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Search of human proteins with 6005747
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005747 ring finger protein 2 [Homo sapiens]
(336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005747 ring finger protein 2 [Homo sapiens] 676 0.0
gi|51479192 ring finger protein 1 [Homo sapiens] 384 e-107
gi|31742478 ring finger protein 3 [Homo sapiens] 57 2e-08
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 54 3e-07
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 54 3e-07
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 54 3e-07
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 54 3e-07
gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens] 54 3e-07
gi|6005964 ring finger protein 110 [Homo sapiens] 51 2e-06
gi|33300663 polycomb group ring finger 5 [Homo sapiens] 50 2e-06
gi|109240538 polycomb group ring finger 1 [Homo sapiens] 50 2e-06
gi|15208660 tripartite motif protein 21 [Homo sapiens] 50 3e-06
gi|4508005 tripartite motif-containing 26 [Homo sapiens] 48 1e-05
gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens] 48 1e-05
gi|4506561 ring finger protein 4 [Homo sapiens] 47 2e-05
gi|62865604 tripartite motif protein 31 [Homo sapiens] 47 2e-05
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 47 2e-05
gi|30425428 deltex homolog 3 [Homo sapiens] 47 3e-05
gi|169160953 PREDICTED: hypothetical LOC644006 [Homo sapiens] 46 4e-05
gi|239747623 PREDICTED: hypothetical protein XP_002347917 [Homo ... 46 4e-05
gi|88943822 PREDICTED: hypothetical protein LOC644006 [Homo sapi... 46 4e-05
gi|60099474 tripartite motif-containing 61 [Homo sapiens] 46 4e-05
gi|22027630 TNF receptor-associated factor 6 [Homo sapiens] 46 5e-05
gi|4759254 TNF receptor-associated factor 6 [Homo sapiens] 46 5e-05
gi|23312364 ubiquitin-like with PHD and ring finger domains 2 [H... 45 9e-05
gi|37595555 ring finger protein 125 [Homo sapiens] 45 9e-05
gi|239048909 checkpoint with forkhead and ring finger domains is... 44 2e-04
gi|239048905 checkpoint with forkhead and ring finger domains is... 44 2e-04
gi|239048862 checkpoint with forkhead and ring finger domains is... 44 2e-04
gi|239048792 checkpoint with forkhead and ring finger domains is... 44 2e-04
>gi|6005747 ring finger protein 2 [Homo sapiens]
Length = 336
Score = 676 bits (1743), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN 60
MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN
Sbjct: 1 MSQAVQTNGTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKN 60
Query: 61 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY 120
TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY
Sbjct: 61 TMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEY 120
Query: 121 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS 180
EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS
Sbjct: 121 EAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGSGAEDNGDSSHCS 180
Query: 181 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD 240
NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD
Sbjct: 181 NASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIELVFRPHPTLMEKD 240
Query: 241 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG 300
DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG
Sbjct: 241 DSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQMNLDTASEKQYTIYIATASG 300
Query: 301 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK 336
QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK
Sbjct: 301 QFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK 336
>gi|51479192 ring finger protein 1 [Homo sapiens]
Length = 406
Score = 384 bits (985), Expect = e-107
Identities = 219/401 (54%), Positives = 256/401 (63%), Gaps = 77/401 (19%)
Query: 11 QPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHR 70
Q SKTWELSLYEL RTPQEAI DG EI VSPRSLHSELMCPICLDMLKNTMTTKECLHR
Sbjct: 8 QNASKTWELSLYELHRTPQEAIMDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHR 67
Query: 71 FCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSRDEYEAHQERVLAR 130
FC+DCI+TALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSR+EYEAHQ+RVL R
Sbjct: 68 FCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIR 127
Query: 131 INKHNNQQALSHSIEEGLKIQAMNRLQRGKK--------QQIENGSG--AEDNGDSSHCS 180
+++ +NQQALS SIEEGL++QAM+R QR ++ + G G E GD S
Sbjct: 128 LSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPGEGEGDGEDVS 187
Query: 181 NASTHSNQEAGPSNKRTK-----------------------TSDDSGLELDNNNAAMAID 217
+ S + GP+ KR + S+DSG
Sbjct: 188 SDSA-PDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGP 246
Query: 218 PVMDGA-------SEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALE 270
P GA EIELVFRPHP L+EK + QTRY+KT+GNATVDHLSKYLA+R+ALE
Sbjct: 247 PSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALE 306
Query: 271 ELRSKGESNQ-----------------------------------MNLDTASEKQYTIYI 295
R + E+ + +L+ SEKQYTIYI
Sbjct: 307 R-RQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYI 365
Query: 296 ATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAPTKEHK 336
A G FT LNGS +LELV+EK+WKV++P+EL YAPTK+ K
Sbjct: 366 APGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK 406
>gi|31742478 ring finger protein 3 [Homo sapiens]
Length = 242
Score = 57.0 bits (136), Expect = 2e-08
Identities = 61/291 (20%), Positives = 108/291 (37%), Gaps = 68/291 (23%)
Query: 45 LHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLR--- 101
+++ + C +C L + T ECLH FC C++ L N CPTCR + L+
Sbjct: 11 INAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEE-NNTCPTCRIVIHQSHPLQYIG 69
Query: 102 PDPNFDALISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKK 161
D ++ K+ P E E ++R L + +K + + K
Sbjct: 70 HDRTMQDIVYKLVPGLQEAEMRKQREF--------YHKLGMEVPGDIKGETCS-----AK 116
Query: 162 QQIENGSGAEDNGDSSHCSNASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMD 221
Q +++ E D S SN+EA K +D+ + ++ ++
Sbjct: 117 QHLDSHRNGETKADDS--------SNKEAA----EEKPEEDNDYHRSDEQVSICLE---- 160
Query: 222 GASEIELVFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALEELRSKGESNQM 281
K + ++I+ S ATV HL K++A +L L N++
Sbjct: 161 -------------CNSSKLRGLKRKWIRCSAQATVLHLKKFIAKKLNLSSF------NEL 201
Query: 282 NLDTASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNK-PMELYYAP 331
++ E +L +L+ V W+ K P+ L+Y P
Sbjct: 202 DILCNEE---------------ILGKDHTLKFVVVTRWRFKKAPLLLHYRP 237
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Query: 49 LMCPICLDMLKNTMTTKECLHRFCADCIITAL--RSGNKECPTCRKKLVSKRSLRPDPNF 106
L CPICL+++K ++TK C H FC C++ L + G +CP C K ++KRSL+ F
Sbjct: 22 LECPICLELIKEPVSTK-CDHIFCKFCMLKLLNQKKGPSQCPLC-KNDITKRSLQESTRF 79
Query: 107 DALISKIYPSRDEYEAHQERVLARINKHN----NQQALSHSIEEGLKIQAM---NRLQRG 159
L+ ++ ++ + L N +N + H +E IQ+M NR +R
Sbjct: 80 SQLVEELLKIICAFQL--DTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL 137
Query: 160 KKQQIENGSGAEDNGDSSHCSNAST 184
+ + EN S ++ S SN T
Sbjct: 138 LQSEPENPS-LQETSLSVQLSNLGT 161
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Query: 49 LMCPICLDMLKNTMTTKECLHRFCADCIITAL--RSGNKECPTCRKKLVSKRSLRPDPNF 106
L CPICL+++K ++TK C H FC C++ L + G +CP C K ++KRSL+ F
Sbjct: 22 LECPICLELIKEPVSTK-CDHIFCKFCMLKLLNQKKGPSQCPLC-KNDITKRSLQESTRF 79
Query: 107 DALISKIYPSRDEYEAHQERVLARINKHN----NQQALSHSIEEGLKIQAM---NRLQRG 159
L+ ++ ++ + L N +N + H +E IQ+M NR +R
Sbjct: 80 SQLVEELLKIICAFQL--DTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL 137
Query: 160 KKQQIENGSGAEDNGDSSHCSNAST 184
+ + EN S ++ S SN T
Sbjct: 138 LQSEPENPS-LQETSLSVQLSNLGT 161
>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
Length = 759
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Query: 49 LMCPICLDMLKNTMTTKECLHRFCADCIITAL--RSGNKECPTCRKKLVSKRSLRPDPNF 106
L CPICL+++K ++TK C H FC C++ L + G +CP C K ++KRSL+ F
Sbjct: 22 LECPICLELIKEPVSTK-CDHIFCKFCMLKLLNQKKGPSQCPLC-KNDITKRSLQESTRF 79
Query: 107 DALISKIYPSRDEYEAHQERVLARINKHN----NQQALSHSIEEGLKIQAM---NRLQRG 159
L+ ++ ++ + L N +N + H +E IQ+M NR +R
Sbjct: 80 SQLVEELLKIICAFQL--DTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL 137
Query: 160 KKQQIENGSGAEDNGDSSHCSNAST 184
+ + EN S ++ S SN T
Sbjct: 138 LQSEPENPS-LQETSLSVQLSNLGT 161
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Query: 49 LMCPICLDMLKNTMTTKECLHRFCADCIITAL--RSGNKECPTCRKKLVSKRSLRPDPNF 106
L CPICL+++K ++TK C H FC C++ L + G +CP C K ++KRSL+ F
Sbjct: 22 LECPICLELIKEPVSTK-CDHIFCKFCMLKLLNQKKGPSQCPLC-KNDITKRSLQESTRF 79
Query: 107 DALISKIYPSRDEYEAHQERVLARINKHN----NQQALSHSIEEGLKIQAM---NRLQRG 159
L+ ++ ++ + L N +N + H +E IQ+M NR +R
Sbjct: 80 SQLVEELLKIICAFQL--DTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL 137
Query: 160 KKQQIENGSGAEDNGDSSHCSNAST 184
+ + EN S ++ S SN T
Sbjct: 138 LQSEPENPS-LQETSLSVQLSNLGT 161
>gi|21361539 ring finger protein 138 isoform 1 [Homo sapiens]
Length = 245
Score = 53.5 bits (127), Expect = 3e-07
Identities = 20/60 (33%), Positives = 30/60 (50%)
Query: 48 ELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFD 107
+ CP+C ++LK + T C H FC C +TA+R CP CR + + P+ D
Sbjct: 15 DFYCPVCQEVLKTPVRTTACQHVFCRKCFLTAMRESGAHCPLCRGNVTRRERACPERALD 74
>gi|6005964 ring finger protein 110 [Homo sapiens]
Length = 344
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/152 (28%), Positives = 64/152 (42%), Gaps = 28/152 (18%)
Query: 45 LHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKR---SLR 101
L+ LMC +C + T ECLH FC CI+ L + NK CP C ++ R S+R
Sbjct: 12 LNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLET-NKYCPMCDVQVHKTRPLLSIR 70
Query: 102 PDPNFDALISKIYPS---------RDEYEAHQERVLARINKHNNQQ----------ALSH 142
D ++ K+ P RD Y A+ L + +N+ ALS
Sbjct: 71 SDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYP---LTEVPNGSNEDRGEVLEQEKGALSD 127
Query: 143 SIEEGLKIQAMN--RLQRGKKQQIENGSGAED 172
L I+ R + KK +ENG G ++
Sbjct: 128 DEIVSLSIEFYEGARDRDEKKGPLENGDGDKE 159
>gi|33300663 polycomb group ring finger 5 [Homo sapiens]
Length = 256
Score = 50.4 bits (119), Expect = 2e-06
Identities = 64/286 (22%), Positives = 96/286 (33%), Gaps = 53/286 (18%)
Query: 49 LMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDA 108
+ C IC L T ECLH FC CI+ N +CP C
Sbjct: 16 ITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSN-DCPRCGN---------------- 58
Query: 109 LISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGS 168
+ H+ L + N + + + GL+ Q + R K+ +
Sbjct: 59 ------------QVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQEN 106
Query: 169 GAEDNGDSSHCSNASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIEL 228
G +D S A E G N+ DD + A+ +D + + +
Sbjct: 107 GQDDT------SKADKPKVDEEGDENE-----DDKDYHRSDPQIAICLDCLRNNGQSGDN 155
Query: 229 VFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALE---ELRSKGESNQMNLDT 285
V + LM+K +I+ S TV + K+L+++L L EL M D
Sbjct: 156 VVK---GLMKK-------FIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDH 205
Query: 286 ASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAP 331
E Y F LN S S + + PM L Y P
Sbjct: 206 TMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVLQYRP 251
>gi|109240538 polycomb group ring finger 1 [Homo sapiens]
Length = 259
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/116 (27%), Positives = 57/116 (49%), Gaps = 11/116 (9%)
Query: 37 EIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVS 96
E+ V + L+ ++C +C + T ECLH FC CI+ L++ +K CP C K+
Sbjct: 33 EVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQT-SKYCPMCNIKIHE 91
Query: 97 KR---SLRPDPNFDALISKIYPSRDEYEA------HQERVLARINKHNNQQ-ALSH 142
+ +L+ D ++ K+ P + E +Q R L R+ + ++ ALS+
Sbjct: 92 TQPLLNLKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPTGEEPALSN 147
>gi|15208660 tripartite motif protein 21 [Homo sapiens]
Length = 475
Score = 50.1 bits (118), Expect = 3e-06
Identities = 23/66 (34%), Positives = 37/66 (56%), Gaps = 2/66 (3%)
Query: 48 ELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFD 107
E+ CPICLD ++ EC H FC +CI + G CP CR++ + K +LRP+
Sbjct: 13 EVTCPICLDPFVEPVSI-ECGHSFCQECISQVGKGGGSVCPVCRQRFLLK-NLRPNRQLA 70
Query: 108 ALISKI 113
+++ +
Sbjct: 71 NMVNNL 76
>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
Length = 539
Score = 48.1 bits (113), Expect = 1e-05
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 9/123 (7%)
Query: 43 RSLHSELMCPICLDMLKNTMTTKECLHRFCADCI--ITALRSGNKECPTCRKKLVSKRSL 100
RSL E+ C ICLD L++ +T +C H FC C + + CP C KK K ++
Sbjct: 8 RSLEEEVTCSICLDYLRDPVTI-DCGHVFCRSCTTDVRPISGSRPVCPLC-KKPFKKENI 65
Query: 101 RPDPNFDALIS-----KIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNR 155
RP +L+ K+ R E +E+ A++ + + ++ + ++G + M R
Sbjct: 66 RPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCEDDGKLLCVMCR 125
Query: 156 LQR 158
R
Sbjct: 126 ESR 128
>gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]
Length = 326
Score = 47.8 bits (112), Expect = 1e-05
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 13/91 (14%)
Query: 45 LHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKR---SLR 101
L+ LMC +C + T ECLH FC CI+ L + +K CP C ++ R ++R
Sbjct: 12 LNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLET-SKYCPICDVQVHKTRPLLNIR 70
Query: 102 PDPNFDALISKIYPS---------RDEYEAH 123
D ++ K+ P RD Y AH
Sbjct: 71 SDKTLQDIVYKLVPGLFKNEMKRRRDFYAAH 101
>gi|4506561 ring finger protein 4 [Homo sapiens]
Length = 190
Score = 47.4 bits (111), Expect = 2e-05
Identities = 28/84 (33%), Positives = 45/84 (53%), Gaps = 11/84 (13%)
Query: 21 LYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLD----MLKN--TMTTKECLHRFCAD 74
+Y TP+ A +G + + CPIC+D +++N + + EC H FC+
Sbjct: 106 VYVTTHTPRNARDEG----ATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQ 161
Query: 75 CIITALRSGNKECPTCRKKLVSKR 98
C+ +L++ N CPTCRKK+ KR
Sbjct: 162 CLRDSLKNAN-TCPTCRKKINHKR 184
>gi|62865604 tripartite motif protein 31 [Homo sapiens]
Length = 425
Score = 47.0 bits (110), Expect = 2e-05
Identities = 28/71 (39%), Positives = 39/71 (54%), Gaps = 4/71 (5%)
Query: 45 LHSELMCPICLDMLKNTMTTKECLHRFCADCI--ITALRSGNKECPTCRKKLVSKRSLRP 102
L E++CPICLD+L+ +T +C H FC CI I G +CP C K V K ++R
Sbjct: 10 LQEEVICPICLDILQKPVTI-DCGHNFCLKCITQIGETSCGFFKCPLC-KTSVRKNAIRF 67
Query: 103 DPNFDALISKI 113
+ L+ KI
Sbjct: 68 NSLLRNLVEKI 78
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 47.0 bits (110), Expect = 2e-05
Identities = 37/151 (24%), Positives = 64/151 (42%), Gaps = 34/151 (22%)
Query: 47 SELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCR-----------KKLV 95
++ +CPIC DM++ TK C H FC CI +L N+ CP C LV
Sbjct: 132 NDFVCPICFDMIEEAYMTK-CGHSFCYKCIHQSLEDNNR-CPKCNYVVDNIDHLYPNFLV 189
Query: 96 SKRSLRPDPNFDALISKIYPSRDEYEAHQERV-------------LARIN--------KH 134
++ L+ F+ K+ S H+ ++ LA +N K
Sbjct: 190 NELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKK 249
Query: 135 NNQQALSHSIEEGLKIQAMNRLQRGKKQQIE 165
+A SH+ + + ++ + +R K++Q+E
Sbjct: 250 KQLEAESHAAQLQILMEFLKVARRNKREQLE 280
>gi|30425428 deltex homolog 3 [Homo sapiens]
Length = 347
Score = 46.6 bits (109), Expect = 3e-05
Identities = 28/77 (36%), Positives = 39/77 (50%), Gaps = 6/77 (7%)
Query: 48 ELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFD 107
E CPICL ++N T ++C H FC CI AL+ K CP C + +P N
Sbjct: 161 ESTCPICLGEIQNAKTLEKCRHSFCEGCITRALQV-KKACPMCGRFYGQLVGNQPQ-NGR 218
Query: 108 ALISK----IYPSRDEY 120
L+SK + PS ++Y
Sbjct: 219 MLVSKDATLLLPSYEKY 235
>gi|169160953 PREDICTED: hypothetical LOC644006 [Homo sapiens]
Length = 190
Score = 46.2 bits (108), Expect = 4e-05
Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 7/54 (12%)
Query: 51 CPICLDML------KNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKR 98
CPIC+D + + + EC H FC+ C+ +L++ N CPTCRKK+ K+
Sbjct: 132 CPICMDRYSEIVQNRRLIVSTECGHVFCSQCLRDSLKNAN-TCPTCRKKINHKQ 184
>gi|239747623 PREDICTED: hypothetical protein XP_002347917 [Homo
sapiens]
Length = 190
Score = 46.2 bits (108), Expect = 4e-05
Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 7/54 (12%)
Query: 51 CPICLDML------KNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKR 98
CPIC+D + + + EC H FC+ C+ +L++ N CPTCRKK+ K+
Sbjct: 132 CPICMDRYSEIVQNRRLIVSTECGHVFCSQCLRDSLKNAN-TCPTCRKKINHKQ 184
>gi|88943822 PREDICTED: hypothetical protein LOC644006 [Homo
sapiens]
Length = 190
Score = 46.2 bits (108), Expect = 4e-05
Identities = 21/54 (38%), Positives = 32/54 (59%), Gaps = 7/54 (12%)
Query: 51 CPICLDML------KNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKR 98
CPIC+D + + + EC H FC+ C+ +L++ N CPTCRKK+ K+
Sbjct: 132 CPICMDRYSEIVQNRRLIVSTECGHVFCSQCLRDSLKNAN-TCPTCRKKINHKQ 184
>gi|60099474 tripartite motif-containing 61 [Homo sapiens]
Length = 209
Score = 46.2 bits (108), Expect = 4e-05
Identities = 37/119 (31%), Positives = 55/119 (46%), Gaps = 9/119 (7%)
Query: 36 LEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRS--GNKECPTCRKK 93
+E V + L +E CPICLD LK+ +T C H FC CII + + + CP C
Sbjct: 1 MEFVTALADLRAEASCPICLDYLKDPVTI-SCGHNFCLSCIIMSWKDLHDSFPCPFCH-F 58
Query: 94 LVSKRSLRPDPNFDAL--ISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKI 150
+R +P +L I+K R + QE KHN Q L+ ++ L++
Sbjct: 59 CCPERKFISNPQLGSLTEIAKQLQIRSKKRKRQEEKHV-CKKHN--QVLTFFCQKDLEL 114
>gi|22027630 TNF receptor-associated factor 6 [Homo sapiens]
Length = 522
Score = 45.8 bits (107), Expect = 5e-05
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 35 GLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKL 94
G ++ P L S+ CPICL L+ + T C HRFC CII ++R +CP ++
Sbjct: 55 GYDVEFDP-PLESKYECPICLMALREAVQTP-CGHRFCKACIIKSIRDAGHKCPV-DNEI 111
Query: 95 VSKRSLRPD 103
+ + L PD
Sbjct: 112 LLENQLFPD 120
>gi|4759254 TNF receptor-associated factor 6 [Homo sapiens]
Length = 522
Score = 45.8 bits (107), Expect = 5e-05
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 35 GLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKL 94
G ++ P L S+ CPICL L+ + T C HRFC CII ++R +CP ++
Sbjct: 55 GYDVEFDP-PLESKYECPICLMALREAVQTP-CGHRFCKACIIKSIRDAGHKCPV-DNEI 111
Query: 95 VSKRSLRPD 103
+ + L PD
Sbjct: 112 LLENQLFPD 120
>gi|23312364 ubiquitin-like with PHD and ring finger domains 2 [Homo
sapiens]
Length = 802
Score = 45.1 bits (105), Expect = 9e-05
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 43 RSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRP 102
+ L MC C +++ +TT EC H C DC+ + ++ CP CR L + P
Sbjct: 725 KKLEQSFMCVCCQELVYQPVTT-ECFHNVCKDCLQRSFKAQVFSCPACRHDLGQNYIMIP 783
Query: 103 DPNFDALISKIYP 115
+ L+ +P
Sbjct: 784 NEILQTLLDLFFP 796
>gi|37595555 ring finger protein 125 [Homo sapiens]
Length = 232
Score = 45.1 bits (105), Expect = 9e-05
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 28 PQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKEC 87
P A LE P + C +CL++L + T+ C H FC CI T+L++ C
Sbjct: 14 PASATARALERRRDPELPVTSFDCAVCLEVLHQPVRTR-CGHVFCRSCIATSLKNNKWTC 72
Query: 88 PTCRKKLVSK 97
P CR L S+
Sbjct: 73 PYCRAYLPSE 82
>gi|239048909 checkpoint with forkhead and ring finger domains
isoform 5 [Homo sapiens]
Length = 572
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 9 GTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECL 68
G L +L + + +R Q D P + L C IC D+L + ++ + C+
Sbjct: 170 GDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCM 229
Query: 69 HRFCADCIITALRSGNKECPTCR 91
H FCA C + + CPTCR
Sbjct: 230 HTFCAAC-YSGWMERSSLCPTCR 251
>gi|239048905 checkpoint with forkhead and ring finger domains
isoform 3 [Homo sapiens]
Length = 652
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 9 GTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECL 68
G L +L + + +R Q D P + L C IC D+L + ++ + C+
Sbjct: 250 GDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCM 309
Query: 69 HRFCADCIITALRSGNKECPTCR 91
H FCA C + + CPTCR
Sbjct: 310 HTFCAAC-YSGWMERSSLCPTCR 331
>gi|239048862 checkpoint with forkhead and ring finger domains
isoform 2 [Homo sapiens]
Length = 663
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 9 GTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECL 68
G L +L + + +R Q D P + L C IC D+L + ++ + C+
Sbjct: 262 GDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCM 321
Query: 69 HRFCADCIITALRSGNKECPTCR 91
H FCA C + + CPTCR
Sbjct: 322 HTFCAAC-YSGWMERSSLCPTCR 343
>gi|239048792 checkpoint with forkhead and ring finger domains
isoform 1 [Homo sapiens]
Length = 664
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 9 GTQPLSKTWELSLYELQRTPQEAITDGLEIVVSPRSLHSELMCPICLDMLKNTMTTKECL 68
G L +L + + +R Q D P + L C IC D+L + ++ + C+
Sbjct: 262 GDGDLDLNGQLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCM 321
Query: 69 HRFCADCIITALRSGNKECPTCR 91
H FCA C + + CPTCR
Sbjct: 322 HTFCAAC-YSGWMERSSLCPTCR 343
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.126 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,401,901
Number of Sequences: 37866
Number of extensions: 516103
Number of successful extensions: 1885
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 1669
Number of HSP's gapped (non-prelim): 352
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.