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Search of human proteins with 6041667
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6041667 dopachrome tautomerase isoform 1 [Homo sapiens]
(519 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6041667 dopachrome tautomerase isoform 1 [Homo sapiens] 1109 0.0
gi|193788640 dopachrome tautomerase isoform 2 [Homo sapiens] 1092 0.0
gi|4507757 tyrosinase-related protein 1 precursor [Homo sapiens] 512 e-145
gi|4507753 tyrosinase precursor [Homo sapiens] 397 e-110
gi|66346700 N-acetylglucosamine-1-phosphodiester alpha-N-acetylg... 36 0.097
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 35 0.17
gi|24041035 notch 2 preproprotein [Homo sapiens] 33 0.63
gi|153946395 tenascin C precursor [Homo sapiens] 33 0.63
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 33 0.63
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 32 1.1
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 32 1.1
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 32 1.4
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 32 1.4
gi|32567786 keratin 6L [Homo sapiens] 32 1.8
gi|148613884 netrin 1 [Homo sapiens] 32 1.8
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 32 1.8
gi|13324710 interleukin 3 receptor, alpha precursor [Homo sapiens] 31 2.4
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 31 2.4
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 31 2.4
gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains) ... 31 3.1
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 31 3.1
gi|21264602 laminin alpha 5 [Homo sapiens] 30 4.1
gi|113206024 mucin 1 isoform 5 precursor [Homo sapiens] 30 5.3
gi|148833508 notch1 preproprotein [Homo sapiens] 30 5.3
gi|4759146 slit homolog 2 [Homo sapiens] 30 5.3
gi|93204871 netrin 4 [Homo sapiens] 30 5.3
gi|5453810 netrin 3 [Homo sapiens] 30 5.3
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 30 7.0
gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo ... 30 7.0
gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo ... 30 7.0
>gi|6041667 dopachrome tautomerase isoform 1 [Homo sapiens]
Length = 519
Score = 1109 bits (2868), Expect = 0.0
Identities = 519/519 (100%), Positives = 519/519 (100%)
Query: 1 MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQ 60
MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQ
Sbjct: 1 MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQ 60
Query: 61 CTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER 120
CTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER
Sbjct: 61 CTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER 120
Query: 121 KKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCS 180
KKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCS
Sbjct: 121 KKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCS 180
Query: 181 VYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESF 240
VYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESF
Sbjct: 181 VYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESF 240
Query: 241 ALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCN 300
ALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCN
Sbjct: 241 ALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCN 300
Query: 301 GTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGT 360
GTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGT
Sbjct: 301 GTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGT 360
Query: 361 LDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQE 420
LDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQE
Sbjct: 361 LDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQE 420
Query: 421 LAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTL 480
LAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTL
Sbjct: 421 LAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTL 480
Query: 481 VALVGLFVLLAFLQYRRLRKGYTPLMETHLSSKRYTEEA 519
VALVGLFVLLAFLQYRRLRKGYTPLMETHLSSKRYTEEA
Sbjct: 481 VALVGLFVLLAFLQYRRLRKGYTPLMETHLSSKRYTEEA 519
>gi|193788640 dopachrome tautomerase isoform 2 [Homo sapiens]
Length = 552
Score = 1092 bits (2824), Expect = 0.0
Identities = 519/552 (94%), Positives = 519/552 (94%), Gaps = 33/552 (5%)
Query: 1 MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQ 60
MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQ
Sbjct: 1 MSPLWWGFLLSCLGCKILPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQ 60
Query: 61 CTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER 120
CTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER
Sbjct: 61 CTEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER 120
Query: 121 KKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCS 180
KKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCS
Sbjct: 121 KKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCS 180
Query: 181 VYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESF 240
VYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESF
Sbjct: 181 VYDFFVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESF 240
Query: 241 ALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCN 300
ALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCN
Sbjct: 241 ALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCN 300
Query: 301 GTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGT 360
GTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGT
Sbjct: 301 GTYEGLLRRNQMGRNSMKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDKADGT 360
Query: 361 LDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVV-------------------------- 394
LDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVV
Sbjct: 361 LDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVISNRLLYNATTNILEHVRKEKATKEL 420
Query: 395 -------LHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLT 447
LHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLT
Sbjct: 421 PSLHVLVLHSFTDAIFDEWMKRFNPPADAWPQELAPIGHNRMYNMVPFFPPVTNEELFLT 480
Query: 448 SDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTLVALVGLFVLLAFLQYRRLRKGYTPLME 507
SDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTLVALVGLFVLLAFLQYRRLRKGYTPLME
Sbjct: 481 SDQLGYSYAIDLPVSVEETPGWPTTLLVVMGTLVALVGLFVLLAFLQYRRLRKGYTPLME 540
Query: 508 THLSSKRYTEEA 519
THLSSKRYTEEA
Sbjct: 541 THLSSKRYTEEA 552
>gi|4507757 tyrosinase-related protein 1 precursor [Homo sapiens]
Length = 537
Score = 512 bits (1319), Expect = e-145
Identities = 250/498 (50%), Positives = 329/498 (66%), Gaps = 17/498 (3%)
Query: 10 LSCLGCKILP-----GAQGQFPRVCMTVDSLVNKECCPRLGAESA---NVCGSQQGRGQC 61
L LGC P A+ QFPR C TV++L + CCP L S + CGS GRG+C
Sbjct: 6 LLSLGCIFFPLLLFQQARAQFPRQCATVEALRSGMCCPDLSPVSGPGTDRCGSSSGRGRC 65
Query: 62 TEVRADTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERK 121
V AD+RP S Y +DDRE+WP +FF+RTC C GNF+G+NCG C+ GW G C+++
Sbjct: 66 EAVTADSRPHSPQYPHDGRDDREVWPLRFFNRTCHCNGNFSGHNCGTCRPGWRGAACDQR 125
Query: 122 KPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGPNGTQPQFANCSV 181
++R+N+ LS +E+ F+ ALD+AK+ HP +VI T+ +LGP+G PQF N S+
Sbjct: 126 VL-IVRRNLLDLSKEEKNHFVRALDMAKRTTHPLFVIATRRSEEILGPDGNTPQFENISI 184
Query: 182 YDFFVWLHYYSVRDTLLGPGRP-YRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESF 240
Y++FVW HYYSV+ T LG G+ + +DFSH+GPAF+TWHRYHLL LE+D+Q ++ SF
Sbjct: 185 YNYFVWTHYYSVKKTFLGVGQESFGEVDFSHEGPAFLTWHRYHLLRLEKDMQEMLQEPSF 244
Query: 241 ALPYWNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCN 300
+LPYWNFATG+N CD+CTD L G+ D TLIS NS FS W VCDSL+DY+ L TLCN
Sbjct: 245 SLPYWNFATGKNVCDICTDDLMGSRSNFDSTLISPNSVFSQWRVVCDSLEDYDTLGTLCN 304
Query: 301 GTYEGLLRRNQMGRNS----MKLPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGFDK 356
T +G +RRN G + +LP +D+ CL + FD PPF+ NST SFRN +EG+
Sbjct: 305 STEDGPIRRNPAGNVARPMVQRLPEPQDVAQCLEVGLFDTPPFYSNSTNSFRNTVEGYSD 364
Query: 357 ADGTLDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADA 416
G D V SLHNL H FLNGT H + NDPIFV+LH+FTDA+FDEW++R+N
Sbjct: 365 PTGKYDPAVRSLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADIST 424
Query: 417 WPQELAPIGHNRMYNMVPFFPPVTNEELFLTS-DQLGYSYAIDLPVSVEETPGWPTTLLV 475
+P E APIGHNR YNMVPF+PPVTN E+F+T+ D LGY+Y I P P +
Sbjct: 425 FPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYTYEIQWPSREFSVP--EIIAIA 482
Query: 476 VMGTLVALVGLFVLLAFL 493
V+G L+ + +F ++L
Sbjct: 483 VVGALLLVALIFGTASYL 500
>gi|4507753 tyrosinase precursor [Homo sapiens]
Length = 529
Score = 397 bits (1019), Expect = e-110
Identities = 193/456 (42%), Positives = 280/456 (61%), Gaps = 15/456 (3%)
Query: 9 LLSCLGCKI--LPGAQGQFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQCTEVRA 66
LL+ L C + + G FPR C++ +L+ KECCP + + CG GRG C +
Sbjct: 2 LLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSP-CGQLSGRGSCQNILL 60
Query: 67 DTRPWSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERKKPPVI 126
P + DDRE WP F++RTC+C+GNF G+NCG+CKFG+ GPNC ++ ++
Sbjct: 61 SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRL-LV 119
Query: 127 RQNIHSLSPQEREQFLGALDLAKKRVHPDYVITTQHWLGLLGP--NGTQPQFANCSVYDF 184
R+NI LS E+++F L LAK + DYVI +G G NG+ P F + ++YD
Sbjct: 120 RRNIFDLSAPEKDKFFAYLTLAKHTISSDYVIP----IGTYGQMKNGSTPMFNDINIYDL 175
Query: 185 FVWLHYYSVRDTLLGPGRPYRAIDFSHQGPAFVTWHRYHLLCLERDLQRLIGNESFALPY 244
FVW+HYY D LLG +R IDF+H+ PAF+ WHR LL E+++Q+L G+E+F +PY
Sbjct: 176 FVWMHYYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPY 235
Query: 245 WNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSSWETVCDSLDDYNHLVTLCNGTYE 304
W++ +CD+CTD+ G P +P L+S S FSSW+ VC L++YN +LCNGT E
Sbjct: 236 WDWRDAE-KCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPE 294
Query: 305 GLLRRNQMGRNSMK---LPTLKDIRDCLSLQKFDNPPFFQNSTFSFRNALEGF-DKADGT 360
G LRRN + + LP+ D+ CLSL ++++ + + FSFRN LEGF G
Sbjct: 295 GPLRRNPGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGI 354
Query: 361 LDSQVMSLHNLVHSFLNGTNALPHSAANDPIFVVLHSFTDAIFDEWMKRFNPPADAWPQE 420
D+ S+HN +H ++NGT + +ANDPIF++ H+F D+IF++W++R P + +P+
Sbjct: 355 ADASQSSMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEA 414
Query: 421 LAPIGHNRMYNMVPFFPPVTNEELFLTSDQLGYSYA 456
APIGHNR MVPF P N + F++S LGY Y+
Sbjct: 415 NAPIGHNRESYMVPFIPLYRNGDFFISSKDLGYDYS 450
>gi|66346700 N-acetylglucosamine-1-phosphodiester
alpha-N-acetylglucosaminidase precursor [Homo sapiens]
Length = 515
Score = 35.8 bits (81), Expect = 0.097
Identities = 12/27 (44%), Positives = 16/27 (59%), Gaps = 1/27 (3%)
Query: 95 CKCTGNFAGYNCGD-CKFGWTGPNCER 120
C+C + G NC + C GW GP C+R
Sbjct: 378 CRCDAGWTGSNCSEECPLGWHGPGCQR 404
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 35.0 bits (79), Expect = 0.17
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 1/37 (2%)
Query: 87 PRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERKKP 123
P F RTC+ G GY C C+ G+TG CE+ P
Sbjct: 1620 PENMFSRTCESLGA-GGYRCTACEPGYTGQYCEQCGP 1655
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 33.1 bits (74), Expect = 0.63
Identities = 14/26 (53%), Positives = 15/26 (57%), Gaps = 1/26 (3%)
Query: 97 CTGNFAGYNCGDCKFGWTGPNCERKK 122
CTG +GY C C GW G NCE K
Sbjct: 734 CTGGLSGYKCL-CDAGWVGINCEVDK 758
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 33.1 bits (74), Expect = 0.63
Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 1/31 (3%)
Query: 95 CKCTGNFAGYNCGD-CKFGWTGPNCERKKPP 124
C GNF+ CG C+ GW GPNC + P
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECP 191
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 33.1 bits (74), Expect = 0.63
Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 4/51 (7%)
Query: 71 WSGPYILRNQDDRELWPRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCERK 121
W G + + ++ ++ P K CT + Y C +C GWTG NC +
Sbjct: 763 WEGNFCEQESNECKMNPCK---NNSTCTDLYKSYRC-ECTSGWTGQNCSEE 809
>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
Length = 317
Score = 32.3 bits (72), Expect = 1.1
Identities = 13/37 (35%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Query: 245 WNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSS 281
W+F GR C +C D+L ++ D+P S N+ ++S
Sbjct: 258 WDFKVGRGRCSLC-DELCPDSKSDEPVCASDNATYAS 293
>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
Length = 344
Score = 32.3 bits (72), Expect = 1.1
Identities = 13/37 (35%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Query: 245 WNFATGRNECDVCTDQLFGAARPDDPTLISRNSRFSS 281
W+F GR C +C D+L ++ D+P S N+ ++S
Sbjct: 258 WDFKVGRGRCSLC-DELCPDSKSDEPVCASDNATYAS 293
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 32.0 bits (71), Expect = 1.4
Identities = 13/26 (50%), Positives = 16/26 (61%)
Query: 98 TGNFAGYNCGDCKFGWTGPNCERKKP 123
TGN +G C DC+ G NCE+ KP
Sbjct: 354 TGNVSGGVCDDCQHNTMGRNCEQCKP 379
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 32.0 bits (71), Expect = 1.4
Identities = 12/28 (42%), Positives = 15/28 (53%), Gaps = 1/28 (3%)
Query: 95 CKCTGNFAGYNCGD-CKFGWTGPNCERK 121
C C F G C D C GW GP+C+ +
Sbjct: 802 CLCLPGFVGSRCQDVCPAGWYGPSCQTR 829
Score = 31.2 bits (69), Expect = 2.4
Identities = 36/128 (28%), Positives = 44/128 (34%), Gaps = 20/128 (15%)
Query: 9 LLSCLGCKILPGAQGQFPRVCMTVDSLVNKEC---CP--RLGAESANVCGSQQGRGQCTE 63
L CL A G C + +C CP R G +VCG QG C
Sbjct: 1218 LCGCLNGGSCDAATG----ACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAA-CDP 1272
Query: 64 VRADTRPWSGPYILRNQDDRELWPRKFF----HRTCKC-TGNFAGYNCGDCK--FGWTGP 116
V G +R + P+ F TC C G + G C GWTG
Sbjct: 1273 VTGTCLCPPGRAGVRCERG---CPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGR 1329
Query: 117 NCERKKPP 124
+CE PP
Sbjct: 1330 HCELACPP 1337
>gi|32567786 keratin 6L [Homo sapiens]
Length = 535
Score = 31.6 bits (70), Expect = 1.8
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Query: 338 PFFQNSTFSFRNALEGFDKADGTLDSQVMSLHNLVHSFLN--GTNALPHSAANDPIFVVL 395
P F+ S R+ L+ G LDS++ ++ +LV F N H+AA + FVVL
Sbjct: 193 PLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENE-FVVL 251
Query: 396 HSFTDAIF 403
DA +
Sbjct: 252 KKDVDAAY 259
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 31.6 bits (70), Expect = 1.8
Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 17/61 (27%)
Query: 79 NQDDRELWPRKFFHRT--------CKCTGNFA--------GYNCGDCKFGWTGPNCERKK 122
N+DD EL +F+ CKC G+ A C DC+ GP C+R K
Sbjct: 261 NEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCK 319
Query: 123 P 123
P
Sbjct: 320 P 320
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 31.6 bits (70), Expect = 1.8
Identities = 25/85 (29%), Positives = 34/85 (40%), Gaps = 18/85 (21%)
Query: 45 GAESANVCGSQQ--GRGQCTEVRADTR-----PWSGPYILRNQDDRELWPRKFFHRTC-- 95
G NVC S G C ++ + WSG + N D+ F C
Sbjct: 1136 GCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDE-------CFSNPCIH 1188
Query: 96 -KCTGNFAGYNCGDCKFGWTGPNCE 119
C+ A Y+C C+ G+TG NCE
Sbjct: 1189 GNCSDRVAAYHC-TCEPGYTGVNCE 1212
>gi|13324710 interleukin 3 receptor, alpha precursor [Homo sapiens]
Length = 378
Score = 31.2 bits (69), Expect = 2.4
Identities = 13/24 (54%), Positives = 19/24 (79%)
Query: 466 TPGWPTTLLVVMGTLVALVGLFVL 489
T W T+LL+ +GTL+ALV +FV+
Sbjct: 301 TRAWRTSLLIALGTLLALVCVFVI 324
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 31.2 bits (69), Expect = 2.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 8/57 (14%)
Query: 11 SCLGCKILPGAQGQFPRVCMTV---DSLVNKECCP---RLGAESANVCGSQQGRGQC 61
SCL CK PG G++ +C D++ K C P G + VC SQ G+ +C
Sbjct: 885 SCLICK--PGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCEC 939
Score = 29.6 bits (65), Expect = 7.0
Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Query: 87 PRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER 120
P F TC + G C C G+TGP CER
Sbjct: 814 PSNNFSPTCHLDRSL-GLICDGCPVGYTGPRCER 846
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 31.2 bits (69), Expect = 2.4
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 8/57 (14%)
Query: 11 SCLGCKILPGAQGQFPRVCMTV---DSLVNKECCP---RLGAESANVCGSQQGRGQC 61
SCL CK PG G++ +C D++ K C P G + VC SQ G+ +C
Sbjct: 885 SCLICK--PGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCEC 939
Score = 29.6 bits (65), Expect = 7.0
Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 1/34 (2%)
Query: 87 PRKFFHRTCKCTGNFAGYNCGDCKFGWTGPNCER 120
P F TC + G C C G+TGP CER
Sbjct: 814 PSNNFSPTCHLDRSL-GLICDGCPVGYTGPRCER 846
>gi|4758614 integrin, beta-like 1 (with EGF-like repeat domains)
[Homo sapiens]
Length = 494
Score = 30.8 bits (68), Expect = 3.1
Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 16/115 (13%)
Query: 12 CLGCKILPGAQG---QFPRVCMTVDSLVNKECCPRLGAESANVCGSQQGRGQCTEVRADT 68
C CK G G Q+P C N+ C S ++ S G C + D
Sbjct: 112 CGKCKCDQGWYGDACQYPTNCDLTKKKSNQMC-----KNSQDIICSNAGTCHCGRCKCDN 166
Query: 69 RPWSGPYILR--NQDDRELWPRKFFHRTCKCTGNFAGYNCGDC--KFGWTGPNCE 119
SG + DDRE T + G CG+C K GW G CE
Sbjct: 167 SDGSGLVYGKFCECDDREC----IDDETEEICGGHGKCYCGNCYCKAGWHGDKCE 217
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 30.8 bits (68), Expect = 3.1
Identities = 13/28 (46%), Positives = 13/28 (46%), Gaps = 1/28 (3%)
Query: 92 HRTCKCTGNFAGYNCGDCKFGWTGPNCE 119
H C GYNC C GW G NCE
Sbjct: 591 HHGGSCLDQPNGYNC-HCPHGWVGANCE 617
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 30.4 bits (67), Expect = 4.1
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)
Query: 40 CCPRLG--------AESANVCGSQQGRGQCTEVRADTRPWSGPYILRNQDDRELWPRKFF 91
CCP A SAN C S G T+ D P + R + + L
Sbjct: 336 CCPGFNQQPWKPATANSANECQSCNCYGHATDCYYD------PEVDRRRASQSL------ 383
Query: 92 HRTCKCTGNFAGYN-CGDCKFGWTGPNCERKKPPVIRQNIHSL 133
G + G C DC+ TG NCER P R H L
Sbjct: 384 ------DGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
Score = 29.6 bits (65), Expect = 7.0
Identities = 11/25 (44%), Positives = 14/25 (56%)
Query: 95 CKCTGNFAGYNCGDCKFGWTGPNCE 119
C C NF G +C C G+ GP C+
Sbjct: 515 CLCKPNFQGTHCELCAPGFYGPGCQ 539
Score = 29.3 bits (64), Expect = 9.1
Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 21/92 (22%)
Query: 48 SANVCGSQQGRGQCTEV-----------------RADTRPWSGPYILRN---QDDRELWP 87
S ++ G+ QG G C + R+ P P++ R + D
Sbjct: 380 SQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGT 439
Query: 88 RKFFHRTCKCTGNFAGYNCGDCKFGWTG-PNC 118
+ C C NF+G C C G+TG P+C
Sbjct: 440 CEDLTGRCYCRPNFSGERCDVCAEGFTGFPSC 471
Score = 29.3 bits (64), Expect = 9.1
Identities = 12/26 (46%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 95 CKCTGNFAGYNCGDCKFGWTG-PNCE 119
C C FAG +C C+ G+ G PNC+
Sbjct: 605 CLCQPEFAGPHCDRCRPGYHGFPNCQ 630
>gi|113206024 mucin 1 isoform 5 precursor [Homo sapiens]
Length = 203
Score = 30.0 bits (66), Expect = 5.3
Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 441 NEELFLTSDQLGYSYAIDLPVSVEE---TPGWPTTLLVVMGTLVALVGLFVL-LAFLQYR 496
N+ +F S L + P S + PGW LLV++ LVAL ++++ LA Q R
Sbjct: 76 NKGVFWASPILSSVSDVPFPFSAQSGAGVPGWGIALLVLVCVLVALAIVYLIALAVCQCR 135
Query: 497 RLRKG 501
R G
Sbjct: 136 RKNYG 140
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 30.0 bits (66), Expect = 5.3
Identities = 11/23 (47%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
Query: 97 CTGNFAGYNCGDCKFGWTGPNCE 119
C + GY C DC GW+G NC+
Sbjct: 730 CRDSLNGYKC-DCDPGWSGTNCD 751
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 30.0 bits (66), Expect = 5.3
Identities = 12/30 (40%), Positives = 20/30 (66%), Gaps = 2/30 (6%)
Query: 92 HRTCKCTGNFAGYNCGDCKFGWTGPNCERK 121
H TC+ + AG+ C +C+ GW GP C+++
Sbjct: 1343 HGTCQPSSQ-AGFTC-ECQEGWMGPLCDQR 1370
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 30.0 bits (66), Expect = 5.3
Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 16/51 (31%)
Query: 93 RTCKC----------------TGNFAGYNCGDCKFGWTGPNCERKKPPVIR 127
RTCKC +GN +G C DC+ G C+R KP R
Sbjct: 330 RTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 30.0 bits (66), Expect = 5.3
Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 7/36 (19%)
Query: 95 CKCTGNFA-------GYNCGDCKFGWTGPNCERKKP 123
CKC G+ + G+ DC+ G GP+C R KP
Sbjct: 255 CKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKP 290
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 29.6 bits (65), Expect = 7.0
Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 10/91 (10%)
Query: 41 CPR--LGAESANVCGSQQGRGQCTEVRADTRPWSGPYILRNQDDRELWPRKFFHRT--CK 96
CP G +N C + G G C + P R P ++ R CK
Sbjct: 567 CPEGLWGVNCSNTCTCKNG-GTCLPENGNCV--CAPGFRGPSCQRSCQPGRYGKRCVPCK 623
Query: 97 CTGN-FAGYNCGDCKF--GWTGPNCERKKPP 124
C + F + G C GWTGP+C + PP
Sbjct: 624 CANHSFCHPSNGTCYCLAGWTGPDCSQPCPP 654
>gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 29.6 bits (65), Expect = 7.0
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 115 GPNCERKKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYV---ITTQHWLGLLGPNG 171
G C +KP ++ N+H +++ FL L K+V Y+ + LGLLGPNG
Sbjct: 1280 GCQCCEEKPSIMVSNLHK-EYDDKKDFL--LSRKVKKVATKYISFCVKKGEILGLLGPNG 1336
>gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 29.6 bits (65), Expect = 7.0
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 115 GPNCERKKPPVIRQNIHSLSPQEREQFLGALDLAKKRVHPDYV---ITTQHWLGLLGPNG 171
G C +KP ++ N+H +++ FL L K+V Y+ + LGLLGPNG
Sbjct: 1280 GCQCCEEKPSIMVSNLHK-EYDDKKDFL--LSRKVKKVATKYISFCVKKGEILGLLGPNG 1336
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.463
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,719,110
Number of Sequences: 37866
Number of extensions: 1085946
Number of successful extensions: 2522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 2396
Number of HSP's gapped (non-prelim): 152
length of query: 519
length of database: 18,247,518
effective HSP length: 107
effective length of query: 412
effective length of database: 14,195,856
effective search space: 5848692672
effective search space used: 5848692672
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.