Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 5902034
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
(501 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5902034 periodic tryptophan protein 1 [Homo sapiens] 1021 0.0
gi|14149987 WD repeat domain 24 [Homo sapiens] 76 8e-14
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 73 7e-13
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 67 3e-11
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 67 3e-11
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 67 3e-11
gi|16554629 WD repeat domain 5 [Homo sapiens] 67 3e-11
gi|16554627 WD repeat domain 5 [Homo sapiens] 67 3e-11
gi|32189425 WD repeat domain 69 [Homo sapiens] 67 3e-11
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 66 6e-11
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 65 1e-10
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 65 1e-10
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 65 1e-10
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 63 7e-10
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 63 7e-10
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 63 7e-10
gi|13376840 WD repeat domain 61 [Homo sapiens] 63 7e-10
gi|14150171 THO complex 3 [Homo sapiens] 63 7e-10
gi|217330644 WD repeat domain 12 protein [Homo sapiens] 62 1e-09
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 62 2e-09
gi|23199987 WD repeat domain 5B [Homo sapiens] 62 2e-09
gi|4502477 beta-transducin repeat containing protein isoform 2 [... 61 3e-09
gi|16117783 beta-transducin repeat containing protein isoform 1 ... 61 3e-09
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 61 3e-09
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 61 3e-09
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 61 3e-09
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 61 3e-09
gi|65787364 coronin, actin binding protein, 1B [Homo sapiens] 60 6e-09
gi|14149734 coronin, actin binding protein, 1B [Homo sapiens] 60 6e-09
gi|229892270 WD repeats and SOF1 domain containing [Homo sapiens] 59 8e-09
>gi|5902034 periodic tryptophan protein 1 [Homo sapiens]
Length = 501
Score = 1021 bits (2640), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 1 MNRSRQVTCVAWVRCGVAKETPDKVELSKEEVKRLIAEAKEKLQEEGGGSDEEETGSPSE 60
MNRSRQVTCVAWVRCGVAKETPDKVELSKEEVKRLIAEAKEKLQEEGGGSDEEETGSPSE
Sbjct: 1 MNRSRQVTCVAWVRCGVAKETPDKVELSKEEVKRLIAEAKEKLQEEGGGSDEEETGSPSE 60
Query: 61 DGMQSARTQARPREPLEDGDPEDDRTLDDDELAEYDLDKYDEEGDPDAETLGESLLGLTV 120
DGMQSARTQARPREPLEDGDPEDDRTLDDDELAEYDLDKYDEEGDPDAETLGESLLGLTV
Sbjct: 61 DGMQSARTQARPREPLEDGDPEDDRTLDDDELAEYDLDKYDEEGDPDAETLGESLLGLTV 120
Query: 121 YGSNDQDPYVTLKDTEQYEREDFLIKPSDNLIVCGRAEQDQCNLEVHVYNQEEDSFYVHH 180
YGSNDQDPYVTLKDTEQYEREDFLIKPSDNLIVCGRAEQDQCNLEVHVYNQEEDSFYVHH
Sbjct: 121 YGSNDQDPYVTLKDTEQYEREDFLIKPSDNLIVCGRAEQDQCNLEVHVYNQEEDSFYVHH 180
Query: 181 DILLSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSK 240
DILLSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSK
Sbjct: 181 DILLSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSK 240
Query: 241 KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTD 300
KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTD
Sbjct: 241 KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTD 300
Query: 301 KVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLA 360
KVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLA
Sbjct: 301 KVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLA 360
Query: 361 STDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRP 420
STDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRP
Sbjct: 361 STDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRP 420
Query: 421 SLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEAFGRRERLVLGS 480
SLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEAFGRRERLVLGS
Sbjct: 421 SLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEAFGRRERLVLGS 480
Query: 481 ARNSSISGPFGSRSSDTPMES 501
ARNSSISGPFGSRSSDTPMES
Sbjct: 481 ARNSSISGPFGSRSSDTPMES 501
>gi|14149987 WD repeat domain 24 [Homo sapiens]
Length = 790
Score = 75.9 bits (185), Expect = 8e-14
Identities = 57/173 (32%), Positives = 85/173 (49%), Gaps = 14/173 (8%)
Query: 261 DLSWNKLIRNVLASASADNTVILWDMSLGKPAAS-----LAVHTDKVQTLQFHPFEAQTL 315
D+ W+++ N+LA+A+ + V+ W+ LG+P+ + H V + FHP EA L
Sbjct: 79 DVVWHQMDENLLATAATNGVVVTWN--LGRPSRNKQDQLFTEHKRTVNKVCFHPTEAHVL 136
Query: 316 ISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFL--AST-DDGFVYNLDA 372
+SGS D + +D R D + FSGQ E V FS + AST ++G V D
Sbjct: 137 LSGSQDGFMKCFDLRRKDS---VSTFSGQSESVRDVQFSIRDYFTFASTFENGNVQLWDI 193
Query: 373 RS-DKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVH 424
R D+ AHN + D + +G L T DK VK+WD+ R +H
Sbjct: 194 RRPDRCERMFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVWDMTTHRAKEMH 246
Score = 32.3 bits (72), Expect = 1.0
Identities = 45/200 (22%), Positives = 73/200 (36%), Gaps = 29/200 (14%)
Query: 217 IEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASAS 276
+++WD+ D E +FT H V W+ R LA+
Sbjct: 188 VQLWDIRRPDRCERMFT--------------------AHNGPVFCCDWHPEDRGWLATGG 227
Query: 277 ADNTVILWDMSLGKPAASLAVHT-DKVQTLQFHPFEAQTLISGS--YDKSVALYDCRSPD 333
D V +WDM+ + V T V +++ P L + S D ++ ++D R P
Sbjct: 228 RDKMVKVWDMTTHRAKEMHCVQTIASVARVKWRPECRHHLATCSMMVDHNIYVWDVRRPF 287
Query: 334 ESHRMWRFSGQIER-VTWNHFSPCHFL--ASTDDGFVYNLDARSDKPIFTLNAHNDEISG 390
M+ + + W H FL S D +L + +P+ N G
Sbjct: 288 VPAAMFEEHRDVTTGIAWRHPHDPSFLLSGSKDSSLCQHLFRDASQPVERANPEG-LCYG 346
Query: 391 L--DLSSQIKGCLVTASADK 408
L DL+ K LV A + +
Sbjct: 347 LFGDLAFAAKESLVAAESGR 366
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 72.8 bits (177), Expect = 7e-13
Identities = 71/258 (27%), Positives = 123/258 (47%), Gaps = 30/258 (11%)
Query: 250 SSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHP 309
++ +GH+ AV++L +N ++L SAS D TV +WD G+ L HT V +
Sbjct: 103 ATLKGHSGAVMELHYNT-DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPAR 161
Query: 310 FEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYN 369
Q + +GS D +V L+D R + + ++ + Q+ VT+N S ++ D +
Sbjct: 162 RGPQLVCTGSDDGTVKLWDIRK-KAAIQTFQNTYQVLAVTFNDTSD-QIISGGIDNDIKV 219
Query: 370 LDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMK 429
D R +K +T+ H D ++GL LSS+ L++ + D V++WD+ RP R +K
Sbjct: 220 WDLRQNKLTYTMRGHADSVTGLSLSSE-GSYLLSNAMDNTVRVWDV---RPFAPKERCVK 275
Query: 430 M----------GVLFCSSCCPDLPFIYAFGGQKEGLRVWDIST----------VSSVNE- 468
+ +L C S PD I A G + VWD ++ S+NE
Sbjct: 276 IFQGNVHNFEKNLLRC-SWSPDGSKI-AAGSADRFVYVWDTTSRRILYKLPGHAGSINEV 333
Query: 469 AFGRRERLVLGSARNSSI 486
AF E +++ ++ + +
Sbjct: 334 AFHPDEPIIISASSDKRL 351
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 67.4 bits (163), Expect = 3e-11
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 18/180 (10%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDM---SLGKPAASLAVHTDKVQTLQFHPF 310
GHT V D+SW+ L ++ S + D +++WD + KP+ S+ HT +V L F+P+
Sbjct: 190 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 249
Query: 311 EAQTLISGSYDKSVALYDCRSPD-ESHRMWRFSGQIERVTWNHFSPCHFLASTDDG--FV 367
L +GS DK+VAL+D R+ + H +I +V W+ + +S D V
Sbjct: 250 SEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNV 309
Query: 368 YNL----------DARSDKP--IFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
++L DA P +F H +IS + + + S D +++W +
Sbjct: 310 WDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 369
Score = 65.5 bits (158), Expect = 1e-10
Identities = 56/213 (26%), Positives = 86/213 (40%), Gaps = 40/213 (18%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH LSWN + L SAS D+T+ LWD+S + +A+
Sbjct: 140 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVV--------------DAK 185
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
T+ +G + +E V+W+ F + DD + D R
Sbjct: 186 TIFTGH----------------------TAVVEDVSWHLLHESLFGSVADDQKLMIWDTR 223
Query: 374 SD---KPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKM 430
S+ KP +++AH E++ L + + L T SADK V +WD+ + L HS +
Sbjct: 224 SNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL-HSFESHK 282
Query: 431 GVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTV 463
+F P I A G L VWD+S +
Sbjct: 283 DEIFQVQWSPHNETILASSGTDRRLNVWDLSKI 315
Score = 48.9 bits (115), Expect = 1e-05
Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 241 KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDM-SLGKPAASLAVHT 299
+ K S S + HT V LS+N +LA+ SAD TV LWD+ +L S H
Sbjct: 223 RSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHK 282
Query: 300 DKVQTLQFHPFEAQTLISGSYDKSVALYD 328
D++ +Q+ P L S D+ + ++D
Sbjct: 283 DEIFQVQWSPHNETILASSGTDRRLNVWD 311
Score = 37.4 bits (85), Expect = 0.032
Identities = 34/158 (21%), Positives = 62/158 (39%), Gaps = 38/158 (24%)
Query: 184 LSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKK 243
+ A+ V L+F+P + +A G+ + +WDL +
Sbjct: 234 VDAHTAEVNCLSFNPYSEF----ILATGSADKTVALWDL--------------------R 269
Query: 244 KKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMS-LGK----------PA 292
K S E H D + + W+ +LAS+ D + +WD+S +G+ P
Sbjct: 270 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 329
Query: 293 ASLAV---HTDKVQTLQFHPFEAQTLISGSYDKSVALY 327
L + HT K+ ++P E + S S D + ++
Sbjct: 330 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 367
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 67.4 bits (163), Expect = 3e-11
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 18/180 (10%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDM---SLGKPAASLAVHTDKVQTLQFHPF 310
GHT V D+SW+ L ++ S + D +++WD + KP+ S+ HT +V L F+P+
Sbjct: 224 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 283
Query: 311 EAQTLISGSYDKSVALYDCRSPD-ESHRMWRFSGQIERVTWNHFSPCHFLASTDDG--FV 367
L +GS DK+VAL+D R+ + H +I +V W+ + +S D V
Sbjct: 284 SEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNV 343
Query: 368 YNL----------DARSDKP--IFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
++L DA P +F H +IS + + + S D +++W +
Sbjct: 344 WDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 403
Score = 65.5 bits (158), Expect = 1e-10
Identities = 56/213 (26%), Positives = 86/213 (40%), Gaps = 40/213 (18%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH LSWN + L SAS D+T+ LWD+S + +A+
Sbjct: 174 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVV--------------DAK 219
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
T+ +G + +E V+W+ F + DD + D R
Sbjct: 220 TIFTGH----------------------TAVVEDVSWHLLHESLFGSVADDQKLMIWDTR 257
Query: 374 SD---KPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKM 430
S+ KP +++AH E++ L + + L T SADK V +WD+ + L HS +
Sbjct: 258 SNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL-HSFESHK 316
Query: 431 GVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTV 463
+F P I A G L VWD+S +
Sbjct: 317 DEIFQVQWSPHNETILASSGTDRRLNVWDLSKI 349
Score = 48.9 bits (115), Expect = 1e-05
Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 241 KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDM-SLGKPAASLAVHT 299
+ K S S + HT V LS+N +LA+ SAD TV LWD+ +L S H
Sbjct: 257 RSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHK 316
Query: 300 DKVQTLQFHPFEAQTLISGSYDKSVALYD 328
D++ +Q+ P L S D+ + ++D
Sbjct: 317 DEIFQVQWSPHNETILASSGTDRRLNVWD 345
Score = 37.4 bits (85), Expect = 0.032
Identities = 34/158 (21%), Positives = 62/158 (39%), Gaps = 38/158 (24%)
Query: 184 LSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKK 243
+ A+ V L+F+P + +A G+ + +WDL +
Sbjct: 268 VDAHTAEVNCLSFNPYSEF----ILATGSADKTVALWDL--------------------R 303
Query: 244 KKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMS-LGK----------PA 292
K S E H D + + W+ +LAS+ D + +WD+S +G+ P
Sbjct: 304 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 363
Query: 293 ASLAV---HTDKVQTLQFHPFEAQTLISGSYDKSVALY 327
L + HT K+ ++P E + S S D + ++
Sbjct: 364 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 401
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 67.4 bits (163), Expect = 3e-11
Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 18/180 (10%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDM---SLGKPAASLAVHTDKVQTLQFHPF 310
GHT V D+SW+ L ++ S + D +++WD + KP+ S+ HT +V L F+P+
Sbjct: 225 GHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSVDAHTAEVNCLSFNPY 284
Query: 311 EAQTLISGSYDKSVALYDCRSPD-ESHRMWRFSGQIERVTWNHFSPCHFLASTDDG--FV 367
L +GS DK+VAL+D R+ + H +I +V W+ + +S D V
Sbjct: 285 SEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNV 344
Query: 368 YNL----------DARSDKP--IFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
++L DA P +F H +IS + + + S D +++W +
Sbjct: 345 WDLSKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 404
Score = 65.5 bits (158), Expect = 1e-10
Identities = 56/213 (26%), Positives = 86/213 (40%), Gaps = 40/213 (18%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH LSWN + L SAS D+T+ LWD+S + +A+
Sbjct: 175 GHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVV--------------DAK 220
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
T+ +G + +E V+W+ F + DD + D R
Sbjct: 221 TIFTGH----------------------TAVVEDVSWHLLHESLFGSVADDQKLMIWDTR 258
Query: 374 SD---KPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKM 430
S+ KP +++AH E++ L + + L T SADK V +WD+ + L HS +
Sbjct: 259 SNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL-HSFESHK 317
Query: 431 GVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTV 463
+F P I A G L VWD+S +
Sbjct: 318 DEIFQVQWSPHNETILASSGTDRRLNVWDLSKI 350
Score = 48.9 bits (115), Expect = 1e-05
Identities = 29/89 (32%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 241 KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDM-SLGKPAASLAVHT 299
+ K S S + HT V LS+N +LA+ SAD TV LWD+ +L S H
Sbjct: 258 RSNNTSKPSHSVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHK 317
Query: 300 DKVQTLQFHPFEAQTLISGSYDKSVALYD 328
D++ +Q+ P L S D+ + ++D
Sbjct: 318 DEIFQVQWSPHNETILASSGTDRRLNVWD 346
Score = 37.4 bits (85), Expect = 0.032
Identities = 34/158 (21%), Positives = 62/158 (39%), Gaps = 38/158 (24%)
Query: 184 LSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKK 243
+ A+ V L+F+P + +A G+ + +WDL +
Sbjct: 269 VDAHTAEVNCLSFNPYSEF----ILATGSADKTVALWDL--------------------R 304
Query: 244 KKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMS-LGK----------PA 292
K S E H D + + W+ +LAS+ D + +WD+S +G+ P
Sbjct: 305 NLKLKLHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPP 364
Query: 293 ASLAV---HTDKVQTLQFHPFEAQTLISGSYDKSVALY 327
L + HT K+ ++P E + S S D + ++
Sbjct: 365 ELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVW 402
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 67.4 bits (163), Expect = 3e-11
Identities = 49/170 (28%), Positives = 88/170 (51%), Gaps = 5/170 (2%)
Query: 246 GKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTL 305
GK + GH + D++W+ N+L SAS D T+ +WD+S GK +L H++ V
Sbjct: 77 GKFEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCC 135
Query: 306 QFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDG 365
F+P ++ ++SGS+D+SV ++D ++ + S + V +N ++S+ DG
Sbjct: 136 NFNP-QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSL-IVSSSYDG 193
Query: 366 FVYNLDARSDKPIFTL-NAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
D S + + TL + N +S + S K ++ A+ D +K+WD
Sbjct: 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGK-YILAATLDNTLKLWD 242
Score = 46.2 bits (108), Expect = 7e-05
Identities = 42/163 (25%), Positives = 78/163 (47%), Gaps = 8/163 (4%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GHT AV + ++ LAS+SAD + +W GK +++ H + + + ++
Sbjct: 43 GHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS-DSN 100
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCH--FLASTDDGFVYNLD 371
L+S S DK++ ++D S + G V +F+P ++ + D V D
Sbjct: 101 LLVSASDDKTLKIWDVSS---GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Query: 372 ARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
++ K + TL AH+D +S + + +V++S D +IWD
Sbjct: 158 VKTGKCLKTLPAHSDPVSAVHFNRD-GSLIVSSSYDGLCRIWD 199
Score = 33.1 bits (74), Expect = 0.61
Identities = 34/146 (23%), Positives = 57/146 (39%), Gaps = 35/146 (23%)
Query: 191 VEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSS 250
V ++ F P+ G YI + +++WD KGK
Sbjct: 217 VSFVKFSPN-----GKYILAATLDNTLKLWDYS---------------------KGKCLK 250
Query: 251 SAEGHTDAVLDLSWNKLIRNV--LASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFH 308
+ GH + + N + + S S DN V +W++ + L HTD V + H
Sbjct: 251 TYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACH 310
Query: 309 PFEAQTLISGS---YDKSVALY--DC 329
P E +I+ + DK++ L+ DC
Sbjct: 311 PTE--NIIASAALENDKTIKLWKSDC 334
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 67.4 bits (163), Expect = 3e-11
Identities = 49/170 (28%), Positives = 88/170 (51%), Gaps = 5/170 (2%)
Query: 246 GKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTL 305
GK + GH + D++W+ N+L SAS D T+ +WD+S GK +L H++ V
Sbjct: 77 GKFEKTISGHKLGISDVAWSS-DSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCC 135
Query: 306 QFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDG 365
F+P ++ ++SGS+D+SV ++D ++ + S + V +N ++S+ DG
Sbjct: 136 NFNP-QSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSL-IVSSSYDG 193
Query: 366 FVYNLDARSDKPIFTL-NAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
D S + + TL + N +S + S K ++ A+ D +K+WD
Sbjct: 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGK-YILAATLDNTLKLWD 242
Score = 46.2 bits (108), Expect = 7e-05
Identities = 42/163 (25%), Positives = 78/163 (47%), Gaps = 8/163 (4%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GHT AV + ++ LAS+SAD + +W GK +++ H + + + ++
Sbjct: 43 GHTKAVSSVKFSPN-GEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSS-DSN 100
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCH--FLASTDDGFVYNLD 371
L+S S DK++ ++D S + G V +F+P ++ + D V D
Sbjct: 101 LLVSASDDKTLKIWDVSS---GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWD 157
Query: 372 ARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
++ K + TL AH+D +S + + +V++S D +IWD
Sbjct: 158 VKTGKCLKTLPAHSDPVSAVHFNRD-GSLIVSSSYDGLCRIWD 199
Score = 33.1 bits (74), Expect = 0.61
Identities = 34/146 (23%), Positives = 57/146 (39%), Gaps = 35/146 (23%)
Query: 191 VEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSS 250
V ++ F P+ G YI + +++WD KGK
Sbjct: 217 VSFVKFSPN-----GKYILAATLDNTLKLWDYS---------------------KGKCLK 250
Query: 251 SAEGHTDAVLDLSWNKLIRNV--LASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFH 308
+ GH + + N + + S S DN V +W++ + L HTD V + H
Sbjct: 251 TYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACH 310
Query: 309 PFEAQTLISGS---YDKSVALY--DC 329
P E +I+ + DK++ L+ DC
Sbjct: 311 PTE--NIIASAALENDKTIKLWKSDC 334
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 67.4 bits (163), Expect = 3e-11
Identities = 61/273 (22%), Positives = 117/273 (42%), Gaps = 34/273 (12%)
Query: 145 IKPSDNLIVCGRAEQDQC---NLEVHVYNQEEDSFYVHHDILLSAYPLSVEWLNFDPSPD 201
I+ ++ L+ R EQ + L+ + +FY+ + PL+ LN
Sbjct: 48 IQKAEPLLTASRTEQVKLLIQRLQEKLGQNSNHTFYLFKVLKAHILPLTNVALN------ 101
Query: 202 DSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLD 261
+G+ G+ ++WD G++ ++ EGH + V
Sbjct: 102 -KSGSCFITGSYDRTCKLWDT---------------------ASGEELNTLEGHRNVVYA 139
Query: 262 LSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYD 321
+++N + +A+ S D T LW + GK + HT ++ L F+P ++ + +GS D
Sbjct: 140 IAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNP-QSTLVATGSMD 198
Query: 322 KSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTL 381
+ L+D ++ +E + + S +I +++N S + + D V DA + + + L
Sbjct: 199 TTAKLWDIQNGEEVYTLRGHSAEIISLSFN-TSGDRIITGSFDHTVVVWDADTGRKVNIL 257
Query: 382 NAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
H EIS + ++T S DK K+WD
Sbjct: 258 IGHCAEISSASFNWDC-SLILTGSMDKTCKLWD 289
Score = 63.9 bits (154), Expect = 3e-10
Identities = 55/221 (24%), Positives = 98/221 (44%), Gaps = 30/221 (13%)
Query: 194 LNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAE 253
L+F+P +A G+M ++WD + + E V+TL
Sbjct: 183 LSFNPQ-----STLVATGSMDTTAKLWD---IQNGEEVYTL------------------R 216
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH+ ++ LS+N ++ + S D+TV++WD G+ L H ++ + F+ ++
Sbjct: 217 GHSAEIISLSFNTSGDRII-TGSFDHTVVVWDADTGRKVNILIGHCAEISSASFN-WDCS 274
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
+++GS DK+ L+D + + +I +++ AS D G A
Sbjct: 275 LILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASAD-GTARIFSAA 333
Query: 374 SDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
+ K I L H EIS + + Q L+T S+DK +IWD
Sbjct: 334 TRKCIAKLEGHEGEISKISFNPQ-GNHLLTGSSDKTARIWD 373
Score = 54.3 bits (129), Expect = 3e-07
Identities = 49/213 (23%), Positives = 89/213 (41%), Gaps = 27/213 (12%)
Query: 202 DSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLD 261
+++G+ I G+ + VWD D G+K + GH +
Sbjct: 228 NTSGDRIITGSFDHTVVVWDADT---------------------GRKVNILIGHCAEISS 266
Query: 262 LSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYD 321
S+N +L + S D T LWD + GK A+L H D++ F + + + + S D
Sbjct: 267 ASFNWDCSLIL-TGSMDKTCKLWDATNGKCVATLTGHDDEILDSCF-DYTGKLIATASAD 324
Query: 322 KSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTL 381
+ ++ + ++ G+I ++++N H L + D DA++ + + L
Sbjct: 325 GTARIFSAATRKCIAKLEGHEGEISKISFNP-QGNHLLTGSSDKTARIWDAQTGQCLQVL 383
Query: 382 NAHNDEISGLDLSSQIKG-CLVTASADKYVKIW 413
H DEI + KG ++T S D +IW
Sbjct: 384 EGHTDEI--FSCAFNYKGNIVITGSKDNTCRIW 414
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 66.2 bits (160), Expect = 6e-11
Identities = 57/219 (26%), Positives = 85/219 (38%), Gaps = 40/219 (18%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH LSWN + L SAS D+TV LWD++ G + +A+
Sbjct: 174 GHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIV--------------DAK 219
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
+ +G S +E V W+ F + DD + D R
Sbjct: 220 AIFTGH----------------------SAVVEDVAWHLLHESLFGSVADDQKLMIWDTR 257
Query: 374 SD---KPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKM 430
S+ KP ++AH E++ L + + L T SADK V +WD+ + L H+ +
Sbjct: 258 SNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKL-HTFESHK 316
Query: 431 GVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEA 469
+F P I A G L VWD+S + A
Sbjct: 317 DEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSA 355
Score = 43.1 bits (100), Expect = 6e-04
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query: 247 KKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDM-SLGKPAASLAVHTDKVQTL 305
K S + HT V LS+N +LA+ SAD TV LWD+ +L + H D++ +
Sbjct: 263 KPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQV 322
Query: 306 QFHPFEAQTLISGSYDKSVALYD 328
+ P L S D+ + ++D
Sbjct: 323 HWSPHNETILASSGTDRRLNVWD 345
Score = 37.7 bits (86), Expect = 0.025
Identities = 34/159 (21%), Positives = 63/159 (39%), Gaps = 38/159 (23%)
Query: 183 LLSAYPLSVEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKK 242
L+ A+ V L+F+P + +A G+ + +WDL
Sbjct: 267 LVDAHTAEVNCLSFNPYSEF----ILATGSADKTVALWDL-------------------- 302
Query: 243 KKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMS-LGK----------P 291
+ K + E H D + + W+ +LAS+ D + +WD+S +G+ P
Sbjct: 303 RNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGP 362
Query: 292 AASLAV---HTDKVQTLQFHPFEAQTLISGSYDKSVALY 327
L + HT K+ ++P E + S S D + ++
Sbjct: 363 PELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIW 401
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit
[Homo sapiens]
Length = 340
Score = 65.1 bits (157), Expect = 1e-10
Identities = 68/284 (23%), Positives = 120/284 (42%), Gaps = 41/284 (14%)
Query: 184 LSAYPLSVEWLN---FDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSK 240
+ A PL W+ + PS GNY+A G + + +++L K
Sbjct: 90 MHAIPLRSSWVMTCAYAPS-----GNYVACGGLDNICSIYNL-----------------K 127
Query: 241 KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTD 300
++ + S GHT + + L + + ++S D T LWD+ + + H+
Sbjct: 128 TREGNVRVSRELPGHTGYLSCCRF--LDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSG 185
Query: 301 KVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSP--CHF 358
V +L P + +T +SG+ D S L+D R + F+G + + F P F
Sbjct: 186 DVMSLSLSP-DMRTFVSGACDASSKLWDIR---DGMCRQSFTGHVSDINAVSFFPNGYAF 241
Query: 359 LASTDDGFVYNLDARSDKPIFTLNAHNDEISGL-DLSSQIKGCLVTASADKY-VKIWDIL 416
+DD D R+D+ + L +H++ I G+ ++ G L+ A D + +WD L
Sbjct: 242 ATGSDDATCRLFDLRADQELL-LYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTL 300
Query: 417 -GDRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWD 459
GDR ++ D ++ L + D A G LR+W+
Sbjct: 301 KGDRAGVLAGHDNRVSCLGVT----DDGMAVATGSWDSFLRIWN 340
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 13/168 (7%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH + + W R +L SAS D +I+WD ++ + + V T + P
Sbjct: 53 GHLAKIYAMHWGYDSR-LLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAP-SGN 110
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFL------ASTDDGFV 367
+ G D ++Y+ ++ + + R+ S ++ T + S C FL S+ D
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRV---SRELPGHT-GYLSCCRFLDDSQIVTSSGDTTC 166
Query: 368 YNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
D + + T H+ ++ L LS ++ V+ + D K+WDI
Sbjct: 167 ALWDIETAQQTTTFTGHSGDVMSLSLSPDMR-TFVSGACDASSKLWDI 213
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 65.1 bits (157), Expect = 1e-10
Identities = 70/282 (24%), Positives = 117/282 (41%), Gaps = 41/282 (14%)
Query: 186 AYPLSVEWLN---FDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKK 242
A PL W+ + PS GNY+A G + + +++L K +
Sbjct: 92 AIPLRSSWVMTCAYAPS-----GNYVACGGLDNICSIYNL-----------------KTR 129
Query: 243 KKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKV 302
+ + S GHT + + L N + ++S D T LWD+ G+ + HT V
Sbjct: 130 EGNVRVSRELAGHTGYLSCCRF--LDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDV 187
Query: 303 QTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSP--CHFLA 360
+L P + + +SG+ D S L+D R E F+G + F P F
Sbjct: 188 MSLSLAP-DTRLFVSGACDASAKLWDVR---EGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 361 STDDGFVYNLDARSDKPIFTLNAHNDEISGL-DLSSQIKGCLVTASADKY-VKIWDIL-G 417
+DD D R+D+ + T +H++ I G+ +S G L+ A D + +WD L
Sbjct: 244 GSDDATCRLFDLRADQELMTY-SHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA 302
Query: 418 DRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWD 459
DR ++ D ++ L + D A G L++W+
Sbjct: 303 DRAGVLAGHDNRVSCLGVT----DDGMAVATGSWDSFLKIWN 340
Score = 43.5 bits (101), Expect = 4e-04
Identities = 37/169 (21%), Positives = 69/169 (40%), Gaps = 15/169 (8%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH + + W R +L SAS D +I+WD ++ + + V T + P
Sbjct: 53 GHLAKIYAMHWGTDSR-LLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP-SGN 110
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWR-FSGQIERVTWNHFSPCHFL------ASTDDGF 366
+ G D ++Y+ ++ + + R+ R +G + S C FL S+ D
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHT-----GYLSCCRFLDDNQIVTSSGDTT 165
Query: 367 VYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
D + + T H ++ L L+ + V+ + D K+WD+
Sbjct: 166 CALWDIETGQQTTTFTGHTGDVMSLSLAPDTR-LFVSGACDASAKLWDV 213
>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
[Homo sapiens]
Length = 340
Score = 65.1 bits (157), Expect = 1e-10
Identities = 69/282 (24%), Positives = 119/282 (42%), Gaps = 41/282 (14%)
Query: 186 AYPLSVEWLN---FDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKK 242
A PL W+ + PS GN++A G + + ++ L K +
Sbjct: 92 AIPLRSSWVMTCAYAPS-----GNFVACGGLDNICSIYSL-----------------KTR 129
Query: 243 KKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKV 302
+ + S GHT + + L N + ++S D T LWD+ G+ A H+ V
Sbjct: 130 EGNVRVSRELPGHTGYLSCCRF--LDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDV 187
Query: 303 QTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSP--CHFLA 360
+L P + +T +SG+ D S+ L+D R +S F G + F P F
Sbjct: 188 MSLSLAP-DGRTFVSGACDASIKLWDVR---DSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 361 STDDGFVYNLDARSDKPIFTLNAHNDEISGL-DLSSQIKGCLVTASADKY-VKIWDIL-G 417
+DD D R+D+ + + +H++ I G+ ++ G L+ A D + IWD + G
Sbjct: 244 GSDDATCRLFDLRADQELL-MYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKG 302
Query: 418 DRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWD 459
DR ++ D ++ L + D A G L++W+
Sbjct: 303 DRAGVLAGHDNRVSCLGVT----DDGMAVATGSWDSFLKIWN 340
Score = 40.0 bits (92), Expect = 0.005
Identities = 36/168 (21%), Positives = 70/168 (41%), Gaps = 13/168 (7%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH + + W R +L SAS D +I+WD ++ + + V T + P
Sbjct: 53 GHLAKIYAMHWGTDSR-LLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAP-SGN 110
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFL------ASTDDGFV 367
+ G D ++Y ++ + + R+ S ++ T + S C FL S+ D
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRV---SRELPGHT-GYLSCCRFLDDNQIITSSGDTTC 166
Query: 368 YNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
D + + H+ ++ L L+ + V+ + D +K+WD+
Sbjct: 167 ALWDIETGQQTVGFAGHSGDVMSLSLAPDGR-TFVSGACDASIKLWDV 213
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 62.8 bits (151), Expect = 7e-10
Identities = 52/208 (25%), Positives = 83/208 (39%), Gaps = 48/208 (23%)
Query: 246 GKKSSSAEGHTDAVLDLSWNKLIR-NVLASASADNTVILWDMSLGKPAASLAVHTDKVQT 304
GK + GHT V W+ +R N++ S S D T+ +W+ G+ +L HT V+
Sbjct: 293 GKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRC 348
Query: 305 LQFH-------------------------------------PFEAQTLISGSYDKSVALY 327
+ H ++ + ++SG+YD V ++
Sbjct: 349 MHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVW 408
Query: 328 DCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDE 387
D P+ + G RV F H ++ + D + D + I TL H
Sbjct: 409 D---PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 465
Query: 388 ISGLDLSSQIKGCLVTASADKYVKIWDI 415
SG++L I LV+ +AD VKIWDI
Sbjct: 466 TSGMELKDNI---LVSGNADSTVKIWDI 490
Score = 50.1 bits (118), Expect = 5e-06
Identities = 51/237 (21%), Positives = 88/237 (37%), Gaps = 49/237 (20%)
Query: 219 VWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASAD 278
VW + D++ + L + G+ + GHT V + L + S S D
Sbjct: 306 VWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMH---LHEKRVVSGSRD 362
Query: 279 NTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRM 338
T+ +WD+ G+ L H V+ +Q+ + + ++SG+YD V ++D P+ +
Sbjct: 363 ATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWD---PETETCL 416
Query: 339 WRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQI- 397
G RV F H ++ + D + D + I TL H SG++L I
Sbjct: 417 HTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNIL 476
Query: 398 ---------------------------------------KGCLVTASADKYVKIWDI 415
K ++T+S D VK+WD+
Sbjct: 477 VSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDL 533
Score = 46.6 bits (109), Expect = 5e-05
Identities = 49/230 (21%), Positives = 96/230 (41%), Gaps = 22/230 (9%)
Query: 247 KKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQ 306
K +GH D V+ + N + S S DNT+ +W GK +L HT V + Q
Sbjct: 253 KSPKVLKGHDDHVITCL--QFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ 310
Query: 307 FHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGF 366
+ISGS D+++ +++ + + H ++ G V H ++ + D
Sbjct: 311 MRD---NIIISGSTDRTLKVWNAETGECIHTLY---GHTSTVRCMHLHEKRVVSGSRDAT 364
Query: 367 VYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSR 426
+ D + + + L H + + + +V+ + D VK+WD + + +H+
Sbjct: 365 LRVWDIETGQCLHVLMGHVAAVRCVQYDGR---RVVSGAYDFMVKVWD--PETETCLHTL 419
Query: 427 DMKMGVLFCSSCCPDLPF--IYAFGGQKE-GLRVWDISTVSSVNEAFGRR 473
++ L F I+ G + +RVWD+ T + ++ G +
Sbjct: 420 QGHTNRVY------SLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQ 463
Score = 36.6 bits (83), Expect = 0.055
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 30/130 (23%)
Query: 205 GNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSW 264
G ++ G++ I VWD++ G + GH S
Sbjct: 433 GIHVVSGSLDTSIRVWDVET---------------------GNCIHTLTGHQSLT---SG 468
Query: 265 NKLIRNVLASASADNTVILWDMSLGKPAASLA---VHTDKVQTLQFHPFEAQTLISGSYD 321
+L N+L S +AD+TV +WD+ G+ +L H V LQF+ +I+ S D
Sbjct: 469 MELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN---KNFVITSSDD 525
Query: 322 KSVALYDCRS 331
+V L+D ++
Sbjct: 526 GTVKLWDLKT 535
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/85 (24%), Positives = 34/85 (40%), Gaps = 21/85 (24%)
Query: 206 NYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWN 265
N + GN +++WD+ L+ + H AV L +N
Sbjct: 474 NILVSGNADSTVKIWDIKTGQCLQTL------------------QGPNKHQSAVTCLQFN 515
Query: 266 KLIRNVLASASADNTVILWDMSLGK 290
K N + ++S D TV LWD+ G+
Sbjct: 516 K---NFVITSSDDGTVKLWDLKTGE 537
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 62.8 bits (151), Expect = 7e-10
Identities = 52/208 (25%), Positives = 83/208 (39%), Gaps = 48/208 (23%)
Query: 246 GKKSSSAEGHTDAVLDLSWNKLIR-NVLASASADNTVILWDMSLGKPAASLAVHTDKVQT 304
GK + GHT V W+ +R N++ S S D T+ +W+ G+ +L HT V+
Sbjct: 411 GKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRC 466
Query: 305 LQFH-------------------------------------PFEAQTLISGSYDKSVALY 327
+ H ++ + ++SG+YD V ++
Sbjct: 467 MHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVW 526
Query: 328 DCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDE 387
D P+ + G RV F H ++ + D + D + I TL H
Sbjct: 527 D---PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 583
Query: 388 ISGLDLSSQIKGCLVTASADKYVKIWDI 415
SG++L I LV+ +AD VKIWDI
Sbjct: 584 TSGMELKDNI---LVSGNADSTVKIWDI 608
Score = 50.1 bits (118), Expect = 5e-06
Identities = 51/237 (21%), Positives = 88/237 (37%), Gaps = 49/237 (20%)
Query: 219 VWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASAD 278
VW + D++ + L + G+ + GHT V + L + S S D
Sbjct: 424 VWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMH---LHEKRVVSGSRD 480
Query: 279 NTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRM 338
T+ +WD+ G+ L H V+ +Q+ + + ++SG+YD V ++D P+ +
Sbjct: 481 ATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWD---PETETCL 534
Query: 339 WRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQI- 397
G RV F H ++ + D + D + I TL H SG++L I
Sbjct: 535 HTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNIL 594
Query: 398 ---------------------------------------KGCLVTASADKYVKIWDI 415
K ++T+S D VK+WD+
Sbjct: 595 VSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDL 651
Score = 46.6 bits (109), Expect = 5e-05
Identities = 49/230 (21%), Positives = 96/230 (41%), Gaps = 22/230 (9%)
Query: 247 KKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQ 306
K +GH D V+ + N + S S DNT+ +W GK +L HT V + Q
Sbjct: 371 KSPKVLKGHDDHVITCL--QFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ 428
Query: 307 FHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGF 366
+ISGS D+++ +++ + + H ++ G V H ++ + D
Sbjct: 429 MRD---NIIISGSTDRTLKVWNAETGECIHTLY---GHTSTVRCMHLHEKRVVSGSRDAT 482
Query: 367 VYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSR 426
+ D + + + L H + + + +V+ + D VK+WD + + +H+
Sbjct: 483 LRVWDIETGQCLHVLMGHVAAVRCVQYDGR---RVVSGAYDFMVKVWD--PETETCLHTL 537
Query: 427 DMKMGVLFCSSCCPDLPF--IYAFGGQKE-GLRVWDISTVSSVNEAFGRR 473
++ L F I+ G + +RVWD+ T + ++ G +
Sbjct: 538 QGHTNRVY------SLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQ 581
Score = 36.6 bits (83), Expect = 0.055
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 30/130 (23%)
Query: 205 GNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSW 264
G ++ G++ I VWD++ G + GH S
Sbjct: 551 GIHVVSGSLDTSIRVWDVET---------------------GNCIHTLTGHQSLT---SG 586
Query: 265 NKLIRNVLASASADNTVILWDMSLGKPAASLA---VHTDKVQTLQFHPFEAQTLISGSYD 321
+L N+L S +AD+TV +WD+ G+ +L H V LQF+ +I+ S D
Sbjct: 587 MELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN---KNFVITSSDD 643
Query: 322 KSVALYDCRS 331
+V L+D ++
Sbjct: 644 GTVKLWDLKT 653
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/85 (24%), Positives = 34/85 (40%), Gaps = 21/85 (24%)
Query: 206 NYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWN 265
N + GN +++WD+ L+ + H AV L +N
Sbjct: 592 NILVSGNADSTVKIWDIKTGQCLQTL------------------QGPNKHQSAVTCLQFN 633
Query: 266 KLIRNVLASASADNTVILWDMSLGK 290
K N + ++S D TV LWD+ G+
Sbjct: 634 K---NFVITSSDDGTVKLWDLKTGE 655
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 62.8 bits (151), Expect = 7e-10
Identities = 52/208 (25%), Positives = 83/208 (39%), Gaps = 48/208 (23%)
Query: 246 GKKSSSAEGHTDAVLDLSWNKLIR-NVLASASADNTVILWDMSLGKPAASLAVHTDKVQT 304
GK + GHT V W+ +R N++ S S D T+ +W+ G+ +L HT V+
Sbjct: 331 GKCLRTLVGHTGGV----WSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRC 386
Query: 305 LQFH-------------------------------------PFEAQTLISGSYDKSVALY 327
+ H ++ + ++SG+YD V ++
Sbjct: 387 MHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVW 446
Query: 328 DCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDE 387
D P+ + G RV F H ++ + D + D + I TL H
Sbjct: 447 D---PETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSL 503
Query: 388 ISGLDLSSQIKGCLVTASADKYVKIWDI 415
SG++L I LV+ +AD VKIWDI
Sbjct: 504 TSGMELKDNI---LVSGNADSTVKIWDI 528
Score = 50.1 bits (118), Expect = 5e-06
Identities = 51/237 (21%), Positives = 88/237 (37%), Gaps = 49/237 (20%)
Query: 219 VWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASAD 278
VW + D++ + L + G+ + GHT V + L + S S D
Sbjct: 344 VWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMH---LHEKRVVSGSRD 400
Query: 279 NTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRM 338
T+ +WD+ G+ L H V+ +Q+ + + ++SG+YD V ++D P+ +
Sbjct: 401 ATLRVWDIETGQCLHVLMGHVAAVRCVQY---DGRRVVSGAYDFMVKVWD---PETETCL 454
Query: 339 WRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQI- 397
G RV F H ++ + D + D + I TL H SG++L I
Sbjct: 455 HTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNIL 514
Query: 398 ---------------------------------------KGCLVTASADKYVKIWDI 415
K ++T+S D VK+WD+
Sbjct: 515 VSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDL 571
Score = 46.6 bits (109), Expect = 5e-05
Identities = 49/230 (21%), Positives = 96/230 (41%), Gaps = 22/230 (9%)
Query: 247 KKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQ 306
K +GH D V+ + N + S S DNT+ +W GK +L HT V + Q
Sbjct: 291 KSPKVLKGHDDHVITCL--QFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQ 348
Query: 307 FHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGF 366
+ISGS D+++ +++ + + H ++ G V H ++ + D
Sbjct: 349 MRD---NIIISGSTDRTLKVWNAETGECIHTLY---GHTSTVRCMHLHEKRVVSGSRDAT 402
Query: 367 VYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSR 426
+ D + + + L H + + + +V+ + D VK+WD + + +H+
Sbjct: 403 LRVWDIETGQCLHVLMGHVAAVRCVQYDGR---RVVSGAYDFMVKVWD--PETETCLHTL 457
Query: 427 DMKMGVLFCSSCCPDLPF--IYAFGGQKE-GLRVWDISTVSSVNEAFGRR 473
++ L F I+ G + +RVWD+ T + ++ G +
Sbjct: 458 QGHTNRVY------SLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQ 501
Score = 36.6 bits (83), Expect = 0.055
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 30/130 (23%)
Query: 205 GNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSW 264
G ++ G++ I VWD++ G + GH S
Sbjct: 471 GIHVVSGSLDTSIRVWDVET---------------------GNCIHTLTGHQSLT---SG 506
Query: 265 NKLIRNVLASASADNTVILWDMSLGKPAASLA---VHTDKVQTLQFHPFEAQTLISGSYD 321
+L N+L S +AD+TV +WD+ G+ +L H V LQF+ +I+ S D
Sbjct: 507 MELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFN---KNFVITSSDD 563
Query: 322 KSVALYDCRS 331
+V L+D ++
Sbjct: 564 GTVKLWDLKT 573
Score = 32.0 bits (71), Expect = 1.3
Identities = 21/85 (24%), Positives = 34/85 (40%), Gaps = 21/85 (24%)
Query: 206 NYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWN 265
N + GN +++WD+ L+ + H AV L +N
Sbjct: 512 NILVSGNADSTVKIWDIKTGQCLQTL------------------QGPNKHQSAVTCLQFN 553
Query: 266 KLIRNVLASASADNTVILWDMSLGK 290
K N + ++S D TV LWD+ G+
Sbjct: 554 K---NFVITSSDDGTVKLWDLKTGE 575
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 62.8 bits (151), Expect = 7e-10
Identities = 56/226 (24%), Positives = 101/226 (44%), Gaps = 7/226 (3%)
Query: 251 SAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPF 310
S EGH V+ + + + + AS+S D + LWD+ GK S+ TL F P
Sbjct: 59 SLEGHQLGVVSVDISHTLP-IAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSP- 116
Query: 311 EAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNL 370
++Q L +G++ V ++ S + + + I + ++ + + DG +
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGK-YLASGAIDGIINIF 175
Query: 371 DARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKM 430
D + K + TL H I L S + LVTAS D Y+KI+D+ +L +
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQ-LLVTASDDGYIKIYDV--QHANLAGTLSGHA 232
Query: 431 GVLFCSSCCPDLPFIYAFGGQKEGLRVWDISTVSSVNEAFGRRERL 476
+ + CPD + K ++VWD+ T + V+ F ++++
Sbjct: 233 SWVLNVAFCPDDTHFVSSSSDK-SVKVWDVGTRTCVHTFFDHQDQV 277
Score = 49.7 bits (117), Expect = 6e-06
Identities = 42/173 (24%), Positives = 83/173 (47%), Gaps = 8/173 (4%)
Query: 244 KKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQ 303
+ GKK S + +L ++++ LAS + D + ++D++ GK +L H ++
Sbjct: 136 ESGKKEYSLDTRGKFILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIR 194
Query: 304 TLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSP--CHFLAS 361
+L F P ++Q L++ S D + +YD + + + + SG V F P HF++S
Sbjct: 195 SLTFSP-DSQLLVTASDDGYIKIYDVQHANLAGTL---SGHASWVLNVAFCPDDTHFVSS 250
Query: 362 TDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
+ D V D + + T H D++ G+ + +V+ D+ + I+D
Sbjct: 251 SSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGN-GSKIVSVGDDQEIHIYD 302
>gi|14150171 THO complex 3 [Homo sapiens]
Length = 351
Score = 62.8 bits (151), Expect = 7e-10
Identities = 44/174 (25%), Positives = 83/174 (47%), Gaps = 5/174 (2%)
Query: 242 KKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDK 301
+K + K ++ GH D+V L W+ ++ +AS D T+ +WD+ K A++ +
Sbjct: 85 EKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGEN 144
Query: 302 VQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLAS 361
+ + + P + QT+ G+ D V D ++ S +F ++ ++WN+ + FL +
Sbjct: 145 I-NICWSP-DGQTIAVGNKDDVVTFIDAKT-HRSKAEEQFKFEVNEISWNNDNNMFFL-T 200
Query: 362 TDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
+G + L KP+ ++NAH + K T SAD V +WD+
Sbjct: 201 NGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGK-YFATGSADALVSLWDV 253
>gi|217330644 WD repeat domain 12 protein [Homo sapiens]
Length = 423
Score = 62.0 bits (149), Expect = 1e-09
Identities = 54/216 (25%), Positives = 101/216 (46%), Gaps = 17/216 (7%)
Query: 202 DSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSS-----SAEGHT 256
D +G G+ ++++W D + + ++ KK+K + + + GH
Sbjct: 198 DGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHM 257
Query: 257 DAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKV-QTLQFHPFEAQTL 315
+AV + W+ + SAS D+T+ +WD+ G ++L +KV + + P + L
Sbjct: 258 EAVSSVLWSDA--EEICSASWDHTIRVWDVESGSLKSTLT--GNKVFNCISYSPL-CKRL 312
Query: 316 ISGSYDKSVALYDCRSPD---ESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDA 372
SGS D+ + L+D R+ D S + +G + V W+ ++ + D V D
Sbjct: 313 ASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDT 372
Query: 373 RSDK-PIFTLNAHNDEISGLDLSSQIKGCLVTASAD 407
RS K P++ L AH D++ +D + G L++ AD
Sbjct: 373 RSCKAPLYDLAAHEDKVLSVDWTD--TGLLLSGGAD 406
Score = 51.6 bits (122), Expect = 2e-06
Identities = 55/232 (23%), Positives = 92/232 (39%), Gaps = 30/232 (12%)
Query: 237 KLSKKKKKKGKKSSSAEGHTDAVLDLSWNK--LIRNVLASASADNTVILWDMSLG----K 290
K S+ +GK + GHTD V D++W K + +L SAS D T++LW+ ++ K
Sbjct: 121 KTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVK 180
Query: 291 PAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTW 350
H V ++ SGS+DK + ++ DE M + +
Sbjct: 181 ALHCCRGHAGSVDSIAVDG-SGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNR------ 233
Query: 351 NHFSPCHFLASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYV 410
P + G + PI TL+ H + +S + S + C +AS D +
Sbjct: 234 ----PRKKQKTEQLGL-------TRTPIVTLSGHMEAVSSVLWSDAEEIC--SASWDHTI 280
Query: 411 KIWDILGDRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDIST 462
++WD+ + + + S C L A G +R+WD T
Sbjct: 281 RVWDVESGSLKSTLTGNKVFNCISYSPLCKRL----ASGSTDRHIRLWDPRT 328
Score = 43.5 bits (101), Expect = 4e-04
Identities = 34/90 (37%), Positives = 41/90 (45%), Gaps = 6/90 (6%)
Query: 249 SSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWD-MSLGKPAASLAVHTDKVQTLQF 307
S S HT V + W+ L S S DN V LWD S P LA H DKV ++ +
Sbjct: 335 SLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDW 394
Query: 308 HPFEAQTLISGSYDKSVALYDCR-SPDESH 336
+ L+SG D LY R SP SH
Sbjct: 395 --TDTGLLLSGGADNK--LYSYRYSPTTSH 420
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 61.6 bits (148), Expect = 2e-09
Identities = 56/207 (27%), Positives = 99/207 (47%), Gaps = 37/207 (17%)
Query: 181 DILLSAYPLSVEWLN---FDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSK 237
++LL+ + +WL+ F PS G+ +A + +++WDL
Sbjct: 385 NVLLTGFG-HTDWLSDCCFHPS-----GDKLATSSGDTTVKLWDLC-------------- 424
Query: 238 LSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAV 297
KG + EGH+ AV +W+ N +AS+S D T +WD++ + +L
Sbjct: 425 -------KGDCILTFEGHSRAVWSCTWHSC-GNFVASSSLDKTSKIWDVNSERCRCTLYG 476
Query: 298 HTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSP-C 356
HTD V +++F PF + TL++ S DK+++++D R+ ++ G + + F P
Sbjct: 477 HTDSVNSIEFFPF-SNTLLTSSADKTLSIWDARTGICEQSLY---GHMHSINDAIFDPRG 532
Query: 357 HFLASTDDGFVYNL-DARSDKPIFTLN 382
H +AS D V L D R PI +++
Sbjct: 533 HMIASCDACGVTKLWDFRKLLPIVSID 559
Score = 45.8 bits (107), Expect = 9e-05
Identities = 44/151 (29%), Positives = 69/151 (45%), Gaps = 13/151 (8%)
Query: 269 RNVLASASADNTVILWDMSLGKPAASLAV----HTDKVQTLQFHPFEAQTLISGSYDKSV 324
+++L S D LW + LG P ++ + HTD + FHP L + S D +V
Sbjct: 364 KDILVSCGEDR---LWKV-LGLPKCNVLLTGFGHTDWLSDCCFHP-SGDKLATSSGDTTV 418
Query: 325 ALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTD-DGFVYNLDARSDKPIFTLNA 383
L+D D S + TW+ S +F+AS+ D D S++ TL
Sbjct: 419 KLWDLCKGDCILTFEGHSRAVWSCTWH--SCGNFVASSSLDKTSKIWDVNSERCRCTLYG 476
Query: 384 HNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
H D ++ ++ L+T+SADK + IWD
Sbjct: 477 HTDSVNSIEFFP-FSNTLLTSSADKTLSIWD 506
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/170 (28%), Positives = 87/170 (51%), Gaps = 5/170 (2%)
Query: 246 GKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTL 305
GK + GH + D++W+ + L SAS D T+ LWD+ GK +L H++ V
Sbjct: 73 GKYEKTLYGHNLEISDVAWSS-DSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCC 131
Query: 306 QFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDG 365
F+P + +ISGS+D++V +++ ++ + S + V +N S ++ + DG
Sbjct: 132 NFNP-PSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFN-CSGSLIVSGSYDG 189
Query: 366 FVYNLDARSDKPIFTL-NAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
DA S + + TL + N +S + S K ++TA+ D +K+WD
Sbjct: 190 LCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGK-YILTATLDNTLKLWD 238
Score = 55.8 bits (133), Expect = 9e-08
Identities = 49/201 (24%), Positives = 90/201 (44%), Gaps = 10/201 (4%)
Query: 244 KKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQ 303
+ GK + +GH++ V ++N N++ S S D TV +W++ GK +L+ H+D V
Sbjct: 113 RSGKCLKTLKGHSNYVFCCNFNPP-SNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVS 171
Query: 304 TLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSP--CHFLAS 361
+ F+ ++SGSYD ++D S + V++ FSP + L +
Sbjct: 172 AVHFN-CSGSLIVSGSYDGLCRIWDAASGQCLKTL--VDDDNPPVSFVKFSPNGKYILTA 228
Query: 362 TDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKG--CLVTASADKYVKIWDILGDR 419
T D + D + + T H +E + + + G +V+ S D V IW++
Sbjct: 229 TLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNL--QT 286
Query: 420 PSLVHSRDMKMGVLFCSSCCP 440
+V V+ ++C P
Sbjct: 287 KEIVQKLQGHTDVVISAACHP 307
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/163 (27%), Positives = 81/163 (49%), Gaps = 8/163 (4%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GHT+AV + ++ LAS+SAD +I+W GK +L H ++ + + ++
Sbjct: 39 GHTEAVSSVKFSPN-GEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSS-DSS 96
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCH--FLASTDDGFVYNLD 371
L+S S DK++ L+D RS + G V +F+P ++ + D V +
Sbjct: 97 RLVSASDDKTLKLWDVRS---GKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWE 153
Query: 372 ARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWD 414
++ K + TL+AH+D +S + + +V+ S D +IWD
Sbjct: 154 VKTGKCLKTLSAHSDPVSAVHFNCS-GSLIVSGSYDGLCRIWD 195
Score = 30.8 bits (68), Expect = 3.0
Identities = 31/142 (21%), Positives = 55/142 (38%), Gaps = 33/142 (23%)
Query: 191 VEWLNFDPSPDDSTGNYIAVGNMTPVIEVWDLDIVDSLEPVFTLGSKLSKKKKKKGKKSS 250
V ++ F P+ G YI + +++WD +G+
Sbjct: 213 VSFVKFSPN-----GKYILTATLDNTLKLWDYS---------------------RGRCLK 246
Query: 251 SAEGHTDAVLDLSWNKLIRNV--LASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFH 308
+ GH + + N + + S S DN V +W++ + L HTD V + H
Sbjct: 247 TYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACH 306
Query: 309 PFEAQTLISGS---YDKSVALY 327
P E LI+ + DK++ L+
Sbjct: 307 PTE--NLIASAALENDKTIKLW 326
>gi|4502477 beta-transducin repeat containing protein isoform 2
[Homo sapiens]
Length = 569
Score = 60.8 bits (146), Expect = 3e-09
Identities = 42/162 (25%), Positives = 85/162 (52%), Gaps = 9/162 (5%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GHT +VL L +++ V+ + S+D+TV +WD++ G+ +L H + V L+F+
Sbjct: 305 GHTGSVLCLQYDE---RVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFN---NG 358
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
+++ S D+S+A++D SP + G V F + ++++ D + +
Sbjct: 359 MMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS 418
Query: 374 SDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
+ + + TLN H I+ L ++ +V+ S+D +++WDI
Sbjct: 419 TCEFVRTLNGHKRGIACLQYRDRL---VVSGSSDNTIRLWDI 457
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/207 (21%), Positives = 84/207 (40%), Gaps = 19/207 (9%)
Query: 272 LASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRS 331
+ S DNT+ +WD + + L HT V LQ ++ + +I+GS D +V ++D +
Sbjct: 280 IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ---YDERVIITGSSDSTVRVWDVNT 336
Query: 332 PDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIF---TLNAHNDEI 388
+ + + E V F+ + + D + D S I L H +
Sbjct: 337 GEMLNTLIH---HCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 393
Query: 389 SGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHS-RDMKMGVLFCSSCCPDLPFIYA 447
+ +D + +V+AS D+ +K+W+ V + K G+ +C +
Sbjct: 394 NVVDFDDKY---IVSASGDRTIKVWNT--STCEFVRTLNGHKRGI----ACLQYRDRLVV 444
Query: 448 FGGQKEGLRVWDISTVSSVNEAFGRRE 474
G +R+WDI + + G E
Sbjct: 445 SGSSDNTIRLWDIECGACLRVLEGHEE 471
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH + L + ++ S S+DNT+ LWD+ G L H + V+ ++ F+ +
Sbjct: 428 GHKRGIACLQYRD---RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR---FDNK 481
Query: 314 TLISGSYDKSVALYD 328
++SG+YD + ++D
Sbjct: 482 RIVSGAYDGKIKVWD 496
>gi|16117783 beta-transducin repeat containing protein isoform 1
[Homo sapiens]
Length = 605
Score = 60.8 bits (146), Expect = 3e-09
Identities = 42/162 (25%), Positives = 85/162 (52%), Gaps = 9/162 (5%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GHT +VL L +++ V+ + S+D+TV +WD++ G+ +L H + V L+F+
Sbjct: 341 GHTGSVLCLQYDE---RVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFN---NG 394
Query: 314 TLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDAR 373
+++ S D+S+A++D SP + G V F + ++++ D + +
Sbjct: 395 MMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTS 454
Query: 374 SDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
+ + + TLN H I+ L ++ +V+ S+D +++WDI
Sbjct: 455 TCEFVRTLNGHKRGIACLQYRDRL---VVSGSSDNTIRLWDI 493
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/207 (21%), Positives = 84/207 (40%), Gaps = 19/207 (9%)
Query: 272 LASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRS 331
+ S DNT+ +WD + + L HT V LQ ++ + +I+GS D +V ++D +
Sbjct: 316 IVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQ---YDERVIITGSSDSTVRVWDVNT 372
Query: 332 PDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARSDKPIF---TLNAHNDEI 388
+ + + E V F+ + + D + D S I L H +
Sbjct: 373 GEMLNTLIH---HCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV 429
Query: 389 SGLDLSSQIKGCLVTASADKYVKIWDILGDRPSLVHS-RDMKMGVLFCSSCCPDLPFIYA 447
+ +D + +V+AS D+ +K+W+ V + K G+ +C +
Sbjct: 430 NVVDFDDKY---IVSASGDRTIKVWNT--STCEFVRTLNGHKRGI----ACLQYRDRLVV 480
Query: 448 FGGQKEGLRVWDISTVSSVNEAFGRRE 474
G +R+WDI + + G E
Sbjct: 481 SGSSDNTIRLWDIECGACLRVLEGHEE 507
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/75 (28%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQ 313
GH + L + ++ S S+DNT+ LWD+ G L H + V+ ++ F+ +
Sbjct: 464 GHKRGIACLQYRD---RLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIR---FDNK 517
Query: 314 TLISGSYDKSVALYD 328
++SG+YD + ++D
Sbjct: 518 RIVSGAYDGKIKVWD 532
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/221 (25%), Positives = 90/221 (40%), Gaps = 9/221 (4%)
Query: 241 KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTD 300
K + K S HT+ + S+ +L +AS D T LWD+ G+ S H
Sbjct: 138 KNENMAAKKKSVAMHTNYLSACSFTNSDMQIL-TASGDGTCALWDVESGQLLQSFHGHGA 196
Query: 301 KVQTLQFHPFE-AQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFL 359
V L P E T +SG DK ++D RS I V + + S F
Sbjct: 197 DVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY-YPSGDAFA 255
Query: 360 ASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKY-VKIWDIL-G 417
+ +DD D R+D+ + + + + + G L+ A + Y + +WD+L G
Sbjct: 256 SGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKG 315
Query: 418 DRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVW 458
R S++ + ++ L S PD + G LRVW
Sbjct: 316 SRVSILFGHENRVSTLRVS---PD-GTAFCSGSWDHTLRVW 352
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/203 (23%), Positives = 86/203 (42%), Gaps = 19/203 (9%)
Query: 221 DLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNT 280
D+++ E V LG + K ++ + +GH + VL + W K R ++ S+S D
Sbjct: 35 DVELHQVAERVEALGQFVMKTRR-------TLKGHGNKVLCMDWCKDKRRIV-SSSQDGK 86
Query: 281 VILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWR 340
VI+WD ++ + V + P + G D ++Y + D++ M
Sbjct: 87 VIVWDSFTTNKEHAVTMPCTWVMACAYAP-SGCAIACGGLDNKCSVYPL-TFDKNENMAA 144
Query: 341 FSGQIERVTWNHFSPCHF-------LASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDL 393
+ T N+ S C F L ++ DG D S + + + + H ++ LDL
Sbjct: 145 KKKSVAMHT-NYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDL 203
Query: 394 S-SQIKGCLVTASADKYVKIWDI 415
+ S+ V+ DK +WD+
Sbjct: 204 APSETGNTFVSGGCDKKAMVWDM 226
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/221 (25%), Positives = 90/221 (40%), Gaps = 9/221 (4%)
Query: 241 KKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTD 300
K + K S HT+ + S+ +L +AS D T LWD+ G+ S H
Sbjct: 180 KNENMAAKKKSVAMHTNYLSACSFTNSDMQIL-TASGDGTCALWDVESGQLLQSFHGHGA 238
Query: 301 KVQTLQFHPFE-AQTLISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFL 359
V L P E T +SG DK ++D RS I V + + S F
Sbjct: 239 DVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY-YPSGDAFA 297
Query: 360 ASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTASADKY-VKIWDIL-G 417
+ +DD D R+D+ + + + + + G L+ A + Y + +WD+L G
Sbjct: 298 SGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKG 357
Query: 418 DRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVW 458
R S++ + ++ L S PD + G LRVW
Sbjct: 358 SRVSILFGHENRVSTLRVS---PD-GTAFCSGSWDHTLRVW 394
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/203 (23%), Positives = 86/203 (42%), Gaps = 19/203 (9%)
Query: 221 DLDIVDSLEPVFTLGSKLSKKKKKKGKKSSSAEGHTDAVLDLSWNKLIRNVLASASADNT 280
D+++ E V LG + K ++ + +GH + VL + W K R ++ S+S D
Sbjct: 77 DVELHQVAERVEALGQFVMKTRR-------TLKGHGNKVLCMDWCKDKRRIV-SSSQDGK 128
Query: 281 VILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDESHRMWR 340
VI+WD ++ + V + P + G D ++Y + D++ M
Sbjct: 129 VIVWDSFTTNKEHAVTMPCTWVMACAYAP-SGCAIACGGLDNKCSVYPL-TFDKNENMAA 186
Query: 341 FSGQIERVTWNHFSPCHF-------LASTDDGFVYNLDARSDKPIFTLNAHNDEISGLDL 393
+ T N+ S C F L ++ DG D S + + + + H ++ LDL
Sbjct: 187 KKKSVAMHT-NYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDL 245
Query: 394 S-SQIKGCLVTASADKYVKIWDI 415
+ S+ V+ DK +WD+
Sbjct: 246 APSETGNTFVSGGCDKKAMVWDM 268
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 32/222 (14%)
Query: 202 DSTGNYIAVGNMTPVIEVWDLDIV--DSL-----EPVFTLGSKLSKKKKKKGKKSSSAEG 254
D +Y A+ +T I+V++ D V D++ E T SK+S
Sbjct: 430 DRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISC-------------- 475
Query: 255 HTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQT 314
+SW+ +N+LAS+ + TVILWD G+ + H + ++ F+ + +
Sbjct: 476 -------ISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKL 528
Query: 315 LISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARS 374
L SGS D V L+ + D S + V ++ S H D V+ D R+
Sbjct: 529 LASGSDDAKVKLWS-TNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRN 587
Query: 375 DK-PIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
K PI H +S S + +V+AS D +K+W++
Sbjct: 588 TKQPIMVFKGHRKAVSYAKFVSGEE--IVSASTDSQLKLWNV 627
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 32/222 (14%)
Query: 202 DSTGNYIAVGNMTPVIEVWDLDIV--DSL-----EPVFTLGSKLSKKKKKKGKKSSSAEG 254
D +Y A+ +T I+V++ D V D++ E T SK+S
Sbjct: 406 DRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKISC-------------- 451
Query: 255 HTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQT 314
+SW+ +N+LAS+ + TVILWD G+ + H + ++ F+ + +
Sbjct: 452 -------ISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKL 504
Query: 315 LISGSYDKSVALYDCRSPDESHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARS 374
L SGS D V L+ + D S + V ++ S H D V+ D R+
Sbjct: 505 LASGSDDAKVKLWS-TNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCADHCVHYYDLRN 563
Query: 375 DK-PIFTLNAHNDEISGLDLSSQIKGCLVTASADKYVKIWDI 415
K PI H +S S + +V+AS D +K+W++
Sbjct: 564 TKQPIMVFKGHRKAVSYAKFVSGEE--IVSASTDSQLKLWNV 603
>gi|65787364 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 59.7 bits (143), Expect = 6e-09
Identities = 53/221 (23%), Positives = 92/221 (41%), Gaps = 15/221 (6%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDM-------SLGKPAASLAVHTDKVQTLQ 306
GHT VLD+ W V+AS S D TV++W + L +P L HT +V +
Sbjct: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
Query: 307 FHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQ-IERVTWNHFSPCHFLASTDDG 365
+HP L+S D V +++ + +E +R+ I V+WNH + F ++ D
Sbjct: 140 WHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNH-NGSLFCSACKDK 198
Query: 366 FVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTAS----ADKYVKIWDILG-DRP 420
V +D R + ++ + G + T +++ + +WD + P
Sbjct: 199 SVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEP 258
Query: 421 SLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDIS 461
+ D G L PD +Y G +R ++I+
Sbjct: 259 MALQELDSSNGALL-PFYDPDTSVVYVCGKGDSSIRYFEIT 298
Score = 46.2 bits (108), Expect = 7e-05
Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 253 EGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASL-AVHTDKVQTLQFHPFE 311
EGHT V ++W+ RNVL SA DN V++W++ + L ++H D + + ++
Sbjct: 129 EGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWN-HN 187
Query: 312 AQTLISGSYDKSVALYDCR 330
S DKSV + D R
Sbjct: 188 GSLFCSACKDKSVRIIDPR 206
>gi|14149734 coronin, actin binding protein, 1B [Homo sapiens]
Length = 489
Score = 59.7 bits (143), Expect = 6e-09
Identities = 53/221 (23%), Positives = 92/221 (41%), Gaps = 15/221 (6%)
Query: 254 GHTDAVLDLSWNKLIRNVLASASADNTVILWDM-------SLGKPAASLAVHTDKVQTLQ 306
GHT VLD+ W V+AS S D TV++W + L +P L HT +V +
Sbjct: 80 GHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIA 139
Query: 307 FHPFEAQTLISGSYDKSVALYDCRSPDESHRMWRFSGQ-IERVTWNHFSPCHFLASTDDG 365
+HP L+S D V +++ + +E +R+ I V+WNH + F ++ D
Sbjct: 140 WHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNH-NGSLFCSACKDK 198
Query: 366 FVYNLDARSDKPIFTLNAHNDEISGLDLSSQIKGCLVTAS----ADKYVKIWDILG-DRP 420
V +D R + ++ + G + T +++ + +WD + P
Sbjct: 199 SVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEP 258
Query: 421 SLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKEGLRVWDIS 461
+ D G L PD +Y G +R ++I+
Sbjct: 259 MALQELDSSNGALL-PFYDPDTSVVYVCGKGDSSIRYFEIT 298
Score = 46.2 bits (108), Expect = 7e-05
Identities = 26/79 (32%), Positives = 41/79 (51%), Gaps = 2/79 (2%)
Query: 253 EGHTDAVLDLSWNKLIRNVLASASADNTVILWDMSLGKPAASL-AVHTDKVQTLQFHPFE 311
EGHT V ++W+ RNVL SA DN V++W++ + L ++H D + + ++
Sbjct: 129 EGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWN-HN 187
Query: 312 AQTLISGSYDKSVALYDCR 330
S DKSV + D R
Sbjct: 188 GSLFCSACKDKSVRIIDPR 206
>gi|229892270 WD repeats and SOF1 domain containing [Homo sapiens]
Length = 597
Score = 59.3 bits (142), Expect = 8e-09
Identities = 46/185 (24%), Positives = 81/185 (43%), Gaps = 5/185 (2%)
Query: 275 ASADNTVILWDMSLGKPAASLAVHTDKVQTLQFHPFEAQTLISGSYDKSVALYDCRSPDE 334
A+ V +WD P S+ D + +++F+P E L S + D+++ LYD R
Sbjct: 324 ATCGQQVDIWDEQRTNPICSMTWGFDSISSVKFNPIETFLLGSCASDRNIVLYDMRQATP 383
Query: 335 SHRMWRFSGQIERVTWNHFSPCHFLASTDDGFVYNLDARS-DKPIFTLNAHNDEISGLDL 393
++ + + WN F A+ +D +Y D R+ D P+ H + +D
Sbjct: 384 LKKV-ILDMRTNTICWNPMEAFIFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDY 442
Query: 394 SSQIKGCLVTASADKYVKIWDILGDRPSLVHSRDMKMGVLFCSSCCPDLPFIYAFGGQKE 453
S K V+AS DK ++I+ + R V+ +M + C D +I G +
Sbjct: 443 SPTGKE-FVSASFDKSIRIFPVDKSRSREVY-HTKRMQHVICVKWTSDSKYIMC-GSDEM 499
Query: 454 GLRVW 458
+R+W
Sbjct: 500 NIRLW 504
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,215,509
Number of Sequences: 37866
Number of extensions: 963435
Number of successful extensions: 6357
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 184
Number of HSP's successfully gapped in prelim test: 280
Number of HSP's that attempted gapping in prelim test: 4446
Number of HSP's gapped (non-prelim): 1457
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.