BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|60498973 myelin transcription factor 1-like [Homo sapiens] (1184 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|60498973 myelin transcription factor 1-like [Homo sapiens] 2420 0.0 gi|17975763 myelin transcription factor 1 [Homo sapiens] 985 0.0 gi|7662168 suppression of tumorigenicity 18 [Homo sapiens] 759 0.0 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 84 8e-16 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 84 8e-16 gi|55956788 nucleolin [Homo sapiens] 82 2e-15 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 81 5e-15 gi|4503257 death-domain associated protein isoform a [Homo sapiens] 79 3e-14 gi|215422388 death-domain associated protein isoform a [Homo sap... 79 3e-14 gi|215422366 death-domain associated protein isoform b [Homo sap... 79 3e-14 gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 77 1e-13 gi|115529449 upstream binding transcription factor, RNA polymera... 75 4e-13 gi|115529451 upstream binding transcription factor, RNA polymera... 75 4e-13 gi|7657671 upstream binding transcription factor, RNA polymerase... 75 4e-13 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 74 8e-13 gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 73 1e-12 gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 73 1e-12 gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 73 1e-12 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 73 2e-12 gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 72 2e-12 gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 72 3e-12 gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 72 3e-12 gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 71 5e-12 gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 70 9e-12 gi|21735569 claspin [Homo sapiens] 70 2e-11 gi|21735415 centromere protein B [Homo sapiens] 69 3e-11 gi|21361639 DIPB protein [Homo sapiens] 69 3e-11 gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 69 3e-11 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 68 5e-11 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 68 6e-11 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 2420 bits (6273), Expect = 0.0 Identities = 1184/1184 (100%), Positives = 1184/1184 (100%) Query: 1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK Sbjct: 1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60 Query: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE Sbjct: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120 Query: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180 Query: 181 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 240 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN Sbjct: 181 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKN 240 Query: 241 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 300 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV Sbjct: 241 ENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYV 300 Query: 301 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 360 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH Sbjct: 301 MLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQH 360 Query: 361 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 420 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS Sbjct: 361 VRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRS 420 Query: 421 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 480 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP Sbjct: 421 EEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 480 Query: 481 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 540 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA Sbjct: 481 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 540 Query: 541 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 600 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD Sbjct: 541 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 600 Query: 601 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 660 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA Sbjct: 601 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 660 Query: 661 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 720 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY Sbjct: 661 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSSFDY 720 Query: 721 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 780 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP Sbjct: 721 THDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVDENGTLDLSMNKQRP 780 Query: 781 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 840 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE Sbjct: 781 RDSCCPILTPLEPMSPQQQAVMNNRCFQLGEGDCWDLPVDYTKMKPRRIDEDESKDITPE 840 Query: 841 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 900 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE Sbjct: 841 DLDPFQEALEERRYPGEVTIPSPKPKYPQCKESKKDLITLSGCPLADKSIRSMLATSSQE 900 Query: 901 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 960 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ Sbjct: 901 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 960 Query: 961 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 1020 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF Sbjct: 961 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 1020 Query: 1021 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1080 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM Sbjct: 1021 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1080 Query: 1081 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1140 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP Sbjct: 1081 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1140 Query: 1141 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV Sbjct: 1141 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 985 bits (2547), Expect = 0.0 Identities = 586/1244 (47%), Positives = 758/1244 (60%), Gaps = 183/1244 (14%) Query: 1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60 M ++ E+KR RTRSK +R P E +L SCPTPGC GSGHV GKY+RHRS+ CPLAKK Sbjct: 1 MSLENEDKRARTRSKALRGPPETTAADL-SCPTPGCTGSGHVRGKYSRHRSLQSCPLAKK 59 Query: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120 RK + + + KRK +K DEG Y D+D G E Sbjct: 60 RKLEGAEAEHLVSKRKSHPLKLAL--------------------DEG--YGVDSD--GSE 95 Query: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180 D E ++ +E E E + + G+D E E E + + + I Sbjct: 96 DTEVKDASVSDESEGTLEGAEAETSGQD---------EIHRPETAEGRSPVKSHFGSNPI 146 Query: 181 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRART--ESEMNSNTSNSLEDDSD 238 T ++ Y +Y ++A SLLNLG+IAE+ ++ + L++ ++ Sbjct: 147 GSATA---SSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAE 203 Query: 239 KNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMN 298 + + E L + + E V+ S+++ ++ D+ S++ S+ Sbjct: 204 GAAS--EEGEKGLFIQPEDAEEVVEVT--------TERSQDLCPQSLEDAASEESSKQKG 253 Query: 299 YVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIR 358 + + E+ EE DEE + + + E +E ++ Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEE---------EEEEEEEEEEEEEEEEEEEEEEEEEEEE 304 Query: 359 QHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSR--VFASCAKEDGCHERDDDTTSVN 416 + P+ F T + L R E SP+ V +D ++D+DT S Sbjct: 305 EEAAPDVIFQEDTSHTSAQKAPEL-RGPESPSPKPEYSVIVEVRSDD---DKDEDTHSRK 360 Query: 417 S---DRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQL 473 S D SE MT+GNL LLE+AIAL+ E+ + + E A +QS L Sbjct: 361 STVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPA----------EQSQLGL 410 Query: 474 --PGEDRKPKSSDSHVKKPYY--DPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCP 529 PG+ KP + V+K YY DPSR EK+E KCPTPGCDGTGHVTGLYPHHRSLSGCP Sbjct: 411 GEPGKAAKPLDT---VRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCP 467 Query: 530 HKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKH-- 587 HKDR+PPEILAMHE+VLKCPTPGCTG+GHVNSNRN+HRSLSGCPIAAAEKLAK+ EK Sbjct: 468 HKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQP 527 Query: 588 QSCDVSKSSQASDRVLRPMCFVKQLEIPQYG-YRNNVPTTTPRSNLAKELEKYSKTSFEY 646 Q+ D SKSS SDR+LRPMCFVKQLE+P YG YR NV TPR+NLAKELEK+SK +F+Y Sbjct: 528 QTGDPSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDY 587 Query: 647 NSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGG 706 S+D +GKR +APK+QT + SPK + Sbjct: 588 ASFDAQVFGKRMLAPKIQTSETSPKAF--------------------------------- 614 Query: 707 SSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVD 766 FDY+ D EAAHMAATAILNLSTRC EMP+NLSTKPQDL +++ D+EVD Sbjct: 615 ---------QCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDL-PSKSVDIEVD 664 Query: 767 ENGTLDLSMNKQRPRDSCCP----------ILTP-----LEPMSPQQQAVMNNRCFQLGE 811 ENGTLDLSM+K R R++ P + +P S ++ + + Q Sbjct: 665 ENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASR 724 Query: 812 GDCWDLPVDYTKMKPRRIDEDESKDITP----------EDLDPFQEALEERRYPGEVTIP 861 D WD P+DYT KP R+ E+E ++ P +D + +E EER+YPGEVT+ Sbjct: 725 QDEWDRPLDYT--KPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLT 782 Query: 862 SPKPKYPQCKESKKDLIT---------------------LSGCPLADKSIRSMLATSSQE 900 + K K+ K+ KK+L+T LSGCPLADKS+R+++A S + Sbjct: 783 NFKLKF-LSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSAD 841 Query: 901 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 960 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSG+++A +K+DKED E ++CPVPGC G Sbjct: 842 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGL 901 Query: 961 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 1020 GHI+GKYASHRSASGCPLAA+RQK+G LNGS FSWKS+K EG +CPTPGCDGSGH +GSF Sbjct: 902 GHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSF 961 Query: 1021 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1080 LTHRSLSGCPRAT A KK KLSG+++L+ K + S+ +ENDEEIKQL++EI++LNESNS+M Sbjct: 962 LTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEM 1021 Query: 1081 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1140 EA M++L++QI++ME NLK IEEENK+IE+QNE+L EL+ LSQ+LI SLANI+LPHM+P Sbjct: 1022 EAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEP 1081 Query: 1141 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184 I EQNFDAYV+TLT+MY+NQD PENK LLE+IKQAVRGIQV Sbjct: 1082 ICEQNFDAYVSTLTDMYSNQD----PENKDLLESIKQAVRGIQV 1121 >gi|7662168 suppression of tumorigenicity 18 [Homo sapiens] Length = 1047 Score = 759 bits (1960), Expect = 0.0 Identities = 424/813 (52%), Positives = 546/813 (67%), Gaps = 80/813 (9%) Query: 407 ERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYE 466 E D ++ +V ++ ++ + KGNL+LLE+AIAL+ ER + + + Sbjct: 280 EEDSESLAVMTEEGSDL-EKAKGNLSLLEQAIALQAERGCVFH----------NTYKELD 328 Query: 467 DQSPRQLPGEDRKPKSSDSHVKKPYYDPS--RTEKKESKCPTPGCDGTGHVTGLYPHHRS 524 L GE R+ K D ++ + + R EK+E+KCP PGCDGTGHVTGLYPHHRS Sbjct: 329 RFLLEHLAGERRQTKVIDMGGRQIFNNKHSPRPEKRETKCPIPGCDGTGHVTGLYPHHRS 388 Query: 525 LSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQ 584 LSGCPHK RVP EILAMHE+VLKCPTPGCTGRGHVNSNRN+HRSLSGCPIAAAEKLA +Q Sbjct: 389 LSGCPHKVRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQ 448 Query: 585 EKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPT---TTPRSNLAKELEKYSK 641 +K+Q D ++ Q D+ R VKQ+E N P+ T+PR+ ++KE EK+ K Sbjct: 449 DKNQ-LDSPQTGQCPDQAHRTS-LVKQIEF-------NFPSQAITSPRATVSKEQEKFGK 499 Query: 642 TSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNL 701 F+Y S+D +GKR + VQ R P + ++K + P+ + PS+ Sbjct: 500 VPFDYASFDAQVFGKRPLIQTVQGRKTPP--FPESKHF-----PNPVKFPNRLPSA---- 548 Query: 702 SCGGGSSASSTCSKSSFDYTHDMEAAHMAATA-ILNLSTRCREMPQNLSTKPQDLCATRN 760 G+ S SS+ Y E H+AA A ILNLSTRCRE LS KPQ L A + Sbjct: 549 ----GAHTQSPGRASSYSYGQCSEDTHIAAAAAILNLSTRCREATDILSNKPQSLHA-KG 603 Query: 761 PDMEVDENGTLDLSMNKQRPRDSCCPILT-----PLEPMSP-QQQAVMNNRCFQ--LGEG 812 ++EVDENGTLDLSM K R D P+ + P SP + +++ N F L + Sbjct: 604 AEIEVDENGTLDLSMKKNRILDKSAPLTSSNTSIPTPSSSPFKTSSILVNAAFYQALCDQ 663 Query: 813 DCWDLPVDYTKMKPRRIDEDESKDITPEDLDPFQEALEERRYPGEVTIPSPKPKYPQCKE 872 + WD P++Y+K + +E E ++ E LEE+++PGE +IPSPKPK ++ Sbjct: 664 EGWDTPINYSKTHGKTEEEKEKDPVSS------LENLEEKKFPGEASIPSPKPKL-HARD 716 Query: 873 SKKDLIT---------------------LSGCPLADKSIRSMLATSSQELKCPTPGCDGS 911 KK+LIT +SGCPLADK+++S++A +SQELKCPTPGCDGS Sbjct: 717 LKKELITCPTPGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGS 776 Query: 912 GHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQGHITGKYASHR 971 GH+TGNYASHRSLSGCPRA+K G+++ +KE+KED E ++CPV GCDGQGHI+GKY SHR Sbjct: 777 GHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPE-LKCPVIGCDGQGHISGKYTSHR 835 Query: 972 SASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSFLTHRSLSGCPR 1031 +ASGCPLAAKRQK+ LNG+ SWK K E CP PGC+G GHV+ F+THRSLSGCP Sbjct: 836 TASGCPLAAKRQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPL 895 Query: 1032 ATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQMEADMIKLRTQI 1091 +KK K+S E+++TIK +A+ GIE+DEEI+ LDEEIKELNESN ++EADM+KL+TQI Sbjct: 896 NAQVIKKGKVS-EELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQI 954 Query: 1092 TTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDPINEQNFDAYVT 1151 T+MESNLKTIEEENK+IEQ NESLL ELA LSQ+LI SLA+IQLP M PI+EQNF+AYV Sbjct: 955 TSMESNLKTIEEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVN 1014 Query: 1152 TLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184 TLT+MY+N +R SPE KALLE+IKQAV+GI V Sbjct: 1015 TLTDMYSNLERDYSPECKALLESIKQAVKGIHV 1047 Score = 65.5 bits (158), Expect = 3e-10 Identities = 27/35 (77%), Positives = 30/35 (85%) Query: 26 QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60 +EL +CPTPGCDGSGHV+G YA HRSV GCPLA K Sbjct: 719 KELITCPTPGCDGSGHVTGNYASHRSVSGCPLADK 753 Score = 60.8 bits (146), Expect = 7e-09 Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 4/55 (7%) Query: 26 QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK---RKTQDKQPQEPAPKRKP 77 QEL CPTPGCDGSGHV+G YA HRS+ GCP A+K + T K+ +E + P Sbjct: 764 QEL-KCPTPGCDGSGHVTGNYASHRSLSGCPRARKGGVKMTPTKEEKEDPELKCP 817 Score = 56.6 bits (135), Expect = 1e-07 Identities = 58/239 (24%), Positives = 88/239 (36%), Gaps = 76/239 (31%) Query: 1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60 M+ + E+K RTRSKG VP++ IQEL Y C +AKK Sbjct: 1 MDAEAEDKTLRTRSKGTEVPMDSLIQEL---------------------SVAYDCSMAKK 39 Query: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120 R +D+ P KRK +K S +D ED ++ ED+G Sbjct: 40 RTAEDQALGVPVNKRKSLLMKPRHYS----PKADCQEDRSDRTEDDG------------- 82 Query: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180 E EE I+ DE + + Sbjct: 83 PLETHGHSTAEEIMIKPMDE-------------------------------------SLL 105 Query: 181 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDK 239 E D Y Y EL+ KSL++LGK ++ + + +E+ +N + SL+ +SD+ Sbjct: 106 STAQENSSRKEDRYSCYQELMVKSLMHLGKFEKNVSVQTVSEN-LNDSGIQSLKAESDE 163 Score = 56.2 bits (134), Expect = 2e-07 Identities = 26/57 (45%), Positives = 34/57 (59%), Gaps = 2/57 (3%) Query: 11 RTRSKGVRVPVEPAIQE--LFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRKTQD 65 R R GV++ +E CP GCDG GH+SGKY HR+ GCPLA KR+ ++ Sbjct: 794 RARKGGVKMTPTKEEKEDPELKCPVIGCDGQGHISGKYTSHRTASGCPLAAKRQKEN 850 Score = 51.6 bits (122), Expect = 4e-06 Identities = 26/55 (47%), Positives = 33/55 (60%), Gaps = 5/55 (9%) Query: 17 VRVPVEPAI--QELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKKRK---TQDK 66 VRVP+E + + CPTPGC G GHV+ HRS+ GCP+A K +QDK Sbjct: 396 VRVPLEILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDK 450 Score = 49.7 bits (117), Expect = 2e-05 Identities = 18/26 (69%), Positives = 21/26 (80%) Query: 31 CPTPGCDGSGHVSGKYARHRSVYGCP 56 CP PGCDG+GHV+G Y HRS+ GCP Sbjct: 368 CPIPGCDGTGHVTGLYPHHRSLSGCP 393 Score = 47.8 bits (112), Expect = 6e-05 Identities = 19/32 (59%), Positives = 23/32 (71%) Query: 26 QELFSCPTPGCDGSGHVSGKYARHRSVYGCPL 57 QEL CP PGC+G GHV+ + HRS+ GCPL Sbjct: 864 QELPHCPLPGCNGLGHVNNVFVTHRSLSGCPL 895 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 84.0 bits (206), Expect = 8e-16 Identities = 55/154 (35%), Positives = 73/154 (47%), Gaps = 22/154 (14%) Query: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVD-------ECDDSDGTEDMDEKEEDEGEEYSED 113 R+ QP++ +++ +A S + D E D KEE EEY D Sbjct: 123 REPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSD 182 Query: 114 N--------DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEE 165 + DE G+ E +EEG E+ EE EE +ED +ED E ED EEEEEEEEEEEEE Sbjct: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242 Query: 166 EENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 EE E+ + QD ++YD E Sbjct: 243 EEEEEEEYE-------QDERDQKEEGNDYDTRSE 269 Score = 64.3 bits (155), Expect = 7e-10 Identities = 34/112 (30%), Positives = 60/112 (53%), Gaps = 8/112 (7%) Query: 60 KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGD 119 +R ++ Q + + + ++ S D+ + +E+ +E E E+ +E + Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220 Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDH 171 EDEE +E EEEEE EEE+E+ E+EEEEE E++E +++EE D+ Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEE--------EEEEEEEYEQDERDQKEEGNDY 264 Score = 60.8 bits (146), Expect = 7e-09 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 2/114 (1%) Query: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSED--NDEPGDEDEEDEEGDREEEEEIEEED 139 + SS ++ ++++ E+ E++ +E EE ED DE DED E+EE + EEEEE EEE+ Sbjct: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246 Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193 E++ E E + EE + + E + +E + R T+ D E Sbjct: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300 Score = 44.7 bits (104), Expect = 5e-04 Identities = 20/70 (28%), Positives = 37/70 (52%) Query: 80 VKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED 139 V+ D ++ ++ + ++ E+EE+E EE E+ +E +E E+DE +EE + + Sbjct: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268 Query: 140 EDDDEDGEDV 149 E D E V Sbjct: 269 EASDSGSESV 278 Score = 34.7 bits (78), Expect = 0.55 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Query: 83 DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142 + VDE D + E+ +E+EE+E EE E + D+ EE + D E + Sbjct: 221 EDEEVDE-DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVS 279 Query: 143 DEDGEDVEDEEEEEEEEEEEEEE 165 DG + +E+++E + Sbjct: 280 FTDGSVRSGSGTDGSDEKKKERK 302 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 84.0 bits (206), Expect = 8e-16 Identities = 55/154 (35%), Positives = 73/154 (47%), Gaps = 22/154 (14%) Query: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVD-------ECDDSDGTEDMDEKEEDEGEEYSED 113 R+ QP++ +++ +A S + D E D KEE EEY D Sbjct: 123 REPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSD 182 Query: 114 N--------DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEE 165 + DE G+ E +EEG E+ EE EE +ED +ED E ED EEEEEEEEEEEEE Sbjct: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242 Query: 166 EENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 EE E+ + QD ++YD E Sbjct: 243 EEEEEEEYE-------QDERDQKEEGNDYDTRSE 269 Score = 64.3 bits (155), Expect = 7e-10 Identities = 34/112 (30%), Positives = 60/112 (53%), Gaps = 8/112 (7%) Query: 60 KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGD 119 +R ++ Q + + + ++ S D+ + +E+ +E E E+ +E + Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220 Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDH 171 EDEE +E EEEEE EEE+E+ E+EEEEE E++E +++EE D+ Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEE--------EEEEEEEYEQDERDQKEEGNDY 264 Score = 60.8 bits (146), Expect = 7e-09 Identities = 36/114 (31%), Positives = 59/114 (51%), Gaps = 2/114 (1%) Query: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSED--NDEPGDEDEEDEEGDREEEEEIEEED 139 + SS ++ ++++ E+ E++ +E EE ED DE DED E+EE + EEEEE EEE+ Sbjct: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246 Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193 E++ E E + EE + + E + +E + R T+ D E Sbjct: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKE 300 Score = 44.7 bits (104), Expect = 5e-04 Identities = 20/70 (28%), Positives = 37/70 (52%) Query: 80 VKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED 139 V+ D ++ ++ + ++ E+EE+E EE E+ +E +E E+DE +EE + + Sbjct: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268 Query: 140 EDDDEDGEDV 149 E D E V Sbjct: 269 EASDSGSESV 278 Score = 34.7 bits (78), Expect = 0.55 Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%) Query: 83 DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142 + VDE D + E+ +E+EE+E EE E + D+ EE + D E + Sbjct: 221 EDEEVDE-DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVS 279 Query: 143 DEDGEDVEDEEEEEEEEEEEEEE 165 DG + +E+++E + Sbjct: 280 FTDGSVRSGSGTDGSDEKKKERK 302 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 82.4 bits (202), Expect = 2e-15 Identities = 61/195 (31%), Positives = 81/195 (41%), Gaps = 56/195 (28%) Query: 15 KGVRVPVEPAIQELFSCPTPGCDGSGH------VSGKYARHRSVYGCPLAKKRKTQDKQP 68 K P + + + TPG G+ GK G K K +D Sbjct: 88 KAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDE 147 Query: 69 QEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-------------EDEGEEYSEDND 115 +E D S DE DD D ED DE E EDE +E ED++ Sbjct: 148 EED-----------DDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDE 196 Query: 116 EPGDEDEEDEEG--------------------------DREEEEEIEEEDEDDDEDGEDV 149 + D++E+D E D +EEE+ E+ED+DDDED ED Sbjct: 197 DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256 Query: 150 EDEEEEEEEEEEEEE 164 +DE++EEEEEEEEEE Sbjct: 257 DDEDDEEEEEEEEEE 271 Score = 71.2 bits (173), Expect = 5e-12 Identities = 45/136 (33%), Positives = 69/136 (50%), Gaps = 43/136 (31%) Query: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEE-----------GDREEEEEIEEEDEDDDED 145 ED DE+E+D+ EE ED DE DEDE++ E +E++E +E+DEDDD+D Sbjct: 143 EDSDEEEDDDSEEDEED-DEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201 Query: 146 GEDVEDEEE----------------------EEEEEEEEEEEEENEDHQMNCHNTRIMQD 183 ED +EE E+E+EEE++E+E++D +D Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDD---------ED 252 Query: 184 TEKDDNNNDEYDNYDE 199 E DD+ +DE + +E Sbjct: 253 DEDDDDEDDEEEEEEE 268 Score = 53.1 bits (126), Expect = 2e-06 Identities = 26/114 (22%), Positives = 60/114 (52%), Gaps = 34/114 (29%) Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGED-----------------VEDEEEEEEEEEEE 162 ++ + E+ D EE+++ EE++EDD+++ ED EDE++E++E++E+ Sbjct: 138 KNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED 197 Query: 163 EEEEENEDHQMNCHNT-----------------RIMQDTEKDDNNNDEYDNYDE 199 ++++E +D + T + +D ++++++ DE D+ DE Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE 251 Score = 48.9 bits (115), Expect = 3e-05 Identities = 30/111 (27%), Positives = 58/111 (52%), Gaps = 9/111 (8%) Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTE--------KDDNNN 191 ED DE+ ED + EE+EE++E+E+E+E+E E M + E +DD+++ Sbjct: 143 EDSDEE-EDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDD 201 Query: 192 DEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNEN 242 +E D+ +E + + K A+ +A+ +E + ++D D +E+ Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDED 252 Score = 40.4 bits (93), Expect = 0.010 Identities = 20/69 (28%), Positives = 40/69 (57%), Gaps = 1/69 (1%) Query: 65 DKQPQEPAP-KRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEE 123 +++ E P K K A + + +D D ED +++++D+ E+ +D+DE +E+EE Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEE 266 Query: 124 DEEGDREEE 132 +EE + +E Sbjct: 267 EEEEEPVKE 275 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 81.3 bits (199), Expect = 5e-15 Identities = 43/79 (54%), Positives = 57/79 (72%) Query: 92 DSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVED 151 +S E+ +E+EE+E EE E+ +E +E+EEDEE EEEEE EEE E++ E+ E + Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943 Query: 152 EEEEEEEEEEEEEEEENED 170 EEEEEE+EEEEEE EE ED Sbjct: 944 EEEEEEDEEEEEELEEVED 962 Score = 75.5 bits (184), Expect = 3e-13 Identities = 36/81 (44%), Positives = 58/81 (71%) Query: 86 SVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDED 145 +++ D+ + E+ +E+EE+E EE ED +E +++EE E + EEEEE EEE E+++ + Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941 Query: 146 GEDVEDEEEEEEEEEEEEEEE 166 E+ E+EE+EEEEEE EE E+ Sbjct: 942 LEEEEEEEDEEEEEELEEVED 962 Score = 72.0 bits (175), Expect = 3e-12 Identities = 35/68 (51%), Positives = 50/68 (73%) Query: 105 DEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEE 164 DE EE E+ +E +E+EE+EE EEEE+ EE E+++E+ E+ E+E EEEE E EEEE Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946 Query: 165 EEENEDHQ 172 EEE+E+ + Sbjct: 947 EEEDEEEE 954 Score = 71.2 bits (173), Expect = 5e-12 Identities = 42/133 (31%), Positives = 67/133 (50%), Gaps = 12/133 (9%) Query: 68 PQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG 127 P P P P + + G ++E S++ +E +E+EE+EE Sbjct: 843 PPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEE 902 Query: 128 DREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKD 187 + EEEE+ EEE+ED++E E+ E+EEEE EEE EEEE E E+ + E+D Sbjct: 903 EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE------------EED 950 Query: 188 DNNNDEYDNYDEL 200 + +E + ++L Sbjct: 951 EEEEEELEEVEDL 963 Score = 67.0 bits (162), Expect = 1e-10 Identities = 32/81 (39%), Positives = 57/81 (70%) Query: 84 SSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD 143 +SS +E ++ + E+ +E+EE+E E++ E+ ++ + EE+EE + E EEE EEE+ + + Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943 Query: 144 EDGEDVEDEEEEEEEEEEEEE 164 E+ E+ ++EEEEE EE E+ E Sbjct: 944 EEEEEEDEEEEEELEEVEDLE 964 Score = 63.2 bits (152), Expect = 1e-09 Identities = 33/76 (43%), Positives = 50/76 (65%) Query: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGE 147 +E ++ + ED +E+EEDE E + E+ +E + +EE EE + E EEE EEEDE+++E+ E Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958 Query: 148 DVEDEEEEEEEEEEEE 163 +VED E E EE Sbjct: 959 EVEDLEFGTAGGEVEE 974 Score = 52.0 bits (123), Expect = 3e-06 Identities = 30/90 (33%), Positives = 51/90 (56%), Gaps = 1/90 (1%) Query: 63 TQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDE 122 + D++ +E + + + + E ++ D E +E+EE+E E E +E G+ +E Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEE 944 Query: 123 EDEEGDREEEEEIEE-EDEDDDEDGEDVED 151 E+EE D EEEEE+EE ED + G +VE+ Sbjct: 945 EEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974 Score = 38.9 bits (89), Expect = 0.029 Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 17/117 (14%) Query: 144 EDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203 E+ V + +EEEEEEEEEEE E+ + +D E+++ + +EY +E Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEE-----EEEEEDFEEEEEDEEEYFEEEE---- 925 Query: 204 SLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRE 260 E+ + E E E+D ++ E L +L V E Sbjct: 926 --------EEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEE 974 >gi|4503257 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 79.0 bits (193), Expect = 3e-14 Identities = 76/295 (25%), Positives = 131/295 (44%), Gaps = 34/295 (11%) Query: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116 ++K QDK + KR+ + +S D + + D E + Sbjct: 376 ISKYAMLQDKSEEGERKKRR---ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASR 432 Query: 117 PGDEDEEDEEGDREEEEEIEEEDED--DDEDGEDVEDEEEEEEEEEEEEEEEE------- 167 +DE+DEE D EEEEE EEE+E+ D E+ ED+E +E +E++EEE+EEEE Sbjct: 433 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG 492 Query: 168 --NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM 225 + + N + ++ ++ ++ E N +V+ SLL+ +A + ES Sbjct: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS---IDAESNG 549 Query: 226 NSNTSNSLEDDSDKNENLGRKSE-LSLDLDSDVVRETVDSLK--------LLAQGHGVVL 276 +LE++S ++ + E L LD S V + S K +L G G+V Sbjct: 550 EQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVS 609 Query: 277 SENMN----DRNYADSMSQ-QDSRNMNYVMLGKPMNNGLMEK---MVEESDEEVC 323 S + N N+ DS + SR P+ N +E+ + E++ +++C Sbjct: 610 STSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKIC 664 >gi|215422388 death-domain associated protein isoform a [Homo sapiens] Length = 740 Score = 79.0 bits (193), Expect = 3e-14 Identities = 76/295 (25%), Positives = 131/295 (44%), Gaps = 34/295 (11%) Query: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116 ++K QDK + KR+ + +S D + + D E + Sbjct: 376 ISKYAMLQDKSEEGERKKRR---ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASR 432 Query: 117 PGDEDEEDEEGDREEEEEIEEEDED--DDEDGEDVEDEEEEEEEEEEEEEEEE------- 167 +DE+DEE D EEEEE EEE+E+ D E+ ED+E +E +E++EEE+EEEE Sbjct: 433 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG 492 Query: 168 --NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM 225 + + N + ++ ++ ++ E N +V+ SLL+ +A + ES Sbjct: 493 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS---IDAESNG 549 Query: 226 NSNTSNSLEDDSDKNENLGRKSE-LSLDLDSDVVRETVDSLK--------LLAQGHGVVL 276 +LE++S ++ + E L LD S V + S K +L G G+V Sbjct: 550 EQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVS 609 Query: 277 SENMN----DRNYADSMSQ-QDSRNMNYVMLGKPMNNGLMEK---MVEESDEEVC 323 S + N N+ DS + SR P+ N +E+ + E++ +++C Sbjct: 610 STSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKIC 664 >gi|215422366 death-domain associated protein isoform b [Homo sapiens] Length = 752 Score = 79.0 bits (193), Expect = 3e-14 Identities = 76/295 (25%), Positives = 131/295 (44%), Gaps = 34/295 (11%) Query: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116 ++K QDK + KR+ + +S D + + D E + Sbjct: 388 ISKYAMLQDKSEEGERKKRR---ARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASR 444 Query: 117 PGDEDEEDEEGDREEEEEIEEEDED--DDEDGEDVEDEEEEEEEEEEEEEEEE------- 167 +DE+DEE D EEEEE EEE+E+ D E+ ED+E +E +E++EEE+EEEE Sbjct: 445 AETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG 504 Query: 168 --NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEM 225 + + N + ++ ++ ++ E N +V+ SLL+ +A + ES Sbjct: 505 DKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSS---IDAESNG 561 Query: 226 NSNTSNSLEDDSDKNENLGRKSE-LSLDLDSDVVRETVDSLK--------LLAQGHGVVL 276 +LE++S ++ + E L LD S V + S K +L G G+V Sbjct: 562 EQPEELTLEEESPVSQLFELEIEALPLDTPSSVETDISSSRKQSEEPFTTVLENGAGMVS 621 Query: 277 SENMN----DRNYADSMSQ-QDSRNMNYVMLGKPMNNGLMEK---MVEESDEEVC 323 S + N N+ DS + SR P+ N +E+ + E++ +++C Sbjct: 622 STSFNGGVSPHNWGDSGPPCKKSRKEKKQTGSGPLGNSYVERQRSVHEKNGKKIC 676 >gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 251 Score = 77.0 bits (188), Expect = 1e-13 Identities = 42/107 (39%), Positives = 67/107 (62%), Gaps = 11/107 (10%) Query: 89 ECDDSDGTED-MDEKEEDE-GEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146 E DSD D +DE+EEDE GE+ +++DE G+E+E DEE D +E+ E +E+D++ E+ Sbjct: 154 EAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEE 213 Query: 147 EDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193 E+ +EE+E+E+E+EEEEE + + + E DD D+ Sbjct: 214 EEFGLDEEDEDEDEDEEEEEGGKGEK---------RKRETDDEGEDD 251 Score = 69.3 bits (168), Expect = 2e-11 Identities = 41/105 (39%), Positives = 61/105 (58%), Gaps = 3/105 (2%) Query: 65 DKQPQEPAPKRKPFAVKADSSSVDE-CDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEE 123 D++ QE AP D DE +D + +D D +EE+ EE ED D GDED+ Sbjct: 149 DREDQE-APDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDD- 206 Query: 124 DEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168 DE + EEE ++EEDED+DED E+ E + E+ + E ++E E++ Sbjct: 207 DEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD 251 Score = 68.9 bits (167), Expect = 3e-11 Identities = 36/92 (39%), Positives = 59/92 (64%), Gaps = 4/92 (4%) Query: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGD---REEEEEIEEE 138 A+ VDE ++ + ED +++++++GEE D ++ DED E +E D EEEEE + Sbjct: 160 AEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLD 219 Query: 139 DEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170 +ED+DED ED E+EE + E+ + E ++E ED Sbjct: 220 EEDEDED-EDEEEEEGGKGEKRKRETDDEGED 250 Score = 58.5 bits (140), Expect = 4e-08 Identities = 31/84 (36%), Positives = 50/84 (59%), Gaps = 7/84 (8%) Query: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEE--EEENE 169 ED + P + E D + EE+EE E+E+++DDEDGE EEE +EE++E+E E + + Sbjct: 151 EDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGE-----EEEFDEEDDEDEDVEGDED 205 Query: 170 DHQMNCHNTRIMQDTEKDDNNNDE 193 D +++ D E +D + DE Sbjct: 206 DDEVSEEEEEFGLDEEDEDEDEDE 229 Score = 58.2 bits (139), Expect = 5e-08 Identities = 29/83 (34%), Positives = 55/83 (66%), Gaps = 4/83 (4%) Query: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE-EEEEEENEDHQMNCHNTR 179 D ED+E + E ++E++DE+GED EDE++E+ EEEE +EE++E+ED + + + Sbjct: 149 DREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDE 208 Query: 180 IMQDTEK---DDNNNDEYDNYDE 199 + ++ E+ D+ + DE ++ +E Sbjct: 209 VSEEEEEFGLDEEDEDEDEDEEE 231 Score = 39.3 bits (90), Expect = 0.022 Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 18/115 (15%) Query: 142 DDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELV 201 +D++ D + E + +EEEE+EE E+ ED D + ++ DE D+ DE V Sbjct: 151 EDQEAPDSDAEVDGVDEEEEDEEGEDEEDE----------DDEDGEEEEFDEEDDEDEDV 200 Query: 202 AKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSD 256 ED + E E + + ED+ ++ E G+ + + D + Sbjct: 201 EGD--------EDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDE 247 Score = 36.6 bits (83), Expect = 0.15 Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 1/105 (0%) Query: 139 DEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNND-EYDNY 197 D D ED E + + E + +EEEE+EE ++ + + + E+DD + D E D Sbjct: 146 DGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDED 205 Query: 198 DELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNEN 242 D+ V++ G ED E E + D+ E+ Sbjct: 206 DDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGED 250 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 75.1 bits (183), Expect = 4e-13 Identities = 40/108 (37%), Positives = 64/108 (59%), Gaps = 3/108 (2%) Query: 50 RSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE 109 R+ Y ++ KRK+ K + P PK +++ S S E DD + +D DE EE+E +E Sbjct: 605 RAAYKEYISNKRKSMTKL-RGPNPKSSRTTLQSKSES--EEDDEEDEDDEDEDEEEEDDE 661 Query: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157 + +++ GD E E + E+ +E EE+DED+D+D +D EDE+ E E Sbjct: 662 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709 Score = 68.9 bits (167), Expect = 3e-11 Identities = 30/94 (31%), Positives = 60/94 (63%), Gaps = 3/94 (3%) Query: 99 MDEKEEDEGEEYSEDNDEPGDEDEEDEE-GDREEE--EEIEEEDEDDDEDGEDVEDEEEE 155 + K E E ++ +++DE DE+EED+E GD E+ + E ED+ EDG++ E+++E+ Sbjct: 634 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693 Query: 156 EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189 E+++E+++E+E+NE + ++ ++ D N Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727 Score = 58.9 bits (141), Expect = 3e-08 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 38/125 (30%) Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVED--EEEEEEEEEEEEEEEENEDHQMNCHN 177 E EED+E D ++E+E +E+E+DDE+G+ ED + E E+E E+ +ENE+ Sbjct: 639 ESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE------- 689 Query: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237 D ++DD+ +D+ D ED ESE +S++S+S D S Sbjct: 690 ----DDEDEDDDEDDDED-----------------ED------NESEGSSSSSSSSGDSS 722 Query: 238 DKNEN 242 D + N Sbjct: 723 DSDSN 727 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 75.1 bits (183), Expect = 4e-13 Identities = 40/108 (37%), Positives = 64/108 (59%), Gaps = 3/108 (2%) Query: 50 RSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE 109 R+ Y ++ KRK+ K + P PK +++ S S E DD + +D DE EE+E +E Sbjct: 605 RAAYKEYISNKRKSMTKL-RGPNPKSSRTTLQSKSES--EEDDEEDEDDEDEDEEEEDDE 661 Query: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157 + +++ GD E E + E+ +E EE+DED+D+D +D EDE+ E E Sbjct: 662 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 709 Score = 68.9 bits (167), Expect = 3e-11 Identities = 30/94 (31%), Positives = 60/94 (63%), Gaps = 3/94 (3%) Query: 99 MDEKEEDEGEEYSEDNDEPGDEDEEDEE-GDREEE--EEIEEEDEDDDEDGEDVEDEEEE 155 + K E E ++ +++DE DE+EED+E GD E+ + E ED+ EDG++ E+++E+ Sbjct: 634 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693 Query: 156 EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189 E+++E+++E+E+NE + ++ ++ D N Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727 Score = 58.9 bits (141), Expect = 3e-08 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 38/125 (30%) Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVED--EEEEEEEEEEEEEEEENEDHQMNCHN 177 E EED+E D ++E+E +E+E+DDE+G+ ED + E E+E E+ +ENE+ Sbjct: 639 ESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE------- 689 Query: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237 D ++DD+ +D+ D ED ESE +S++S+S D S Sbjct: 690 ----DDEDEDDDEDDDED-----------------ED------NESEGSSSSSSSSGDSS 722 Query: 238 DKNEN 242 D + N Sbjct: 723 DSDSN 727 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 75.1 bits (183), Expect = 4e-13 Identities = 40/108 (37%), Positives = 64/108 (59%), Gaps = 3/108 (2%) Query: 50 RSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEE 109 R+ Y ++ KRK+ K + P PK +++ S S E DD + +D DE EE+E +E Sbjct: 642 RAAYKEYISNKRKSMTKL-RGPNPKSSRTTLQSKSES--EEDDEEDEDDEDEDEEEEDDE 698 Query: 110 YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157 + +++ GD E E + E+ +E EE+DED+D+D +D EDE+ E E Sbjct: 699 NGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESE 746 Score = 68.9 bits (167), Expect = 3e-11 Identities = 30/94 (31%), Positives = 60/94 (63%), Gaps = 3/94 (3%) Query: 99 MDEKEEDEGEEYSEDNDEPGDEDEEDEE-GDREEE--EEIEEEDEDDDEDGEDVEDEEEE 155 + K E E ++ +++DE DE+EED+E GD E+ + E ED+ EDG++ E+++E+ Sbjct: 671 LQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 730 Query: 156 EEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189 E+++E+++E+E+NE + ++ ++ D N Sbjct: 731 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764 Score = 58.9 bits (141), Expect = 3e-08 Identities = 40/125 (32%), Positives = 64/125 (51%), Gaps = 38/125 (30%) Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVED--EEEEEEEEEEEEEEEENEDHQMNCHN 177 E EED+E D ++E+E +E+E+DDE+G+ ED + E E+E E+ +ENE+ Sbjct: 676 ESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE------- 726 Query: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237 D ++DD+ +D+ D ED ESE +S++S+S D S Sbjct: 727 ----DDEDEDDDEDDDED-----------------ED------NESEGSSSSSSSSGDSS 759 Query: 238 DKNEN 242 D + N Sbjct: 760 DSDSN 764 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 73.9 bits (180), Expect = 8e-13 Identities = 43/111 (38%), Positives = 65/111 (58%), Gaps = 7/111 (6%) Query: 97 EDMDEKEEDEGEEYSEDNDEPGDED---EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153 E E+EE EGE E+ +E G+E+ EE+ EG+ EEEEE E E E + E+GE +EE Sbjct: 978 EGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEE 1037 Query: 154 EEEEEEEEEEEEEENEDHQMNCHNTR----IMQDTEKDDNNNDEYDNYDEL 200 E EEE EE E+E E E+++ N Q+T +++N + + Y ++ Sbjct: 1038 EGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKV 1088 Score = 72.4 bits (176), Expect = 2e-12 Identities = 40/86 (46%), Positives = 53/86 (61%), Gaps = 5/86 (5%) Query: 92 DSDGTEDMDEKEEDEGEEYSEDNDEPGDEDE-----EDEEGDREEEEEIEEEDEDDDEDG 146 + +G E E EE+EGE ED + G+E+E E+EEG+ E EEE E E E+ + +G Sbjct: 922 EEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEG 981 Query: 147 EDVEDEEEEEEEEEEEEEEEENEDHQ 172 E+ E E E EEEE EEE EEE E + Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEE 1007 Score = 70.1 bits (170), Expect = 1e-11 Identities = 41/83 (49%), Positives = 54/83 (65%), Gaps = 2/83 (2%) Query: 89 ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDRE-EEEEIEEEDEDDDE-DG 146 E ++ +G E+ E EE+EGE E+ E G+ +EE EEG+ E EEEE E E E++ E +G Sbjct: 836 EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEG 895 Query: 147 EDVEDEEEEEEEEEEEEEEEENE 169 E+ E E E EEE E E EEEE E Sbjct: 896 EEEEGEGEGEEEGEGEGEEEEGE 918 Score = 68.9 bits (167), Expect = 3e-11 Identities = 41/116 (35%), Positives = 64/116 (55%), Gaps = 4/116 (3%) Query: 88 DECDDSDGTEDMD-EKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146 +E + +G E+ + E EE EGE E+ + G+E+E +EEG+ E E E E E E ++E+ Sbjct: 959 EEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEE 1018 Query: 147 EDVEDE---EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 +VE E EE E E EEEE EEE E+ + ++ E+++ +Y E Sbjct: 1019 GEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE 1074 Score = 67.0 bits (162), Expect = 1e-10 Identities = 40/114 (35%), Positives = 63/114 (55%), Gaps = 1/114 (0%) Query: 59 KKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPG 118 ++++ +++ +E A K + + D +E + E+ +E E EG E E E Sbjct: 768 REKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGER- 826 Query: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 +E+EE+ EG+ EE E EEE E ++E+GE +EE EE E EEE EE E E + Sbjct: 827 EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880 Score = 65.9 bits (159), Expect = 2e-10 Identities = 36/91 (39%), Positives = 56/91 (61%), Gaps = 1/91 (1%) Query: 81 KADSSSVDECDDSDGTEDMDEKE-EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEED 139 + + +E ++ +G E+ +E E E E EE + +E G+ + E+EEG+ E EEE E E Sbjct: 853 EGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEG 912 Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170 E+++ +G+ E+ EE E E EEEE E E ED Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGED 943 Score = 65.5 bits (158), Expect = 3e-10 Identities = 37/89 (41%), Positives = 53/89 (59%), Gaps = 4/89 (4%) Query: 88 DECDDSDGTEDMDEKEEDEGEEYSEDND----EPGDEDEEDEEGDREEEEEIEEEDEDDD 143 +E ++ +G E+ E EE+EGE E+ + E G+E E +EEG+ E E EEE E + Sbjct: 828 EEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887 Query: 144 EDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 E+ + E EEEE E E EEE E E E+ + Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916 Score = 64.3 bits (155), Expect = 7e-10 Identities = 41/102 (40%), Positives = 57/102 (55%), Gaps = 20/102 (19%) Query: 89 ECDDSDGTEDMDEKE-EDEGEEYSEDNDEPGDEDEEDEEGDRE------------EEEEI 135 E ++ +G + +E+E E+EGEE E +E E EE+EEG+ E EEEE Sbjct: 980 EGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEG 1039 Query: 136 EEEDEDDDEDGEDVEDEEEEEEEEEEE-------EEEEENED 170 EEE E+ +++GE E+ EEEEEEE EEE E +D Sbjct: 1040 EEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQD 1081 Score = 63.9 bits (154), Expect = 9e-10 Identities = 38/95 (40%), Positives = 53/95 (55%), Gaps = 5/95 (5%) Query: 81 KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEI----- 135 + + +E + G E+ +E E + EE E E G+ + E+EEG+ E EEE Sbjct: 907 EGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEG 966 Query: 136 EEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170 EEE E + E+GE +EEE E E EEEE EEE E+ Sbjct: 967 EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001 Score = 63.5 bits (153), Expect = 1e-09 Identities = 41/127 (32%), Positives = 67/127 (52%), Gaps = 18/127 (14%) Query: 62 KTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDM-----DEKEE---------DEG 107 + + ++ +E ++K + +E D +G E+ +EKEE +EG Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822 Query: 108 EEYSEDNDEPGDEDEEDEEGDRE----EEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEE 163 + E+ +E G+ +EE+ EG+ E EEEE E + E++ E+GE E+ EE E E EEEE Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882 Query: 164 EEEENED 170 E E E+ Sbjct: 883 GEGEGEE 889 Score = 63.5 bits (153), Expect = 1e-09 Identities = 36/84 (42%), Positives = 50/84 (59%), Gaps = 3/84 (3%) Query: 89 ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEI---EEEDEDDDED 145 E ++ G + +E+E + EE E +E G+ +EE+ EG EEE E EEE E+ + + Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877 Query: 146 GEDVEDEEEEEEEEEEEEEEEENE 169 GE+ E E E EEE E E EEEE E Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGE 901 Score = 62.8 bits (151), Expect = 2e-09 Identities = 40/110 (36%), Positives = 61/110 (55%), Gaps = 7/110 (6%) Query: 67 QPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE- 125 + +E K + + + +E + +G + E EE+EGE E+ + G+ +EE E Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG 972 Query: 126 -----EGDREEEE-EIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169 EG+ EEEE E E E+E+ +E+GE+ + EEE E E EEEEE E E Sbjct: 973 EGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022 Score = 62.4 bits (150), Expect = 2e-09 Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 6/96 (6%) Query: 81 KADSSSVDECDDSDGTEDMD-EKEEDEGEEYSEDNDEPGDEDEE-----DEEGDREEEEE 134 + + +E + +G E+ + E EE+EGE E+ E E+EE +EEG+ E E Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932 Query: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170 EEE E + EDGE +EEE E E EEEE E E E+ Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968 Score = 62.4 bits (150), Expect = 2e-09 Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 9/163 (5%) Query: 81 KADSSSVDECDDSDGTEDMD-EKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEE-EIEEE 138 + + +E + +G E+ + E EE+EGE E+ E G+ + E+EEG+ E E+ E E E Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGE 949 Query: 139 DEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYD 198 +E+ + +GE+ E E E EEE E E EE E E + ++ E++ E + Sbjct: 950 EEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009 Query: 199 ELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241 E G+ E+ E E E + + E Sbjct: 1010 E-------GEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045 Score = 61.6 bits (148), Expect = 4e-09 Identities = 38/83 (45%), Positives = 50/83 (60%), Gaps = 2/83 (2%) Query: 88 DECDDSDGTEDMDEKE-EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146 +E + +G E+ E E E+EGE E+ + G +EE EEG+ E EEE E E E +D +G Sbjct: 888 EEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE-EGEGEGEDGEG 946 Query: 147 EDVEDEEEEEEEEEEEEEEEENE 169 E E+E E E EEEE E E E E Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEE 969 Score = 60.5 bits (145), Expect = 9e-09 Identities = 35/114 (30%), Positives = 63/114 (55%), Gaps = 1/114 (0%) Query: 60 KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-EDEGEEYSEDNDEPG 118 K + ++++ + + + + + +E + G E+ +E E E+EGEE + +E Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882 Query: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 E E +EEG+ E EEE E + +++ +GE E+E E + EEE EE E E E+ + Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936 Score = 59.7 bits (143), Expect = 2e-08 Identities = 38/92 (41%), Positives = 56/92 (60%), Gaps = 8/92 (8%) Query: 89 ECDDSDGTEDMDEKEEDEGEEYSEDND--EPGDEDEEDEEGDREEEEEIEE-----EDED 141 E ++ +G + +E+ E EGEE + + E G+ + E+EEG+ + EEE EE E+E+ Sbjct: 877 EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936 Query: 142 DDEDGEDVEDEEEEEE-EEEEEEEEEENEDHQ 172 + +GED E E EEEE E E EEEE E E + Sbjct: 937 GEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968 Score = 58.9 bits (141), Expect = 3e-08 Identities = 36/143 (25%), Positives = 72/143 (50%), Gaps = 2/143 (1%) Query: 59 KKR--KTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116 KKR + Q+++ +E +++ + + + + D +E+EE EGE E E Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE 762 Query: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCH 176 + + E EEG+R++EE +E++ ++E + +EEE E EE+EE E E ++ Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822 Query: 177 NTRIMQDTEKDDNNNDEYDNYDE 199 ++ E+ + +E + +E Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEE 845 Score = 58.5 bits (140), Expect = 4e-08 Identities = 51/178 (28%), Positives = 81/178 (45%), Gaps = 38/178 (21%) Query: 94 DGTEDMDEKEE---DEGEEYSEDNDEPGDEDE----------------EDEEGDREEEEE 134 +G +++ EKEE +GEE + E G + E E+EEGDREEEEE Sbjct: 691 EGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEE 750 Query: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEE----EEENEDHQMNCHNTRIMQDTEKDDNN 190 E E +++ E GE+VE E E+EE E ++EE EE+ E+ + + E+ + Sbjct: 751 KEGEGKEEGE-GEEVEGEREKEEGERKKEERAGKEEKGEE-----EGDQGEGEEEETEGR 804 Query: 191 NDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248 +E + E+ G++ E R E E E + ++ E G + E Sbjct: 805 GEEKEEGGEVEG------GEVEEGKGER---EEEEEEGEGEEEEGEGEEEEGEGEEEE 853 Score = 57.8 bits (138), Expect = 6e-08 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 15/92 (16%) Query: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREE--EEEIEEEDEDDDEDGE- 147 ++ +G E E+E++EGE E+ G E++ +EEGD+ E EEE E E+ +E GE Sbjct: 757 EEGEGEEVEGEREKEEGERKKEER--AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814 Query: 148 ----------DVEDEEEEEEEEEEEEEEEENE 169 + E+EEEE E EEEE E EE E Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846 Score = 52.4 bits (124), Expect = 3e-06 Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 8/127 (6%) Query: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE-----DEDDDED 145 ++ +G + +E+ E EGE E+ + G+E+E +EEG+ E+E EE +E+++E+ Sbjct: 1007 EEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066 Query: 146 G---EDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVA 202 G E E+E E ++ EE ++ + + H T + N E + + + Sbjct: 1067 GKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQS 1126 Query: 203 KSLLNLG 209 K LL G Sbjct: 1127 KRLLKNG 1133 Score = 47.0 bits (110), Expect = 1e-04 Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 14/112 (12%) Query: 91 DDSDGTEDMDEKEEDEGEEYSE--DNDEPGD------EDEEDEEGDREEEEEIEEEDEDD 142 + S G E ++E ++GE+ + + PG+ E EE ++ D EE+E+ E E Sbjct: 661 EGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQ 720 Query: 143 DEDGEDVED--EEE----EEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDD 188 E +++E+ EEE EEEE + EEEEE+ + + + + EK++ Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEE 772 Score = 42.4 bits (98), Expect = 0.003 Identities = 43/189 (22%), Positives = 86/189 (45%), Gaps = 20/189 (10%) Query: 84 SSSVDECDDS-DGTEDMDEKEEDEGEEYSEDND-EPGDEDEEDEEGDR--EEEEEIEEED 139 + SV E +D +G D +E G E+ +D + E G++D+ E +R E E+E+ E++ Sbjct: 641 AKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKE 700 Query: 140 EDDDEDGEDVEDEEEEEEEEEEE----EEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYD 195 E DGE E+E++E E+ E +E E+ H ++ ++++ E + Sbjct: 701 EWKKRDGE------EQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGE 754 Query: 196 NYDELVAKSLLNLGKIAEDAAYRARTE----SEMNSNTSNSLEDDSDKNENLGRKSELSL 251 +E + + G+ ++ R + E E + E + ++ E G + E Sbjct: 755 GKEEGEGEEV--EGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812 Query: 252 DLDSDVVRE 260 +++ V E Sbjct: 813 EVEGGEVEE 821 Score = 39.7 bits (91), Expect = 0.017 Identities = 41/169 (24%), Positives = 62/169 (36%), Gaps = 13/169 (7%) Query: 93 SDGTEDMDEKEEDEGEEYSEDNDEP-GDEDEEDEEGD------REEEEEIEEEDEDDDED 145 SD D E E + + E D P G D EEG ++EE E E+D+ E Sbjct: 627 SDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEM 686 Query: 146 GEDVEDEEEEEEEEE------EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 E E+E E+EE EE+E++E E N + + E++ +E + E Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDRE 746 Query: 200 LVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248 + + E E E +K E G + E Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGE 795 Score = 38.5 bits (88), Expect = 0.038 Identities = 50/245 (20%), Positives = 88/245 (35%), Gaps = 41/245 (16%) Query: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEG--------- 107 L K+ P + K++ +++ E DDSD E+M E +E + Sbjct: 508 LNSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGI 567 Query: 108 ---------EEYSEDNDEPGDEDE--EDEEGDREEEEEIEEEDEDDDEDG---------- 146 E +S++ E +E E ED +G+ EE+E+E +E+ G Sbjct: 568 FMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILS 627 Query: 147 EDVEDEEEEEE-------EEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 +D+ D+ E E E E+ E + + QD E++ D+ E Sbjct: 628 DDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEME 687 Query: 200 LVAKSLLNLGKIAE----DAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDS 255 + L + E D + + E E + E + E G E D + Sbjct: 688 RPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREE 747 Query: 256 DVVRE 260 + +E Sbjct: 748 EEEKE 752 >gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 1 [Homo sapiens] Length = 268 Score = 73.2 bits (178), Expect = 1e-12 Identities = 44/125 (35%), Positives = 64/125 (51%), Gaps = 27/125 (21%) Query: 94 DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG------DREEEEEIEEEDEDDDED-- 145 DG + D + D EE ED DE +E+EE+E G + EEEEE E+EDED+DED Sbjct: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205 Query: 146 -----------------GEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDD 188 E+++DEE++++ EE EEEEE E+ + + +D E D Sbjct: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK--RDAEDDG 263 Query: 189 NNNDE 193 D+ Sbjct: 264 EEEDD 268 Score = 64.7 bits (156), Expect = 5e-10 Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%) Query: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169 EDN+ P E+E+DE+GD ++EEE E E + E+ E+ E+EE+E+E+E+E+E E Sbjct: 151 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 210 Query: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194 + + + +M++ +D+ ++D+Y Sbjct: 211 EGEEEVGLSYLMKEEIQDEEDDDDY 235 Score = 48.1 bits (113), Expect = 5e-05 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 29/93 (31%) Query: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE-------------------DEED---- 124 +E +G E+ +E+EE+E E+ ED DE G E DEED Sbjct: 176 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 235 Query: 125 -EEGDREEEEEI-----EEEDEDDDEDGEDVED 151 EEG+ EEEEE E+ D ++DGE+ +D Sbjct: 236 VEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268 Score = 43.9 bits (102), Expect = 0.001 Identities = 25/99 (25%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Query: 145 DGEDVEDEE--EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVA 202 DG D ED E + EEE++E+ +E++ E+ + ++ E+++ DE ++ DE A Sbjct: 146 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205 Query: 203 KSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241 S L G+ +Y + E + + + +E+ ++ E Sbjct: 206 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 244 Score = 38.9 bits (89), Expect = 0.029 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%) Query: 64 QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105 +D + +E P + + +E +D D ED DE KEE Sbjct: 168 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 226 Query: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145 + EE +D E G+E+EE+ E G R E+ + + ED+ ++ED Sbjct: 227 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 267 >gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 2 [Homo sapiens] Length = 227 Score = 73.2 bits (178), Expect = 1e-12 Identities = 44/125 (35%), Positives = 64/125 (51%), Gaps = 27/125 (21%) Query: 94 DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG------DREEEEEIEEEDEDDDED-- 145 DG + D + D EE ED DE +E+EE+E G + EEEEE E+EDED+DED Sbjct: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164 Query: 146 -----------------GEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDD 188 E+++DEE++++ EE EEEEE E+ + + +D E D Sbjct: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK--RDAEDDG 222 Query: 189 NNNDE 193 D+ Sbjct: 223 EEEDD 227 Score = 64.7 bits (156), Expect = 5e-10 Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%) Query: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169 EDN+ P E+E+DE+GD ++EEE E E + E+ E+ E+EE+E+E+E+E+E E Sbjct: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 169 Query: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194 + + + +M++ +D+ ++D+Y Sbjct: 170 EGEEEVGLSYLMKEEIQDEEDDDDY 194 Score = 48.1 bits (113), Expect = 5e-05 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 29/93 (31%) Query: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE-------------------DEED---- 124 +E +G E+ +E+EE+E E+ ED DE G E DEED Sbjct: 135 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 194 Query: 125 -EEGDREEEEEI-----EEEDEDDDEDGEDVED 151 EEG+ EEEEE E+ D ++DGE+ +D Sbjct: 195 VEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227 Score = 43.9 bits (102), Expect = 0.001 Identities = 25/99 (25%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Query: 145 DGEDVEDEE--EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVA 202 DG D ED E + EEE++E+ +E++ E+ + ++ E+++ DE ++ DE A Sbjct: 105 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164 Query: 203 KSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241 S L G+ +Y + E + + + +E+ ++ E Sbjct: 165 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 203 Score = 38.9 bits (89), Expect = 0.029 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%) Query: 64 QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105 +D + +E P + + +E +D D ED DE KEE Sbjct: 127 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 185 Query: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145 + EE +D E G+E+EE+ E G R E+ + + ED+ ++ED Sbjct: 186 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 226 >gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 3 [Homo sapiens] Length = 220 Score = 73.2 bits (178), Expect = 1e-12 Identities = 44/125 (35%), Positives = 64/125 (51%), Gaps = 27/125 (21%) Query: 94 DGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG------DREEEEEIEEEDEDDDED-- 145 DG + D + D EE ED DE +E+EE+E G + EEEEE E+EDED+DED Sbjct: 98 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 157 Query: 146 -----------------GEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDD 188 E+++DEE++++ EE EEEEE E+ + + +D E D Sbjct: 158 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK--RDAEDDG 215 Query: 189 NNNDE 193 D+ Sbjct: 216 EEEDD 220 Score = 64.7 bits (156), Expect = 5e-10 Identities = 30/85 (35%), Positives = 56/85 (65%), Gaps = 2/85 (2%) Query: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD--EDGEDVEDEEEEEEEEEEEEEEEENE 169 EDN+ P E+E+DE+GD ++EEE E E + E+ E+ E+EE+E+E+E+E+E E Sbjct: 103 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELG 162 Query: 170 DHQMNCHNTRIMQDTEKDDNNNDEY 194 + + + +M++ +D+ ++D+Y Sbjct: 163 EGEEEVGLSYLMKEEIQDEEDDDDY 187 Score = 48.1 bits (113), Expect = 5e-05 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 29/93 (31%) Query: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE-------------------DEED---- 124 +E +G E+ +E+EE+E E+ ED DE G E DEED Sbjct: 128 NEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDY 187 Query: 125 -EEGDREEEEEI-----EEEDEDDDEDGEDVED 151 EEG+ EEEEE E+ D ++DGE+ +D Sbjct: 188 VEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220 Score = 43.9 bits (102), Expect = 0.001 Identities = 25/99 (25%), Positives = 51/99 (51%), Gaps = 2/99 (2%) Query: 145 DGEDVEDEE--EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVA 202 DG D ED E + EEE++E+ +E++ E+ + ++ E+++ DE ++ DE A Sbjct: 98 DGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 157 Query: 203 KSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241 S L G+ +Y + E + + + +E+ ++ E Sbjct: 158 GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEE 196 Score = 38.9 bits (89), Expect = 0.029 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 20/101 (19%) Query: 64 QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDE------------------KEED 105 +D + +E P + + +E +D D ED DE KEE Sbjct: 120 EDDEEEEENEAGPPEGYEEEEEEEEE-EDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 178 Query: 106 EGEEYSEDNDEPGDEDEED-EEGDREEEEEIEEEDEDDDED 145 + EE +D E G+E+EE+ E G R E+ + + ED+ ++ED Sbjct: 179 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 219 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 72.8 bits (177), Expect = 2e-12 Identities = 53/165 (32%), Positives = 84/165 (50%), Gaps = 27/165 (16%) Query: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDED-EEDEEGDREEEEEIEEED----EDDDED 145 ++ D ED +++ E++GE ED DE G+ED +ED+ G+ + E+ E+ED ED + Sbjct: 126 EEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGN 185 Query: 146 GEDVEDEEEEEEEEEEEEEE---EENED-----HQMNCHNTRIMQD-TEKDDNNNDEYDN 196 GED +++ E+E+EEE+ +E +ENED + + ++ +D E++D DE N Sbjct: 186 GEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGN 245 Query: 197 YDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241 +E GK ED E E EDD K E Sbjct: 246 EEE--------AGKEKEDL-----KEEEEGKEEDEIKEDDGKKEE 277 Score = 56.2 bits (134), Expect = 2e-07 Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 21/101 (20%) Query: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEED---EEGDREE-------EEEIEEEDE 140 D ED EK EDE EE ED E GD E + E+GD++E E+E E ED Sbjct: 181 DGKGNGEDGKEKGEDEKEE--EDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDG 238 Query: 141 DDDEDG---------EDVEDEEEEEEEEEEEEEEEENEDHQ 172 +DE G ED+++EEE +EE+E +E++ + E+ Q Sbjct: 239 KEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQ 279 Score = 55.5 bits (132), Expect = 3e-07 Identities = 36/177 (20%), Positives = 80/177 (45%), Gaps = 1/177 (0%) Query: 72 APKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREE 131 AP + V+ ++++ + G + E + EE + DE +E+ E G ++ Sbjct: 90 APASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDK 149 Query: 132 EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNN 191 +E+ EE+ ++D E ED +E+E+ ++ E+ + ED + + + +D ++ + Sbjct: 150 DEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK 209 Query: 192 DEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248 + D ++ K ++ K+ ED R + + N + ++ D E K E Sbjct: 210 ENEDGKEKGDKKEGKDV-KVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265 Score = 52.0 bits (123), Expect = 3e-06 Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 4/80 (5%) Query: 88 DECDDSDGTEDMDEKE---EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDE 144 D + DG E+ D KE + EG++ DE ED +++EG EEE E+ED ++E Sbjct: 201 DRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEE 260 Query: 145 DGEDVEDEEEEEEEEEEEEE 164 +G++ EDE +E++ ++EE + Sbjct: 261 EGKE-EDEIKEDDGKKEEPQ 279 Score = 51.2 bits (121), Expect = 6e-06 Identities = 45/185 (24%), Positives = 80/185 (43%), Gaps = 25/185 (13%) Query: 63 TQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDE 122 T + +P+ + RK +K S ++E D+ + K+E EE +N + G+ Sbjct: 31 TPEVKPKRTSSSRK---MKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKI 87 Query: 123 EDEEGDREE-----EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHN 177 + +E EE IE+ E E E V E + EEE+++E+EE++NE Sbjct: 88 TEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNE-------- 139 Query: 178 TRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDS 237 EK + ++ D E K N + EDA + + + + + + ED Sbjct: 140 -------EKGEAGKEDKDEKGEEDGKEDKNGNEKGEDA--KEKEDGKKGEDGKGNGEDGK 190 Query: 238 DKNEN 242 +K E+ Sbjct: 191 EKGED 195 Score = 42.0 bits (97), Expect = 0.003 Identities = 42/196 (21%), Positives = 82/196 (41%), Gaps = 20/196 (10%) Query: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEK--EEDEGEEYSEDND 115 ++K KT+ +E + +V E D ++ ++ + K E E+ + Sbjct: 42 SRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVK 101 Query: 116 EPGDEDEEDEEGDREEE--EEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQM 173 E ED ++ G+++E E++ E+ED ED ED + EE+ E +E+++E + Sbjct: 102 EENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEED----QNEEKGEAGKEDKDEKGE--- 154 Query: 174 NCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGK-IAEDAAYRARTESEMNSNTSNS 232 +D ++D N N++ ++ E GK ED + E E Sbjct: 155 --------EDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETG 206 Query: 233 LEDDSDKNENLGRKSE 248 +++ + G K E Sbjct: 207 DGKENEDGKEKGDKKE 222 Score = 40.8 bits (94), Expect = 0.008 Identities = 30/97 (30%), Positives = 52/97 (53%), Gaps = 11/97 (11%) Query: 60 KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTE---DMDEKEEDEGEEYSEDNDE 116 K K +D++ +E +++ K + ++ D +G + DEKE ++G+E N+E Sbjct: 190 KEKGEDEKEEED--RKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEE 247 Query: 117 P-GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152 G E E D +EEEE +EEDE ++DG+ E + Sbjct: 248 EAGKEKE-----DLKEEEEGKEEDEIKEDDGKKEEPQ 279 >gi|7657138 golgi integral membrane protein 4 [Homo sapiens] Length = 696 Score = 72.4 bits (176), Expect = 2e-12 Identities = 39/131 (29%), Positives = 68/131 (51%), Gaps = 6/131 (4%) Query: 67 QPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEE 126 +P+E P+ +AD ++V++ + +D + E E +E E+ E+N P + +E+ + Sbjct: 525 EPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREEN-LPDENEEQKQS 583 Query: 127 GDREEEEEIEEE-----DEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIM 181 ++E E+EE + D ED D + +EE EEE +E+ EE+ + + N T Sbjct: 584 NQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGE 643 Query: 182 QDTEKDDNNND 192 D DD NND Sbjct: 644 NDENTDDKNND 654 Score = 60.1 bits (144), Expect = 1e-08 Identities = 43/213 (20%), Positives = 91/213 (42%), Gaps = 26/213 (12%) Query: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDE 116 L ++ + ++ +PQ R+ A + + + + G + + E + + E + Sbjct: 460 LQRQAELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGD 519 Query: 117 PGDEDEEDEEGDREEEEEIE----------------EEDEDDDEDGEDVEDEEEEEEEEE 160 PG+ E E+G RE + E E + ED+ E+ E V +E +E EE Sbjct: 520 PGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEE 579 Query: 161 EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRAR 220 +++ ++ E+ ++ H +++DN +++Y E ++ ED + Sbjct: 580 QKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAE---------EEVQEDLTEEKK 630 Query: 221 TESEMNS-NTSNSLEDDSDKNENLGRKSELSLD 252 E E N+ T ++++D N G + E+ D Sbjct: 631 RELEHNAEETYGENDENTDDKNNDGEEQEVRDD 663 Score = 50.8 bits (120), Expect = 7e-06 Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 9/80 (11%) Query: 100 DEKEEDEGEEYSEDNDEPGDED---EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156 D++E++ E+Y E+ +E ED E+ E + EE E DE+ D+ D E++E + Sbjct: 603 DQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRD 662 Query: 157 E------EEEEEEEEEENED 170 + EE EEEEEE ED Sbjct: 663 DNRPKGREEHYEEEEEEEED 682 Score = 49.7 bits (117), Expect = 2e-05 Identities = 38/163 (23%), Positives = 70/163 (42%), Gaps = 7/163 (4%) Query: 9 RHRTRSKGVRV--PVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVY--GCPLAKKRKTQ 64 RH R +G R P A + P D + ++ V P + + Q Sbjct: 523 RHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQKQ 582 Query: 65 DKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEED 124 Q QE + + + + D+ +D+ + +E EE+ E+ +E+ + + E+ Sbjct: 583 SNQKQENTEVEEHLVM---AGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEE 639 Query: 125 EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167 G+ +E + + D ++ E +D + EE EEEEEEEE+ Sbjct: 640 TYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEED 682 Score = 44.3 bits (103), Expect = 7e-04 Identities = 33/186 (17%), Positives = 74/186 (39%), Gaps = 14/186 (7%) Query: 79 AVKADSSSVDECDDSDGTEDMDEKE-------EDEGEEYSEDNDEPGDEDEEDEEGDREE 131 A + D+ DE + G ++ E E + + ++ P D+ E + EE Sbjct: 505 AYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEE 564 Query: 132 EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE-------EEEEENEDHQMNCHNTRIMQDT 184 E++ EE+ D+ + + ++++E E EE +++E+N D Q +Q+ Sbjct: 565 AEQVREENLPDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQED 624 Query: 185 EKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLG 244 ++ + N +E ++ N D + + E++ ++ E+ Sbjct: 625 LTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYEEEEEEEEDGA 684 Query: 245 RKSELS 250 +E S Sbjct: 685 AVAEKS 690 Score = 35.4 bits (80), Expect = 0.32 Identities = 26/113 (23%), Positives = 47/113 (41%), Gaps = 7/113 (6%) Query: 101 EKEEDEGEEYSEDNDE-------PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153 EK E +E S +ND PG ++ +E E + E ++ E E EE Sbjct: 273 EKPTREVQEVSRNNDVWQNHEAVPGRAEDTKLYAPTHKEAEFQAPPEPIQQEVERREPEE 332 Query: 154 EEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLL 206 + EEE + EEE + + D ++ + + + +++ A +LL Sbjct: 333 HQVEEEHRKALEEEEMEQVGQAEHLEEEHDPSPEEQDREWKEQHEQREAANLL 385 Score = 35.0 bits (79), Expect = 0.42 Identities = 49/227 (21%), Positives = 86/227 (37%), Gaps = 39/227 (17%) Query: 123 EDEEGDREEEEEIEEEDEDDDEDGEDVEDEE------EEEEEEEEEEEEEENEDHQMNCH 176 E EEG + +E++ ++ D D + V+ E EE E + + ++E E N H Sbjct: 465 ELEEGRPQHQEQLRQQAHYDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRH 524 Query: 177 NTRIMQDTE-----------------KDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRA 219 R E DD NN D ++E A+ + E+ + Sbjct: 525 EPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEE--AEQVREENLPDENEEQKQ 582 Query: 220 RTESEMNSNTSNSL-----EDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGV 274 + + N+ L D + N + + E ++ D+ E L+ A+ Sbjct: 583 SNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETYG 642 Query: 275 VLSENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEE 321 EN +D+N + +Q+ R+ N +P G E EE +EE Sbjct: 643 ENDENTDDKN--NDGEEQEVRDDN-----RP--KGREEHYEEEEEEE 680 >gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 272 Score = 72.0 bits (175), Expect = 3e-12 Identities = 42/107 (39%), Positives = 60/107 (56%), Gaps = 17/107 (15%) Query: 89 ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGED 148 E DSD D +KEE+ DE G+++++ E D EEEE EEEDED+D +G+D Sbjct: 174 EAPDSDAQVDGVDKEEE---------DEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDD 224 Query: 149 VEDEEEEEEEE--------EEEEEEEENEDHQMNCHNTRIMQDTEKD 187 +DE EEEEE +E+E+E+E E+ N + D E+D Sbjct: 225 DKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271 Score = 68.6 bits (166), Expect = 3e-11 Identities = 39/94 (41%), Positives = 58/94 (61%), Gaps = 6/94 (6%) Query: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE- 140 A VD+ ++ + ED + E ++GEE E+ DE DEDE D EGD +++E EEE+E Sbjct: 180 AQVDGVDKEEEDEEGEDEKDXENEDGEE--EELDEEEDEDE-DVEGDDDKDEVSEEEEEF 236 Query: 141 --DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 D DED ED +++EEEEE + E + E +D + Sbjct: 237 GLDKDEDDEDEDEDEEEEESGKGENRKRETDDEE 270 Score = 62.8 bits (151), Expect = 2e-09 Identities = 37/107 (34%), Positives = 60/107 (56%), Gaps = 3/107 (2%) Query: 63 TQDKQPQEPAPKRKPFAVKADSSSVDE-CDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED 121 T D + QE AP D DE +D E+ D +EE+ EE ED D GD+D Sbjct: 167 TYDPEDQE-APDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDD 225 Query: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168 + DE + EEE ++++++D+DED ++ E+E + E + E ++EE+ Sbjct: 226 K-DEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271 Score = 59.7 bits (143), Expect = 2e-08 Identities = 32/92 (34%), Positives = 56/92 (60%), Gaps = 2/92 (2%) Query: 108 EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167 + Y ++ E D D + + D+EEE+E E EDE D E+ ED E+EE +EEE+E+E+ E + Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDE-EGEDEKDXEN-EDGEEEELDEEEDEDEDVEGD 223 Query: 168 NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 ++ +++ D ++DD + DE + +E Sbjct: 224 DDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEE 255 Score = 52.0 bits (123), Expect = 3e-06 Identities = 24/59 (40%), Positives = 38/59 (64%), Gaps = 1/59 (1%) Query: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146 DE +D +G +D DE E+E EE+ D DE ++++EDEE + + E + + DD+EDG Sbjct: 215 DEDEDVEGDDDKDEVSEEE-EEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272 Score = 36.2 bits (82), Expect = 0.19 Identities = 21/109 (19%), Positives = 51/109 (46%), Gaps = 10/109 (9%) Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 + +D++ D + + + ++EEE+EE E+ +D + + + E +D + + D+ DE Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDE 228 Query: 200 LVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248 + E+ + + + + E++S K EN R+++ Sbjct: 229 V----------SEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETD 267 >gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 272 Score = 72.0 bits (175), Expect = 3e-12 Identities = 42/107 (39%), Positives = 60/107 (56%), Gaps = 17/107 (15%) Query: 89 ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGED 148 E DSD D +KEE+ DE G+++++ E D EEEE EEEDED+D +G+D Sbjct: 174 EAPDSDAQVDGVDKEEE---------DEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDD 224 Query: 149 VEDEEEEEEEE--------EEEEEEEENEDHQMNCHNTRIMQDTEKD 187 +DE EEEEE +E+E+E+E E+ N + D E+D Sbjct: 225 DKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271 Score = 68.6 bits (166), Expect = 3e-11 Identities = 39/94 (41%), Positives = 58/94 (61%), Gaps = 6/94 (6%) Query: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE- 140 A VD+ ++ + ED + E ++GEE E+ DE DEDE D EGD +++E EEE+E Sbjct: 180 AQVDGVDKEEEDEEGEDEKDXENEDGEE--EELDEEEDEDE-DVEGDDDKDEVSEEEEEF 236 Query: 141 --DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 D DED ED +++EEEEE + E + E +D + Sbjct: 237 GLDKDEDDEDEDEDEEEEESGKGENRKRETDDEE 270 Score = 62.8 bits (151), Expect = 2e-09 Identities = 37/107 (34%), Positives = 60/107 (56%), Gaps = 3/107 (2%) Query: 63 TQDKQPQEPAPKRKPFAVKADSSSVDE-CDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED 121 T D + QE AP D DE +D E+ D +EE+ EE ED D GD+D Sbjct: 167 TYDPEDQE-APDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDD 225 Query: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168 + DE + EEE ++++++D+DED ++ E+E + E + E ++EE+ Sbjct: 226 K-DEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEED 271 Score = 59.7 bits (143), Expect = 2e-08 Identities = 32/92 (34%), Positives = 56/92 (60%), Gaps = 2/92 (2%) Query: 108 EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167 + Y ++ E D D + + D+EEE+E E EDE D E+ ED E+EE +EEE+E+E+ E + Sbjct: 166 DTYDPEDQEAPDSDAQVDGVDKEEEDE-EGEDEKDXEN-EDGEEEELDEEEDEDEDVEGD 223 Query: 168 NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 ++ +++ D ++DD + DE + +E Sbjct: 224 DDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEE 255 Score = 52.0 bits (123), Expect = 3e-06 Identities = 24/59 (40%), Positives = 38/59 (64%), Gaps = 1/59 (1%) Query: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146 DE +D +G +D DE E+E EE+ D DE ++++EDEE + + E + + DD+EDG Sbjct: 215 DEDEDVEGDDDKDEVSEEE-EEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDEEDG 272 Score = 36.2 bits (82), Expect = 0.19 Identities = 21/109 (19%), Positives = 51/109 (46%), Gaps = 10/109 (9%) Query: 140 EDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 + +D++ D + + + ++EEE+EE E+ +D + + + E +D + + D+ DE Sbjct: 169 DPEDQEAPDSDAQVDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDEDEDVEGDDDKDE 228 Query: 200 LVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248 + E+ + + + + E++S K EN R+++ Sbjct: 229 V----------SEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETD 267 >gi|4759128 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 [Homo sapiens] Length = 1099 Score = 71.2 bits (173), Expect = 5e-12 Identities = 43/137 (31%), Positives = 72/137 (52%), Gaps = 22/137 (16%) Query: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-EDEGEEYSEDNDE 116 A + +T++K E P+ + +EC+D + E + E EDEGE ++ED + Sbjct: 764 AGEGETEEKSGGETQPEGE--GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEM 821 Query: 117 PGDEDEED-------------------EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157 G+E E + E+G + + EEE+E+++E E+ E+EE+EEE Sbjct: 822 KGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEE 881 Query: 158 EEEEEEEEEENEDHQMN 174 EEEEEEEEE+ + ++ Sbjct: 882 EEEEEEEEEKGNEEPLS 898 Score = 55.8 bits (133), Expect = 2e-07 Identities = 51/208 (24%), Positives = 86/208 (41%), Gaps = 22/208 (10%) Query: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSV-----DECDDSDGTEDMDEKEEDEGEEYSE 112 A+ + + +P+E P + P AV + V D+ ++ G ED+ E E Sbjct: 702 AQPQAKAESKPEEEEPAKLP-AVTVTPAPVPDIKGDQKENPGGQEDVAEAEST------- 753 Query: 113 DNDEPGDEDEEDEEGDREEEEEIEEEDEDDDE-----DGEDVEDEEEEE---EEEEEEEE 164 + PG+E E EG+ EE+ E + E + E GE+ EDE E E + E E+E Sbjct: 754 -GEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEG 812 Query: 165 EEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESE 224 E ED +M + +N+ + ++ + + G E+ E E Sbjct: 813 EIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEE 872 Query: 225 MNSNTSNSLEDDSDKNENLGRKSELSLD 252 E++ ++ E G + LSLD Sbjct: 873 EEEEEQEEEEEEEEEEEEKGNEEPLSLD 900 >gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A [Homo sapiens] Length = 249 Score = 70.5 bits (171), Expect = 9e-12 Identities = 46/95 (48%), Positives = 59/95 (62%), Gaps = 14/95 (14%) Query: 89 ECDDSDG---TEDMDEKEEDEGEE-YSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD- 143 E DSD E +D++EEDE EE Y ED DE++EDEE + EEE+ EE+ED++ Sbjct: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEG 213 Query: 144 -EDGEDVEDEEEEEEEEEEE-------EEEEENED 170 DGE V+DEE+EEE EEE E E+E ED Sbjct: 214 YNDGE-VDDEEDEEELGEEERGQKRKREPEDEGED 247 Score = 63.9 bits (154), Expect = 9e-10 Identities = 38/101 (37%), Positives = 60/101 (59%), Gaps = 9/101 (8%) Query: 98 DMDEKE--EDEGEEYSED-NDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEE 154 D D+KE + + E Y E +DE DEDEE+ + D + E+ E+EDE+++ + EDV EEE Sbjct: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 Query: 155 EEE------EEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189 E+E E ++EE+EEE + + R +D +DD+ Sbjct: 209 EDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 Score = 60.1 bits (144), Expect = 1e-08 Identities = 34/88 (38%), Positives = 54/88 (61%), Gaps = 6/88 (6%) Query: 87 VDECDDSDGTEDMDEKEEDEG---EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE-DD 142 V+ DD + ED +E +ED +E ED +E G +EED G+ EE+EE + E DD Sbjct: 164 VEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEG--EEEDVSGEEEEDEEGYNDGEVDD 221 Query: 143 DEDGEDVEDEEEEEEEEEEEEEEEENED 170 +ED E++ +EE ++ + E E+E E++D Sbjct: 222 EEDEEELGEEERGQKRKREPEDEGEDDD 249 Score = 58.9 bits (141), Expect = 3e-08 Identities = 37/86 (43%), Positives = 47/86 (54%), Gaps = 9/86 (10%) Query: 110 YSEDNDEPGDEDEED--EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167 Y D+ E D D E E D EEE+E EEE ++D + ED EDE+EEEE EEE+ EE Sbjct: 148 YDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEE 207 Query: 168 NEDHQMNCHNTRIMQDTEKDDNNNDE 193 ED + D E DD ++E Sbjct: 208 EEDEEG-------YNDGEVDDEEDEE 226 Score = 43.1 bits (100), Expect = 0.002 Identities = 21/80 (26%), Positives = 43/80 (53%) Query: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180 D +D+E + E E +D++ED ++ E +E+ + E+EE+E+EE E + + Sbjct: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 Query: 181 MQDTEKDDNNNDEYDNYDEL 200 + +D D+ ++ +EL Sbjct: 209 EDEEGYNDGEVDDEEDEEEL 228 Score = 43.1 bits (100), Expect = 0.002 Identities = 19/66 (28%), Positives = 39/66 (59%) Query: 83 DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142 D+ V++ +D D E+ +E++ EE E+ G+ D+E++E + EEE ++ + Sbjct: 182 DAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREP 241 Query: 143 DEDGED 148 +++GED Sbjct: 242 EDEGED 247 Score = 40.0 bits (92), Expect = 0.013 Identities = 20/79 (25%), Positives = 46/79 (58%), Gaps = 5/79 (6%) Query: 126 EGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE-----EEEEEENEDHQMNCHNTRI 180 +G +++E + D + +G D E+E+E+EEE +E E+EE+E+E+ + + Sbjct: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205 Query: 181 MQDTEKDDNNNDEYDNYDE 199 ++ +++ N+ E D+ ++ Sbjct: 206 EEEEDEEGYNDGEVDDEED 224 Score = 33.9 bits (76), Expect = 0.94 Identities = 20/104 (19%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 145 DGEDVEDEEEEEEEEE-------EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNY 197 DG D +D+E + + E +EEE+E+ E++ + +D ++++ +E + Sbjct: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205 Query: 198 DELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241 +E + N G++ ++ E E ED+ + ++ Sbjct: 206 EEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 >gi|21735569 claspin [Homo sapiens] Length = 1339 Score = 69.7 bits (169), Expect = 2e-11 Identities = 35/104 (33%), Positives = 64/104 (61%) Query: 66 KQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDE 125 K + A K + F + ++ + D+ DG E+ +E+EE+ +E ED +E +++E++E Sbjct: 598 KAKLQEAMKLRRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEE 657 Query: 126 EGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENE 169 E + EEE+E EEE+E + E E + EE E ++E+E ++E N+ Sbjct: 658 ELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKENND 701 Score = 62.8 bits (151), Expect = 2e-09 Identities = 46/151 (30%), Positives = 72/151 (47%), Gaps = 9/151 (5%) Query: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ------M 173 ++E+ E + EEEEE+ +E E+D E+ + E++EEE EEEEE+EEEEE E +Q + Sbjct: 623 DNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLL 682 Query: 174 NCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSL 233 + + E D NND + V L++ K + + + Sbjct: 683 SSEEIETKDEKEMDKENNDGSSEIGKAV--GFLSVPKSLSSDSTLLLFKDSSSKMGYFPT 740 Query: 234 EDDSDKNENLGRKSELSLDLDSDVVRETVDS 264 E+ S+ +EN G K LD D T +S Sbjct: 741 EEKSETDENSG-KQPSKLDEDDSCSLLTKES 770 Score = 45.8 bits (107), Expect = 2e-04 Identities = 52/232 (22%), Positives = 93/232 (40%), Gaps = 33/232 (14%) Query: 43 SGKYARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEK 102 SGK+ + P + + Q+K+ P + A+ + S D+ ++ + E D + Sbjct: 945 SGKFTSQDA--STPASSELNKQEKESSMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFR 1002 Query: 103 EEDEGEEYSEDNDEPGDEDE----EDEEGDREEE-----EEIEEE-------DEDDDEDG 146 E+ D DE D ED E D EEE E+++ + +++ + G Sbjct: 1003 LVSNDNEFDSDEDEHSDSGNDLALEDHEDDDEEELLKRSEKLKRQMRLRKYLEDEAEVSG 1062 Query: 147 EDVEDEEEEEEEEEEEEEEEENE-----DHQMNCHNTRIMQDTEKDDNNNDEYDNYDELV 201 DV E+E + EE +E EE+ + D ++ +I T DD+ L Sbjct: 1063 SDVGSEDEYDGEEIDEYEEDVIDEVLPSDEELQSQIKKIHMKTMLDDDKRQL-----RLY 1117 Query: 202 AKSLLNLGKIAEDAAYRARTESEMNSNTSNSL-----EDDSDKNENLGRKSE 248 + L G + D R R N + ++ + + D D+ E +SE Sbjct: 1118 QERYLADGDLHSDGPGRMRKFRWKNIDDASQMDLFHRDSDDDQTEEQLDESE 1169 Score = 32.7 bits (73), Expect = 2.1 Identities = 31/147 (21%), Positives = 57/147 (38%), Gaps = 17/147 (11%) Query: 112 EDNDEPGDEDEED-------EEGDREEEEEIEEED------EDDDEDGEDVEDEEEEEEE 158 E+ D P D + EGD +EE + ++ +D D + ED E+ Sbjct: 22 EEADSPSDSGQGSYETIGPLSEGDSDEEIFVSKKLKNRKVLQDSDSETEDTNASPEKTTY 81 Query: 159 EEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYR 218 + EEE +EN N RI + D + E Y E + + K + + + Sbjct: 82 DSAEEENKENLYAGKNTKIKRIYKTVADSDESYMEKSLYQENLEAQV----KPCLELSLQ 137 Query: 219 ARTESEMNSNTSNSLEDDSDKNENLGR 245 + ++ ++ +S + DK G+ Sbjct: 138 SGNSTDFTTDRKSSKKHIHDKEGTAGK 164 Score = 31.6 bits (70), Expect = 4.7 Identities = 39/167 (23%), Positives = 66/167 (39%), Gaps = 19/167 (11%) Query: 93 SDGTEDMDEKEE-DEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVED 151 SD E+M+E G+ S+D P + ++E E D E+ + Sbjct: 931 SDKKENMEELLNLCSGKFTSQDASTPASSELN--------KQEKESSMGDPMEEALALCS 982 Query: 152 EEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNND------EYDNYDELVAKSL 205 ++EEE+EEEE + ++ N + E D+ ND E D+ +EL+ +S Sbjct: 983 GSFPTDKEEEDEEEEFGDFRLVSNDNEFDSDEDEHSDSGNDLALEDHEDDDEEELLKRS- 1041 Query: 206 LNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLD 252 K+ R E E + S+ +D E + E +D Sbjct: 1042 ---EKLKRQMRLRKYLEDEAEVSGSDVGSEDEYDGEEIDEYEEDVID 1085 Score = 30.8 bits (68), Expect = 8.0 Identities = 17/78 (21%), Positives = 42/78 (53%), Gaps = 2/78 (2%) Query: 69 QEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEE-DEGEEYSEDNDEPGDEDEEDEEG 127 +E + + +++ ++ + + E+++E+EE +E EE E N E + EE Sbjct: 629 EEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEE-EEEEEGNQETAEFLLSSEEI 687 Query: 128 DREEEEEIEEEDEDDDED 145 + ++E+E+++E+ D + Sbjct: 688 ETKDEKEMDKENNDGSSE 705 >gi|21735415 centromere protein B [Homo sapiens] Length = 599 Score = 68.6 bits (166), Expect = 3e-11 Identities = 40/125 (32%), Positives = 65/125 (52%), Gaps = 21/125 (16%) Query: 96 TEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEE---DEDDDEDGEDVEDE 152 T + + E+E EE E+ +E G+ +EE+EEG+ EEEE E E +E++ E+ DV+ + Sbjct: 398 TTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSD 457 Query: 153 EEEEEEEEEEEEEEENED------------------HQMNCHNTRIMQDTEKDDNNNDEY 194 EEEEE+EE E E ED + C ++ E D++++E Sbjct: 458 EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517 Query: 195 DNYDE 199 D+ +E Sbjct: 518 DDEEE 522 Score = 66.6 bits (161), Expect = 1e-10 Identities = 46/142 (32%), Positives = 75/142 (52%), Gaps = 11/142 (7%) Query: 104 EDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEE 163 + EGEE E+ +E+EE+EEG+ EEEEE EE+E++ +GE++ +EEE EEE + + Sbjct: 402 KSEGEEEEEE-----EEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDS 456 Query: 164 EEEENEDHQMNCHNTRI---MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRAR 220 +EEE ED + + Q + + Y +E +L L + ED+ + Sbjct: 457 DEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFL-EGGEDS--DSD 513 Query: 221 TESEMNSNTSNSLEDDSDKNEN 242 +E E + + EDD D E+ Sbjct: 514 SEEEDDEEEDDEDEDDDDDEED 535 Score = 53.9 bits (128), Expect = 9e-07 Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 27/138 (19%) Query: 59 KKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPG 118 K ++++ +E + + + + +E ++ E++ E+EE E EE D+DE Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVE-EEGDVDSDEEE 460 Query: 119 DEDEEDEEGDREEEEEIE--------------------------EEDEDDDEDGEDVEDE 152 +EDEE E E+ + E ED D D E+ +DE Sbjct: 461 EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDE 520 Query: 153 EEEEEEEEEEEEEEENED 170 EE++E+E+++++EE+ ++ Sbjct: 521 EEDDEDEDDDDDEEDGDE 538 Score = 38.9 bits (89), Expect = 0.029 Identities = 18/44 (40%), Positives = 29/44 (65%), Gaps = 9/44 (20%) Query: 106 EGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDV 149 EG E S+ + E D++EED+E +E+D+DD+EDG++V Sbjct: 505 EGGEDSDSDSEEEDDEEEDDE---------DEDDDDDEEDGDEV 539 >gi|21361639 DIPB protein [Homo sapiens] Length = 344 Score = 68.6 bits (166), Expect = 3e-11 Identities = 42/111 (37%), Positives = 60/111 (54%), Gaps = 5/111 (4%) Query: 93 SDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152 +DG E+ E + E+ E E G+E E +EE + EEE E EEE E D+ D E ED Sbjct: 71 ADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESE-DESDEESEEDS 129 Query: 153 EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203 EEE E+E+E E EE+N++ + +TE + + E + E VAK Sbjct: 130 EEEMEDEQESEAEEDNQEE----GESEAEGETEAESEFDPEIEMEAERVAK 176 Score = 62.4 bits (150), Expect = 2e-09 Identities = 31/75 (41%), Positives = 46/75 (61%) Query: 92 DSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVED 151 +S+ E+ + +EE E EE SE +E DE +E+ E D EEE E E+E E ++++ E+ E Sbjct: 92 ESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGES 151 Query: 152 EEEEEEEEEEEEEEE 166 E E E E E E + E Sbjct: 152 EAEGETEAESEFDPE 166 Score = 58.9 bits (141), Expect = 3e-08 Identities = 34/79 (43%), Positives = 48/79 (60%), Gaps = 3/79 (3%) Query: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVE 150 ++S+ E+ + +EE E EE SED E +E EED E + E+E+E E E ED+ E+GE Sbjct: 97 EESESEEESESEEESETEEESED--ESDEESEEDSEEEMEDEQESEAE-EDNQEEGESEA 153 Query: 151 DEEEEEEEEEEEEEEEENE 169 + E E E E + E E E E Sbjct: 154 EGETEAESEFDPEIEMEAE 172 Score = 52.0 bits (123), Expect = 3e-06 Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 13/127 (10%) Query: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEP 117 A K + + K QE R+ + + S +E +S+ + +E+ EDE +E SE++ E Sbjct: 76 AGKEEAEVKVEQE----REIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEE 131 Query: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN--------- 168 EDE++ E + + +EE E E E + E + + E E E E + + ++ Sbjct: 132 EMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQ 191 Query: 169 EDHQMNC 175 ED Q+ C Sbjct: 192 EDRQLIC 198 Score = 48.5 bits (114), Expect = 4e-05 Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Query: 122 EEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE-EEEEEEEEEEENEDHQMNCHNTRI 180 +E+ E E+E EIE E ++ E E+ E EEE E EEE E+E +EE+E+ Sbjct: 78 KEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQ 137 Query: 181 MQDTEKDDNNNDEYDNYDELVAKS 204 + E+D+ E + E A+S Sbjct: 138 ESEAEEDNQEEGESEAEGETEAES 161 >gi|22749303 hypothetical protein LOC196477 [Homo sapiens] Length = 406 Score = 68.6 bits (166), Expect = 3e-11 Identities = 39/83 (46%), Positives = 57/83 (68%), Gaps = 4/83 (4%) Query: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156 E+ +EK+ D+ EEY ++ + + EE+EE + +EEEE+E+E+E++ E+ E VE+ EEE Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVE-DEEEEVEDEEEEEVEEAEYVEEGEEEL 335 Query: 157 EEEE-EEEEE--EENEDHQMNCH 176 EEEE EEEEE EENE H Sbjct: 336 EEEELEEEEEVLEENEQRGEEFH 358 Score = 53.9 bits (128), Expect = 9e-07 Identities = 33/97 (34%), Positives = 50/97 (51%), Gaps = 10/97 (10%) Query: 77 PFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIE 136 P V+ + ++ ++ E D KE E EE ED +E +++EE+E + E EE E Sbjct: 273 PLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGE 332 Query: 137 EEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQM 173 EE +E+EE EEEEE EE E+ E+ + Sbjct: 333 EE----------LEEEELEEEEEVLEENEQRGEEFHL 359 Score = 48.9 bits (115), Expect = 3e-05 Identities = 32/80 (40%), Positives = 47/80 (58%), Gaps = 6/80 (7%) Query: 108 EEYSEDNDEPGDEDEEDEEG-DREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEE 166 EE + ND DE+E D+E D +E E EEE ED++E+ ED +EEEE EE E EE E Sbjct: 278 EEEEKKND---DEEEYDQEVCDAKEASEEEEEVEDEEEEVED--EEEEEVEEAEYVEEGE 332 Query: 167 ENEDHQMNCHNTRIMQDTEK 186 E + + ++++ E+ Sbjct: 333 EELEEEELEEEEEVLEENEQ 352 Score = 48.5 bits (114), Expect = 4e-05 Identities = 28/81 (34%), Positives = 46/81 (56%), Gaps = 5/81 (6%) Query: 122 EEDEEGDREEEEEIEEE---DEDDDEDGEDVEDEEEE--EEEEEEEEEEEENEDHQMNCH 176 EE+EE ++EEE ++E ++ E+ E+VEDEEEE +EEEEE EE E E+ + Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336 Query: 177 NTRIMQDTEKDDNNNDEYDNY 197 + ++ E + N + + Sbjct: 337 EEELEEEEEVLEENEQRGEEF 357 Score = 43.9 bits (102), Expect = 0.001 Identities = 22/56 (39%), Positives = 34/56 (60%) Query: 117 PGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172 P E+ + EEEE ++ D++++ D E + +E EEEEE E+EEEE ED + Sbjct: 263 PNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEE 318 Score = 43.5 bits (101), Expect = 0.001 Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 6/90 (6%) Query: 56 PLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND 115 PL + + + K E ++ K S +E +D + + +E+EE E EY E+ Sbjct: 273 PLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEG- 331 Query: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDED 145 +EE EE + EEEEE+ EE+E E+ Sbjct: 332 -----EEELEEEELEEEEEVLEENEQRGEE 356 Score = 40.8 bits (94), Expect = 0.008 Identities = 29/126 (23%), Positives = 54/126 (42%), Gaps = 31/126 (24%) Query: 135 IEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEY 194 +EEE+E ++D E+ + E + +E EEEEE E+E+ + ++D E+++ Sbjct: 276 VEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEE--------VEDEEEEE------ 321 Query: 195 DNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLD 254 E+A Y E E+ E+ ++NE G + L L++ Sbjct: 322 -----------------VEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMP 364 Query: 255 SDVVRE 260 + E Sbjct: 365 LSIFVE 370 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 68.2 bits (165), Expect = 5e-11 Identities = 112/657 (17%), Positives = 217/657 (33%), Gaps = 35/657 (5%) Query: 81 KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDED-----EEDEEGDREEEEEI 135 K+DSS D D S+ ++ D + D + S + + D D + D + Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605 Query: 136 EEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNN---- 191 + D D D D D + + + E + + +++ + +++ +++ D++N Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665 Query: 192 ----DEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNS-LEDDSDKNENLGRK 246 D D+ D + N ++ + +ES +S++S+S D SD + + Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725 Query: 247 SELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSR----NMNYVML 302 S+ S DS + DS + S++ + N +DS DS + N Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785 Query: 303 GKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVR 362 N+ SD S + + D + +N + + N + Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845 Query: 363 PEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEE 422 D + N SD N S S S D D + +S +SD S+ Sbjct: 846 DSSD-GSDSDSSNRSDSSN-------SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897 Query: 423 VFDMTKGNLTLLEKAIALETERAKAMRE--KMAMEAGRRDNMRSYEDQSPRQLPGEDRKP 480 + + + ++ + E + + D+ S + Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957 Query: 481 KSSDSHVKKPYYDPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILA 540 SSDS D + ++ +S + D + S S + Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017 Query: 541 MHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASD 600 +S + + + + +S S + + + + + S D S SS +SD Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077 Query: 601 RVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIA 660 E +N ++ S+ + + + +S +++ + Sbjct: 1078 S-------SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130 Query: 661 PKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSS 717 + D S D S SS S+ S S SS+ S SS SS S SS Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1187 Score = 63.9 bits (154), Expect = 9e-10 Identities = 106/637 (16%), Positives = 215/637 (33%), Gaps = 33/637 (5%) Query: 82 ADSSSVDECDDSDGTEDMDEKEED-EGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE 140 +DS ++ DDSD T D + + + G ++DND+ + + D + + D Sbjct: 505 SDSKGAED-DDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDS 563 Query: 141 DDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDEL 200 D D + + + + + + + ++ + N+ D+ +++D D+ D Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSD-- 621 Query: 201 VAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRE 260 S + K D+ ++S+ S++S+S DS N + S S DS + Sbjct: 622 ---SKSDSSKSESDS-----SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSD 673 Query: 261 TVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDE 320 + DS + S++ + N ++S DS + + N+ SD Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS-------NSSDS 726 Query: 321 EVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDML 380 + SS + D + +N + + + + D + N SD Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786 Query: 381 NLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIAL 440 + + + +S + + D+ S NS S D + + + + Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNS------SD 840 Query: 441 ETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKSSDSHVKKPYYDPSRTEKK 500 ++ + + + + R D+ S + SSDS+ D S + Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900 Query: 501 ESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVN 560 + + + S S + + +S + + + + Sbjct: 901 SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960 Query: 561 SNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYR 620 + NS S S + + + + + S D S SS +SD + Sbjct: 961 DSSNSSDS-SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS-------SNSSDSSDSSDS 1012 Query: 621 NNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYC 680 ++ ++ SN + + +S + + + + D S Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072 Query: 681 KDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSS 717 D S SS S+ S S SSN S SS SS S SS Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109 Score = 56.6 bits (135), Expect = 1e-07 Identities = 113/656 (17%), Positives = 229/656 (34%), Gaps = 62/656 (9%) Query: 71 PAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEED-EGEEYSEDNDEPGDED---EEDEE 126 P K +P K S+ +SDG + D ++ +G++ + ++ G++D E D Sbjct: 426 PGQKSEP-GNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNN 484 Query: 127 GDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEK 186 + ++ D+ +G D + E+++ + + ++ + N ++ D+ K Sbjct: 485 SSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGK 544 Query: 187 DDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRK 246 +++ + D+ D + + + + +S++S+S + DS + N Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS 604 Query: 247 SELSLDLD----SDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMNYVML 302 S+ S D SD DS K + + +D N +DS DS + + Sbjct: 605 SDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS---- 660 Query: 303 GKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIRQHVR 362 N+ + SD SS + + S + N ++ + Sbjct: 661 ----NSSNSSDSSDSSDSSDSSSSSDSSNSSD-------SSDSSDSSNSSESSDSSDSSD 709 Query: 363 PEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCAKEDGCHERDDDTTSVNSDRSEE 422 + + + N SD + + S S + + + D + S NS S + Sbjct: 710 SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769 Query: 423 VFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQLPGEDRKPKS 482 D + + + + ++ + + ++ + + D S + S Sbjct: 770 SSDSSDSSDS------SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS 823 Query: 483 SDSHVKKPYYDPSR-TEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRVPPEILAM 541 SDS D S ++ +S + G D +RS S + Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDS-------SNRSDSSNSSDSSDSSDSSNS 876 Query: 542 HESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQSCDVSKSSQASDR 601 +S + + + + NS S S + + + + + S D S+SS +SD Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDS----SDSSNSSDSSDSSNSSDSSESSNSSD- 931 Query: 602 VLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKYSKTSFEYNSYDNHTYGKRAIAP 661 N+ + + S+ + + S +S NS D+ + + Sbjct: 932 -------------------NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972 Query: 662 KVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGGSSASSTCSKSS 717 + D S D S SS S++S S SS+ S SS SS S SS Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028 Score = 53.5 bits (127), Expect = 1e-06 Identities = 27/173 (15%), Positives = 68/173 (39%), Gaps = 2/173 (1%) Query: 84 SSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD 143 S S + D SD ++ D + + S+ ++ D D + + + D D Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177 Query: 144 EDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAK 203 + D D + + + + + ++ + ++ D+ +++D D+ D + Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS--DSSDSSDSSDSSDSSDSSDSSDSNESS 1235 Query: 204 SLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSD 256 + ++ + ++S +S++++ D+SD G + D DSD Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288 Score = 52.0 bits (123), Expect = 3e-06 Identities = 23/115 (20%), Positives = 47/115 (40%), Gaps = 2/115 (1%) Query: 84 SSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD 143 S S D D SD ++ D + + + S+ +D D D E + + D D Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246 Query: 144 EDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKD--DNNNDEYDN 196 + D D + + + +E +++ N +N D++ + D+N+ D+ Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301 Score = 43.5 bits (101), Expect = 0.001 Identities = 128/678 (18%), Positives = 223/678 (32%), Gaps = 94/678 (13%) Query: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEE-EEIEEEDEDDDEDGEDV 149 D+SDG+ + +EDE E +D DE ++ + +E ++ +ED+ D G++ Sbjct: 240 DNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNS 299 Query: 150 EDEEEEEEEEEEE----------EEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199 + +E + E +E+ + EEN + ++ ++DT+K N+ E + Sbjct: 300 DSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQK--LNHRESKRVEN 357 Query: 200 LVAKSLLN--LGKIAEDAAYRARTESEMNSNTSNSL----EDDSDKN------------- 240 + K +GK ++D + S N N + + E DK Sbjct: 358 RITKESETHAVGK-SQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKT 416 Query: 241 -------ENLGRKSE---------LSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRN 284 E G+KSE D +SD ++ D QG S+ N + Sbjct: 417 QGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGY-DSYDFDDKSMQGDDPNSSDESNGND 475 Query: 285 YADSMSQQDSRNMNYVML----GKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARK 340 A+S S +S + K NG K E+ D + Sbjct: 476 DANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD------------------S 517 Query: 341 LSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSRVFASCA 400 S+TN + N N +D + SD + + S S + Sbjct: 518 TSDTNNSDSNGNGN-------NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD 570 Query: 401 KEDGCHERDDDTTSVNSDRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRD 460 D D D++ +S S + N + + ++ + + + D Sbjct: 571 SSDSNSSSDSDSSDSDSSDSSDSDSSDSSN-----SSDSSDSSDSSDSSDSSDSSDSKSD 625 Query: 461 NMRSYEDQSPRQLPGEDRKPKSSDSHVKKPYYDPSR-TEKKESKCPTPGCDGTGHVTGLY 519 + +S D S + SSDS D S + +S + D + Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685 Query: 520 PHHRSLSGCPHKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEK 579 S S + +S + + + NS S + + Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745 Query: 580 LAKAQEKHQSCDVSKSSQASDRVLRPMCFVKQLEIPQYGYRNNVPTTTPRSNLAKELEKY 639 + + S D S SS +SD + +N + SN + + Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDS-------SDSSDSSDSSDSSNSSDSNDSSN-SSDSSDS 797 Query: 640 SKTSFEYNSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSS 699 S +S NS D+ + + + D S D + S SS +S + S SS Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSD-SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856 Query: 700 NLSCGGGSSASSTCSKSS 717 N S SS SS S SS Sbjct: 857 NRSDSSNSSDSSDSSDSS 874 Score = 40.8 bits (94), Expect = 0.008 Identities = 32/156 (20%), Positives = 72/156 (46%), Gaps = 18/156 (11%) Query: 104 EDEGEEYSEDNDEPGDEDEEDEE--GDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE 161 ED G + S+ + DE+++E GD E+EE +D ++ G++ +D +E++ + Sbjct: 235 EDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSS 294 Query: 162 EEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAED-AAYRAR 220 + +++++ D E ++ ++E D + +KS N I ED + R Sbjct: 295 IGQNSDSKEY----------YDPEGKEDPHNEVDG--DKTSKSEENSAGIPEDNGSQRIE 342 Query: 221 TESEMNSNTSNSLEDDSDKNEN---LGRKSELSLDL 253 ++N S +E+ K +G+ + +++ Sbjct: 343 DTQKLNHRESKRVENRITKESETHAVGKSQDKGIEI 378 Score = 38.1 bits (87), Expect = 0.050 Identities = 17/84 (20%), Positives = 34/84 (40%), Gaps = 2/84 (2%) Query: 82 ADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDED 141 +DSS D SD E D + + + S +D D D D +E + + + + Sbjct: 1220 SDSSDSS--DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGN 1277 Query: 142 DDEDGEDVEDEEEEEEEEEEEEEE 165 + +G D + + E + ++ Sbjct: 1278 GNNNGSDSDSDSEGSDSNHSTSDD 1301 Score = 37.4 bits (85), Expect = 0.085 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%) Query: 95 GTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEG----DREEEEEIEEEDEDDDEDGEDVE 150 G ++ D G + ED DEDEE G + + +E ++ ++DD D + Sbjct: 238 GLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQ 297 Query: 151 DEEEEEEEEEEEEEEEENE 169 + + +E + E +E+ NE Sbjct: 298 NSDSKEYYDPEGKEDPHNE 316 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 67.8 bits (164), Expect = 6e-11 Identities = 39/110 (35%), Positives = 58/110 (52%), Gaps = 7/110 (6%) Query: 91 DDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGD--REEEEEIEEEDEDDDEDGED 148 D SD E E S +E +E+EE+EEG E EEE EEE+E+++E G + Sbjct: 256 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 315 Query: 149 VED-----EEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDE 193 E+ EE EEE E+EE ENE+H + +R +D+ + + +E Sbjct: 316 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEE 365 Score = 64.3 bits (155), Expect = 7e-10 Identities = 51/188 (27%), Positives = 83/188 (44%), Gaps = 17/188 (9%) Query: 47 ARHRSVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDE--CDDSDGTEDMDEKEE 104 A HR++ + K K P P R+ F + V E ++ D D+ + + Sbjct: 201 AHHRTMRE-DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISD 259 Query: 105 DEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEE 164 E + S E E G EEEE EE+E+++E+G E+ EEEEEEEEEEEE Sbjct: 260 SERKTSSA-------ESSSAESGSGSEEEE--EEEEEEEEEGSTSEESEEEEEEEEEEEE 310 Query: 165 EEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESE 224 E + + + + + + E ++ E +N+ +V +S + D+ E E Sbjct: 311 ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES-----RFDRDSGESEEAEEE 365 Query: 225 MNSNTSNS 232 + T S Sbjct: 366 VGEGTPQS 373 Score = 43.9 bits (102), Expect = 0.001 Identities = 41/186 (22%), Positives = 77/186 (41%), Gaps = 19/186 (10%) Query: 59 KKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPG 118 K R+ Q +Q ++ +R+ + + + E T D ++ + +S P Sbjct: 168 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPP 227 Query: 119 DEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE-----------EEEEEEEEEEEEEE 167 E E +G + +EE + E+ D D +D+ D E E EEEEEEEE Sbjct: 228 RERFELGDGRKPVKEE-KMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 286 Query: 168 NEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNS 227 E+ + + ++ E+++ + N +E +S AE+ + +E E Sbjct: 287 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-------AEEVSEEEMSEDEERE 339 Query: 228 NTSNSL 233 N ++ L Sbjct: 340 NENHLL 345 Score = 37.0 bits (84), Expect = 0.11 Identities = 68/371 (18%), Positives = 125/371 (33%), Gaps = 33/371 (8%) Query: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGD-------REEEEEIEEEDEDDDEDGEDV 149 ++ +EK E + + S+D D D EE E D R E+ ED E+ + + Sbjct: 24 KEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL 83 Query: 150 EDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQ-DTEKDDNNNDEYDNYDELVAKSLLNL 208 + ++ +E+ ++E + + R+ + + E+ + +E D A+ Sbjct: 84 AIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDK-----ARREWER 138 Query: 209 GKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDSLKLL 268 K E A +R E + E + E + E R + Sbjct: 139 QKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 198 Query: 269 AQGHGVVLSENMNDRNYADSMSQQDSRNMNYVMLGKPMNNGLMEKMVEESDEEVCLSSLE 328 H + E+ +D+ A S+ R + +G E+ +E LS L+ Sbjct: 199 VSAHHRTMREDYSDKVKASHWSRSPPRPPRERF---ELGDGRKPVKEEKMEERDLLSDLQ 255 Query: 329 CLRNQCFDLARKLSETNPQERNPQQNMNIRQHVRPEEDFPGRTPDRNYSDMLNLMRLEEQ 388 + D RK S + EE+ G T + + + EE+ Sbjct: 256 DIS----DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEE 311 Query: 389 LSPRSRVFASCAKEDGCHERDDDTTSVNSDRS---------EEVFDMTKGNLTLLEKAIA 439 S A E E ++ S + +R E FD G E+ + Sbjct: 312 TGSNSEE----ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVG 367 Query: 440 LETERAKAMRE 450 T ++ A+ E Sbjct: 368 EGTPQSSALTE 378 Score = 30.8 bits (68), Expect = 8.0 Identities = 51/306 (16%), Positives = 111/306 (36%), Gaps = 34/306 (11%) Query: 51 SVYGCPLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTED-----MDEKEED 105 ++ P ++ +D+ ++ + KP + V D E + E+E + Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE 120 Query: 106 EGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEE 165 + + E+ D+ E E + + E E D + + + + + E+++E+ E++ Sbjct: 121 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK 180 Query: 166 E----------ENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLG------ 209 E E E + + R M++ D + + LG Sbjct: 181 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 240 Query: 210 --------KIAEDAAYRARTESEMNSNTSNSLEDDS----DKNENLGRKSELSLDLDSDV 257 + D + +E + +S S+S E S ++ E + E S +S+ Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300 Query: 258 VRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSR-NMNYVMLGKPMNNGLMEKMVE 316 E + + + SE + + MS+ + R N N++++ E Sbjct: 301 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE 360 Query: 317 ESDEEV 322 E++EEV Sbjct: 361 EAEEEV 366 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.127 0.363 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 51,394,195 Number of Sequences: 37866 Number of extensions: 2860871 Number of successful extensions: 99929 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1258 Number of HSP's successfully gapped in prelim test: 753 Number of HSP's that attempted gapping in prelim test: 25512 Number of HSP's gapped (non-prelim): 26751 length of query: 1184 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1071 effective length of database: 13,968,660 effective search space: 14960434860 effective search space used: 14960434860 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.