Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 60498973

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|60498973 myelin transcription factor 1-like [Homo sapiens]
         (1184 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|60498973 myelin transcription factor 1-like [Homo sapiens]        2420   0.0  
gi|17975763 myelin transcription factor 1 [Homo sapiens]              985   0.0  
gi|7662168 suppression of tumorigenicity 18 [Homo sapiens]            759   0.0  
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           84   8e-16
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           84   8e-16
gi|55956788 nucleolin [Homo sapiens]                                   82   2e-15
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    81   5e-15
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    79   3e-14
gi|215422388 death-domain associated protein isoform a [Homo sap...    79   3e-14
gi|215422366 death-domain associated protein isoform b [Homo sap...    79   3e-14
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    77   1e-13
gi|115529449 upstream binding transcription factor, RNA polymera...    75   4e-13
gi|115529451 upstream binding transcription factor, RNA polymera...    75   4e-13
gi|7657671 upstream binding transcription factor, RNA polymerase...    75   4e-13
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    74   8e-13
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    73   1e-12
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    73   1e-12
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    73   1e-12
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               73   2e-12
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            72   2e-12
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...    72   3e-12
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...    72   3e-12
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex...    71   5e-12
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    70   9e-12
gi|21735569 claspin [Homo sapiens]                                     70   2e-11
gi|21735415 centromere protein B [Homo sapiens]                        69   3e-11
gi|21361639 DIPB protein [Homo sapiens]                                69   3e-11
gi|22749303 hypothetical protein LOC196477 [Homo sapiens]              69   3e-11
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    68   5e-11
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     68   6e-11

>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 2420 bits (6273), Expect = 0.0
 Identities = 1184/1184 (100%), Positives = 1184/1184 (100%)

Query: 1    MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60
            MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK
Sbjct: 1    MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60

Query: 61   RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120
            RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE
Sbjct: 61   RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120

Query: 121  DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180
            DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI
Sbjct: 121  DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180

Query: 181  MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 240
            MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN
Sbjct: 181  MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 240

Query: 241  ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 300
            ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV
Sbjct: 241  ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 300

Query: 301  MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 360
            MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH
Sbjct: 301  MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 360

Query: 361  VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 420
            VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS
Sbjct: 361  VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 420

Query: 421  EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 480
            EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP
Sbjct: 421  EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 480

Query: 481  KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 540
            KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA
Sbjct: 481  KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 540

Query: 541  MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 600
            MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD
Sbjct: 541  MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 600

Query: 601  RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 660
            RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA
Sbjct: 601  RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 660

Query: 661  PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 720
            PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY
Sbjct: 661  PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 720

Query: 721  THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 780
            THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP
Sbjct: 721  THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 780

Query: 781  RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 840
            RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE
Sbjct: 781  RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 840

Query: 841  DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 900
            DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE
Sbjct: 841  DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 900

Query: 901  LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 960
            LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ
Sbjct: 901  LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 960

Query: 961  GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 1020
            GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF
Sbjct: 961  GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 1020

Query: 1021 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1080
            LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM
Sbjct: 1021 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1080

Query: 1081 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1140
            EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP
Sbjct: 1081 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1140

Query: 1141 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184
            INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV
Sbjct: 1141 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score =  985 bits (2547), Expect = 0.0
 Identities = 586/1244 (47%), Positives = 758/1244 (60%), Gaps = 183/1244 (14%)

Query: 1    MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60
            M ++ E+KR RTRSK +R P E    +L SCPTPGC GSGHV GKY+RHRS+  CPLAKK
Sbjct: 1    MSLENEDKRARTRSKALRGPPETTAADL-SCPTPGCTGSGHVRGKYSRHRSLQSCPLAKK 59

Query: 61   RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120
            RK +  + +    KRK   +K                       DEG  Y  D+D  G E
Sbjct: 60   RKLEGAEAEHLVSKRKSHPLKLAL--------------------DEG--YGVDSD--GSE 95

Query: 121  DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180
            D E ++    +E E   E  + +  G+D         E    E  E     + +  +  I
Sbjct: 96   DTEVKDASVSDESEGTLEGAEAETSGQD---------EIHRPETAEGRSPVKSHFGSNPI 146

Query: 181  MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRART--ESEMNSNTSNSLEDDSD 238
               T    ++   Y +Y  ++A SLLNLG+IAE+          ++      + L++ ++
Sbjct: 147  GSATA---SSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAE 203

Query: 239  KNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMN 298
               +   + E  L +  +   E V+             S+++  ++  D+ S++ S+   
Sbjct: 204  GAAS--EEGEKGLFIQPEDAEEVVEVT--------TERSQDLCPQSLEDAASEESSKQKG 253

Query: 299  YVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIR 358
             +   +       E+  EE DEE           +  +   +  E   +E   ++     
Sbjct: 254  ILSHEEEDEEEEEEEEEEEEDEE---------EEEEEEEEEEEEEEEEEEEEEEEEEEEE 304

Query: 359  QHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSR--VFASCAKEDGCHERDDDTTSVN 416
            +   P+  F   T   +      L R  E  SP+    V      +D   ++D+DT S  
Sbjct: 305  EEAAPDVIFQEDTSHTSAQKAPEL-RGPESPSPKPEYSVIVEVRSDD---DKDEDTHSRK 360

Query: 417  S---DRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQL 473
            S   D SE    MT+GNL LLE+AIAL+ E+ + + E     A          +QS   L
Sbjct: 361  STVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPA----------EQSQLGL 410

Query: 474  --PGEDRKPKSSDSHVKKPYY--DPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCP 529
              PG+  KP  +   V+K YY  DPSR EK+E KCPTPGCDGTGHVTGLYPHHRSLSGCP
Sbjct: 411  GEPGKAAKPLDT---VRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCP 467

Query: 530  HKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKH-- 587
            HKDR+PPEILAMHE+VLKCPTPGCTG+GHVNSNRN+HRSLSGCPIAAAEKLAK+ EK   
Sbjct: 468  HKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQP 527

Query: 588  QSCDVSKSSQASDRVLRPMCFVKQLEIPQYG-YRNNVPTTTPRSNLAKELEKYSKTSFEY 646
            Q+ D SKSS  SDR+LRPMCFVKQLE+P YG YR NV   TPR+NLAKELEK+SK +F+Y
Sbjct: 528  QTGDPSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDY 587

Query: 647  NSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGG 706
             S+D   +GKR +APK+QT + SPK +                                 
Sbjct: 588  ASFDAQVFGKRMLAPKIQTSETSPKAF--------------------------------- 614

Query: 707  SSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVD 766
                       FDY+ D EAAHMAATAILNLSTRC EMP+NLSTKPQDL  +++ D+EVD
Sbjct: 615  ---------QCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDL-PSKSVDIEVD 664

Query: 767  ENGTLDLSMNKQRPRDSCCP----------ILTP-----LEPMSPQQQAVMNNRCFQLGE 811
            ENGTLDLSM+K R R++  P          + +P         S    ++ + +  Q   
Sbjct: 665  ENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASR 724

Query: 812  GDCWDLPVDYTKMKPRRIDEDESKDITP----------EDLDPFQEALEERRYPGEVTIP 861
             D WD P+DYT  KP R+ E+E ++  P          +D +  +E  EER+YPGEVT+ 
Sbjct: 725  QDEWDRPLDYT--KPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLT 782

Query: 862  SPKPKYPQCKESKKDLIT---------------------LSGCPLADKSIRSMLATSSQE 900
            + K K+   K+ KK+L+T                     LSGCPLADKS+R+++A  S +
Sbjct: 783  NFKLKF-LSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSAD 841

Query: 901  LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 960
            LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSG+++A +K+DKED E ++CPVPGC G 
Sbjct: 842  LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGL 901

Query: 961  GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 1020
            GHI+GKYASHRSASGCPLAA+RQK+G LNGS FSWKS+K EG +CPTPGCDGSGH +GSF
Sbjct: 902  GHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSF 961

Query: 1021 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1080
            LTHRSLSGCPRAT A KK KLSG+++L+ K + S+ +ENDEEIKQL++EI++LNESNS+M
Sbjct: 962  LTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEM 1021

Query: 1081 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1140
            EA M++L++QI++ME NLK IEEENK+IE+QNE+L  EL+ LSQ+LI SLANI+LPHM+P
Sbjct: 1022 EAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEP 1081

Query: 1141 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184
            I EQNFDAYV+TLT+MY+NQD    PENK LLE+IKQAVRGIQV
Sbjct: 1082 ICEQNFDAYVSTLTDMYSNQD----PENKDLLESIKQAVRGIQV 1121


>gi|7662168 suppression of tumorigenicity 18 [Homo sapiens]
          Length = 1047

 Score =  759 bits (1960), Expect = 0.0
 Identities = 424/813 (52%), Positives = 546/813 (67%), Gaps = 80/813 (9%)

Query: 407  ERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYE 466
            E D ++ +V ++   ++ +  KGNL+LLE+AIAL+ ER               +  +  +
Sbjct: 280  EEDSESLAVMTEEGSDL-EKAKGNLSLLEQAIALQAERGCVFH----------NTYKELD 328

Query: 467  DQSPRQLPGEDRKPKSSDSHVKKPYYDPS--RTEKKESKCPTPGCDGTGHVTGLYPHHRS 524
                  L GE R+ K  D   ++ + +    R EK+E+KCP PGCDGTGHVTGLYPHHRS
Sbjct: 329  RFLLEHLAGERRQTKVIDMGGRQIFNNKHSPRPEKRETKCPIPGCDGTGHVTGLYPHHRS 388

Query: 525  LSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQ 584
            LSGCPHK RVP EILAMHE+VLKCPTPGCTGRGHVNSNRN+HRSLSGCPIAAAEKLA +Q
Sbjct: 389  LSGCPHKVRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQ 448

Query: 585  EKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPT---TTPRSNLAKELEKYSK 641
            +K+Q  D  ++ Q  D+  R    VKQ+E        N P+   T+PR+ ++KE EK+ K
Sbjct: 449  DKNQ-LDSPQTGQCPDQAHRTS-LVKQIEF-------NFPSQAITSPRATVSKEQEKFGK 499

Query: 642  TSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNL 701
              F+Y S+D   +GKR +   VQ R   P  + ++K +     P+     +  PS+    
Sbjct: 500  VPFDYASFDAQVFGKRPLIQTVQGRKTPP--FPESKHF-----PNPVKFPNRLPSA---- 548

Query: 702  SCGGGSSASSTCSKSSFDYTHDMEAAHMAATA-ILNLSTRCREMPQNLSTKPQDLCATRN 760
                G+   S    SS+ Y    E  H+AA A ILNLSTRCRE    LS KPQ L A + 
Sbjct: 549  ----GAHTQSPGRASSYSYGQCSEDTHIAAAAAILNLSTRCREATDILSNKPQSLHA-KG 603

Query: 761  PDMEVDENGTLDLSMNKQRPRDSCCPILT-----PLEPMSP-QQQAVMNNRCFQ--LGEG 812
             ++EVDENGTLDLSM K R  D   P+ +     P    SP +  +++ N  F   L + 
Sbjct: 604  AEIEVDENGTLDLSMKKNRILDKSAPLTSSNTSIPTPSSSPFKTSSILVNAAFYQALCDQ 663

Query: 813  DCWDLPVDYTKMKPRRIDEDESKDITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKE 872
            + WD P++Y+K   +  +E E   ++        E LEE+++PGE +IPSPKPK    ++
Sbjct: 664  EGWDTPINYSKTHGKTEEEKEKDPVSS------LENLEEKKFPGEASIPSPKPKL-HARD 716

Query: 873  SKKDLIT---------------------LSGCPLADKSIRSMLATSSQELKCPTPGCDGS 911
             KK+LIT                     +SGCPLADK+++S++A +SQELKCPTPGCDGS
Sbjct: 717  LKKELITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGS 776

Query: 912  GHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHR 971
            GH+TGNYASHRSLSGCPRA+K G+++  +KE+KED E ++CPV GCDGQGHI+GKY SHR
Sbjct: 777  GHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPE-LKCPVIGCDGQGHISGKYTSHR 835

Query: 972  SASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPR 1031
            +ASGCPLAAKRQK+  LNG+  SWK  K E   CP PGC+G GHV+  F+THRSLSGCP 
Sbjct: 836  TASGCPLAAKRQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPL 895

Query: 1032 ATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQI 1091
                +KK K+S E+++TIK +A+ GIE+DEEI+ LDEEIKELNESN ++EADM+KL+TQI
Sbjct: 896  NAQVIKKGKVS-EELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQI 954

Query: 1092 TTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVT 1151
            T+MESNLKTIEEENK+IEQ NESLL ELA LSQ+LI SLA+IQLP M PI+EQNF+AYV 
Sbjct: 955  TSMESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVN 1014

Query: 1152 TLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184
            TLT+MY+N +R  SPE KALLE+IKQAV+GI V
Sbjct: 1015 TLTDMYSNLERDYSPECKALLESIKQAVKGIHV 1047



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 27/35 (77%), Positives = 30/35 (85%)

Query: 26  QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60
           +EL +CPTPGCDGSGHV+G YA HRSV GCPLA K
Sbjct: 719 KELITCPTPGCDGSGHVTGNYASHRSVSGCPLADK 753



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 4/55 (7%)

Query: 26  QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK---RKTQDKQPQEPAPKRKP 77
           QEL  CPTPGCDGSGHV+G YA HRS+ GCP A+K   + T  K+ +E    + P
Sbjct: 764 QEL-KCPTPGCDGSGHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCP 817



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 58/239 (24%), Positives = 88/239 (36%), Gaps = 76/239 (31%)

Query: 1   MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60
           M+ + E+K  RTRSKG  VP++  IQEL                        Y C +AKK
Sbjct: 1   MDAEAEDKTLRTRSKGTEVPMDSLIQEL---------------------SVAYDCSMAKK 39

Query: 61  RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120
           R  +D+    P  KRK   +K    S      +D  ED  ++ ED+G             
Sbjct: 40  RTAEDQALGVPVNKRKSLLMKPRHYS----PKADCQEDRSDRTEDDG------------- 82

Query: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180
             E       EE  I+  DE                                     + +
Sbjct: 83  PLETHGHSTAEEIMIKPMDE-------------------------------------SLL 105

Query: 181 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDK 239
               E      D Y  Y EL+ KSL++LGK  ++ + +  +E+ +N +   SL+ +SD+
Sbjct: 106 STAQENSSRKEDRYSCYQELMVKSLMHLGKFEKNVSVQTVSEN-LNDSGIQSLKAESDE 163



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 26/57 (45%), Positives = 34/57 (59%), Gaps = 2/57 (3%)

Query: 11  RTRSKGVRVPVEPAIQE--LFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQD 65
           R R  GV++      +E     CP  GCDG GH+SGKY  HR+  GCPLA KR+ ++
Sbjct: 794 RARKGGVKMTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGCPLAAKRQKEN 850



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 26/55 (47%), Positives = 33/55 (60%), Gaps = 5/55 (9%)

Query: 17  VRVPVEPAI--QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRK---TQDK 66
           VRVP+E     + +  CPTPGC G GHV+     HRS+ GCP+A   K   +QDK
Sbjct: 396 VRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDK 450



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 18/26 (69%), Positives = 21/26 (80%)

Query: 31  CPTPGCDGSGHVSGKYARHRSVYGCP 56
           CP PGCDG+GHV+G Y  HRS+ GCP
Sbjct: 368 CPIPGCDGTGHVTGLYPHHRSLSGCP 393



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 19/32 (59%), Positives = 23/32 (71%)

Query: 26  QELFSCPTPGCDGSGHVSGKYARHRSVYGCPL 57
           QEL  CP PGC+G GHV+  +  HRS+ GCPL
Sbjct: 864 QELPHCPLPGCNGLGHVNNVFVTHRSLSGCPL 895


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 84.0 bits (206), Expect = 8e-16
 Identities = 55/154 (35%), Positives = 73/154 (47%), Gaps = 22/154 (14%)

Query: 61  RKTQDKQPQEPAPKRKPFAVKADSSSVD-------ECDDSDGTEDMDEKEEDEGEEYSED 113
           R+    QP++   +++    +A S + D       E D          KEE   EEY  D
Sbjct: 123 REPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSD 182

Query: 114 N--------DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEE 165
           +        DE G+  E +EEG  E+ EE EE +ED +ED E  ED EEEEEEEEEEEEE
Sbjct: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242

Query: 166 EENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
           EE E+ +         QD        ++YD   E
Sbjct: 243 EEEEEEEYE-------QDERDQKEEGNDYDTRSE 269



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 34/112 (30%), Positives = 60/112 (53%), Gaps = 8/112 (7%)

Query: 60  KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGD 119
           +R ++  Q  +     + +    ++ S    D+     + +E+  +E  E  E+ +E  +
Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220

Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDH 171
           EDEE +E   EEEEE EEE+E+        E+EEEEE E++E +++EE  D+
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEE--------EEEEEEEYEQDERDQKEEGNDY 264



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 2/114 (1%)

Query: 82  ADSSSVDECDDSDGTEDMDEKEEDEGEEYSED--NDEPGDEDEEDEEGDREEEEEIEEED 139
           +  SS ++ ++++  E+  E++ +E EE  ED   DE  DED E+EE + EEEEE EEE+
Sbjct: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246

Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193
           E++ E  E  + EE  + +   E  +  +E       + R    T+  D    E
Sbjct: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 20/70 (28%), Positives = 37/70 (52%)

Query: 80  VKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED 139
           V+ D    ++ ++ +  ++  E+EE+E EE  E+ +E  +E E+DE   +EE  + +   
Sbjct: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268

Query: 140 EDDDEDGEDV 149
           E  D   E V
Sbjct: 269 EASDSGSESV 278



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 83  DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142
           +   VDE D  +  E+ +E+EE+E EE  E   +  D+ EE  + D   E      +   
Sbjct: 221 EDEEVDE-DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVS 279

Query: 143 DEDGEDVEDEEEEEEEEEEEEEE 165
             DG        +  +E+++E +
Sbjct: 280 FTDGSVRSGSGTDGSDEKKKERK 302


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 84.0 bits (206), Expect = 8e-16
 Identities = 55/154 (35%), Positives = 73/154 (47%), Gaps = 22/154 (14%)

Query: 61  RKTQDKQPQEPAPKRKPFAVKADSSSVD-------ECDDSDGTEDMDEKEEDEGEEYSED 113
           R+    QP++   +++    +A S + D       E D          KEE   EEY  D
Sbjct: 123 REPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSD 182

Query: 114 N--------DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEE 165
           +        DE G+  E +EEG  E+ EE EE +ED +ED E  ED EEEEEEEEEEEEE
Sbjct: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242

Query: 166 EENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
           EE E+ +         QD        ++YD   E
Sbjct: 243 EEEEEEEYE-------QDERDQKEEGNDYDTRSE 269



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 34/112 (30%), Positives = 60/112 (53%), Gaps = 8/112 (7%)

Query: 60  KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGD 119
           +R ++  Q  +     + +    ++ S    D+     + +E+  +E  E  E+ +E  +
Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220

Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDH 171
           EDEE +E   EEEEE EEE+E+        E+EEEEE E++E +++EE  D+
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEE--------EEEEEEEYEQDERDQKEEGNDY 264



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 2/114 (1%)

Query: 82  ADSSSVDECDDSDGTEDMDEKEEDEGEEYSED--NDEPGDEDEEDEEGDREEEEEIEEED 139
           +  SS ++ ++++  E+  E++ +E EE  ED   DE  DED E+EE + EEEEE EEE+
Sbjct: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246

Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193
           E++ E  E  + EE  + +   E  +  +E       + R    T+  D    E
Sbjct: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 20/70 (28%), Positives = 37/70 (52%)

Query: 80  VKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED 139
           V+ D    ++ ++ +  ++  E+EE+E EE  E+ +E  +E E+DE   +EE  + +   
Sbjct: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268

Query: 140 EDDDEDGEDV 149
           E  D   E V
Sbjct: 269 EASDSGSESV 278



 Score = 34.7 bits (78), Expect = 0.55
 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)

Query: 83  DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142
           +   VDE D  +  E+ +E+EE+E EE  E   +  D+ EE  + D   E      +   
Sbjct: 221 EDEEVDE-DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVS 279

Query: 143 DEDGEDVEDEEEEEEEEEEEEEE 165
             DG        +  +E+++E +
Sbjct: 280 FTDGSVRSGSGTDGSDEKKKERK 302


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 61/195 (31%), Positives = 81/195 (41%), Gaps = 56/195 (28%)

Query: 15  KGVRVPVEPAIQELFSCPTPGCDGSGH------VSGKYARHRSVYGCPLAKKRKTQDKQP 68
           K    P +  +    +  TPG  G+          GK        G    K  K +D   
Sbjct: 88  KAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDE 147

Query: 69  QEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-------------EDEGEEYSEDND 115
           +E            D S  DE DD D  ED DE E             EDE +E  ED++
Sbjct: 148 EED-----------DDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDE 196

Query: 116 EPGDEDEEDEEG--------------------------DREEEEEIEEEDEDDDEDGEDV 149
           +  D++E+D E                           D +EEE+ E+ED+DDDED ED 
Sbjct: 197 DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256

Query: 150 EDEEEEEEEEEEEEE 164
           +DE++EEEEEEEEEE
Sbjct: 257 DDEDDEEEEEEEEEE 271



 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 45/136 (33%), Positives = 69/136 (50%), Gaps = 43/136 (31%)

Query: 97  EDMDEKEEDEGEEYSEDNDEPGDEDEEDEE-----------GDREEEEEIEEEDEDDDED 145
           ED DE+E+D+ EE  ED DE  DEDE++ E              +E++E +E+DEDDD+D
Sbjct: 143 EDSDEEEDDDSEEDEED-DEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201

Query: 146 GEDVEDEEE----------------------EEEEEEEEEEEEENEDHQMNCHNTRIMQD 183
            ED  +EE                        E+E+EEE++E+E++D           +D
Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDD---------ED 252

Query: 184 TEKDDNNNDEYDNYDE 199
            E DD+ +DE +  +E
Sbjct: 253 DEDDDDEDDEEEEEEE 268



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 26/114 (22%), Positives = 60/114 (52%), Gaps = 34/114 (29%)

Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGED-----------------VEDEEEEEEEEEEE 162
           ++ + E+ D EE+++ EE++EDD+++ ED                  EDE++E++E++E+
Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197

Query: 163 EEEEENEDHQMNCHNT-----------------RIMQDTEKDDNNNDEYDNYDE 199
           ++++E +D +     T                  + +D ++++++ DE D+ DE
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE 251



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 30/111 (27%), Positives = 58/111 (52%), Gaps = 9/111 (8%)

Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTE--------KDDNNN 191
           ED DE+ ED + EE+EE++E+E+E+E+E E   M         + E        +DD+++
Sbjct: 143 EDSDEE-EDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201

Query: 192 DEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNEN 242
           +E D+ +E +  +     K A+    +A+  +E      +  ++D D +E+
Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDED 252



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 20/69 (28%), Positives = 40/69 (57%), Gaps = 1/69 (1%)

Query: 65  DKQPQEPAP-KRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEE 123
           +++  E  P K K  A      + +  +D D  ED +++++D+ E+  +D+DE  +E+EE
Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266

Query: 124 DEEGDREEE 132
           +EE +  +E
Sbjct: 267 EEEEEPVKE 275


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 43/79 (54%), Positives = 57/79 (72%)

Query: 92  DSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVED 151
           +S   E+ +E+EE+E EE  E+ +E  +E+EEDEE   EEEEE EEE E++ E+ E   +
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943

Query: 152 EEEEEEEEEEEEEEEENED 170
           EEEEEE+EEEEEE EE ED
Sbjct: 944 EEEEEEDEEEEEELEEVED 962



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 36/81 (44%), Positives = 58/81 (71%)

Query: 86  SVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDED 145
           +++  D+ +  E+ +E+EE+E EE  ED +E  +++EE  E + EEEEE EEE E+++ +
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941

Query: 146 GEDVEDEEEEEEEEEEEEEEE 166
            E+ E+EE+EEEEEE EE E+
Sbjct: 942 LEEEEEEEDEEEEEELEEVED 962



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 35/68 (51%), Positives = 50/68 (73%)

Query: 105 DEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEE 164
           DE EE  E+ +E  +E+EE+EE   EEEE+ EE  E+++E+ E+ E+E EEEE E EEEE
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 165 EEENEDHQ 172
           EEE+E+ +
Sbjct: 947 EEEDEEEE 954



 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 42/133 (31%), Positives = 67/133 (50%), Gaps = 12/133 (9%)

Query: 68  PQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG 127
           P  P P   P  +       +      G   ++E         S++ +E  +E+EE+EE 
Sbjct: 843 PPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEE 902

Query: 128 DREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKD 187
           + EEEE+ EEE+ED++E  E+ E+EEEE EEE EEEE E  E+ +            E+D
Sbjct: 903 EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE------------EED 950

Query: 188 DNNNDEYDNYDEL 200
           +   +E +  ++L
Sbjct: 951 EEEEEELEEVEDL 963



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 32/81 (39%), Positives = 57/81 (70%)

Query: 84  SSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD 143
           +SS +E ++ +  E+ +E+EE+E E++ E+ ++  +  EE+EE + E EEE EEE+ + +
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943

Query: 144 EDGEDVEDEEEEEEEEEEEEE 164
           E+ E+ ++EEEEE EE E+ E
Sbjct: 944 EEEEEEDEEEEEELEEVEDLE 964



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 33/76 (43%), Positives = 50/76 (65%)

Query: 88  DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGE 147
           +E ++ +  ED +E+EEDE E + E+ +E  + +EE EE + E EEE EEEDE+++E+ E
Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958

Query: 148 DVEDEEEEEEEEEEEE 163
           +VED E      E EE
Sbjct: 959 EVEDLEFGTAGGEVEE 974



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 1/90 (1%)

Query: 63  TQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDE 122
           + D++ +E   + +    + +     E ++ D  E  +E+EE+E E   E  +E G+ +E
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944

Query: 123 EDEEGDREEEEEIEE-EDEDDDEDGEDVED 151
           E+EE D EEEEE+EE ED +    G +VE+
Sbjct: 945 EEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 17/117 (14%)

Query: 144 EDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203
           E+   V +    +EEEEEEEEEEE E+ +         +D E+++ + +EY   +E    
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEE-----EEEEEDFEEEEEDEEEYFEEEE---- 925

Query: 204 SLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRE 260
                    E+  +    E E         E+D ++ E L    +L        V E
Sbjct: 926 --------EEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 76/295 (25%), Positives = 131/295 (44%), Gaps = 34/295 (11%)

Query: 57  LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116
           ++K    QDK  +    KR+    +   +S    D  + + D  E       +       
Sbjct: 376 ISKYAMLQDKSEEGERKKRR---ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASR 432

Query: 117 PGDEDEEDEEGDREEEEEIEEEDED--DDEDGEDVEDEEEEEEEEEEEEEEEE------- 167
              +DE+DEE D EEEEE EEE+E+  D E+ ED+E  +E +E++EEE+EEEE       
Sbjct: 433 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG 492

Query: 168 --NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM 225
             +    +   N + ++  ++   ++ E  N   +V+ SLL+   +A  +      ES  
Sbjct: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS---IDAESNG 549

Query: 226 NSNTSNSLEDDSDKNENLGRKSE-LSLDLDSDVVRETVDSLK--------LLAQGHGVVL 276
                 +LE++S  ++    + E L LD  S V  +   S K        +L  G G+V 
Sbjct: 550 EQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVS 609

Query: 277 SENMN----DRNYADSMSQ-QDSRNMNYVMLGKPMNNGLMEK---MVEESDEEVC 323
           S + N      N+ DS    + SR         P+ N  +E+   + E++ +++C
Sbjct: 610 STSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKIC 664


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 76/295 (25%), Positives = 131/295 (44%), Gaps = 34/295 (11%)

Query: 57  LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116
           ++K    QDK  +    KR+    +   +S    D  + + D  E       +       
Sbjct: 376 ISKYAMLQDKSEEGERKKRR---ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASR 432

Query: 117 PGDEDEEDEEGDREEEEEIEEEDED--DDEDGEDVEDEEEEEEEEEEEEEEEE------- 167
              +DE+DEE D EEEEE EEE+E+  D E+ ED+E  +E +E++EEE+EEEE       
Sbjct: 433 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG 492

Query: 168 --NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM 225
             +    +   N + ++  ++   ++ E  N   +V+ SLL+   +A  +      ES  
Sbjct: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS---IDAESNG 549

Query: 226 NSNTSNSLEDDSDKNENLGRKSE-LSLDLDSDVVRETVDSLK--------LLAQGHGVVL 276
                 +LE++S  ++    + E L LD  S V  +   S K        +L  G G+V 
Sbjct: 550 EQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVS 609

Query: 277 SENMN----DRNYADSMSQ-QDSRNMNYVMLGKPMNNGLMEK---MVEESDEEVC 323
           S + N      N+ DS    + SR         P+ N  +E+   + E++ +++C
Sbjct: 610 STSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKIC 664


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 76/295 (25%), Positives = 131/295 (44%), Gaps = 34/295 (11%)

Query: 57  LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116
           ++K    QDK  +    KR+    +   +S    D  + + D  E       +       
Sbjct: 388 ISKYAMLQDKSEEGERKKRR---ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASR 444

Query: 117 PGDEDEEDEEGDREEEEEIEEEDED--DDEDGEDVEDEEEEEEEEEEEEEEEE------- 167
              +DE+DEE D EEEEE EEE+E+  D E+ ED+E  +E +E++EEE+EEEE       
Sbjct: 445 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG 504

Query: 168 --NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM 225
             +    +   N + ++  ++   ++ E  N   +V+ SLL+   +A  +      ES  
Sbjct: 505 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS---IDAESNG 561

Query: 226 NSNTSNSLEDDSDKNENLGRKSE-LSLDLDSDVVRETVDSLK--------LLAQGHGVVL 276
                 +LE++S  ++    + E L LD  S V  +   S K        +L  G G+V 
Sbjct: 562 EQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVS 621

Query: 277 SENMN----DRNYADSMSQ-QDSRNMNYVMLGKPMNNGLMEK---MVEESDEEVC 323
           S + N      N+ DS    + SR         P+ N  +E+   + E++ +++C
Sbjct: 622 STSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKIC 676


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 42/107 (39%), Positives = 67/107 (62%), Gaps = 11/107 (10%)

Query: 89  ECDDSDGTED-MDEKEEDE-GEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146
           E  DSD   D +DE+EEDE GE+  +++DE G+E+E DEE D +E+ E +E+D++  E+ 
Sbjct: 154 EAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEE 213

Query: 147 EDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193
           E+   +EE+E+E+E+EEEEE  +  +         +  E DD   D+
Sbjct: 214 EEFGLDEEDEDEDEDEEEEEGGKGEK---------RKRETDDEGEDD 251



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 41/105 (39%), Positives = 61/105 (58%), Gaps = 3/105 (2%)

Query: 65  DKQPQEPAPKRKPFAVKADSSSVDE-CDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEE 123
           D++ QE AP         D    DE  +D +  +D D +EE+  EE  ED D  GDED+ 
Sbjct: 149 DREDQE-APDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD- 206

Query: 124 DEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168
           DE  + EEE  ++EEDED+DED E+ E  + E+ + E ++E E++
Sbjct: 207 DEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%)

Query: 82  ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGD---REEEEEIEEE 138
           A+   VDE ++ +  ED +++++++GEE   D ++  DED E +E D    EEEEE   +
Sbjct: 160 AEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLD 219

Query: 139 DEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170
           +ED+DED ED E+EE  + E+ + E ++E ED
Sbjct: 220 EEDEDED-EDEEEEEGGKGEKRKRETDDEGED 250



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 7/84 (8%)

Query: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEE--EEENE 169
           ED + P  + E D   + EE+EE E+E+++DDEDGE     EEE +EE++E+E  E + +
Sbjct: 151 EDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGE-----EEEFDEEDDEDEDVEGDED 205

Query: 170 DHQMNCHNTRIMQDTEKDDNNNDE 193
           D +++        D E +D + DE
Sbjct: 206 DDEVSEEEEEFGLDEEDEDEDEDE 229



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 29/83 (34%), Positives = 55/83 (66%), Gaps = 4/83 (4%)

Query: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE-EEEEEENEDHQMNCHNTR 179
           D ED+E    + E    ++E++DE+GED EDE++E+ EEEE +EE++E+ED + +  +  
Sbjct: 149 DREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDE 208

Query: 180 IMQDTEK---DDNNNDEYDNYDE 199
           + ++ E+   D+ + DE ++ +E
Sbjct: 209 VSEEEEEFGLDEEDEDEDEDEEE 231



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 18/115 (15%)

Query: 142 DDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELV 201
           +D++  D + E +  +EEEE+EE E+ ED            D + ++   DE D+ DE V
Sbjct: 151 EDQEAPDSDAEVDGVDEEEEDEEGEDEEDE----------DDEDGEEEEFDEEDDEDEDV 200

Query: 202 AKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSD 256
                      ED    +  E E   +  +  ED+ ++ E  G+  +   + D +
Sbjct: 201 EGD--------EDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDE 247



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 1/105 (0%)

Query: 139 DEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNND-EYDNY 197
           D  D ED E  + + E +  +EEEE+EE  ++   +  +    +  E+DD + D E D  
Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205

Query: 198 DELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNEN 242
           D+ V++     G   ED       E E          +  D+ E+
Sbjct: 206 DDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGED 250


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 40/108 (37%), Positives = 64/108 (59%), Gaps = 3/108 (2%)

Query: 50  RSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE 109
           R+ Y   ++ KRK+  K  + P PK     +++ S S  E DD +  +D DE EE+E +E
Sbjct: 605 RAAYKEYISNKRKSMTKL-RGPNPKSSRTTLQSKSES--EEDDEEDEDDEDEDEEEEDDE 661

Query: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157
             + +++ GD  E   E + E+ +E EE+DED+D+D +D EDE+ E E
Sbjct: 662 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 30/94 (31%), Positives = 60/94 (63%), Gaps = 3/94 (3%)

Query: 99  MDEKEEDEGEEYSEDNDEPGDEDEEDEE-GDREEE--EEIEEEDEDDDEDGEDVEDEEEE 155
           +  K E E ++  +++DE  DE+EED+E GD  E+  +  E   ED+ EDG++ E+++E+
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693

Query: 156 EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189
           E+++E+++E+E+NE    +  ++     ++ D N
Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 38/125 (30%)

Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVED--EEEEEEEEEEEEEEEENEDHQMNCHN 177
           E EED+E D ++E+E  +E+E+DDE+G+  ED  +  E   E+E E+ +ENE+       
Sbjct: 639 ESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE------- 689

Query: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237
                D ++DD+ +D+ D                 ED       ESE +S++S+S  D S
Sbjct: 690 ----DDEDEDDDEDDDED-----------------ED------NESEGSSSSSSSSGDSS 722

Query: 238 DKNEN 242
           D + N
Sbjct: 723 DSDSN 727


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 40/108 (37%), Positives = 64/108 (59%), Gaps = 3/108 (2%)

Query: 50  RSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE 109
           R+ Y   ++ KRK+  K  + P PK     +++ S S  E DD +  +D DE EE+E +E
Sbjct: 605 RAAYKEYISNKRKSMTKL-RGPNPKSSRTTLQSKSES--EEDDEEDEDDEDEDEEEEDDE 661

Query: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157
             + +++ GD  E   E + E+ +E EE+DED+D+D +D EDE+ E E
Sbjct: 662 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 30/94 (31%), Positives = 60/94 (63%), Gaps = 3/94 (3%)

Query: 99  MDEKEEDEGEEYSEDNDEPGDEDEEDEE-GDREEE--EEIEEEDEDDDEDGEDVEDEEEE 155
           +  K E E ++  +++DE  DE+EED+E GD  E+  +  E   ED+ EDG++ E+++E+
Sbjct: 634 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693

Query: 156 EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189
           E+++E+++E+E+NE    +  ++     ++ D N
Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 38/125 (30%)

Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVED--EEEEEEEEEEEEEEEENEDHQMNCHN 177
           E EED+E D ++E+E  +E+E+DDE+G+  ED  +  E   E+E E+ +ENE+       
Sbjct: 639 ESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE------- 689

Query: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237
                D ++DD+ +D+ D                 ED       ESE +S++S+S  D S
Sbjct: 690 ----DDEDEDDDEDDDED-----------------ED------NESEGSSSSSSSSGDSS 722

Query: 238 DKNEN 242
           D + N
Sbjct: 723 DSDSN 727


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 40/108 (37%), Positives = 64/108 (59%), Gaps = 3/108 (2%)

Query: 50  RSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE 109
           R+ Y   ++ KRK+  K  + P PK     +++ S S  E DD +  +D DE EE+E +E
Sbjct: 642 RAAYKEYISNKRKSMTKL-RGPNPKSSRTTLQSKSES--EEDDEEDEDDEDEDEEEEDDE 698

Query: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157
             + +++ GD  E   E + E+ +E EE+DED+D+D +D EDE+ E E
Sbjct: 699 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 30/94 (31%), Positives = 60/94 (63%), Gaps = 3/94 (3%)

Query: 99  MDEKEEDEGEEYSEDNDEPGDEDEEDEE-GDREEE--EEIEEEDEDDDEDGEDVEDEEEE 155
           +  K E E ++  +++DE  DE+EED+E GD  E+  +  E   ED+ EDG++ E+++E+
Sbjct: 671 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 730

Query: 156 EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189
           E+++E+++E+E+NE    +  ++     ++ D N
Sbjct: 731 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 38/125 (30%)

Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVED--EEEEEEEEEEEEEEEENEDHQMNCHN 177
           E EED+E D ++E+E  +E+E+DDE+G+  ED  +  E   E+E E+ +ENE+       
Sbjct: 676 ESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE------- 726

Query: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237
                D ++DD+ +D+ D                 ED       ESE +S++S+S  D S
Sbjct: 727 ----DDEDEDDDEDDDED-----------------ED------NESEGSSSSSSSSGDSS 759

Query: 238 DKNEN 242
           D + N
Sbjct: 760 DSDSN 764


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 43/111 (38%), Positives = 65/111 (58%), Gaps = 7/111 (6%)

Query: 97   EDMDEKEEDEGEEYSEDNDEPGDED---EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153
            E   E+EE EGE   E+ +E G+E+   EE+ EG+ EEEEE E E E + E+GE   +EE
Sbjct: 978  EGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEE 1037

Query: 154  EEEEEEEEEEEEEENEDHQMNCHNTR----IMQDTEKDDNNNDEYDNYDEL 200
            E EEE EE E+E E E+++ N           Q+T +++N   + + Y ++
Sbjct: 1038 EGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKV 1088



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 40/86 (46%), Positives = 53/86 (61%), Gaps = 5/86 (5%)

Query: 92   DSDGTEDMDEKEEDEGEEYSEDNDEPGDEDE-----EDEEGDREEEEEIEEEDEDDDEDG 146
            + +G E   E EE+EGE   ED +  G+E+E     E+EEG+ E EEE E E E+ + +G
Sbjct: 922  EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEG 981

Query: 147  EDVEDEEEEEEEEEEEEEEEENEDHQ 172
            E+ E E E EEEE EEE EEE E  +
Sbjct: 982  EEEEGEGEGEEEEGEEEGEEEGEGEE 1007



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 41/83 (49%), Positives = 54/83 (65%), Gaps = 2/83 (2%)

Query: 89  ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDRE-EEEEIEEEDEDDDE-DG 146
           E ++ +G E+  E EE+EGE   E+  E G+ +EE EEG+ E EEEE E E E++ E +G
Sbjct: 836 EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEG 895

Query: 147 EDVEDEEEEEEEEEEEEEEEENE 169
           E+ E E E EEE E E EEEE E
Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGE 918



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 41/116 (35%), Positives = 64/116 (55%), Gaps = 4/116 (3%)

Query: 88   DECDDSDGTEDMD-EKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146
            +E  + +G E+ + E EE EGE   E+ +  G+E+E +EEG+ E E E E E E ++E+ 
Sbjct: 959  EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018

Query: 147  EDVEDE---EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
             +VE E   EE E E EEEE EEE E+ +         ++ E+++    +Y    E
Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE 1074



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 40/114 (35%), Positives = 63/114 (55%), Gaps = 1/114 (0%)

Query: 59  KKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPG 118
           ++++  +++ +E A K +    + D    +E +     E+ +E  E EG E  E   E  
Sbjct: 768 REKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER- 826

Query: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
           +E+EE+ EG+ EE E  EEE E ++E+GE   +EE EE E EEE EE E E  +
Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 36/91 (39%), Positives = 56/91 (61%), Gaps = 1/91 (1%)

Query: 81  KADSSSVDECDDSDGTEDMDEKE-EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED 139
           + +    +E ++ +G E+ +E E E E EE   + +E G+ + E+EEG+ E EEE E E 
Sbjct: 853 EGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEG 912

Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170
           E+++ +G+  E+ EE E E EEEE E E ED
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 37/89 (41%), Positives = 53/89 (59%), Gaps = 4/89 (4%)

Query: 88  DECDDSDGTEDMDEKEEDEGEEYSEDND----EPGDEDEEDEEGDREEEEEIEEEDEDDD 143
           +E ++ +G E+  E EE+EGE   E+ +    E G+E E +EEG+  E E  EEE E + 
Sbjct: 828 EEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887

Query: 144 EDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
           E+  + E EEEE E E EEE E E E+ +
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 41/102 (40%), Positives = 57/102 (55%), Gaps = 20/102 (19%)

Query: 89   ECDDSDGTEDMDEKE-EDEGEEYSEDNDEPGDEDEEDEEGDRE------------EEEEI 135
            E ++ +G  + +E+E E+EGEE  E  +E   E EE+EEG+ E            EEEE 
Sbjct: 980  EGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEG 1039

Query: 136  EEEDEDDDEDGEDVEDEEEEEEEEEEE-------EEEEENED 170
            EEE E+ +++GE  E+    EEEEEEE       EEE E +D
Sbjct: 1040 EEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQD 1081



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 5/95 (5%)

Query: 81   KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEI----- 135
            + +    +E  +  G E+ +E E +  EE  E   E G+ + E+EEG+ E EEE      
Sbjct: 907  EGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG 966

Query: 136  EEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170
            EEE E + E+GE   +EEE E E EEEE EEE E+
Sbjct: 967  EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 41/127 (32%), Positives = 67/127 (52%), Gaps = 18/127 (14%)

Query: 62  KTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDM-----DEKEE---------DEG 107
           + + ++ +E   ++K      +    +E D  +G E+      +EKEE         +EG
Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822

Query: 108 EEYSEDNDEPGDEDEEDEEGDRE----EEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEE 163
           +   E+ +E G+ +EE+ EG+ E    EEEE E + E++ E+GE  E+ EE E E EEEE
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882

Query: 164 EEEENED 170
            E E E+
Sbjct: 883 GEGEGEE 889



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 36/84 (42%), Positives = 50/84 (59%), Gaps = 3/84 (3%)

Query: 89  ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEI---EEEDEDDDED 145
           E ++  G  + +E+E +  EE  E  +E G+ +EE+ EG  EEE E    EEE E+ + +
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877

Query: 146 GEDVEDEEEEEEEEEEEEEEEENE 169
           GE+ E E E EEE E E EEEE E
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGE 901



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 40/110 (36%), Positives = 61/110 (55%), Gaps = 7/110 (6%)

Query: 67   QPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE- 125
            + +E   K +    + +    +E  + +G +   E EE+EGE   E+ +  G+ +EE E 
Sbjct: 913  EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972

Query: 126  -----EGDREEEE-EIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169
                 EG+ EEEE E E E+E+ +E+GE+  + EEE E E EEEEE E E
Sbjct: 973  EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 6/96 (6%)

Query: 81  KADSSSVDECDDSDGTEDMD-EKEEDEGEEYSEDNDEPGDEDEE-----DEEGDREEEEE 134
           + +    +E  + +G E+ + E EE+EGE   E+  E   E+EE     +EEG+  E E 
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932

Query: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170
            EEE E + EDGE   +EEE E E EEEE E E E+
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 9/163 (5%)

Query: 81   KADSSSVDECDDSDGTEDMD-EKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEE-EIEEE 138
            + +    +E  + +G E+ + E EE+EGE   E+  E G+ + E+EEG+ E E+ E E E
Sbjct: 890  EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGE 949

Query: 139  DEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYD 198
            +E+ + +GE+ E E E EEE E E EE E E  +         ++ E++     E +   
Sbjct: 950  EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009

Query: 199  ELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241
            E         G+  E+       E E         E + +  E
Sbjct: 1010 E-------GEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045



 Score = 61.6 bits (148), Expect = 4e-09
 Identities = 38/83 (45%), Positives = 50/83 (60%), Gaps = 2/83 (2%)

Query: 88  DECDDSDGTEDMDEKE-EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146
           +E  + +G E+  E E E+EGE   E+ +  G  +EE EEG+ E EEE E E E +D +G
Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE-EGEGEGEDGEG 946

Query: 147 EDVEDEEEEEEEEEEEEEEEENE 169
           E  E+E E E EEEE E E E E
Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEE 969



 Score = 60.5 bits (145), Expect = 9e-09
 Identities = 35/114 (30%), Positives = 63/114 (55%), Gaps = 1/114 (0%)

Query: 60  KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-EDEGEEYSEDNDEPG 118
           K + ++++ +    + +    + +    +E  +  G E+ +E E E+EGEE   + +E  
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882

Query: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
            E E +EEG+ E EEE  E + +++ +GE  E+E E + EEE EE E E E+ +
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 38/92 (41%), Positives = 56/92 (60%), Gaps = 8/92 (8%)

Query: 89  ECDDSDGTEDMDEKEEDEGEEYSEDND--EPGDEDEEDEEGDREEEEEIEE-----EDED 141
           E ++ +G  + +E+ E EGEE   + +  E G+ + E+EEG+ + EEE EE     E+E+
Sbjct: 877 EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936

Query: 142 DDEDGEDVEDEEEEEE-EEEEEEEEEENEDHQ 172
            + +GED E E EEEE E E EEEE E E  +
Sbjct: 937 GEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 36/143 (25%), Positives = 72/143 (50%), Gaps = 2/143 (1%)

Query: 59  KKR--KTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116
           KKR  + Q+++ +E   +++      +    +  +  +   D +E+EE EGE   E   E
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE 762

Query: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCH 176
             + + E EEG+R++EE   +E++ ++E  +   +EEE E   EE+EE  E E  ++   
Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822

Query: 177 NTRIMQDTEKDDNNNDEYDNYDE 199
                ++ E+ +   +E +  +E
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEE 845



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 51/178 (28%), Positives = 81/178 (45%), Gaps = 38/178 (21%)

Query: 94  DGTEDMDEKEE---DEGEEYSEDNDEPGDEDE----------------EDEEGDREEEEE 134
           +G +++ EKEE    +GEE  +   E G + E                E+EEGDREEEEE
Sbjct: 691 EGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEE 750

Query: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEE----EEENEDHQMNCHNTRIMQDTEKDDNN 190
            E E +++ E GE+VE E E+EE E ++EE    EE+ E+        +   + E+ +  
Sbjct: 751 KEGEGKEEGE-GEEVEGEREKEEGERKKEERAGKEEKGEE-----EGDQGEGEEEETEGR 804

Query: 191 NDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248
            +E +   E+        G++ E    R   E E         E + ++ E  G + E
Sbjct: 805 GEEKEEGGEVEG------GEVEEGKGER---EEEEEEGEGEEEEGEGEEEEGEGEEEE 853



 Score = 57.8 bits (138), Expect = 6e-08
 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 15/92 (16%)

Query: 91  DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREE--EEEIEEEDEDDDEDGE- 147
           ++ +G E   E+E++EGE   E+    G E++ +EEGD+ E  EEE E   E+ +E GE 
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEER--AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814

Query: 148 ----------DVEDEEEEEEEEEEEEEEEENE 169
                     + E+EEEE E EEEE E EE E
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 8/127 (6%)

Query: 91   DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE-----DEDDDED 145
            ++ +G  + +E+ E EGE   E+ +  G+E+E +EEG+  E+E   EE     +E+++E+
Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066

Query: 146  G---EDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVA 202
            G   E  E+E E ++ EE ++  +     +   H T   +       N  E  +   + +
Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQS 1126

Query: 203  KSLLNLG 209
            K LL  G
Sbjct: 1127 KRLLKNG 1133



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 14/112 (12%)

Query: 91  DDSDGTEDMDEKEEDEGEEYSE--DNDEPGD------EDEEDEEGDREEEEEIEEEDEDD 142
           + S G E   ++E ++GE+     + + PG+      E EE ++ D EE+E+ E E    
Sbjct: 661 EGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQ 720

Query: 143 DEDGEDVED--EEE----EEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDD 188
            E  +++E+  EEE    EEEE + EEEEE+  + +       +  + EK++
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEE 772



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 43/189 (22%), Positives = 86/189 (45%), Gaps = 20/189 (10%)

Query: 84  SSSVDECDDS-DGTEDMDEKEEDEGEEYSEDND-EPGDEDEEDEEGDR--EEEEEIEEED 139
           + SV E +D  +G  D   +E   G E+ +D + E G++D+   E +R  E E+E+ E++
Sbjct: 641 AKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKE 700

Query: 140 EDDDEDGEDVEDEEEEEEEEEEE----EEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYD 195
           E    DGE      E+E++E E+    E  +E E+     H     ++ ++++    E +
Sbjct: 701 EWKKRDGE------EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754

Query: 196 NYDELVAKSLLNLGKIAEDAAYRARTE----SEMNSNTSNSLEDDSDKNENLGRKSELSL 251
             +E   + +   G+  ++   R + E     E      +  E + ++ E  G + E   
Sbjct: 755 GKEEGEGEEV--EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812

Query: 252 DLDSDVVRE 260
           +++   V E
Sbjct: 813 EVEGGEVEE 821



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 13/169 (7%)

Query: 93  SDGTEDMDEKEEDEGEEYSEDNDEP-GDEDEEDEEGD------REEEEEIEEEDEDDDED 145
           SD   D  E  E + +   E  D P G  D   EEG       ++EE E  E+D+   E 
Sbjct: 627 SDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEM 686

Query: 146 GEDVEDEEEEEEEEE------EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
               E E+E  E+EE      EE+E++E E       N  + +  E++    +E +   E
Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDRE 746

Query: 200 LVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248
              +      +  E        E E             +K E  G + E
Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGE 795



 Score = 38.5 bits (88), Expect = 0.038
 Identities = 50/245 (20%), Positives = 88/245 (35%), Gaps = 41/245 (16%)

Query: 57  LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEG--------- 107
           L    K+    P +   K++        +++ E DDSD  E+M E +E +          
Sbjct: 508 LNSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGI 567

Query: 108 ---------EEYSEDNDEPGDEDE--EDEEGDREEEEEIEEEDEDDDEDG---------- 146
                    E +S++  E  +E E  ED +G+  EE+E+E  +E+    G          
Sbjct: 568 FMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILS 627

Query: 147 EDVEDEEEEEE-------EEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
           +D+ D+ E  E       E E+  E   +   +         QD E++    D+     E
Sbjct: 628 DDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEME 687

Query: 200 LVAKSLLNLGKIAE----DAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDS 255
              +    L +  E    D   + + E E       + E +    E  G   E   D + 
Sbjct: 688 RPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREE 747

Query: 256 DVVRE 260
           +  +E
Sbjct: 748 EEEKE 752


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 44/125 (35%), Positives = 64/125 (51%), Gaps = 27/125 (21%)

Query: 94  DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG------DREEEEEIEEEDEDDDED-- 145
           DG +  D +  D  EE  ED DE  +E+EE+E G      + EEEEE E+EDED+DED  
Sbjct: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205

Query: 146 -----------------GEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDD 188
                             E+++DEE++++  EE EEEEE E+  +     +  +D E D 
Sbjct: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK--RDAEDDG 263

Query: 189 NNNDE 193
              D+
Sbjct: 264 EEEDD 268



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%)

Query: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169
           EDN+ P  E+E+DE+GD ++EEE E E    +  E+ E+ E+EE+E+E+E+E+E   E  
Sbjct: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 210

Query: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194
           + +     + +M++  +D+ ++D+Y
Sbjct: 211 EGEEEVGLSYLMKEEIQDEEDDDDY 235



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 29/93 (31%)

Query: 88  DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE-------------------DEED---- 124
           +E    +G E+ +E+EE+E E+  ED DE G E                   DEED    
Sbjct: 176 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 235

Query: 125 -EEGDREEEEEI-----EEEDEDDDEDGEDVED 151
            EEG+ EEEEE      E+   D ++DGE+ +D
Sbjct: 236 VEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 25/99 (25%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 145 DGEDVEDEE--EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVA 202
           DG D ED E  + EEE++E+ +E++ E+ +         ++ E+++   DE ++ DE  A
Sbjct: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205

Query: 203 KSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241
            S L  G+     +Y  + E +   +  + +E+  ++ E
Sbjct: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 244



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%)

Query: 64  QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105
           +D + +E      P   + +    +E +D D  ED DE                  KEE 
Sbjct: 168 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 226

Query: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145
           + EE  +D  E G+E+EE+ E G R E+ + + ED+ ++ED
Sbjct: 227 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 44/125 (35%), Positives = 64/125 (51%), Gaps = 27/125 (21%)

Query: 94  DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG------DREEEEEIEEEDEDDDED-- 145
           DG +  D +  D  EE  ED DE  +E+EE+E G      + EEEEE E+EDED+DED  
Sbjct: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164

Query: 146 -----------------GEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDD 188
                             E+++DEE++++  EE EEEEE E+  +     +  +D E D 
Sbjct: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK--RDAEDDG 222

Query: 189 NNNDE 193
              D+
Sbjct: 223 EEEDD 227



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%)

Query: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169
           EDN+ P  E+E+DE+GD ++EEE E E    +  E+ E+ E+EE+E+E+E+E+E   E  
Sbjct: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 169

Query: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194
           + +     + +M++  +D+ ++D+Y
Sbjct: 170 EGEEEVGLSYLMKEEIQDEEDDDDY 194



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 29/93 (31%)

Query: 88  DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE-------------------DEED---- 124
           +E    +G E+ +E+EE+E E+  ED DE G E                   DEED    
Sbjct: 135 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 194

Query: 125 -EEGDREEEEEI-----EEEDEDDDEDGEDVED 151
            EEG+ EEEEE      E+   D ++DGE+ +D
Sbjct: 195 VEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 25/99 (25%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 145 DGEDVEDEE--EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVA 202
           DG D ED E  + EEE++E+ +E++ E+ +         ++ E+++   DE ++ DE  A
Sbjct: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164

Query: 203 KSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241
            S L  G+     +Y  + E +   +  + +E+  ++ E
Sbjct: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 203



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%)

Query: 64  QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105
           +D + +E      P   + +    +E +D D  ED DE                  KEE 
Sbjct: 127 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 185

Query: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145
           + EE  +D  E G+E+EE+ E G R E+ + + ED+ ++ED
Sbjct: 186 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 44/125 (35%), Positives = 64/125 (51%), Gaps = 27/125 (21%)

Query: 94  DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG------DREEEEEIEEEDEDDDED-- 145
           DG +  D +  D  EE  ED DE  +E+EE+E G      + EEEEE E+EDED+DED  
Sbjct: 98  DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 157

Query: 146 -----------------GEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDD 188
                             E+++DEE++++  EE EEEEE E+  +     +  +D E D 
Sbjct: 158 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK--RDAEDDG 215

Query: 189 NNNDE 193
              D+
Sbjct: 216 EEEDD 220



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%)

Query: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169
           EDN+ P  E+E+DE+GD ++EEE E E    +  E+ E+ E+EE+E+E+E+E+E   E  
Sbjct: 103 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 162

Query: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194
           + +     + +M++  +D+ ++D+Y
Sbjct: 163 EGEEEVGLSYLMKEEIQDEEDDDDY 187



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 29/93 (31%)

Query: 88  DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE-------------------DEED---- 124
           +E    +G E+ +E+EE+E E+  ED DE G E                   DEED    
Sbjct: 128 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 187

Query: 125 -EEGDREEEEEI-----EEEDEDDDEDGEDVED 151
            EEG+ EEEEE      E+   D ++DGE+ +D
Sbjct: 188 VEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 25/99 (25%), Positives = 51/99 (51%), Gaps = 2/99 (2%)

Query: 145 DGEDVEDEE--EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVA 202
           DG D ED E  + EEE++E+ +E++ E+ +         ++ E+++   DE ++ DE  A
Sbjct: 98  DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 157

Query: 203 KSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241
            S L  G+     +Y  + E +   +  + +E+  ++ E
Sbjct: 158 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 196



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%)

Query: 64  QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105
           +D + +E      P   + +    +E +D D  ED DE                  KEE 
Sbjct: 120 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 178

Query: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145
           + EE  +D  E G+E+EE+ E G R E+ + + ED+ ++ED
Sbjct: 179 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 219


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 27/165 (16%)

Query: 91  DDSDGTEDMDEKEEDEGEEYSEDNDEPGDED-EEDEEGDREEEEEIEEED----EDDDED 145
           ++ D  ED +++ E++GE   ED DE G+ED +ED+ G+ + E+  E+ED    ED   +
Sbjct: 126 EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGN 185

Query: 146 GEDVEDEEEEEEEEEEEEEE---EENED-----HQMNCHNTRIMQD-TEKDDNNNDEYDN 196
           GED +++ E+E+EEE+ +E    +ENED      +    + ++ +D  E++D   DE  N
Sbjct: 186 GEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGN 245

Query: 197 YDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241
            +E         GK  ED       E E         EDD  K E
Sbjct: 246 EEE--------AGKEKEDL-----KEEEEGKEEDEIKEDDGKKEE 277



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 21/101 (20%)

Query: 91  DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEED---EEGDREE-------EEEIEEEDE 140
           D     ED  EK EDE EE  ED  E GD  E +   E+GD++E       E+E E ED 
Sbjct: 181 DGKGNGEDGKEKGEDEKEE--EDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDG 238

Query: 141 DDDEDG---------EDVEDEEEEEEEEEEEEEEEENEDHQ 172
            +DE G         ED+++EEE +EE+E +E++ + E+ Q
Sbjct: 239 KEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQ 279



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 36/177 (20%), Positives = 80/177 (45%), Gaps = 1/177 (0%)

Query: 72  APKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREE 131
           AP  +   V+    ++++  +  G +      E + EE  +  DE    +E+ E G  ++
Sbjct: 90  APASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDK 149

Query: 132 EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNN 191
           +E+ EE+ ++D    E  ED +E+E+ ++ E+ +   ED +    + +  +D ++  +  
Sbjct: 150 DEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK 209

Query: 192 DEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248
           +  D  ++   K   ++ K+ ED   R   + +   N   + ++  D  E    K E
Sbjct: 210 ENEDGKEKGDKKEGKDV-KVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 4/80 (5%)

Query: 88  DECDDSDGTEDMDEKE---EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDE 144
           D  +  DG E+ D KE   + EG++     DE   ED +++EG  EEE   E+ED  ++E
Sbjct: 201 DRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260

Query: 145 DGEDVEDEEEEEEEEEEEEE 164
           +G++ EDE +E++ ++EE +
Sbjct: 261 EGKE-EDEIKEDDGKKEEPQ 279



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 45/185 (24%), Positives = 80/185 (43%), Gaps = 25/185 (13%)

Query: 63  TQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDE 122
           T + +P+  +  RK   +K  S  ++E  D+      + K+E   EE   +N + G+   
Sbjct: 31  TPEVKPKRTSSSRK---MKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKI 87

Query: 123 EDEEGDREE-----EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHN 177
            +     +E     EE IE+  E   E  E V  E + EEE+++E+EE++NE        
Sbjct: 88  TEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNE-------- 139

Query: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237
                  EK +   ++ D   E   K   N  +  EDA  + + + +   +   + ED  
Sbjct: 140 -------EKGEAGKEDKDEKGEEDGKEDKNGNEKGEDA--KEKEDGKKGEDGKGNGEDGK 190

Query: 238 DKNEN 242
           +K E+
Sbjct: 191 EKGED 195



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 42/196 (21%), Positives = 82/196 (41%), Gaps = 20/196 (10%)

Query: 58  AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEK--EEDEGEEYSEDND 115
           ++K KT+    +E          +    +V E D ++  ++ + K  E    E+   +  
Sbjct: 42  SRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVK 101

Query: 116 EPGDEDEEDEEGDREEE--EEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQM 173
           E   ED  ++ G+++E    E++ E+ED  ED ED    + EE+ E  +E+++E  +   
Sbjct: 102 EENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEED----QNEEKGEAGKEDKDEKGE--- 154

Query: 174 NCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGK-IAEDAAYRARTESEMNSNTSNS 232
                   +D ++D N N++ ++  E         GK   ED   +   E E        
Sbjct: 155 --------EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETG 206

Query: 233 LEDDSDKNENLGRKSE 248
              +++  +  G K E
Sbjct: 207 DGKENEDGKEKGDKKE 222



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%)

Query: 60  KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTE---DMDEKEEDEGEEYSEDNDE 116
           K K +D++ +E   +++    K +    ++ D  +G +     DEKE ++G+E    N+E
Sbjct: 190 KEKGEDEKEEED--RKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEE 247

Query: 117 P-GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152
             G E E     D +EEEE +EEDE  ++DG+  E +
Sbjct: 248 EAGKEKE-----DLKEEEEGKEEDEIKEDDGKKEEPQ 279


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 39/131 (29%), Positives = 68/131 (51%), Gaps = 6/131 (4%)

Query: 67  QPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEE 126
           +P+E  P+      +AD ++V++ + +D   +  E E +E E+  E+N  P + +E+ + 
Sbjct: 525 EPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREEN-LPDENEEQKQS 583

Query: 127 GDREEEEEIEEE-----DEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIM 181
             ++E  E+EE      + D  ED  D + +EE EEE +E+  EE+  + + N   T   
Sbjct: 584 NQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGE 643

Query: 182 QDTEKDDNNND 192
            D   DD NND
Sbjct: 644 NDENTDDKNND 654



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 43/213 (20%), Positives = 91/213 (42%), Gaps = 26/213 (12%)

Query: 57  LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116
           L ++ + ++ +PQ     R+     A  + + +  +  G +  +   E + +   E   +
Sbjct: 460 LQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGD 519

Query: 117 PGDEDEEDEEGDREEEEEIE----------------EEDEDDDEDGEDVEDEEEEEEEEE 160
           PG+  E  E+G RE + E E                 + ED+ E+ E V +E   +E EE
Sbjct: 520 PGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEE 579

Query: 161 EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRAR 220
           +++  ++ E+ ++  H        +++DN +++Y    E          ++ ED     +
Sbjct: 580 QKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAE---------EEVQEDLTEEKK 630

Query: 221 TESEMNS-NTSNSLEDDSDKNENLGRKSELSLD 252
            E E N+  T    ++++D   N G + E+  D
Sbjct: 631 RELEHNAEETYGENDENTDDKNNDGEEQEVRDD 663



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 9/80 (11%)

Query: 100 DEKEEDEGEEYSEDNDEPGDED---EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156
           D++E++  E+Y E+ +E   ED   E+  E +   EE   E DE+ D+   D E++E  +
Sbjct: 603 DQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRD 662

Query: 157 E------EEEEEEEEEENED 170
           +      EE  EEEEEE ED
Sbjct: 663 DNRPKGREEHYEEEEEEEED 682



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 38/163 (23%), Positives = 70/163 (42%), Gaps = 7/163 (4%)

Query: 9   RHRTRSKGVRV--PVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVY--GCPLAKKRKTQ 64
           RH  R +G R   P   A +       P  D +     ++     V     P   + + Q
Sbjct: 523 RHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQ 582

Query: 65  DKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEED 124
             Q QE     +   +   + + D+ +D+   +  +E EE+  E+ +E+     + + E+
Sbjct: 583 SNQKQENTEVEEHLVM---AGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639

Query: 125 EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167
             G+ +E  + +  D ++ E  +D   +  EE  EEEEEEEE+
Sbjct: 640 TYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEED 682



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 33/186 (17%), Positives = 74/186 (39%), Gaps = 14/186 (7%)

Query: 79  AVKADSSSVDECDDSDGTEDMDEKE-------EDEGEEYSEDNDEPGDEDEEDEEGDREE 131
           A + D+   DE +   G      ++       E E +  + ++  P D+     E + EE
Sbjct: 505 AYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEE 564

Query: 132 EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE-------EEEEENEDHQMNCHNTRIMQDT 184
            E++ EE+  D+ + +   ++++E  E EE        +++E+N D Q        +Q+ 
Sbjct: 565 AEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQED 624

Query: 185 EKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLG 244
             ++   +   N +E   ++  N      D   +   +           E++ ++ E+  
Sbjct: 625 LTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGA 684

Query: 245 RKSELS 250
             +E S
Sbjct: 685 AVAEKS 690



 Score = 35.4 bits (80), Expect = 0.32
 Identities = 26/113 (23%), Positives = 47/113 (41%), Gaps = 7/113 (6%)

Query: 101 EKEEDEGEEYSEDNDE-------PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153
           EK   E +E S +ND        PG  ++        +E E +   E   ++ E  E EE
Sbjct: 273 EKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEE 332

Query: 154 EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLL 206
            + EEE  +  EEE  +      +     D   ++ + +  + +++  A +LL
Sbjct: 333 HQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLL 385



 Score = 35.0 bits (79), Expect = 0.42
 Identities = 49/227 (21%), Positives = 86/227 (37%), Gaps = 39/227 (17%)

Query: 123 EDEEGDREEEEEIEEEDEDDDEDGEDVEDEE------EEEEEEEEEEEEEENEDHQMNCH 176
           E EEG  + +E++ ++   D  D + V+  E      EE   E + + ++E E    N H
Sbjct: 465 ELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRH 524

Query: 177 NTRIMQDTE-----------------KDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRA 219
             R     E                  DD NN   D ++E  A+ +       E+   + 
Sbjct: 525 EPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEE--AEQVREENLPDENEEQKQ 582

Query: 220 RTESEMNSNTSNSL-----EDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGV 274
             + + N+     L      D  + N +   + E   ++  D+  E    L+  A+    
Sbjct: 583 SNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYG 642

Query: 275 VLSENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEE 321
              EN +D+N  +   +Q+ R+ N     +P   G  E   EE +EE
Sbjct: 643 ENDENTDDKN--NDGEEQEVRDDN-----RP--KGREEHYEEEEEEE 680


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 42/107 (39%), Positives = 60/107 (56%), Gaps = 17/107 (15%)

Query: 89  ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGED 148
           E  DSD   D  +KEE+         DE G+++++ E  D EEEE  EEEDED+D +G+D
Sbjct: 174 EAPDSDAQVDGVDKEEE---------DEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDD 224

Query: 149 VEDEEEEEEEE--------EEEEEEEENEDHQMNCHNTRIMQDTEKD 187
            +DE  EEEEE        +E+E+E+E E+      N +   D E+D
Sbjct: 225 DKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 39/94 (41%), Positives = 58/94 (61%), Gaps = 6/94 (6%)

Query: 82  ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE- 140
           A    VD+ ++ +  ED  + E ++GEE  E+ DE  DEDE D EGD +++E  EEE+E 
Sbjct: 180 AQVDGVDKEEEDEEGEDEKDXENEDGEE--EELDEEEDEDE-DVEGDDDKDEVSEEEEEF 236

Query: 141 --DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
             D DED ED +++EEEEE  + E  + E +D +
Sbjct: 237 GLDKDEDDEDEDEDEEEEESGKGENRKRETDDEE 270



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 37/107 (34%), Positives = 60/107 (56%), Gaps = 3/107 (2%)

Query: 63  TQDKQPQEPAPKRKPFAVKADSSSVDE-CDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED 121
           T D + QE AP         D    DE  +D    E+ D +EE+  EE  ED D  GD+D
Sbjct: 167 TYDPEDQE-APDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDD 225

Query: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168
           + DE  + EEE  ++++++D+DED ++ E+E  + E  + E ++EE+
Sbjct: 226 K-DEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 32/92 (34%), Positives = 56/92 (60%), Gaps = 2/92 (2%)

Query: 108 EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167
           + Y  ++ E  D D + +  D+EEE+E E EDE D E+ ED E+EE +EEE+E+E+ E +
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDE-EGEDEKDXEN-EDGEEEELDEEEDEDEDVEGD 223

Query: 168 NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
           ++  +++        D ++DD + DE +  +E
Sbjct: 224 DDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEE 255



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 24/59 (40%), Positives = 38/59 (64%), Gaps = 1/59 (1%)

Query: 88  DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146
           DE +D +G +D DE  E+E EE+  D DE  ++++EDEE +   + E  + + DD+EDG
Sbjct: 215 DEDEDVEGDDDKDEVSEEE-EEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 21/109 (19%), Positives = 51/109 (46%), Gaps = 10/109 (9%)

Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
           + +D++  D + + +  ++EEE+EE E+ +D +        + + E +D + +  D+ DE
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDE 228

Query: 200 LVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248
           +            E+  +    + +      +  E++S K EN  R+++
Sbjct: 229 V----------SEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETD 267


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 42/107 (39%), Positives = 60/107 (56%), Gaps = 17/107 (15%)

Query: 89  ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGED 148
           E  DSD   D  +KEE+         DE G+++++ E  D EEEE  EEEDED+D +G+D
Sbjct: 174 EAPDSDAQVDGVDKEEE---------DEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDD 224

Query: 149 VEDEEEEEEEE--------EEEEEEEENEDHQMNCHNTRIMQDTEKD 187
            +DE  EEEEE        +E+E+E+E E+      N +   D E+D
Sbjct: 225 DKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 39/94 (41%), Positives = 58/94 (61%), Gaps = 6/94 (6%)

Query: 82  ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE- 140
           A    VD+ ++ +  ED  + E ++GEE  E+ DE  DEDE D EGD +++E  EEE+E 
Sbjct: 180 AQVDGVDKEEEDEEGEDEKDXENEDGEE--EELDEEEDEDE-DVEGDDDKDEVSEEEEEF 236

Query: 141 --DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
             D DED ED +++EEEEE  + E  + E +D +
Sbjct: 237 GLDKDEDDEDEDEDEEEEESGKGENRKRETDDEE 270



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 37/107 (34%), Positives = 60/107 (56%), Gaps = 3/107 (2%)

Query: 63  TQDKQPQEPAPKRKPFAVKADSSSVDE-CDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED 121
           T D + QE AP         D    DE  +D    E+ D +EE+  EE  ED D  GD+D
Sbjct: 167 TYDPEDQE-APDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDD 225

Query: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168
           + DE  + EEE  ++++++D+DED ++ E+E  + E  + E ++EE+
Sbjct: 226 K-DEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 32/92 (34%), Positives = 56/92 (60%), Gaps = 2/92 (2%)

Query: 108 EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167
           + Y  ++ E  D D + +  D+EEE+E E EDE D E+ ED E+EE +EEE+E+E+ E +
Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDE-EGEDEKDXEN-EDGEEEELDEEEDEDEDVEGD 223

Query: 168 NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
           ++  +++        D ++DD + DE +  +E
Sbjct: 224 DDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEE 255



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 24/59 (40%), Positives = 38/59 (64%), Gaps = 1/59 (1%)

Query: 88  DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146
           DE +D +G +D DE  E+E EE+  D DE  ++++EDEE +   + E  + + DD+EDG
Sbjct: 215 DEDEDVEGDDDKDEVSEEE-EEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 21/109 (19%), Positives = 51/109 (46%), Gaps = 10/109 (9%)

Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
           + +D++  D + + +  ++EEE+EE E+ +D +        + + E +D + +  D+ DE
Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDE 228

Query: 200 LVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248
           +            E+  +    + +      +  E++S K EN  R+++
Sbjct: 229 V----------SEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETD 267


>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
           exchanger), member 1 [Homo sapiens]
          Length = 1099

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 43/137 (31%), Positives = 72/137 (52%), Gaps = 22/137 (16%)

Query: 58  AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-EDEGEEYSEDNDE 116
           A + +T++K   E  P+ +           +EC+D +  E   + E EDEGE ++ED + 
Sbjct: 764 AGEGETEEKSGGETQPEGE--GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEM 821

Query: 117 PGDEDEED-------------------EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157
            G+E E +                   E+G   +  + EEE+E+++E  E+ E+EE+EEE
Sbjct: 822 KGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEE 881

Query: 158 EEEEEEEEEENEDHQMN 174
           EEEEEEEEE+  +  ++
Sbjct: 882 EEEEEEEEEKGNEEPLS 898



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 51/208 (24%), Positives = 86/208 (41%), Gaps = 22/208 (10%)

Query: 58  AKKRKTQDKQPQEPAPKRKPFAVKADSSSV-----DECDDSDGTEDMDEKEEDEGEEYSE 112
           A+ +   + +P+E  P + P AV    + V     D+ ++  G ED+ E E         
Sbjct: 702 AQPQAKAESKPEEEEPAKLP-AVTVTPAPVPDIKGDQKENPGGQEDVAEAEST------- 753

Query: 113 DNDEPGDEDEEDEEGDREEEEEIEEEDEDDDE-----DGEDVEDEEEEE---EEEEEEEE 164
             + PG+E E   EG+ EE+   E + E + E      GE+ EDE E E   + E E+E 
Sbjct: 754 -GEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEG 812

Query: 165 EEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESE 224
           E   ED +M  +           +N+ +  ++   +      + G   E+       E E
Sbjct: 813 EIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEE 872

Query: 225 MNSNTSNSLEDDSDKNENLGRKSELSLD 252
                    E++ ++ E  G +  LSLD
Sbjct: 873 EEEEEQEEEEEEEEEEEEKGNEEPLSLD 900


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 46/95 (48%), Positives = 59/95 (62%), Gaps = 14/95 (14%)

Query: 89  ECDDSDG---TEDMDEKEEDEGEE-YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD- 143
           E  DSD     E +D++EEDE EE Y ED     DE++EDEE + EEE+   EE+ED++ 
Sbjct: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEG 213

Query: 144 -EDGEDVEDEEEEEEEEEEE-------EEEEENED 170
             DGE V+DEE+EEE  EEE       E E+E ED
Sbjct: 214 YNDGE-VDDEEDEEELGEEERGQKRKREPEDEGED 247



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 38/101 (37%), Positives = 60/101 (59%), Gaps = 9/101 (8%)

Query: 98  DMDEKE--EDEGEEYSED-NDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEE 154
           D D+KE  + + E Y E  +DE  DEDEE+ + D +  E+ E+EDE+++ + EDV  EEE
Sbjct: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208

Query: 155 EEE------EEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189
           E+E      E ++EE+EEE  + +      R  +D  +DD+
Sbjct: 209 EDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 34/88 (38%), Positives = 54/88 (61%), Gaps = 6/88 (6%)

Query: 87  VDECDDSDGTEDMDEKEEDEG---EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE-DD 142
           V+  DD +  ED +E +ED     +E  ED +E G  +EED  G+ EE+EE   + E DD
Sbjct: 164 VEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEG--EEEDVSGEEEEDEEGYNDGEVDD 221

Query: 143 DEDGEDVEDEEEEEEEEEEEEEEEENED 170
           +ED E++ +EE  ++ + E E+E E++D
Sbjct: 222 EEDEEELGEEERGQKRKREPEDEGEDDD 249



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 37/86 (43%), Positives = 47/86 (54%), Gaps = 9/86 (10%)

Query: 110 YSEDNDEPGDEDEED--EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167
           Y  D+ E  D D E   E  D EEE+E EEE ++D +  ED EDE+EEEE EEE+   EE
Sbjct: 148 YDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEE 207

Query: 168 NEDHQMNCHNTRIMQDTEKDDNNNDE 193
            ED +          D E DD  ++E
Sbjct: 208 EEDEEG-------YNDGEVDDEEDEE 226



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 21/80 (26%), Positives = 43/80 (53%)

Query: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180
           D +D+E    + E   E  +D++ED ++ E +E+ +  E+EE+E+EE E  + +      
Sbjct: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208

Query: 181 MQDTEKDDNNNDEYDNYDEL 200
             +   +D   D+ ++ +EL
Sbjct: 209 EDEEGYNDGEVDDEEDEEEL 228



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 19/66 (28%), Positives = 39/66 (59%)

Query: 83  DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142
           D+  V++ +D D  E+ +E++    EE  E+    G+ D+E++E +  EEE  ++   + 
Sbjct: 182 DAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREP 241

Query: 143 DEDGED 148
           +++GED
Sbjct: 242 EDEGED 247



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 20/79 (25%), Positives = 46/79 (58%), Gaps = 5/79 (6%)

Query: 126 EGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE-----EEEEEENEDHQMNCHNTRI 180
           +G   +++E  + D +   +G D E+E+E+EEE +E     E+EE+E+E+ +    +   
Sbjct: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205

Query: 181 MQDTEKDDNNNDEYDNYDE 199
            ++ +++  N+ E D+ ++
Sbjct: 206 EEEEDEEGYNDGEVDDEED 224



 Score = 33.9 bits (76), Expect = 0.94
 Identities = 20/104 (19%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 145 DGEDVEDEEEEEEEEE-------EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNY 197
           DG D +D+E  + + E       +EEE+E+ E++  +       +D ++++   +E  + 
Sbjct: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205

Query: 198 DELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241
           +E   +   N G++ ++       E E         ED+ + ++
Sbjct: 206 EEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249


>gi|21735569 claspin [Homo sapiens]
          Length = 1339

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 35/104 (33%), Positives = 64/104 (61%)

Query: 66  KQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE 125
           K   + A K + F  +    ++ + D+ DG E+ +E+EE+  +E  ED +E  +++E++E
Sbjct: 598 KAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEE 657

Query: 126 EGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169
           E + EEE+E EEE+E + E  E +   EE E ++E+E ++E N+
Sbjct: 658 ELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKENND 701



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 46/151 (30%), Positives = 72/151 (47%), Gaps = 9/151 (5%)

Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ------M 173
           ++E+  E + EEEEE+ +E E+D E+  + E++EEE EEEEE+EEEEE E +Q      +
Sbjct: 623 DNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLL 682

Query: 174 NCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSL 233
           +        + E D  NND      + V    L++ K     +     +   +       
Sbjct: 683 SSEEIETKDEKEMDKENNDGSSEIGKAV--GFLSVPKSLSSDSTLLLFKDSSSKMGYFPT 740

Query: 234 EDDSDKNENLGRKSELSLDLDSDVVRETVDS 264
           E+ S+ +EN G K    LD D      T +S
Sbjct: 741 EEKSETDENSG-KQPSKLDEDDSCSLLTKES 770



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 52/232 (22%), Positives = 93/232 (40%), Gaps = 33/232 (14%)

Query: 43   SGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEK 102
            SGK+    +    P + +   Q+K+     P  +  A+ + S   D+ ++ +  E  D +
Sbjct: 945  SGKFTSQDA--STPASSELNKQEKESSMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFR 1002

Query: 103  EEDEGEEYSEDNDEPGDEDE----EDEEGDREEE-----EEIEEE-------DEDDDEDG 146
                  E+  D DE  D       ED E D EEE     E+++ +       +++ +  G
Sbjct: 1003 LVSNDNEFDSDEDEHSDSGNDLALEDHEDDDEEELLKRSEKLKRQMRLRKYLEDEAEVSG 1062

Query: 147  EDVEDEEEEEEEEEEEEEEEENE-----DHQMNCHNTRIMQDTEKDDNNNDEYDNYDELV 201
             DV  E+E + EE +E EE+  +     D ++     +I   T  DD+          L 
Sbjct: 1063 SDVGSEDEYDGEEIDEYEEDVIDEVLPSDEELQSQIKKIHMKTMLDDDKRQL-----RLY 1117

Query: 202  AKSLLNLGKIAEDAAYRARTESEMNSNTSNSL-----EDDSDKNENLGRKSE 248
             +  L  G +  D   R R     N + ++ +     + D D+ E    +SE
Sbjct: 1118 QERYLADGDLHSDGPGRMRKFRWKNIDDASQMDLFHRDSDDDQTEEQLDESE 1169



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 31/147 (21%), Positives = 57/147 (38%), Gaps = 17/147 (11%)

Query: 112 EDNDEPGDEDEED-------EEGDREEEEEIEEED------EDDDEDGEDVEDEEEEEEE 158
           E+ D P D  +          EGD +EE  + ++       +D D + ED     E+   
Sbjct: 22  EEADSPSDSGQGSYETIGPLSEGDSDEEIFVSKKLKNRKVLQDSDSETEDTNASPEKTTY 81

Query: 159 EEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYR 218
           +  EEE +EN     N    RI +     D +  E   Y E +   +    K   + + +
Sbjct: 82  DSAEEENKENLYAGKNTKIKRIYKTVADSDESYMEKSLYQENLEAQV----KPCLELSLQ 137

Query: 219 ARTESEMNSNTSNSLEDDSDKNENLGR 245
           +   ++  ++  +S +   DK    G+
Sbjct: 138 SGNSTDFTTDRKSSKKHIHDKEGTAGK 164



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 39/167 (23%), Positives = 66/167 (39%), Gaps = 19/167 (11%)

Query: 93   SDGTEDMDEKEE-DEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVED 151
            SD  E+M+E      G+  S+D   P   +          ++E E    D  E+   +  
Sbjct: 931  SDKKENMEELLNLCSGKFTSQDASTPASSELN--------KQEKESSMGDPMEEALALCS 982

Query: 152  EEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNND------EYDNYDELVAKSL 205
                 ++EEE+EEEE  +   ++  N     + E  D+ ND      E D+ +EL+ +S 
Sbjct: 983  GSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDEHSDSGNDLALEDHEDDDEEELLKRS- 1041

Query: 206  LNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLD 252
                K+      R   E E   + S+   +D    E +    E  +D
Sbjct: 1042 ---EKLKRQMRLRKYLEDEAEVSGSDVGSEDEYDGEEIDEYEEDVID 1085



 Score = 30.8 bits (68), Expect = 8.0
 Identities = 17/78 (21%), Positives = 42/78 (53%), Gaps = 2/78 (2%)

Query: 69  QEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEE-DEGEEYSEDNDEPGDEDEEDEEG 127
           +E   + +    +++    ++ +  +  E+++E+EE +E EE  E N E  +     EE 
Sbjct: 629 EEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEE-EEEEEGNQETAEFLLSSEEI 687

Query: 128 DREEEEEIEEEDEDDDED 145
           + ++E+E+++E+ D   +
Sbjct: 688 ETKDEKEMDKENNDGSSE 705


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 40/125 (32%), Positives = 65/125 (52%), Gaps = 21/125 (16%)

Query: 96  TEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE---DEDDDEDGEDVEDE 152
           T  +  + E+E EE  E+ +E G+ +EE+EEG+ EEEE  E E   +E++ E+  DV+ +
Sbjct: 398 TTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSD 457

Query: 153 EEEEEEEEEEEEEEENED------------------HQMNCHNTRIMQDTEKDDNNNDEY 194
           EEEEE+EE   E  E ED                   +  C     ++  E  D++++E 
Sbjct: 458 EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517

Query: 195 DNYDE 199
           D+ +E
Sbjct: 518 DDEEE 522



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 46/142 (32%), Positives = 75/142 (52%), Gaps = 11/142 (7%)

Query: 104 EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEE 163
           + EGEE  E+     +E+EE+EEG+ EEEEE  EE+E++  +GE++ +EEE EEE + + 
Sbjct: 402 KSEGEEEEEE-----EEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDS 456

Query: 164 EEEENEDHQMNCHNTRI---MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRAR 220
           +EEE ED + +          Q   +   +   Y   +E    +L  L +  ED+   + 
Sbjct: 457 DEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL-EGGEDS--DSD 513

Query: 221 TESEMNSNTSNSLEDDSDKNEN 242
           +E E +    +  EDD D  E+
Sbjct: 514 SEEEDDEEEDDEDEDDDDDEED 535



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 27/138 (19%)

Query: 59  KKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPG 118
           K    ++++ +E   + +    + +    +E ++    E++ E+EE E EE   D+DE  
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVE-EEGDVDSDEEE 460

Query: 119 DEDEEDEEGDREEEEEIE--------------------------EEDEDDDEDGEDVEDE 152
           +EDEE      E E+  +                          E  ED D D E+ +DE
Sbjct: 461 EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDE 520

Query: 153 EEEEEEEEEEEEEEENED 170
           EE++E+E+++++EE+ ++
Sbjct: 521 EEDDEDEDDDDDEEDGDE 538



 Score = 38.9 bits (89), Expect = 0.029
 Identities = 18/44 (40%), Positives = 29/44 (65%), Gaps = 9/44 (20%)

Query: 106 EGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDV 149
           EG E S+ + E  D++EED+E         +E+D+DD+EDG++V
Sbjct: 505 EGGEDSDSDSEEEDDEEEDDE---------DEDDDDDEEDGDEV 539


>gi|21361639 DIPB protein [Homo sapiens]
          Length = 344

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 42/111 (37%), Positives = 60/111 (54%), Gaps = 5/111 (4%)

Query: 93  SDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152
           +DG     E+ E + E+  E   E G+E E +EE + EEE E EEE E D+ D E  ED 
Sbjct: 71  ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESE-DESDEESEEDS 129

Query: 153 EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203
           EEE E+E+E E EE+N++       +    +TE +   + E +   E VAK
Sbjct: 130 EEEMEDEQESEAEEDNQEE----GESEAEGETEAESEFDPEIEMEAERVAK 176



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 31/75 (41%), Positives = 46/75 (61%)

Query: 92  DSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVED 151
           +S+  E+ + +EE E EE SE  +E  DE +E+ E D EEE E E+E E ++++ E+ E 
Sbjct: 92  ESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGES 151

Query: 152 EEEEEEEEEEEEEEE 166
           E E E E E E + E
Sbjct: 152 EAEGETEAESEFDPE 166



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 34/79 (43%), Positives = 48/79 (60%), Gaps = 3/79 (3%)

Query: 91  DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVE 150
           ++S+  E+ + +EE E EE SED  E  +E EED E + E+E+E E E ED+ E+GE   
Sbjct: 97  EESESEEESESEEESETEEESED--ESDEESEEDSEEEMEDEQESEAE-EDNQEEGESEA 153

Query: 151 DEEEEEEEEEEEEEEEENE 169
           + E E E E + E E E E
Sbjct: 154 EGETEAESEFDPEIEMEAE 172



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 13/127 (10%)

Query: 58  AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117
           A K + + K  QE    R+  +   + S  +E  +S+   + +E+ EDE +E SE++ E 
Sbjct: 76  AGKEEAEVKVEQE----REIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131

Query: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN--------- 168
             EDE++ E + + +EE E E E + E   + + E E E E   + +  ++         
Sbjct: 132 EMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQ 191

Query: 169 EDHQMNC 175
           ED Q+ C
Sbjct: 192 EDRQLIC 198



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE-EEEEEEEEEEENEDHQMNCHNTRI 180
           +E+ E   E+E EIE E  ++ E  E+ E EEE E EEE E+E +EE+E+          
Sbjct: 78  KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137

Query: 181 MQDTEKDDNNNDEYDNYDELVAKS 204
             + E+D+    E +   E  A+S
Sbjct: 138 ESEAEEDNQEEGESEAEGETEAES 161


>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
          Length = 406

 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 39/83 (46%), Positives = 57/83 (68%), Gaps = 4/83 (4%)

Query: 97  EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156
           E+ +EK+ D+ EEY ++  +  +  EE+EE + +EEEE+E+E+E++ E+ E VE+ EEE 
Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVE-DEEEEVEDEEEEEVEEAEYVEEGEEEL 335

Query: 157 EEEE-EEEEE--EENEDHQMNCH 176
           EEEE EEEEE  EENE      H
Sbjct: 336 EEEELEEEEEVLEENEQRGEEFH 358



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 10/97 (10%)

Query: 77  PFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIE 136
           P  V+ +    ++ ++    E  D KE  E EE  ED +E  +++EE+E  + E  EE E
Sbjct: 273 PLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGE 332

Query: 137 EEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQM 173
           EE          +E+EE EEEEE  EE E+  E+  +
Sbjct: 333 EE----------LEEEELEEEEEVLEENEQRGEEFHL 359



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 6/80 (7%)

Query: 108 EEYSEDNDEPGDEDEEDEEG-DREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEE 166
           EE  + ND   DE+E D+E  D +E  E EEE ED++E+ ED  +EEEE EE E  EE E
Sbjct: 278 EEEEKKND---DEEEYDQEVCDAKEASEEEEEVEDEEEEVED--EEEEEVEEAEYVEEGE 332

Query: 167 ENEDHQMNCHNTRIMQDTEK 186
           E  + +       ++++ E+
Sbjct: 333 EELEEEELEEEEEVLEENEQ 352



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 5/81 (6%)

Query: 122 EEDEEGDREEEEEIEEE---DEDDDEDGEDVEDEEEE--EEEEEEEEEEEENEDHQMNCH 176
           EE+EE   ++EEE ++E    ++  E+ E+VEDEEEE  +EEEEE EE E  E+ +    
Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336

Query: 177 NTRIMQDTEKDDNNNDEYDNY 197
              + ++ E  + N    + +
Sbjct: 337 EEELEEEEEVLEENEQRGEEF 357



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 22/56 (39%), Positives = 34/56 (60%)

Query: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
           P  E+ +       EEEE ++ D++++ D E  + +E  EEEEE E+EEEE ED +
Sbjct: 263 PNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 6/90 (6%)

Query: 56  PLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND 115
           PL  + + + K   E    ++    K  S   +E +D +   + +E+EE E  EY E+  
Sbjct: 273 PLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEG- 331

Query: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDED 145
                +EE EE + EEEEE+ EE+E   E+
Sbjct: 332 -----EEELEEEELEEEEEVLEENEQRGEE 356



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 31/126 (24%)

Query: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEY 194
           +EEE+E  ++D E+ + E  + +E  EEEEE E+E+ +        ++D E+++      
Sbjct: 276 VEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEE--------VEDEEEEE------ 321

Query: 195 DNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLD 254
                             E+A Y    E E+        E+  ++NE  G +  L L++ 
Sbjct: 322 -----------------VEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMP 364

Query: 255 SDVVRE 260
             +  E
Sbjct: 365 LSIFVE 370


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 112/657 (17%), Positives = 217/657 (33%), Gaps = 35/657 (5%)

Query: 81   KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED-----EEDEEGDREEEEEI 135
            K+DSS  D  D S+ ++  D  + D  +  S  + +  D D     + D        +  
Sbjct: 546  KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605

Query: 136  EEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNN---- 191
            +  D  D  D  D  D + +  + E +  + +++    + +++    +++  D++N    
Sbjct: 606  DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665

Query: 192  ----DEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNS-LEDDSDKNENLGRK 246
                D  D+ D   +    N    ++ +     +ES  +S++S+S   D SD + +    
Sbjct: 666  SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 247  SELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSR----NMNYVML 302
            S+ S   DS     + DS       +    S++ +  N +DS    DS     + N    
Sbjct: 726  SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785

Query: 303  GKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVR 362
                N+         SD      S +   +   D +     +N  + +   N +      
Sbjct: 786  NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845

Query: 363  PEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEE 422
               D    +   N SD  N        S  S    S    D     D + +S +SD S+ 
Sbjct: 846  DSSD-GSDSDSSNRSDSSN-------SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897

Query: 423  VFDMTKGNLTLLEKAIALETERAKAMRE--KMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 480
                   +      + + ++  +    E    +  +   D+  S +              
Sbjct: 898  SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957

Query: 481  KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 540
             SSDS       D + ++  +S   +   D +           S S          +   
Sbjct: 958  NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017

Query: 541  MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 600
              +S     +   +     + + +S  S      + +   + + +   S D S SS +SD
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077

Query: 601  RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 660
                        E       +N   ++  S+ +   +    +    +S  +++      +
Sbjct: 1078 S-------SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130

Query: 661  PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSS 717
                + D S            D S SS S+ S   S SS+ S    SS SS  S SS
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 106/637 (16%), Positives = 215/637 (33%), Gaps = 33/637 (5%)

Query: 82   ADSSSVDECDDSDGTEDMDEKEED-EGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE 140
            +DS   ++ DDSD T D +  + +  G   ++DND+      + +  D +  +     D 
Sbjct: 505  SDSKGAED-DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDS 563

Query: 141  DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDEL 200
             D  D +  +     + +  + +  + ++    +  N+    D+    +++D  D+ D  
Sbjct: 564  SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSD-- 621

Query: 201  VAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRE 260
               S  +  K   D+     ++S+  S++S+S   DS  N +    S  S   DS    +
Sbjct: 622  ---SKSDSSKSESDS-----SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673

Query: 261  TVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDE 320
            + DS       +    S++ +  N ++S    DS + +        N+         SD 
Sbjct: 674  SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS-------NSSDS 726

Query: 321  EVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDML 380
            +   SS     +   D +     +N  + +   + +         D    +   N SD  
Sbjct: 727  DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786

Query: 381  NLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIAL 440
            +     +     +   +S + +        D+ S NS  S    D +  + +      + 
Sbjct: 787  DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS------SD 840

Query: 441  ETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKSSDSHVKKPYYDPSRTEKK 500
             ++ + +     +  + R D+  S +               SSDS+      D S +   
Sbjct: 841  SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900

Query: 501  ESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVN 560
                 +   + +           S S     +    +     +S     +   +   + +
Sbjct: 901  SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960

Query: 561  SNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYR 620
             + NS  S S    + +   + + +   S D S SS +SD            +       
Sbjct: 961  DSSNSSDS-SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS-------SNSSDSSDSSDS 1012

Query: 621  NNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYC 680
            ++   ++  SN +        +    +S  + +      +    + D S           
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072

Query: 681  KDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSS 717
             D S SS S+ S   S SSN S    SS SS  S SS
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 113/656 (17%), Positives = 229/656 (34%), Gaps = 62/656 (9%)

Query: 71   PAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEED-EGEEYSEDNDEPGDED---EEDEE 126
            P  K +P   K   S+     +SDG +  D  ++  +G++ +  ++  G++D   E D  
Sbjct: 426  PGQKSEP-GNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNN 484

Query: 127  GDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEK 186
                 +     ++  D+ +G D +  E+++ +   +    ++  +  N ++     D+ K
Sbjct: 485  SSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK 544

Query: 187  DDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRK 246
              +++ + D+ D   +    +        +  +      +S++S+S + DS  + N    
Sbjct: 545  GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604

Query: 247  SELSLDLD----SDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYVML 302
            S+ S   D    SD      DS K  +         + +D N +DS    DS + +    
Sbjct: 605  SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS---- 660

Query: 303  GKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVR 362
                N+       + SD     SS +   +         S  +    N  ++ +      
Sbjct: 661  ----NSSNSSDSSDSSDSSDSSSSSDSSNSSD-------SSDSSDSSNSSESSDSSDSSD 709

Query: 363  PEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEE 422
             +      + + N SD  +    +   S  S   +  +      +  D + S NS  S +
Sbjct: 710  SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769

Query: 423  VFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKS 482
              D +  + +      +  ++   +     + ++    +  +  D S      +     S
Sbjct: 770  SSDSSDSSDS------SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823

Query: 483  SDSHVKKPYYDPSR-TEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAM 541
            SDS       D S  ++  +S   + G D           +RS S          +    
Sbjct: 824  SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS-------SNRSDSSNSSDSSDSSDSSNS 876

Query: 542  HESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDR 601
             +S     +   +     + + NS  S S    + +   + + +   S D S+SS +SD 
Sbjct: 877  SDSSDSSDSNESSNSSDSSDSSNSSDSDS----SDSSNSSDSSDSSNSSDSSESSNSSD- 931

Query: 602  VLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAP 661
                               N+  + +  S+ + +    S +S   NS D+      + + 
Sbjct: 932  -------------------NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972

Query: 662  KVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSS 717
               + D S            D S SS S++S   S SS+ S    SS SS  S SS
Sbjct: 973  SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 27/173 (15%), Positives = 68/173 (39%), Gaps = 2/173 (1%)

Query: 84   SSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD 143
            S S +  D SD ++  D  +     + S+ ++     D  D     +  +  +  D  D 
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177

Query: 144  EDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203
             +  D  D  +  +  +  +  + ++    +  ++    D+    +++D  D+ D   + 
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSDSSDSSDSSDSNESS 1235

Query: 204  SLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSD 256
               +    ++ +     ++S  +S++++   D+SD     G  +    D DSD
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 23/115 (20%), Positives = 47/115 (40%), Gaps = 2/115 (1%)

Query: 84   SSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD 143
            S S D  D SD ++  D  +  +  + S+ +D     D  D     E  +  +  D  D 
Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246

Query: 144  EDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKD--DNNNDEYDN 196
             +  D  D  +  +   +  +E +++    N +N     D++ +  D+N+   D+
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 128/678 (18%), Positives = 223/678 (32%), Gaps = 94/678 (13%)

Query: 91  DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEE-EEIEEEDEDDDEDGEDV 149
           D+SDG+   +  +EDE E   +D DE     ++     + +E ++  +ED+ D   G++ 
Sbjct: 240 DNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNS 299

Query: 150 EDEEEEEEEEEEE----------EEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
           + +E  + E +E+           + EEN       + ++ ++DT+K   N+ E    + 
Sbjct: 300 DSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQK--LNHRESKRVEN 357

Query: 200 LVAKSLLN--LGKIAEDAAYRARTESEMNSNTSNSL----EDDSDKN------------- 240
            + K      +GK ++D     +  S  N N +  +    E   DK              
Sbjct: 358 RITKESETHAVGK-SQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKT 416

Query: 241 -------ENLGRKSE---------LSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRN 284
                  E  G+KSE            D +SD   ++ D      QG     S+  N  +
Sbjct: 417 QGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGY-DSYDFDDKSMQGDDPNSSDESNGND 475

Query: 285 YADSMSQQDSRNMNYVML----GKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARK 340
            A+S S  +S +           K   NG   K  E+ D +                   
Sbjct: 476 DANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD------------------S 517

Query: 341 LSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCA 400
            S+TN  + N   N          +D       +  SD  +    +   S  S   +   
Sbjct: 518 TSDTNNSDSNGNGN-------NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD 570

Query: 401 KEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRD 460
             D     D D++  +S  S +       N      + + ++  +    +       + D
Sbjct: 571 SSDSNSSSDSDSSDSDSSDSSDSDSSDSSN-----SSDSSDSSDSSDSSDSSDSSDSKSD 625

Query: 461 NMRSYEDQSPRQLPGEDRKPKSSDSHVKKPYYDPSR-TEKKESKCPTPGCDGTGHVTGLY 519
           + +S  D S      +     SSDS       D S  +   +S   +   D +       
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685

Query: 520 PHHRSLSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEK 579
               S S          +     +S     +         + + NS  S      + +  
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745

Query: 580 LAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKY 639
            + +     S D S SS +SD            +       +N   +   SN + +    
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDS-------SDSSDSSDSSDSSNSSDSNDSSN-SSDSSDS 797

Query: 640 SKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSS 699
           S +S   NS D+      + +    + D S    D +       S  SS +S  + S SS
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSD-SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856

Query: 700 NLSCGGGSSASSTCSKSS 717
           N S    SS SS  S SS
Sbjct: 857 NRSDSSNSSDSSDSSDSS 874



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 32/156 (20%), Positives = 72/156 (46%), Gaps = 18/156 (11%)

Query: 104 EDEGEEYSEDNDEPGDEDEEDEE--GDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE 161
           ED G + S+ +      DE+++E  GD E+EE    +D  ++  G++ +D  +E++ +  
Sbjct: 235 EDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSS 294

Query: 162 EEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAED-AAYRAR 220
             +  +++++           D E  ++ ++E D   +  +KS  N   I ED  + R  
Sbjct: 295 IGQNSDSKEY----------YDPEGKEDPHNEVDG--DKTSKSEENSAGIPEDNGSQRIE 342

Query: 221 TESEMNSNTSNSLEDDSDKNEN---LGRKSELSLDL 253
              ++N   S  +E+   K      +G+  +  +++
Sbjct: 343 DTQKLNHRESKRVENRITKESETHAVGKSQDKGIEI 378



 Score = 38.1 bits (87), Expect = 0.050
 Identities = 17/84 (20%), Positives = 34/84 (40%), Gaps = 2/84 (2%)

Query: 82   ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDED 141
            +DSS     D SD  E  D  +  +  + S  +D     D  D   D  +E + + +  +
Sbjct: 1220 SDSSDSS--DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277

Query: 142  DDEDGEDVEDEEEEEEEEEEEEEE 165
             + +G D + + E  +      ++
Sbjct: 1278 GNNNGSDSDSDSEGSDSNHSTSDD 1301



 Score = 37.4 bits (85), Expect = 0.085
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 95  GTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG----DREEEEEIEEEDEDDDEDGEDVE 150
           G ++ D      G +  ED     DEDEE   G    +  + +E ++  ++DD D    +
Sbjct: 238 GLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQ 297

Query: 151 DEEEEEEEEEEEEEEEENE 169
           + + +E  + E +E+  NE
Sbjct: 298 NSDSKEYYDPEGKEDPHNE 316


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 39/110 (35%), Positives = 58/110 (52%), Gaps = 7/110 (6%)

Query: 91  DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGD--REEEEEIEEEDEDDDEDGED 148
           D SD        E    E  S   +E  +E+EE+EEG    E EEE EEE+E+++E G +
Sbjct: 256 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 315

Query: 149 VED-----EEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193
            E+      EE  EEE  E+EE ENE+H +    +R  +D+ + +   +E
Sbjct: 316 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 365



 Score = 64.3 bits (155), Expect = 7e-10
 Identities = 51/188 (27%), Positives = 83/188 (44%), Gaps = 17/188 (9%)

Query: 47  ARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDE--CDDSDGTEDMDEKEE 104
           A HR++     + K K        P P R+ F +      V E   ++ D   D+ +  +
Sbjct: 201 AHHRTMRE-DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD 259

Query: 105 DEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEE 164
            E +  S        E    E G   EEEE  EE+E+++E+G   E+ EEEEEEEEEEEE
Sbjct: 260 SERKTSSA-------ESSSAESGSGSEEEE--EEEEEEEEEGSTSEESEEEEEEEEEEEE 310

Query: 165 EEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESE 224
           E  +   + +  +   + + E  ++   E +N+  +V +S     +   D+      E E
Sbjct: 311 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES-----RFDRDSGESEEAEEE 365

Query: 225 MNSNTSNS 232
           +   T  S
Sbjct: 366 VGEGTPQS 373



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 41/186 (22%), Positives = 77/186 (41%), Gaps = 19/186 (10%)

Query: 59  KKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPG 118
           K R+ Q +Q ++   +R+    + +  +  E      T   D  ++ +   +S     P 
Sbjct: 168 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 227

Query: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE-----------EEEEEEEEEEEEEE 167
            E  E  +G +  +EE + E+ D   D +D+ D E           E     EEEEEEEE
Sbjct: 228 RERFELGDGRKPVKEE-KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 286

Query: 168 NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNS 227
            E+ + +       ++ E+++   +   N +E   +S       AE+ +    +E E   
Sbjct: 287 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-------AEEVSEEEMSEDEERE 339

Query: 228 NTSNSL 233
           N ++ L
Sbjct: 340 NENHLL 345



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 68/371 (18%), Positives = 125/371 (33%), Gaps = 33/371 (8%)

Query: 97  EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGD-------REEEEEIEEEDEDDDEDGEDV 149
           ++ +EK E +  + S+D D   D  EE E  D       R      E+  ED  E+ + +
Sbjct: 24  KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83

Query: 150 EDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQ-DTEKDDNNNDEYDNYDELVAKSLLNL 208
             +  ++   +E+    ++E  +    + R+ + + E+   + +E D      A+     
Sbjct: 84  AIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDK-----ARREWER 138

Query: 209 GKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLL 268
            K  E A   +R E +         E +    E    + E          R      +  
Sbjct: 139 QKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 198

Query: 269 AQGHGVVLSENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLE 328
              H   + E+ +D+  A   S+   R          + +G      E+ +E   LS L+
Sbjct: 199 VSAHHRTMREDYSDKVKASHWSRSPPRPPRERF---ELGDGRKPVKEEKMEERDLLSDLQ 255

Query: 329 CLRNQCFDLARKLSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDMLNLMRLEEQ 388
            +     D  RK S                +    EE+  G T + +  +       EE+
Sbjct: 256 DIS----DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311

Query: 389 LSPRSRVFASCAKEDGCHERDDDTTSVNSDRS---------EEVFDMTKGNLTLLEKAIA 439
               S      A E    E  ++  S + +R          E  FD   G     E+ + 
Sbjct: 312 TGSNSEE----ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVG 367

Query: 440 LETERAKAMRE 450
             T ++ A+ E
Sbjct: 368 EGTPQSSALTE 378



 Score = 30.8 bits (68), Expect = 8.0
 Identities = 51/306 (16%), Positives = 111/306 (36%), Gaps = 34/306 (11%)

Query: 51  SVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTED-----MDEKEED 105
           ++   P  ++   +D+  ++ +   KP    +    V    D    E      + E+E +
Sbjct: 61  TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE 120

Query: 106 EGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEE 165
             + + E+ D+   E E  +  +   E    E D  +  + +   + +  E+++E+ E++
Sbjct: 121 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK 180

Query: 166 E----------ENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLG------ 209
           E          E E  +    + R M++   D      +        +    LG      
Sbjct: 181 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 240

Query: 210 --------KIAEDAAYRARTESEMNSNTSNSLEDDS----DKNENLGRKSELSLDLDSDV 257
                    +  D    + +E + +S  S+S E  S    ++ E    + E S   +S+ 
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300

Query: 258 VRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSR-NMNYVMLGKPMNNGLMEKMVE 316
             E  +  +     +    SE   +    + MS+ + R N N++++             E
Sbjct: 301 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 360

Query: 317 ESDEEV 322
           E++EEV
Sbjct: 361 EAEEEV 366


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.127    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,394,195
Number of Sequences: 37866
Number of extensions: 2860871
Number of successful extensions: 99929
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1258
Number of HSP's successfully gapped in prelim test: 753
Number of HSP's that attempted gapping in prelim test: 25512
Number of HSP's gapped (non-prelim): 26751
length of query: 1184
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1071
effective length of database: 13,968,660
effective search space: 14960434860
effective search space used: 14960434860
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press