), Gaps = 34/178 (19%)

Query: 28   QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
            +  +E    + + QE   +L++E  A+  +AE++ RDL         E+EALK +LE   
Sbjct: 1111 KKIRELEGHISDLQE---DLDSERAARN-KAEKQKRDLGE-------ELEALKTELEDTL 1159

Query: 88   ----------AQSYKQVSVL-----EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
                      A+  ++V+VL     E+  S    ++E   K+ + +E+  + LE+ KRA 
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219

Query: 133  IVSLEDFEQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 186
              +L+  +Q L    + NA L  EL      K+ +    ++L+ + ++L+ + +  ER
Sbjct: 1220 -ANLDKNKQTLE---KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1273



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           LK     W  L  K K   Q  R E  E Q    EL+   E Q  +AE   ++L+  + +
Sbjct: 827 LKLRNWQWWRLFTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQ-KAENELKELEQKHSQ 884

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
           L  E   L+E+L+ +  + Y +   +   L+   A K++L + + E+E            
Sbjct: 885 LTEEKNLLQEQLQAE-TELYAEAEEMRVRLA---AKKQELEEILHEME------------ 928

Query: 132 TIVSLEDFEQRLNQ-AIERNAFLESELDEKESL-LVSVQRLKDEARDLRQELAVRERQQE 189
               LE+ E R  Q   ER    +  LD +E L      R K +   +  E  +++ + E
Sbjct: 929 --ARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986

Query: 190 V 190
           +
Sbjct: 987 I 987



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 9/117 (7%)

Query: 68   DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLE 126
            D Q L  E    K  +  +  Q  ++ + L+D L +    K+ L +++  L  Q +D  +
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378

Query: 127  RAK--RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
            + +   +T+ +LE+ ++R  + IE    L  + +EK +    +++ K+    L+QEL
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIEN---LTQQYEEKAAAYDKLEKTKNR---LQQEL 1429


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 49/222 (22%), Positives = 94/222 (42%), Gaps = 43/222 (19%)

Query: 8   DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAEL--EAQLVQAEQRNRDL 65
           +     EET +W+ +  K K+  +  + EL++ +    E+E EL  + +++Q E      
Sbjct: 560 ELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARA 619

Query: 66  QADNQRLKYEVEALKEKL---------------------EHQYAQSYKQVSVLEDDLSQT 104
            A + R   +VE LK++L                      H+  +  KQ++VL  +  + 
Sbjct: 620 SAGDTR---QVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRG 676

Query: 105 RAIKEQLHKYVRELEQANDDLERAKRATIV-----------------SLEDFEQRLNQAI 147
           R ++EQ  +  + L+Q   D E A +A +V                 +L + ++  ++  
Sbjct: 677 RELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFR 736

Query: 148 ERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
            R   LE +L E   L+   + ++   RD  Q L   ++Q E
Sbjct: 737 RRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 778



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 1/166 (0%)

Query: 28  QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
           Q  +  + +L E    S+E E  L A     E R  + Q    RL  E + L   LE + 
Sbjct: 768 QRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEG 827

Query: 88  AQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAI 147
            Q         +   Q R +   + +  +ELE+  +D ++A +     LED++++  + +
Sbjct: 828 KQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREV 887

Query: 148 -ERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTR 192
            +     +    E E     + RL+DE + LRQ L   + +++  R
Sbjct: 888 ADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTAR 933



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 32/184 (17%)

Query: 27   KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQ 86
            KQ+ Q+ + +L +++E +R   A+ + Q                RL+ E++ L++ L   
Sbjct: 866  KQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQAL--- 922

Query: 87   YAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQA 146
                  Q S  E D +  R  KE L + ++ LEQ  ++ +R++      L+  E+++++ 
Sbjct: 923  ------QASQAERDTA--RLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSR- 973

Query: 147  IERNAFLESELDEK----ESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLD 202
                  LE+ELDE+    E L   V R +D+   LR EL ++ER          +   L+
Sbjct: 974  ------LETELDEEKNTVELLTDRVNRGRDQVDQLRTEL-MQERS---------ARQDLE 1017

Query: 203  CEKM 206
            C+K+
Sbjct: 1018 CDKI 1021



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 47/188 (25%), Positives = 85/188 (45%), Gaps = 26/188 (13%)

Query: 11  SLKEETAYWKELSLKYKQSFQEARDELVEF--QEGSRELEAELEAQLVQAEQRNRDLQAD 68
           +LKEE A               +RD+ VE   Q+  R+ E +L   +  A Q +  L+A+
Sbjct: 503 ALKEEVA---------------SRDQEVEHVRQQYQRDTE-QLRRSMQDATQDHAVLEAE 546

Query: 69  NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
            Q++   V  L+ +LE    ++    S+ + +    RA K++L +   E E+  ++L   
Sbjct: 547 RQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGE- 605

Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKD-EARDLRQELAVRERQ 187
                  +E  ++ L QA             K+ LL + + LK+ +A    QE+A R R 
Sbjct: 606 ------KIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRD 659

Query: 188 QEVTRKSA 195
           +E+ ++ A
Sbjct: 660 RELEKQLA 667



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 50/204 (24%), Positives = 89/204 (43%), Gaps = 28/204 (13%)

Query: 20  KELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAEQRNRDLQADNQRLKYEV 76
           +E +L+ +++ Q+ R +  E  +     EAE   L  +    E   R+ Q +N   +  +
Sbjct: 680 EEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRI 739

Query: 77  EALKEKLEHQYAQSYKQVSV---LEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
             L+++L+          +V   L D L +  A K+QL + +   ++    L  AKRA  
Sbjct: 740 LGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALE 799

Query: 134 VSLEDF----------EQRLNQAIERNAFL-------ESELDEKESLL-VSVQRLKDE-- 173
             LE+           +Q LN+A+E            ++EL+E++ LL  +V RL  E  
Sbjct: 800 ARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELE 859

Query: 174 --ARDLRQELAVRERQQEVTRKSA 195
               D +Q L   + Q E  ++ A
Sbjct: 860 KIGEDSKQALQQLQAQLEDYKEKA 883



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 38/179 (21%), Positives = 82/179 (45%), Gaps = 29/179 (16%)

Query: 14  EETAYWKELSLKYKQSFQEARDELVEFQ---EGSRELEAELEAQLVQAEQRNRDLQA--- 67
           EE +  +EL  + K   Q++  EL   +   +   +L   LE Q+++ + + + +Q    
Sbjct: 401 EECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEP 460

Query: 68  ----------DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
                     + + L  EV   K+++E Q     ++++ L+  L +  A ++Q  ++VR+
Sbjct: 461 AKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQ 520

Query: 118 LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARD 176
             Q   D E+ +R+           +  A + +A LE+E  +  +L+  +QR  +E  +
Sbjct: 521 --QYQRDTEQLRRS-----------MQDATQDHAVLEAERQKMSALVRGLQRELEETSE 566



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 51/206 (24%), Positives = 92/206 (44%), Gaps = 41/206 (19%)

Query: 33  ARDELVEF--QEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEH----- 85
           +RD+ VE   Q+  R+ E +L   +  A Q +  L+A+ Q++   V  L+ +LE      
Sbjct: 510 SRDQEVEHVRQQYQRDTE-QLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEET 568

Query: 86  -----QYAQSYKQVSVLEDDLSQTRAIKEQLHKYV--------RELEQANDDLERAKRAT 132
                 + ++ + +   + +L Q R  KE++ + +        RELEQA     RA    
Sbjct: 569 GHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQA-----RASAGD 623

Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAV----RERQQ 188
              +E  ++ L +  E    L++E   +E       R +D  R+L ++LAV     +R +
Sbjct: 624 TRQVEVLKKELLRTQEELKELQAERQSQE----VAGRHRD--RELEKQLAVLRVEADRGR 677

Query: 189 EVTRKSAPSSPTL-----DCEKMDSA 209
           E+  ++     TL     DCE+   A
Sbjct: 678 ELEEQNLQLQKTLQQLRQDCEEASKA 703



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 46/188 (24%), Positives = 86/188 (45%), Gaps = 16/188 (8%)

Query: 41   QEGSRELEAELEAQLVQ-----AEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
            +  +  L+ EL AQ +Q     AE + R  Q D  R    +E    +LE +  +    V 
Sbjct: 928  ERDTARLDKELLAQRLQGLEQEAENKKRS-QDDRARQLKGLEEKVSRLETELDEEKNTVE 986

Query: 96   VLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRL--NQAIERNAFL 153
            +L D +++ R   +QL   + +   A  DLE  K +     +D + RL  ++  ++ +  
Sbjct: 987  LLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSAS 1046

Query: 154  ESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKM---DSAV 210
             S+L+ +  LL   +RL+ E    R++  ++   +++ RK    S  ++ E+    D   
Sbjct: 1047 LSQLESQNQLL--QERLQAEE---REKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKD 1101

Query: 211  QASLSLPA 218
            Q SL + A
Sbjct: 1102 QLSLRVKA 1109



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 39/180 (21%)

Query: 41  QEGSRELEAELEAQ----------LVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQS 90
           +EGS E E  +  +          LV     +    A    L  +VE L+ KL+ +  + 
Sbjct: 323 REGSSESETSVRRKVSLVLEKMQPLVMVSSGSTKAVAGQGELTRKVEELQRKLDEEVKKR 382

Query: 91  YK----QVSV---LEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRL 143
            K    QV +   LE+   +   ++E L +   E +Q+N +L+  KR            L
Sbjct: 383 QKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRL-----------L 431

Query: 144 NQAIERNAFLESELDEKESLLVSVQ--------RLKD--EARDLRQE-LAVRERQQEVTR 192
           +Q  +    LE+++ E ++ L  VQ         LKD  E R+L +E L  ++R +E  R
Sbjct: 432 DQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLR 491


>gi|157743265 caspase recruitment domain family, member 11 [Homo
           sapiens]
          Length = 1154

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 51/196 (26%), Positives = 101/196 (51%), Gaps = 14/196 (7%)

Query: 15  ETAYWKELSLKYKQSFQEARDELVEFQEGSRELE---AELEAQLVQAEQRNRDLQADNQR 71
           E   ++E   K K+      DELV+ ++ +  L    A+L  +   A  R+RDLQ +  +
Sbjct: 172 ELLTFQERYYKMKEERDSYNDELVKVKDDNYNLAMRYAQLSEEKNMAVMRSRDLQLEIDQ 231

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE---LEQANDDLERA 128
           LK+ +  ++E+ + +  QS K    L++D+ + R  KEQ+ +  RE   L+  N +L+  
Sbjct: 232 LKHRLNKMEEECKLERNQSLK----LKNDI-ENRPKKEQVLELERENEMLKTKNQELQSI 286

Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
            +A   SL D ++ +   +E +   +  L++++ L+  +  L++EAR   +EL  +  ++
Sbjct: 287 IQAGKRSLPDSDKAILDILEHDR--KEALEDRQELVNRIYNLQEEARQ-AEELRDKYLEE 343

Query: 189 EVTRKSAPSSPTLDCE 204
           +   +   S+   DCE
Sbjct: 344 KEDLELKCSTLGKDCE 359



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 9/124 (7%)

Query: 31  QEARDELVEFQEGSRELEAELEAQLVQAEQ---RNRDLQADNQRLKYEVEALK---EKLE 84
           QE  + +   QE +R+ E   +  L + E    +   L  D +  K+ +  +    E++E
Sbjct: 317 QELVNRIYNLQEEARQAEELRDKYLEEKEDLELKCSTLGKDCEMYKHRMNTVMLQLEEVE 376

Query: 85  HQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDD--LERAKR-ATIVSLEDFEQ 141
            +  Q++      +   SQ    K++  K +RELE+ ND+  +E  +R A IV+LE   +
Sbjct: 377 RERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELEEKNDEMRIEMVRREACIVNLESKLR 436

Query: 142 RLNQ 145
           RL++
Sbjct: 437 RLSK 440



 Score = 35.4 bits (80), Expect = 0.075
 Identities = 42/194 (21%), Positives = 81/194 (41%), Gaps = 23/194 (11%)

Query: 10  SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
           + ++EE    +  SLK K   +    +     E   ELE E E    + ++    +QA  
Sbjct: 237 NKMEEECKLERNQSLKLKNDIENRPKK-----EQVLELERENEMLKTKNQELQSIIQAGK 291

Query: 70  QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDL----SQTRAIKEQLHKYVRELEQ----- 120
           + L    +A+ + LEH   ++ +    L + +     + R  +E   KY+ E E      
Sbjct: 292 RSLPDSDKAILDILEHDRKEALEDRQELVNRIYNLQEEARQAEELRDKYLEEKEDLELKC 351

Query: 121 --ANDDLERAK---RATIVSLEDFEQRLNQAIERNAFLESE----LDEKESLLVSVQRLK 171
                D E  K      ++ LE+ E+  +QA       +++    L EK+     ++ L+
Sbjct: 352 STLGKDCEMYKHRMNTVMLQLEEVERERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELE 411

Query: 172 DEARDLRQELAVRE 185
           ++  ++R E+  RE
Sbjct: 412 EKNDEMRIEMVRRE 425


>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
          Length = 775

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 57/226 (25%), Positives = 107/226 (47%), Gaps = 36/226 (15%)

Query: 12  LKEETAYWKELSLKYKQSFQE------ARDELVEFQEGSRELEAELEA-----QLVQAEQ 60
           L+EE    ++L L+ +++ +       A +++  F+  +++L  E+E      Q ++ E+
Sbjct: 254 LQEERTQRQDLELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEK 313

Query: 61  RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQ----LHKYVR 116
              D +   Q L+ E   LK   + Q  Q  ++ ++ ED L Q   ++EQ    L   + 
Sbjct: 314 NQPDPRL--QELQEEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQIS 371

Query: 117 ELEQANDDLERAKRATIVSLEDFEQRL------NQAIERNAFLESELD---EKESLLVSV 167
           E+ +     E+AK+   ++++  ++R+      N+ +   A   S LD   E+ SL V+V
Sbjct: 372 EVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSHGEESSLDVNV 431

Query: 168 QRLKDEARDLRQELAVRERQQEVT--------RKSAPSSPTLDCEK 205
             LKD+   L++ L V  R+ +VT         +  PSS   D EK
Sbjct: 432 --LKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEK 475


>gi|169217489 PREDICTED: similar to phosphodiesterase 4D interacting
           protein [Homo sapiens]
          Length = 211

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 45/154 (29%), Positives = 81/154 (52%), Gaps = 14/154 (9%)

Query: 64  DLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDD---LSQTRAIKEQLHKYVRELEQ 120
           +L+   Q+L+ E++   ++L    A+ Y ++   E +   L+ + + KEQL +  REL Q
Sbjct: 3   ELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQ 62

Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQ- 179
             D+ ++   A  + LE   QR+    ++   LE  +DEK S       L+++ ++LRQ 
Sbjct: 63  YRDNSDKTLEANEMLLEKLRQRIR---DKAVALERAIDEKFS------ALEEKEKELRQL 113

Query: 180 ELAVRERQQEVTR-KSAPSSPTLDCEKMDSAVQA 212
            LAVRER  ++ R +   SS     + M+S ++A
Sbjct: 114 RLAVRERDHDLERLRDVLSSNEATMQTMESLLRA 147


>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
          Length = 976

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 52/192 (27%), Positives = 93/192 (48%), Gaps = 25/192 (13%)

Query: 14  EETAYWKELSLKYKQSFQEARD---ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
           E T++  +LSL+ K+  QE  D   EL   QE     + + E  L Q E    +LQ    
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE----NLQETET 570

Query: 71  RLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKR 130
           +L+ E+E ++E+L+ +  +   ++   E++ +  R   E  +KY+ EL+Q N  L++   
Sbjct: 571 QLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGT 630

Query: 131 ATIVSLEDFEQRLNQAI-----------ERNAFLESELDEK----ESLLVSVQRLK---D 172
           A    L  +E ++N+             E     + E+++K    E+LL  V++ K   D
Sbjct: 631 AESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIAD 690

Query: 173 EARDLRQELAVR 184
           EA  L++E+  R
Sbjct: 691 EAVKLQKEIDKR 702



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 10/172 (5%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           LKE  A   E + KY+   +E R   ++      ++    E   VQAE    ++    + 
Sbjct: 186 LKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKE 245

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
              +++ L+++ + +     KQVS+L   L Q    + ++      LE++ D + + +  
Sbjct: 246 DYEKIQHLEQEYKKEINDKEKQVSLL---LIQITEKENKMKDLTFLLEESRDKVNQLEEK 302

Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAV 183
           T +  E+    L Q+IE+   L  EL   E + VS+QR     + L ++L +
Sbjct: 303 TKLQSEN----LKQSIEKQHHLTKEL---EDIKVSLQRSVSTQKALEEDLQI 347



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 47/233 (20%), Positives = 101/233 (43%), Gaps = 27/233 (11%)

Query: 2   DGEDIPDFSSLKEETAYWKELSLKYKQSFQEA-RDELVEFQEGSRELEAELEAQLVQAEQ 60
           + E I  +    E     KE  L+  +   EA R  + E Q G+ ++  +LE  +    Q
Sbjct: 112 EAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGI----Q 167

Query: 61  RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
            N+DL  +N   ++    LKE      A+S ++    E +  +TR +   L+  + ++  
Sbjct: 168 ENKDLIKENNATRHLCNLLKETC----ARSAEKTKKYEYEREETRQVYMDLNNNIEKMIT 223

Query: 121 ANDDLERAKRATIVSL---------------EDFEQRLNQAIERNAFLESELDEKESLLV 165
           A ++L      + + +               +++++ +N   ++ + L  ++ EKE+ + 
Sbjct: 224 AFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMK 283

Query: 166 SVQRLKDEARDLRQELAVRERQQEVTRKSAPSSP---TLDCEKMDSAVQASLS 215
            +  L +E+RD   +L  + + Q    K +       T + E +  ++Q S+S
Sbjct: 284 DLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVS 336



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 43/207 (20%), Positives = 90/207 (43%), Gaps = 42/207 (20%)

Query: 21  ELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQA---EQRNRDL-----------Q 66
           E+  K K+ +++ +    E+++   + E ++   L+Q    E + +DL            
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVN 297

Query: 67  ADNQRLKYEVEALKEKLE--HQYAQSYKQVSV-LEDDLSQTRAIKEQLHKYVREL----E 119
              ++ K + E LK+ +E  H   +  + + V L+  +S  +A++E L    + +    E
Sbjct: 298 QLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTE 357

Query: 120 QANDDLERAKRA-------------TIVSLEDFEQRLNQAIERN----AFLESELDEKES 162
           +    +E + +A             T+ SLE+  +   Q +E+N      L  EL +K S
Sbjct: 358 EKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSS 417

Query: 163 LLVSVQRLKD----EARDLRQELAVRE 185
            L  + +L +    E  +L++ L  +E
Sbjct: 418 ELEEMTKLTNNKEVELEELKKVLGEKE 444


>gi|32698688 citron [Homo sapiens]
          Length = 2027

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 45/167 (26%), Positives = 81/167 (48%), Gaps = 23/167 (13%)

Query: 34   RDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEAL---KEKLEHQYAQS 90
            ++ L+E +   RE+  E E Q ++ +++  +LQ   Q  + ++ AL   +  LE Q  Q+
Sbjct: 848  KNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQA 907

Query: 91   YKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER---AKRATIVSLEDFEQRLNQAI 147
                   + +L +T A  E+    ++ L    D+++R   A R +   + D E++LNQ  
Sbjct: 908  -------KTELEETTAEAEE---EIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLT 957

Query: 148  ERNA-------FLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
            E NA       +L  +LDE       + +L+ E   LR+E+  RE Q
Sbjct: 958  EDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQ 1004



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 34/127 (26%), Positives = 57/127 (44%), Gaps = 13/127 (10%)

Query: 75  EVEALKEKLEHQYAQSYKQVSVLEDDL----SQTRAIKEQLHKYVRELEQANDD----LE 126
           EVEA+  + E +   S  Q S+LE DL    ++  ++K  L +   E+ Q +D     L 
Sbjct: 481 EVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLH 540

Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKD--EARDLRQELAVR 184
             +  +    E  EQ     +E    + ++L+E    LVS +R  D  E+      LA  
Sbjct: 541 DIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEED---LVSARRRSDLYESELRESRLAAE 597

Query: 185 ERQQEVT 191
           E +++ T
Sbjct: 598 EFKRKAT 604


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 7/193 (3%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           L+ E    +E  LK ++  +  +  L   Q+  RE E   E  L + E++  + +   QR
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566

Query: 72  LKYEVEALKEKL-EHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYV----RELEQANDDLE 126
           LK E E  +++L + +  +  +++   +++  + R  +E++ +      RE     ++ E
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626

Query: 127 RAKRATIVSLEDFEQRLNQAI--ERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVR 184
             +R  ++  E+ E+R  Q +  E+    E  L  +E      QRLK E  + R+E  + 
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686

Query: 185 ERQQEVTRKSAPS 197
           E +QE  R+   S
Sbjct: 687 EEEQEQARERIKS 699



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 51/192 (26%), Positives = 83/192 (43%), Gaps = 21/192 (10%)

Query: 4   EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVE--FQEGSRELEAELEAQLVQAEQR 61
           E+ PD   L+       EL  K ++  Q+ R E  +  FQE   +   + E  L + E++
Sbjct: 202 EEFPDEEQLRRRELL--ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259

Query: 62  NRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQA 121
            ++ +   QR   E E    KLE Q  +  +Q    E++  Q R  +EQ  +  +E E+ 
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQ----EEEQQQQRLRREQQLRRKQEEERR 315

Query: 122 NDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
               ER         E  E+R  Q   R   L  E +E+       Q+L+ E  + R+E 
Sbjct: 316 EQQEERR--------EQQERREQQEERREQQLRREQEERRE-----QQLRREQEEERREQ 362

Query: 182 AVRERQQEVTRK 193
            +R  Q+E  R+
Sbjct: 363 QLRREQEEERRE 374



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 50/178 (28%), Positives = 81/178 (45%), Gaps = 9/178 (5%)

Query: 13  KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA-ELEAQLVQAEQRNRDLQADNQR 71
           K ET   KE     ++  Q  R EL E +E  R+LE  EL  +  + EQ+ + L+ + Q 
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQR-ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            + + E  +E+ E +  Q  ++    E    Q R  +E+     R  +Q   + E  +R 
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEE-----RREQQLRREQEEERRE 361

Query: 132 TIVSLEDFEQRLNQAIERNAFLESELD-EKESLLVSVQRLKDEARDLRQELAVRERQQ 188
             +  E  E+R  Q + R   L  E    +E  L   Q+L+ E + LR+E  +R  QQ
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQQLRREQQ 418



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 16/177 (9%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           L+ E    +E  L+ +Q  +  + +L   Q+  RE +   E QL + +Q  R+ + +   
Sbjct: 377 LRREQQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
            K+E E  +++L+ +  +    +          R  + + H+  R  +Q   D E  +R 
Sbjct: 436 QKHEQERREQRLKREQEERRDWLK---------REEETERHEQERRKQQLKRDQEEERRE 486

Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
             + LE+ E+R  Q   R   L  E +E+       QRLK +  + R +  +R  QQ
Sbjct: 487 RWLKLEE-EERREQQERREQQLRREQEERRE-----QRLKRQEEEERLQQRLRSEQQ 537



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 42/185 (22%), Positives = 89/185 (48%), Gaps = 18/185 (9%)

Query: 20   KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR----DLQADNQRLK-- 73
            KEL    ++   + R+   + QE    L+ + E +  Q ++R++     L+ + +R +  
Sbjct: 829  KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888

Query: 74   -YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
             Y   AL+E+L  +     ++   L+ +  + R  +EQ  +Y RE EQ   + E+  R  
Sbjct: 889  LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY-REEEQLQQEEEQLLR-- 945

Query: 133  IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ----RLKDEARDLRQELAVRERQQ 188
                E+ E+R  Q  ER    + +L +KE  L+  +    R ++  +  R+E  +++ ++
Sbjct: 946  ----EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001

Query: 189  EVTRK 193
            ++ R+
Sbjct: 1002 QLLRE 1006



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 48/205 (23%), Positives = 92/205 (44%), Gaps = 34/205 (16%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA----- 67
            +EE    +E  L  ++  +  R E         EL+ E E QL++ E+  R LQ      
Sbjct: 992  EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE-EEQLLREEREKRRLQERERQY 1050

Query: 68   -DNQRLKYEVEAL---------KEKLEHQYA-----QSYKQVSVLEDDLSQTRAIKEQLH 112
             + + L+ E E L         +++LE QY      Q  ++  + E+   + R  +E+  
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110

Query: 113  KYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLV----SVQ 168
            +   EL+Q  + L R +R         E+R  Q +ER    E E+ ++E  L+      +
Sbjct: 1111 REEEELQQEEEQLLREER---------EKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161

Query: 169  RLKDEARDLRQELAVRERQQEVTRK 193
            R ++  R  R+E  +++ ++++ R+
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLRE 1186



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 45/186 (24%), Positives = 86/186 (46%), Gaps = 14/186 (7%)

Query: 13   KEETAYWKELSLKYK---QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
            +E+    +EL  K++   Q  QE   E +  QE  R++   LE + ++ E+  + L+   
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI---LEEEQLRPEREEQQLRRQE 1768

Query: 70   QRLKY-EVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
            +  K+ E E L+++ E Q  +S +      ++  Q R  +E+     ++L     D +  
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREE-EQLRQEREE-----QQLRPQQRDGKYR 1822

Query: 129  KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRL-KDEARDLRQELAVRERQ 187
                 + LE+ EQRL Q  +R    E +   +E      Q L ++E +  RQE   + R+
Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882

Query: 188  QEVTRK 193
            + + R+
Sbjct: 1883 EHIRRQ 1888



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 35/180 (19%), Positives = 75/180 (41%), Gaps = 7/180 (3%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           L+ E    +E  L+ +Q  +    +L   QE  R      E QL + +Q  R+ Q   ++
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERR-----EQQLRREQQLRREQQLRREQ 393

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK-- 129
                + L+ + + +  Q  ++   L  +    R  +E+ H+   E E+    L+R +  
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE 453

Query: 130 RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
           R   +  E+  +R  Q   +      + +E+    + ++  +   +  R+E  +R  Q+E
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 55/200 (27%), Positives = 91/200 (45%), Gaps = 24/200 (12%)

Query: 4   EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE-LEAQLVQAEQRN 62
           E+  D+   +EET    E   + ++  Q  RD+  E +E   +LE E    Q  + EQ+ 
Sbjct: 452 EERRDWLKREEET----ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507

Query: 63  RDLQAD--NQRLK--YEVEALKEKLEHQY----AQSYKQVSVLEDDLSQTRAIKEQLHKY 114
           R  Q +   QRLK   E E L+++L  +      Q  ++  +L+ +  +    + +  + 
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567

Query: 115 VRELEQANDDL---ERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLK 171
            RE E+  D L   E  +R   +  E  E+RL Q ++R      E +E+       QRLK
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQ-EERLEQRLKREEVERLEQEERRE-----QRLK 621

Query: 172 DE--ARDLRQELAVRERQQE 189
            E    + RQ+L   E Q+E
Sbjct: 622 REEPEEERRQQLLKSEEQEE 641



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 49/203 (24%), Positives = 90/203 (44%), Gaps = 15/203 (7%)

Query: 13   KEETAYWKELSLKYK---QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
            +EE    +E   K++   Q  QE  ++ +  QE  R+   E   +L   EQ  + L+ + 
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE---ELRHQEQGRKFLEEEQ 1381

Query: 70   QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK 129
            +  + E E    K E Q     ++  + +D   + R  ++QL +  R+ +   ++ +  +
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441

Query: 130  RATIVSLEDFEQRLNQAIERNAFLESE--LDEKESLLVSVQR-----LKDEARDLRQELA 182
            +       + EQ+L Q   R  F E E  L E+E   +  Q      L++E +  RQE  
Sbjct: 1442 QERERKFLEEEQQLRQERHRK-FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500

Query: 183  VRERQQEVTRKSAPSSPTLDCEK 205
             + R+QE+ R   P    L+ E+
Sbjct: 1501 RKFREQEL-RSQEPERKFLEEEQ 1522



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 43/193 (22%), Positives = 82/193 (42%), Gaps = 31/193 (16%)

Query: 27   KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEV---------- 76
            +Q  QE  ++ +  QE  R+    LE Q V+ +++ R    D Q+L+ +           
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFR--LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618

Query: 77   -------EALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVR--------ELEQA 121
                   + L+E+ E Q  +  +    LE++    R  +EQ  ++ R        +L Q 
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678

Query: 122  NDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
             ++ +  ++       + EQ+L +      FL+   +E++     ++R   E   LRQE 
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQ---EEQQLRRQELERKFREEEQLRQET 1735

Query: 182  AVRE-RQQEVTRK 193
               + R+QE  RK
Sbjct: 1736 EQEQLRRQERYRK 1748



 Score = 35.4 bits (80), Expect = 0.075
 Identities = 48/195 (24%), Positives = 79/195 (40%), Gaps = 35/195 (17%)

Query: 28   QSFQEARDELVEFQEGSRELEAELEA----QLVQAEQRNR-----------DLQADNQRL 72
            Q  QE  D L E QE  R  E   +     QL +  +R R            L+ + Q L
Sbjct: 847  QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906

Query: 73   KYEVEAL------KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
            + E E L      K + + Q  Q  ++  + +++    R  +E+  +  RE +   D   
Sbjct: 907  QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELD-EKESLLVSVQ------------RLKDE 173
            + K   ++  E+ E+R  Q  E+    E EL  E+E LL   +            R KDE
Sbjct: 967  QQKEEQLLG-EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025

Query: 174  ARDLRQELAVRERQQ 188
             +   ++L   ER++
Sbjct: 1026 LQQEEEQLLREEREK 1040



 Score = 35.4 bits (80), Expect = 0.075
 Identities = 45/209 (21%), Positives = 85/209 (40%), Gaps = 41/209 (19%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR--------- 63
            +EE    +E  L  ++  +  R EL        EL+ E E QL++ EQ  R         
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE-EEQLLREEQEKRRQERERQYR 1200

Query: 64   ---DLQADNQRLKYEVEALKEKLEHQY----------------AQSYKQVSVLEDDLSQT 104
               +LQ   ++ +Y  E  +  L+ Q+                 +  +Q   LED   + 
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260

Query: 105  RAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
            R  ++ L   + E ++ + + ER +         ++QR     E     + E +E++   
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRR---------WQQRDRHFPEEE---QLEREEQKEAK 1308

Query: 165  VSVQRLKDEARDLRQELAVRERQQEVTRK 193
               ++ ++E + LR+E   + R+QE  RK
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRK 1337



 Score = 35.0 bits (79), Expect = 0.098
 Identities = 40/169 (23%), Positives = 81/169 (47%), Gaps = 14/169 (8%)

Query: 27   KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQ 86
            +Q  ++ RD   +F+E  + L+   E QL + E+  + L+ + Q  + E E   ++L H 
Sbjct: 1610 QQQLRQERDR--KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE---QQLRHD 1664

Query: 87   YAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE--LEQANDDLERAKRATIVSLEDFEQRLN 144
              + +++    E+ L Q    ++QL +  R+    +    L R +R     L++ +Q   
Sbjct: 1665 RDRKFRE----EEQLLQ-EGEEQQLRRQERDRKFREEEQQLRRQERER-KFLQEEQQLRR 1718

Query: 145  QAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
            Q +ER  F E E   +E+    ++R +   + L +E    ER+++  R+
Sbjct: 1719 QELERK-FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 41/177 (23%), Positives = 81/177 (45%), Gaps = 14/177 (7%)

Query: 27   KQSFQEARDELVEFQEGSREL-EAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEH 85
            +Q  ++ RD   +F+E  ++L   E E + +Q EQ+ R  + + ++ + E +  +E  + 
Sbjct: 1682 QQLRRQERDR--KFREEEQQLRRQERERKFLQEEQQLRRQELE-RKFREEEQLRQETEQE 1738

Query: 86   QYAQSYKQVSVLEDDLSQTRAIKEQLHKY-----VRELEQANDDLERAKRATIVSLEDF- 139
            Q  +  +   +LE++  +    ++QL +       RE EQ   + E  +  +  S   F 
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798

Query: 140  -EQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSA 195
             E++L Q  E       + D K        +L+++ + LRQE   R+RQ     + A
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE---RDRQYRAEEQFA 1852



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 38/191 (19%), Positives = 86/191 (45%), Gaps = 20/191 (10%)

Query: 20   KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVE-- 77
            +EL  + +Q  +E +++  + +E     E EL+ Q  +   R+ D ++D   LK++ E  
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD---LKWQWEPE 1230

Query: 78   ---ALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK----- 129
               A+++   +   +  +Q   LED   + R  ++ L   + E ++ + + ER +     
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290

Query: 130  -------RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELA 182
                   +      ++ ++R  ++ E    L  E +EK     + ++ ++E + L++   
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350

Query: 183  VRERQQEVTRK 193
               R+QE  RK
Sbjct: 1351 QPLRRQERDRK 1361



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 45/189 (23%), Positives = 83/189 (43%), Gaps = 18/189 (9%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
            KEE    +E  L  ++  +  R E         EL+ E E QL++ E+  R  Q   ++ 
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE-EEQLLREEREKRRRQELERQY 1140

Query: 73   KYEVEA-------LKEKLEHQYAQSYKQVSVLEDDLSQ--TRAIKEQLHKYVRELE---Q 120
            + E E        L+E+ E +  Q  ++    E++L Q   + ++E+  K  +E E   +
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200

Query: 121  ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
              ++L+R KR      ED    L    E     E E   +++ +    R  ++ R L ++
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEP----EKENAVRDNKVYCKGRENEQFRQL-ED 1255

Query: 181  LAVRERQQE 189
              +R+RQ +
Sbjct: 1256 SQLRDRQSQ 1264


>gi|119120918 coiled-coil domain containing 64 [Homo sapiens]
          Length = 573

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 43/174 (24%), Positives = 84/174 (48%), Gaps = 23/174 (13%)

Query: 20  KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEAL 79
           +++S +Y+Q  +E  D+L   ++   EL    E +  + E R  +L++D       V+ L
Sbjct: 125 QDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELESD-------VKQL 177

Query: 80  KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQAN--DDLERAKRATIVSL- 136
           +++LE Q      Q+ + E D  ++RA++E   +  R L+Q +   ++ER     + +L 
Sbjct: 178 QDELERQ------QIHLREADREKSRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALR 231

Query: 137 EDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEV 190
           EDF        E+N+     +   ESL   ++ L D  R+L   L+    + ++
Sbjct: 232 EDFR-------EKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDL 278



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 45/208 (21%), Positives = 90/208 (43%), Gaps = 20/208 (9%)

Query: 21  ELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRD-------LQADNQRLK 73
           EL  +++    E    + E +   ++L+ ELE Q +   + +R+       L   NQRL 
Sbjct: 151 ELRRRFENREGEWEGRVSELESDVKQLQDELERQQIHLREADREKSRAVQELSEQNQRLL 210

Query: 74  YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQ-------LHKYVRELEQANDDLE 126
            ++    E +E Q +    QV  L +D  +  +   Q       L   ++ L     +LE
Sbjct: 211 DQLSRASE-VERQLSM---QVHALREDFREKNSSTNQHIIRLESLQAEIKMLSDRKRELE 266

Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEAR-DLRQ-ELAVR 184
               AT+   +  +  + +  +R   LE +  +K+  L   Q    E R   RQ ++ V 
Sbjct: 267 HRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLELQEVRLSCRQLQVKVE 326

Query: 185 ERQQEVTRKSAPSSPTLDCEKMDSAVQA 212
           E  +E + +S+ ++ T    +++ +++A
Sbjct: 327 ELTEERSLQSSAATSTSLLSEIEQSMEA 354


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 40/160 (25%), Positives = 85/160 (53%), Gaps = 6/160 (3%)

Query: 31   QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQS 90
            +E R  L   ++   E+  +LEA++ + E+R + LQA+ ++++  ++ L+E+LE +  +S
Sbjct: 900  EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEE--ES 957

Query: 91   YKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERN 150
             +Q   LE   ++ +  K +  + +  LE  N  L + K+     + +F   L +  E++
Sbjct: 958  ARQKLQLEKVTTEAKLKKLEEEQII--LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015

Query: 151  AFLESELDEKESLLVSV-QRLKDEARDLRQELAVRERQQE 189
              L    ++ E+++  + +RL+ E +  RQEL    R+ E
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQ-RQELEKTRRKLE 1054



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 43/170 (25%), Positives = 79/170 (46%), Gaps = 14/170 (8%)

Query: 27   KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ--RNRDLQADNQR--LKYEVEALKEK 82
            K   +E  DEL   ++    LE  L+A   Q E+  + RD Q++ ++  L  +V  ++ +
Sbjct: 1538 KTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE 1597

Query: 83   LEHQYAQSYKQVSV---LEDDLSQTRAI-------KEQLHKYVRELEQANDDLERAKRAT 132
            LE +  Q    V+    LE DL    A        +++  K +R+L+    D  R    T
Sbjct: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657

Query: 133  IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELA 182
              S E+   +  +  ++   +E+E+ + +  L + +R K +A+  R ELA
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELA 1707



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 47/206 (22%), Positives = 94/206 (45%), Gaps = 11/206 (5%)

Query: 25   KYKQSFQEARDEL----VEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALK 80
            K +Q  ++ R +L     +  +   EL+A++    +Q  ++  +LQA   R++ E  A K
Sbjct: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA-AQK 1099

Query: 81   EKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVS-LEDF 139
                 +  +   Q+S L++DL   RA + +  K  R+L +  + L+     T+ S     
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159

Query: 140  EQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVR-ERQQEVTRKSAPSS 198
            E R  +  E N   ++  +E ++    +Q ++ +     +ELA + E+ + V      + 
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219

Query: 199  PTLDCEKMDSAVQASLSLPATPVGKG 224
             TL+ E+ + A +  + L     GKG
Sbjct: 1220 QTLENERGELANEVKVLLQ----GKG 1241



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 44/204 (21%), Positives = 90/204 (44%), Gaps = 17/204 (8%)

Query: 11   SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
            +L+EE    +    + +Q   +A +EL E  E ++ ++A LE       +  + L+ +  
Sbjct: 1175 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE-------KAKQTLENERG 1227

Query: 71   RLKYEVEAL---KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDD--- 124
             L  EV+ L   K   EH+  +   Q+  L+   ++   ++ +L   V +L+   D+   
Sbjct: 1228 ELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTG 1287

Query: 125  -LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAV 183
             L ++   +    +DF    +Q  +    L+ E  +K SL   +++++DE    R++L  
Sbjct: 1288 LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQL-- 1345

Query: 184  RERQQEVTRKSAPSSPTLDCEKMD 207
             E ++E          TL  +  D
Sbjct: 1346 -EEEEEAKHNLEKQIATLHAQVAD 1368



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 40/164 (24%), Positives = 73/164 (44%), Gaps = 15/164 (9%)

Query: 49   AELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIK 108
            AE    L + E++++ L     +LK + EA+   LE +  +  KQ   LE    +     
Sbjct: 1002 AEFTTNLTEEEEKSKSLA----KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDS 1057

Query: 109  EQLHKYVRELEQANDDL-------ERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKE 161
              L   + EL+    +L       E   +A +  +E+   + N A+++   LES++ E +
Sbjct: 1058 TDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQ 1117

Query: 162  SLLVSVQRLKDEA----RDLRQELAVRERQQEVTRKSAPSSPTL 201
              L S +  +++A    RDL +EL   + + E T  S  +   L
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQEL 1161



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/181 (26%), Positives = 86/181 (47%), Gaps = 27/181 (14%)

Query: 27   KQSFQEARDELVEFQEGSRELEAE---LEAQLVQAEQRNRDLQADNQRLKYEVE------ 77
            + S +E   +  E ++  + +EAE   L+ +L  AE+  R  Q +   L  E+       
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717

Query: 78   --ALKEK--LEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
              AL+EK  LE + AQ  ++   LE++   T  I ++L K   +++Q N DL   +R+  
Sbjct: 1718 ALALEEKRRLEARIAQLEEE---LEEEQGNTELINDRLKKANLQIDQINTDL-NLERSHA 1773

Query: 134  VSLEDFEQRLNQAIERNAFLESELDEKESLL-----VSVQRLKDEARDLRQEL--AVRER 186
               E+  Q+L +   +N  L+ +L E E  +      S+  L+ +   L ++L    +ER
Sbjct: 1774 QKNENARQQLER---QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKER 1830

Query: 187  Q 187
            Q
Sbjct: 1831 Q 1831



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 53/233 (22%), Positives = 97/233 (41%), Gaps = 31/233 (13%)

Query: 4    EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQ-----A 58
            +D+   S   EE     +   K K   Q+  D+L+   +  R+    LE +  +     A
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 1451

Query: 59   EQRNRDLQADNQRLKYEVEALKEK-----LEHQYAQSYKQVSVLE-------DDLSQTRA 106
            E++    +   +R + E EA +++     L     ++ +Q + LE        ++    +
Sbjct: 1452 EEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS 1511

Query: 107  IKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVS 166
             K+ + K V ELE++   LE+        LE+ E  L QA E         D K  L V+
Sbjct: 1512 SKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDEL-QATE---------DAKLRLEVN 1561

Query: 167  VQRLKDEARDLRQELAVRERQQEVTRKS-APSSPTLDCEKMDSAVQASLSLPA 218
            +Q +K +     ++L  R+ Q E  +K        ++ E  D   Q S+++ A
Sbjct: 1562 LQAMKAQ---FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAA 1611



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 46/183 (25%), Positives = 86/183 (46%), Gaps = 23/183 (12%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           LK     W  L  K K   Q +R E         E+ A+ E +LV+   R + L A+N+ 
Sbjct: 820 LKLRNWQWWRLFTKVKPLLQVSRQE--------EEMMAK-EEELVKV--REKQLAAENRL 868

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE---RA 128
              E+E L+ +L  +  Q  +Q+    +  ++   ++ +L    +ELE+   DLE     
Sbjct: 869 T--EMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEE 926

Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESL--LVSVQRLKDEA--RDLRQELAVR 184
           +      L+  ++++ Q I+    LE +L+E+ES    + ++++  EA  + L +E  + 
Sbjct: 927 EEERCQHLQAEKKKMQQNIQE---LEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983

Query: 185 ERQ 187
           E Q
Sbjct: 984 EDQ 986



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 38/183 (20%), Positives = 82/183 (44%), Gaps = 22/183 (12%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELE---AQLVQAEQRNRDLQADN 69
            K+  A  +EL +K+ +  +  R EL +      +L+ EL+     L Q++ ++  L  D 
Sbjct: 1248 KKVEAQLQELQVKFNEG-ERVRTELAD---KVTKLQVELDNVTGLLSQSDSKSSKLTKDF 1303

Query: 70   QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK 129
              L+ +++  +E L+ +  Q     + L+    +  + +EQL     E E+A  +LE+  
Sbjct: 1304 SALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE----EEEEAKHNLEKQI 1359

Query: 130  RATIVSLEDFEQRLNQAI-------ERNAFLESELD----EKESLLVSVQRLKDEARDLR 178
                  + D ++++  ++       E    L+ +L+      E  + +  +L+     L+
Sbjct: 1360 ATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQ 1419

Query: 179  QEL 181
            QEL
Sbjct: 1420 QEL 1422



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 21/150 (14%)

Query: 20   KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEAL 79
            KEL +K ++     + +   ++     LEA++     Q +   ++ QA  ++++   + L
Sbjct: 1788 KELKVKLQEMEGTVKSK---YKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL 1844

Query: 80   KEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIV 134
            K+ L     E + A+ YK     + D + TR     L +  R+LE+A ++ +RA      
Sbjct: 1845 KDVLLQVDDERRNAEQYKD----QADKASTR-----LKQLKRQLEEAEEEAQRAN----A 1891

Query: 135  SLEDFEQRLNQAIERNAFLESELDEKESLL 164
            S    ++ L  A E    +  E+   ++ L
Sbjct: 1892 SRRKLQRELEDATETADAMNREVSSLKNKL 1921


>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
          Length = 1417

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 41/189 (21%), Positives = 94/189 (49%), Gaps = 10/189 (5%)

Query: 20  KELSLKYKQSFQEARDE-------LVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
           +++ ++ +QS QE+++E       L+E  +  +  E +    L  AE+ ++  Q   +++
Sbjct: 318 QKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKV 377

Query: 73  KYEVE---ALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK 129
             ++E   A +E LE       K+   L++     ++  E L + +R+L++ N++ +   
Sbjct: 378 AEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKL 437

Query: 130 RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
           R   V   +   +L ++ +    LESEL+ K+ +L     L +E R+L+  +A +  + +
Sbjct: 438 RIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLD 497

Query: 190 VTRKSAPSS 198
           + ++   SS
Sbjct: 498 LCQQEIESS 506



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 46/189 (24%), Positives = 89/189 (47%), Gaps = 25/189 (13%)

Query: 15   ETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR---DLQADNQR 71
            +T   K++S K +Q  Q+ R+   E     R++E + E+   +A+ + +   +L    ++
Sbjct: 932  QTKLEKQVS-KLEQELQKQRESSAE---KLRKMEEKCESAAHEADLKRQKVIELTGTARQ 987

Query: 72   LKYEVEALKEKLEHQYAQSYKQVSVLEDD-------LSQTRAIKEQLHKYVRELEQANDD 124
            +K E++  KE+L    ++  K++  L+ D       LSQ   I +Q    + +   A  +
Sbjct: 988  VKIEMDQYKEEL----SKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKE 1043

Query: 125  LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVR 184
            LE+ + +T       E  L +A+++   LE+EL      L S  R   E RD+ Q+  + 
Sbjct: 1044 LEKLQHST-------ETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLS 1096

Query: 185  ERQQEVTRK 193
              ++  T K
Sbjct: 1097 LEEKYTTIK 1105



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 45/175 (25%), Positives = 78/175 (44%), Gaps = 17/175 (9%)

Query: 14   EETAYWKELSLKY-KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
            E T    EL LK   +  +   D+L   +E  RE E  +     +  Q  ++++   QR+
Sbjct: 1168 EGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRM 1227

Query: 73   KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTR--------AIKEQLHKYV---RELEQA 121
            K E+E++ ++ E   A  YK+   L  +L  TR         + E  H+ V   RE+E+ 
Sbjct: 1228 K-EMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERL 1286

Query: 122  NDDLERAKRAT---IVSLEDFEQRLNQAIERNAFLESELD-EKESLLVSVQRLKD 172
            + +LE  K+ +           + L  +  R A LE+ +  E + L   V+ LK+
Sbjct: 1287 SSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKE 1341



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 30/142 (21%), Positives = 64/142 (45%), Gaps = 7/142 (4%)

Query: 45   RELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVL---EDDL 101
            RE   E+E ++++ E      + + +    ++E+L +KL++   Q  ++  ++   E ++
Sbjct: 1154 REHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEI 1213

Query: 102  SQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKE 161
            SQ +   E+  + ++E+E    + E+          D  Q L    E+     +EL E  
Sbjct: 1214 SQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEAR 1273

Query: 162  SLLV----SVQRLKDEARDLRQ 179
               V     ++RL  E  D++Q
Sbjct: 1274 HQQVQAQREIERLSSELEDMKQ 1295



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 33/202 (16%)

Query: 31   QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEK-------- 82
            Q+A+  L E     ++L AEL    ++ E + ++L   +Q LK     LK++        
Sbjct: 1091 QKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLD 1150

Query: 83   --LEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK----RATIVSL 136
              +     +  +++  LE  L ++     +L +  +++E  ND L+ AK        + L
Sbjct: 1151 MTIREHRGEMEQKIIKLEGTLEKSEL---ELKECNKQIESLNDKLQNAKEQLREKEFIML 1207

Query: 137  EDFEQ--RLNQAIERN----AFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEV 190
            ++ ++  +L + IER       +ES + E+E  + +  +   EA DL QEL        +
Sbjct: 1208 QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYK---EAIDLGQEL-------RL 1257

Query: 191  TRKSAPSSPTLDCEKMDSAVQA 212
            TR+   +S T   E     VQA
Sbjct: 1258 TREQVQNSHTELAEARHQQVQA 1279



 Score = 36.2 bits (82), Expect = 0.044
 Identities = 30/152 (19%), Positives = 70/152 (46%), Gaps = 8/152 (5%)

Query: 50  ELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKE 109
           EL  +L+Q E  N DL+ +      + + ++E+L  + + S K  S +    SQ   +++
Sbjct: 645 ELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEK 704

Query: 110 QLHKYV---RELEQANDDLERAKRATIVSLEDFEQRLNQAIER--NAFLESE---LDEKE 161
           QL + +     +   N +LE+        +   E  +N   E+   AF +++   L++ +
Sbjct: 705 QLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHK 764

Query: 162 SLLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
            +   ++RL+ +     Q+   +E+   + ++
Sbjct: 765 EMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQ 796



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 10/177 (5%)

Query: 27  KQSFQEARDELVEFQEGSRELEAELEA-QLVQAEQRNRDLQADNQRLKYEVEALKEKLEH 85
           K    E R +L   +   ++L A L A QL Q+     D Q  ++    E E +K    H
Sbjct: 556 KLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLG-GH 614

Query: 86  QYAQSYKQVSV------LEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDF 139
           Q A+S K  +        E +  +     E+L   + ++E  N DL+          +  
Sbjct: 615 QVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLI 674

Query: 140 EQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVR--ERQQEVTRKS 194
           ++ L +    ++ LESE+ +K S L+++++  +E       +A +  E +QE+  K+
Sbjct: 675 QEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKN 731



 Score = 32.7 bits (73), Expect = 0.49
 Identities = 38/189 (20%), Positives = 82/189 (43%), Gaps = 15/189 (7%)

Query: 10   SSLKEETAYWKELSLKYKQSF---QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQ 66
            S +KE+  Y   ++ +YK++    QE R    + Q    EL AE   Q VQA       Q
Sbjct: 1232 SVMKEQEQY---IATQYKEAIDLGQELRLTREQVQNSHTEL-AEARHQQVQA-------Q 1280

Query: 67   ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
             + +RL  E+E +K+  + + A        L     +   ++ ++   +++L    + L+
Sbjct: 1281 REIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLK 1340

Query: 127  RAKRATIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRE 185
             A    ++S ++   +   + +       +L+E+ E   + ++  +D   +L Q++  R 
Sbjct: 1341 EAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRN 1400

Query: 186  RQQEVTRKS 194
               E   ++
Sbjct: 1401 EVIEAANEA 1409



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 35/188 (18%), Positives = 76/188 (40%), Gaps = 20/188 (10%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELE-------AQLVQAEQRNRDL 65
            KE+    + + L+ +Q   + + E+   Q+  +E+E+ ++        Q  +A    ++L
Sbjct: 1196 KEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQEL 1255

Query: 66   QADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ----- 120
            +   ++++     L E   HQ  Q+ +++  L  +L   + + ++   +   L +     
Sbjct: 1256 RLTREQVQNSHTELAE-ARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGAS 1314

Query: 121  --ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEK-----ESLLVSVQRLKDE 173
                  LE   +A I  L    + L +A         E   K     +S   SVQ+L ++
Sbjct: 1315 KVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQ 1374

Query: 174  ARDLRQEL 181
                + EL
Sbjct: 1375 LEKAKLEL 1382



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 29/162 (17%), Positives = 67/162 (41%), Gaps = 8/162 (4%)

Query: 32   EARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYA 88
            + + EL +     +ELE      E +L +A Q+   L+ + Q    E+++   +L+    
Sbjct: 1029 QTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRD 1088

Query: 89   QSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIE 148
               K    LE+  +  + +  +L +   E+E    +L    +A      + +QR  Q   
Sbjct: 1089 VLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTH 1148

Query: 149  RNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEV 190
             +  +     E E  ++ ++   +     + EL ++E  +++
Sbjct: 1149 LDMTIREHRGEMEQKIIKLEGTLE-----KSELELKECNKQI 1185



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 31/149 (20%), Positives = 66/149 (44%), Gaps = 11/149 (7%)

Query: 49  AELEAQLVQAEQRNRDLQA----DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQT 104
           AELE +L++  ++ R L+     +++++    E  K+    Q+ +  KQ+  LE  L + 
Sbjct: 721 AELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKK 780

Query: 105 RAIKEQLHKYVRELEQ----ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEK 160
               ++  K +  L+Q        LE   R    S  + ++   +  E    L++++ E+
Sbjct: 781 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEE 840

Query: 161 ESLLVSVQRLKDEARDLRQELAVRERQQE 189
               + V++L       ++EL +   Q E
Sbjct: 841 ---TIKVRQLDSALEICKEELVLHLNQLE 866


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 60/285 (21%), Positives = 109/285 (38%), Gaps = 27/285 (9%)

Query: 13  KEETAYWKELSLK-YKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           K+E     E  LK YK+ +     +  E +   ++LEA+        EQ  +DLQ   Q 
Sbjct: 700 KQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQ- 758

Query: 72  LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQ----TRAIKEQLHKYVRELEQANDDLER 127
           L  ++E    +L  Q     + VS    DL +      +IK++L K   E +    D E 
Sbjct: 759 LNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFET 818

Query: 128 AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
             + T +  E+   R+   +     L+    EKE+L+  +  +KD+   +   L   + +
Sbjct: 819 LSQETKIQHEELNNRIQTTVTE---LQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSE 875

Query: 188 QEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFGTSPLTPS 247
            E   +   ++  LD EK    ++  L +         ENT    K +            
Sbjct: 876 FEKENQKGKAA-ILDLEKTCKELKHQLQVQ-------MENTLKEQKELKKSLEKEK---- 923

Query: 248 ARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVN 292
                      L  ++ +++ +L   +N  K     +  + GN+N
Sbjct: 924 ------EASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNIN 962



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 50/224 (22%), Positives = 94/224 (41%), Gaps = 32/224 (14%)

Query: 8    DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA 67
            + + L EE    K  S+K   + ++A+  L++ +    EL+ + ++     EQ  R+ Q 
Sbjct: 1139 EITKLNEELKSHKLESIKEITNLKDAKQLLIQQK---LELQGKADSLKAAVEQEKRNQQI 1195

Query: 68   DNQRLKYEVEALKE---------------------KLEHQYAQSYKQVSVLEDDLSQTRA 106
               ++K E E LK+                     K E   A+   Q++ L ++L   + 
Sbjct: 1196 LKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255

Query: 107  IKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVS 166
              +   + V ELE+  DDL         ++++ +      +ER    E E+++ ++ ++ 
Sbjct: 1256 EWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLE 1315

Query: 167  VQRLKDEARDLRQELAVRERQ-------QEVTRKSAPSSPTLDC 203
            +QR  D      QEL  RE Q       Q + RK A  +   +C
Sbjct: 1316 LQRKLDNTTAAVQELG-RENQSLQIKHTQALNRKWAEDNEVQNC 1358



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 54/218 (24%), Positives = 103/218 (47%), Gaps = 38/218 (17%)

Query: 12  LKEETAYWKELSL---KYKQSFQEAR----DELVEFQEGSRELEAELEAQLVQAEQRNRD 64
           LKE+     EL     K KQ  QE +        + +E   +LE  L  Q+   +Q+ ++
Sbjct: 469 LKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLR-QIGDKDQKIQN 527

Query: 65  LQADNQRLKYEVEALKEKLEHQYA-------------QSYKQVSVLEDDLSQ-TRAIKEQ 110
           L+A  Q+ K  +  L+++ E  YA             Q  ++   L++ ++Q T  +K Q
Sbjct: 528 LEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQ 587

Query: 111 LHKYVRELEQANDDLE------RAKRATIVSLE----DFEQRLNQAIERNAFLESELDEK 160
              + +  E  +D ++      RA +  ++SLE    +   +LN++ E+ + L+ ++  K
Sbjct: 588 SESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAK 647

Query: 161 ESLLVSVQRLKDEAR-DLRQEL-----AVRERQQEVTR 192
             LL+S +  K   R DL+  L     A++++QQE+ +
Sbjct: 648 TELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNK 685



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 18/184 (9%)

Query: 12   LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEA---QLVQAEQRNRDLQAD 68
            LK +     E +LK ++   E +  L + +E S +L+ EL +   QL+QA+   +  + +
Sbjct: 897  LKHQLQVQMENTLKEQK---ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKE 953

Query: 69   NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQL-HKYVRELEQANDDLER 127
             Q+L+  +  LK+  E    Q  KQ+  L+ +L      K +L +K  ++L QA  +L  
Sbjct: 954  EQQLQGNINELKQSSE----QKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAA 1009

Query: 128  AKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-LLVSVQRLK--DEARDLRQELAVR 184
             K    V   ++E    ++ E    L+S+   +ES LL + Q LK  +E   L QE  + 
Sbjct: 1010 EKEKISVLQNNYE----KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLIS 1065

Query: 185  ERQQ 188
             R Q
Sbjct: 1066 NRNQ 1069



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 41/181 (22%), Positives = 87/181 (48%), Gaps = 24/181 (13%)

Query: 41  QEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEK---LEHQYAQSYKQVSVL 97
           Q+  +EL  ++  QL Q   + +D Q    +L+  ++  KEK   LE +  +   Q+  L
Sbjct: 677 QDKQQELN-KITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKL 735

Query: 98  EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESEL 157
           E D  + +A KEQ  + +++  Q N DLE   RAT +S +               LE E 
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLE--LRATELSKQ---------------LEMEK 778

Query: 158 DEKESLLVSVQRLKDEARDLRQELAVRERQQEVTR---KSAPSSPTLDCEKMDSAVQASL 214
           +   S  + +Q+  +    ++Q+L  +E ++++ +   ++      +  E++++ +Q ++
Sbjct: 779 EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTV 838

Query: 215 S 215
           +
Sbjct: 839 T 839



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 45/208 (21%), Positives = 87/208 (41%), Gaps = 26/208 (12%)

Query: 10  SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
           + L ++     E  LK +Q + +  ++  E     + ++A L  + +  +Q    L A  
Sbjct: 298 NELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASE 357

Query: 70  -----------------QRLKYEVEALKEKLEH---QYAQSYKQVSVLEDDLSQTRAIKE 109
                            Q+LK E+  ++ K +H   ++ Q  +Q    E    Q ++   
Sbjct: 358 TSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEIN 417

Query: 110 QLHKYV----RELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLV 165
           QLH  +    R+L +A+  L+  ++ +   L D EQ++     + + LE +L EK +   
Sbjct: 418 QLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNST 477

Query: 166 SVQRLKDEARDLRQELAVRERQQEVTRK 193
            +Q   D+ +   QE   +  QQ  T K
Sbjct: 478 ELQHQLDKTKQQHQE--QQALQQSTTAK 503



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 38/183 (20%), Positives = 81/183 (44%), Gaps = 34/183 (18%)

Query: 31  QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQS 90
           Q+ + EL+  Q    E  A L+ +LVQ +    ++  + +R   +++   +KL+ QYA S
Sbjct: 208 QDLKTELL--QRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASS 265

Query: 91  YKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERN 150
              +S L  +L++     +++  YV+EL++                   +  +N+  ++N
Sbjct: 266 EATISQLRSELAKG---PQEVAVYVQELQK------------------LKSSVNELTQKN 304

Query: 151 AFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAV 210
             L   L +KE     ++   +E    ++ +     Q++           LDC+++ S +
Sbjct: 305 QTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKD-----------LDCQQLQSRL 353

Query: 211 QAS 213
            AS
Sbjct: 354 SAS 356



 Score = 36.6 bits (83), Expect = 0.034
 Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 25/145 (17%)

Query: 60  QRNRDLQADNQRLKYEVEALKEKLEHQYA---QSYKQVSVLEDDLSQTRAIKEQLHKYVR 116
           Q  +DLQA  +  K+  E LK++LE       Q  K   ++ D  ++ +++++QL     
Sbjct: 90  QEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLE---- 145

Query: 117 ELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVS----VQRLKD 172
           E +  N ++++ K       + FEQ+  Q     A ++S+ DE+ SL  +    V RL +
Sbjct: 146 EAQTENFNIKQMK-------DLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTE 198

Query: 173 E-------ARDLRQELAVRERQQEV 190
           E        +DL+ EL  R   ++V
Sbjct: 199 ELNKEATVIQDLKTELLQRPGIEDV 223



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 35/193 (18%), Positives = 86/193 (44%), Gaps = 29/193 (15%)

Query: 34   RDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEA-----------LKEK 82
            +D+L +  +  +  ++E E +  + +    DL+   + LK++++            LK+ 
Sbjct: 859  KDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKS 918

Query: 83   LEHQYAQSY----------KQVSVLEDDLSQTRAIKEQLHKYVRELEQANDD-------L 125
            LE +   S+          +Q+   ++ L Q    ++QL   + EL+Q+++        L
Sbjct: 919  LEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEAL 978

Query: 126  ERAKRATIVSLEDFEQRLNQAIERNA-FLESELDEKESLLVSVQRLKDEARDLRQELAVR 184
            +   +  ++   + E +L Q + + A  L +E ++   L  + ++ ++  + L+ +   R
Sbjct: 979  QGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGR 1038

Query: 185  ERQQEVTRKSAPS 197
            E +   TR+   S
Sbjct: 1039 ESELLATRQDLKS 1051



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 40/183 (21%), Positives = 78/183 (42%), Gaps = 20/183 (10%)

Query: 23  SLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA---DNQRLKYEVEAL 79
           S+K K + QE   ++++     ++ E   +   +Q E+ N  +Q    + Q++K E EAL
Sbjct: 797 SIKQKLTKQEEEKQILK-----QDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEAL 851

Query: 80  -------KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
                  K+KL           S  E +  + +A    L K  +EL+     L+     T
Sbjct: 852 MTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKH---QLQVQMENT 908

Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELA--VRERQQEV 190
           +   ++ ++ L +  E +  L+ EL+  +  L+  Q    +     Q+L   + E +Q  
Sbjct: 909 LKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSS 968

Query: 191 TRK 193
            +K
Sbjct: 969 EQK 971


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 46/204 (22%), Positives = 91/204 (44%), Gaps = 19/204 (9%)

Query: 29  SFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYA 88
           + Q+   EL   ++ ++E +A+L   L Q EQ ++ L+   ++L     +LK+K +    
Sbjct: 513 TIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLS---SSLKQKEQQLKE 569

Query: 89  QSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRL----- 143
            + KQ +  +D   Q     E+    +RE + A   LE  ++     LE  +Q+L     
Sbjct: 570 VAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANE 629

Query: 144 ---------NQAIERNAFLESELDEKESLLVSVQRLKDEARD--LRQELAVRERQQEVTR 192
                     QA    A L  +++E ++ + + ++ + EA+      EL +R  QQ+ T 
Sbjct: 630 ARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATE 689

Query: 193 KSAPSSPTLDCEKMDSAVQASLSL 216
           K   +      ++   A++ SL +
Sbjct: 690 KERVAQEKDQLQEQLQALKESLKV 713



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 43/188 (22%), Positives = 80/188 (42%), Gaps = 9/188 (4%)

Query: 13  KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
           +EE      L    + S         E ++ S+   A L AQ+         L A  Q+ 
Sbjct: 458 EEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQ 517

Query: 73  KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
             E+  LK++ + + AQ  + +   E      R   EQL   +++ EQ   ++   + AT
Sbjct: 518 DQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEAT 577

Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTR 192
               +D  Q+L  A E     E+ L E+++ L  ++ L+ E      +L + ++Q +V  
Sbjct: 578 ---RQDHAQQLATAAEER---EASLRERDAALKQLEALEKEK---AAKLEILQQQLQVAN 628

Query: 193 KSAPSSPT 200
           ++  S+ T
Sbjct: 629 EARDSAQT 636



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 11/175 (6%)

Query: 20  KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEAL 79
           ++LS   KQ  Q+ + E+ E QE +R+  A+  A    AE+R   L+  +  LK ++EAL
Sbjct: 554 EQLSSSLKQKEQQLK-EVAEKQEATRQDHAQQLA--TAAEEREASLRERDAALK-QLEAL 609

Query: 80  -KEK------LEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
            KEK      L+ Q   + +     +  ++Q +  K +L + V EL+   +   + +   
Sbjct: 610 EKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEA 669

Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
              + + E +L    ++    E    EK+ L   +Q LK+  +  +  L   +R+
Sbjct: 670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR 724



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 57/220 (25%), Positives = 93/220 (42%), Gaps = 23/220 (10%)

Query: 6   IPDFSSLKEETAYWKELSLKYKQSFQEARDELV--------EFQEGSRELEAELEAQLVQ 57
           +    +L++E A   E+  +  Q   EARD           E  E SR++E EL+A +  
Sbjct: 603 LKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVE-ELQACVET 661

Query: 58  AEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDL-SQTRAIKEQLHKYVR 116
           A Q   + QA    L+ ++ +     E Q A   ++V+  +D L  Q +A+KE L     
Sbjct: 662 ARQEQHEAQAQVAELELQLRS-----EQQKATEKERVAQEKDQLQEQLQALKESLKVTKG 716

Query: 117 ELEQ----ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKD 172
            LE+    A D LE  +R       +    + Q       LE E   ++ L   +Q+L  
Sbjct: 717 SLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQL-G 775

Query: 173 EARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQA 212
           EA     E+  RE  + +  +    S   +CE++   V A
Sbjct: 776 EAHQAETEVLRRELAEAMAAQHTAES---ECEQLVKEVAA 812



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 44/245 (17%)

Query: 12  LKEETAYWKELSLKYKQSFQE----ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA 67
           L+E+    KE     K S +E    A D L E Q    EL+AE  + + Q ++  ++L+ 
Sbjct: 700 LQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEE 759

Query: 68  DNQRLK--------------YEVEALKEKLEHQYAQSYKQVSVLE-------------DD 100
           +    K               E E L+ +L    A  +   S  E             +D
Sbjct: 760 ERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYED 819

Query: 101 LSQTRA-----IKEQLHKYVRELEQANDDLERAKR--ATIVSLEDFE--QRLNQAIERNA 151
             Q  A      +EQL     E E+A  +L+ AK   A I S  + +  ++ N+  E +A
Sbjct: 820 SQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHA 879

Query: 152 FLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ----QEVTRKSAPSSPTLDCEKMD 207
            L   L + +   V  Q+L D+   L++++A   ++    + + RK+     T   E + 
Sbjct: 880 NLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVK 939

Query: 208 SAVQA 212
              +A
Sbjct: 940 EPARA 944



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 54/197 (27%), Positives = 92/197 (46%), Gaps = 24/197 (12%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE--------AELEAQLVQAEQRNRD 64
            +E+    KE   K +Q  QEA++++   +  S EL+        AEL A L +A Q+ ++
Sbjct: 832  QEQLMTLKEECEKARQELQEAKEKVAGIESHS-ELQISRQQNELAELHANLARALQQVQE 890

Query: 65   LQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDL-----SQTRAIKEQLHKYVRELE 119
             +   Q+L  ++  L+EK+    A + K+V+ LE  +      Q  A +E + +  R  +
Sbjct: 891  KEVRAQKLADDLSTLQEKM----AATSKEVARLETLVRKAGEQQETASRELVKEPARAGD 946

Query: 120  QANDDLERAKRATIVSLEDFEQRLNQAIERNA-FLESELDEKESLLVSVQRLKDEARDLR 178
            +  + LE  +     S     Q   QA+ER A  + +EL+   + L+  Q  + E R  +
Sbjct: 947  RQPEWLEEQQGRQFCS----TQAALQAMEREAEQMGNELERLRAALMESQGQQQEERG-Q 1001

Query: 179  QELAVRERQQEVTRKSA 195
            QE  V    QE  R  A
Sbjct: 1002 QEREVARLTQERGRAQA 1018



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)

Query: 34  RDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKY------EVEALKEKLEHQY 87
           RDEL      +R+L  E +AQ+   +QR   L   N++         E+E L++K E   
Sbjct: 230 RDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLT 289

Query: 88  AQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAI 147
            + ++ +   +D     +  K Q+ + + +L + N DL    R     L+  +  LN+  
Sbjct: 290 MRLHETLKQCQD----LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345

Query: 148 ERNAFLESELDEKESLL 164
           E ++    E  EK++ L
Sbjct: 346 EEHSKATQEWLEKQAQL 362



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 51/191 (26%), Positives = 89/191 (46%), Gaps = 28/191 (14%)

Query: 21  ELSLKYKQ---SFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR------DLQADNQR 71
           ELS K ++     + AR E  E Q    ELE +L ++  +A ++ R       LQ   Q 
Sbjct: 647 ELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQA 706

Query: 72  LKYEVEALKEKLEHQYAQSY----KQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER 127
           LK  ++  K  LE +  ++     +Q   + +  ++TR++ EQ  +  +ELE+     ER
Sbjct: 707 LKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEE-----ER 761

Query: 128 AKRATIVSLEDFEQRLNQAIERNAFLESELDEKE--SLLVSVQRLKDEARDLRQELAV-R 184
           A R      +  E RL Q  E +   E+E+  +E    + +    + E   L +E+A  R
Sbjct: 762 AGR------KGLEARLQQLGEAHQ-AETEVLRRELAEAMAAQHTAESECEQLVKEVAAWR 814

Query: 185 ERQQEVTRKSA 195
           ER ++  ++ A
Sbjct: 815 ERYEDSQQEEA 825



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 70/317 (22%), Positives = 138/317 (43%), Gaps = 37/317 (11%)

Query: 13   KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
            +E+T   +ELS K   S Q ++ +        ++L+A ++AQ  +++Q  + LQA    L
Sbjct: 1545 REQTKQVEELSKKLADSDQASKVQ-------QQKLKA-VQAQGGESQQEAQRLQAQLNEL 1596

Query: 73   KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
            + ++   ++  EH   Q  K  +  +    Q + ++EQL + + +L++ N +L RA+   
Sbjct: 1597 QAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQL-RSLEQLQKENKEL-RAE--- 1651

Query: 133  IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTR 192
                    +RL   +++      E ++      + + L  + R L  ++A  ++Q     
Sbjct: 1652 -------AERLGHELQQAGLKTKEAEQ------TCRHLTAQVRSLEAQVAHADQQLRDLG 1698

Query: 193  KSAPSSPTLDCEKMDSAVQASLSLPATPVG--KGTENTFPS--PKAIPNGFGTSPLTPSA 248
            K   ++  L   +  +  Q  LS+ +  +   +GT  +  S  P+  P+G    P  P++
Sbjct: 1699 KFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSV-PGEPAS 1757

Query: 249  RISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNGTKFSRSGH 308
             IS       L  KV +LES L      A+ QA  +S +    +  + +G  T+ +R   
Sbjct: 1758 PISQ-----RLPPKVESLES-LYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSARRRT 1811

Query: 309  TSFFDKGAVNGFDPAPP 325
            T   +       D   P
Sbjct: 1812 TQIINITMTKKLDVEEP 1828



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 32/152 (21%), Positives = 67/152 (44%), Gaps = 10/152 (6%)

Query: 38   VEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVL 97
            VE  +   +   EL A    AE R  ++Q + Q    E+E +  K E    +  ++    
Sbjct: 1467 VELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1526

Query: 98   EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESEL 157
            +++  +  A  EQL  + RE  +  ++L +        L D +Q      ++   ++++ 
Sbjct: 1527 QEERQKLTAQVEQLEVFQREQTKQVEELSK-------KLADSDQASKVQQQKLKAVQAQG 1579

Query: 158  DEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
             E +      QRL+ +  +L+ +L+ +E+  E
Sbjct: 1580 GESQQ---EAQRLQAQLNELQAQLSQKEQAAE 1608



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 50/207 (24%), Positives = 89/207 (42%), Gaps = 21/207 (10%)

Query: 10   SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
            SSL+EE +      L+ +   +E +  ++   E S++LE  L  +L+QAE  +   +A  
Sbjct: 1228 SSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERL--RLLQAETASNSARAAE 1285

Query: 70   QR--LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVREL---EQANDD 124
            +   L+ EV++L+E+ E Q   S      L     +   + ++L  +  +    EQA   
Sbjct: 1286 RSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALST 1345

Query: 125  LE---RAKRATIVSLEDFEQRLNQAIERNAFLE----SELDEKESL-------LVSVQRL 170
            L+    + +A +  L   +    Q     A  E     EL++ +         L+  QR 
Sbjct: 1346 LQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRE 1405

Query: 171  KDEARDLRQELAVRERQQEVTRKSAPS 197
              E   LRQ++A +ER  +  R    S
Sbjct: 1406 LGELIPLRQKVAEQERTAQQLRAEKAS 1432



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 39/165 (23%), Positives = 74/165 (44%), Gaps = 28/165 (16%)

Query: 39   EFQEGSRELE---AELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
            E Q  +RELE   A+ E   V+  +  +  Q + Q+L  +VE L E  + +  +  +++S
Sbjct: 1497 EAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQL-EVFQREQTKQVEELS 1555

Query: 96   VLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLES 155
                D  Q   +++Q  K V+   Q  +  + A+R         + +LN+       L++
Sbjct: 1556 KKLADSDQASKVQQQKLKAVQA--QGGESQQEAQR--------LQAQLNE-------LQA 1598

Query: 156  ELDEKESLL----VSVQRLK---DEARDLRQELAVRERQQEVTRK 193
            +L +KE       + +++ K   D  +   QEL  + R  E  +K
Sbjct: 1599 QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQK 1643


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 50/189 (26%), Positives = 96/189 (50%), Gaps = 22/189 (11%)

Query: 24   LKYKQSFQEARDELV-EFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEK 82
            +K   S Q  RD +V ++Q+    LE    + +++ +Q  ++  A+N +LK E+  L+  
Sbjct: 2463 VKSMSSLQNDRDRIVGDYQQ----LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSH 2518

Query: 83   LEHQYAQSYK---QVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLERAKRATIVSLED 138
            ++   +++ K   ++    +DL+Q   IK+   K + E++ Q N +LE         L++
Sbjct: 2519 MDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKE 2578

Query: 139  FEQRLNQAIER--NAFLESELD---EKESLLVSVQRLKDEARDLRQE-------LAVRER 186
             E+  N+ + R  NA  E + D   E ESL VS+ +L  +   L++E         ++ +
Sbjct: 2579 SEE-ANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVK 2637

Query: 187  QQEVTRKSA 195
            ++EV R SA
Sbjct: 2638 EEEVHRLSA 2646



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 64/282 (22%), Positives = 119/282 (42%), Gaps = 46/282 (16%)

Query: 10   SSLKEETAYW----KELSLKYK---QSFQEARDELVEFQ---EGSRELEAELEAQLVQAE 59
            SS   E+  W    KEL  +Y+   QS++   +E    Q   E  R+ + EL  +L   E
Sbjct: 1595 SSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTE 1654

Query: 60   QRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE 119
               ++ +   Q  + E+E +KEK+  ++A+S KQ  +LE        ++E+  +   E+ 
Sbjct: 1655 ANKKETEKQLQEAEQEMEEMKEKM-RKFAKS-KQQKILE--------LEEENDRLRAEVH 1704

Query: 120  QANDDLERAKRATIVSLEDFEQRLNQAIERNAFL----ESELDEKESLLVSVQRLKDEAR 175
             A D  +      + S    ++ L +       L    +S + EK+SL   VQ LK +  
Sbjct: 1705 PAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIE 1764

Query: 176  DLRQELA------VRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTF 229
                + A        + Q  VT +   S P       ++  Q SLS+   P         
Sbjct: 1765 GNVSKQANLEATEKHDNQTNVTEEGTQSIPG------ETEEQDSLSMSTRPT-------- 1810

Query: 230  PSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLA 271
               +++P+    +P   S   S+ + + + L+++  L+ ++A
Sbjct: 1811 -CSESVPSAKSANPAV-SKDFSSHDEINNYLQQIDQLKERIA 1850



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 54/262 (20%), Positives = 120/262 (45%), Gaps = 35/262 (13%)

Query: 21  ELSLKYKQSFQEARDELVEFQE---GSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVE 77
           ++  + +Q  +  + +L E +E   G  ++   L+ +L  AEQRN+ L    Q+++ E  
Sbjct: 245 DVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHN 304

Query: 78  ALKEKLEHQYAQSYKQVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKRATI 133
            L+  +E +  +S   +  +E ++++ +     ++E++H  + + EQA            
Sbjct: 305 TLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQ---------- 354

Query: 134 VSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLK-------DEARDLRQELAVRER 186
            +  + E R +   +++   ++E++EK S ++S+Q+         D  +D   +L   + 
Sbjct: 355 -AQAELESRYSALEQKH---KAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKN 410

Query: 187 QQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGF--GTSPL 244
           +Q V  +SA +   L+ +    + + S  L   P+    ++   S  + P+ +  GT  +
Sbjct: 411 EQAV--QSAQTIQQLEDQLQQKSKEISQFLNRLPL---QQHETASQTSFPDVYNEGTQAV 465

Query: 245 TPSARISALNIVGDLLRKVGAL 266
           T     S    V +L  + GAL
Sbjct: 466 TEENIASLQKRVVELENEKGAL 487



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 47/186 (25%), Positives = 84/186 (45%), Gaps = 35/186 (18%)

Query: 29  SFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR-----------DLQADNQRLKYEVE 77
           + QE    L+E  E + + +AELE++    EQ+++            LQ   Q L+   +
Sbjct: 337 NLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACD 396

Query: 78  ALKEK-------LEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKR 130
           ALK++          Q  QS + +  LED L Q     +++ +++  L      L++ + 
Sbjct: 397 ALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQK---SKEISQFLNRL-----PLQQHET 448

Query: 131 ATIVSLEDFEQRLNQAI--ERNAFLESEL----DEKESLLVS---VQRLKDEARDLRQEL 181
           A+  S  D      QA+  E  A L+  +    +EK +LL+S   ++ LK E   L  ++
Sbjct: 449 ASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI 508

Query: 182 AVRERQ 187
            + E Q
Sbjct: 509 TLLEAQ 514



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 43/183 (23%), Positives = 92/183 (50%), Gaps = 10/183 (5%)

Query: 20   KELSLKYKQSFQEARDELVEFQEGSRELEAELEA-QLVQAEQRNRDLQADNQRLKYEVEA 78
            +EL  + +Q  ++ + + + +QE    LE  ++A + VQ E + +DL+   + L   VE 
Sbjct: 2011 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQ-KDLEITKENLAQAVEH 2069

Query: 79   LKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLED 138
             ++K + + A S+K   +L+D  S+   +     K  +EL+    + E  K       ED
Sbjct: 2070 -RKKAQAELA-SFK--VLLDDTQSEAARVLADNLKLKKELQ---SNKESVKSQMKQKDED 2122

Query: 139  FEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPS 197
             E+RL QA E++   +  + EK ++L      L++   +++  L  ++++ +  +++  S
Sbjct: 2123 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2182

Query: 198  SPT 200
            + T
Sbjct: 2183 TVT 2185



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 40/166 (24%), Positives = 76/166 (45%), Gaps = 30/166 (18%)

Query: 36   ELVEFQ-EGSRELE---AELEAQLVQAEQRNRDL-------QADNQRLKYEVEALKEKLE 84
            +L+E Q + ++ELE   A+LE +L ++E+ N DL       Q + Q L  E+E+LK  + 
Sbjct: 2553 QLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSIS 2612

Query: 85   HQYAQS------------YKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
                Q             + Q+ V E+++ +  A+     K + ELE+    +++     
Sbjct: 2613 QLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKK 2672

Query: 133  IVSLED-FEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
            +  +ED  ++ L         + +E +  E      +R+ + ARDL
Sbjct: 2673 VGEIEDKLKKELKHLHHDAGIMRNETETAE------ERVAELARDL 2712



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 47/201 (23%), Positives = 93/201 (46%), Gaps = 18/201 (8%)

Query: 4    EDIPDFSSLKE-ETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRN 62
            E++    S KE E     +L L+ K+  +  +  + E  +   E+   +  ++VQ  +  
Sbjct: 862  EELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 921

Query: 63   RDLQADNQRLKYEV-------EALKEKLE--HQYAQSYKQVSVLEDDLSQTRAI-KEQLH 112
              L  + + LK ++       EA KE++E  ++ +   KQ     D++S    I KE+L 
Sbjct: 922  FSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNY---DEMSPAGQISKEELQ 978

Query: 113  KYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQR--- 169
                 L++ N+  +R  +A +++ ++  QR+++  E  A L+ E  +KE  L   +R   
Sbjct: 979  HEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE-SKKEIPLSETERGEV 1037

Query: 170  LKDEARDLRQELAVRERQQEV 190
             +D+      E  V  + QE+
Sbjct: 1038 EEDKENKEYSEKCVTSKCQEI 1058



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 6/182 (3%)

Query: 8    DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA 67
            + + L+ E    K+       S ++ +++    +   R+ EA+++      EQ   DLQA
Sbjct: 2306 ELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQA 2365

Query: 68   DNQ---RLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQ--TRAIKEQLHKYVRELEQAN 122
              +   RL  E+   ++K+    +   + + V   +L Q   + IKE L   + + E+ N
Sbjct: 2366 SRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKE-LENLLSQEEEEN 2424

Query: 123  DDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELA 182
              LE   +  +       + L    + N   +++LD     + S+Q  +D      Q+L 
Sbjct: 2425 IVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE 2484

Query: 183  VR 184
             R
Sbjct: 2485 ER 2486



 Score = 35.8 bits (81), Expect = 0.058
 Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 16/187 (8%)

Query: 42   EGSRELEAELEAQLVQAEQR-------NRDLQADNQRLKYEVEALKEKLEHQYAQSYKQV 94
            E + E  AEL   LV+ EQ+       N+ L A  Q     + +L+   +H   +  +  
Sbjct: 2699 ETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELK 2758

Query: 95   SVLEDDLSQTRAIKEQ-LHKYVRE--LEQANDDLERAKRATIVSLEDFEQRL----NQAI 147
               +  L +   +KEQ L    R+  L +    +   +  ++  LE   Q+L     Q +
Sbjct: 2759 RKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLL 2818

Query: 148  ERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSA--PSSPTLDCEK 205
              ++ LE   ++ +S   ++  L++E   L  EL    + +E  ++SA  PS+   + + 
Sbjct: 2819 HLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQS 2878

Query: 206  MDSAVQA 212
            +  A+ +
Sbjct: 2879 LKKAMSS 2885



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 56/247 (22%), Positives = 99/247 (40%), Gaps = 42/247 (17%)

Query: 11   SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQ------------LVQA 58
            +LKE  +  +ELSL        AR  +    +   ++E+++ AQ            L+Q 
Sbjct: 1495 ALKENKSLQEELSL--------ARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1546

Query: 59   EQRNRDLQAD-----NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHK 113
            E+     + D     NQ L    E+LK  LE       K V  +E   S   A   +  +
Sbjct: 1547 ERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQE 1606

Query: 114  YVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDE 173
              +EL++  + L          L+ +E   N+A      +E+   EK+ L   ++  +  
Sbjct: 1607 KHKELQKEYEIL----------LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEAN 1656

Query: 174  ARDLRQELAVRERQ----QEVTRKSAPS--SPTLDCEKMDSAVQASLSLPATPVGKGTEN 227
             ++  ++L   E++    +E  RK A S     L+ E+ +  ++A +  PA    K    
Sbjct: 1657 KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVH-PAGDTAKECME 1715

Query: 228  TFPSPKA 234
            T  S  A
Sbjct: 1716 TLLSSNA 1722



 Score = 32.3 bits (72), Expect = 0.64
 Identities = 45/236 (19%), Positives = 98/236 (41%), Gaps = 39/236 (16%)

Query: 10   SSLKEETAYWKELSLKYKQSFQEA---RDELVEFQEGS--------RELEAELEAQLVQA 58
            SSL+++     + + K+++ F +A   ++E +  +E +        R++   +E   +  
Sbjct: 2195 SSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINI 2254

Query: 59   EQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVREL 118
             +   D Q    + + EV+  ++  +    ++ + +S LE+      + + +L K   EL
Sbjct: 2255 SRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESEL 2314

Query: 119  EQANDDLE--------------------RAKRATI----VSLEDFEQRLNQAIERNAFLE 154
            +   D L                     R + A I     S E  E  L  + E  + L 
Sbjct: 2315 KSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLH 2374

Query: 155  SELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAV 210
             E++ KE  ++S+   K+EA     ++A+ E +Q+  ++       L  E+ ++ V
Sbjct: 2375 EEINMKEQKIISLLSGKEEA----IQVAIAELRQQHDKEIKELENLLSQEEEENIV 2426



 Score = 32.0 bits (71), Expect = 0.83
 Identities = 39/179 (21%), Positives = 69/179 (38%), Gaps = 18/179 (10%)

Query: 27   KQSFQEARDELVEFQEGSRELEAE---LEAQLVQAEQRNRDLQADNQRLKYEVEALKEKL 83
            K   QE +D+   FQ    EL  E    + +L Q        +   +R+K +        
Sbjct: 2918 KAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDK 2977

Query: 84   EHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDD--------LERAKRATIVS 135
            + Q +     +  L    SQT+ +K Q  +       A+ D         E  +     S
Sbjct: 2978 DQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDS 3037

Query: 136  LEDFEQRLNQAIERNAFLESELDEKESLLVSV----QRLKDEAR---DLRQELAVRERQ 187
            L++  Q+  +  + N+     L+EK +L + +    Q L++  +   DL    AV E+Q
Sbjct: 3038 LKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQ 3096



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 36/168 (21%)

Query: 32   EARDELVEFQEGSRELEAELEAQLVQAEQRNRDL-----QADNQRLKYEVEALKEKLEHQ 86
            EA   L +  +  +EL++  E+   Q +Q++ DL     QA+ + LK E + ++EKL+  
Sbjct: 2090 EAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK-EKKNMQEKLDAL 2148

Query: 87   YAQSY-----------------KQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK 129
              +                   K+V  L+++L  T     QL  + + +    DD +R  
Sbjct: 2149 RREKVHLEETIGEIQVTLNKKDKEVQQLQENLDST---VTQLAAFTKSMSSLQDDRDR-- 2203

Query: 130  RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
               I   + +E++ + AI+     E E+  KE    +   LKD+ R +
Sbjct: 2204 --VIDEAKKWERKFSDAIQSK---EEEIRLKED---NCSVLKDQLRQM 2243



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 13/72 (18%)

Query: 38  VEFQEGSRELEAELEAQLVQAEQRNRDLQAD------------NQRLKYEVEALKEKLEH 85
           +E +E   E E +L +Q+   E +NR  +AD            N+R     E+ ++ LE+
Sbjct: 492 IELEELKAENE-KLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLEN 550

Query: 86  QYAQSYKQVSVL 97
            ++Q +K++SVL
Sbjct: 551 TFSQKHKELSVL 562


>gi|149363685 hypothetical protein LOC23379 [Homo sapiens]
          Length = 2266

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 84/371 (22%), Positives = 148/371 (39%), Gaps = 74/371 (19%)

Query: 10  SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE------AELEAQLVQAEQRNR 63
           +SL++    + E  +  KQ      + L E+Q+   EL+      + L  Q+ +  Q+  
Sbjct: 24  ASLQQNLNEYVEALITLKQKIINTDNLLTEYQKKCDELQFARRENSNLHHQVEEMLQKIS 83

Query: 64  DLQADNQRL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
            LQ   + L   K E+E  K  L+  Y  ++++ + ++++  ++ A K++L   V++L++
Sbjct: 84  PLQKCQEELGSLKAELEEKKSSLK-LYQDTHQEYARVKEECLKSDAQKKKLEAKVKKLQE 142

Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
           A           +   +DF+Q  N+       LE E  + +  L    + K+E       
Sbjct: 143 A----------AVKQTQDFKQLRNE----KKILEKEFKKTQERLDEFSKQKNE------- 181

Query: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDS-------AVQASLSLPATPVGKGTENTFPSP- 232
              +E +   T+ S+ S  ++D  K+          V  +  LP    G+G+      P 
Sbjct: 182 ---KELRHIGTQISSDSYGSIDKRKVKLLLKELWLCVNTTHRLP----GEGSRCVPEKPA 234

Query: 233 -----KAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYI 287
                  +P   GT P T  + +   N V   L K+     +   C+N  K  +S  +  
Sbjct: 235 KAITSSRVPGEDGTLPPTQGSPLRTSN-VQTCLTKLSMEIKEDFLCQNVEKQSSSGTNCS 293

Query: 288 SGNV-----NCGVL-----NGNGTKFSRSGHTSFFDKGAVNGFD----------PAPPPP 327
           S +V     N  VL     +G  T+F    H  FFD+      D          P P PP
Sbjct: 294 SDHVFNENGNLEVLVQSHRDGGSTEFV--DHDHFFDEDLQAAIDFFKLPPPLLSPVPSPP 351

Query: 328 GLGSSRPSSAP 338
            + S  P S P
Sbjct: 352 PMSSPHPGSLP 362


>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
          Length = 541

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 63/294 (21%), Positives = 127/294 (43%), Gaps = 31/294 (10%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           ++E     +E++++YKQ  ++  +EL   +    +L+ +   +     + +R+ +++ +R
Sbjct: 82  VEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHREDRSEIER 141

Query: 72  LKYEVEALKEK---LEHQYAQSYKQVSVLEDD----LSQTRAIKEQLHKYVRELEQA--- 121
           L  ++E  ++K    E Q     +QVS LE        Q+  I+ QL    ++LE     
Sbjct: 142 LTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELS 201

Query: 122 --------NDDLERAKR---ATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRL 170
                   +  LERA     A  + +E    R+N  +  +  +  E  +KE  L   ++L
Sbjct: 202 SQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKL 261

Query: 171 KDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFP 230
            +  ++ ++EL    + QE     A     +  EK+   V+A+ +  A    +  E +  
Sbjct: 262 LEALQEEKRELKAALQSQENLIHEA----RIQKEKLQEKVKATNTQHAVEAIRPREESLA 317

Query: 231 SPKAIPNGFGTSPLTPSARISALNIVGDLLRK-----VGALESKLAACRNFAKD 279
             K    G G      S +++  +   DLL+       G+LES  A C+  +++
Sbjct: 318 EKKYTSQGQGDLDSVLS-QLNFTHTSEDLLQAEVTCLEGSLESVSATCKQLSQE 370


>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
          Length = 703

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 63/294 (21%), Positives = 127/294 (43%), Gaps = 31/294 (10%)

Query: 12  LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
           ++E     +E++++YKQ  ++  +EL   +    +L+ +   +     + +R+ +++ +R
Sbjct: 82  VEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHREDRSEIER 141

Query: 72  LKYEVEALKEK---LEHQYAQSYKQVSVLEDD----LSQTRAIKEQLHKYVRELEQA--- 121
           L  ++E  ++K    E Q     +QVS LE        Q+  I+ QL    ++LE     
Sbjct: 142 LTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELS 201

Query: 122 --------NDDLERAKR---ATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRL 170
                   +  LERA     A  + +E    R+N  +  +  +  E  +KE  L   ++L
Sbjct: 202 SQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKL 261

Query: 171 KDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFP 230
            +  ++ ++EL    + QE     A     +  EK+   V+A+ +  A    +  E +  
Sbjct: 262 LEALQEEKRELKAALQSQENLIHEA----RIQKEKLQEKVKATNTQHAVEAIRPREESLA 317

Query: 231 SPKAIPNGFGTSPLTPSARISALNIVGDLLRK-----VGALESKLAACRNFAKD 279
             K    G G      S +++  +   DLL+       G+LES  A C+  +++
Sbjct: 318 EKKYTSQGQGDLDSVLS-QLNFTHTSEDLLQAEVTCLEGSLESVSATCKQLSQE 370



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 40/186 (21%), Positives = 77/186 (41%), Gaps = 27/186 (14%)

Query: 11  SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
           SL+  +A  K+LS    Q   E  +EL   +  + E +AE++    Q  Q  +   +  +
Sbjct: 356 SLESVSATCKQLS----QELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQSYSSALE 411

Query: 71  RLKYEVEALKEKLEHQ--------------YAQSYKQVSVLEDDLSQTRAIKEQLHKYVR 116
            +K E+  L ++L  +                +   ++   ED   + + I +QL     
Sbjct: 412 GMKMEISHLTQELHQRDITIASTKGSSSDMEKRLRAEMQKAEDKAVEHKEILDQLESLKL 471

Query: 117 ELEQAND-------DLERAKRATIVSL-EDFEQRLNQAIERNAFLESEL-DEKESLLVSV 167
           E    ++        L  AK  ++  L E++ + LN+ +  N  L+ +L + K  L +S 
Sbjct: 472 ENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMNTKSQLEIST 531

Query: 168 QRLKDE 173
           Q  K +
Sbjct: 532 QMCKKQ 537


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 44/188 (23%), Positives = 87/188 (46%), Gaps = 15/188 (7%)

Query: 22  LSLKYKQSFQEARD-ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALK 80
           L L+ K+SF   +  +L +  E    L  E+       E + R +    ++++   E L+
Sbjct: 497 LRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLR 556

Query: 81  EKLEHQYAQSYKQVSVLEDDLSQT----RAIKEQLHKYVRELEQANDDLERAKRATIVSL 136
           +K + Q      +V  L+ D S T      ++E L +  R +E+  +  ER  R  +  +
Sbjct: 557 DK-DKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEI 615

Query: 137 EDFEQRLNQAIERNAFLESELDEKESLLVSVQR---------LKDEARDLRQELAVRERQ 187
           E F +      E+   L++EL EKES L+ ++          LK +++    E+A+ +++
Sbjct: 616 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 675

Query: 188 QEVTRKSA 195
           +E ++  A
Sbjct: 676 EECSKLEA 683



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 45/201 (22%), Positives = 90/201 (44%), Gaps = 23/201 (11%)

Query: 4   EDIPDFSSLKEETAYWKELSLKYKQSFQEARD-ELVEFQEGSRELEAELEAQ----LVQA 58
           E++   S L+ E A  K L     Q+  E +D ++   +   R+LE E++      ++  
Sbjct: 358 EELHRRSQLQPEPAKTKAL-----QTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNT 412

Query: 59  EQRNRDLQ------ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLH 112
           E R  +++      + ++ +K +++ LK++L  + ++     + LE   +Q    K+ + 
Sbjct: 413 EDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIE 472

Query: 113 KYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKD 172
                L        + +RA I+  E    RL    E+ +FL  +  + + L      L  
Sbjct: 473 VLKESLTA------KEQRAAILQTEVDALRLRLE-EKESFLNKKTKQLQDLTEEKGTLAG 525

Query: 173 EARDLRQELAVRERQQEVTRK 193
           E RD++  L V+ER+  V +K
Sbjct: 526 EIRDMKDMLEVKERKINVLQK 546



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 15/142 (10%)

Query: 44  SRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQ 103
           +++LE +  AQL++  +R  D  ADN +   ++E L   LE          +  E D ++
Sbjct: 771 NQQLEKKKNAQLLEEVRRREDSMADNSQ-HLQIEELMNALEK---------TRQELDATK 820

Query: 104 TRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERN----AFLESELDE 159
            R    Q     +E   AN  +ER K+   + LE  ++ L  AI       A LE    +
Sbjct: 821 ARLASTQQSLAEKEAHLANLRIERRKQLEEI-LEMKQEALLAAISEKDANIALLELSASK 879

Query: 160 KESLLVSVQRLKDEARDLRQEL 181
           K+     V  LK E   L  +L
Sbjct: 880 KKKTQEEVMALKREKDRLVHQL 901


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,347,018
Number of Sequences: 37866
Number of extensions: 659798
Number of successful extensions: 8517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 362
Number of HSP's successfully gapped in prelim test: 765
Number of HSP's that attempted gapping in prelim test: 4542
Number of HSP's gapped (non-prelim): 3398
length of query: 345
length of database: 18,247,518
effective HSP length: 103
effective length of query: 242
effective length of database: 14,347,320
effective search space: 3472051440
effective search space used: 3472051440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press