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Search of human proteins with 13491172
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13491172 periaxin isoform 1 [Homo sapiens]
(147 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13491172 periaxin isoform 1 [Homo sapiens] 287 2e-78
gi|116686120 periaxin isoform 2 [Homo sapiens] 249 6e-67
gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens] 105 2e-23
gi|55769541 AHNAK nucleoprotein isoform 2 [Homo sapiens] 52 2e-07
gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens] 51 3e-07
gi|116875765 tight junction protein 1 isoform b [Homo sapiens] 43 8e-05
gi|116875767 tight junction protein 1 isoform a [Homo sapiens] 43 8e-05
gi|45827729 scribble isoform b [Homo sapiens] 40 0.001
gi|45827731 scribble isoform a [Homo sapiens] 40 0.001
gi|10092691 tight junction protein 3 [Homo sapiens] 39 0.002
gi|112382257 InaD-like [Homo sapiens] 39 0.002
gi|148746189 multiple PDZ domain protein [Homo sapiens] 38 0.003
gi|95089461 discs large homolog 5 [Homo sapiens] 37 0.005
gi|42518065 tight junction protein 2 (zona occludens 2) isoform ... 35 0.023
gi|42518070 tight junction protein 2 (zona occludens 2) isoform ... 35 0.023
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 35 0.029
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 35 0.029
gi|157388993 synaptojanin 2 binding protein [Homo sapiens] 35 0.029
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 34 0.038
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 34 0.038
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 34 0.038
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 34 0.050
gi|119943108 synapse-associated protein 102 isoform b [Homo sapi... 33 0.066
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 32 0.19
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 32 0.19
gi|4759306 lin-7 homolog A [Homo sapiens] 32 0.19
gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo sa... 31 0.33
gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo sa... 31 0.33
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 31 0.42
gi|87196343 PDZ domain containing 2 [Homo sapiens] 31 0.42
>gi|13491172 periaxin isoform 1 [Homo sapiens]
Length = 147
Score = 287 bits (735), Expect = 2e-78
Identities = 147/147 (100%), Positives = 147/147 (100%)
Query: 1 MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ 60
MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ
Sbjct: 1 MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ 60
Query: 61 EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP 120
EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP
Sbjct: 61 EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP 120
Query: 121 RAKVAKLVRVLSPAPALDCPSDPVSAP 147
RAKVAKLVRVLSPAPALDCPSDPVSAP
Sbjct: 121 RAKVAKLVRVLSPAPALDCPSDPVSAP 147
>gi|116686120 periaxin isoform 2 [Homo sapiens]
Length = 1461
Score = 249 bits (636), Expect = 6e-67
Identities = 134/150 (89%), Positives = 137/150 (91%), Gaps = 8/150 (5%)
Query: 1 MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ 60
MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ
Sbjct: 1 MEARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQ 60
Query: 61 EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP 120
EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP
Sbjct: 61 EGDQLLSARVFFENFKYEDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGP 120
Query: 121 RAKVAKL-VRVLSPAP-------ALDCPSD 142
RAKVAKL ++ LSP AL P+D
Sbjct: 121 RAKVAKLNIQSLSPVKKKKMVPGALGVPAD 150
>gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]
Length = 5795
Score = 105 bits (261), Expect = 2e-23
Identities = 48/87 (55%), Positives = 67/87 (77%)
Query: 15 ELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFEN 74
E E+ ++TE + G SG +V GGG +GIFV+++ +DS AA+ +L+EGDQLLS VFFEN
Sbjct: 109 EATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTVFFEN 168
Query: 75 FKYEDALRLLQCAEPYKVSFCLKRTVP 101
KYEDAL++LQ +EPYKV F ++R +P
Sbjct: 169 IKYEDALKILQYSEPYKVQFKIRRQLP 195
>gi|55769541 AHNAK nucleoprotein isoform 2 [Homo sapiens]
Length = 149
Score = 51.6 bits (122), Expect = 2e-07
Identities = 36/123 (29%), Positives = 67/123 (54%), Gaps = 8/123 (6%)
Query: 18 EIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFENFKY 77
E+++ +G G+ +A +G+FV+E+ ++SPAAR+ ++EGDQ++ A ++F+N +
Sbjct: 9 ELLLPNWQGSGSHGLTIAQRD-DGVFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQS 67
Query: 78 EDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLVRVLSPAP-A 136
+ +LL + V L R GD + PG E+ + + V + +P P A
Sbjct: 68 GEVTQLLNTMGHHTVGLKLHR---KGDRSPEPGQTWTREV---FSSCSSEVVLNTPQPSA 121
Query: 137 LDC 139
L+C
Sbjct: 122 LEC 124
>gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]
Length = 5890
Score = 51.2 bits (121), Expect = 3e-07
Identities = 29/93 (31%), Positives = 54/93 (58%), Gaps = 4/93 (4%)
Query: 18 EIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFENFKY 77
E+++ +G G+ +A +G+FV+E+ ++SPAAR+ ++EGDQ++ A ++F+N +
Sbjct: 9 ELLLPNWQGSGSHGLTIAQRD-DGVFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQS 67
Query: 78 EDALRLLQCAEPYKVSFCLKRTVPTGDLALRPG 110
+ +LL + V L R GD + PG
Sbjct: 68 GEVTQLLNTMGHHTVGLKLHR---KGDRSPEPG 97
>gi|116875765 tight junction protein 1 isoform b [Homo sapiens]
Length = 1668
Score = 43.1 bits (100), Expect = 8e-05
Identities = 26/55 (47%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 31 GINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSA-RVFFENFKYEDALRLL 84
G+ +AGG GIFV + EDSPAA+ L+EGDQ+L V F N E+A+ L
Sbjct: 434 GLRLAGGNDVGIFVAGVLEDSPAAKE-GLEEGDQILRVNNVDFTNIIREEAVLFL 487
Score = 33.9 bits (76), Expect = 0.050
Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 42 IFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDALRLLQ 85
IFV+E+ +DS AAR ++QEGD +L EN DA L++
Sbjct: 206 IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIE 250
>gi|116875767 tight junction protein 1 isoform a [Homo sapiens]
Length = 1748
Score = 43.1 bits (100), Expect = 8e-05
Identities = 26/55 (47%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 31 GINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSA-RVFFENFKYEDALRLL 84
G+ +AGG GIFV + EDSPAA+ L+EGDQ+L V F N E+A+ L
Sbjct: 434 GLRLAGGNDVGIFVAGVLEDSPAAKE-GLEEGDQILRVNNVDFTNIIREEAVLFL 487
Score = 33.9 bits (76), Expect = 0.050
Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 42 IFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDALRLLQ 85
IFV+E+ +DS AAR ++QEGD +L EN DA L++
Sbjct: 206 IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIE 250
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 39.7 bits (91), Expect = 0.001
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 10 ELRRAELVEIIVETEAQTGVSGINVAGG--------GKEGIFVRELREDSPAARSLSLQE 61
E R E E+ + QTG GI++AGG EGIF+ + E+ PAAR+ ++
Sbjct: 718 EPARIEEEELTLTILRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARA-GVRV 776
Query: 62 GDQLLSAR-VFFENFKYEDALRLLQCA 87
GD+LL V + ++ +A+ L+ A
Sbjct: 777 GDKLLEVNGVALQGAEHHEAVEALRGA 803
Score = 35.0 bits (79), Expect = 0.023
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
Query: 31 GINVAGG--------GKEGIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDAL 81
G ++AGG G GIFV + E A R+ +LQ GD++LS V +++ A+
Sbjct: 873 GFSIAGGKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAV 932
Query: 82 RLLQCAEP 89
LL A P
Sbjct: 933 SLLTAASP 940
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 39.7 bits (91), Expect = 0.001
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 10 ELRRAELVEIIVETEAQTGVSGINVAGG--------GKEGIFVRELREDSPAARSLSLQE 61
E R E E+ + QTG GI++AGG EGIF+ + E+ PAAR+ ++
Sbjct: 718 EPARIEEEELTLTILRQTGGLGISIAGGKGSTPYKGDDEGIFISRVSEEGPAARA-GVRV 776
Query: 62 GDQLLSAR-VFFENFKYEDALRLLQCA 87
GD+LL V + ++ +A+ L+ A
Sbjct: 777 GDKLLEVNGVALQGAEHHEAVEALRGA 803
Score = 35.0 bits (79), Expect = 0.023
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 9/68 (13%)
Query: 31 GINVAGG--------GKEGIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDAL 81
G ++AGG G GIFV + E A R+ +LQ GD++LS V +++ A+
Sbjct: 873 GFSIAGGKGSTPYRAGDAGIFVSRIAEGGAAHRAGTLQVGDRVLSINGVDVTEARHDHAV 932
Query: 82 RLLQCAEP 89
LL A P
Sbjct: 933 SLLTAASP 940
>gi|10092691 tight junction protein 3 [Homo sapiens]
Length = 952
Score = 38.9 bits (89), Expect = 0.002
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 14/115 (12%)
Query: 42 IFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDALRLLQCAEPYKVSFCLKR-- 98
IF++ + + AAR LQEGD +L V +N D RL++ +E K+S + R
Sbjct: 233 IFIKHITDSGLAARHRGLQEGDLILQINGVSSQNLSLNDTRRLIEKSEG-KLSLLVLRDR 291
Query: 99 -----TVP-----TGDLALRPGTVSGYEIKGPRAKVAKLVRVLSPAPALDCPSDP 143
+P + L G E+ P A ++ L LS AP P P
Sbjct: 292 GQFLVNIPPAVSDSDSSPLEEGVTMADEMSSPPADISDLASELSQAPPSHIPPPP 346
Score = 38.9 bits (89), Expect = 0.002
Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 31 GINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDALRLL 84
G+ +AGG GIFV ++ SP A +QEGDQ+L V F+N E+A++ L
Sbjct: 426 GLRLAGGNDVGIFVSGVQAGSP-ADGQGIQEGDQILQVNDVPFQNLTREEAVQFL 479
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 38.5 bits (88), Expect = 0.002
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 13/81 (16%)
Query: 20 IVETEAQTGVS-GINVAGG---------GKE--GIFVRELREDSPAARSLSLQEGDQLLS 67
IVE + VS GI++ GG G+E GIF++++ EDSPA ++ +L+ GD++L
Sbjct: 1068 IVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILE 1127
Query: 68 -ARVFFENFKYEDALRLLQCA 87
+ V +N + +A+ ++ A
Sbjct: 1128 VSGVDLQNASHSEAVEAIKNA 1148
Score = 34.3 bits (77), Expect = 0.038
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 5/85 (5%)
Query: 18 EIIVETEAQTGVSGINVAGGGK---EGIFVRELREDSPAARSLSLQEGDQLLSAR-VFFE 73
E+I+E G+++ GG I + E+ E+ AAR L GDQ+L V
Sbjct: 1435 EMIIEISKGRSGLGLSIVGGKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLR 1494
Query: 74 NFKYEDALRLLQCAEPYKVSFCLKR 98
N +E+A+ L+ P KV + R
Sbjct: 1495 NSSHEEAITALR-QTPQKVRLVVYR 1518
Score = 33.5 bits (75), Expect = 0.066
Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
Query: 9 EELRRAELVEIIVETEAQTGVSGINVAGG-----GKEGIFVRELREDSPAARSLSLQEGD 63
+++ + +E I TG G +V GK IFV++++ S A R L+E D
Sbjct: 124 QQMAQGRQIEYIDIERPSTGGLGFSVVALRSQNLGKVDIFVKDVQPGSVADRDQRLKEND 183
Query: 64 QLLSAR--VFFENFKYEDALRLLQ 85
Q+L+ +N ++ A+ LLQ
Sbjct: 184 QILAINHTPLDQNISHQQAIALLQ 207
Score = 29.3 bits (64), Expect = 1.2
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 2 EARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQ 60
EA R E L E+ + ++ +A G+ G+++ G G+F+ ++ + A L
Sbjct: 1520 EAHYRDEENL---EIFPVDLQKKAGRGL-GLSIVGKRNGSGVFISDIVKGGAADLDGRLI 1575
Query: 61 EGDQLLSAR-VFFENFKYEDALRLLQCAE 88
+GDQ+LS N E +L+CA+
Sbjct: 1576 QGDQILSVNGEDMRNASQETVATILKCAQ 1604
Score = 28.5 bits (62), Expect = 2.1
Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 6/99 (6%)
Query: 31 GINVAGG-----GKEGIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDALRLL 84
GI++AGG G +F+ ++ AAR+ L+ GD+++S + + D + LL
Sbjct: 1688 GISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHADVVNLL 1747
Query: 85 QCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGPRAK 123
+ A + + T + A +GY + P A+
Sbjct: 1748 KNAYGRIILQVVADTNISAIAAQLENMSTGYHLGSPTAE 1786
Score = 28.1 bits (61), Expect = 2.8
Identities = 28/110 (25%), Positives = 41/110 (37%), Gaps = 13/110 (11%)
Query: 31 GINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLS-ARVFFENFKYEDALRLLQ-CAE 88
G + GG G+ VR + A R LQ GD +L + E ++L+ C
Sbjct: 259 GFGIVGGKTSGVVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLRNCGN 318
Query: 89 PYKVSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLVRVLSPAPALD 138
++ L P GD+++ P P A L V S P D
Sbjct: 319 SVRM---LVARDPAGDISVTP--------PAPAALPVALPTVASKGPGSD 357
Score = 26.9 bits (58), Expect = 6.1
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 3/50 (6%)
Query: 20 IVETEAQTGVSGINVAGG---GKEGIFVRELREDSPAARSLSLQEGDQLL 66
I+E E G+++AG + IFV + + PAA ++ GD+LL
Sbjct: 1239 IIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELL 1288
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 37.7 bits (86), Expect = 0.003
Identities = 25/81 (30%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 12 RRAELVEIIVETEAQTGVS--GINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLL--S 67
R E+ E++ G S G+ G+ GIFV+E++E S A R L+E DQ+L +
Sbjct: 133 RHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILAIN 192
Query: 68 ARVFFENFKYEDALRLLQCAE 88
+ + ++ A+ +LQ A+
Sbjct: 193 GQALDQTITHQQAISILQKAK 213
Score = 32.0 bits (71), Expect = 0.19
Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 8/58 (13%)
Query: 17 VEIIVETEAQTGVSGINVAGGGKE--------GIFVRELREDSPAARSLSLQEGDQLL 66
VE+ E G+S + G G GIF++ + EDSPA ++ +L+ GD+++
Sbjct: 1152 VELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIV 1209
Score = 28.9 bits (63), Expect = 1.6
Identities = 28/114 (24%), Positives = 50/114 (43%), Gaps = 17/114 (14%)
Query: 23 TEAQTGVSGINVAGGGKE---GIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYE 78
++ +TG+ G+++ GG I + E+ E+ A + L GDQ+L + ++
Sbjct: 1633 SKGRTGL-GLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKATHD 1691
Query: 79 DALRLLQCAEPYKVSFCLKR-----------TVPTGDLALRPGTVSGYEIKGPR 121
+A+ +L+ P +V L R T +L +PG G I G R
Sbjct: 1692 EAINVLR-QTPQRVRLTLYRDEAPYKEEEVCDTLTIELQKKPGKGLGLSIVGKR 1744
Score = 28.1 bits (61), Expect = 2.8
Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 43 FVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDALRLLQCAEPYKVSFCLKRTVP 101
F+R + + P S L GD+LL + ++D + +L+ C +RTVP
Sbjct: 577 FIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQDVVNILKELPIEVTMVCCRRTVP 636
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 37.4 bits (85), Expect = 0.005
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 11/93 (11%)
Query: 2 EARSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQE 61
++ SR A + + L +V + G+++ GG G+FV E+ +DSPA L
Sbjct: 1484 QSSSRIAGDANKKTLEPRVVFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVP 1543
Query: 62 GDQLLS-----------ARVFFENFKYEDALRL 83
GD +L V+ E K D +RL
Sbjct: 1544 GDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRL 1576
>gi|42518065 tight junction protein 2 (zona occludens 2) isoform 2
[Homo sapiens]
Length = 1043
Score = 35.0 bits (79), Expect = 0.023
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 31 GINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARV-FFENFKYEDALRLL 84
G+ +AGG GIFV ++E + A + LQEGDQ+L F EDA+ L
Sbjct: 522 GLRLAGGNDVGIFVAGIQEGTSAEQE-GLQEGDQILKVNTQDFRGLVREDAVLYL 575
>gi|42518070 tight junction protein 2 (zona occludens 2) isoform 1
[Homo sapiens]
Length = 1190
Score = 35.0 bits (79), Expect = 0.023
Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 31 GINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARV-FFENFKYEDALRLL 84
G+ +AGG GIFV ++E + A + LQEGDQ+L F EDA+ L
Sbjct: 522 GLRLAGGNDVGIFVAGIQEGTSAEQE-GLQEGDQILKVNTQDFRGLVREDAVLYL 575
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 34.7 bits (78), Expect = 0.029
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 20 IVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKY 77
IV TG+ G N+ GG EGIF+ + PA S L++GDQ+LS V N +
Sbjct: 357 IVIHRGSTGL-GFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 415
Query: 78 EDALRLLQCA 87
E A L+ A
Sbjct: 416 EQAAIALKNA 425
Score = 32.0 bits (71), Expect = 0.19
Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 10/85 (11%)
Query: 11 LRRAELVEIIVETEAQTGVSGI--NVAGG-------GKEGIFVRELREDSPAARSLSLQE 61
+RR E ++E + G G+ ++AGG G I+V ++ E A + LQ
Sbjct: 192 MRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQI 251
Query: 62 GDQLLSAR-VFFENFKYEDALRLLQ 85
GD++L+ V E+ +EDA+ L+
Sbjct: 252 GDKILAVNSVGLEDVMHEDAVAALK 276
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 34.7 bits (78), Expect = 0.029
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 20 IVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKY 77
IV TG+ G N+ GG EGIF+ + PA S L++GDQ+LS V N +
Sbjct: 311 IVIHRGSTGL-GFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 369
Query: 78 EDALRLLQCA 87
E A L+ A
Sbjct: 370 EQAAIALKNA 379
Score = 32.0 bits (71), Expect = 0.19
Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 10/85 (11%)
Query: 11 LRRAELVEIIVETEAQTGVSGI--NVAGG-------GKEGIFVRELREDSPAARSLSLQE 61
+RR E ++E + G G+ ++AGG G I+V ++ E A + LQ
Sbjct: 146 MRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQI 205
Query: 62 GDQLLSAR-VFFENFKYEDALRLLQ 85
GD++L+ V E+ +EDA+ L+
Sbjct: 206 GDKILAVNSVGLEDVMHEDAVAALK 230
>gi|157388993 synaptojanin 2 binding protein [Homo sapiens]
Length = 145
Score = 34.7 bits (78), Expect = 0.029
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 8/65 (12%)
Query: 31 GINVAGGGKE-------GIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDALR 82
G N+ GG + GI+V ++E+ AA LQEGD++LS +N ++DA+
Sbjct: 24 GFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAVD 83
Query: 83 LLQCA 87
L + A
Sbjct: 84 LFRNA 88
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 34.3 bits (77), Expect = 0.038
Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 20 IVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEGDQLLS 67
+V + TG+ G N+ GG EGIFV + PA S LQ GDQ+LS
Sbjct: 319 VVLHKGSTGL-GFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILS 366
Score = 33.9 bits (76), Expect = 0.050
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 10/84 (11%)
Query: 12 RRAELVEIIVETEAQTGVSGI--NVAGG-------GKEGIFVRELREDSPAARSLSLQEG 62
RR ++E +VE + G G+ ++AGG G I+V ++ + A + LQ G
Sbjct: 132 RRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVG 191
Query: 63 DQLLSARVF-FENFKYEDALRLLQ 85
D+LL + E +E+A+ +L+
Sbjct: 192 DRLLMVNNYSLEEVTHEEAVAILK 215
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 34.3 bits (77), Expect = 0.038
Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 20 IVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEGDQLLS 67
+V + TG+ G N+ GG EGIFV + PA S LQ GDQ+LS
Sbjct: 527 VVLHKGSTGL-GFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILS 574
Score = 33.9 bits (76), Expect = 0.050
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 10/84 (11%)
Query: 12 RRAELVEIIVETEAQTGVSGI--NVAGG-------GKEGIFVRELREDSPAARSLSLQEG 62
RR ++E +VE + G G+ ++AGG G I+V ++ + A + LQ G
Sbjct: 288 RRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVG 347
Query: 63 DQLLSARVF-FENFKYEDALRLLQ 85
D+LL + E +E+A+ +L+
Sbjct: 348 DRLLMVNNYSLEEVTHEEAVAILK 371
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 34.3 bits (77), Expect = 0.038
Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 20 IVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEGDQLLS 67
+V + TG+ G N+ GG EGIFV + PA S LQ GDQ+LS
Sbjct: 422 VVLHKGSTGL-GFNIVGGEDGEGIFVSFILAGGPADLSGELQRGDQILS 469
Score = 33.9 bits (76), Expect = 0.050
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 10/84 (11%)
Query: 12 RRAELVEIIVETEAQTGVSGI--NVAGG-------GKEGIFVRELREDSPAARSLSLQEG 62
RR ++E +VE + G G+ ++AGG G I+V ++ + A + LQ G
Sbjct: 183 RRRPILETVVEIKLFKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVG 242
Query: 63 DQLLSARVF-FENFKYEDALRLLQ 85
D+LL + E +E+A+ +L+
Sbjct: 243 DRLLMVNNYSLEEVTHEEAVAILK 266
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 33.9 bits (76), Expect = 0.050
Identities = 32/86 (37%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 4 RSRSAEELRRAELVEIIVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEG 62
R AEE E +II+ + TG+ G N+ GG EGIFV + PA S L+ G
Sbjct: 372 RHMLAEEDFTREPRKIILH-KGSTGL-GFNIVGGEDGEGIFVSFILAGGPADLSGELRRG 429
Query: 63 DQLLSAR-VFFENFKYEDALRLLQCA 87
D++LS V N +E A L+ A
Sbjct: 430 DRILSVNGVNLRNATHEQAAAALKRA 455
>gi|119943108 synapse-associated protein 102 isoform b [Homo
sapiens]
Length = 512
Score = 33.5 bits (75), Expect = 0.066
Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 20 IVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKY 77
I+ + TG+ G N+ GG EGIFV + PA S L+ GD++LS V N +
Sbjct: 50 IILHKGSTGL-GFNIVGGEDGEGIFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATH 108
Query: 78 EDALRLLQCA 87
E A L+ A
Sbjct: 109 EQAAAALKRA 118
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 32.0 bits (71), Expect = 0.19
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 10/84 (11%)
Query: 12 RRAELVEIIVETEAQTGVSGI--NVAGG-------GKEGIFVRELREDSPAARSLSLQEG 62
RR + E I+E + G G+ ++AGG G I+V ++ E A + LQ G
Sbjct: 309 RRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIG 368
Query: 63 DQLLSA-RVFFENFKYEDALRLLQ 85
D+LL+ V E +E+A+ L+
Sbjct: 369 DKLLAVNNVCLEEVTHEEAVTALK 392
Score = 30.0 bits (66), Expect = 0.72
Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 20 IVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEGDQLLS 67
+V TG+ G N+ GG EGIF+ + PA S L++GD+++S
Sbjct: 467 VVLHRGSTGL-GFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIIS 514
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 32.0 bits (71), Expect = 0.19
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 10/84 (11%)
Query: 12 RRAELVEIIVETEAQTGVSGI--NVAGG-------GKEGIFVRELREDSPAARSLSLQEG 62
RR + E I+E + G G+ ++AGG G I+V ++ E A + LQ G
Sbjct: 309 RRKPVSEKIMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIG 368
Query: 63 DQLLSA-RVFFENFKYEDALRLLQ 85
D+LL+ V E +E+A+ L+
Sbjct: 369 DKLLAVNNVCLEEVTHEEAVTALK 392
Score = 30.0 bits (66), Expect = 0.72
Identities = 18/49 (36%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 20 IVETEAQTGVSGINVAGGGK-EGIFVRELREDSPAARSLSLQEGDQLLS 67
+V TG+ G N+ GG EGIF+ + PA S L++GD+++S
Sbjct: 467 VVLHRGSTGL-GFNIVGGEDGEGIFISFILAGGPADLSGELRKGDRIIS 514
>gi|4759306 lin-7 homolog A [Homo sapiens]
Length = 233
Score = 32.0 bits (71), Expect = 0.19
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 31 GINVAGGGKEG--IFVRELREDSPAARSLSLQEGDQLLSAR-VFFENFKYEDALRLLQCA 87
G NV GG ++ I++ + A R L+ GDQLLS V E +E A+ LL+ A
Sbjct: 119 GFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAA 178
Query: 88 E 88
+
Sbjct: 179 K 179
>gi|110346438 FERM and PDZ domain containing 2 isoform 1 [Homo
sapiens]
Length = 1287
Score = 31.2 bits (69), Expect = 0.33
Identities = 17/76 (22%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 15 ELVEIIVETEAQTGVSGI----NVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSA-R 69
E+V + ++ + G + +G GIF+ + PA ++ +++ G Q+L+
Sbjct: 750 EIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNH 809
Query: 70 VFFENFKYEDALRLLQ 85
+ E F + A+R++Q
Sbjct: 810 ISLEGFTFNMAVRMIQ 825
Score = 29.3 bits (64), Expect = 1.2
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 21 VETEAQTGVSGINVAGGGKE-----GIFVRELREDSPAARSLSLQEGDQLL 66
VE + G G +V GG GI+V+ + PAA+ + +GD+LL
Sbjct: 929 VELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLL 979
>gi|110346436 FERM and PDZ domain containing 2 isoform 3 [Homo
sapiens]
Length = 1309
Score = 31.2 bits (69), Expect = 0.33
Identities = 17/76 (22%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 15 ELVEIIVETEAQTGVSGI----NVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSA-R 69
E+V + ++ + G + +G GIF+ + PA ++ +++ G Q+L+
Sbjct: 772 EIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNH 831
Query: 70 VFFENFKYEDALRLLQ 85
+ E F + A+R++Q
Sbjct: 832 ISLEGFTFNMAVRMIQ 847
Score = 29.3 bits (64), Expect = 1.2
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 5/51 (9%)
Query: 21 VETEAQTGVSGINVAGGGKE-----GIFVRELREDSPAARSLSLQEGDQLL 66
VE + G G +V GG GI+V+ + PAA+ + +GD+LL
Sbjct: 951 VELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLL 1001
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 30.8 bits (68), Expect = 0.42
Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 6/82 (7%)
Query: 13 RAELVEIIVETEAQTGVSGINVAGG-----GKEGIFVRELREDSPAARSLSLQEGDQLLS 67
+A ++ IV + Q G ++ GG G GI+V+ + AA LQEGD++L
Sbjct: 210 QASVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIFAGGAAAADGRLQEGDEILE 269
Query: 68 AR-VFFENFKYEDALRLLQCAE 88
++DAL+ + A+
Sbjct: 270 LNGESMAGLTHQDALQKFKQAK 291
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 30.8 bits (68), Expect = 0.42
Identities = 20/61 (32%), Positives = 33/61 (54%), Gaps = 5/61 (8%)
Query: 11 LRRAELVEIIVETEAQTGVSGINVAGG-----GKEGIFVRELREDSPAARSLSLQEGDQL 65
L R ++ II + + G ++AGG G+ GIFV+ + + AA L+EGD++
Sbjct: 578 LIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEI 637
Query: 66 L 66
L
Sbjct: 638 L 638
Score = 27.3 bits (59), Expect = 4.7
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 10/85 (11%)
Query: 9 EELRRAELVEIIVETEAQTGVSGINVAGG-----GKEGIFVRELREDSPAARSLSLQEGD 63
EE+ R +E++ E++ GI V+GG I V +++E A R L GD
Sbjct: 327 EEVGRIWKMELLKESDGL----GIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGD 382
Query: 64 QLLSAR-VFFENFKYEDALRLLQCA 87
+LL +E+A+ +L+ A
Sbjct: 383 ELLVINGHLLVGLSHEEAVAILRSA 407
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,486,741
Number of Sequences: 37866
Number of extensions: 235480
Number of successful extensions: 755
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 685
Number of HSP's gapped (non-prelim): 105
length of query: 147
length of database: 18,247,518
effective HSP length: 93
effective length of query: 54
effective length of database: 14,725,980
effective search space: 795202920
effective search space used: 795202920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.