BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sapiens] (823 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 1621 0.0 gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 1615 0.0 gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 1608 0.0 gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 1599 0.0 gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 1417 0.0 gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 1417 0.0 gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 472 e-133 gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 472 e-133 gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 471 e-132 gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 378 e-104 gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 378 e-104 gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 377 e-104 gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 375 e-104 gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 369 e-102 gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 369 e-102 gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 369 e-102 gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 328 2e-89 gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 284 2e-76 gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 274 3e-73 gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 272 8e-73 gi|153791352 prostate, ovary, testis expressed protein on chromo... 270 3e-72 gi|134133226 protein expressed in prostate, ovary, testis, and p... 270 4e-72 gi|113413200 PREDICTED: similar to protein expressed in prostate... 266 4e-71 gi|88953571 PREDICTED: similar to protein expressed in prostate,... 265 1e-70 gi|239741769 PREDICTED: similar to protein expressed in prostate... 248 2e-65 gi|239741786 PREDICTED: kappa-actin [Homo sapiens] 246 6e-65 gi|239753333 PREDICTED: actin, beta-like 3 [Homo sapiens] 246 8e-65 gi|239747898 PREDICTED: actin, beta-like 3 [Homo sapiens] 246 8e-65 gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo... 240 4e-63 gi|52856434 POTE ankyrin domain family, member G [Homo sapiens] 231 2e-60 >gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sapiens] Length = 823 Score = 1621 bits (4197), Expect = 0.0 Identities = 823/823 (100%), Positives = 823/823 (100%) Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 Query: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI Sbjct: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 Query: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 Query: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN Sbjct: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600 Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660 Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 Query: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823 >gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sapiens] Length = 823 Score = 1615 bits (4181), Expect = 0.0 Identities = 821/823 (99%), Positives = 821/823 (99%) Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 Query: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI Sbjct: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 Query: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 Query: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN Sbjct: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELN LKAENTRLNAELLKEKESKK Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600 Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660 Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 Query: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRK I Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKKI 823 >gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sapiens] Length = 823 Score = 1608 bits (4164), Expect = 0.0 Identities = 818/823 (99%), Positives = 819/823 (99%) Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 DALDKQHRTALHLAC SGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL Sbjct: 61 DALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 Query: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 MVEFLLK+KASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI Sbjct: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 Query: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK Sbjct: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 Query: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 PTVQSLEMKSKTARNTPN DFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN Sbjct: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELN LKAENTRLNAELLKEKESKK Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600 Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVK ENEFL Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKAENEFL 660 Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 Query: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823 >gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sapiens] Length = 823 Score = 1599 bits (4141), Expect = 0.0 Identities = 813/823 (98%), Positives = 818/823 (99%) Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSG+L Sbjct: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGEL 60 Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL Sbjct: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 Query: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 MVEFLLK+KASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI Sbjct: 181 MVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC Sbjct: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA Sbjct: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 Query: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 EQALPVASEEEQ+RHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK Sbjct: 361 EQALPVASEEEQQRHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 Query: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 PTVQSLEMKSKTARNTPN DFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN Sbjct: 481 PTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELN LKAENTRLNAELLKEKESKK Sbjct: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKK 600 Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERT+DVSVQVEMSSAISKVKDENEFL Sbjct: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTQDVSVQVEMSSAISKVKDENEFL 660 Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQN+LSQTQQQTQEMKEMYQNAEAKV Sbjct: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAEAKV 720 Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKD VLEE Sbjct: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDFVLEE 780 Query: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823 KSKKLMNECDHLKESLFQYEREKTE VVSIKEDKYFQTSRK I Sbjct: 781 KSKKLMNECDHLKESLFQYEREKTEVVVSIKEDKYFQTSRKKI 823 >gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5 [Homo sapiens] Length = 823 Score = 1417 bits (3668), Expect = 0.0 Identities = 726/823 (88%), Positives = 768/823 (93%) Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 MKLFGF SRRGQT GSIDH+YTGSGYRIR SELQKIH+AAVKGDAAE+ERCLARRSGDL Sbjct: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60 Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 DALDKQHRTALHLACASGHV+VVTLLVNRKCQID+ DKENRTPLIQAVHCQEEACAVILL Sbjct: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120 Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLL HG +IEALDKD+NTPLLFAIICKKEK Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180 Query: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 MVEFLLK KAS+HAVDRLR +ALMLAV+YDS GIVNILLKQ+I+VF QDMCGRDAEDYAI Sbjct: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240 Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 S LTKIQQQILEHKK ILK +K DVGSSDESAVSIFHEL VDSL A DD+ L+VA KQC Sbjct: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300 Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 VPEKVSEPL G SH KGNRIVNG+GEGPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRA Sbjct: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360 Query: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 EQALPVASEEEQ+R ERSEKKQPQV EGNNT KSEKIQLSENIC ST SAAA RLTQQRK Sbjct: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420 Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNML+KKNREELERKEKQYKKEVEAKQLE Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480 Query: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 PTVQSLEMK KTARNTPN+DFHNHEE+K LMDENCILK DIAILRQEICTMKNDNLEKEN Sbjct: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540 Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600 KYLKDIKI KETNAALEK IKLNEEMIT+TAF YQQELN LKAENTRLN+ELLKEKESKK Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600 Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660 +LEA+IESYQSRLAAAISKHSE+VKTERNLKLALERT+D+S QV+MSS IS+++D+N FL Sbjct: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660 Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 TEQLS+ QIKFN LKDKFRKTRD+LRKKSLALETVQNDLSQTQQQ +EMKEMYQ+AEAKV Sbjct: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720 Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 + STGKWNCVEERIC LQREN WL QQL DVHQKEDHKEIV NIQRGFIES KKDL+LEE Sbjct: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780 Query: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823 K+KKLMNE DHLKESLFQYER+K E VVSIKEDKYFQTSRK + Sbjct: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823 >gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5 [Homo sapiens] Length = 823 Score = 1417 bits (3668), Expect = 0.0 Identities = 726/823 (88%), Positives = 768/823 (93%) Query: 1 MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDL 60 MKLFGF SRRGQT GSIDH+YTGSGYRIR SELQKIH+AAVKGDAAE+ERCLARRSGDL Sbjct: 1 MKLFGFRSRRGQTVLGSIDHLYTGSGYRIRYSELQKIHKAAVKGDAAEMERCLARRSGDL 60 Query: 61 DALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILL 120 DALDKQHRTALHLACASGHV+VVTLLVNRKCQID+ DKENRTPLIQAVHCQEEACAVILL Sbjct: 61 DALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTPLIQAVHCQEEACAVILL 120 Query: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEK 180 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLL HG +IEALDKD+NTPLLFAIICKKEK Sbjct: 121 EHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALDKDSNTPLLFAIICKKEK 180 Query: 181 MVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAI 240 MVEFLLK KAS+HAVDRLR +ALMLAV+YDS GIVNILLKQ+I+VF QDMCGRDAEDYAI Sbjct: 181 MVEFLLKNKASTHAVDRLRXTALMLAVHYDSLGIVNILLKQSINVFTQDMCGRDAEDYAI 240 Query: 241 SHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQC 300 S LTKIQQQILEHKK ILK +K DVGSSDESAVSIFHEL VDSL A DD+ L+VA KQC Sbjct: 241 SCRLTKIQQQILEHKKMILKNDKPDVGSSDESAVSIFHELCVDSLSALDDELLSVAAKQC 300 Query: 301 VPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRA 360 VPEKVSEPL G SH KGNRIVNG+GEGPPAKHPSLKPSTE+EDPAVKGAVQ KNVQTLRA Sbjct: 301 VPEKVSEPLRGPSHGKGNRIVNGKGEGPPAKHPSLKPSTEMEDPAVKGAVQXKNVQTLRA 360 Query: 361 EQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 EQALPVASEEEQ+R ERSEKKQPQV EGNNT KSEKIQLSENIC ST SAAA RLTQQRK Sbjct: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420 Query: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLE 480 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNML+KKNREELERKEKQYKKEVEAKQLE Sbjct: 421 IGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEVEAKQLE 480 Query: 481 PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKEN 540 PTVQSLEMK KTARNTPN+DFHNHEE+K LMDENCILK DIAILRQEICTMKNDNLEKEN Sbjct: 481 PTVQSLEMKPKTARNTPNQDFHNHEEVKDLMDENCILKTDIAILRQEICTMKNDNLEKEN 540 Query: 541 KYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKK 600 KYLKDIKI KETNAALEK IKLNEEMIT+TAF YQQELN LKAENTRLN+ELLKEKESKK Sbjct: 541 KYLKDIKIAKETNAALEKCIKLNEEMITKTAFWYQQELNDLKAENTRLNSELLKEKESKK 600 Query: 601 RLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFL 660 +LEA+IESYQSRLAAAISKHSE+VKTERNLKLALERT+D+S QV+MSS IS+++D+N FL Sbjct: 601 KLEAEIESYQSRLAAAISKHSENVKTERNLKLALERTQDISEQVKMSSDISEIEDKNXFL 660 Query: 661 TEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKV 720 TEQLS+ QIKFN LKDKFRKTRD+LRKKSLALETVQNDLSQTQQQ +EMKEMYQ+AEAKV Sbjct: 661 TEQLSKMQIKFNTLKDKFRKTRDTLRKKSLALETVQNDLSQTQQQIKEMKEMYQSAEAKV 720 Query: 721 NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEE 780 + STGKWNCVEERIC LQREN WL QQL DVHQKEDHKEIV NIQRGFIES KKDL+LEE Sbjct: 721 SKSTGKWNCVEERICQLQRENPWLEQQLVDVHQKEDHKEIVINIQRGFIESRKKDLMLEE 780 Query: 781 KSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI 823 K+KKLMNE DHLKESLFQYER+K E VVSIKEDKYFQTSRK + Sbjct: 781 KNKKLMNEYDHLKESLFQYERQKAETVVSIKEDKYFQTSRKKV 823 >gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] Length = 917 Score = 472 bits (1215), Expect = e-133 Identities = 312/839 (37%), Positives = 472/839 (56%), Gaps = 68/839 (8%) Query: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQ 81 ++ GYR+R +L IH+AA+ GD +V + R DL+ DK++RTAL LACA G Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 Query: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 Query: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRLRRS 201 +E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLK+K A+D R+ Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206 Query: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261 AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+ Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264 Query: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317 KS S+ E + + E + L S + K+C +K VS + + Sbjct: 265 RKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324 Query: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQTL--------RAEQAL 364 N +++ P H S K + E + A K + ++ V++ + Sbjct: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384 Query: 365 PVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK---- 420 SE+++ + E +K+ K + + LS++ ++AA GR + +K Sbjct: 385 EKTSEDDELPYSDDENFMLLIKQSGMECK-DFVSLSKS---KNATAACGRSIEDQKCYCE 440 Query: 421 ---------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM 454 + K + K + EH R L+Q+ EE+ Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 Query: 455 LYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDE 513 LY+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N++FH HE + L E Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 Query: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573 N +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T R Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 Query: 574 YQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633 Y +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Query: 634 LERTRD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLA 691 + T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L Sbjct: 681 FQSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLH 733 Query: 692 LETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV 751 +E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D Sbjct: 734 IEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDA 793 Query: 752 HQKEDHKE-IVTNIQRGFIESGKKDLV----LEEKSKKLMNECDHLKESLFQYEREKTE 805 +K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E Sbjct: 794 RKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852 >gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo sapiens] Length = 917 Score = 472 bits (1215), Expect = e-133 Identities = 312/839 (37%), Positives = 472/839 (56%), Gaps = 68/839 (8%) Query: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQ 81 ++ GYR+R +L IH+AA+ GD +V + R DL+ DK++RTAL LACA G Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 Query: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 Query: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRLRRS 201 +E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLK+K A+D R+ Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRT 206 Query: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261 AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+ Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264 Query: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317 KS S+ E + + E + L S + K+C +K VS + + Sbjct: 265 RKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324 Query: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQTL--------RAEQAL 364 N +++ P H S K + E + A K + ++ V++ + Sbjct: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384 Query: 365 PVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK---- 420 SE+++ + E +K+ K + + LS++ ++AA GR + +K Sbjct: 385 EKTSEDDELPYSDDENFMLLIKQSGMECK-DFVSLSKS---KNATAACGRSIEDQKCYCE 440 Query: 421 ---------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM 454 + K + K + EH R L+Q+ EE+ Sbjct: 441 RLKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEE 500 Query: 455 LYKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDE 513 LY+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N++FH HE + L E Sbjct: 501 LYEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQE 560 Query: 514 NCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573 N +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T R Sbjct: 561 NHLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITR 620 Query: 574 YQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633 Y +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA Sbjct: 621 YSKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLA 680 Query: 634 LERTRD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLA 691 + T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L Sbjct: 681 FQSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLH 733 Query: 692 LETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV 751 +E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D Sbjct: 734 IEHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDA 793 Query: 752 HQKEDHKE-IVTNIQRGFIESGKKDLV----LEEKSKKLMNECDHLKESLFQYEREKTE 805 +K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E Sbjct: 794 RKKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852 >gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo sapiens] Length = 917 Score = 471 bits (1211), Expect = e-132 Identities = 311/838 (37%), Positives = 470/838 (56%), Gaps = 66/838 (7%) Query: 22 YTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQ 81 ++ GYR+R +L IH+AA+ GD +V + R DL+ DK++RTAL LACA G Sbjct: 27 FSNPGYRVRQKDLGMIHKAAIAGDVNKVMESILLRLNDLNDRDKKNRTALLLACAHGRPG 86 Query: 82 VVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAV 141 VV LV RKCQ+++ D ENRT LI+AV CQEE CA ILLEHGANPN++D+YGNTALHYA+ Sbjct: 87 VVADLVARKCQLNLTDSENRTALIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAI 146 Query: 142 YSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRLRRS 201 +E+ S+A KLL++GA IEA +D +T LL A+ KKE+MV FLLK+K A+D R+ Sbjct: 147 DNENISMARKLLAYGADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRT 206 Query: 202 ALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKK 261 AL+LA S +V LL+ NIDVF QD+ G AEDYA++ I+ I E+K K+ Sbjct: 207 ALILAARNGSTSVVYQLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKAN--KR 264 Query: 262 EKSDVGSSDESAVSIFHELRVDSLPA--SDDKDLNVATKQCVPEK--VSEPLPGSSHEKG 317 KS S+ E + + E + L S + K+C +K VS + + Sbjct: 265 CKSLQNSNSEQDLEMTSEGEQERLEGCESSQPQVEEKMKKCRNKKMEVSRNVHADDSDNY 324 Query: 318 N----RIVNGQGEGPPAKHPSL-KPSTEVEDPAVKGAVQRKNVQT-------LRAEQALP 365 N +++ P H S K + E + A K + ++ V++ L Sbjct: 325 NDDVDELIHKIKNRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSS 384 Query: 366 VASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK----- 420 + E+ E ++ + E + + + LS++ ++AA GR + +K Sbjct: 385 EKTSEDDELPYSDDENFMLLIEQSGMECKDFVSLSKS---KNATAACGRSIEDQKCYCER 441 Query: 421 --------------IGKTYPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNML 455 + K + K + EH R L+Q+ EE+ L Sbjct: 442 LKVKFQKMKNNISVLQKVLSETDKTKSQSEHQNLQGKKKLCNLRFILQQQEEERIKAEEL 501 Query: 456 YKKNREELERKEKQYKKEVEA-KQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDEN 514 Y+K+ EEL+ E+QY+ + E KQ + T++SLE++ KT R+ N++FH HE + L EN Sbjct: 502 YEKDIEELKIMEEQYRTQTEVKKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQEN 561 Query: 515 CILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRY 574 +++ +IA LR EI T+K+ N E ENKY KDI+I+KE N LEK +K NEE +T+T RY Sbjct: 562 HLMRDEIARLRLEIDTIKHQNQETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITRY 621 Query: 575 QQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLAL 634 +ELN L ENT LN+EL KEK+S RLE ++ESY+ RLAAA+ H + ++R+L+LA Sbjct: 622 SKELNVLMDENTMLNSELQKEKQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAF 681 Query: 635 ERTRD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLAL 692 + T + +Q + +S I + L++QLS+ + + L+ + R++L++K+L + Sbjct: 682 QSTVNEWCHLQEDTNSHI-------QILSQQLSKAESTSSGLETELHYEREALKEKTLHI 734 Query: 693 ETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVH 752 E +Q LS+TQ++ ++++ MYQN + + K VE+ + LQ +N QQ +D Sbjct: 735 EHMQGVLSRTQRRLEDIEHMYQNDQPILEKYVRKQQSVEDGLFQLQSQNLLYQQQCNDAR 794 Query: 753 QKEDHKE-IVTNIQRGFIESGKKDLV----LEEKSKKLMNECDHLKESLFQYEREKTE 805 +K D++E + NIQ ++ +K LEE +K LM EC LKE QYE+EK E Sbjct: 795 KKADNQEKTIINIQVKCEDTVEKLQAECRKLEENNKGLMKECTLLKERQCQYEKEKEE 852 >gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] Length = 1363 Score = 378 bits (971), Expect = e-104 Identities = 270/791 (34%), Positives = 392/791 (49%), Gaps = 142/791 (17%) Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61 KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR DLD Sbjct: 102 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 161 Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121 DK+ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+ Sbjct: 162 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 221 Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181 GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M Sbjct: 222 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 281 Query: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241 VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA Sbjct: 282 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 341 Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301 L IQQQILEHK K+LK + LR D N T Sbjct: 342 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 374 Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361 PE + + K + + + EG A+H Sbjct: 375 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 398 Query: 362 QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421 L VASEE+QER ERSE KQPQ + K E G +R I Sbjct: 399 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 442 Query: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477 + + K QE + T +N ++K N E + +K QY +++ Sbjct: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 500 Query: 478 QLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537 ++K++ AR + H + + L+A++ L + T N+ E Sbjct: 501 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 543 Query: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRL 588 + KD+++V ET + + E++TE + + + N LK + Sbjct: 544 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 601 Query: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648 L ++ + + ++ D++ Q R+ H E ++ + Q Sbjct: 602 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 652 Query: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696 I + + EN L QL + +I N +D ++ L R K L E ++ Sbjct: 653 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 712 Query: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748 L Q +++ E + + + + ++ + K++ E + CH+ + W ++ Sbjct: 713 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 772 Query: 749 DDVHQKEDHKE 759 ++ +E H+E Sbjct: 773 VEIQPEEKHEE 783 Score = 305 bits (780), Expect = 1e-82 Identities = 169/374 (45%), Positives = 257/374 (68%), Gaps = 8/374 (2%) Query: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498 L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N Sbjct: 363 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 419 Query: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558 +D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK Sbjct: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 479 Query: 559 YIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618 ++LNEEMIT+ +Y Q+LN LKAEN RLN++L KEK +K+RLEA++ES S LA AI+ Sbjct: 480 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 539 Query: 619 KHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678 +++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K Sbjct: 540 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 598 Query: 679 RKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738 R+TRD+LR+K+LALE+VQ DL Q Q + +EMK+M+ N EAK + S GK N EERI + Sbjct: 599 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 658 Query: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQ 798 EN L +QL+D ++ D+KEIV NI R +E+GK+DL LEE++K+LMNE ++LKE L Q Sbjct: 659 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 717 Query: 799 YEREKTEGVVSIKE 812 YE+EK E V ++E Sbjct: 718 YEKEKAEREVIVRE 731 >gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] Length = 1366 Score = 378 bits (971), Expect = e-104 Identities = 270/791 (34%), Positives = 392/791 (49%), Gaps = 142/791 (17%) Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61 KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR DLD Sbjct: 131 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 190 Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121 DK+ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+ Sbjct: 191 VRDKKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 250 Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181 GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M Sbjct: 251 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 310 Query: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241 VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA Sbjct: 311 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 370 Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301 L IQQQILEHK K+LK + LR D N T Sbjct: 371 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 403 Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361 PE + + K + + + EG A+H Sbjct: 404 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 427 Query: 362 QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421 L VASEE+QER ERSE KQPQ + K E G +R I Sbjct: 428 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 471 Query: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477 + + K QE + T +N ++K N E + +K QY +++ Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 529 Query: 478 QLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537 ++K++ AR + H + + L+A++ L + T N+ E Sbjct: 530 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 572 Query: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRL 588 + KD+++V ET + + E++TE + + + N LK + Sbjct: 573 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 630 Query: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648 L ++ + + ++ D++ Q R+ H E ++ + Q Sbjct: 631 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 681 Query: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696 I + + EN L QL + +I N +D ++ L R K L E ++ Sbjct: 682 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 741 Query: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748 L Q +++ E + + + + ++ + K++ E + CH+ + W ++ Sbjct: 742 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 801 Query: 749 DDVHQKEDHKE 759 ++ +E H+E Sbjct: 802 VEIQPEEKHEE 812 Score = 305 bits (780), Expect = 1e-82 Identities = 169/374 (45%), Positives = 257/374 (68%), Gaps = 8/374 (2%) Query: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498 L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N Sbjct: 392 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 448 Query: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558 +D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 508 Query: 559 YIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618 ++LNEEMIT+ +Y Q+LN LKAEN RLN++L KEK +K+RLEA++ES S LA AI+ Sbjct: 509 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 568 Query: 619 KHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678 +++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K Sbjct: 569 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 627 Query: 679 RKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738 R+TRD+LR+K+LALE+VQ DL Q Q + +EMK+M+ N EAK + S GK N EERI + Sbjct: 628 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 687 Query: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQ 798 EN L +QL+D ++ D+KEIV NI R +E+GK+DL LEE++K+LMNE ++LKE L Q Sbjct: 688 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 746 Query: 799 YEREKTEGVVSIKE 812 YE+EK E V ++E Sbjct: 747 YEKEKAEREVIVRE 760 >gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] Length = 1139 Score = 377 bits (968), Expect = e-104 Identities = 269/791 (34%), Positives = 392/791 (49%), Gaps = 142/791 (17%) Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61 KL FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVE CL RR DLD Sbjct: 131 KLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLD 190 Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121 D++ RT LHLACA G VQVVTLL++RKCQI++CD+ NRTPL++AVHCQEEACA+ILL+ Sbjct: 191 VRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLK 250 Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181 GANPN+KDIYGNTALHYAVY+E TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M Sbjct: 251 RGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 310 Query: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241 VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA Sbjct: 311 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFC 370 Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301 L IQQQILEHK K+LK + LR D N T Sbjct: 371 CDLRSIQQQILEHKNKMLK-----------------NHLRND----------NQETAAMK 403 Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361 PE + + K + + + EG A+H Sbjct: 404 PENLKK-------RKKRKKLKKRKEGAKAEH----------------------------- 427 Query: 362 QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKI 421 L VASEE+QER ERSE KQPQ + K E G +R I Sbjct: 428 -NLKVASEEKQERLERSENKQPQDSQSYGKKKDEMF---------------GNFMLKRDI 471 Query: 422 GKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKK----NREELERKEKQYKKEVEAK 477 + + K QE + T +N ++K N E + +K QY +++ Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLN-- 529 Query: 478 QLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLE 537 ++K++ AR + H + + L+A++ L + T N+ E Sbjct: 530 ---------DLKAENARLNSKLEKEKHNKER--------LEAEVESLHSNLATAINEYNE 572 Query: 538 KENKYLKDIKIV---------KETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRL 588 + KD+++V ET + + E++TE + + + N LK + Sbjct: 573 ILER--KDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRET 630 Query: 589 NAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSS 648 L ++ + + ++ D++ Q R+ H E ++ + Q Sbjct: 631 RDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKE---------SQSIGKQNSSEE 681 Query: 649 AISKVKDENEFLTEQLSET-------QIKFNALKDKFRKTRDSL---RKKSLALE--TVQ 696 I + + EN L QL + +I N +D ++ L R K L E ++ Sbjct: 682 RIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLK 741 Query: 697 NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERI-----CHLQRENAWLVQQ---L 748 L Q +++ E + + + + ++ + K++ E + CH+ + W ++ Sbjct: 742 EKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQ 801 Query: 749 DDVHQKEDHKE 759 ++ +E H+E Sbjct: 802 VEIQPEEKHEE 812 Score = 305 bits (780), Expect = 1e-82 Identities = 169/374 (45%), Positives = 257/374 (68%), Gaps = 8/374 (2%) Query: 442 LKQENEEKTNV---NMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498 L+ +N+E + N+ +K R++L+++++ K E L+ + + + + + N Sbjct: 392 LRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAE---HNLKVASEEKQERLERSENKQP 448 Query: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558 +D ++ + K M N +LK DIA+L++E+ +KND+L KE KY+++IK + E NA EK Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEK 508 Query: 559 YIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAIS 618 ++LNEEMIT+ +Y Q+LN LKAEN RLN++L KEK +K+RLEA++ES S LA AI+ Sbjct: 509 SVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAIN 568 Query: 619 KHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKF 678 +++E ++ ++L+L L R DVS M S IS++ D+NE LTEQ+ + ++KFN LK K Sbjct: 569 EYNEILE-RKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKL 627 Query: 679 RKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQ 738 R+TRD+LR+K+LALE+VQ DL Q Q + +EMK+M+ N EAK + S GK N EERI + Sbjct: 628 RETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRE 687 Query: 739 RENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQ 798 EN L +QL+D ++ D+KEIV NI R +E+GK+DL LEE++K+LMNE ++LKE L Q Sbjct: 688 LENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDL-LEERNKELMNEYNYLKEKLLQ 746 Query: 799 YEREKTEGVVSIKE 812 YE+EK E V ++E Sbjct: 747 YEKEKAEREVIVRE 760 >gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] Length = 561 Score = 375 bits (964), Expect = e-104 Identities = 239/529 (45%), Positives = 322/529 (60%), Gaps = 46/529 (8%) Query: 265 DVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQ 324 DVG SDESAVSI HEL VDSLP DD+DL+VATKQCVPEKVSEPL G SHEKGNRIVNG+ Sbjct: 54 DVGISDESAVSILHELCVDSLPTLDDEDLSVATKQCVPEKVSEPLRGPSHEKGNRIVNGK 113 Query: 325 GEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQ 384 G+GPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQ LPVA EEEQER ERSEKKQ Q Sbjct: 114 GKGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQTLPVALEEEQERCERSEKKQSQ 173 Query: 385 VKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQ 444 VKEGNNTNKSEKIQLSEN+C STSSAAA RLT+QRK+GKTYPQQFPKKLK+EHD Sbjct: 174 VKEGNNTNKSEKIQLSENVCHSTSSAAADRLTKQRKVGKTYPQQFPKKLKKEHD------ 227 Query: 445 ENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNR--DFH 502 REELERKEKQYKKEVEAKQLEPTVQSL+MK KT RNTPN+ Sbjct: 228 ---------------REELERKEKQYKKEVEAKQLEPTVQSLDMKLKTTRNTPNQINQSL 272 Query: 503 NHEEMKGLMDENCILKADIAILRQEICTMKN--DNLE-KENKYLKDIKIVKETNAALEKY 559 + + K + N D++ +Q+I MK +N E K N V+E L+ Sbjct: 273 RYSQKKVIGFRNS--PNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSCVEERICQLQHE 330 Query: 560 IKLNEEMITETAFR--YQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAI 617 E+ + + + +++ + ++ + L +E K+L + + + L Sbjct: 331 NPCIEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNECDHLKESLFQYE 390 Query: 618 SKHSESVKTERNLKL----ALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFN- 672 + +E V R L+ +L++ + +E S DE + ++L + + +F+ Sbjct: 391 REKAERVVVVRQLQQEAADSLKKLTMLESPLEGISHYHINLDETQVPKKKLFQVESQFDD 450 Query: 673 ------ALKDK---FRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNS 723 A+ K K +++ L+++ VQ + + ++ + ++E N + + NS Sbjct: 451 FMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENS 510 Query: 724 TGKWNCVEERICHLQRENAWLVQQLDDVHQKE--DHKEIVTNIQRGFIE 770 + + ++E L V++L+++H +E +HK+ + + + I+ Sbjct: 511 MVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQLEQLNKDIIQ 559 Score = 212 bits (540), Expect = 1e-54 Identities = 129/263 (49%), Positives = 160/263 (60%), Gaps = 19/263 (7%) Query: 562 LNEEMITETAFRYQQELNYLKAENTRLNAELLKE-----KESKKRLEADI-ESYQSRLAA 615 L E A +QE + E + +KE K K +L ++ S S A Sbjct: 147 LRAEQTLPVALEEEQE----RCERSEKKQSQVKEGNNTNKSEKIQLSENVCHSTSSAAAD 202 Query: 616 AISKHSESVKT---ERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFN 672 ++K + KT + KL E R+ ++E K + E + L + +K Sbjct: 203 RLTKQRKVGKTYPQQFPKKLKKEHDRE---ELERKEKQYKKEVEAKQLEPTVQSLDMKLK 259 Query: 673 ALKDKFRKTRDSLR---KKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNC 729 ++ + SLR KK + NDLSQTQQQ +EMKEMY+NAEAKVNNSTGKW+C Sbjct: 260 TTRNTPNQINQSLRYSQKKVIGFRNSPNDLSQTQQQIKEMKEMYENAEAKVNNSTGKWSC 319 Query: 730 VEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNEC 789 VEERIC LQ EN + QQLDDVHQKEDHKEIVTNIQRGFIESGKKDL+LEEK+KKLMNEC Sbjct: 320 VEERICQLQHENPCIEQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLMLEEKNKKLMNEC 379 Query: 790 DHLKESLFQYEREKTEGVVSIKE 812 DHLKESLFQYEREK E VV +++ Sbjct: 380 DHLKESLFQYEREKAERVVVVRQ 402 >gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] Length = 1415 Score = 369 bits (948), Expect = e-102 Identities = 289/910 (31%), Positives = 439/910 (48%), Gaps = 132/910 (14%) Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61 KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD Sbjct: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169 Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121 A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE Sbjct: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229 Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181 GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M Sbjct: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289 Query: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241 VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+ Sbjct: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349 Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301 L I+QQILEHK K+LK + LR D+ + K N+ K+ Sbjct: 350 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 391 Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361 K L +S EK R+ + + P K +D + +K++ L+ E Sbjct: 392 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 447 Query: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 A+ S +++++ + K ++ N N + ++L+E + T R +QQ Sbjct: 448 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 499 Query: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENEE-KTNVNMLYKKNREELERKE----------- 467 K + +L KE+H++ L+ E E +++ + E +ERK+ Sbjct: 500 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 559 Query: 468 -KQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCI----LKADIA 522 + K QL + L + AR N E + + E + ++ D+ Sbjct: 560 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLR 619 Query: 523 ILRQEICTMK----------NDNLEKENKYLKDIKIVKETNAALE------------KYI 560 + I MK + ++ K+N + I+ + N LE K I Sbjct: 620 QAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEI 679 Query: 561 KLN----------EEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQ 610 +N E+++ E +E NYLK +LL+ ++ K E + +Q Sbjct: 680 VINIHRDCLENGKEDLLEERNKELMKEYNYLK-------EKLLQCEKEKAEREVIVREFQ 732 Query: 611 SRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIK 670 L + +KT + LE T + + + K + E E+ E K Sbjct: 733 EELV-------DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785 Query: 671 FNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------- 717 L T D +RKK+ LE + + T M + N + Sbjct: 786 LFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLK 845 Query: 718 ---------AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQ 753 K N+ + V +L ++N L Q+L D Sbjct: 846 MDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKML 905 Query: 754 KEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKED 813 +E+ + T++++ +E GK E ++ + E + L+E Q + E + + + +D Sbjct: 906 EEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKD 965 Query: 814 KYFQTSRKTI 823 +K + Sbjct: 966 NTASLKKKEL 975 Score = 32.3 bits (72), Expect = 1.8 Identities = 50/238 (21%), Positives = 97/238 (40%), Gaps = 46/238 (19%) Query: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482 KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE Sbjct: 851 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 908 Query: 483 VQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542 V +L KT + +E K +DE + QEI ++ +L+K+ +Y Sbjct: 909 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 955 Query: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRL 602 K ++ + + N A K ++EL E + K K + + + Sbjct: 956 EKQLEQLNKDNTASLK----------------KKELTLKDVE-----CKFSKMKTAYEEV 994 Query: 603 EADIESYQSRLAAAISKHSESVK--TERNLKLALERTRDVSVQVEMSSAISKVKDENE 658 ++E ++ A A+ ++ K + + K+A+ T+ + + M +S + E Sbjct: 995 TTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPE 1052 >gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] Length = 1002 Score = 369 bits (948), Expect = e-102 Identities = 289/910 (31%), Positives = 439/910 (48%), Gaps = 132/910 (14%) Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61 KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD Sbjct: 3 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 62 Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121 A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE Sbjct: 63 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 122 Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181 GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M Sbjct: 123 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 182 Query: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241 VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+ Sbjct: 183 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 242 Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301 L I+QQILEHK K+LK + LR D+ + K N+ K+ Sbjct: 243 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 284 Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361 K L +S EK R+ + + P K +D + +K++ L+ E Sbjct: 285 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 340 Query: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 A+ S +++++ + K ++ N N + ++L+E + T R +QQ Sbjct: 341 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 392 Query: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENEE-KTNVNMLYKKNREELERKE----------- 467 K + +L KE+H++ L+ E E +++ + E +ERK+ Sbjct: 393 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 452 Query: 468 -KQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCI----LKADIA 522 + K QL + L + AR N E + + E + ++ D+ Sbjct: 453 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLR 512 Query: 523 ILRQEICTMK----------NDNLEKENKYLKDIKIVKETNAALE------------KYI 560 + I MK + ++ K+N + I+ + N LE K I Sbjct: 513 QAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEI 572 Query: 561 KLN----------EEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQ 610 +N E+++ E +E NYLK +LL+ ++ K E + +Q Sbjct: 573 VINIHRDCLENGKEDLLEERNKELMKEYNYLK-------EKLLQCEKEKAEREVIVREFQ 625 Query: 611 SRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIK 670 L + +KT + LE T + + + K + E E+ E K Sbjct: 626 EELV-------DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 678 Query: 671 FNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------- 717 L T D +RKK+ LE + + T M + N + Sbjct: 679 LFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLK 738 Query: 718 ---------AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQ 753 K N+ + V +L ++N L Q+L D Sbjct: 739 MDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKML 798 Query: 754 KEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKED 813 +E+ + T++++ +E GK E ++ + E + L+E Q + E + + + +D Sbjct: 799 EEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKD 858 Query: 814 KYFQTSRKTI 823 +K + Sbjct: 859 NTASLKKKEL 868 >gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] Length = 1415 Score = 369 bits (948), Expect = e-102 Identities = 289/910 (31%), Positives = 439/910 (48%), Gaps = 132/910 (14%) Query: 2 KLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLD 61 KLF FG R GQ S+D Y G GY IRD EL+KIHRAA+KGDAAEVERCL RR DLD Sbjct: 110 KLFSFGRRLGQALLSSMDQEYAGPGYDIRDWELRKIHRAAIKGDAAEVERCLTRRFRDLD 169 Query: 62 ALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLE 121 A D++ RT LHLACA G VQVVTLL++R+CQID+CD+ NRTPL++AVH QEEACA++LLE Sbjct: 170 ARDRKDRTVLHLACAHGRVQVVTLLLHRRCQIDICDRLNRTPLMKAVHSQEEACAIVLLE 229 Query: 122 HGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKM 181 GANPN++DIYGNTALHYAVY++ TSLAE+LLSH A+IEAL+K+ NTPLLFAI +++ M Sbjct: 230 CGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHM 289 Query: 182 VEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAIS 241 VEFLLK +A+ HAVD +R+AL+LAV ++ IV +LL+QNI + +QDM G+ AEDYA+ Sbjct: 290 VEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIRISSQDMFGQTAEDYALC 349 Query: 242 HHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCV 301 L I+QQILEHK K+LK + LR D+ + K N+ K+ Sbjct: 350 SDLRSIRQQILEHKNKMLK-----------------NHLRNDNQETAAMKPANL-KKRKE 391 Query: 302 PEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAE 361 K L +S EK R+ + + P K +D + +K++ L+ E Sbjct: 392 RAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKK----KDAMYGNFMLKKDIAMLKEE 447 Query: 362 -QALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRK 420 A+ S +++++ + K ++ N N + ++L+E + T R +QQ Sbjct: 448 LYAIKNDSLRKEKKYIQEIKSITEI----NANFEKSVRLNEKMITKT----VARYSQQLN 499 Query: 421 IGKTYPQQFPKKL-KEEHDRCTLKQENEE-KTNVNMLYKKNREELERKE----------- 467 K + +L KE+H++ L+ E E +++ + E +ERK+ Sbjct: 500 DLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAINEYNEIVERKDLELVLWRADDV 559 Query: 468 -KQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCI----LKADIA 522 + K QL + L + AR N E + + E + ++ D+ Sbjct: 560 SRHEKMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALGSVQLDLR 619 Query: 523 ILRQEICTMK----------NDNLEKENKYLKDIKIVKETNAALE------------KYI 560 + I MK + ++ K+N + I+ + N LE K I Sbjct: 620 QAQHRIKEMKQMHPNGEAKESQSIGKQNSLEERIRQQELENLLLERQLEDARKEGDNKEI 679 Query: 561 KLN----------EEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQ 610 +N E+++ E +E NYLK +LL+ ++ K E + +Q Sbjct: 680 VINIHRDCLENGKEDLLEERNKELMKEYNYLK-------EKLLQCEKEKAEREVIVREFQ 732 Query: 611 SRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIK 670 L + +KT + LE T + + + K + E E+ E K Sbjct: 733 EELV-------DHLKTFSISESPLEGTSHCHINLNETWTSKKKLFQVEIQPEEKHEEFRK 785 Query: 671 FNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------------- 717 L T D +RKK+ LE + + T M + N + Sbjct: 786 LFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLK 845 Query: 718 ---------AKVNNSTGKWNCVEERICHLQRENAWLVQQL---------------DDVHQ 753 K N+ + V +L ++N L Q+L D Sbjct: 846 MDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKML 905 Query: 754 KEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKED 813 +E+ + T++++ +E GK E ++ + E + L+E Q + E + + + +D Sbjct: 906 EEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEKQLEQLNKD 965 Query: 814 KYFQTSRKTI 823 +K + Sbjct: 966 NTASLKKKEL 975 Score = 32.3 bits (72), Expect = 1.8 Identities = 50/238 (21%), Positives = 97/238 (40%), Gaps = 46/238 (19%) Query: 431 KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK--------EKQYKKEVEAKQLEPT 482 KKLK++ + ++E VN+ K+ E L ++ EK K E + K LE Sbjct: 851 KKLKQKFNDLVAEKEAVSSECVNLA--KDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEE 908 Query: 483 VQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKY 542 V +L KT + +E K +DE + QEI ++ +L+K+ +Y Sbjct: 909 VLNL----KTHMEKDMVELGKLQEYKSELDERAV---------QEIEKLEEIHLQKQAEY 955 Query: 543 LKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRL 602 K ++ + + N A K ++EL E + K K + + + Sbjct: 956 EKQLEQLNKDNTASLK----------------KKELTLKDVE-----CKFSKMKTAYEEV 994 Query: 603 EADIESYQSRLAAAISKHSESVK--TERNLKLALERTRDVSVQVEMSSAISKVKDENE 658 ++E ++ A A+ ++ K + + K+A+ T+ + + M +S + E Sbjct: 995 TTELEEFKEAFAGAVKANNSMSKKLMKSDKKIAVISTKLFTEKQRMKYFLSTLPTRPE 1052 >gi|154354990 ankyrin repeat domain 26 [Homo sapiens] Length = 1710 Score = 328 bits (840), Expect = 2e-89 Identities = 195/444 (43%), Positives = 275/444 (61%), Gaps = 62/444 (13%) Query: 431 KKLKEEHDRCTLK----QENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQ-LEPTVQS 485 +K++ E + C+L+ QE E++ N + LY+K RE+L RKE+QY+KEVE KQ LE ++Q+ Sbjct: 780 QKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQLELSLQT 839 Query: 486 LEMKSKTARNTPNR---------------------------------------------- 499 LEM+ +T ++ N+ Sbjct: 840 LEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQKKMNSE 899 Query: 500 DFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKY 559 + H+HEE K L +N +L+ +IA+LR EI T+KN N EKE K +D+KIVKE N L+K Sbjct: 900 NSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKT 959 Query: 560 IKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISK 619 IK NEE +T+T +Y L+ L AEN LN++L EK+SK+RLEA++ESY SRLAAAI Sbjct: 960 IKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHD 1019 Query: 620 HSESVKTERNLKLALERTRD--VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDK 677 +S ++R L+LA +R RD +Q +M+ +S +KD NE L++QL +T+ K N+L+ + Sbjct: 1020 RDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIE 1079 Query: 678 FRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHL 737 F TRD+LR+K+L LE VQ DLSQTQ Q +EM++ YQN + KVN GK VEER+ L Sbjct: 1080 FHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQL 1139 Query: 738 QRENAWLVQQLDDVHQKEDHKE-IVTNIQRGF--------IESGKKDLVLEEKSKKLMNE 788 Q EN L QQLDD H K D+KE V NIQ F ES K+ L+LEE++K+L++E Sbjct: 1140 QSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISE 1199 Query: 789 CDHLKESLFQYEREKTEGVVSIKE 812 C+HLKE +QYE EK E V +++ Sbjct: 1200 CNHLKERQYQYENEKAEREVVVRQ 1223 Score = 230 bits (586), Expect = 5e-60 Identities = 130/308 (42%), Positives = 183/308 (59%), Gaps = 44/308 (14%) Query: 11 GQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTA 70 G+ +G+ Y+ GY +RD +L KIH+AA G+ A+V++ L R L+ DK +RTA Sbjct: 28 GEPGEGA----YSQPGYHVRDRDLGKIHKAASAGNVAKVQQILLLRKNGLNDRDKMNRTA 83 Query: 71 LHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKD 130 LHLACA+GH +VVTLLV+RKCQ++VCD ENRT L++AV CQEE CA ILLEHGA+PNL D Sbjct: 84 LHLACANGHPEVVTLLVDRKCQLNVCDNENRTALMKAVQCQEEKCATILLEHGADPNLAD 143 Query: 131 IYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKA 190 ++GNTALHYAVY+E S+A KLL + A+IEA +KD+ TPLL A+ KK++MVEFL+K+KA Sbjct: 144 VHGNTALHYAVYNEDISVATKLLLYDANIEAKNKDDLTPLLLAVSGKKQQMVEFLIKKKA 203 Query: 191 SSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQ 250 + +AVD+L S +++ Y ++ I H ++ Sbjct: 204 NVNAVDKLESSHQLISEY---------------------------KEERIPKHSSQNSNS 236 Query: 251 ILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLP 310 + E + L + G DS P SDD+DLN TK +++ + Sbjct: 237 VDESSEDSLSRLSGKPGVD-------------DSWPTSDDEDLNFDTKNVPKPSLAKLMT 283 Query: 311 GSSHEKGN 318 S + N Sbjct: 284 ASQQSRKN 291 Score = 107 bits (266), Expect = 6e-23 Identities = 152/666 (22%), Positives = 280/666 (42%), Gaps = 111/666 (16%) Query: 262 EKSDVGS--SDESAVSIFHELRVDSLP-ASDDKDLNVATKQCVPE-KVSEPLPGSSHEKG 317 ++ D+ S ES F + VD L A+D K+ N+ +Q + + GS + K Sbjct: 412 QEEDIESPWDSESISENFPQKYVDPLAGAADGKEKNIGNEQAEDVFYIPSCMSGSRNFKM 471 Query: 318 NRIVNGQGEGPPAKHPS-------LKPSTEVEDPAVKGAVQRKNVQTLRA-EQALPVASE 369 ++ + + G P H LKP+ E++D A K+VQT +A E L VASE Sbjct: 472 AKLEDTRNVGMPVAHMESPERYLHLKPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASE 531 Query: 370 EEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAA-----GRLTQQRKIGKT 424 EEQER E SE QPQV+E +++ ++++S NI D + A L Q+RK G+T Sbjct: 532 EEQER-EGSENNQPQVEEERKKHRNNEMEVSANIHDGATDDAEDDDDDDGLIQKRKSGET 590 Query: 425 YPQQFPKKLKEEHD-----------RCTLKQENEEKTNVNM-LYKK-------------- 458 QQFP+K +E+ + T K++ K +VN ++ K Sbjct: 591 DHQQFPRKENKEYASSGPALQMKEVKSTEKEKRTSKESVNSPVFGKASLLTGGLLQVDDD 650 Query: 459 -NREELERKEKQYKKEV--EAKQLEPTVQSLE------MKSKTAR---NTPNRDFHNHE- 505 + E++ E + K+ E +++ +QS++ S+TA P+ + N Sbjct: 651 SSLSEIDEDEGRPTKKTSNEKNKVKNQIQSMDDVDDLTQSSETASEDCELPHSSYKNFML 710 Query: 506 --EMKGL--MDENCILK-ADIAILRQEICTMKNDNLE-----------KENKYLKDIKIV 549 E G+ D +LK D A+ + + +K ++ E K N +++ Sbjct: 711 LIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVKIKKMEDKVNVLQRELSET 770 Query: 550 KETNAALEKYIKLNEEMITETAFRYQQE----------LNYLKAENTRLNAELLKEKESK 599 KE + LE E + F QE ++ + R + KE E K Sbjct: 771 KEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVK 830 Query: 600 KRLEADIESYQSRLAAAISKHSESVKTERNLKLALER------------TRDVSVQVEMS 647 ++LE +++ + L S ++ V+ + + L R T +S Q E+ Sbjct: 831 QQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIE 890 Query: 648 SAISKVKDENEFLTEQLSETQIKFNALKDKFRKTR---DSLRKKSLALE-TVQNDLSQTQ 703 A K+ EN E+ + K + L+++ R D+++ ++ E DL + Sbjct: 891 MAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVK 950 Query: 704 QQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTN 763 ++ +++++ + E + + ++N R+ L ENA L +L++ Q ++ E Sbjct: 951 EKNEDLQKTIKQNEETLTQTISQYN---GRLSVLTAENAMLNSKLENEKQSKERLEAEVE 1007 Query: 764 IQRGFIESGKKDLVLEEKSKKLM--------NECDHLKESLFQYEREKTEGVVSIKEDKY 815 + + D E SK+ + +EC L++ + ++ + I + Sbjct: 1008 SYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKM-NFDVSNLKDNNEILSQQL 1066 Query: 816 FQTSRK 821 F+T K Sbjct: 1067 FKTESK 1072 Score = 49.3 bits (116), Expect = 1e-05 Identities = 100/480 (20%), Positives = 192/480 (40%), Gaps = 47/480 (9%) Query: 350 VQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSS 409 VQ+ QT + + + EQ + + KQ V+E + +SE + L + + D+ + Sbjct: 1097 VQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNK 1156 Query: 410 AAAGRLTQQRKIGKTYPQQFP---KKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERK 466 A + K QF +KL+ E ++ +L E K ++ + + + Sbjct: 1157 A-----DNKEKTVINIQDQFHAIVQKLQAESEKQSLLLEERNKELISECNHLKERQYQYE 1211 Query: 467 EKQYKKEVEAKQLE----PTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDE-----NCIL 517 ++ ++EV +QL+ T++ M + T + +E + L + N + Sbjct: 1212 NEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQDLKKKLGQIRNQLQ 1271 Query: 518 KADIAILRQEICTMK----NDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFR 573 +A C K LEK+N LK + + K+ + E L ++E Sbjct: 1272 EAQDRHTEAVRCAEKMQDHKQKLEKDNAKLK-VTVKKQMDKIEELQKNLLNANLSEDE-- 1328 Query: 574 YQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLA 633 +++L L L L +E + LE +I +++ L K +E E + Sbjct: 1329 -KEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGD 1387 Query: 634 LERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALE 693 L+ + Q EM I+K+K + + LT +L K L K L+++ L+++ Sbjct: 1388 LKTS-----QFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTK----NQILQEELLSMK 1438 Query: 694 TVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCV-------EERICH-----LQREN 741 TVQ + Q+ +++++ N + + + + V EER L+ N Sbjct: 1439 TVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVN 1498 Query: 742 AWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYER 801 +L Q E +E + +E KDL E SK ++ D K L +Y++ Sbjct: 1499 LFLQAQAASQENLEQFRENNFASMKSQMELRIKDLE-SELSKIKTSQEDFNKTELEKYKQ 1557 Score = 43.9 bits (102), Expect = 6e-04 Identities = 78/432 (18%), Positives = 172/432 (39%), Gaps = 72/432 (16%) Query: 439 RCTLKQENEEKTNVNMLYKK---NREELERKEKQYKKE--VEAKQLEPTVQSLEMKSKTA 493 +C +K+ ++ N + K +E +E + Q + E + +QL+ + K KT Sbjct: 1105 QCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTV 1164 Query: 494 RNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETN 553 N ++ ++++ ++ +L + +N L E +LK+ + E Sbjct: 1165 INIQDQFHAIVQKLQAESEKQSLLLEE-----------RNKELISECNHLKERQYQYENE 1213 Query: 554 AALEKYI--KLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQS 611 A + + +L +E+ + E + R+N E + + L+ + ++ Sbjct: 1214 KAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLE-----DETQDLKKKLGQIRN 1268 Query: 612 RLAAAISKHSESVKTERNL---KLALERTRDVSVQVEMSSAISKVKDE-----NEFLTEQ 663 +L A +H+E+V+ + K LE+ + ++V + + K+++ N L+E Sbjct: 1269 QLQEAQDRHTEAVRCAEKMQDHKQKLEKD-NAKLKVTVKKQMDKIEELQKNLLNANLSED 1327 Query: 664 LSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE------ 717 E K LK D KK++ LE + T++ Y+N E Sbjct: 1328 EKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGD 1387 Query: 718 ----------------AKVNNSTGKWNCVEERICHLQRENAWLVQQLDDV---------- 751 K+++ T + + HL +N L ++L + Sbjct: 1388 LKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEKL 1447 Query: 752 --HQKEDHKEIV---TNIQRGFIESGKKDLVLEEKSKKLMNE-CDHLKE-SLF-QYEREK 803 ++K+ +E++ ++I+R +E G+ +E ++ E + LKE +LF Q + Sbjct: 1448 QKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQEIAEKLKEVNLFLQAQAAS 1507 Query: 804 TEGVVSIKEDKY 815 E + +E+ + Sbjct: 1508 QENLEQFRENNF 1519 >gi|115495445 ankyrin repeat domain 30A [Homo sapiens] Length = 1341 Score = 284 bits (727), Expect = 2e-76 Identities = 186/525 (35%), Positives = 289/525 (55%), Gaps = 51/525 (9%) Query: 328 PPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHE---------RS 378 PP K + +P+ E++ A++ KN QTLRA+Q P SE +Q++ E R Sbjct: 817 PPEKPSAFEPAIEMQKSVPNKALELKNEQTLRADQMFP--SESKQKKVEENSWDSESLRE 874 Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAA----------------------AGRLT 416 Q V T++ E ++S + DSTS + G++ Sbjct: 875 TVSQKDVCVPKATHQKEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTGKME 934 Query: 417 QQRKI----------GKTYPQQFP-KKLKEEHDRC----TLKQENEEKTNVNMLYKKNRE 461 Q +K K Q +K+K E + C TL QE E++ N ++L +K RE Sbjct: 935 QMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEKIRE 994 Query: 462 ELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKAD 520 EL R E+Q++KE+E KQ LE ++ +++ K+ + N+ H HE L+ ENC+LK + Sbjct: 995 ELGRIEEQHRKELEVKQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCMLKKE 1054 Query: 521 IAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNY 580 IA+L+ EI T+K+ EKENKY +DIKI+KE NA L+ +KL EE +T+ A +Y +L Sbjct: 1055 IAMLKLEIATLKHQYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKV 1114 Query: 581 LKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDV 640 L AENT L ++L KEK+ K+ LEA+IES+ RLA+A+ H + V + ++ + A D Sbjct: 1115 LIAENTMLTSKL-KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDA 1173 Query: 641 SVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLS 700 +Q +M+ +S NE L + LSE Q K +LK D+LR+ +L E Q D Sbjct: 1174 CLQRKMNVDVSSTIYNNEVLHQPLSEAQRKSKSLKINLNYAGDALRENTLVSEHAQRDQR 1233 Query: 701 QTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEI 760 +TQ Q +E + MYQN + VN T + +++++ LQ +N WL QQL H+K D+K Sbjct: 1234 ETQCQMKEAEHMYQNEQDNVNKHTEQQESLDQKLFQLQSKNMWLQQQLVHAHKKADNKSK 1293 Query: 761 VTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTE 805 +T I F+E + +L+EK++++ N +HLK ++QYE+EK E Sbjct: 1294 IT-IDIHFLERKMQHHLLKEKNEEIFNYNNHLKNRIYQYEKEKAE 1337 Score = 225 bits (574), Expect = 1e-58 Identities = 167/499 (33%), Positives = 256/499 (51%), Gaps = 63/499 (12%) Query: 55 RRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEA 114 +++ +L+ D Q RTALH AC +GH +VVT LV+RKCQ+DV D E+RTPL++A+ C +EA Sbjct: 5 KKTINLNIQDAQKRTALHWACVNGHEEVVTFLVDRKCQLDVLDGEHRTPLMKALQCHQEA 64 Query: 115 CAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAI 174 CA IL++ GA+ NL D+YGNTALHYAVYSE S+ KLLSHGA IE +K + TPLL +I Sbjct: 65 CANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSHGAVIEVHNKASLTPLLLSI 124 Query: 175 ICKKEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRD 234 + E++VEFLL + A+++AV++ + +ALMLAV + S IV +LL+QN+DVFA D+CG Sbjct: 125 TKRSEQIVEFLLIKNANANAVNKYKCTALMLAVCHGSSEIVGMLLQQNVDVFAADICGVT 184 Query: 235 AEDYAISHHLTKIQQQILEHKKKILKK------EKSDVGSSDE----------SAVSIFH 278 AE YA++ I +QI+E+ +K+ K E + G+ DE +A S+ Sbjct: 185 AEHYAVTCGFHHIHEQIMEYIRKLSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVE 244 Query: 279 ELRVDSLPASD-DKDLNVATKQCVPEKVSEPLPGSSHE-------KGNRIVNGQGEGP-- 328 + ++ P + D + + P++ + + G+S + + E P Sbjct: 245 KTPDEAAPLVERTPDTAESLVEKTPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPRE 304 Query: 329 ---PAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASE------EEQERHERSE 379 PAK S K + + K A ++K SE + + R E Sbjct: 305 ITSPAKETSEKFTWPAKGRPRKIAWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWE 364 Query: 380 KKQPQVKEG-------NNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKK 432 KK+ VK G N T EK + C + S+ QR FP + Sbjct: 365 KKETPVKTGCVARVTSNKTKVLEKGRSKMIACPTKESSTKASANDQR---------FPSE 415 Query: 433 LKEEHDR---CTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTV--QSLE 487 K+E D C + E + + E + +K + +EVE +P+ ++E Sbjct: 416 SKQEEDEEYSCDSRSLFESSAKIQVCIP---ESIYQKVMEINREVEEPPKKPSAFKPAIE 472 Query: 488 MKSKTARNTPNRDFHNHEE 506 M++ + PN+ F E Sbjct: 473 MQN----SVPNKAFELKNE 487 Score = 55.1 bits (131), Expect = 3e-07 Identities = 122/602 (20%), Positives = 234/602 (38%), Gaps = 76/602 (12%) Query: 250 QILEHKKKILKKEKSDV---GSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE--- 303 ++ +K K+L+K +S + + + S + ++ R S ++ + + + E Sbjct: 377 RVTSNKTKVLEKGRSKMIACPTKESSTKASANDQRFPSESKQEEDEEYSCDSRSLFESSA 436 Query: 304 KVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQA 363 K+ +P S ++K I N + E PP K + KP+ E+++ A + KN QTLRA+ Sbjct: 437 KIQVCIPESIYQKVMEI-NREVEEPPKKPSAFKPAIEMQNSVPNKAFELKNEQTLRADPM 495 Query: 364 LPVASEEE--QERHERSEK-----KQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLT 416 P S+++ +E SE Q V T++ E +++ + +S + + T Sbjct: 496 FPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPNKDGLLKAT 555 Query: 417 QQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLYKKNREEL 463 K+ P K E D T K E K + L KN + L Sbjct: 556 CGMKV------SIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTL 609 Query: 464 --------ERKEKQYKKEV-EAKQLEPTVQSLEMKSKTARNTPNRDFHNHE-----EMKG 509 E K+K Y++ + + L TV ++ A + D N + G Sbjct: 610 RADEILPSESKQKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDG 669 Query: 510 LMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569 L+ NC +K I E+ M+ E K ++ + K ++L E Sbjct: 670 LLKANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALELKNEQTLR 729 Query: 570 TAFRYQQELNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERN 629 E E + ++E L E S+K + ++Q + K ES + Sbjct: 730 ADEILPSESKQKDYEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDNDGF 789 Query: 630 LKLALERTRDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKS 689 LK ++V + + ++ D F E + A+ + + S+ K+ Sbjct: 790 LKAPCR------MKVSIPTKALELMDMQTFKAEPPEKPSAFEPAI-----EMQKSVPNKA 838 Query: 690 LALETVQ----NDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVE--------ERICHL 737 L L+ Q + + ++ + ++++E ++E+ + K CV ++I Sbjct: 839 LELKNEQTLRADQMFPSESKQKKVEENSWDSESLRETVSQKDVCVPKATHQKEMDKISGK 898 Query: 738 QRENAWLVQQLDDVHQKEDHKEIVTN---IQRGFIESGKKDLVLEEKSKKLMNECDHLKE 794 ++ L + LD VH E +E+ + + G +E KK + KK ++E +K Sbjct: 899 LEDSTSLSKILDTVHSCERARELQKDHCEQRTGKMEQMKKKFCV---LKKKLSEAKEIKS 955 Query: 795 SL 796 L Sbjct: 956 QL 957 >gi|222537750 ankyrin repeat domain 30B [Homo sapiens] Length = 1392 Score = 274 bits (700), Expect = 3e-73 Identities = 182/544 (33%), Positives = 297/544 (54%), Gaps = 30/544 (5%) Query: 283 DSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVE 342 D+ SD + ++V+ Q E LP ++++K + NG+ E P K +P+TE++ Sbjct: 869 DTKSTSDSEIISVSDTQNY-----ECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQ 923 Query: 343 DPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSEN 402 + ++ KN QTLRA+ + ER ++K+ N + K++ ++N Sbjct: 924 NSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGR----ELKKDNCEQITAKMEQTKN 979 Query: 403 ICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRC----TLKQENEEKTNVNMLYKK 458 L++ ++I Q K K E + C TL QE E++ NV++L +K Sbjct: 980 ----KFCVLQKELSEAKEIKSQLENQ---KAKWEQELCSVRLTLNQEEEKRRNVDILKEK 1032 Query: 459 NREELERKEKQYKKEVEAKQ-LEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCIL 517 R E +Q +K++E KQ LE T++ +++ K+ + N+ H HE L ENC+L Sbjct: 1033 IRPE-----EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCML 1087 Query: 518 KADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQE 577 K +IA+L+ E+ T+K+ + KENKY +DIKI++E NA L+ +KL ++ +T+ A +Y+++ Sbjct: 1088 KKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQ 1147 Query: 578 LNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERT 637 L L AENT L ++L KEK+ K+ LE +IES+ RLA+A+ H +SV + +N +LA Sbjct: 1148 LKVLTAENTMLTSKL-KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSA 1206 Query: 638 RDVSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQN 697 D +Q M+ +S NE L + L E Q K + K D LR+ +L E Q Sbjct: 1207 GDAPLQGIMNVDVSNTIYNNEVLHQPLYEAQRKSKSPKINLNYAGDDLRENALVSEHAQR 1266 Query: 698 DLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDH 757 D +TQ Q ++ + MYQN + V+ T + +E+++ L+ +N WL QQL H+K + Sbjct: 1267 DRCETQCQMKKAEHMYQNEQDNVDKHTEQQESLEQKLFQLESKNRWLRQQLVYAHKKVNK 1326 Query: 758 KEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQ 817 ++ NIQ K L EK++++ N +HLKE + QYE+EK E VSIK+ KYF Sbjct: 1327 SKVTINIQ---FPEMKMQRHLNEKNEEVFNYGNHLKERIDQYEKEKAEREVSIKKYKYFS 1383 Query: 818 TSRK 821 K Sbjct: 1384 NFLK 1387 Score = 224 bits (571), Expect = 3e-58 Identities = 182/547 (33%), Positives = 277/547 (50%), Gaps = 63/547 (11%) Query: 5 GFGSRRGQTAQGSIDHVYTGSGY-RIRDSELQKIHRAAVKGDAAEVERC-LARRSGDLDA 62 G G R + + VYT Y I +L KIH AA +G ++E+ + ++ +L+ Sbjct: 9 GKGVRGPEPPNPFSERVYTEKDYGTIYFGDLGKIHTAASRGQVQKLEKMTVGKKPVNLNK 68 Query: 63 LDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEH 122 D + RTALH AC +GH +VVT LV+RKCQ++V D E RTPL++A+ C+ EACA IL++ Sbjct: 69 RDMKKRTALHWACVNGHAEVVTFLVDRKCQLNVLDGEGRTPLMKALQCEREACANILIDA 128 Query: 123 GANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMV 182 GA+ N D+YGNTALHYAVYSE+ + LLS+GA IE +K + TPLL AI + ++ V Sbjct: 129 GADLNYVDVYGNTALHYAVYSENLLMVATLLSYGAVIEVQNKASLTPLLLAIQKRSKQTV 188 Query: 183 EFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISH 242 EFLL + A+++A + + +ALMLA+ S IV +LL+QN+DVFA+D+ G AE YA + Sbjct: 189 EFLLTKNANANAFNESKCTALMLAICEGSSEIVGMLLQQNVDVFAEDIHGITAERYAAAC 248 Query: 243 HLTKIQQQILEHKKKILKK------EKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVA 296 + I QQ+LEH +K+ K E + G+ DE+A E D+ + +K + A Sbjct: 249 GVNYIHQQLLEHIRKLPKNPQNTNPEGTSTGTPDEAAP--LAERTPDTAESLLEKTPDEA 306 Query: 297 TK---------QCVPEKVSEPLPGSSHEKGNRIVNGQGEGP-----PAKHPSLKPSTEVE 342 + QC+ + S S+ E +I+ E PAK S K + E + Sbjct: 307 ARLVEGTSAKIQCLGKATSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEK 366 Query: 343 DPAVK----GAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKE------GNNT- 391 + +VK V + L + +A ++ + S E G T Sbjct: 367 ETSVKTECVAGVTPNKTEVLEKGTSNMIACPTKETSTKASTNVDVSSVEPIFSLFGTRTI 426 Query: 392 --NKSEKIQLSENICDSTSSAAAGR-------LTQQRKI----GKTYPQQFPKKLKEEHD 438 ++ K++ N+ S +A + T Q+ I K Q FP + K E D Sbjct: 427 ENSQCTKVEEDFNLATKIISKSAAQNYTCLPDATYQKDIKTINHKIEDQMFPSESKREED 486 Query: 439 R-----CTLKQENEEKTNV---NMLYKK----NR--EELERKEKQYKKEVEAKQLEPTVQ 484 E+ KT V +Y+K NR EEL K +K VE ++ P + Sbjct: 487 EEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVEMQKTVPN-K 545 Query: 485 SLEMKSK 491 + E+K++ Sbjct: 546 AFELKNE 552 Score = 58.5 bits (140), Expect = 2e-08 Identities = 97/464 (20%), Positives = 178/464 (38%), Gaps = 55/464 (11%) Query: 309 LPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVAS 368 LP ++H+K ++G+ E P K LKP+ ++ A++ K+ +T +AE V S Sbjct: 744 LPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMKISLPNKALELKDRETFKAEDVSSVES 803 Query: 369 EEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIG--KTYP 426 +E Q S K++ N+ + Q+R IG + P Sbjct: 804 TFSLFGKPTTENSQ-----------STKVEEDFNLTTKEGATKTVTGQQERDIGIIERAP 852 Query: 427 QQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELE-RKEKQYKKEVEAKQLEPTVQS 485 Q K+ K++ + ++ ++ + + E E Y+KE+ K ++ Sbjct: 853 QDQTNKMPT--SELGRKEDTKSTSDSEIISVSDTQNYECLPEATYQKEI--KTTNGKIE- 907 Query: 486 LEMKSKTARNTPNRDFHNHEEMKGLMDEN-CILKADIAILRQEICTMKNDNLEKENKYLK 544 E K + P + N KGL +N L+AD L + + + + +E K Sbjct: 908 -ESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDN 966 Query: 545 DIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYLKAENTRLNAELLKEKESKKRLEA 604 +I + K+ L +E+ + Q E K E + L +E +KR Sbjct: 967 CEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNV 1026 Query: 605 DIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKDENEFLTEQL 664 DI E ++ E L+ LE V Q+E + I + E + +T L Sbjct: 1027 DI-------------LKEKIRPEEQLRKKLE----VKQQLEQTLRIQDI--ELKSVTSNL 1067 Query: 665 SETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMK-------------E 711 ++ + D F + + + KK +A+ ++ + Q Q +E K E Sbjct: 1068 NQVSHTHESENDLFHE--NCMLKKEIAMLKLEVATLKHQHQVKENKYFEDIKILQEKNAE 1125 Query: 712 MYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKE 755 + + K T + + E++ L EN L +L + KE Sbjct: 1126 LQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKLKEKQDKE 1169 Score = 50.8 bits (120), Expect = 5e-06 Identities = 114/569 (20%), Positives = 217/569 (38%), Gaps = 93/569 (16%) Query: 297 TKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQ 356 T+ C+PE + + + +N + E P K + KP+ E++ A + KN Q Sbjct: 503 TQVCIPESMYQKVME---------INREVEELPEKPSAFKPAVEMQKTVPNKAFELKNEQ 553 Query: 357 TLRAEQALPVASEEEQERHERSEKKQP-------QVKEGNNTNKSEKIQLSENICDSTSS 409 TLRA Q P S+++ + + + P V T++ E LS + +S Sbjct: 554 TLRAAQMFPSESKQKDDEENSWDSESPCETVSQKDVYLPKATHQKEFDTLSGKLEESPVK 613 Query: 410 AAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNV-------------NMLY 456 + T RK+ P K E DR T K E+ +K + L Sbjct: 614 DGLLKPTCGRKV------SLPNKALELKDRETFKAESPDKDGLLKPTCGRKVSLPNKALE 667 Query: 457 KKNREELERKEKQ---YKKEVEAKQLEPTVQSLEMKS----KTARNTPNRDFHNHEEMKG 509 K+RE L+ + K +++ ++LE+K K A+ P+ +E + Sbjct: 668 LKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAAQMFPSESKQKDDE-EN 726 Query: 510 LMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITE 569 D L+ +L+ ++C K + ++ + ++ + + L+ + Sbjct: 727 SWDFESFLE---TLLQNDVCLPKATHQKEFDTLSGKLEESPDKDGLLKPTCGMK------ 777 Query: 570 TAFRYQQELNYLKAENTRLNAELLKEKESKKRLE-ADIESYQSRLAAAISKHSESVKTER 628 + N L LK++E+ K + + +ES S +++S+S K E Sbjct: 778 -----------ISLPNKALE---LKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEE 823 Query: 629 NLKLALER--TRDVSVQVEMSSAI---SKVKDENEFLTEQLSETQIKFNALKDKFRKTRD 683 + L + T+ V+ Q E I + N+ T +L + + + D Sbjct: 824 DFNLTTKEGATKTVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSD 883 Query: 684 SLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAE--AKVNNSTGKWNCVEERICHLQREN 741 + + L T Q ++ T + +E E + E ++ NS + L+ ++ Sbjct: 884 TQNYECLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADS 943 Query: 742 AWLVQQLDDV-------HQKEDHKEIVTN-----------IQRGFIESGKKDLVLEEKSK 783 L + LD + K+D+ E +T +Q+ E+ + LE + Sbjct: 944 TTLSKILDALPSCERGRELKKDNCEQITAKMEQTKNKFCVLQKELSEAKEIKSQLENQKA 1003 Query: 784 KLMNECDHLKESLFQYEREKTEGVVSIKE 812 K E ++ +L Q E EK V +KE Sbjct: 1004 KWEQELCSVRLTLNQ-EEEKRRNVDILKE 1031 >gi|149363642 coiled-coil domain containing 144A [Homo sapiens] Length = 1427 Score = 272 bits (696), Expect = 8e-73 Identities = 188/490 (38%), Positives = 272/490 (55%), Gaps = 67/490 (13%) Query: 397 IQLSENICDSTS----------SAAAGRLTQQRKIGKTYPQQFPKKLKEEHD-RCTLKQE 445 ++L N CD + S L++ +K Q + KE +D R LKQE Sbjct: 649 LKLKNNHCDQLTVKLKQMENMVSVLQNELSETKKTKLQLELQKIEWEKELYDLRLALKQE 708 Query: 446 NEEKTNVNMLYKKNREELERKEKQYKKEVEAKQ-------------------LEPTVQ-- 484 NEEK N +MLY K+ E+L KE++ K VE KQ L+ VQ Sbjct: 709 NEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKELRTVRNNLDLVVQER 768 Query: 485 ----------------------SLEMKSKTARNTPNRDF-HNHEEMKGLMDENCILKADI 521 S + + + AR N + H H++ K L E+C+L+ +I Sbjct: 769 NDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDCMLQEEI 828 Query: 522 AILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNYL 581 A+LR EI T+KN N +KE KY +DI+ VKE N L+K IKLNEE +TET +Y +LN L Sbjct: 829 ALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNL 888 Query: 582 KAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRD-- 639 AEN LN+EL K++++RLE ++ESY+ RLAAA+ +S +T R+LKL +RTR Sbjct: 889 TAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQS-QTARDLKLDFQRTRQEW 947 Query: 640 VSVQVEMSSAISKVKDENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDL 699 V + +M +S ++ +NE L+E+LS + K N+L+ + TRD+L ++SL LE VQ DL Sbjct: 948 VRLHDKMKVDMSGLQAKNEILSEKLSNAESKINSLQIQLHNTRDALGRESLILERVQRDL 1007 Query: 700 SQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKE 759 SQTQ Q +E ++MYQ ++K+ K VEER+ LQ EN L QQLDD H+K + +E Sbjct: 1008 SQTQCQKKETEQMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQE 1067 Query: 760 IVTN-IQRGF--------IESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSI 810 ++ IQ F ES K+ L L+EK+K+LM+E +HLKE + Q E+EK + + Sbjct: 1068 KTSSTIQDQFHSAAKNLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDL 1127 Query: 811 KEDKYFQTSR 820 E + SR Sbjct: 1128 TEAQETVPSR 1137 Score = 55.8 bits (133), Expect = 2e-07 Identities = 99/483 (20%), Positives = 198/483 (40%), Gaps = 84/483 (17%) Query: 363 ALPVASEEEQERHERSEKKQPQVKEGNNTN---------KSEKIQLSENICD------ST 407 +LP S+ E + E +Q K N N K E +QL +++ + S Sbjct: 478 SLPPDSDRTSEVYLHEELQQDMQKFKNEVNTLEEEFLALKKEDVQLHKDVEEEMEKHRSN 537 Query: 408 SSAAAGRLTQQRKIGKT---YPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELE 464 S+ +G LT +G QQ P+K EHDR K NE+ N +Y E + Sbjct: 538 STELSGTLTDGTTVGNDDDGLNQQIPRKENGEHDRPADKTSNEKNEVKNQIY----PEAD 593 Query: 465 RKEKQYKKEVEAKQLEPT----------VQSLEMKSKTARNTPNRDFHNHEEMKGLMDEN 514 + E+ ++ E + ++ L M+ K + + P + D Sbjct: 594 FADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPR-----------IQDTF 642 Query: 515 CILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRY 574 C+ + + L+ C D L + K ++++ V + + K KL E+ + Sbjct: 643 CLCE-HLLKLKNNHC----DQLTVKLKQMENMVSVLQNELSETKKTKLQLEL---QKIEW 694 Query: 575 QQELN----YLKAEN-TRLNAELLKEKESKK-RLEAD----IESYQSRLAAAISKHSESV 624 ++EL LK EN + NA++L K+S++ R++ + + + +L + + + + Sbjct: 695 EKELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRRLVKEL 754 Query: 625 KTER-NLKLALERTRDVSVQVE-------MSSAISKVKDENEFLTEQLSETQIKFNALKD 676 +T R NL L ++ D Q+ + I K + + + ++I K+ Sbjct: 755 RTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKKMNSEISHRHQKE 814 Query: 677 KFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEA------------KVNNST 724 K D + ++ +AL ++ D + Q + +E K+ +++ EA K+N T Sbjct: 815 KDLFHEDCMLQEEIALLRLEIDTIKNQNKQKE-KKYFEDIEAVKEKNDNLQKIIKLNEET 873 Query: 725 GKWNCVE--ERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKS 782 ++ ++ +L EN L +L++ Q ++ EI R + + +D + + Sbjct: 874 LTETILQYSGQLNNLTAENKILNSELENGKQNQERLEIEMESYRCRLAAAVRDCDQSQTA 933 Query: 783 KKL 785 + L Sbjct: 934 RDL 936 Score = 32.3 bits (72), Expect = 1.8 Identities = 16/32 (50%), Positives = 21/32 (65%) Query: 353 KNVQTLRAEQALPVASEEEQERHERSEKKQPQ 384 +N ++ AEQ + SEEEQER + E KQPQ Sbjct: 215 ENKESKEAEQDSELTSEEEQERLKGCENKQPQ 246 >gi|153791352 prostate, ovary, testis expressed protein on chromosome 2 [Homo sapiens] Length = 1075 Score = 270 bits (691), Expect = 3e-72 Identities = 204/606 (33%), Positives = 311/606 (51%), Gaps = 92/606 (15%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y +R +L K+HRAA G + + R D++ DKQ RTALHLA A+G Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKQDKQKRTALHLASANG 184 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + +VV LL++R+CQ++V D + RT LI+AV CQE+ CA++LLEHG +PN+ D YGNT LH Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+K+KA+ +A+DR Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE-------KVSEPLPG 311 + K S+ S+ E + + E S++ +++ PE +V E + Sbjct: 365 MLKISSE-NSNPEQDLKLTSEEESQRFKGSENSQPEKMSQE--PEINKDGDREVEEEM-- 419 Query: 312 SSHEKGN-----RIVNG--QGEGPPAKHPSLKPST------------------EVEDPAV 346 HE N + NG G G P K T E+ Sbjct: 420 KKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICELLSDYK 479 Query: 347 KGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVK-------------------- 386 + + + + + EQ L + SEEE +R + SE QP+ + Sbjct: 480 EKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAI 539 Query: 387 EGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLKEEH----D 438 E ++S + EN+ T+ A AG L RK QQFP EE+ Sbjct: 540 EEMKKHRSTHVGFPENL---TNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQ 596 Query: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498 T KQ EE+ N +L+ E L +EKQ +E + + SL K + Sbjct: 597 NDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE------- 641 Query: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558 K ++ EN L+ +IA+LR E+ TMK+ + +E KYL+DI+ VK+ N L K Sbjct: 642 ---------KDILHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKRNDNLLK 692 Query: 559 YIKLNE 564 ++LNE Sbjct: 693 ALQLNE 698 >gi|134133226 protein expressed in prostate, ovary, testis, and placenta 2 [Homo sapiens] Length = 1075 Score = 270 bits (690), Expect = 4e-72 Identities = 205/611 (33%), Positives = 308/611 (50%), Gaps = 102/611 (16%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y +R +L K+HRAA G + + R D++ DKQ RTALHLA A+G Sbjct: 125 DSAFMEPRYHVRGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKKDKQKRTALHLASANG 184 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + +VV LL++R+CQ++V D + RT LI+AV CQE+ CA++LLEHG +PN+ D YGNT LH Sbjct: 185 NSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+K+KA+ +A+DR Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPL--------- 309 + K S+ S+ E + + E S++ PEK+S+ L Sbjct: 365 MLKISSE-NSNPEQELKLTSEEESQRFKGSENSQ---------PEKMSQELEINKDGDRE 414 Query: 310 ---PGSSHEKGN-----RIVNG--QGEGPPAKHPSLKPST------------------EV 341 HE N + NG G G P K T E+ Sbjct: 415 VEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQRKSRTPENQQFPDNESEEYHRICEL 474 Query: 342 EDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVK--------------- 386 + + + + + EQ L + SEEE +R + SE QP+ + Sbjct: 475 LSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELE 534 Query: 387 -----EGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLKEEH 437 E + S + EN+ T+ A AG L RK QQFP EE+ Sbjct: 535 NFMAIEEMKKHGSTHVGFPENL---TNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEY 591 Query: 438 ----DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTA 493 T KQ EE+ N +L+ E L +EKQ +E + + SL K + Sbjct: 592 HSDEQNDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE-- 641 Query: 494 RNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETN 553 K ++ EN L+ +IA+LR E+ TMK+ + +E KYL+DI+ VK+ N Sbjct: 642 --------------KDVLHENSTLREEIAMLRLELDTMKHQSQLREKKYLEDIESVKKKN 687 Query: 554 AALEKYIKLNE 564 L K ++LNE Sbjct: 688 DNLLKALQLNE 698 >gi|113413200 PREDICTED: similar to protein expressed in prostate, ovary, testis, and placenta 2 [Homo sapiens] Length = 1038 Score = 266 bits (681), Expect = 4e-71 Identities = 205/606 (33%), Positives = 311/606 (51%), Gaps = 92/606 (15%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y +R +L K+HRAA G A + + R D++ DKQ RTALHLA A+G Sbjct: 88 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 147 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + VV LL++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH Sbjct: 148 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+K+KA+ +A+DR Sbjct: 208 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 267 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K Sbjct: 268 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 327 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE-------KVSEPLPG 311 + K S+ S+ E + + E S++ +++ PE +V E + Sbjct: 328 MLKISSE-NSNPEQDLKLTSEEESQRFKGSENSQPEKMSQE--PEINKDGDREVEEEM-- 382 Query: 312 SSHEKGN-----RIVNG--QGEGPPAKHPSLKPST------------------EVEDPAV 346 HE N + NG G G P K T E+ Sbjct: 383 KKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYK 442 Query: 347 KGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVK-------------------- 386 + + + + + EQ L + SEEE +R + SE QP+ + Sbjct: 443 EKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAI 502 Query: 387 EGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLKEEH----D 438 E + S + EN+ T+ A AG L RK QQFP EE+ Sbjct: 503 EEMKKHGSTHVGFPENL---TNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQ 559 Query: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498 T KQ EE+ N +L+ E L +EKQ +E + + SL K + Sbjct: 560 NDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE------- 604 Query: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558 RDF + EN +L+ +IA+LR E+ TMK+ + ++ KYL+DI+ VK+ N L K Sbjct: 605 RDF---------LHENSMLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLK 655 Query: 559 YIKLNE 564 ++LNE Sbjct: 656 ALQLNE 661 >gi|88953571 PREDICTED: similar to protein expressed in prostate, ovary, testis, and placenta 2 isoform 2 [Homo sapiens] Length = 1075 Score = 265 bits (677), Expect = 1e-70 Identities = 203/606 (33%), Positives = 308/606 (50%), Gaps = 92/606 (15%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y +R +L K+HRAA G A + + R D++ DKQ RTALHLA A+G Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + VV LL++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+K+KA+ +A+DR Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE-------KVSEPLPG 311 + K S+ S+ E + + E S++ +++ PE +V E + Sbjct: 365 MLKISSE-NSNPEQDLKLTSEEESQRFKGSENSQPEKMSQE--PEINKDGDREVEEEM-- 419 Query: 312 SSHEKGN-----RIVNG--QGEGPPAKHPSLKPST------------------EVEDPAV 346 HE N + NG G G P K T E+ Sbjct: 420 KKHESNNVGLLENLSNGVTAGNGDDGLIPQRKSRTPENQQFPDNESEEYHRICELVSDYK 479 Query: 347 KGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVK-------------------- 386 + + + + + EQ L + SEEE +R + SE QP+ + Sbjct: 480 EKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEINKDGDRELENFMAI 539 Query: 387 EGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLKEEH----D 438 E + S + EN+ T+ A AG L RK QQFP EE+ Sbjct: 540 EEMKKHGSTHVGFPENL---TNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQ 596 Query: 439 RCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPN 498 T KQ EE+ N +L+ E L +EKQ +E + + SL K + Sbjct: 597 NDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE------- 641 Query: 499 RDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEK 558 K + EN L+ +IA+LR E+ TMK+ + ++ KYL+DI+ VK+ N L K Sbjct: 642 ---------KDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKNDNLLK 692 Query: 559 YIKLNE 564 ++LNE Sbjct: 693 ALQLNE 698 >gi|239741769 PREDICTED: similar to protein expressed in prostate, ovary, testis, and placenta 2 [Homo sapiens] Length = 952 Score = 248 bits (633), Expect = 2e-65 Identities = 182/550 (33%), Positives = 282/550 (51%), Gaps = 103/550 (18%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y +R +L K+HRAA G A + + R D++ DKQ RTALHLA A+G Sbjct: 125 DSAFVEPRYHVRREDLDKLHRAAWWGKVARKDLIVMLRDTDVNKQDKQKRTALHLASANG 184 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + VV LL++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH Sbjct: 185 NSGVVKLLLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 244 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+K+KA+ +A+DR Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQ 364 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318 + L++ S ++ ++DL + + E+ S+ GS + Sbjct: 365 M--------------------LKISSENSNPEQDLKLTS-----EEESQRFKGSENS--- 396 Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERS 378 +P ++P + R+ EEE ++H + Sbjct: 397 -----------------QPEKMSQEPEINKDGDRE--------------VEEEMKKHGST 425 Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEH- 437 P+ N TN +T+ L RK QQFP EE+ Sbjct: 426 HVGFPE----NLTN------------GATAGNGDDGLIPPRKSRTPESQQFPDTENEEYH 469 Query: 438 ---DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTAR 494 T KQ EE+ N +L+ E L +EKQ +E + + SL K + Sbjct: 470 SDEQNDTQKQFCEEQ-NTGILHD---EILIHEEKQ----IEVVEKMNSELSLSCKKE--- 518 Query: 495 NTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNA 554 K + EN L+ +IA+LR E+ TMK+ + ++ KYL+DI+ VK+ N Sbjct: 519 -------------KDFLHENSTLREEIAMLRLELDTMKHQSQLRKKKYLEDIESVKKKND 565 Query: 555 ALEKYIKLNE 564 L K ++LNE Sbjct: 566 NLLKALQLNE 575 >gi|239741786 PREDICTED: kappa-actin [Homo sapiens] Length = 924 Score = 246 bits (628), Expect = 6e-65 Identities = 186/554 (33%), Positives = 284/554 (51%), Gaps = 102/554 (18%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y + +L K+HRAA G + + R D++ DKQ RTALHLA A+G Sbjct: 88 DSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKRDKQKRTALHLASANG 147 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + +VV L+++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH Sbjct: 148 NSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YAVY+E +A+ LL +GA IE+ +K TPLL I +K+++V+FL+K+KA+ +A+DR Sbjct: 208 YAVYNEDKLMAKALLLYGADIESKNKHGLTPLLLGIHEQKQQVVKFLIKKKANLNALDRY 267 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV+ LL+QNIDV +QD G+ A +YA+S H I Q + ++K+K Sbjct: 268 GRTALILAVCCGSANIVSPLLEQNIDVSSQD-XGQTAREYAVSSHHHVICQLLSDYKEKQ 326 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318 + K S+ S+ E + + E L S++ PEK+S+ Sbjct: 327 MLKISSE-NSNPEQDLKLTSEEESQKLKGSENSQ---------PEKMSQ----------E 366 Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERS 378 +N G+ E+ED +A EEE ++H Sbjct: 367 PEINKDGD------------RELED---------------------FMAIEEEMKKH--- 390 Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLK 434 S + EN+ T+ AAAG L RK QQFP Sbjct: 391 --------------GSTHVGFPENL---TNGAAAGNGDDGLIPPRKSRTPESQQFPDTEN 433 Query: 435 EEH----DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKS 490 EE+ T KQ +EE+ N +L E L +EKQ +E+ Sbjct: 434 EEYHSDEQNDTQKQLSEEQ-NTGIL---QDEILXHEEKQ----------------IEVAE 473 Query: 491 KTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVK 550 K + P ++++ K + EN L+ ++A+LR E+ MK+ + +E KYL++I+ V+ Sbjct: 474 KKMNSGPGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVE 533 Query: 551 ETNAALEKYIKLNE 564 + N L K ++LNE Sbjct: 534 KKNDNLLKALQLNE 547 >gi|239753333 PREDICTED: actin, beta-like 3 [Homo sapiens] Length = 924 Score = 246 bits (627), Expect = 8e-65 Identities = 185/554 (33%), Positives = 284/554 (51%), Gaps = 102/554 (18%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y + +L K+HRAA G + + R D++ DKQ RTALHLA A+G Sbjct: 88 DSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKRDKQKRTALHLASANG 147 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + +VV L+++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH Sbjct: 148 NSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YAVY+E +A+ LL +GA IE+ +K TPLL I +K+++V+FL+K+KA+ +A+DR Sbjct: 208 YAVYNEDKLMAKALLLYGADIESKNKHGLTPLLLGIHEQKQQVVKFLIKKKANLNALDRY 267 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV+ LL+QN+DV +QD G+ A +YA+S H I Q + ++K+K Sbjct: 268 GRTALILAVCCGSASIVSPLLEQNVDVSSQD-XGKTAREYAVSSHHHVICQLLSDYKEKQ 326 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318 + K S+ S+ E + + E L S++ PEK+S+ Sbjct: 327 MLKISSE-NSNPEQDLKLTSEEESQRLKGSENSQ---------PEKMSQ----------E 366 Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERS 378 +N G+ E+ED +A EEE ++H Sbjct: 367 PEINKDGD------------RELED---------------------FMAIEEEMKKH--- 390 Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLK 434 S + EN+ T+ AAAG L RK QQFP Sbjct: 391 --------------GSTHVGFPENL---TNGAAAGNGDDGLIPPRKSRTPESQQFPDTEN 433 Query: 435 EEH----DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKS 490 EE+ T KQ +EE+ N +L E L +EKQ +E+ Sbjct: 434 EEYHSDEQNDTQKQLSEEQ-NTGIL---QDEILXHEEKQ----------------IEVAE 473 Query: 491 KTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVK 550 K + P ++++ K + EN L+ ++A+LR E+ MK+ + +E KYL++I+ V+ Sbjct: 474 KKMNSGPGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVE 533 Query: 551 ETNAALEKYIKLNE 564 + N L K ++LNE Sbjct: 534 KKNDNLLKALQLNE 547 >gi|239747898 PREDICTED: actin, beta-like 3 [Homo sapiens] Length = 924 Score = 246 bits (627), Expect = 8e-65 Identities = 185/554 (33%), Positives = 284/554 (51%), Gaps = 102/554 (18%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y + +L K+HRAA G + + R D++ DKQ RTALHLA A+G Sbjct: 88 DSAFMDPRYHVHGEDLDKLHRAAWWGKVPRKDLIVMLRDTDVNKRDKQKRTALHLASANG 147 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + +VV L+++R+CQ++V D + RT L +AV CQE+ CA++LLEHG +PN+ D YGNT LH Sbjct: 148 NSEVVKLVLDRRCQLNVLDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYGNTTLH 207 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YAVY+E +A+ LL +GA IE+ +K TPLL I +K+++V+FL+K+KA+ +A+DR Sbjct: 208 YAVYNEDKLMAKALLLYGADIESKNKHGLTPLLLGIHEQKQQVVKFLIKKKANLNALDRY 267 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV+ LL+QN+DV +QD G+ A +YA+S H I Q + ++K+K Sbjct: 268 GRTALILAVCCGSASIVSPLLEQNVDVSSQD-XGKTAREYAVSSHHHVICQLLSDYKEKQ 326 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318 + K S+ S+ E + + E L S++ PEK+S+ Sbjct: 327 MLKISSE-NSNPEQDLKLTSEEESQRLKGSENSQ---------PEKMSQ----------E 366 Query: 319 RIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERS 378 +N G+ E+ED +A EEE ++H Sbjct: 367 PEINKDGD------------RELED---------------------FMAIEEEMKKH--- 390 Query: 379 EKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGR----LTQQRKIGKTYPQQFPKKLK 434 S + EN+ T+ AAAG L RK QQFP Sbjct: 391 --------------GSTHVGFPENL---TNGAAAGNGDDGLIPPRKSRTPESQQFPDTEN 433 Query: 435 EEH----DRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKS 490 EE+ T KQ +EE+ N +L E L +EKQ +E+ Sbjct: 434 EEYHSDEQNDTQKQLSEEQ-NTGIL---QDEILXHEEKQ----------------IEVAE 473 Query: 491 KTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVK 550 K + P ++++ K + EN L+ ++A+LR E+ MK+ + +E KYL++I+ V+ Sbjct: 474 KKMNSGPGTLSLSYKKEKDFLHENSTLQEEVAMLRLELDIMKHQSQLREKKYLEEIESVE 533 Query: 551 ETNAALEKYIKLNE 564 + N L K ++LNE Sbjct: 534 KKNDNLLKALQLNE 547 >gi|53828703 POTE ankyrin domain family, member A isoform 2 [Homo sapiens] Length = 498 Score = 240 bits (612), Expect = 4e-63 Identities = 140/344 (40%), Positives = 210/344 (61%), Gaps = 20/344 (5%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D +T Y +R +L K+HRAA G+ + + R ++ DK+ RTALHLACA+G Sbjct: 51 DSAFTEPRYHVRREDLGKLHRAAWWGEVPRADLIVMLRGPGINKRDKKKRTALHLACANG 110 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + +VV+LL++R+CQ+ V D + RT LI+AV CQE+ CA++LL+HG +PNL D+YGNTALH Sbjct: 111 NSEVVSLLLDRQCQLHVFDSKKRTALIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALH 170 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YAVY+E +A+ LL +GA IE+ +K TPLL A+ +K++MV+FL+K+KA+ +A+DR Sbjct: 171 YAVYNEDKLMAKTLLLYGADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRF 230 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV++LL+QNIDVF+QD+ G+ AEDYA+S H + I Q + ++K+ Sbjct: 231 GRTALILAVRCGSASIVSLLLQQNIDVFSQDVFGQTAEDYAVSSHHSIICQLLSDYKENQ 290 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVAT------KQCVPEKVSEPLPGS 312 + S S+ E + + E L S++ T K C E E Sbjct: 291 MPNNSSG-NSNPEQDLKLTSEEEPQRLKGSENSQHEKVTQEPDINKDCDREVEEEMQKHG 349 Query: 313 SHEKG------NRIVNGQGEG------PPAKHPSLK-PSTEVED 343 S+ G + G G+G KH + + P+TE+E+ Sbjct: 350 SNNVGLSENLTDGAAAGNGDGGLVPQRKSRKHENQQFPNTEIEE 393 >gi|52856434 POTE ankyrin domain family, member G [Homo sapiens] Length = 508 Score = 231 bits (590), Expect = 2e-60 Identities = 140/396 (35%), Positives = 230/396 (58%), Gaps = 26/396 (6%) Query: 19 DHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACASG 78 D + Y +R +L K+HRAA G + + + D++ DKQ RTALHLA A+G Sbjct: 125 DSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLASANG 184 Query: 79 HVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALH 138 + +VV LL++R+CQ+++ D + RT L +AV C+E+ CA++LLEHG +PN+ D YGNTALH Sbjct: 185 NSEVVKLLLDRRCQLNILDNKKRTALTKAVQCREDECALMLLEHGTDPNIPDEYGNTALH 244 Query: 139 YAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKRKASSHAVDRL 198 YA+Y+E +A+ LL +GA IE+ +K TPLL + +K+++V+FL+K+KA+ +A+DR Sbjct: 245 YAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNALDRY 304 Query: 199 RRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKI 258 R+AL+LAV S IV++LL+QNIDV +QD+ G+ A +YA+S H I Q + ++K+K Sbjct: 305 GRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHNVICQLLSDYKEKQ 364 Query: 259 LKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGN 318 + K S+ S+ E + + E L S++ PE++S+ ++ G+ Sbjct: 365 MLKVSSE-NSNPEQDLKLTSEEESQRLKGSENSQ---------PEEMSQ--EPEINKGGD 412 Query: 319 RIVNGQGEGPPAKH---PSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERH 375 R V + + + H P P+ D G + + +T ++Q +E EQ Sbjct: 413 RKVEEEMKKHGSTHMGFPENLPNGATADNGDDGLIPPRKSRTPESQQF--PDTENEQYHS 470 Query: 376 ERSEKKQPQVKEGNNT---------NKSEKIQLSEN 402 + Q Q+ E NT ++ ++I+++EN Sbjct: 471 DEQNDTQKQLSEEQNTGILQDEILIHEEKQIEVAEN 506 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.127 0.346 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,172,905 Number of Sequences: 37866 Number of extensions: 1364598 Number of successful extensions: 14127 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 492 Number of HSP's successfully gapped in prelim test: 1024 Number of HSP's that attempted gapping in prelim test: 6626 Number of HSP's gapped (non-prelim): 4890 length of query: 823 length of database: 18,247,518 effective HSP length: 111 effective length of query: 712 effective length of database: 14,044,392 effective search space: 9999607104 effective search space used: 9999607104 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.