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Search of human proteins with 13540600
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13540600 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform B [Homo sapiens]
(345 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan... 673 0.0
gi|71284108 nudE nuclear distribution gene E homolog (A. nidulan... 611 e-175
gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens] 339 2e-93
gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens] 339 2e-93
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 60 4e-09
gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [... 60 4e-09
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 60 4e-09
gi|224451082 cytospin A [Homo sapiens] 58 1e-08
gi|224451080 cytospin A [Homo sapiens] 58 1e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 57 3e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 57 3e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 57 3e-08
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 57 3e-08
gi|16262452 cingulin [Homo sapiens] 55 9e-08
gi|157743265 caspase recruitment domain family, member 11 [Homo ... 55 9e-08
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens] 54 2e-07
gi|169217489 PREDICTED: similar to phosphodiesterase 4D interact... 53 3e-07
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 53 3e-07
gi|32698688 citron [Homo sapiens] 52 6e-07
gi|148746195 trichohyalin [Homo sapiens] 52 8e-07
gi|119120918 coiled-coil domain containing 64 [Homo sapiens] 52 1e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 51 1e-06
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 51 1e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 51 2e-06
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 51 2e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 51 2e-06
gi|149363685 hypothetical protein LOC23379 [Homo sapiens] 50 2e-06
gi|109255239 centrosomal protein 63 isoform b [Homo sapiens] 50 2e-06
gi|22095367 centrosomal protein 63 isoform a [Homo sapiens] 50 2e-06
gi|34577114 cytomatrix protein p110 [Homo sapiens] 50 2e-06
>gi|13540600 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform B [Homo sapiens]
Length = 345
Score = 673 bits (1736), Expect = 0.0
Identities = 345/345 (100%), Positives = 345/345 (100%)
Query: 1 MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ 60
MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ
Sbjct: 1 MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ 60
Query: 61 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ
Sbjct: 61 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE
Sbjct: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
Query: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG 240
LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG
Sbjct: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG 240
Query: 241 TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG 300
TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG
Sbjct: 241 TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG 300
Query: 301 TKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV 345
TKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV
Sbjct: 301 TKFSRSGHTSFFDKGAVNGFDPAPPPPGLGSSRPSSAPGMLPLSV 345
>gi|71284108 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform A [Homo sapiens]
Length = 328
Score = 611 bits (1576), Expect = e-175
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ 60
MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ
Sbjct: 1 MDGEDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ 60
Query: 61 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ
Sbjct: 61 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE
Sbjct: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
Query: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG 240
LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG
Sbjct: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFG 240
Query: 241 TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG 300
TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG
Sbjct: 241 TSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNG 300
Query: 301 TKFSRSGHTSFFDKG 315
TKFSRSGHTSFFDKG
Sbjct: 301 TKFSRSGHTSFFDKG 315
>gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]
Length = 335
Score = 339 bits (870), Expect = 2e-93
Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%)
Query: 9 FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68
FSS +EE YWK+L++ YKQ + ++EL EFQEGSRE EAELE QL Q E RNRDL ++
Sbjct: 8 FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67
Query: 69 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA
Sbjct: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q
Sbjct: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186
Query: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243
E R PSS ++ E+ D+AVQA+ S+P+TP+ +G ++ +P + G G +P
Sbjct: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244
Query: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285
LTP+ARISALNIVGDLLRKVGALESKLA+CRN DQ+ ++
Sbjct: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286
>gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
Length = 335
Score = 339 bits (870), Expect = 2e-93
Identities = 181/282 (64%), Positives = 226/282 (80%), Gaps = 8/282 (2%)
Query: 9 FSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQAD 68
FSS +EE YWK+L++ YKQ + ++EL EFQEGSRE EAELE QL Q E RNRDL ++
Sbjct: 8 FSSEEEEANYWKDLAMTYKQRAENTQEELREFQEGSREYEAELETQLQQIETRNRDLLSE 67
Query: 69 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
N RL+ E+E +KEK E Q+++ Y+Q+S LEDDL+QT+AIK+QL KY+RELEQANDDLERA
Sbjct: 68 NNRLRMELETIKEKFEVQHSEGYRQISALEDDLAQTKAIKDQLQKYIRELEQANDDLERA 127
Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
KRATI+SLEDFEQRLNQAIERNAFLESELDEKE+LL SVQRLKDEARDLRQELAV+++ Q
Sbjct: 128 KRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDLRQELAVQQK-Q 186
Query: 189 EVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVG-KGTENTFPSPKAIPNGF----GTSP 243
E R PSS ++ E+ D+AVQA+ S+P+TP+ +G ++ +P + G G +P
Sbjct: 187 EKPRTPMPSS--VEAERTDTAVQATGSVPSTPIAHRGPSSSLNTPGSFRRGLDDSTGGTP 244
Query: 244 LTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKS 285
LTP+ARISALNIVGDLLRKVGALESKLA+CRN DQ+ ++
Sbjct: 245 LTPAARISALNIVGDLLRKVGALESKLASCRNLVYDQSPNRT 286
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 59.7 bits (143), Expect = 4e-09
Identities = 52/182 (28%), Positives = 95/182 (52%), Gaps = 17/182 (9%)
Query: 36 ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
+ V+F E + E E Q + + N++L+ Q+L+ E++ ++L A+ Y ++
Sbjct: 374 QCVQFVEAAAH---ESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR 430
Query: 96 VLEDD---LSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAF 152
E + L+ + + KEQL + REL Q D+ ++ A + LE QR++ ++
Sbjct: 431 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIH---DKAVA 487
Query: 153 LESELDEKESLLVSVQRLKDEARDLRQ-ELAVRERQQEVTR-KSAPSSPTLDCEKMDSAV 210
LE +DEK S L+++ ++LRQ LAVRER ++ R + SS + M+S +
Sbjct: 488 LERAIDEKFS------ALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLL 541
Query: 211 QA 212
+A
Sbjct: 542 RA 543
Score = 31.2 bits (69), Expect = 1.4
Identities = 39/186 (20%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 27 KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYE----------- 75
KQ + + + Q S AEL+ ++ Q E N+ LQ + YE
Sbjct: 220 KQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQ 279
Query: 76 ---VEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
++ LKE L+ + ++ + V+E ++E LH+ +L Q + +
Sbjct: 280 DGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ--SQLGQLHSSEGTSPAQQ 337
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVS----VQRLKDEARDLRQELAVRERQQ 188
V+L D + L + L+ + +KE L VQ ++ A + Q+ +
Sbjct: 338 QVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHN 397
Query: 189 EVTRKS 194
+ RK+
Sbjct: 398 QELRKA 403
>gi|50658071 phosphodiesterase 4D interacting protein isoform 5
[Homo sapiens]
Length = 1132
Score = 59.7 bits (143), Expect = 4e-09
Identities = 52/182 (28%), Positives = 95/182 (52%), Gaps = 17/182 (9%)
Query: 36 ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
+ V+F E + E E Q + + N++L+ Q+L+ E++ ++L A+ Y ++
Sbjct: 537 QCVQFVEAAAH---ESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR 593
Query: 96 VLEDD---LSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAF 152
E + L+ + + KEQL + REL Q D+ ++ A + LE QR++ ++
Sbjct: 594 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIH---DKAVA 650
Query: 153 LESELDEKESLLVSVQRLKDEARDLRQ-ELAVRERQQEVTR-KSAPSSPTLDCEKMDSAV 210
LE +DEK S L+++ ++LRQ LAVRER ++ R + SS + M+S +
Sbjct: 651 LERAIDEKFS------ALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLL 704
Query: 211 QA 212
+A
Sbjct: 705 RA 706
Score = 31.2 bits (69), Expect = 1.4
Identities = 39/186 (20%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 27 KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYE----------- 75
KQ + + + Q S AEL+ ++ Q E N+ LQ + YE
Sbjct: 383 KQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQ 442
Query: 76 ---VEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
++ LKE L+ + ++ + V+E ++E LH+ +L Q + +
Sbjct: 443 DGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ--SQLGQLHSSEGTSPAQQ 500
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVS----VQRLKDEARDLRQELAVRERQQ 188
V+L D + L + L+ + +KE L VQ ++ A + Q+ +
Sbjct: 501 QVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHN 560
Query: 189 EVTRKS 194
+ RK+
Sbjct: 561 QELRKA 566
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 59.7 bits (143), Expect = 4e-09
Identities = 52/182 (28%), Positives = 95/182 (52%), Gaps = 17/182 (9%)
Query: 36 ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
+ V+F E + E E Q + + N++L+ Q+L+ E++ ++L A+ Y ++
Sbjct: 374 QCVQFVEAAAH---ESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIR 430
Query: 96 VLEDD---LSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAF 152
E + L+ + + KEQL + REL Q D+ ++ A + LE QR++ ++
Sbjct: 431 TQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIH---DKAVA 487
Query: 153 LESELDEKESLLVSVQRLKDEARDLRQ-ELAVRERQQEVTR-KSAPSSPTLDCEKMDSAV 210
LE +DEK S L+++ ++LRQ LAVRER ++ R + SS + M+S +
Sbjct: 488 LERAIDEKFS------ALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLL 541
Query: 211 QA 212
+A
Sbjct: 542 RA 543
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/107 (25%), Positives = 47/107 (43%), Gaps = 7/107 (6%)
Query: 62 NRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQA 121
NR LQA + E E L S + LE +L + ++QL + +RE +Q
Sbjct: 1911 NRRLQAQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQE 1970
Query: 122 NDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ 168
+ +SL++ + RL + L+ + +EK+ L S+Q
Sbjct: 1971 VLHFREER----LSLQENDSRLQHKL---VLLQQQCEEKQQLFESLQ 2010
Score = 32.7 bits (73), Expect = 0.49
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Query: 17 AYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEV 76
A +S ++ Q + R+ L+ + +ELE ELE Q V+ +Q DL+ Q + +
Sbjct: 1916 AQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVERQQLLEDLREKQQEVLHFR 1975
Query: 77 EALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
E E+ +K V +L+ + + + E L ++ E + ++ +A
Sbjct: 1976 EERLSLQENDSRLQHKLV-LLQQQCEEKQQLFESLQSELQIYEALYGNSKKGLKA 2029
Score = 31.2 bits (69), Expect = 1.4
Identities = 39/186 (20%), Positives = 74/186 (39%), Gaps = 20/186 (10%)
Query: 27 KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYE----------- 75
KQ + + + Q S AEL+ ++ Q E N+ LQ + YE
Sbjct: 220 KQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQ 279
Query: 76 ---VEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
++ LKE L+ + ++ + V+E ++E LH+ +L Q + +
Sbjct: 280 DGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQ--SQLGQLHSSEGTSPAQQ 337
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVS----VQRLKDEARDLRQELAVRERQQ 188
V+L D + L + L+ + +KE L VQ ++ A + Q+ +
Sbjct: 338 QVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHN 397
Query: 189 EVTRKS 194
+ RK+
Sbjct: 398 QELRKA 403
>gi|224451082 cytospin A [Homo sapiens]
Length = 1117
Score = 57.8 bits (138), Expect = 1e-08
Identities = 60/267 (22%), Positives = 119/267 (44%), Gaps = 39/267 (14%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
SSL+E+ A+ + + + + + + DE FQE +++ +L L + + + +
Sbjct: 624 SSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETER 683
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE---------- 119
+K + L++++E A ++ D + + +++Q H RE++
Sbjct: 684 SDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREES 743
Query: 120 ----QANDDLERA-------KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ 168
Q DL+ A K + D ++RL++A E+N L EL+E +S +
Sbjct: 744 AEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEE 803
Query: 169 --RLKDEARDLRQELAVRERQQEVTRKSAPSS---PTLD--CEKMDSAVQ----ASLSLP 217
R+ + + ++LA + ++R+S+ SS PT+ + DSA Q A+ ++P
Sbjct: 804 RGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIP 863
Query: 218 ATPVGKGTENTFPSPKAIPNGFGTSPL 244
TP+ PSP P SP+
Sbjct: 864 RTPLS-------PSPMKTPPAAAVSPM 883
Score = 34.7 bits (78), Expect = 0.13
Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 28/179 (15%)
Query: 27 KQSFQEARDELVEFQEGSRELE----------AELEAQLVQAEQRNRDLQADNQRLKYEV 76
+Q +EA++ + +E S +E A L A L + + Q + RLK ++
Sbjct: 524 EQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQL 583
Query: 77 EALKEKLEHQYA-QSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ----ANDDLERAKRA 131
E K+K+ Y+ + S ++D L R KE+ L++ +D R + A
Sbjct: 584 ENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDA 643
Query: 132 TIVSLED----FEQRLNQAIE-RNAFLE---SELDEKES----LLVSVQRLKDEARDLR 178
I +ED F++ + IE N LE S+LDEKE+ + ++ L+DE R
Sbjct: 644 -IAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHR 701
>gi|224451080 cytospin A [Homo sapiens]
Length = 1117
Score = 57.8 bits (138), Expect = 1e-08
Identities = 60/267 (22%), Positives = 119/267 (44%), Gaps = 39/267 (14%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
SSL+E+ A+ + + + + + + DE FQE +++ +L L + + + +
Sbjct: 624 SSLQEDLAHTRNDANRLQDAIAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETER 683
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE---------- 119
+K + L++++E A ++ D + + +++Q H RE++
Sbjct: 684 SDMKETIFELEDEVEQHRAVKLHDNLIISDLENTVKKLQDQKHDMEREIKTLHRRLREES 743
Query: 120 ----QANDDLERA-------KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ 168
Q DL+ A K + D ++RL++A E+N L EL+E +S +
Sbjct: 744 AEWRQFQADLQTAVVIANDIKSEAQEEIGDLKRRLHEAQEKNEKLTKELEEIKSRKQEEE 803
Query: 169 --RLKDEARDLRQELAVRERQQEVTRKSAPSS---PTLD--CEKMDSAVQ----ASLSLP 217
R+ + + ++LA + ++R+S+ SS PT+ + DSA Q A+ ++P
Sbjct: 804 RGRVYNYMNAVERDLAALRQGMGLSRRSSTSSEPTPTVKTLIKSFDSASQVPNPAAAAIP 863
Query: 218 ATPVGKGTENTFPSPKAIPNGFGTSPL 244
TP+ PSP P SP+
Sbjct: 864 RTPLS-------PSPMKTPPAAAVSPM 883
Score = 34.7 bits (78), Expect = 0.13
Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 28/179 (15%)
Query: 27 KQSFQEARDELVEFQEGSRELE----------AELEAQLVQAEQRNRDLQADNQRLKYEV 76
+Q +EA++ + +E S +E A L A L + + Q + RLK ++
Sbjct: 524 EQDNKEAQEMIGALKERSHHMERIIESEQKGKAALAATLEEYKATVASDQIEMNRLKAQL 583
Query: 77 EALKEKLEHQYA-QSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ----ANDDLERAKRA 131
E K+K+ Y+ + S ++D L R KE+ L++ +D R + A
Sbjct: 584 ENEKQKVAELYSIHNSGDKSDIQDLLESVRLDKEKAETLASSLQEDLAHTRNDANRLQDA 643
Query: 132 TIVSLED----FEQRLNQAIE-RNAFLE---SELDEKES----LLVSVQRLKDEARDLR 178
I +ED F++ + IE N LE S+LDEKE+ + ++ L+DE R
Sbjct: 644 -IAKVEDEYRAFQEEAKKQIEDLNMTLEKLRSDLDEKETERSDMKETIFELEDEVEQHR 701
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 56.6 bits (135), Expect = 3e-08
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 11/202 (5%)
Query: 11 SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
+L EET + + +Q +A +EL E E + +A L+ E+ N DL + +
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1241
Query: 71 RL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRA-IKEQLHKYVRELEQANDDLE 126
L K EVE K+KLE Q + + S D + RA + +++HK E+E L
Sbjct: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCS----DGERARAELNDKVHKLQNEVESVTGMLN 1297
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
A+ I +D +Q + L+ E +K ++ +++L++E L+ +L +
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL---DE 1354
Query: 187 QQEVTRKSAPSSPTLDCEKMDS 208
+ E + TL+ + DS
Sbjct: 1355 EMEAKQNLERHISTLNIQLSDS 1376
Score = 51.6 bits (122), Expect = 1e-06
Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 9/184 (4%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQ 66
S L EE +E + + EA + V +ELE E+EA+L + E R + LQ
Sbjct: 883 SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 942
Query: 67 ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
A+ +++ ++ L+E+LE + A K L+ + A ++L + ++ N+ L
Sbjct: 943 AERKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLS 998
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ-RLKDEARDLRQELAVRE 185
+ ++ + D L + E+ L ++ ES++ ++ RLK E + RQEL +
Sbjct: 999 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK 1057
Query: 186 RQQE 189
R+ E
Sbjct: 1058 RKLE 1061
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 51/225 (22%)
Query: 20 KELSLKYK----QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK-- 73
K +S KY ++ EAR++ + +R LE LEA+ + E+ N+ L+A+ + L
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1519
Query: 74 --------YEVEALKEKLEHQYAQSYKQVSVLEDDLSQT--------------------- 104
+E+E K LE Q + Q+ LED+L T
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579
Query: 105 ------------RAIKEQLHKYVRELEQANDD---LERAKRATIVSLEDFEQRLNQAIER 149
R ++ QLH+Y ELE AK+ L+D E + + AI+
Sbjct: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639
Query: 150 NAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKS 194
+L + ++ + QR ++AR R E+ ++ E KS
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 11/202 (5%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK+E +EL ++ +A D F E +L+A++ +Q ++ +LQA R
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASD----FHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L E+ A K + + +S L++DL RA + + K R+L + + L+
Sbjct: 1099 LDDEI-AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEV 190
T+ S ++ + + L+ LDE+ S VQ ++ + +EL E+ ++
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT--EQLEQF 1215
Query: 191 TRKSA---PSSPTLDCEKMDSA 209
R A + TL+ E D A
Sbjct: 1216 KRAKANLDKNKQTLEKENADLA 1237
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 5/176 (2%)
Query: 14 EETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK 73
+ TA +EL K +Q + L E E+ + QA + + +R K
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 74 YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
++ K+ LE + A ++ VL + K++L V+EL+ D ERA+
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR---- 1275
Query: 134 VSLEDFEQRLNQAIERNAFLESELDEKE-SLLVSVQRLKDEARDLRQELAVRERQQ 188
L D +L +E + +E + K L V L + +D ++ L RQ+
Sbjct: 1276 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)
Query: 33 ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYK 92
+RDE+ + + + LEA L+Q ++ DL A +R + + + KE+L + A S
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQE---DLAA-AERARKQADLEKEELAEELASSLS 1722
Query: 93 QVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKR---------ATIVSLEDF 139
+ L+D+ + A ++E+L + +E +D + +A + AT S
Sbjct: 1723 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1782
Query: 140 EQRLNQAIER-NAFLESELDEKESLLVS-----VQRLKDEARDLRQELAVRERQQEVTRK 193
+ Q +ER N L S+L E E + S + L+ + L +++ R+++ K
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1842
Query: 194 S 194
S
Sbjct: 1843 S 1843
Score = 38.1 bits (87), Expect = 0.012
Identities = 49/214 (22%), Positives = 95/214 (44%), Gaps = 44/214 (20%)
Query: 4 EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQL-----VQA 58
++I + + EE A + K K Q+ D+LV + R+L + LE + + A
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 59 EQRNRDLQADNQRLKYEVEAL-KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
E++N + ++R + E EA KE A++ ++ +++L +T + L + +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAEMED 1515
Query: 118 LEQANDD-------LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-------- 162
L + DD LE++KRA +E+ ++++L+E E
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEE--------------MKTQLEELEDELQATEDA 1561
Query: 163 ---LLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
L V++Q LK + ++L R+ Q E R+
Sbjct: 1562 KLRLEVNMQALKGQ---FERDLQARDEQNEEKRR 1592
Score = 37.7 bits (86), Expect = 0.015
Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 32/185 (17%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADN 69
+E+ +L K++ E L + ++ +ELE +LE ++ DLQA
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER-- 127
LK ++ +E+L+ A+ L+D+++Q K K +RELE DL+
Sbjct: 1079 AELKMQLAKKEEELQAALAR-------LDDEIAQ----KNNALKKIRELEGHISDLQEDL 1127
Query: 128 -AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
++RA E ++ L + +E L++EL++ + Q L+ +R
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEA---LKTELEDTLDSTATQQELR------------AKR 1172
Query: 187 QQEVT 191
+QEVT
Sbjct: 1173 EQEVT 1177
Score = 37.4 bits (85), Expect = 0.020
Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 19/196 (9%)
Query: 8 DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAE----- 59
D L+E+ A + + +E +EL G L+ E LEA++ Q E
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747
Query: 60 -QRNRDLQADNQR-LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
Q N + +D R + E L +L + + + K S + Q + ++ +LH E
Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH----E 1803
Query: 118 LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
+E A ++ ++TI +LE +L + +E+ A + +SL ++LK+ +
Sbjct: 1804 MEGA---VKSKFKSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKLKEILLQV 1858
Query: 178 RQELAVRERQQEVTRK 193
E + E+ +E K
Sbjct: 1859 EDERKMAEQYKEQAEK 1874
Score = 37.0 bits (84), Expect = 0.026
Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 19/178 (10%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
L+EET +S K +Q +E R+ L + +L+ E+EA+ ++L+
Sbjct: 1324 LQEETRQKLNVSTKLRQ-LEEERNSLQD------QLDEEMEAK--------QNLERHIST 1368
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L ++ K+KL+ +A + V LE+ + + E L + E A D LE+ K
Sbjct: 1369 LNIQLSDSKKKLQ-DFAST---VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
L+D L+ + + LE + + + LL + + + D R R++E
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482
Score = 36.6 bits (83), Expect = 0.034
Identities = 22/102 (21%), Positives = 47/102 (46%)
Query: 86 QYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQ 145
Q + +++ ED+L +T+ +++ ++ELEQ + L K L+ + +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 146 AIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
A E L ++ E E +L ++ +E D Q+L ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947
Score = 36.6 bits (83), Expect = 0.034
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 33/173 (19%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE-----------AELEAQLV---- 56
L E A + + K + + Q+ + E + E+E A LEA++
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828
Query: 57 QAEQRNRDLQADNQRLKYEVEALKEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
Q EQ R+ QA + LK + + LKE L E + A+ YK+ + E ++ + +K QL
Sbjct: 1829 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--EKGNARVKQLKRQL 1886
Query: 112 HKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
+ E ++ N + + +R L++A E N + E++ +S L
Sbjct: 1887 EEAEEESQRINANRRKLQR-----------ELDEATESNEAMGREVNALKSKL 1928
Score = 36.2 bits (82), Expect = 0.044
Identities = 45/178 (25%), Positives = 86/178 (48%), Gaps = 34/178 (19%)
Query: 28 QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
+ +E + + QE +L++E A+ +AE++ RDL E+EALK +LE
Sbjct: 1111 KKIRELEGHISDLQE---DLDSERAARN-KAEKQKRDLGE-------ELEALKTELEDTL 1159
Query: 88 ----------AQSYKQVSVL-----EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
A+ ++V+VL E+ S ++E K+ + +E+ + LE+ KRA
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 133 IVSLEDFEQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 186
+L+ +Q L + NA L EL K+ + ++L+ + ++L+ + + ER
Sbjct: 1220 -ANLDKNKQTLE---KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1273
Score = 33.5 bits (75), Expect = 0.29
Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK W L K K Q R E E Q EL+ E Q +AE ++L+ + +
Sbjct: 827 LKLRNWQWWRLFTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQ-KAENELKELEQKHSQ 884
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L E L+E+L+ + + Y + + L+ A K++L + + E+E
Sbjct: 885 LTEEKNLLQEQLQAE-TELYAEAEEMRVRLA---AKKQELEEILHEME------------ 928
Query: 132 TIVSLEDFEQRLNQ-AIERNAFLESELDEKESL-LVSVQRLKDEARDLRQELAVRERQQE 189
LE+ E R Q ER + LD +E L R K + + E +++ + E
Sbjct: 929 --ARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986
Query: 190 V 190
+
Sbjct: 987 I 987
Score = 33.5 bits (75), Expect = 0.29
Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 9/117 (7%)
Query: 68 DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLE 126
D Q L E K + + Q ++ + L+D L + K+ L +++ L Q +D +
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 127 RAK--RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
+ + +T+ +LE+ ++R + IE L + +EK + +++ K+ L+QEL
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIEN---LTQQYEEKAAAYDKLEKTKNR---LQQEL 1429
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 56.6 bits (135), Expect = 3e-08
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 11/202 (5%)
Query: 11 SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
+L EET + + +Q +A +EL E E + +A L+ E+ N DL + +
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1248
Query: 71 RL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRA-IKEQLHKYVRELEQANDDLE 126
L K EVE K+KLE Q + + S D + RA + +++HK E+E L
Sbjct: 1249 VLGQAKQEVEHKKKKLEAQVQELQSKCS----DGERARAELNDKVHKLQNEVESVTGMLN 1304
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
A+ I +D +Q + L+ E +K ++ +++L++E L+ +L +
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL---DE 1361
Query: 187 QQEVTRKSAPSSPTLDCEKMDS 208
+ E + TL+ + DS
Sbjct: 1362 EMEAKQNLERHISTLNIQLSDS 1383
Score = 51.6 bits (122), Expect = 1e-06
Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 9/184 (4%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQ 66
S L EE +E + + EA + V +ELE E+EA+L + E R + LQ
Sbjct: 890 SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 949
Query: 67 ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
A+ +++ ++ L+E+LE + A K L+ + A ++L + ++ N+ L
Sbjct: 950 AERKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLS 1005
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ-RLKDEARDLRQELAVRE 185
+ ++ + D L + E+ L ++ ES++ ++ RLK E + RQEL +
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK 1064
Query: 186 RQQE 189
R+ E
Sbjct: 1065 RKLE 1068
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 51/225 (22%)
Query: 20 KELSLKYK----QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK-- 73
K +S KY ++ EAR++ + +R LE LEA+ + E+ N+ L+A+ + L
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1526
Query: 74 --------YEVEALKEKLEHQYAQSYKQVSVLEDDLSQT--------------------- 104
+E+E K LE Q + Q+ LED+L T
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1586
Query: 105 ------------RAIKEQLHKYVRELEQANDD---LERAKRATIVSLEDFEQRLNQAIER 149
R ++ QLH+Y ELE AK+ L+D E + + AI+
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646
Query: 150 NAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKS 194
+L + ++ + QR ++AR R E+ ++ E KS
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 11/202 (5%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK+E +EL ++ +A D F E +L+A++ +Q ++ +LQA R
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASD----FHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L E+ A K + + +S L++DL RA + + K R+L + + L+
Sbjct: 1106 LDDEI-AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEV 190
T+ S ++ + + L+ LDE+ S VQ ++ + +EL E+ ++
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT--EQLEQF 1222
Query: 191 TRKSA---PSSPTLDCEKMDSA 209
R A + TL+ E D A
Sbjct: 1223 KRAKANLDKNKQTLEKENADLA 1244
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 5/176 (2%)
Query: 14 EETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK 73
+ TA +EL K +Q + L E E+ + QA + + +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 74 YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
++ K+ LE + A ++ VL + K++L V+EL+ D ERA+
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR---- 1282
Query: 134 VSLEDFEQRLNQAIERNAFLESELDEKE-SLLVSVQRLKDEARDLRQELAVRERQQ 188
L D +L +E + +E + K L V L + +D ++ L RQ+
Sbjct: 1283 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)
Query: 33 ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYK 92
+RDE+ + + + LEA L+Q ++ DL A +R + + + KE+L + A S
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQE---DLAA-AERARKQADLEKEELAEELASSLS 1729
Query: 93 QVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKR---------ATIVSLEDF 139
+ L+D+ + A ++E+L + +E +D + +A + AT S
Sbjct: 1730 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1789
Query: 140 EQRLNQAIER-NAFLESELDEKESLLVS-----VQRLKDEARDLRQELAVRERQQEVTRK 193
+ Q +ER N L S+L E E + S + L+ + L +++ R+++ K
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1849
Query: 194 S 194
S
Sbjct: 1850 S 1850
Score = 38.1 bits (87), Expect = 0.012
Identities = 49/214 (22%), Positives = 95/214 (44%), Gaps = 44/214 (20%)
Query: 4 EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQL-----VQA 58
++I + + EE A + K K Q+ D+LV + R+L + LE + + A
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 59 EQRNRDLQADNQRLKYEVEAL-KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
E++N + ++R + E EA KE A++ ++ +++L +T + L + +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAEMED 1522
Query: 118 LEQANDD-------LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-------- 162
L + DD LE++KRA +E+ ++++L+E E
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEE--------------MKTQLEELEDELQATEDA 1568
Query: 163 ---LLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
L V++Q LK + ++L R+ Q E R+
Sbjct: 1569 KLRLEVNMQALKGQ---FERDLQARDEQNEEKRR 1599
Score = 37.7 bits (86), Expect = 0.015
Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 32/185 (17%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADN 69
+E+ +L K++ E L + ++ +ELE +LE ++ DLQA
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER-- 127
LK ++ +E+L+ A+ L+D+++Q K K +RELE DL+
Sbjct: 1086 AELKMQLAKKEEELQAALAR-------LDDEIAQ----KNNALKKIRELEGHISDLQEDL 1134
Query: 128 -AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
++RA E ++ L + +E L++EL++ + Q L+ +R
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEA---LKTELEDTLDSTATQQELR------------AKR 1179
Query: 187 QQEVT 191
+QEVT
Sbjct: 1180 EQEVT 1184
Score = 37.4 bits (85), Expect = 0.020
Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 19/196 (9%)
Query: 8 DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAE----- 59
D L+E+ A + + +E +EL G L+ E LEA++ Q E
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754
Query: 60 -QRNRDLQADNQR-LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
Q N + +D R + E L +L + + + K S + Q + ++ +LH E
Sbjct: 1755 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH----E 1810
Query: 118 LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
+E A ++ ++TI +LE +L + +E+ A + +SL ++LK+ +
Sbjct: 1811 MEGA---VKSKFKSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKLKEILLQV 1865
Query: 178 RQELAVRERQQEVTRK 193
E + E+ +E K
Sbjct: 1866 EDERKMAEQYKEQAEK 1881
Score = 37.0 bits (84), Expect = 0.026
Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 19/178 (10%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
L+EET +S K +Q +E R+ L + +L+ E+EA+ ++L+
Sbjct: 1331 LQEETRQKLNVSTKLRQ-LEEERNSLQD------QLDEEMEAK--------QNLERHIST 1375
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L ++ K+KL+ +A + V LE+ + + E L + E A D LE+ K
Sbjct: 1376 LNIQLSDSKKKLQ-DFAST---VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
L+D L+ + + LE + + + LL + + + D R R++E
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489
Score = 36.6 bits (83), Expect = 0.034
Identities = 22/102 (21%), Positives = 47/102 (46%)
Query: 86 QYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQ 145
Q + +++ ED+L +T+ +++ ++ELEQ + L K L+ + +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 146 AIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
A E L ++ E E +L ++ +E D Q+L ++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954
Score = 36.6 bits (83), Expect = 0.034
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 33/173 (19%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE-----------AELEAQLV---- 56
L E A + + K + + Q+ + E + E+E A LEA++
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835
Query: 57 QAEQRNRDLQADNQRLKYEVEALKEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
Q EQ R+ QA + LK + + LKE L E + A+ YK+ + E ++ + +K QL
Sbjct: 1836 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--EKGNARVKQLKRQL 1893
Query: 112 HKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
+ E ++ N + + +R L++A E N + E++ +S L
Sbjct: 1894 EEAEEESQRINANRRKLQR-----------ELDEATESNEAMGREVNALKSKL 1935
Score = 36.2 bits (82), Expect = 0.044
Identities = 45/178 (25%), Positives = 86/178 (48%), Gaps = 34/178 (19%)
Query: 28 QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
+ +E + + QE +L++E A+ +AE++ RDL E+EALK +LE
Sbjct: 1118 KKIRELEGHISDLQE---DLDSERAARN-KAEKQKRDLGE-------ELEALKTELEDTL 1166
Query: 88 ----------AQSYKQVSVL-----EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
A+ ++V+VL E+ S ++E K+ + +E+ + LE+ KRA
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 133 IVSLEDFEQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 186
+L+ +Q L + NA L EL K+ + ++L+ + ++L+ + + ER
Sbjct: 1227 -ANLDKNKQTLE---KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1280
Score = 33.5 bits (75), Expect = 0.29
Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK W L K K Q R E E Q EL+ E Q +AE ++L+ + +
Sbjct: 834 LKLRNWQWWRLFTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQ-KAENELKELEQKHSQ 891
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L E L+E+L+ + + Y + + L+ A K++L + + E+E
Sbjct: 892 LTEEKNLLQEQLQAE-TELYAEAEEMRVRLA---AKKQELEEILHEME------------ 935
Query: 132 TIVSLEDFEQRLNQ-AIERNAFLESELDEKESL-LVSVQRLKDEARDLRQELAVRERQQE 189
LE+ E R Q ER + LD +E L R K + + E +++ + E
Sbjct: 936 --ARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993
Query: 190 V 190
+
Sbjct: 994 I 994
Score = 33.5 bits (75), Expect = 0.29
Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 9/117 (7%)
Query: 68 DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLE 126
D Q L E K + + Q ++ + L+D L + K+ L +++ L Q +D +
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 127 RAK--RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
+ + +T+ +LE+ ++R + IE L + +EK + +++ K+ L+QEL
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIEN---LTQQYEEKAAAYDKLEKTKNR---LQQEL 1436
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 56.6 bits (135), Expect = 3e-08
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 11/202 (5%)
Query: 11 SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
+L EET + + +Q +A +EL E E + +A L+ E+ N DL + +
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1248
Query: 71 RL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRA-IKEQLHKYVRELEQANDDLE 126
L K EVE K+KLE Q + + S D + RA + +++HK E+E L
Sbjct: 1249 VLGQAKQEVEHKKKKLEAQVQELQSKCS----DGERARAELNDKVHKLQNEVESVTGMLN 1304
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
A+ I +D +Q + L+ E +K ++ +++L++E L+ +L +
Sbjct: 1305 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL---DE 1361
Query: 187 QQEVTRKSAPSSPTLDCEKMDS 208
+ E + TL+ + DS
Sbjct: 1362 EMEAKQNLERHISTLNIQLSDS 1383
Score = 51.6 bits (122), Expect = 1e-06
Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 9/184 (4%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQ 66
S L EE +E + + EA + V +ELE E+EA+L + E R + LQ
Sbjct: 890 SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 949
Query: 67 ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
A+ +++ ++ L+E+LE + A K L+ + A ++L + ++ N+ L
Sbjct: 950 AERKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLS 1005
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ-RLKDEARDLRQELAVRE 185
+ ++ + D L + E+ L ++ ES++ ++ RLK E + RQEL +
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK 1064
Query: 186 RQQE 189
R+ E
Sbjct: 1065 RKLE 1068
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 51/225 (22%)
Query: 20 KELSLKYK----QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK-- 73
K +S KY ++ EAR++ + +R LE LEA+ + E+ N+ L+A+ + L
Sbjct: 1468 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1526
Query: 74 --------YEVEALKEKLEHQYAQSYKQVSVLEDDLSQT--------------------- 104
+E+E K LE Q + Q+ LED+L T
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1586
Query: 105 ------------RAIKEQLHKYVRELEQANDD---LERAKRATIVSLEDFEQRLNQAIER 149
R ++ QLH+Y ELE AK+ L+D E + + AI+
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646
Query: 150 NAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKS 194
+L + ++ + QR ++AR R E+ ++ E KS
Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1691
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 11/202 (5%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK+E +EL ++ +A D F E +L+A++ +Q ++ +LQA R
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASD----FHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L E+ A K + + +S L++DL RA + + K R+L + + L+
Sbjct: 1106 LDDEI-AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1164
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEV 190
T+ S ++ + + L+ LDE+ S VQ ++ + +EL E+ ++
Sbjct: 1165 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT--EQLEQF 1222
Query: 191 TRKSA---PSSPTLDCEKMDSA 209
R A + TL+ E D A
Sbjct: 1223 KRAKANLDKNKQTLEKENADLA 1244
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 5/176 (2%)
Query: 14 EETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK 73
+ TA +EL K +Q + L E E+ + QA + + +R K
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 74 YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
++ K+ LE + A ++ VL + K++L V+EL+ D ERA+
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR---- 1282
Query: 134 VSLEDFEQRLNQAIERNAFLESELDEKE-SLLVSVQRLKDEARDLRQELAVRERQQ 188
L D +L +E + +E + K L V L + +D ++ L RQ+
Sbjct: 1283 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)
Query: 33 ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYK 92
+RDE+ + + + LEA L+Q ++ DL A +R + + + KE+L + A S
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQE---DLAA-AERARKQADLEKEELAEELASSLS 1729
Query: 93 QVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKR---------ATIVSLEDF 139
+ L+D+ + A ++E+L + +E +D + +A + AT S
Sbjct: 1730 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1789
Query: 140 EQRLNQAIER-NAFLESELDEKESLLVS-----VQRLKDEARDLRQELAVRERQQEVTRK 193
+ Q +ER N L S+L E E + S + L+ + L +++ R+++ K
Sbjct: 1790 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1849
Query: 194 S 194
S
Sbjct: 1850 S 1850
Score = 38.1 bits (87), Expect = 0.012
Identities = 49/214 (22%), Positives = 95/214 (44%), Gaps = 44/214 (20%)
Query: 4 EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQL-----VQA 58
++I + + EE A + K K Q+ D+LV + R+L + LE + + A
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 59 EQRNRDLQADNQRLKYEVEAL-KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
E++N + ++R + E EA KE A++ ++ +++L +T + L + +
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAEMED 1522
Query: 118 LEQANDD-------LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-------- 162
L + DD LE++KRA +E+ ++++L+E E
Sbjct: 1523 LVSSKDDVGKNVHELEKSKRALETQMEE--------------MKTQLEELEDELQATEDA 1568
Query: 163 ---LLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
L V++Q LK + ++L R+ Q E R+
Sbjct: 1569 KLRLEVNMQALKGQ---FERDLQARDEQNEEKRR 1599
Score = 37.7 bits (86), Expect = 0.015
Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 32/185 (17%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADN 69
+E+ +L K++ E L + ++ +ELE +LE ++ DLQA
Sbjct: 1026 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1085
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER-- 127
LK ++ +E+L+ A+ L+D+++Q K K +RELE DL+
Sbjct: 1086 AELKMQLAKKEEELQAALAR-------LDDEIAQ----KNNALKKIRELEGHISDLQEDL 1134
Query: 128 -AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
++RA E ++ L + +E L++EL++ + Q L+ +R
Sbjct: 1135 DSERAARNKAEKQKRDLGEELEA---LKTELEDTLDSTATQQELR------------AKR 1179
Query: 187 QQEVT 191
+QEVT
Sbjct: 1180 EQEVT 1184
Score = 37.4 bits (85), Expect = 0.020
Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 19/196 (9%)
Query: 8 DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAE----- 59
D L+E+ A + + +E +EL G L+ E LEA++ Q E
Sbjct: 1695 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754
Query: 60 -QRNRDLQADNQR-LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
Q N + +D R + E L +L + + + K S + Q + ++ +LH E
Sbjct: 1755 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH----E 1810
Query: 118 LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
+E A ++ ++TI +LE +L + +E+ A + +SL ++LK+ +
Sbjct: 1811 MEGA---VKSKFKSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKLKEILLQV 1865
Query: 178 RQELAVRERQQEVTRK 193
E + E+ +E K
Sbjct: 1866 EDERKMAEQYKEQAEK 1881
Score = 37.0 bits (84), Expect = 0.026
Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 19/178 (10%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
L+EET +S K +Q +E R+ L + +L+ E+EA+ ++L+
Sbjct: 1331 LQEETRQKLNVSTKLRQ-LEEERNSLQD------QLDEEMEAK--------QNLERHIST 1375
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L ++ K+KL+ +A + V LE+ + + E L + E A D LE+ K
Sbjct: 1376 LNIQLSDSKKKLQ-DFAST---VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
L+D L+ + + LE + + + LL + + + D R R++E
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1489
Score = 36.6 bits (83), Expect = 0.034
Identities = 22/102 (21%), Positives = 47/102 (46%)
Query: 86 QYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQ 145
Q + +++ ED+L +T+ +++ ++ELEQ + L K L+ + +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 146 AIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
A E L ++ E E +L ++ +E D Q+L ++
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 954
Score = 36.6 bits (83), Expect = 0.034
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 33/173 (19%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE-----------AELEAQLV---- 56
L E A + + K + + Q+ + E + E+E A LEA++
Sbjct: 1776 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1835
Query: 57 QAEQRNRDLQADNQRLKYEVEALKEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
Q EQ R+ QA + LK + + LKE L E + A+ YK+ + E ++ + +K QL
Sbjct: 1836 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--EKGNARVKQLKRQL 1893
Query: 112 HKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
+ E ++ N + + +R L++A E N + E++ +S L
Sbjct: 1894 EEAEEESQRINANRRKLQR-----------ELDEATESNEAMGREVNALKSKL 1935
Score = 36.2 bits (82), Expect = 0.044
Identities = 45/178 (25%), Positives = 86/178 (48%), Gaps = 34/178 (19%)
Query: 28 QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
+ +E + + QE +L++E A+ +AE++ RDL E+EALK +LE
Sbjct: 1118 KKIRELEGHISDLQE---DLDSERAARN-KAEKQKRDLGE-------ELEALKTELEDTL 1166
Query: 88 ----------AQSYKQVSVL-----EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
A+ ++V+VL E+ S ++E K+ + +E+ + LE+ KRA
Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226
Query: 133 IVSLEDFEQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 186
+L+ +Q L + NA L EL K+ + ++L+ + ++L+ + + ER
Sbjct: 1227 -ANLDKNKQTLE---KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1280
Score = 33.5 bits (75), Expect = 0.29
Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK W L K K Q R E E Q EL+ E Q +AE ++L+ + +
Sbjct: 834 LKLRNWQWWRLFTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQ-KAENELKELEQKHSQ 891
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L E L+E+L+ + + Y + + L+ A K++L + + E+E
Sbjct: 892 LTEEKNLLQEQLQAE-TELYAEAEEMRVRLA---AKKQELEEILHEME------------ 935
Query: 132 TIVSLEDFEQRLNQ-AIERNAFLESELDEKESL-LVSVQRLKDEARDLRQELAVRERQQE 189
LE+ E R Q ER + LD +E L R K + + E +++ + E
Sbjct: 936 --ARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 993
Query: 190 V 190
+
Sbjct: 994 I 994
Score = 33.5 bits (75), Expect = 0.29
Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 9/117 (7%)
Query: 68 DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLE 126
D Q L E K + + Q ++ + L+D L + K+ L +++ L Q +D +
Sbjct: 1326 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 127 RAK--RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
+ + +T+ +LE+ ++R + IE L + +EK + +++ K+ L+QEL
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIEN---LTQQYEEKAAAYDKLEKTKNR---LQQEL 1436
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 56.6 bits (135), Expect = 3e-08
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 11/202 (5%)
Query: 11 SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
+L EET + + +Q +A +EL E E + +A L+ E+ N DL + +
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1241
Query: 71 RL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRA-IKEQLHKYVRELEQANDDLE 126
L K EVE K+KLE Q + + S D + RA + +++HK E+E L
Sbjct: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCS----DGERARAELNDKVHKLQNEVESVTGMLN 1297
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
A+ I +D +Q + L+ E +K ++ +++L++E L+ +L +
Sbjct: 1298 EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQL---DE 1354
Query: 187 QQEVTRKSAPSSPTLDCEKMDS 208
+ E + TL+ + DS
Sbjct: 1355 EMEAKQNLERHISTLNIQLSDS 1376
Score = 51.6 bits (122), Expect = 1e-06
Identities = 47/184 (25%), Positives = 88/184 (47%), Gaps = 9/184 (4%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQ 66
S L EE +E + + EA + V +ELE E+EA+L + E R + LQ
Sbjct: 883 SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 942
Query: 67 ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
A+ +++ ++ L+E+LE + A K L+ + A ++L + ++ N+ L
Sbjct: 943 AERKKMAQQMLDLEEQLEEEEAARQK----LQLEKVTAEAKIKKLEDEILVMDDQNNKLS 998
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ-RLKDEARDLRQELAVRE 185
+ ++ + D L + E+ L ++ ES++ ++ RLK E + RQEL +
Sbjct: 999 KERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKS-RQELEKLK 1057
Query: 186 RQQE 189
R+ E
Sbjct: 1058 RKLE 1061
Score = 47.0 bits (110), Expect = 3e-05
Identities = 55/225 (24%), Positives = 92/225 (40%), Gaps = 51/225 (22%)
Query: 20 KELSLKYK----QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK-- 73
K +S KY ++ EAR++ + +R LE LEA+ + E+ N+ L+A+ + L
Sbjct: 1461 KNISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSS 1519
Query: 74 --------YEVEALKEKLEHQYAQSYKQVSVLEDDLSQT--------------------- 104
+E+E K LE Q + Q+ LED+L T
Sbjct: 1520 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1579
Query: 105 ------------RAIKEQLHKYVRELEQANDD---LERAKRATIVSLEDFEQRLNQAIER 149
R ++ QLH+Y ELE AK+ L+D E + + AI+
Sbjct: 1580 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1639
Query: 150 NAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKS 194
+L + ++ + QR ++AR R E+ ++ E KS
Sbjct: 1640 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684
Score = 42.4 bits (98), Expect = 6e-04
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 11/202 (5%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK+E +EL ++ +A D F E +L+A++ +Q ++ +LQA R
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASD----FHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L E+ A K + + +S L++DL RA + + K R+L + + L+
Sbjct: 1099 LDDEI-AQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELED 1157
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEV 190
T+ S ++ + + L+ LDE+ S VQ ++ + +EL E+ ++
Sbjct: 1158 TLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELT--EQLEQF 1215
Query: 191 TRKSA---PSSPTLDCEKMDSA 209
R A + TL+ E D A
Sbjct: 1216 KRAKANLDKNKQTLEKENADLA 1237
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/176 (23%), Positives = 72/176 (40%), Gaps = 5/176 (2%)
Query: 14 EETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLK 73
+ TA +EL K +Q + L E E+ + QA + + +R K
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 74 YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
++ K+ LE + A ++ VL + K++L V+EL+ D ERA+
Sbjct: 1220 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERAR---- 1275
Query: 134 VSLEDFEQRLNQAIERNAFLESELDEKE-SLLVSVQRLKDEARDLRQELAVRERQQ 188
L D +L +E + +E + K L V L + +D ++ L RQ+
Sbjct: 1276 AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/181 (23%), Positives = 83/181 (45%), Gaps = 23/181 (12%)
Query: 33 ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYK 92
+RDE+ + + + LEA L+Q ++ DL A +R + + + KE+L + A S
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQE---DLAA-AERARKQADLEKEELAEELASSLS 1722
Query: 93 QVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKR---------ATIVSLEDF 139
+ L+D+ + A ++E+L + +E +D + +A + AT S
Sbjct: 1723 GRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQK 1782
Query: 140 EQRLNQAIER-NAFLESELDEKESLLVS-----VQRLKDEARDLRQELAVRERQQEVTRK 193
+ Q +ER N L S+L E E + S + L+ + L +++ R+++ K
Sbjct: 1783 NESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATK 1842
Query: 194 S 194
S
Sbjct: 1843 S 1843
Score = 38.1 bits (87), Expect = 0.012
Identities = 49/214 (22%), Positives = 95/214 (44%), Gaps = 44/214 (20%)
Query: 4 EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQL-----VQA 58
++I + + EE A + K K Q+ D+LV + R+L + LE + + A
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 59 EQRNRDLQADNQRLKYEVEAL-KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
E++N + ++R + E EA KE A++ ++ +++L +T + L + +
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN---KMLKAEMED 1515
Query: 118 LEQANDD-------LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-------- 162
L + DD LE++KRA +E+ ++++L+E E
Sbjct: 1516 LVSSKDDVGKNVHELEKSKRALETQMEE--------------MKTQLEELEDELQATEDA 1561
Query: 163 ---LLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
L V++Q LK + ++L R+ Q E R+
Sbjct: 1562 KLRLEVNMQALKGQ---FERDLQARDEQNEEKRR 1592
Score = 37.7 bits (86), Expect = 0.015
Identities = 45/185 (24%), Positives = 83/185 (44%), Gaps = 32/185 (17%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADN 69
+E+ +L K++ E L + ++ +ELE +LE ++ DLQA
Sbjct: 1019 EEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQI 1078
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER-- 127
LK ++ +E+L+ A+ L+D+++Q K K +RELE DL+
Sbjct: 1079 AELKMQLAKKEEELQAALAR-------LDDEIAQ----KNNALKKIRELEGHISDLQEDL 1127
Query: 128 -AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRER 186
++RA E ++ L + +E L++EL++ + Q L+ +R
Sbjct: 1128 DSERAARNKAEKQKRDLGEELEA---LKTELEDTLDSTATQQELR------------AKR 1172
Query: 187 QQEVT 191
+QEVT
Sbjct: 1173 EQEVT 1177
Score = 37.4 bits (85), Expect = 0.020
Identities = 45/196 (22%), Positives = 85/196 (43%), Gaps = 19/196 (9%)
Query: 8 DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAE----- 59
D L+E+ A + + +E +EL G L+ E LEA++ Q E
Sbjct: 1688 DLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747
Query: 60 -QRNRDLQADNQR-LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
Q N + +D R + E L +L + + + K S + Q + ++ +LH E
Sbjct: 1748 EQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLH----E 1803
Query: 118 LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
+E A ++ ++TI +LE +L + +E+ A + +SL ++LK+ +
Sbjct: 1804 MEGA---VKSKFKSTIAALEAKIAQLEEQVEQEA--REKQAATKSLKQKDKKLKEILLQV 1858
Query: 178 RQELAVRERQQEVTRK 193
E + E+ +E K
Sbjct: 1859 EDERKMAEQYKEQAEK 1874
Score = 37.0 bits (84), Expect = 0.026
Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 19/178 (10%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
L+EET +S K +Q +E R+ L + +L+ E+EA+ ++L+
Sbjct: 1324 LQEETRQKLNVSTKLRQ-LEEERNSLQD------QLDEEMEAK--------QNLERHIST 1368
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L ++ K+KL+ +A + V LE+ + + E L + E A D LE+ K
Sbjct: 1369 LNIQLSDSKKKLQ-DFAST---VEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
L+D L+ + + LE + + + LL + + + D R R++E
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKE 1482
Score = 36.6 bits (83), Expect = 0.034
Identities = 22/102 (21%), Positives = 47/102 (46%)
Query: 86 QYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQ 145
Q + +++ ED+L +T+ +++ ++ELEQ + L K L+ + +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 146 AIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
A E L ++ E E +L ++ +E D Q+L ++
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKK 947
Score = 36.6 bits (83), Expect = 0.034
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 33/173 (19%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE-----------AELEAQLV---- 56
L E A + + K + + Q+ + E + E+E A LEA++
Sbjct: 1769 LSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEE 1828
Query: 57 QAEQRNRDLQADNQRLKYEVEALKEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQL 111
Q EQ R+ QA + LK + + LKE L E + A+ YK+ + E ++ + +K QL
Sbjct: 1829 QVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQA--EKGNARVKQLKRQL 1886
Query: 112 HKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
+ E ++ N + + +R L++A E N + E++ +S L
Sbjct: 1887 EEAEEESQRINANRRKLQR-----------ELDEATESNEAMGREVNALKSKL 1928
Score = 36.2 bits (82), Expect = 0.044
Identities = 45/178 (25%), Positives = 86/178 (48%), Gaps = 34/178 (19%)
Query: 28 QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
+ +E + + QE +L++E A+ +AE++ RDL E+EALK +LE
Sbjct: 1111 KKIRELEGHISDLQE---DLDSERAARN-KAEKQKRDLGE-------ELEALKTELEDTL 1159
Query: 88 ----------AQSYKQVSVL-----EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
A+ ++V+VL E+ S ++E K+ + +E+ + LE+ KRA
Sbjct: 1160 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1219
Query: 133 IVSLEDFEQRLNQAIERNAFLESEL----DEKESLLVSVQRLKDEARDLRQELAVRER 186
+L+ +Q L + NA L EL K+ + ++L+ + ++L+ + + ER
Sbjct: 1220 -ANLDKNKQTLE---KENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGER 1273
Score = 33.5 bits (75), Expect = 0.29
Identities = 45/181 (24%), Positives = 75/181 (41%), Gaps = 22/181 (12%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK W L K K Q R E E Q EL+ E Q +AE ++L+ + +
Sbjct: 827 LKLRNWQWWRLFTKVKPLLQVTRQE-EEMQAKEDELQKTKERQQ-KAENELKELEQKHSQ 884
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
L E L+E+L+ + + Y + + L+ A K++L + + E+E
Sbjct: 885 LTEEKNLLQEQLQAE-TELYAEAEEMRVRLA---AKKQELEEILHEME------------ 928
Query: 132 TIVSLEDFEQRLNQ-AIERNAFLESELDEKESL-LVSVQRLKDEARDLRQELAVRERQQE 189
LE+ E R Q ER + LD +E L R K + + E +++ + E
Sbjct: 929 --ARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986
Query: 190 V 190
+
Sbjct: 987 I 987
Score = 33.5 bits (75), Expect = 0.29
Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 9/117 (7%)
Query: 68 DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLE 126
D Q L E K + + Q ++ + L+D L + K+ L +++ L Q +D +
Sbjct: 1319 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 127 RAK--RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
+ + +T+ +LE+ ++R + IE L + +EK + +++ K+ L+QEL
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIEN---LTQQYEEKAAAYDKLEKTKNR---LQQEL 1429
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 55.1 bits (131), Expect = 9e-08
Identities = 49/222 (22%), Positives = 94/222 (42%), Gaps = 43/222 (19%)
Query: 8 DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAEL--EAQLVQAEQRNRDL 65
+ EET +W+ + K K+ + + EL++ + E+E EL + +++Q E
Sbjct: 560 ELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQARA 619
Query: 66 QADNQRLKYEVEALKEKL---------------------EHQYAQSYKQVSVLEDDLSQT 104
A + R +VE LK++L H+ + KQ++VL + +
Sbjct: 620 SAGDTR---QVEVLKKELLRTQEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRG 676
Query: 105 RAIKEQLHKYVRELEQANDDLERAKRATIV-----------------SLEDFEQRLNQAI 147
R ++EQ + + L+Q D E A +A +V +L + ++ ++
Sbjct: 677 RELEEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFR 736
Query: 148 ERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
R LE +L E L+ + ++ RD Q L ++Q E
Sbjct: 737 RRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLE 778
Score = 48.9 bits (115), Expect = 7e-06
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 1/166 (0%)
Query: 28 QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQY 87
Q + + +L E S+E E L A E R + Q RL E + L LE +
Sbjct: 768 QRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEG 827
Query: 88 AQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAI 147
Q + Q R + + + +ELE+ +D ++A + LED++++ + +
Sbjct: 828 KQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREV 887
Query: 148 -ERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTR 192
+ + E E + RL+DE + LRQ L + +++ R
Sbjct: 888 ADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTAR 933
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/184 (25%), Positives = 87/184 (47%), Gaps = 32/184 (17%)
Query: 27 KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQ 86
KQ+ Q+ + +L +++E +R A+ + Q RL+ E++ L++ L
Sbjct: 866 KQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAEKTSGGLSRLQDEIQRLRQAL--- 922
Query: 87 YAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQA 146
Q S E D + R KE L + ++ LEQ ++ +R++ L+ E+++++
Sbjct: 923 ------QASQAERDTA--RLDKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSR- 973
Query: 147 IERNAFLESELDEK----ESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLD 202
LE+ELDE+ E L V R +D+ LR EL ++ER + L+
Sbjct: 974 ------LETELDEEKNTVELLTDRVNRGRDQVDQLRTEL-MQERS---------ARQDLE 1017
Query: 203 CEKM 206
C+K+
Sbjct: 1018 CDKI 1021
Score = 42.7 bits (99), Expect = 5e-04
Identities = 47/188 (25%), Positives = 85/188 (45%), Gaps = 26/188 (13%)
Query: 11 SLKEETAYWKELSLKYKQSFQEARDELVEF--QEGSRELEAELEAQLVQAEQRNRDLQAD 68
+LKEE A +RD+ VE Q+ R+ E +L + A Q + L+A+
Sbjct: 503 ALKEEVA---------------SRDQEVEHVRQQYQRDTE-QLRRSMQDATQDHAVLEAE 546
Query: 69 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
Q++ V L+ +LE ++ S+ + + RA K++L + E E+ ++L
Sbjct: 547 RQKMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGE- 605
Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKD-EARDLRQELAVRERQ 187
+E ++ L QA K+ LL + + LK+ +A QE+A R R
Sbjct: 606 ------KIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQSQEVAGRHRD 659
Query: 188 QEVTRKSA 195
+E+ ++ A
Sbjct: 660 RELEKQLA 667
Score = 42.7 bits (99), Expect = 5e-04
Identities = 50/204 (24%), Positives = 89/204 (43%), Gaps = 28/204 (13%)
Query: 20 KELSLKYKQSFQEARDELVEFQEGSRELEAE---LEAQLVQAEQRNRDLQADNQRLKYEV 76
+E +L+ +++ Q+ R + E + EAE L + E R+ Q +N + +
Sbjct: 680 EEQNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRETQEENDEFRRRI 739
Query: 77 EALKEKLEHQYAQSYKQVSV---LEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
L+++L+ +V L D L + A K+QL + + ++ L AKRA
Sbjct: 740 LGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALE 799
Query: 134 VSLEDF----------EQRLNQAIERNAFL-------ESELDEKESLL-VSVQRLKDE-- 173
LE+ +Q LN+A+E ++EL+E++ LL +V RL E
Sbjct: 800 ARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELE 859
Query: 174 --ARDLRQELAVRERQQEVTRKSA 195
D +Q L + Q E ++ A
Sbjct: 860 KIGEDSKQALQQLQAQLEDYKEKA 883
Score = 37.4 bits (85), Expect = 0.020
Identities = 38/179 (21%), Positives = 82/179 (45%), Gaps = 29/179 (16%)
Query: 14 EETAYWKELSLKYKQSFQEARDELVEFQ---EGSRELEAELEAQLVQAEQRNRDLQA--- 67
EE + +EL + K Q++ EL + + +L LE Q+++ + + + +Q
Sbjct: 401 EECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEP 460
Query: 68 ----------DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE 117
+ + L EV K+++E Q ++++ L+ L + A ++Q ++VR+
Sbjct: 461 AKEVLLKDLLETRELLEEVLEGKQRVEEQLRLRERELTALKGALKEEVASRDQEVEHVRQ 520
Query: 118 LEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARD 176
Q D E+ +R+ + A + +A LE+E + +L+ +QR +E +
Sbjct: 521 --QYQRDTEQLRRS-----------MQDATQDHAVLEAERQKMSALVRGLQRELEETSE 566
Score = 37.0 bits (84), Expect = 0.026
Identities = 51/206 (24%), Positives = 92/206 (44%), Gaps = 41/206 (19%)
Query: 33 ARDELVEF--QEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEH----- 85
+RD+ VE Q+ R+ E +L + A Q + L+A+ Q++ V L+ +LE
Sbjct: 510 SRDQEVEHVRQQYQRDTE-QLRRSMQDATQDHAVLEAERQKMSALVRGLQRELEETSEET 568
Query: 86 -----QYAQSYKQVSVLEDDLSQTRAIKEQLHKYV--------RELEQANDDLERAKRAT 132
+ ++ + + + +L Q R KE++ + + RELEQA RA
Sbjct: 569 GHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVLQRELEQA-----RASAGD 623
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAV----RERQQ 188
+E ++ L + E L++E +E R +D R+L ++LAV +R +
Sbjct: 624 TRQVEVLKKELLRTQEELKELQAERQSQE----VAGRHRD--RELEKQLAVLRVEADRGR 677
Query: 189 EVTRKSAPSSPTL-----DCEKMDSA 209
E+ ++ TL DCE+ A
Sbjct: 678 ELEEQNLQLQKTLQQLRQDCEEASKA 703
Score = 37.0 bits (84), Expect = 0.026
Identities = 46/188 (24%), Positives = 86/188 (45%), Gaps = 16/188 (8%)
Query: 41 QEGSRELEAELEAQLVQ-----AEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
+ + L+ EL AQ +Q AE + R Q D R +E +LE + + V
Sbjct: 928 ERDTARLDKELLAQRLQGLEQEAENKKRS-QDDRARQLKGLEEKVSRLETELDEEKNTVE 986
Query: 96 VLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRL--NQAIERNAFL 153
+L D +++ R +QL + + A DLE K + +D + RL ++ ++ +
Sbjct: 987 LLTDRVNRGRDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSAS 1046
Query: 154 ESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKM---DSAV 210
S+L+ + LL +RL+ E R++ ++ +++ RK S ++ E+ D
Sbjct: 1047 LSQLESQNQLL--QERLQAEE---REKTVLQSTNRKLERKVKELSIQIEDERQHVNDQKD 1101
Query: 211 QASLSLPA 218
Q SL + A
Sbjct: 1102 QLSLRVKA 1109
Score = 33.1 bits (74), Expect = 0.37
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 39/180 (21%)
Query: 41 QEGSRELEAELEAQ----------LVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQS 90
+EGS E E + + LV + A L +VE L+ KL+ + +
Sbjct: 323 REGSSESETSVRRKVSLVLEKMQPLVMVSSGSTKAVAGQGELTRKVEELQRKLDEEVKKR 382
Query: 91 YK----QVSV---LEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRL 143
K QV + LE+ + ++E L + E +Q+N +L+ KR L
Sbjct: 383 QKLEPSQVGLERQLEEKTEECSRLQELLERRKGEAQQSNKELQNMKRL-----------L 431
Query: 144 NQAIERNAFLESELDEKESLLVSVQ--------RLKD--EARDLRQE-LAVRERQQEVTR 192
+Q + LE+++ E ++ L VQ LKD E R+L +E L ++R +E R
Sbjct: 432 DQGEDLRHGLETQVMELQNKLKHVQGPEPAKEVLLKDLLETRELLEEVLEGKQRVEEQLR 491
>gi|157743265 caspase recruitment domain family, member 11 [Homo
sapiens]
Length = 1154
Score = 55.1 bits (131), Expect = 9e-08
Identities = 51/196 (26%), Positives = 101/196 (51%), Gaps = 14/196 (7%)
Query: 15 ETAYWKELSLKYKQSFQEARDELVEFQEGSRELE---AELEAQLVQAEQRNRDLQADNQR 71
E ++E K K+ DELV+ ++ + L A+L + A R+RDLQ + +
Sbjct: 172 ELLTFQERYYKMKEERDSYNDELVKVKDDNYNLAMRYAQLSEEKNMAVMRSRDLQLEIDQ 231
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE---LEQANDDLERA 128
LK+ + ++E+ + + QS K L++D+ + R KEQ+ + RE L+ N +L+
Sbjct: 232 LKHRLNKMEEECKLERNQSLK----LKNDI-ENRPKKEQVLELERENEMLKTKNQELQSI 286
Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
+A SL D ++ + +E + + L++++ L+ + L++EAR +EL + ++
Sbjct: 287 IQAGKRSLPDSDKAILDILEHDR--KEALEDRQELVNRIYNLQEEARQ-AEELRDKYLEE 343
Query: 189 EVTRKSAPSSPTLDCE 204
+ + S+ DCE
Sbjct: 344 KEDLELKCSTLGKDCE 359
Score = 38.5 bits (88), Expect = 0.009
Identities = 33/124 (26%), Positives = 61/124 (49%), Gaps = 9/124 (7%)
Query: 31 QEARDELVEFQEGSRELEAELEAQLVQAEQ---RNRDLQADNQRLKYEVEALK---EKLE 84
QE + + QE +R+ E + L + E + L D + K+ + + E++E
Sbjct: 317 QELVNRIYNLQEEARQAEELRDKYLEEKEDLELKCSTLGKDCEMYKHRMNTVMLQLEEVE 376
Query: 85 HQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDD--LERAKR-ATIVSLEDFEQ 141
+ Q++ + SQ K++ K +RELE+ ND+ +E +R A IV+LE +
Sbjct: 377 RERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELEEKNDEMRIEMVRREACIVNLESKLR 436
Query: 142 RLNQ 145
RL++
Sbjct: 437 RLSK 440
Score = 35.4 bits (80), Expect = 0.075
Identities = 42/194 (21%), Positives = 81/194 (41%), Gaps = 23/194 (11%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
+ ++EE + SLK K + + E ELE E E + ++ +QA
Sbjct: 237 NKMEEECKLERNQSLKLKNDIENRPKK-----EQVLELERENEMLKTKNQELQSIIQAGK 291
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDL----SQTRAIKEQLHKYVRELEQ----- 120
+ L +A+ + LEH ++ + L + + + R +E KY+ E E
Sbjct: 292 RSLPDSDKAILDILEHDRKEALEDRQELVNRIYNLQEEARQAEELRDKYLEEKEDLELKC 351
Query: 121 --ANDDLERAK---RATIVSLEDFEQRLNQAIERNAFLESE----LDEKESLLVSVQRLK 171
D E K ++ LE+ E+ +QA +++ L EK+ ++ L+
Sbjct: 352 STLGKDCEMYKHRMNTVMLQLEEVERERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELE 411
Query: 172 DEARDLRQELAVRE 185
++ ++R E+ RE
Sbjct: 412 EKNDEMRIEMVRRE 425
>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
Length = 775
Score = 54.3 bits (129), Expect = 2e-07
Identities = 57/226 (25%), Positives = 107/226 (47%), Gaps = 36/226 (15%)
Query: 12 LKEETAYWKELSLKYKQSFQE------ARDELVEFQEGSRELEAELEA-----QLVQAEQ 60
L+EE ++L L+ +++ + A +++ F+ +++L E+E Q ++ E+
Sbjct: 254 LQEERTQRQDLELRLEETREALAGRAYAAEQMEGFELQTKQLTREVEELKSELQAIRDEK 313
Query: 61 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQ----LHKYVR 116
D + Q L+ E LK + Q Q ++ ++ ED L Q ++EQ L +
Sbjct: 314 NQPDPRL--QELQEEAARLKSHFQAQLQQEMRKTALAEDQLRQQSQVEEQRVAALENQIS 371
Query: 117 ELEQANDDLERAKRATIVSLEDFEQRL------NQAIERNAFLESELD---EKESLLVSV 167
E+ + E+AK+ ++++ ++R+ N+ + A S LD E+ SL V+V
Sbjct: 372 EVSELLGTYEKAKQKDQLAIQKLKERILQLDLENKTLALAASSRSPLDSHGEESSLDVNV 431
Query: 168 QRLKDEARDLRQELAVRERQQEVT--------RKSAPSSPTLDCEK 205
LKD+ L++ L V R+ +VT + PSS D EK
Sbjct: 432 --LKDKMEKLKRLLQVAARKSQVTLDVEKLCDLEIMPSSEAADGEK 475
>gi|169217489 PREDICTED: similar to phosphodiesterase 4D interacting
protein [Homo sapiens]
Length = 211
Score = 53.1 bits (126), Expect = 3e-07
Identities = 45/154 (29%), Positives = 81/154 (52%), Gaps = 14/154 (9%)
Query: 64 DLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDD---LSQTRAIKEQLHKYVRELEQ 120
+L+ Q+L+ E++ ++L A+ Y ++ E + L+ + + KEQL + REL Q
Sbjct: 3 ELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQ 62
Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQ- 179
D+ ++ A + LE QR+ ++ LE +DEK S L+++ ++LRQ
Sbjct: 63 YRDNSDKTLEANEMLLEKLRQRIR---DKAVALERAIDEKFS------ALEEKEKELRQL 113
Query: 180 ELAVRERQQEVTR-KSAPSSPTLDCEKMDSAVQA 212
LAVRER ++ R + SS + M+S ++A
Sbjct: 114 RLAVRERDHDLERLRDVLSSNEATMQTMESLLRA 147
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 53.1 bits (126), Expect = 3e-07
Identities = 52/192 (27%), Positives = 93/192 (48%), Gaps = 25/192 (13%)
Query: 14 EETAYWKELSLKYKQSFQEARD---ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
E T++ +LSL+ K+ QE D EL QE + + E L Q E +LQ
Sbjct: 515 ELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIE----NLQETET 570
Query: 71 RLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKR 130
+L+ E+E ++E+L+ + + ++ E++ + R E +KY+ EL+Q N L++
Sbjct: 571 QLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGT 630
Query: 131 ATIVSLEDFEQRLNQAI-----------ERNAFLESELDEK----ESLLVSVQRLK---D 172
A L +E ++N+ E + E+++K E+LL V++ K D
Sbjct: 631 AESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKVIAD 690
Query: 173 EARDLRQELAVR 184
EA L++E+ R
Sbjct: 691 EAVKLQKEIDKR 702
Score = 45.8 bits (107), Expect = 6e-05
Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 10/172 (5%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LKE A E + KY+ +E R ++ ++ E VQAE ++ +
Sbjct: 186 LKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKE 245
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
+++ L+++ + + KQVS+L L Q + ++ LE++ D + + +
Sbjct: 246 DYEKIQHLEQEYKKEINDKEKQVSLL---LIQITEKENKMKDLTFLLEESRDKVNQLEEK 302
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAV 183
T + E+ L Q+IE+ L EL E + VS+QR + L ++L +
Sbjct: 303 TKLQSEN----LKQSIEKQHHLTKEL---EDIKVSLQRSVSTQKALEEDLQI 347
Score = 42.0 bits (97), Expect = 8e-04
Identities = 47/233 (20%), Positives = 101/233 (43%), Gaps = 27/233 (11%)
Query: 2 DGEDIPDFSSLKEETAYWKELSLKYKQSFQEA-RDELVEFQEGSRELEAELEAQLVQAEQ 60
+ E I + E KE L+ + EA R + E Q G+ ++ +LE + Q
Sbjct: 112 EAEKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGI----Q 167
Query: 61 RNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
N+DL +N ++ LKE A+S ++ E + +TR + L+ + ++
Sbjct: 168 ENKDLIKENNATRHLCNLLKETC----ARSAEKTKKYEYEREETRQVYMDLNNNIEKMIT 223
Query: 121 ANDDLERAKRATIVSL---------------EDFEQRLNQAIERNAFLESELDEKESLLV 165
A ++L + + + +++++ +N ++ + L ++ EKE+ +
Sbjct: 224 AFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMK 283
Query: 166 SVQRLKDEARDLRQELAVRERQQEVTRKSAPSSP---TLDCEKMDSAVQASLS 215
+ L +E+RD +L + + Q K + T + E + ++Q S+S
Sbjct: 284 DLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVS 336
Score = 36.2 bits (82), Expect = 0.044
Identities = 43/207 (20%), Positives = 90/207 (43%), Gaps = 42/207 (20%)
Query: 21 ELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQA---EQRNRDL-----------Q 66
E+ K K+ +++ + E+++ + E ++ L+Q E + +DL
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKVN 297
Query: 67 ADNQRLKYEVEALKEKLE--HQYAQSYKQVSV-LEDDLSQTRAIKEQLHKYVREL----E 119
++ K + E LK+ +E H + + + V L+ +S +A++E L + + E
Sbjct: 298 QLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIATKTICQLTE 357
Query: 120 QANDDLERAKRA-------------TIVSLEDFEQRLNQAIERN----AFLESELDEKES 162
+ +E + +A T+ SLE+ + Q +E+N L EL +K S
Sbjct: 358 EKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSS 417
Query: 163 LLVSVQRLKD----EARDLRQELAVRE 185
L + +L + E +L++ L +E
Sbjct: 418 ELEEMTKLTNNKEVELEELKKVLGEKE 444
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 52.4 bits (124), Expect = 6e-07
Identities = 45/167 (26%), Positives = 81/167 (48%), Gaps = 23/167 (13%)
Query: 34 RDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEAL---KEKLEHQYAQS 90
++ L+E + RE+ E E Q ++ +++ +LQ Q + ++ AL + LE Q Q+
Sbjct: 848 KNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQA 907
Query: 91 YKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER---AKRATIVSLEDFEQRLNQAI 147
+ +L +T A E+ ++ L D+++R A R + + D E++LNQ
Sbjct: 908 -------KTELEETTAEAEE---EIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLT 957
Query: 148 ERNA-------FLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
E NA +L +LDE + +L+ E LR+E+ RE Q
Sbjct: 958 EDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQ 1004
Score = 31.2 bits (69), Expect = 1.4
Identities = 34/127 (26%), Positives = 57/127 (44%), Gaps = 13/127 (10%)
Query: 75 EVEALKEKLEHQYAQSYKQVSVLEDDL----SQTRAIKEQLHKYVRELEQANDD----LE 126
EVEA+ + E + S Q S+LE DL ++ ++K L + E+ Q +D L
Sbjct: 481 EVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLH 540
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKD--EARDLRQELAVR 184
+ + E EQ +E + ++L+E LVS +R D E+ LA
Sbjct: 541 DIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEED---LVSARRRSDLYESELRESRLAAE 597
Query: 185 ERQQEVT 191
E +++ T
Sbjct: 598 EFKRKAT 604
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 52.0 bits (123), Expect = 8e-07
Identities = 46/193 (23%), Positives = 90/193 (46%), Gaps = 7/193 (3%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
L+ E +E LK ++ + + L Q+ RE E E L + E++ + + QR
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 72 LKYEVEALKEKL-EHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYV----RELEQANDDLE 126
LK E E +++L + + + +++ +++ + R +E++ + RE ++ E
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 127 RAKRATIVSLEDFEQRLNQAI--ERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVR 184
+R ++ E+ E+R Q + E+ E L +E QRLK E + R+E +
Sbjct: 627 EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELA 686
Query: 185 ERQQEVTRKSAPS 197
E +QE R+ S
Sbjct: 687 EEEQEQARERIKS 699
Score = 47.4 bits (111), Expect = 2e-05
Identities = 51/192 (26%), Positives = 83/192 (43%), Gaps = 21/192 (10%)
Query: 4 EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVE--FQEGSRELEAELEAQLVQAEQR 61
E+ PD L+ EL K ++ Q+ R E + FQE + + E L + E++
Sbjct: 202 EEFPDEEQLRRRELL--ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Query: 62 NRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQA 121
++ + QR E E KLE Q + +Q E++ Q R +EQ + +E E+
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQ----EEEQQQQRLRREQQLRRKQEEERR 315
Query: 122 NDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
ER E E+R Q R L E +E+ Q+L+ E + R+E
Sbjct: 316 EQQEERR--------EQQERREQQEERREQQLRREQEERRE-----QQLRREQEEERREQ 362
Query: 182 AVRERQQEVTRK 193
+R Q+E R+
Sbjct: 363 QLRREQEEERRE 374
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/178 (28%), Positives = 81/178 (45%), Gaps = 9/178 (5%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEA-ELEAQLVQAEQRNRDLQADNQR 71
K ET KE ++ Q R EL E +E R+LE EL + + EQ+ + L+ + Q
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQR-ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
+ + E +E+ E + Q ++ E Q R +E+ R +Q + E +R
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEE-----RREQQLRREQEEERRE 361
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELD-EKESLLVSVQRLKDEARDLRQELAVRERQQ 188
+ E E+R Q + R L E +E L Q+L+ E + LR+E +R QQ
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE-QQLRREQQLRREQQ 418
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 16/177 (9%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
L+ E +E L+ +Q + + +L Q+ RE + E QL + +Q R+ + +
Sbjct: 377 LRREQQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRA 131
K+E E +++L+ + + + R + + H+ R +Q D E +R
Sbjct: 436 QKHEQERREQRLKREQEERRDWLK---------REEETERHEQERRKQQLKRDQEEERRE 486
Query: 132 TIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQ 188
+ LE+ E+R Q R L E +E+ QRLK + + R + +R QQ
Sbjct: 487 RWLKLEE-EERREQQERREQQLRREQEERRE-----QRLKRQEEEERLQQRLRSEQQ 537
Score = 45.1 bits (105), Expect = 1e-04
Identities = 42/185 (22%), Positives = 89/185 (48%), Gaps = 18/185 (9%)
Query: 20 KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR----DLQADNQRLK-- 73
KEL ++ + R+ + QE L+ + E + Q ++R++ L+ + +R +
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 74 -YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
Y AL+E+L + ++ L+ + + R +EQ +Y RE EQ + E+ R
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY-REEEQLQQEEEQLLR-- 945
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQ----RLKDEARDLRQELAVRERQQ 188
E+ E+R Q ER + +L +KE L+ + R ++ + R+E +++ ++
Sbjct: 946 ----EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Query: 189 EVTRK 193
++ R+
Sbjct: 1002 QLLRE 1006
Score = 42.4 bits (98), Expect = 6e-04
Identities = 48/205 (23%), Positives = 92/205 (44%), Gaps = 34/205 (16%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA----- 67
+EE +E L ++ + R E EL+ E E QL++ E+ R LQ
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE-EEQLLREEREKRRLQERERQY 1050
Query: 68 -DNQRLKYEVEAL---------KEKLEHQYA-----QSYKQVSVLEDDLSQTRAIKEQLH 112
+ + L+ E E L +++LE QY Q ++ + E+ + R +E+
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQC 1110
Query: 113 KYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLV----SVQ 168
+ EL+Q + L R +R E+R Q +ER E E+ ++E L+ +
Sbjct: 1111 REEEELQQEEEQLLREER---------EKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 169 RLKDEARDLRQELAVRERQQEVTRK 193
R ++ R R+E +++ ++++ R+
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLRE 1186
Score = 40.4 bits (93), Expect = 0.002
Identities = 45/186 (24%), Positives = 86/186 (46%), Gaps = 14/186 (7%)
Query: 13 KEETAYWKELSLKYK---QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
+E+ +EL K++ Q QE E + QE R++ LE + ++ E+ + L+
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKI---LEEEQLRPEREEQQLRRQE 1768
Query: 70 QRLKY-EVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERA 128
+ K+ E E L+++ E Q +S + ++ Q R +E+ ++L D +
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREE-EQLRQEREE-----QQLRPQQRDGKYR 1822
Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRL-KDEARDLRQELAVRERQ 187
+ LE+ EQRL Q +R E + +E Q L ++E + RQE + R+
Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Query: 188 QEVTRK 193
+ + R+
Sbjct: 1883 EHIRRQ 1888
Score = 37.4 bits (85), Expect = 0.020
Identities = 35/180 (19%), Positives = 75/180 (41%), Gaps = 7/180 (3%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
L+ E +E L+ +Q + +L QE R E QL + +Q R+ Q ++
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERR-----EQQLRREQQLRREQQLRREQ 393
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK-- 129
+ L+ + + + Q ++ L + R +E+ H+ E E+ L+R +
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE 453
Query: 130 RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
R + E+ +R Q + + +E+ + ++ + + R+E +R Q+E
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEE 513
Score = 37.0 bits (84), Expect = 0.026
Identities = 55/200 (27%), Positives = 91/200 (45%), Gaps = 24/200 (12%)
Query: 4 EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAE-LEAQLVQAEQRN 62
E+ D+ +EET E + ++ Q RD+ E +E +LE E Q + EQ+
Sbjct: 452 EERRDWLKREEET----ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507
Query: 63 RDLQAD--NQRLK--YEVEALKEKLEHQY----AQSYKQVSVLEDDLSQTRAIKEQLHKY 114
R Q + QRLK E E L+++L + Q ++ +L+ + + + + +
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
Query: 115 VRELEQANDDL---ERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLK 171
RE E+ D L E +R + E E+RL Q ++R E +E+ QRLK
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQ-EERLEQRLKREEVERLEQEERRE-----QRLK 621
Query: 172 DE--ARDLRQELAVRERQQE 189
E + RQ+L E Q+E
Sbjct: 622 REEPEEERRQQLLKSEEQEE 641
Score = 36.6 bits (83), Expect = 0.034
Identities = 49/203 (24%), Positives = 90/203 (44%), Gaps = 15/203 (7%)
Query: 13 KEETAYWKELSLKYK---QSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
+EE +E K++ Q QE ++ + QE R+ E +L EQ + L+ +
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE---ELRHQEQGRKFLEEEQ 1381
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK 129
+ + E E K E Q ++ + +D + R ++QL + R+ + ++ + +
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRR 1441
Query: 130 RATIVSLEDFEQRLNQAIERNAFLESE--LDEKESLLVSVQR-----LKDEARDLRQELA 182
+ + EQ+L Q R F E E L E+E + Q L++E + RQE
Sbjct: 1442 QERERKFLEEEQQLRQERHRK-FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERD 1500
Query: 183 VRERQQEVTRKSAPSSPTLDCEK 205
+ R+QE+ R P L+ E+
Sbjct: 1501 RKFREQEL-RSQEPERKFLEEEQ 1522
Score = 36.2 bits (82), Expect = 0.044
Identities = 43/193 (22%), Positives = 82/193 (42%), Gaps = 31/193 (16%)
Query: 27 KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEV---------- 76
+Q QE ++ + QE R+ LE Q V+ +++ R D Q+L+ +
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFR--LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 77 -------EALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVR--------ELEQA 121
+ L+E+ E Q + + LE++ R +EQ ++ R +L Q
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 122 NDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQEL 181
++ + ++ + EQ+L + FL+ +E++ ++R E LRQE
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQ---EEQQLRRQELERKFREEEQLRQET 1735
Query: 182 AVRE-RQQEVTRK 193
+ R+QE RK
Sbjct: 1736 EQEQLRRQERYRK 1748
Score = 35.4 bits (80), Expect = 0.075
Identities = 48/195 (24%), Positives = 79/195 (40%), Gaps = 35/195 (17%)
Query: 28 QSFQEARDELVEFQEGSRELEAELEA----QLVQAEQRNR-----------DLQADNQRL 72
Q QE D L E QE R E + QL + +R R L+ + Q L
Sbjct: 847 QQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLL 906
Query: 73 KYEVEAL------KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
+ E E L K + + Q Q ++ + +++ R +E+ + RE + D
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELD-EKESLLVSVQ------------RLKDE 173
+ K ++ E+ E+R Q E+ E EL E+E LL + R KDE
Sbjct: 967 QQKEEQLLG-EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 174 ARDLRQELAVRERQQ 188
+ ++L ER++
Sbjct: 1026 LQQEEEQLLREEREK 1040
Score = 35.4 bits (80), Expect = 0.075
Identities = 45/209 (21%), Positives = 85/209 (40%), Gaps = 41/209 (19%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR--------- 63
+EE +E L ++ + R EL EL+ E E QL++ EQ R
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE-EEQLLREEQEKRRQERERQYR 1200
Query: 64 ---DLQADNQRLKYEVEALKEKLEHQY----------------AQSYKQVSVLEDDLSQT 104
+LQ ++ +Y E + L+ Q+ + +Q LED +
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260
Query: 105 RAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLL 164
R ++ L + E ++ + + ER + ++QR E + E +E++
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRR---------WQQRDRHFPEEE---QLEREEQKEAK 1308
Query: 165 VSVQRLKDEARDLRQELAVRERQQEVTRK 193
++ ++E + LR+E + R+QE RK
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRK 1337
Score = 35.0 bits (79), Expect = 0.098
Identities = 40/169 (23%), Positives = 81/169 (47%), Gaps = 14/169 (8%)
Query: 27 KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQ 86
+Q ++ RD +F+E + L+ E QL + E+ + L+ + Q + E E ++L H
Sbjct: 1610 QQQLRQERDR--KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE---QQLRHD 1664
Query: 87 YAQSYKQVSVLEDDLSQTRAIKEQLHKYVRE--LEQANDDLERAKRATIVSLEDFEQRLN 144
+ +++ E+ L Q ++QL + R+ + L R +R L++ +Q
Sbjct: 1665 RDRKFRE----EEQLLQ-EGEEQQLRRQERDRKFREEEQQLRRQERER-KFLQEEQQLRR 1718
Query: 145 QAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
Q +ER F E E +E+ ++R + + L +E ER+++ R+
Sbjct: 1719 QELERK-FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Score = 34.7 bits (78), Expect = 0.13
Identities = 41/177 (23%), Positives = 81/177 (45%), Gaps = 14/177 (7%)
Query: 27 KQSFQEARDELVEFQEGSREL-EAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEH 85
+Q ++ RD +F+E ++L E E + +Q EQ+ R + + ++ + E + +E +
Sbjct: 1682 QQLRRQERDR--KFREEEQQLRRQERERKFLQEEQQLRRQELE-RKFREEEQLRQETEQE 1738
Query: 86 QYAQSYKQVSVLEDDLSQTRAIKEQLHKY-----VRELEQANDDLERAKRATIVSLEDF- 139
Q + + +LE++ + ++QL + RE EQ + E + + S F
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
Query: 140 -EQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSA 195
E++L Q E + D K +L+++ + LRQE R+RQ + A
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQE---RDRQYRAEEQFA 1852
Score = 34.3 bits (77), Expect = 0.17
Identities = 38/191 (19%), Positives = 86/191 (45%), Gaps = 20/191 (10%)
Query: 20 KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVE-- 77
+EL + +Q +E +++ + +E E EL+ Q + R+ D ++D LK++ E
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD---LKWQWEPE 1230
Query: 78 ---ALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK----- 129
A+++ + + +Q LED + R ++ L + E ++ + + ER +
Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290
Query: 130 -------RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELA 182
+ ++ ++R ++ E L E +EK + ++ ++E + L++
Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
Query: 183 VRERQQEVTRK 193
R+QE RK
Sbjct: 1351 QPLRRQERDRK 1361
Score = 30.8 bits (68), Expect = 1.9
Identities = 45/189 (23%), Positives = 83/189 (43%), Gaps = 18/189 (9%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
KEE +E L ++ + R E EL+ E E QL++ E+ R Q ++
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE-EEQLLREEREKRRRQELERQY 1140
Query: 73 KYEVEA-------LKEKLEHQYAQSYKQVSVLEDDLSQ--TRAIKEQLHKYVRELE---Q 120
+ E E L+E+ E + Q ++ E++L Q + ++E+ K +E E +
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
++L+R KR ED L E E E +++ + R ++ R L ++
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWEP----EKENAVRDNKVYCKGRENEQFRQL-ED 1255
Query: 181 LAVRERQQE 189
+R+RQ +
Sbjct: 1256 SQLRDRQSQ 1264
>gi|119120918 coiled-coil domain containing 64 [Homo sapiens]
Length = 573
Score = 51.6 bits (122), Expect = 1e-06
Identities = 43/174 (24%), Positives = 84/174 (48%), Gaps = 23/174 (13%)
Query: 20 KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEAL 79
+++S +Y+Q +E D+L ++ EL E + + E R +L++D V+ L
Sbjct: 125 QDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELESD-------VKQL 177
Query: 80 KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQAN--DDLERAKRATIVSL- 136
+++LE Q Q+ + E D ++RA++E + R L+Q + ++ER + +L
Sbjct: 178 QDELERQ------QIHLREADREKSRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALR 231
Query: 137 EDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEV 190
EDF E+N+ + ESL ++ L D R+L L+ + ++
Sbjct: 232 EDFR-------EKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDL 278
Score = 38.1 bits (87), Expect = 0.012
Identities = 45/208 (21%), Positives = 90/208 (43%), Gaps = 20/208 (9%)
Query: 21 ELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRD-------LQADNQRLK 73
EL +++ E + E + ++L+ ELE Q + + +R+ L NQRL
Sbjct: 151 ELRRRFENREGEWEGRVSELESDVKQLQDELERQQIHLREADREKSRAVQELSEQNQRLL 210
Query: 74 YEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQ-------LHKYVRELEQANDDLE 126
++ E +E Q + QV L +D + + Q L ++ L +LE
Sbjct: 211 DQLSRASE-VERQLSM---QVHALREDFREKNSSTNQHIIRLESLQAEIKMLSDRKRELE 266
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEAR-DLRQ-ELAVR 184
AT+ + + + + +R LE + +K+ L Q E R RQ ++ V
Sbjct: 267 HRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLELQEVRLSCRQLQVKVE 326
Query: 185 ERQQEVTRKSAPSSPTLDCEKMDSAVQA 212
E +E + +S+ ++ T +++ +++A
Sbjct: 327 ELTEERSLQSSAATSTSLLSEIEQSMEA 354
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 51.2 bits (121), Expect = 1e-06
Identities = 40/160 (25%), Positives = 85/160 (53%), Gaps = 6/160 (3%)
Query: 31 QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQS 90
+E R L ++ E+ +LEA++ + E+R + LQA+ ++++ ++ L+E+LE + +S
Sbjct: 900 EELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEE--ES 957
Query: 91 YKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERN 150
+Q LE ++ + K + + + LE N L + K+ + +F L + E++
Sbjct: 958 ARQKLQLEKVTTEAKLKKLEEEQII--LEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015
Query: 151 AFLESELDEKESLLVSV-QRLKDEARDLRQELAVRERQQE 189
L ++ E+++ + +RL+ E + RQEL R+ E
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQ-RQELEKTRRKLE 1054
Score = 46.6 bits (109), Expect = 3e-05
Identities = 43/170 (25%), Positives = 79/170 (46%), Gaps = 14/170 (8%)
Query: 27 KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQ--RNRDLQADNQR--LKYEVEALKEK 82
K +E DEL ++ LE L+A Q E+ + RD Q++ ++ L +V ++ +
Sbjct: 1538 KTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE 1597
Query: 83 LEHQYAQSYKQVSV---LEDDLSQTRAI-------KEQLHKYVRELEQANDDLERAKRAT 132
LE + Q V+ LE DL A +++ K +R+L+ D R T
Sbjct: 1598 LEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDT 1657
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELA 182
S E+ + + ++ +E+E+ + + L + +R K +A+ R ELA
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELA 1707
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/206 (22%), Positives = 94/206 (45%), Gaps = 11/206 (5%)
Query: 25 KYKQSFQEARDEL----VEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALK 80
K +Q ++ R +L + + EL+A++ +Q ++ +LQA R++ E A K
Sbjct: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEA-AQK 1099
Query: 81 EKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVS-LEDF 139
+ + Q+S L++DL RA + + K R+L + + L+ T+ S
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 140 EQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVR-ERQQEVTRKSAPSS 198
E R + E N ++ +E ++ +Q ++ + +ELA + E+ + V +
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219
Query: 199 PTLDCEKMDSAVQASLSLPATPVGKG 224
TL+ E+ + A + + L GKG
Sbjct: 1220 QTLENERGELANEVKVLLQ----GKG 1241
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/204 (21%), Positives = 90/204 (44%), Gaps = 17/204 (8%)
Query: 11 SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
+L+EE + + +Q +A +EL E E ++ ++A LE + + L+ +
Sbjct: 1175 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLE-------KAKQTLENERG 1227
Query: 71 RLKYEVEAL---KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDD--- 124
L EV+ L K EH+ + Q+ L+ ++ ++ +L V +L+ D+
Sbjct: 1228 ELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTG 1287
Query: 125 -LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAV 183
L ++ + +DF +Q + L+ E +K SL +++++DE R++L
Sbjct: 1288 LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQL-- 1345
Query: 184 RERQQEVTRKSAPSSPTLDCEKMD 207
E ++E TL + D
Sbjct: 1346 -EEEEEAKHNLEKQIATLHAQVAD 1368
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/164 (24%), Positives = 73/164 (44%), Gaps = 15/164 (9%)
Query: 49 AELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIK 108
AE L + E++++ L +LK + EA+ LE + + KQ LE +
Sbjct: 1002 AEFTTNLTEEEEKSKSLA----KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDS 1057
Query: 109 EQLHKYVRELEQANDDL-------ERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKE 161
L + EL+ +L E +A + +E+ + N A+++ LES++ E +
Sbjct: 1058 TDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQ 1117
Query: 162 SLLVSVQRLKDEA----RDLRQELAVRERQQEVTRKSAPSSPTL 201
L S + +++A RDL +EL + + E T S + L
Sbjct: 1118 EDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQEL 1161
Score = 40.4 bits (93), Expect = 0.002
Identities = 48/181 (26%), Positives = 86/181 (47%), Gaps = 27/181 (14%)
Query: 27 KQSFQEARDELVEFQEGSRELEAE---LEAQLVQAEQRNRDLQADNQRLKYEVE------ 77
+ S +E + E ++ + +EAE L+ +L AE+ R Q + L E+
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 78 --ALKEK--LEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATI 133
AL+EK LE + AQ ++ LE++ T I ++L K +++Q N DL +R+
Sbjct: 1718 ALALEEKRRLEARIAQLEEE---LEEEQGNTELINDRLKKANLQIDQINTDL-NLERSHA 1773
Query: 134 VSLEDFEQRLNQAIERNAFLESELDEKESLL-----VSVQRLKDEARDLRQEL--AVRER 186
E+ Q+L + +N L+ +L E E + S+ L+ + L ++L +ER
Sbjct: 1774 QKNENARQQLER---QNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKER 1830
Query: 187 Q 187
Q
Sbjct: 1831 Q 1831
Score = 37.4 bits (85), Expect = 0.020
Identities = 53/233 (22%), Positives = 97/233 (41%), Gaps = 31/233 (13%)
Query: 4 EDIPDFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQ-----A 58
+D+ S EE + K K Q+ D+L+ + R+ LE + + A
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 1451
Query: 59 EQRNRDLQADNQRLKYEVEALKEK-----LEHQYAQSYKQVSVLE-------DDLSQTRA 106
E++ + +R + E EA +++ L ++ +Q + LE ++ +
Sbjct: 1452 EEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS 1511
Query: 107 IKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVS 166
K+ + K V ELE++ LE+ LE+ E L QA E D K L V+
Sbjct: 1512 SKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDEL-QATE---------DAKLRLEVN 1561
Query: 167 VQRLKDEARDLRQELAVRERQQEVTRKS-APSSPTLDCEKMDSAVQASLSLPA 218
+Q +K + ++L R+ Q E +K ++ E D Q S+++ A
Sbjct: 1562 LQAMKAQ---FERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAA 1611
Score = 37.0 bits (84), Expect = 0.026
Identities = 46/183 (25%), Positives = 86/183 (46%), Gaps = 23/183 (12%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
LK W L K K Q +R E E+ A+ E +LV+ R + L A+N+
Sbjct: 820 LKLRNWQWWRLFTKVKPLLQVSRQE--------EEMMAK-EEELVKV--REKQLAAENRL 868
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE---RA 128
E+E L+ +L + Q +Q+ + ++ ++ +L +ELE+ DLE
Sbjct: 869 T--EMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEE 926
Query: 129 KRATIVSLEDFEQRLNQAIERNAFLESELDEKESL--LVSVQRLKDEA--RDLRQELAVR 184
+ L+ ++++ Q I+ LE +L+E+ES + ++++ EA + L +E +
Sbjct: 927 EEERCQHLQAEKKKMQQNIQE---LEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIIL 983
Query: 185 ERQ 187
E Q
Sbjct: 984 EDQ 986
Score = 33.9 bits (76), Expect = 0.22
Identities = 38/183 (20%), Positives = 82/183 (44%), Gaps = 22/183 (12%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELE---AQLVQAEQRNRDLQADN 69
K+ A +EL +K+ + + R EL + +L+ EL+ L Q++ ++ L D
Sbjct: 1248 KKVEAQLQELQVKFNEG-ERVRTELAD---KVTKLQVELDNVTGLLSQSDSKSSKLTKDF 1303
Query: 70 QRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK 129
L+ +++ +E L+ + Q + L+ + + +EQL E E+A +LE+
Sbjct: 1304 SALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE----EEEEAKHNLEKQI 1359
Query: 130 RATIVSLEDFEQRLNQAI-------ERNAFLESELD----EKESLLVSVQRLKDEARDLR 178
+ D ++++ ++ E L+ +L+ E + + +L+ L+
Sbjct: 1360 ATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQ 1419
Query: 179 QEL 181
QEL
Sbjct: 1420 QEL 1422
Score = 29.6 bits (65), Expect = 4.1
Identities = 33/150 (22%), Positives = 67/150 (44%), Gaps = 21/150 (14%)
Query: 20 KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEAL 79
KEL +K ++ + + ++ LEA++ Q + ++ QA ++++ + L
Sbjct: 1788 KELKVKLQEMEGTVKSK---YKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKL 1844
Query: 80 KEKL-----EHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIV 134
K+ L E + A+ YK + D + TR L + R+LE+A ++ +RA
Sbjct: 1845 KDVLLQVDDERRNAEQYKD----QADKASTR-----LKQLKRQLEEAEEEAQRAN----A 1891
Query: 135 SLEDFEQRLNQAIERNAFLESELDEKESLL 164
S ++ L A E + E+ ++ L
Sbjct: 1892 SRRKLQRELEDATETADAMNREVSSLKNKL 1921
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 51.2 bits (121), Expect = 1e-06
Identities = 41/189 (21%), Positives = 94/189 (49%), Gaps = 10/189 (5%)
Query: 20 KELSLKYKQSFQEARDE-------LVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
+++ ++ +QS QE+++E L+E + + E + L AE+ ++ Q +++
Sbjct: 318 QKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKV 377
Query: 73 KYEVE---ALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK 129
++E A +E LE K+ L++ ++ E L + +R+L++ N++ +
Sbjct: 378 AEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKL 437
Query: 130 RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
R V + +L ++ + LESEL+ K+ +L L +E R+L+ +A + + +
Sbjct: 438 RIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLD 497
Query: 190 VTRKSAPSS 198
+ ++ SS
Sbjct: 498 LCQQEIESS 506
Score = 43.9 bits (102), Expect = 2e-04
Identities = 46/189 (24%), Positives = 89/189 (47%), Gaps = 25/189 (13%)
Query: 15 ETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR---DLQADNQR 71
+T K++S K +Q Q+ R+ E R++E + E+ +A+ + + +L ++
Sbjct: 932 QTKLEKQVS-KLEQELQKQRESSAE---KLRKMEEKCESAAHEADLKRQKVIELTGTARQ 987
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDD-------LSQTRAIKEQLHKYVRELEQANDD 124
+K E++ KE+L ++ K++ L+ D LSQ I +Q + + A +
Sbjct: 988 VKIEMDQYKEEL----SKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKE 1043
Query: 125 LERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVR 184
LE+ + +T E L +A+++ LE+EL L S R E RD+ Q+ +
Sbjct: 1044 LEKLQHST-------ETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLS 1096
Query: 185 ERQQEVTRK 193
++ T K
Sbjct: 1097 LEEKYTTIK 1105
Score = 40.8 bits (94), Expect = 0.002
Identities = 45/175 (25%), Positives = 78/175 (44%), Gaps = 17/175 (9%)
Query: 14 EETAYWKELSLKY-KQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
E T EL LK + + D+L +E RE E + + Q ++++ QR+
Sbjct: 1168 EGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRM 1227
Query: 73 KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTR--------AIKEQLHKYV---RELEQA 121
K E+E++ ++ E A YK+ L +L TR + E H+ V RE+E+
Sbjct: 1228 K-EMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERL 1286
Query: 122 NDDLERAKRAT---IVSLEDFEQRLNQAIERNAFLESELD-EKESLLVSVQRLKD 172
+ +LE K+ + + L + R A LE+ + E + L V+ LK+
Sbjct: 1287 SSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKE 1341
Score = 38.1 bits (87), Expect = 0.012
Identities = 30/142 (21%), Positives = 64/142 (45%), Gaps = 7/142 (4%)
Query: 45 RELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVL---EDDL 101
RE E+E ++++ E + + + ++E+L +KL++ Q ++ ++ E ++
Sbjct: 1154 REHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEI 1213
Query: 102 SQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKE 161
SQ + E+ + ++E+E + E+ D Q L E+ +EL E
Sbjct: 1214 SQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEAR 1273
Query: 162 SLLV----SVQRLKDEARDLRQ 179
V ++RL E D++Q
Sbjct: 1274 HQQVQAQREIERLSSELEDMKQ 1295
Score = 37.4 bits (85), Expect = 0.020
Identities = 49/202 (24%), Positives = 90/202 (44%), Gaps = 33/202 (16%)
Query: 31 QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEK-------- 82
Q+A+ L E ++L AEL ++ E + ++L +Q LK LK++
Sbjct: 1091 QKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLD 1150
Query: 83 --LEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK----RATIVSL 136
+ + +++ LE L ++ +L + +++E ND L+ AK + L
Sbjct: 1151 MTIREHRGEMEQKIIKLEGTLEKSEL---ELKECNKQIESLNDKLQNAKEQLREKEFIML 1207
Query: 137 EDFEQ--RLNQAIERN----AFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEV 190
++ ++ +L + IER +ES + E+E + + + EA DL QEL +
Sbjct: 1208 QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYK---EAIDLGQEL-------RL 1257
Query: 191 TRKSAPSSPTLDCEKMDSAVQA 212
TR+ +S T E VQA
Sbjct: 1258 TREQVQNSHTELAEARHQQVQA 1279
Score = 36.2 bits (82), Expect = 0.044
Identities = 30/152 (19%), Positives = 70/152 (46%), Gaps = 8/152 (5%)
Query: 50 ELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKE 109
EL +L+Q E N DL+ + + + ++E+L + + S K S + SQ +++
Sbjct: 645 ELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEK 704
Query: 110 QLHKYV---RELEQANDDLERAKRATIVSLEDFEQRLNQAIER--NAFLESE---LDEKE 161
QL + + + N +LE+ + E +N E+ AF +++ L++ +
Sbjct: 705 QLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHK 764
Query: 162 SLLVSVQRLKDEARDLRQELAVRERQQEVTRK 193
+ ++RL+ + Q+ +E+ + ++
Sbjct: 765 EMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQ 796
Score = 32.7 bits (73), Expect = 0.49
Identities = 42/177 (23%), Positives = 78/177 (44%), Gaps = 10/177 (5%)
Query: 27 KQSFQEARDELVEFQEGSRELEAELEA-QLVQAEQRNRDLQADNQRLKYEVEALKEKLEH 85
K E R +L + ++L A L A QL Q+ D Q ++ E E +K H
Sbjct: 556 KLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLG-GH 614
Query: 86 QYAQSYKQVSV------LEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDF 139
Q A+S K + E + + E+L + ++E N DL+ +
Sbjct: 615 QVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLI 674
Query: 140 EQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVR--ERQQEVTRKS 194
++ L + ++ LESE+ +K S L+++++ +E +A + E +QE+ K+
Sbjct: 675 QEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKN 731
Score = 32.7 bits (73), Expect = 0.49
Identities = 38/189 (20%), Positives = 82/189 (43%), Gaps = 15/189 (7%)
Query: 10 SSLKEETAYWKELSLKYKQSF---QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQ 66
S +KE+ Y ++ +YK++ QE R + Q EL AE Q VQA Q
Sbjct: 1232 SVMKEQEQY---IATQYKEAIDLGQELRLTREQVQNSHTEL-AEARHQQVQA-------Q 1280
Query: 67 ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLE 126
+ +RL E+E +K+ + + A L + ++ ++ +++L + L+
Sbjct: 1281 REIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLK 1340
Query: 127 RAKRATIVSLEDFEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRE 185
A ++S ++ + + + +L+E+ E + ++ +D +L Q++ R
Sbjct: 1341 EAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRN 1400
Query: 186 RQQEVTRKS 194
E ++
Sbjct: 1401 EVIEAANEA 1409
Score = 30.8 bits (68), Expect = 1.9
Identities = 35/188 (18%), Positives = 76/188 (40%), Gaps = 20/188 (10%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELE-------AQLVQAEQRNRDL 65
KE+ + + L+ +Q + + E+ Q+ +E+E+ ++ Q +A ++L
Sbjct: 1196 KEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQEL 1255
Query: 66 QADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ----- 120
+ ++++ L E HQ Q+ +++ L +L + + ++ + L +
Sbjct: 1256 RLTREQVQNSHTELAE-ARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGAS 1314
Query: 121 --ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEK-----ESLLVSVQRLKDE 173
LE +A I L + L +A E K +S SVQ+L ++
Sbjct: 1315 KVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQ 1374
Query: 174 ARDLRQEL 181
+ EL
Sbjct: 1375 LEKAKLEL 1382
Score = 30.4 bits (67), Expect = 2.4
Identities = 29/162 (17%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 32 EARDELVEFQEGSRELEA---ELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYA 88
+ + EL + +ELE E +L +A Q+ L+ + Q E+++ +L+
Sbjct: 1029 QTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRD 1088
Query: 89 QSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIE 148
K LE+ + + + +L + E+E +L +A + +QR Q
Sbjct: 1089 VLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTH 1148
Query: 149 RNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEV 190
+ + E E ++ ++ + + EL ++E +++
Sbjct: 1149 LDMTIREHRGEMEQKIIKLEGTLE-----KSELELKECNKQI 1185
Score = 28.9 bits (63), Expect = 7.0
Identities = 31/149 (20%), Positives = 66/149 (44%), Gaps = 11/149 (7%)
Query: 49 AELEAQLVQAEQRNRDLQA----DNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQT 104
AELE +L++ ++ R L+ +++++ E K+ Q+ + KQ+ LE L +
Sbjct: 721 AELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKK 780
Query: 105 RAIKEQLHKYVRELEQ----ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEK 160
++ K + L+Q LE R S + ++ + E L++++ E+
Sbjct: 781 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEE 840
Query: 161 ESLLVSVQRLKDEARDLRQELAVRERQQE 189
+ V++L ++EL + Q E
Sbjct: 841 ---TIKVRQLDSALEICKEELVLHLNQLE 866
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 50.8 bits (120), Expect = 2e-06
Identities = 60/285 (21%), Positives = 109/285 (38%), Gaps = 27/285 (9%)
Query: 13 KEETAYWKELSLK-YKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
K+E E LK YK+ + + E + ++LEA+ EQ +DLQ Q
Sbjct: 700 KQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQ- 758
Query: 72 LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQ----TRAIKEQLHKYVRELEQANDDLER 127
L ++E +L Q + VS DL + +IK++L K E + D E
Sbjct: 759 LNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFET 818
Query: 128 AKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
+ T + E+ R+ + L+ EKE+L+ + +KD+ + L + +
Sbjct: 819 LSQETKIQHEELNNRIQTTVTE---LQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSE 875
Query: 188 QEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGFGTSPLTPS 247
E + ++ LD EK ++ L + ENT K +
Sbjct: 876 FEKENQKGKAA-ILDLEKTCKELKHQLQVQ-------MENTLKEQKELKKSLEKEK---- 923
Query: 248 ARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVN 292
L ++ +++ +L +N K + + GN+N
Sbjct: 924 ------EASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNIN 962
Score = 47.8 bits (112), Expect = 1e-05
Identities = 50/224 (22%), Positives = 94/224 (41%), Gaps = 32/224 (14%)
Query: 8 DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA 67
+ + L EE K S+K + ++A+ L++ + EL+ + ++ EQ R+ Q
Sbjct: 1139 EITKLNEELKSHKLESIKEITNLKDAKQLLIQQK---LELQGKADSLKAAVEQEKRNQQI 1195
Query: 68 DNQRLKYEVEALKE---------------------KLEHQYAQSYKQVSVLEDDLSQTRA 106
++K E E LK+ K E A+ Q++ L ++L +
Sbjct: 1196 LKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKK 1255
Query: 107 IKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVS 166
+ + V ELE+ DDL ++++ + +ER E E+++ ++ ++
Sbjct: 1256 EWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLE 1315
Query: 167 VQRLKDEARDLRQELAVRERQ-------QEVTRKSAPSSPTLDC 203
+QR D QEL RE Q Q + RK A + +C
Sbjct: 1316 LQRKLDNTTAAVQELG-RENQSLQIKHTQALNRKWAEDNEVQNC 1358
Score = 47.4 bits (111), Expect = 2e-05
Identities = 54/218 (24%), Positives = 103/218 (47%), Gaps = 38/218 (17%)
Query: 12 LKEETAYWKELSL---KYKQSFQEAR----DELVEFQEGSRELEAELEAQLVQAEQRNRD 64
LKE+ EL K KQ QE + + +E +LE L Q+ +Q+ ++
Sbjct: 469 LKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLR-QIGDKDQKIQN 527
Query: 65 LQADNQRLKYEVEALKEKLEHQYA-------------QSYKQVSVLEDDLSQ-TRAIKEQ 110
L+A Q+ K + L+++ E YA Q ++ L++ ++Q T +K Q
Sbjct: 528 LEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQ 587
Query: 111 LHKYVRELEQANDDLE------RAKRATIVSLE----DFEQRLNQAIERNAFLESELDEK 160
+ + E +D ++ RA + ++SLE + +LN++ E+ + L+ ++ K
Sbjct: 588 SESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAK 647
Query: 161 ESLLVSVQRLKDEAR-DLRQEL-----AVRERQQEVTR 192
LL+S + K R DL+ L A++++QQE+ +
Sbjct: 648 TELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNK 685
Score = 47.0 bits (110), Expect = 3e-05
Identities = 52/184 (28%), Positives = 89/184 (48%), Gaps = 18/184 (9%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEA---QLVQAEQRNRDLQAD 68
LK + E +LK ++ E + L + +E S +L+ EL + QL+QA+ + + +
Sbjct: 897 LKHQLQVQMENTLKEQK---ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKE 953
Query: 69 NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQL-HKYVRELEQANDDLER 127
Q+L+ + LK+ E Q KQ+ L+ +L K +L +K ++L QA +L
Sbjct: 954 EQQLQGNINELKQSSE----QKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAA 1009
Query: 128 AKRATIVSLEDFEQRLNQAIERNAFLESELDEKES-LLVSVQRLK--DEARDLRQELAVR 184
K V ++E ++ E L+S+ +ES LL + Q LK +E L QE +
Sbjct: 1010 EKEKISVLQNNYE----KSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLIS 1065
Query: 185 ERQQ 188
R Q
Sbjct: 1066 NRNQ 1069
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/181 (22%), Positives = 87/181 (48%), Gaps = 24/181 (13%)
Query: 41 QEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEK---LEHQYAQSYKQVSVL 97
Q+ +EL ++ QL Q + +D Q +L+ ++ KEK LE + + Q+ L
Sbjct: 677 QDKQQELN-KITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKL 735
Query: 98 EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESEL 157
E D + +A KEQ + +++ Q N DLE RAT +S + LE E
Sbjct: 736 EADSLEVKASKEQALQDLQQQRQLNTDLE--LRATELSKQ---------------LEMEK 778
Query: 158 DEKESLLVSVQRLKDEARDLRQELAVRERQQEVTR---KSAPSSPTLDCEKMDSAVQASL 214
+ S + +Q+ + ++Q+L +E ++++ + ++ + E++++ +Q ++
Sbjct: 779 EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTV 838
Query: 215 S 215
+
Sbjct: 839 T 839
Score = 38.9 bits (89), Expect = 0.007
Identities = 45/208 (21%), Positives = 87/208 (41%), Gaps = 26/208 (12%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
+ L ++ E LK +Q + + ++ E + ++A L + + +Q L A
Sbjct: 298 NELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASE 357
Query: 70 -----------------QRLKYEVEALKEKLEH---QYAQSYKQVSVLEDDLSQTRAIKE 109
Q+LK E+ ++ K +H ++ Q +Q E Q ++
Sbjct: 358 TSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEIN 417
Query: 110 QLHKYV----RELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLV 165
QLH + R+L +A+ L+ ++ + L D EQ++ + + LE +L EK +
Sbjct: 418 QLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNST 477
Query: 166 SVQRLKDEARDLRQELAVRERQQEVTRK 193
+Q D+ + QE + QQ T K
Sbjct: 478 ELQHQLDKTKQQHQE--QQALQQSTTAK 503
Score = 37.7 bits (86), Expect = 0.015
Identities = 38/183 (20%), Positives = 81/183 (44%), Gaps = 34/183 (18%)
Query: 31 QEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQS 90
Q+ + EL+ Q E A L+ +LVQ + ++ + +R +++ +KL+ QYA S
Sbjct: 208 QDLKTELL--QRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASS 265
Query: 91 YKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERN 150
+S L +L++ +++ YV+EL++ + +N+ ++N
Sbjct: 266 EATISQLRSELAKG---PQEVAVYVQELQK------------------LKSSVNELTQKN 304
Query: 151 AFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAV 210
L L +KE ++ +E ++ + Q++ LDC+++ S +
Sbjct: 305 QTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKD-----------LDCQQLQSRL 353
Query: 211 QAS 213
AS
Sbjct: 354 SAS 356
Score = 36.6 bits (83), Expect = 0.034
Identities = 39/145 (26%), Positives = 70/145 (48%), Gaps = 25/145 (17%)
Query: 60 QRNRDLQADNQRLKYEVEALKEKLEHQYA---QSYKQVSVLEDDLSQTRAIKEQLHKYVR 116
Q +DLQA + K+ E LK++LE Q K ++ D ++ +++++QL
Sbjct: 90 QEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLE---- 145
Query: 117 ELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVS----VQRLKD 172
E + N ++++ K + FEQ+ Q A ++S+ DE+ SL + V RL +
Sbjct: 146 EAQTENFNIKQMK-------DLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTE 198
Query: 173 E-------ARDLRQELAVRERQQEV 190
E +DL+ EL R ++V
Sbjct: 199 ELNKEATVIQDLKTELLQRPGIEDV 223
Score = 33.9 bits (76), Expect = 0.22
Identities = 35/193 (18%), Positives = 86/193 (44%), Gaps = 29/193 (15%)
Query: 34 RDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEA-----------LKEK 82
+D+L + + + ++E E + + + DL+ + LK++++ LK+
Sbjct: 859 KDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKS 918
Query: 83 LEHQYAQSY----------KQVSVLEDDLSQTRAIKEQLHKYVRELEQANDD-------L 125
LE + S+ +Q+ ++ L Q ++QL + EL+Q+++ L
Sbjct: 919 LEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEAL 978
Query: 126 ERAKRATIVSLEDFEQRLNQAIERNA-FLESELDEKESLLVSVQRLKDEARDLRQELAVR 184
+ + ++ + E +L Q + + A L +E ++ L + ++ ++ + L+ + R
Sbjct: 979 QGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGR 1038
Query: 185 ERQQEVTRKSAPS 197
E + TR+ S
Sbjct: 1039 ESELLATRQDLKS 1051
Score = 32.3 bits (72), Expect = 0.64
Identities = 40/183 (21%), Positives = 78/183 (42%), Gaps = 20/183 (10%)
Query: 23 SLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA---DNQRLKYEVEAL 79
S+K K + QE ++++ ++ E + +Q E+ N +Q + Q++K E EAL
Sbjct: 797 SIKQKLTKQEEEKQILK-----QDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEAL 851
Query: 80 -------KEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
K+KL S E + + +A L K +EL+ L+ T
Sbjct: 852 MTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKH---QLQVQMENT 908
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELA--VRERQQEV 190
+ ++ ++ L + E + L+ EL+ + L+ Q + Q+L + E +Q
Sbjct: 909 LKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSS 968
Query: 191 TRK 193
+K
Sbjct: 969 EQK 971
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 50.8 bits (120), Expect = 2e-06
Identities = 46/204 (22%), Positives = 91/204 (44%), Gaps = 19/204 (9%)
Query: 29 SFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYA 88
+ Q+ EL ++ ++E +A+L L Q EQ ++ L+ ++L +LK+K +
Sbjct: 513 TIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLS---SSLKQKEQQLKE 569
Query: 89 QSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRL----- 143
+ KQ + +D Q E+ +RE + A LE ++ LE +Q+L
Sbjct: 570 VAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANE 629
Query: 144 ---------NQAIERNAFLESELDEKESLLVSVQRLKDEARD--LRQELAVRERQQEVTR 192
QA A L +++E ++ + + ++ + EA+ EL +R QQ+ T
Sbjct: 630 ARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATE 689
Query: 193 KSAPSSPTLDCEKMDSAVQASLSL 216
K + ++ A++ SL +
Sbjct: 690 KERVAQEKDQLQEQLQALKESLKV 713
Score = 43.9 bits (102), Expect = 2e-04
Identities = 43/188 (22%), Positives = 80/188 (42%), Gaps = 9/188 (4%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
+EE L + S E ++ S+ A L AQ+ L A Q+
Sbjct: 458 EEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQ 517
Query: 73 KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
E+ LK++ + + AQ + + E R EQL +++ EQ ++ + AT
Sbjct: 518 DQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEAT 577
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTR 192
+D Q+L A E E+ L E+++ L ++ L+ E +L + ++Q +V
Sbjct: 578 ---RQDHAQQLATAAEER---EASLRERDAALKQLEALEKEK---AAKLEILQQQLQVAN 628
Query: 193 KSAPSSPT 200
++ S+ T
Sbjct: 629 EARDSAQT 636
Score = 42.4 bits (98), Expect = 6e-04
Identities = 43/175 (24%), Positives = 81/175 (46%), Gaps = 11/175 (6%)
Query: 20 KELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEAL 79
++LS KQ Q+ + E+ E QE +R+ A+ A AE+R L+ + LK ++EAL
Sbjct: 554 EQLSSSLKQKEQQLK-EVAEKQEATRQDHAQQLA--TAAEEREASLRERDAALK-QLEAL 609
Query: 80 -KEK------LEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
KEK L+ Q + + + ++Q + K +L + V EL+ + + +
Sbjct: 610 EKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEA 669
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ 187
+ + E +L ++ E EK+ L +Q LK+ + + L +R+
Sbjct: 670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR 724
Score = 41.6 bits (96), Expect = 0.001
Identities = 57/220 (25%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 6 IPDFSSLKEETAYWKELSLKYKQSFQEARDELV--------EFQEGSRELEAELEAQLVQ 57
+ +L++E A E+ + Q EARD E E SR++E EL+A +
Sbjct: 603 LKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVE-ELQACVET 661
Query: 58 AEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDL-SQTRAIKEQLHKYVR 116
A Q + QA L+ ++ + E Q A ++V+ +D L Q +A+KE L
Sbjct: 662 ARQEQHEAQAQVAELELQLRS-----EQQKATEKERVAQEKDQLQEQLQALKESLKVTKG 716
Query: 117 ELEQ----ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKD 172
LE+ A D LE +R + + Q LE E ++ L +Q+L
Sbjct: 717 SLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQL-G 775
Query: 173 EARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQA 212
EA E+ RE + + + S +CE++ V A
Sbjct: 776 EAHQAETEVLRRELAEAMAAQHTAES---ECEQLVKEVAA 812
Score = 41.2 bits (95), Expect = 0.001
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 44/245 (17%)
Query: 12 LKEETAYWKELSLKYKQSFQE----ARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA 67
L+E+ KE K S +E A D L E Q EL+AE + + Q ++ ++L+
Sbjct: 700 LQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEE 759
Query: 68 DNQRLK--------------YEVEALKEKLEHQYAQSYKQVSVLE-------------DD 100
+ K E E L+ +L A + S E +D
Sbjct: 760 ERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYED 819
Query: 101 LSQTRA-----IKEQLHKYVRELEQANDDLERAKR--ATIVSLEDFE--QRLNQAIERNA 151
Q A +EQL E E+A +L+ AK A I S + + ++ N+ E +A
Sbjct: 820 SQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHA 879
Query: 152 FLESELDEKESLLVSVQRLKDEARDLRQELAVRERQ----QEVTRKSAPSSPTLDCEKMD 207
L L + + V Q+L D+ L++++A ++ + + RK+ T E +
Sbjct: 880 NLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVK 939
Query: 208 SAVQA 212
+A
Sbjct: 940 EPARA 944
Score = 40.4 bits (93), Expect = 0.002
Identities = 54/197 (27%), Positives = 92/197 (46%), Gaps = 24/197 (12%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE--------AELEAQLVQAEQRNRD 64
+E+ KE K +Q QEA++++ + S EL+ AEL A L +A Q+ ++
Sbjct: 832 QEQLMTLKEECEKARQELQEAKEKVAGIESHS-ELQISRQQNELAELHANLARALQQVQE 890
Query: 65 LQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDL-----SQTRAIKEQLHKYVRELE 119
+ Q+L ++ L+EK+ A + K+V+ LE + Q A +E + + R +
Sbjct: 891 KEVRAQKLADDLSTLQEKM----AATSKEVARLETLVRKAGEQQETASRELVKEPARAGD 946
Query: 120 QANDDLERAKRATIVSLEDFEQRLNQAIERNA-FLESELDEKESLLVSVQRLKDEARDLR 178
+ + LE + S Q QA+ER A + +EL+ + L+ Q + E R +
Sbjct: 947 RQPEWLEEQQGRQFCS----TQAALQAMEREAEQMGNELERLRAALMESQGQQQEERG-Q 1001
Query: 179 QELAVRERQQEVTRKSA 195
QE V QE R A
Sbjct: 1002 QEREVARLTQERGRAQA 1018
Score = 39.7 bits (91), Expect = 0.004
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 10/137 (7%)
Query: 34 RDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKY------EVEALKEKLEHQY 87
RDEL +R+L E +AQ+ +QR L N++ E+E L++K E
Sbjct: 230 RDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLT 289
Query: 88 AQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAI 147
+ ++ + +D + K Q+ + + +L + N DL R L+ + LN+
Sbjct: 290 MRLHETLKQCQD----LKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 148 ERNAFLESELDEKESLL 164
E ++ E EK++ L
Sbjct: 346 EEHSKATQEWLEKQAQL 362
Score = 39.7 bits (91), Expect = 0.004
Identities = 51/191 (26%), Positives = 89/191 (46%), Gaps = 28/191 (14%)
Query: 21 ELSLKYKQ---SFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR------DLQADNQR 71
ELS K ++ + AR E E Q ELE +L ++ +A ++ R LQ Q
Sbjct: 647 ELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQA 706
Query: 72 LKYEVEALKEKLEHQYAQSY----KQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLER 127
LK ++ K LE + ++ +Q + + ++TR++ EQ + +ELE+ ER
Sbjct: 707 LKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEE-----ER 761
Query: 128 AKRATIVSLEDFEQRLNQAIERNAFLESELDEKE--SLLVSVQRLKDEARDLRQELAV-R 184
A R + E RL Q E + E+E+ +E + + + E L +E+A R
Sbjct: 762 AGR------KGLEARLQQLGEAHQ-AETEVLRRELAEAMAAQHTAESECEQLVKEVAAWR 814
Query: 185 ERQQEVTRKSA 195
ER ++ ++ A
Sbjct: 815 ERYEDSQQEEA 825
Score = 39.7 bits (91), Expect = 0.004
Identities = 70/317 (22%), Positives = 138/317 (43%), Gaps = 37/317 (11%)
Query: 13 KEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRL 72
+E+T +ELS K S Q ++ + ++L+A ++AQ +++Q + LQA L
Sbjct: 1545 REQTKQVEELSKKLADSDQASKVQ-------QQKLKA-VQAQGGESQQEAQRLQAQLNEL 1596
Query: 73 KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
+ ++ ++ EH Q K + + Q + ++EQL + + +L++ N +L RA+
Sbjct: 1597 QAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQL-RSLEQLQKENKEL-RAE--- 1651
Query: 133 IVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTR 192
+RL +++ E ++ + + L + R L ++A ++Q
Sbjct: 1652 -------AERLGHELQQAGLKTKEAEQ------TCRHLTAQVRSLEAQVAHADQQLRDLG 1698
Query: 193 KSAPSSPTLDCEKMDSAVQASLSLPATPVG--KGTENTFPS--PKAIPNGFGTSPLTPSA 248
K ++ L + + Q LS+ + + +GT + S P+ P+G P P++
Sbjct: 1699 KFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSV-PGEPAS 1757
Query: 249 RISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYISGNVNCGVLNGNGTKFSRSGH 308
IS L KV +LES L A+ QA +S + + + +G T+ +R
Sbjct: 1758 PISQ-----RLPPKVESLES-LYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRSARRRT 1811
Query: 309 TSFFDKGAVNGFDPAPP 325
T + D P
Sbjct: 1812 TQIINITMTKKLDVEEP 1828
Score = 37.4 bits (85), Expect = 0.020
Identities = 32/152 (21%), Positives = 67/152 (44%), Gaps = 10/152 (6%)
Query: 38 VEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVL 97
VE + + EL A AE R ++Q + Q E+E + K E + ++
Sbjct: 1467 VELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1526
Query: 98 EDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESEL 157
+++ + A EQL + RE + ++L + L D +Q ++ ++++
Sbjct: 1527 QEERQKLTAQVEQLEVFQREQTKQVEELSK-------KLADSDQASKVQQQKLKAVQAQG 1579
Query: 158 DEKESLLVSVQRLKDEARDLRQELAVRERQQE 189
E + QRL+ + +L+ +L+ +E+ E
Sbjct: 1580 GESQQ---EAQRLQAQLNELQAQLSQKEQAAE 1608
Score = 37.0 bits (84), Expect = 0.026
Identities = 50/207 (24%), Positives = 89/207 (42%), Gaps = 21/207 (10%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADN 69
SSL+EE + L+ + +E + ++ E S++LE L +L+QAE + +A
Sbjct: 1228 SSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERL--RLLQAETASNSARAAE 1285
Query: 70 QR--LKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVREL---EQANDD 124
+ L+ EV++L+E+ E Q S L + + ++L + + EQA
Sbjct: 1286 RSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALST 1345
Query: 125 LE---RAKRATIVSLEDFEQRLNQAIERNAFLE----SELDEKESL-------LVSVQRL 170
L+ + +A + L + Q A E EL++ + L+ QR
Sbjct: 1346 LQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRE 1405
Query: 171 KDEARDLRQELAVRERQQEVTRKSAPS 197
E LRQ++A +ER + R S
Sbjct: 1406 LGELIPLRQKVAEQERTAQQLRAEKAS 1432
Score = 32.0 bits (71), Expect = 0.83
Identities = 39/165 (23%), Positives = 74/165 (44%), Gaps = 28/165 (16%)
Query: 39 EFQEGSRELE---AELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVS 95
E Q +RELE A+ E V+ + + Q + Q+L +VE L E + + + +++S
Sbjct: 1497 EAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQL-EVFQREQTKQVEELS 1555
Query: 96 VLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLES 155
D Q +++Q K V+ Q + + A+R + +LN+ L++
Sbjct: 1556 KKLADSDQASKVQQQKLKAVQA--QGGESQQEAQR--------LQAQLNE-------LQA 1598
Query: 156 ELDEKESLL----VSVQRLK---DEARDLRQELAVRERQQEVTRK 193
+L +KE + +++ K D + QEL + R E +K
Sbjct: 1599 QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQK 1643
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/189 (26%), Positives = 96/189 (50%), Gaps = 22/189 (11%)
Query: 24 LKYKQSFQEARDELV-EFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEK 82
+K S Q RD +V ++Q+ LE + +++ +Q ++ A+N +LK E+ L+
Sbjct: 2463 VKSMSSLQNDRDRIVGDYQQ----LEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSH 2518
Query: 83 LEHQYAQSYK---QVSVLEDDLSQTRAIKEQLHKYVRELE-QANDDLERAKRATIVSLED 138
++ +++ K ++ +DL+Q IK+ K + E++ Q N +LE L++
Sbjct: 2519 MDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKE 2578
Query: 139 FEQRLNQAIER--NAFLESELD---EKESLLVSVQRLKDEARDLRQE-------LAVRER 186
E+ N+ + R NA E + D E ESL VS+ +L + L++E ++ +
Sbjct: 2579 SEE-ANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVK 2637
Query: 187 QQEVTRKSA 195
++EV R SA
Sbjct: 2638 EEEVHRLSA 2646
Score = 47.0 bits (110), Expect = 3e-05
Identities = 64/282 (22%), Positives = 119/282 (42%), Gaps = 46/282 (16%)
Query: 10 SSLKEETAYW----KELSLKYK---QSFQEARDELVEFQ---EGSRELEAELEAQLVQAE 59
SS E+ W KEL +Y+ QS++ +E Q E R+ + EL +L E
Sbjct: 1595 SSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTE 1654
Query: 60 QRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELE 119
++ + Q + E+E +KEK+ ++A+S KQ +LE ++E+ + E+
Sbjct: 1655 ANKKETEKQLQEAEQEMEEMKEKM-RKFAKS-KQQKILE--------LEEENDRLRAEVH 1704
Query: 120 QANDDLERAKRATIVSLEDFEQRLNQAIERNAFL----ESELDEKESLLVSVQRLKDEAR 175
A D + + S ++ L + L +S + EK+SL VQ LK +
Sbjct: 1705 PAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIE 1764
Query: 176 DLRQELA------VRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTF 229
+ A + Q VT + S P ++ Q SLS+ P
Sbjct: 1765 GNVSKQANLEATEKHDNQTNVTEEGTQSIPG------ETEEQDSLSMSTRPT-------- 1810
Query: 230 PSPKAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLA 271
+++P+ +P S S+ + + + L+++ L+ ++A
Sbjct: 1811 -CSESVPSAKSANPAV-SKDFSSHDEINNYLQQIDQLKERIA 1850
Score = 43.5 bits (101), Expect = 3e-04
Identities = 54/262 (20%), Positives = 120/262 (45%), Gaps = 35/262 (13%)
Query: 21 ELSLKYKQSFQEARDELVEFQE---GSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVE 77
++ + +Q + + +L E +E G ++ L+ +L AEQRN+ L Q+++ E
Sbjct: 245 DVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHN 304
Query: 78 ALKEKLEHQYAQSYKQVSVLEDDLSQTRA----IKEQLHKYVRELEQANDDLERAKRATI 133
L+ +E + +S + +E ++++ + ++E++H + + EQA
Sbjct: 305 TLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQ---------- 354
Query: 134 VSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLK-------DEARDLRQELAVRER 186
+ + E R + +++ ++E++EK S ++S+Q+ D +D +L +
Sbjct: 355 -AQAELESRYSALEQKH---KAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKN 410
Query: 187 QQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFPSPKAIPNGF--GTSPL 244
+Q V +SA + L+ + + + S L P+ ++ S + P+ + GT +
Sbjct: 411 EQAV--QSAQTIQQLEDQLQQKSKEISQFLNRLPL---QQHETASQTSFPDVYNEGTQAV 465
Query: 245 TPSARISALNIVGDLLRKVGAL 266
T S V +L + GAL
Sbjct: 466 TEENIASLQKRVVELENEKGAL 487
Score = 40.0 bits (92), Expect = 0.003
Identities = 47/186 (25%), Positives = 84/186 (45%), Gaps = 35/186 (18%)
Query: 29 SFQEARDELVEFQEGSRELEAELEAQLVQAEQRNR-----------DLQADNQRLKYEVE 77
+ QE L+E E + + +AELE++ EQ+++ LQ Q L+ +
Sbjct: 337 NLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACD 396
Query: 78 ALKEK-------LEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKR 130
ALK++ Q QS + + LED L Q +++ +++ L L++ +
Sbjct: 397 ALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQK---SKEISQFLNRL-----PLQQHET 448
Query: 131 ATIVSLEDFEQRLNQAI--ERNAFLESEL----DEKESLLVS---VQRLKDEARDLRQEL 181
A+ S D QA+ E A L+ + +EK +LL+S ++ LK E L ++
Sbjct: 449 ASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQI 508
Query: 182 AVRERQ 187
+ E Q
Sbjct: 509 TLLEAQ 514
Score = 40.0 bits (92), Expect = 0.003
Identities = 43/183 (23%), Positives = 92/183 (50%), Gaps = 10/183 (5%)
Query: 20 KELSLKYKQSFQEARDELVEFQEGSRELEAELEA-QLVQAEQRNRDLQADNQRLKYEVEA 78
+EL + +Q ++ + + + +QE LE ++A + VQ E + +DL+ + L VE
Sbjct: 2011 QELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQ-KDLEITKENLAQAVEH 2069
Query: 79 LKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRATIVSLED 138
++K + + A S+K +L+D S+ + K +EL+ + E K ED
Sbjct: 2070 -RKKAQAELA-SFK--VLLDDTQSEAARVLADNLKLKKELQ---SNKESVKSQMKQKDED 2122
Query: 139 FEQRLNQAIERNAFLESELDEK-ESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPS 197
E+RL QA E++ + + EK ++L L++ +++ L ++++ + +++ S
Sbjct: 2123 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2182
Query: 198 SPT 200
+ T
Sbjct: 2183 TVT 2185
Score = 38.1 bits (87), Expect = 0.012
Identities = 40/166 (24%), Positives = 76/166 (45%), Gaps = 30/166 (18%)
Query: 36 ELVEFQ-EGSRELE---AELEAQLVQAEQRNRDL-------QADNQRLKYEVEALKEKLE 84
+L+E Q + ++ELE A+LE +L ++E+ N DL Q + Q L E+E+LK +
Sbjct: 2553 QLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSIS 2612
Query: 85 HQYAQS------------YKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAKRAT 132
Q + Q+ V E+++ + A+ K + ELE+ +++
Sbjct: 2613 QLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKK 2672
Query: 133 IVSLED-FEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
+ +ED ++ L + +E + E +R+ + ARDL
Sbjct: 2673 VGEIEDKLKKELKHLHHDAGIMRNETETAE------ERVAELARDL 2712
Score = 37.7 bits (86), Expect = 0.015
Identities = 47/201 (23%), Positives = 93/201 (46%), Gaps = 18/201 (8%)
Query: 4 EDIPDFSSLKE-ETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRN 62
E++ S KE E +L L+ K+ + + + E + E+ + ++VQ +
Sbjct: 862 EELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEK 921
Query: 63 RDLQADNQRLKYEV-------EALKEKLE--HQYAQSYKQVSVLEDDLSQTRAI-KEQLH 112
L + + LK ++ EA KE++E ++ + KQ D++S I KE+L
Sbjct: 922 FSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNY---DEMSPAGQISKEELQ 978
Query: 113 KYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQR--- 169
L++ N+ +R +A +++ ++ QR+++ E A L+ E +KE L +R
Sbjct: 979 HEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDE-SKKEIPLSETERGEV 1037
Query: 170 LKDEARDLRQELAVRERQQEV 190
+D+ E V + QE+
Sbjct: 1038 EEDKENKEYSEKCVTSKCQEI 1058
Score = 37.4 bits (85), Expect = 0.020
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 6/182 (3%)
Query: 8 DFSSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQA 67
+ + L+ E K+ S ++ +++ + R+ EA+++ EQ DLQA
Sbjct: 2306 ELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQA 2365
Query: 68 DNQ---RLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQ--TRAIKEQLHKYVRELEQAN 122
+ RL E+ ++K+ + + + V +L Q + IKE L + + E+ N
Sbjct: 2366 SRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKE-LENLLSQEEEEN 2424
Query: 123 DDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQELA 182
LE + + + L + N +++LD + S+Q +D Q+L
Sbjct: 2425 IVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLE 2484
Query: 183 VR 184
R
Sbjct: 2485 ER 2486
Score = 35.8 bits (81), Expect = 0.058
Identities = 41/187 (21%), Positives = 81/187 (43%), Gaps = 16/187 (8%)
Query: 42 EGSRELEAELEAQLVQAEQR-------NRDLQADNQRLKYEVEALKEKLEHQYAQSYKQV 94
E + E AEL LV+ EQ+ N+ L A Q + +L+ +H + +
Sbjct: 2699 ETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELK 2758
Query: 95 SVLEDDLSQTRAIKEQ-LHKYVRE--LEQANDDLERAKRATIVSLEDFEQRL----NQAI 147
+ L + +KEQ L R+ L + + + ++ LE Q+L Q +
Sbjct: 2759 RKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLL 2818
Query: 148 ERNAFLESELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSA--PSSPTLDCEK 205
++ LE ++ +S ++ L++E L EL + +E ++SA PS+ + +
Sbjct: 2819 HLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQS 2878
Query: 206 MDSAVQA 212
+ A+ +
Sbjct: 2879 LKKAMSS 2885
Score = 33.5 bits (75), Expect = 0.29
Identities = 56/247 (22%), Positives = 99/247 (40%), Gaps = 42/247 (17%)
Query: 11 SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQ------------LVQA 58
+LKE + +ELSL AR + + ++E+++ AQ L+Q
Sbjct: 1495 ALKENKSLQEELSL--------ARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQE 1546
Query: 59 EQRNRDLQAD-----NQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHK 113
E+ + D NQ L E+LK LE K V +E S A + +
Sbjct: 1547 ERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQE 1606
Query: 114 YVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDE 173
+EL++ + L L+ +E N+A +E+ EK+ L ++ +
Sbjct: 1607 KHKELQKEYEIL----------LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEAN 1656
Query: 174 ARDLRQELAVRERQ----QEVTRKSAPS--SPTLDCEKMDSAVQASLSLPATPVGKGTEN 227
++ ++L E++ +E RK A S L+ E+ + ++A + PA K
Sbjct: 1657 KKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVH-PAGDTAKECME 1715
Query: 228 TFPSPKA 234
T S A
Sbjct: 1716 TLLSSNA 1722
Score = 32.3 bits (72), Expect = 0.64
Identities = 45/236 (19%), Positives = 98/236 (41%), Gaps = 39/236 (16%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEA---RDELVEFQEGS--------RELEAELEAQLVQA 58
SSL+++ + + K+++ F +A ++E + +E + R++ +E +
Sbjct: 2195 SSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINI 2254
Query: 59 EQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVREL 118
+ D Q + + EV+ ++ + ++ + +S LE+ + + +L K EL
Sbjct: 2255 SRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESEL 2314
Query: 119 EQANDDLE--------------------RAKRATI----VSLEDFEQRLNQAIERNAFLE 154
+ D L R + A I S E E L + E + L
Sbjct: 2315 KSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLH 2374
Query: 155 SELDEKESLLVSVQRLKDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAV 210
E++ KE ++S+ K+EA ++A+ E +Q+ ++ L E+ ++ V
Sbjct: 2375 EEINMKEQKIISLLSGKEEA----IQVAIAELRQQHDKEIKELENLLSQEEEENIV 2426
Score = 32.0 bits (71), Expect = 0.83
Identities = 39/179 (21%), Positives = 69/179 (38%), Gaps = 18/179 (10%)
Query: 27 KQSFQEARDELVEFQEGSRELEAE---LEAQLVQAEQRNRDLQADNQRLKYEVEALKEKL 83
K QE +D+ FQ EL E + +L Q + +R+K +
Sbjct: 2918 KAQLQEYQDKTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDK 2977
Query: 84 EHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQANDD--------LERAKRATIVS 135
+ Q + + L SQT+ +K Q + A+ D E + S
Sbjct: 2978 DQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDS 3037
Query: 136 LEDFEQRLNQAIERNAFLESELDEKESLLVSV----QRLKDEAR---DLRQELAVRERQ 187
L++ Q+ + + N+ L+EK +L + + Q L++ + DL AV E+Q
Sbjct: 3038 LKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQ 3096
Score = 31.2 bits (69), Expect = 1.4
Identities = 40/168 (23%), Positives = 74/168 (44%), Gaps = 36/168 (21%)
Query: 32 EARDELVEFQEGSRELEAELEAQLVQAEQRNRDL-----QADNQRLKYEVEALKEKLEHQ 86
EA L + + +EL++ E+ Q +Q++ DL QA+ + LK E + ++EKL+
Sbjct: 2090 EAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK-EKKNMQEKLDAL 2148
Query: 87 YAQSY-----------------KQVSVLEDDLSQTRAIKEQLHKYVRELEQANDDLERAK 129
+ K+V L+++L T QL + + + DD +R
Sbjct: 2149 RREKVHLEETIGEIQVTLNKKDKEVQQLQENLDST---VTQLAAFTKSMSSLQDDRDR-- 2203
Query: 130 RATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDL 177
I + +E++ + AI+ E E+ KE + LKD+ R +
Sbjct: 2204 --VIDEAKKWERKFSDAIQSK---EEEIRLKED---NCSVLKDQLRQM 2243
Score = 28.9 bits (63), Expect = 7.0
Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 13/72 (18%)
Query: 38 VEFQEGSRELEAELEAQLVQAEQRNRDLQAD------------NQRLKYEVEALKEKLEH 85
+E +E E E +L +Q+ E +NR +AD N+R E+ ++ LE+
Sbjct: 492 IELEELKAENE-KLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLEN 550
Query: 86 QYAQSYKQVSVL 97
++Q +K++SVL
Sbjct: 551 TFSQKHKELSVL 562
>gi|149363685 hypothetical protein LOC23379 [Homo sapiens]
Length = 2266
Score = 50.4 bits (119), Expect = 2e-06
Identities = 84/371 (22%), Positives = 148/371 (39%), Gaps = 74/371 (19%)
Query: 10 SSLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELE------AELEAQLVQAEQRNR 63
+SL++ + E + KQ + L E+Q+ EL+ + L Q+ + Q+
Sbjct: 24 ASLQQNLNEYVEALITLKQKIINTDNLLTEYQKKCDELQFARRENSNLHHQVEEMLQKIS 83
Query: 64 DLQADNQRL---KYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLHKYVRELEQ 120
LQ + L K E+E K L+ Y ++++ + ++++ ++ A K++L V++L++
Sbjct: 84 PLQKCQEELGSLKAELEEKKSSLK-LYQDTHQEYARVKEECLKSDAQKKKLEAKVKKLQE 142
Query: 121 ANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKDEARDLRQE 180
A + +DF+Q N+ LE E + + L + K+E
Sbjct: 143 A----------AVKQTQDFKQLRNE----KKILEKEFKKTQERLDEFSKQKNE------- 181
Query: 181 LAVRERQQEVTRKSAPSSPTLDCEKMDS-------AVQASLSLPATPVGKGTENTFPSP- 232
+E + T+ S+ S ++D K+ V + LP G+G+ P
Sbjct: 182 ---KELRHIGTQISSDSYGSIDKRKVKLLLKELWLCVNTTHRLP----GEGSRCVPEKPA 234
Query: 233 -----KAIPNGFGTSPLTPSARISALNIVGDLLRKVGALESKLAACRNFAKDQASRKSYI 287
+P GT P T + + N V L K+ + C+N K +S +
Sbjct: 235 KAITSSRVPGEDGTLPPTQGSPLRTSN-VQTCLTKLSMEIKEDFLCQNVEKQSSSGTNCS 293
Query: 288 SGNV-----NCGVL-----NGNGTKFSRSGHTSFFDKGAVNGFD----------PAPPPP 327
S +V N VL +G T+F H FFD+ D P P PP
Sbjct: 294 SDHVFNENGNLEVLVQSHRDGGSTEFV--DHDHFFDEDLQAAIDFFKLPPPLLSPVPSPP 351
Query: 328 GLGSSRPSSAP 338
+ S P S P
Sbjct: 352 PMSSPHPGSLP 362
>gi|109255239 centrosomal protein 63 isoform b [Homo sapiens]
Length = 541
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/294 (21%), Positives = 127/294 (43%), Gaps = 31/294 (10%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
++E +E++++YKQ ++ +EL + +L+ + + + +R+ +++ +R
Sbjct: 82 VEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHREDRSEIER 141
Query: 72 LKYEVEALKEK---LEHQYAQSYKQVSVLEDD----LSQTRAIKEQLHKYVRELEQA--- 121
L ++E ++K E Q +QVS LE Q+ I+ QL ++LE
Sbjct: 142 LTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELS 201
Query: 122 --------NDDLERAKR---ATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRL 170
+ LERA A + +E R+N + + + E +KE L ++L
Sbjct: 202 SQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKL 261
Query: 171 KDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFP 230
+ ++ ++EL + QE A + EK+ V+A+ + A + E +
Sbjct: 262 LEALQEEKRELKAALQSQENLIHEA----RIQKEKLQEKVKATNTQHAVEAIRPREESLA 317
Query: 231 SPKAIPNGFGTSPLTPSARISALNIVGDLLRK-----VGALESKLAACRNFAKD 279
K G G S +++ + DLL+ G+LES A C+ +++
Sbjct: 318 EKKYTSQGQGDLDSVLS-QLNFTHTSEDLLQAEVTCLEGSLESVSATCKQLSQE 370
>gi|22095367 centrosomal protein 63 isoform a [Homo sapiens]
Length = 703
Score = 50.4 bits (119), Expect = 2e-06
Identities = 63/294 (21%), Positives = 127/294 (43%), Gaps = 31/294 (10%)
Query: 12 LKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQR 71
++E +E++++YKQ ++ +EL + +L+ + + + +R+ +++ +R
Sbjct: 82 VEEHEKIKQEMTMEYKQELKKLHEELCILKRSYEKLQKKQMREFRGNTKNHREDRSEIER 141
Query: 72 LKYEVEALKEK---LEHQYAQSYKQVSVLEDD----LSQTRAIKEQLHKYVRELEQA--- 121
L ++E ++K E Q +QVS LE Q+ I+ QL ++LE
Sbjct: 142 LTAKIEEFRQKSLDWEKQRLIYQQQVSSLEAQRKALAEQSEIIQAQLVNRKQKLESVELS 201
Query: 122 --------NDDLERAKR---ATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRL 170
+ LERA A + +E R+N + + + E +KE L ++L
Sbjct: 202 SQSEIQHLSSKLERANDTICANELEIERLTMRVNDLVGTSMTVLQEQQQKEEKLRESEKL 261
Query: 171 KDEARDLRQELAVRERQQEVTRKSAPSSPTLDCEKMDSAVQASLSLPATPVGKGTENTFP 230
+ ++ ++EL + QE A + EK+ V+A+ + A + E +
Sbjct: 262 LEALQEEKRELKAALQSQENLIHEA----RIQKEKLQEKVKATNTQHAVEAIRPREESLA 317
Query: 231 SPKAIPNGFGTSPLTPSARISALNIVGDLLRK-----VGALESKLAACRNFAKD 279
K G G S +++ + DLL+ G+LES A C+ +++
Sbjct: 318 EKKYTSQGQGDLDSVLS-QLNFTHTSEDLLQAEVTCLEGSLESVSATCKQLSQE 370
Score = 34.3 bits (77), Expect = 0.17
Identities = 40/186 (21%), Positives = 77/186 (41%), Gaps = 27/186 (14%)
Query: 11 SLKEETAYWKELSLKYKQSFQEARDELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQ 70
SL+ +A K+LS Q E +EL + + E +AE++ Q Q + + +
Sbjct: 356 SLESVSATCKQLS----QELMEKYEELKRMEAHNNEYKAEIKKLKEQILQGEQSYSSALE 411
Query: 71 RLKYEVEALKEKLEHQ--------------YAQSYKQVSVLEDDLSQTRAIKEQLHKYVR 116
+K E+ L ++L + + ++ ED + + I +QL
Sbjct: 412 GMKMEISHLTQELHQRDITIASTKGSSSDMEKRLRAEMQKAEDKAVEHKEILDQLESLKL 471
Query: 117 ELEQAND-------DLERAKRATIVSL-EDFEQRLNQAIERNAFLESEL-DEKESLLVSV 167
E ++ L AK ++ L E++ + LN+ + N L+ +L + K L +S
Sbjct: 472 ENRHLSEMVMKLELGLHEAKEISLADLQENYIEALNKLVSENQQLQKDLMNTKSQLEIST 531
Query: 168 QRLKDE 173
Q K +
Sbjct: 532 QMCKKQ 537
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 50.4 bits (119), Expect = 2e-06
Identities = 44/188 (23%), Positives = 87/188 (46%), Gaps = 15/188 (7%)
Query: 22 LSLKYKQSFQEARD-ELVEFQEGSRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALK 80
L L+ K+SF + +L + E L E+ E + R + ++++ E L+
Sbjct: 497 LRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLR 556
Query: 81 EKLEHQYAQSYKQVSVLEDDLSQT----RAIKEQLHKYVRELEQANDDLERAKRATIVSL 136
+K + Q +V L+ D S T ++E L + R +E+ + ER R + +
Sbjct: 557 DK-DKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEI 615
Query: 137 EDFEQRLNQAIERNAFLESELDEKESLLVSVQR---------LKDEARDLRQELAVRERQ 187
E F + E+ L++EL EKES L+ ++ LK +++ E+A+ +++
Sbjct: 616 ESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKK 675
Query: 188 QEVTRKSA 195
+E ++ A
Sbjct: 676 EECSKLEA 683
Score = 39.7 bits (91), Expect = 0.004
Identities = 45/201 (22%), Positives = 90/201 (44%), Gaps = 23/201 (11%)
Query: 4 EDIPDFSSLKEETAYWKELSLKYKQSFQEARD-ELVEFQEGSRELEAELEAQ----LVQA 58
E++ S L+ E A K L Q+ E +D ++ + R+LE E++ ++
Sbjct: 358 EELHRRSQLQPEPAKTKAL-----QTVIEMKDTKIASLERNIRDLEDEIQMLKANGVLNT 412
Query: 59 EQRNRDLQ------ADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQTRAIKEQLH 112
E R +++ + ++ +K +++ LK++L + ++ + LE +Q K+ +
Sbjct: 413 EDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIE 472
Query: 113 KYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERNAFLESELDEKESLLVSVQRLKD 172
L + +RA I+ E RL E+ +FL + + + L L
Sbjct: 473 VLKESLTA------KEQRAAILQTEVDALRLRLE-EKESFLNKKTKQLQDLTEEKGTLAG 525
Query: 173 EARDLRQELAVRERQQEVTRK 193
E RD++ L V+ER+ V +K
Sbjct: 526 EIRDMKDMLEVKERKINVLQK 546
Score = 34.3 bits (77), Expect = 0.17
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 15/142 (10%)
Query: 44 SRELEAELEAQLVQAEQRNRDLQADNQRLKYEVEALKEKLEHQYAQSYKQVSVLEDDLSQ 103
+++LE + AQL++ +R D ADN + ++E L LE + E D ++
Sbjct: 771 NQQLEKKKNAQLLEEVRRREDSMADNSQ-HLQIEELMNALEK---------TRQELDATK 820
Query: 104 TRAIKEQLHKYVRELEQANDDLERAKRATIVSLEDFEQRLNQAIERN----AFLESELDE 159
R Q +E AN +ER K+ + LE ++ L AI A LE +
Sbjct: 821 ARLASTQQSLAEKEAHLANLRIERRKQLEEI-LEMKQEALLAAISEKDANIALLELSASK 879
Query: 160 KESLLVSVQRLKDEARDLRQEL 181
K+ V LK E L +L
Sbjct: 880 KKKTQEEVMALKREKDRLVHQL 901
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,347,018
Number of Sequences: 37866
Number of extensions: 659798
Number of successful extensions: 8517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 362
Number of HSP's successfully gapped in prelim test: 765
Number of HSP's that attempted gapping in prelim test: 4542
Number of HSP's gapped (non-prelim): 3398
length of query: 345
length of database: 18,247,518
effective HSP length: 103
effective length of query: 242
effective length of database: 14,347,320
effective search space: 3472051440
effective search space used: 3472051440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.