Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 5901922
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5901922 cell division cycle 37 protein [Homo sapiens]
(378 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5901922 cell division cycle 37 protein [Homo sapiens] 770 0.0
gi|66773038 cell division cycle 37 homolog (S. cerevisiae)-like ... 223 3e-58
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 7e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 4e-06
gi|148746195 trichohyalin [Homo sapiens] 50 4e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 6e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 48 1e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 48 2e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 48 2e-05
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 48 2e-05
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 48 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 2e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 47 2e-05
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 47 3e-05
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 47 4e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 46 6e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 46 6e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 46 6e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 46 6e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 46 6e-05
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 45 1e-04
gi|31982906 cingulin-like 1 [Homo sapiens] 45 1e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 45 1e-04
gi|16905073 SoxLZ/Sox6 leucine zipper binding protein [Homo sapi... 44 2e-04
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 44 2e-04
gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s... 44 2e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 44 3e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 44 3e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 44 3e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 44 3e-04
>gi|5901922 cell division cycle 37 protein [Homo sapiens]
Length = 378
Score = 770 bits (1988), Expect = 0.0
Identities = 378/378 (100%), Positives = 378/378 (100%)
Query: 1 MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRK 60
MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRK
Sbjct: 1 MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRK 60
Query: 61 VAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLS 120
VAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLS
Sbjct: 61 VAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLS 120
Query: 121 KDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVH 180
KDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVH
Sbjct: 121 KDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVH 180
Query: 181 LVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTK 240
LVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTK
Sbjct: 181 LVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTK 240
Query: 241 IKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYES 300
IKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYES
Sbjct: 241 IKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYES 300
Query: 301 LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKEGEEAGPG 360
LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKEGEEAGPG
Sbjct: 301 LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKEGEEAGPG 360
Query: 361 DPLLEAVPKTGDEKDVSV 378
DPLLEAVPKTGDEKDVSV
Sbjct: 361 DPLLEAVPKTGDEKDVSV 378
>gi|66773038 cell division cycle 37 homolog (S. cerevisiae)-like 1
[Homo sapiens]
Length = 337
Score = 223 bits (567), Expect = 3e-58
Identities = 115/262 (43%), Positives = 164/262 (62%), Gaps = 14/262 (5%)
Query: 44 QKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEA--QQLRKEERSWEQK 101
QK+KE + + CK +AE Q+KL L + + E +A+ +LR+ E W QK
Sbjct: 55 QKQKEFV-KSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREEEWRQK 113
Query: 102 LEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKH 161
E + ++EK W+ D +SKD F+KS +N K ED E K ++F++KYE++I+H
Sbjct: 114 EEALVQREKMCLWSTDAISKDVFNKSFINQDKRKDTED-----EDKSESFMQKYEQKIRH 168
Query: 162 FGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILE 221
FGML RWDDSQ++LSD+ +LVCEETA YL++WC LE E+K ALMEQ+AHQ +VMQFI+E
Sbjct: 169 FGMLSRWDDSQRFLSDHPYLVCEETAKYLILWCFHLEAEKKGALMEQIAHQAVVMQFIME 228
Query: 222 LAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEE 281
+AK+ VDPR CFR FF K K + Y E F +ELEAFK RV R+ + ++
Sbjct: 229 MAKNCNVDPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRV------RLYSQSQSFQPM 282
Query: 282 ERKKRLGPGGLDPVEVYESLPE 303
+ + G+ + + ESLP+
Sbjct: 283 TVQNHVPHSGVGSIGLLESLPQ 304
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 52.4 bits (124), Expect = 7e-07
Identities = 32/113 (28%), Positives = 63/113 (55%), Gaps = 5/113 (4%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQL-RKEER 96
ERM + +K+ E + RE + K+ E + K++E E E + E++Q + +++ +EE+
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQE--EKMWEQEEKMQEQEEKMWEQEEK 617
Query: 97 SWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHK 149
WEQ+ E+ ++++ M W + ++ K + EK E E++REQ+ K
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW--EQEEKMREQEEKMREQEEK 668
Score = 51.2 bits (121), Expect = 1e-06
Identities = 63/336 (18%), Positives = 144/336 (42%), Gaps = 29/336 (8%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
W + ++ EQ +++EE E R+ E R+ +++ E E ER++ ++
Sbjct: 341 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400
Query: 91 LRKEERSWEQKLEEMRKKEKSM------PWNVDTLSKDG---FSKSMVNTKPEKTEEDSE 141
+R+EE + ++ E+M+K+E++M W L + + + + + EK E E
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 142 EVREQKHKTFVEK--YEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEV 199
++R+Q+ EK + ++ + W+ +K + +E +W D +
Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER----MWEQDERL 516
Query: 200 EEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAF 259
EK M + + + E K+ + + + ++ + + R+ + +E E
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
Query: 260 KERVRGRAKLRIEKAMKEYEEE--ERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQML 317
+E+ E+ M+E EE+ E+++++ E E + E+ +K ++ ++ +
Sbjct: 577 REQ---------EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 318 QDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKE 353
Q+ M + K Q + +W K E +E
Sbjct: 628 QEQEEMMWEQEEKMQEQ---EEKMWEQEEKMREQEE 660
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/144 (23%), Positives = 71/144 (49%), Gaps = 15/144 (10%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
WR + R+ E +E+EE + +R+ + + KEL E E ++L+ + +Q
Sbjct: 258 WRQEERLREQEGKMREQEE------KMRRQEKRLREQEKELREQEKELREQKKLREQEEQ 311
Query: 91 LRK-EERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHK 149
+++ EE+ WEQ+ E+MR++E+ M + L + + + + +K + E + EQ +
Sbjct: 312 MQEQEEKMWEQE-EKMREQEEKMWRQEERLWE---QEKQMREQEQKMRDQEERMWEQDER 367
Query: 150 TFVEKYEKQIKHFGMLRRWDDSQK 173
EK+ + + W+ +K
Sbjct: 368 L----REKEERMREQEKMWEQEEK 387
Score = 39.3 bits (90), Expect = 0.006
Identities = 65/357 (18%), Positives = 147/357 (41%), Gaps = 51/357 (14%)
Query: 18 ETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELE---VA 74
E + N T + ++ E++ + EK E+ +E KRK+ + L +++ +
Sbjct: 174 ELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQ 233
Query: 75 EGGKAELERLQAEAQQLRK-EERSWEQKL-------------EEMRKKEKSMPWNVDTLS 120
E + E L+ + +++RK EE+ W Q+ E+MR++EK + L
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR 293
Query: 121 KDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRR----WDDSQKYLS 176
+ K + K K E E+++EQ+ K + ++ + + + M R+ W+ ++
Sbjct: 294 EQ--EKELREQK--KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 349
Query: 177 DNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQ 236
+ +E +W D + EK M + + + E + ++ + R
Sbjct: 350 QEQKMRDQEER----MWEQDERLREKEERMRE-------QEKMWEQEEKMQEEERI---- 394
Query: 237 FFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVE 296
R+ + +E E +E+ K E+ M E EE+E +++ P + +
Sbjct: 395 ---------REREKKMREEEETMREQEEKMQKQ--EENMWEQEEKEWQQQRLPEQKEKLW 443
Query: 297 VYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKE 353
E + E+ +K ++ ++ Q+ + + + R + +W K + ++
Sbjct: 444 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Score = 37.0 bits (84), Expect = 0.029
Identities = 28/109 (25%), Positives = 52/109 (47%), Gaps = 17/109 (15%)
Query: 6 VWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRG----CRECKRKV 61
+W+ E +++E W + ++ E+ +E+EE +G RE + K+
Sbjct: 634 MWEQEEKMQEQEEK----------MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Query: 62 AECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEK 110
+ K++E E G+ E + E + +EE+ W Q EEMR+KE+
Sbjct: 684 QGQEEKMREQEEKMRGQEE-KMWGQEEKMWGQEEKMWGQ--EEMREKEE 729
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 49.7 bits (117), Expect = 4e-06
Identities = 53/258 (20%), Positives = 117/258 (45%), Gaps = 30/258 (11%)
Query: 31 WRHQARVERMEQFQKEKE---ELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAE 87
WR + ++ E+ ++KE E + R+ + KV + K++E E E + + E++ +
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE--EKIREQEEKMWRQ 536
Query: 88 AQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGF--SKSMVNTKPEKTEEDSEEVRE 145
+++R++E W ++ E+M ++EK +D + + + EK E++RE
Sbjct: 537 EEKIREQEEMWREE-EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 146 QKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCAL 205
Q+ K E+ EK K +R + ++ + + + E+ + E EEK
Sbjct: 596 QEEKR-QEQEEKMWKQEEKIR---EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
Query: 206 MEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRG 265
E+ + E + ++ +RQ KI+ +++ E +E++R
Sbjct: 652 QEEK---------MCEQEEKMQEQEETMWRQ-EEKIREQEKKIREQ--------EEKIRE 693
Query: 266 RAKLRIEKAMKEYEEEER 283
+ ++ E+ K +E+EE+
Sbjct: 694 QEEMMQEQEEKMWEQEEK 711
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/128 (26%), Positives = 67/128 (52%), Gaps = 14/128 (10%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAE--- 87
WR + +++ E+ +E+EE RE + K+ E + K++ E K E R Q E
Sbjct: 303 WRQEEKIQEWEEKIQEQEE---KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359
Query: 88 --AQQLRKEERSWEQKLEEMRKKEKSMPW----NVDTLSKDGFSKSMVNTKPEKTEEDSE 141
+++R++E +K E+MR++E+ M W + L + + + + EK +E+ E
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMM-WEKEEKIRELEEKMHEQEKIREQEEKRQEE-E 417
Query: 142 EVREQKHK 149
++REQ+ +
Sbjct: 418 KIREQEKR 425
Score = 45.4 bits (106), Expect = 8e-05
Identities = 40/157 (25%), Positives = 71/157 (45%), Gaps = 15/157 (9%)
Query: 18 ETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGG 77
E + N T + ++ E+++ + EK E+ +E KRK+ + L +
Sbjct: 208 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ------- 260
Query: 78 KAELERLQAEAQQLRKEERSWEQKLE-EMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKT 136
++LQAEA L KE +S KL+ ++ + E N K + + EK
Sbjct: 261 ----QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316
Query: 137 EEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQK 173
+E E++REQ+ K E+ EK + M+ W+ +K
Sbjct: 317 QEQEEKIREQEEK-IREQEEKMRRQEEMM--WEKEEK 350
Score = 42.4 bits (98), Expect = 7e-04
Identities = 53/261 (20%), Positives = 114/261 (43%), Gaps = 37/261 (14%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVA--EGGKAELERLQAE 87
R +A++ R E+ +E+EE RE ++K+ + K+ E E E + E E + +
Sbjct: 425 RQEQEAKMWRQEEKIREQEEK---IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 481
Query: 88 AQQLRKEERSWEQK-----LEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEE 142
+++ ++E W QK EE +K++ W + ++ + + + EK E+
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE--QEEKIREQEEKMWRQEEK 539
Query: 143 VREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEK 202
+REQ+ E + ++ K + W++ ++ ++ EE E EEK
Sbjct: 540 IREQE-----EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR---------EQEEK 585
Query: 203 CALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKER 262
E+ I E + + ++Q KI+ + + E +++ +E+
Sbjct: 586 VWRQEEK---------IREQEEKRQEQEEKMWKQ-EEKIREQEEKIQEQ-EEKIREQEEK 634
Query: 263 VRGRAKLRIEKAMKEYEEEER 283
+R + ++ E+ K E+EE+
Sbjct: 635 IREQEEMTQEQEEKMGEQEEK 655
Score = 40.8 bits (94), Expect = 0.002
Identities = 59/261 (22%), Positives = 118/261 (45%), Gaps = 56/261 (21%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
W + ++ R E+ EKEE R + + E + K++ELE E E+++ + ++
Sbjct: 359 WEKEEKMRRQEEMMWEKEE---KMRRQEEMMWEKEEKIRELEEK---MHEQEKIREQEEK 412
Query: 91 LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKT 150
++EE+ EQ E R+++++ W + EK E E++REQ+ K
Sbjct: 413 RQEEEKIREQ---EKRQEQEAKMWR----------------QEEKIREQEEKIREQEKKM 453
Query: 151 FVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVA 210
+ + E++I +R + Q+ EE +W EEK E++
Sbjct: 454 W--RQEEKIHEQEKIREEEKRQEQ---------EE------MW----RQEEKIHEQEEIW 492
Query: 211 HQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKL- 269
Q M E + ++ +RQ KI+ + + E +++ +E++R + ++
Sbjct: 493 RQKEKMH---EQEEKIRKQEEKVWRQ-EEKIREQEEKIREQ-EEKMWRQEEKIREQEEMW 547
Query: 270 RIEKAMKE----YEEEERKKR 286
R E+ M E +EEE+R+++
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQ 568
Score = 37.4 bits (85), Expect = 0.022
Identities = 23/81 (28%), Positives = 47/81 (58%), Gaps = 6/81 (7%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
WR + ++ E+ +E+EE RE + + E + K+ E E E + E++Q + ++
Sbjct: 671 WRQEEKIREQEKKIREQEEK---IREQEEMMQEQEEKMWEQE--EKMCEQEEKMQEQEEK 725
Query: 91 LRK-EERSWEQKLEEMRKKEK 110
+R+ EE+ WEQ++ +++EK
Sbjct: 726 MRRQEEKMWEQEVRLRQQEEK 746
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 49.7 bits (117), Expect = 4e-06
Identities = 62/259 (23%), Positives = 112/259 (43%), Gaps = 32/259 (12%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQ 89
R + + E+ Q+E+E+L R RE KR+ E +R+ +E E + Q E Q
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREERE-KRRRQELERQYREEEEVQ---------QEEEQ 1152
Query: 90 QLRKE-ERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKH 148
LR+E E+ Q+LE ++E+ + + L ++ K + + EE EE++ QK
Sbjct: 1153 LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE--EELQRQKR 1210
Query: 149 KTFVEKYEKQIKHFGMLRRWD-DSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALME 207
K ++Y + + + +W+ + + + DN ++C E E+ L +
Sbjct: 1211 K---QRYRDEDQRSDLKWQWEPEKENAVRDNK------------VYCKGRENEQFRQLED 1255
Query: 208 QVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRA 267
Q + L + R R+ + + DR + E E E KE R
Sbjct: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERR---RWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Query: 268 KLRIEKAMKEYEEEERKKR 286
K + EK + E EE+++R
Sbjct: 1313 KSQEEKQLLREEREEKRRR 1331
Score = 47.4 bits (111), Expect = 2e-05
Identities = 66/283 (23%), Positives = 120/283 (42%), Gaps = 53/283 (18%)
Query: 11 EVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQ--RKL 68
++ +E+E + R + + EQ Q+E+E+L R RE +R+ + RK
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Query: 69 KELEVAE----GGKAELERLQAEAQQLRKEE---RSWEQKLEEMRKKEKSMPWNVDTLSK 121
K+L+ E G + E R Q ++ R+EE + EQ L E R+K + W K
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Query: 122 DGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181
D E +E+ + +RE++ K +++ E+Q + + ++ + L
Sbjct: 1024 D-----------ELQQEEEQLLREEREKRRLQERERQYR---------EEEELQQEEEQL 1063
Query: 182 VCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKI 241
+ EE E + L Q + + Q E + L+ +P RQ
Sbjct: 1064 LGEER-----------ETRRRQELERQYRKEEELQQ---EEEQLLREEPEKRRRQ----- 1104
Query: 242 KTADRQYMEGFNDELEAFKERV--RGRAKLRIEKAMKEYEEEE 282
+RQ E +EL+ +E++ R K R ++ ++Y EEE
Sbjct: 1105 -ERERQCRE--EEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Score = 44.7 bits (104), Expect = 1e-04
Identities = 58/264 (21%), Positives = 120/264 (45%), Gaps = 61/264 (23%)
Query: 36 RVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEE 95
R ER +F++E+++L R RE K E Q + +ELE + +L R + E +QLR++E
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL-RQETEQEQLRRQE 1744
Query: 96 RSW----------EQKLEEMRKKEKSMPWNVDT-LSKDGFSKSMVNTKPEKTEEDSEEVR 144
R E++ +++R++E+ + + L ++ + + + + ++ + E++R
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804
Query: 145 EQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCA 204
+++ + + ++ K+ RW++ Q L++EE+
Sbjct: 1805 QEREEQQLRPQQRDGKY-----RWEEEQ------------------------LQLEEQ-- 1833
Query: 205 LMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVR 264
EQ Q Q+ E QF T+ K+ R+ E + +E + K R
Sbjct: 1834 --EQRLRQERDRQYRAE-------------EQFATQEKSR-REEQELWQEEEQ--KRRQE 1875
Query: 265 GRAKLRIEKAMKEYEEEERKKRLG 288
KLR E ++ +EE+R +++G
Sbjct: 1876 RERKLREEHIRRQQKEEQRHRQVG 1899
Score = 44.3 bits (103), Expect = 2e-04
Identities = 76/324 (23%), Positives = 130/324 (40%), Gaps = 34/324 (10%)
Query: 14 DDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEV 73
++ +E +T FR Q ER EQ ++E DR RE + + E RK E E
Sbjct: 1323 EEREEKRRRQETDRKFREEEQLLQEREEQ-PLRRQERDRKFREEELRHQEQGRKFLEEEQ 1381
Query: 74 AEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKP 133
+ + E QQLR +ER EQ+L + R D ++ + +
Sbjct: 1382 RLRRQERERKFLKEEQQLRCQER--EQQLRQDR----------DRKFREEEQQLSRQERD 1429
Query: 134 EKTEEDSEEVREQ----------------KHKTFVEKYE-KQIKHFGMLRRWDDSQKYLS 176
K E+ ++VR Q +H+ F E+ + Q + L R + +K+L
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLE 1489
Query: 177 DNVHLVCEE-TANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFR 235
+ L +E + E E K EQ H+ + L+ + L+ R R
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 236 QFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPV 295
+ K + + + +E + ++ R R K R+E+ +E+ERK L
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQE-RDR-KFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 296 EVYESLPEELQKCFDVKDVQMLQD 319
E + L +E + F +D Q+LQ+
Sbjct: 1608 EGQQQLRQERDRKFR-EDEQLLQE 1630
Score = 42.4 bits (98), Expect = 7e-04
Identities = 32/136 (23%), Positives = 70/136 (51%), Gaps = 8/136 (5%)
Query: 32 RHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQL 91
R + ER +Q K +E+ +R ++ +R+ E R+ + L+ E + +RL+ E ++
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQE--RREQRLKREEEEERLEQRLKREHEEE 679
Query: 92 RKEERSWEQKLEEMRKKEKSM--PWNVDTLSKDGFSKSMVNTKPEKTE----EDSEEVRE 145
R+E+ E++ E+ R++ KS W S+ +S V ++P K E +E +
Sbjct: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKR 739
Query: 146 QKHKTFVEKYEKQIKH 161
++ ++ ++ E++ H
Sbjct: 740 RRRESELQWQEEERAH 755
Score = 42.4 bits (98), Expect = 7e-04
Identities = 56/267 (20%), Positives = 123/267 (46%), Gaps = 33/267 (12%)
Query: 34 QARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQ-AEAQQLR 92
Q +R ++ +E+++L R RE KR+ E RK +E E + LQ E Q LR
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE---------EEQLLQEREEQPLR 1354
Query: 93 KEERSWEQKLEEMRKKEKSMPW--NVDTLSKDGFSKSMVNTKPE-KTEEDSEEVREQKHK 149
++ER + + EE+R +E+ + L + + + + + + +E +++R+ + +
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 150 TFVEKYEKQI----------KHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEV 199
F E+ E+Q+ + +RR + +K+L + L E + + E
Sbjct: 1415 KFREE-EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Query: 200 EEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAF 259
EE +Q+ Q +F+ E + + + FR+ + + +R+++E E +
Sbjct: 1474 EE-----QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE----EEQQL 1524
Query: 260 KERVRGRAKLRIEKAMKEYEEEERKKR 286
+ R R L+ E+ ++ E +++++
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/280 (21%), Positives = 124/280 (44%), Gaps = 36/280 (12%)
Query: 15 DEDETHPNIDTASLFRWRH-----QARVERMEQFQKEKEELDRGCRECKRKVAECQRKLK 69
+E+E ++ L R R Q R+ R +Q ++++EE R +E +R+ E + + +
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 70 ELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMV 129
E + + + ER + QQLR+E+ E++ E+ ++E+ L ++ +
Sbjct: 333 ERREQQLRREQEERRE---QQLRREQE--EERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 130 NTKPEKTEEDSEEVR--EQKHKTFVEKYEKQIKHFGMLRRWDD----SQKYLSDNVHLVC 183
+ E+ +++R +Q + + E+Q++ LRR + QK+ +
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 184 EETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKT 243
+ W L+ EE+ EQ + + LK D R+ + K++
Sbjct: 448 KREQEERRDW---LKREEETERHEQERRK-----------QQLKRDQEEERRERWLKLEE 493
Query: 244 ADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEER 283
+R+ ++ E ++++R + R E+ +K EEEER
Sbjct: 494 EERR------EQQERREQQLRREQEERREQRLKRQEEEER 527
Score = 40.0 bits (92), Expect = 0.003
Identities = 66/293 (22%), Positives = 123/293 (41%), Gaps = 61/293 (20%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKR-KVAECQRKLKELEVAEGGKAELERLQAEA 88
R R ++R+ + Q+Q E E R + R + E QR+ +E E E R +
Sbjct: 694 RERIKSRIPKW-QWQLESEADARQSKVYSRPRKQEGQRRRQEQE-------EKRRRRESE 745
Query: 89 QQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSE----EVR 144
Q ++EER+ Q+ EE ++++ + W + S+ G + ++ +P E+ E R
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG--RQRLSARPPLREQRERQLRAEER 803
Query: 145 EQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYL-------------- 190
+Q+ + F+ + E++ + R + ++L + L E A L
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863
Query: 191 --------VIWCIDLEVEE---------KCALMEQVAHQTIVMQFILELAKSLKVDPRAC 233
W LE E K AL EQ+ + Q + E + L+ + R
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE---QQLLQEEEEELQREEREK 920
Query: 234 FRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKR 286
R+ + +RQY E ++L+ +E++ LR E+ + +E ER+ R
Sbjct: 921 RRR-----QEQERQYRE--EEQLQQEEEQL-----LREEREKRRRQERERQYR 961
Score = 40.0 bits (92), Expect = 0.003
Identities = 57/268 (21%), Positives = 112/268 (41%), Gaps = 29/268 (10%)
Query: 41 EQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQ 100
E+ Q ++E DR RE + + E +RK E E + + E QQLR++ER ++
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 101 KLEEMRK------------------KEKSMPWNVD---TLSKDGFSKSMVNTKPEKTEED 139
+ + RK +E+ + ++ ++ K M + + + +E
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEG 1609
Query: 140 SEEVREQKHKTFVEKYE-KQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLE 198
+++R+++ + F E + Q + L R + +K+L + L +E L D +
Sbjct: 1610 QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL-RHDRDRK 1668
Query: 199 VEEKCALMEQVAHQTIVMQ----FILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFND 254
E+ L+++ Q + Q E + L+ R R+F + + RQ +E
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE--RKFLQEEQQLRRQELERKFR 1726
Query: 255 ELEAFKERVRGRAKLRIEKAMKEYEEEE 282
E E ++ R E+ K EEE+
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Score = 38.5 bits (88), Expect = 0.010
Identities = 54/269 (20%), Positives = 115/269 (42%), Gaps = 25/269 (9%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQ 89
RW ER EQ ++ +++L R E + + + Q + + L+ + +L R Q E +
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 90 QL---RKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQ 146
+ R+EE+ EQ+ E R K + +D K + ++ + + EE EQ
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEE------RRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 147 KHKTF-VEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLE------- 198
+ K VE+ E++ + L+R + ++ + +E + E
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK 660
Query: 199 -VEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELE 257
EE+ L +++ + + ELA+ + R +IK+ ++ E +
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARE-------RIKSRIPKWQWQLESEAD 713
Query: 258 AFKERVRGRAKLRIEKAMKEYEEEERKKR 286
A + +V R + + + ++ +EE+R++R
Sbjct: 714 ARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
Score = 38.1 bits (87), Expect = 0.013
Identities = 34/173 (19%), Positives = 77/173 (44%), Gaps = 17/173 (9%)
Query: 15 DEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVA 74
+E++ + L R ++ EQ + E+EE +E RK E ++ +E E
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 75 EGGKAELERLQAEAQQLRKEERS-------------WEQKLEEMRKKEKSMPWNVDTLSK 121
+ E +R E +QLR+E WE++ ++ ++E+ + D +
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYR 1846
Query: 122 DGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKY 174
++ T+ + E+ E +E++ K E+ E++++ + R+ + Q++
Sbjct: 1847 ---AEEQFATQEKSRREEQELWQEEEQKRRQER-ERKLREEHIRRQQKEEQRH 1895
Score = 36.6 bits (83), Expect = 0.038
Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 16/134 (11%)
Query: 39 RMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKA--ELERLQAEAQQLRKEE- 95
R E+ Q+ E DR E + +R+ +E E+AEG + + ERL+ +Q R EE
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
Query: 96 ----RSWEQKLEEMRKKEKSMPWNVDTLSKDGF-------SKSMVNTKPEKTEEDSEEVR 144
+ W+++ E R+ E+ + + F + ++ + + EE ++ R
Sbjct: 174 WRQRQEWQER--EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR 231
Query: 145 EQKHKTFVEKYEKQ 158
E++ + F E+ EK+
Sbjct: 232 ERQDRVFQEEEEKE 245
Score = 36.2 bits (82), Expect = 0.050
Identities = 61/268 (22%), Positives = 124/268 (46%), Gaps = 32/268 (11%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEA- 88
R + Q ER++Q + +++L R E + ++ + + + K LE E + L+R Q E
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEE-KRLE-QERREQRLKREQEERR 575
Query: 89 -QQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQ- 146
Q L++EE +Q+L+ R++E+ + + + + + K EE EE R+Q
Sbjct: 576 DQLLKREEERRQQRLK--REQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 147 -KHKTFVEKYEKQIKHFGMLRR-----WDDSQKYLSDNVHLVCEETANYLVIWCIDLEVE 200
K + E+ ++Q++ RR ++ ++ L + EE +L E
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ-----ELAEE 688
Query: 201 EKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFK 260
E+ E++ + Q+ LE + D R +K+ + R+ EG E +
Sbjct: 689 EQEQARERIKSRIPKWQWQLE----SEADARQ------SKVYSRPRK-QEGQRRRQEQEE 737
Query: 261 ERVRGRAKLR---IEKAMKEYEEEERKK 285
+R R ++L+ E+A ++ +EEE+++
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRR 765
Score = 35.0 bits (79), Expect = 0.11
Identities = 29/130 (22%), Positives = 65/130 (50%), Gaps = 4/130 (3%)
Query: 32 RHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQA-EAQQ 90
+ Q R ER ++ +E+EE + RE + E + + +E + + E E+L+ E Q+
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE 285
Query: 91 LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKT 150
LR+E + EQ+ + +R++++ + + + + E+ E+ E +Q +
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER---REQQERREQQEERREQQLRRE 342
Query: 151 FVEKYEKQIK 160
E+ E+Q++
Sbjct: 343 QEERREQQLR 352
Score = 33.9 bits (76), Expect = 0.25
Identities = 36/159 (22%), Positives = 72/159 (45%), Gaps = 32/159 (20%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAEL--------- 81
W Q R + ++ Q+E+E+L R RE KR++ E +R+ +E E + + +L
Sbjct: 1016 WERQYR--KKDELQQEEEQLLREERE-KRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Query: 82 -----------ERLQAEAQQLRKEE---RSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKS 127
E LQ E +QL +EE R +++ + R++E+ L ++ +
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 128 MVNTKPEKTEEDSEE------VREQKHKTFVEKYEKQIK 160
+ + EE+ + +RE+ K ++ E+Q +
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Score = 33.5 bits (75), Expect = 0.32
Identities = 27/133 (20%), Positives = 63/133 (47%), Gaps = 7/133 (5%)
Query: 28 LFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAE 87
L R + R E+ +Q ++ ++ + + E + + E + +E ++ E LQ E
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE 274
Query: 88 AQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQK 147
+QLRK ER +E+R++ + L ++ + + + +E+ E +E++
Sbjct: 275 EEQLRKLER------QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 148 HKTFVEKYEKQIK 160
+ E+ E+Q++
Sbjct: 329 EQQ-EERREQQLR 340
Score = 32.7 bits (73), Expect = 0.55
Identities = 51/282 (18%), Positives = 120/282 (42%), Gaps = 35/282 (12%)
Query: 14 DDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVA----ECQRKLK 69
+ E+E H R + E + K +EE +R +E +++ E +R+ +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 70 ELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMV 129
L++ E + E + + QQLR+E+ E++ + ++++E+ S+ +
Sbjct: 488 WLKLEEEERREQQ--ERREQQLRREQE--ERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 130 NTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANY 189
+ + + + E+ EQ+ + K E++ + +L+R ++ ++
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR-------------- 589
Query: 190 LVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKV---DPRACFRQFFTKIKTADR 246
+ E EE+ +EQ + V + E + ++ +P RQ K + +
Sbjct: 590 -----LKREQEER---LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 247 QYMEGFNDELEAFKER--VRGRAKLRIEKAMKEYEEEERKKR 286
+ + E + +E+ R + R+E+ +K EEER+++
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 49.3 bits (116), Expect = 6e-06
Identities = 74/348 (21%), Positives = 148/348 (42%), Gaps = 37/348 (10%)
Query: 18 ETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGG 77
E + N T + ++ E+++ + EK E+ +E KRK+ + L +
Sbjct: 208 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ------- 260
Query: 78 KAELERLQAEAQQLRKEERSWEQKLE-EMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKT 136
++LQAEA L KE +S KL+ ++ + E N K + + EK
Sbjct: 261 ----QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316
Query: 137 EEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKY-LSDNVHLVCEETANYL--VIW 193
+E E++REQ+ K E+ EK + M+ W+ +K + + EE L ++W
Sbjct: 317 QEQEEKIREQEEK-IREQEEKMRRQEEMM--WEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 194 CID---LEVEEKCALMEQVAHQTIVMQFILELAKSLK-VDPRACFRQFFTKIKTADRQYM 249
+ E+EEK E++ Q Q ++ + K + A + KI+ + +
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 250 EGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCF 309
E ++ +E++ + K+R E+ +E EE R++ + + E + + +K
Sbjct: 434 EQ-EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE-------EKIREQEEIWRQKEKMH 485
Query: 310 DVKDVQMLQDAI----SKMDPTDAKYHMQRCIDSGLWVPNSKASEAKE 353
+ + ++ ++ + KM + K Q + +W K E +E
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQ---EEKMWRQEEKIREQEE 530
Score = 42.7 bits (99), Expect = 5e-04
Identities = 63/288 (21%), Positives = 127/288 (44%), Gaps = 46/288 (15%)
Query: 31 WRHQARVERMEQFQKEKEE----LDRGCRECKRKVAECQRKLKELE---VAEGGKAELER 83
W + ++ R E+ EKEE L+ E + K+ E + K+ E E E + E E+
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Query: 84 LQAEAQQLRKEERSWEQ------KLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTE 137
++ + ++ +E + W Q + E++R++EK M + + + K K ++ E
Sbjct: 405 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ--EKIREEEKRQEQE 462
Query: 138 E---------DSEEVREQKHKTF-VEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETA 187
E + EE+ QK K EK KQ + + W +K + D + E+
Sbjct: 463 EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEE-----KVWRQEEK-MHDQEEKIREQEE 516
Query: 188 NYLVIWCIDLEVEEKCALM----EQVAHQTIVMQFILEL--AKSLKVDPRACFRQFFTKI 241
+W + ++ E+ + E++ Q +MQ E + K+ + R+ KI
Sbjct: 517 K---MWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI 573
Query: 242 KTAD---RQYMEGFNDELEAF---KERVRGRAKLRIEKAMKEYEEEER 283
+ + R+ E ++ E +E++R + ++ E+ K +E+EE+
Sbjct: 574 REQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEK 621
Score = 34.3 bits (77), Expect = 0.19
Identities = 25/98 (25%), Positives = 51/98 (52%), Gaps = 17/98 (17%)
Query: 30 RWRHQARVERMEQFQKEKEELDRG----CRECKRKVAECQRKLKELEVAEGGKAEL---- 81
+ + Q ++ R E+ +E+EE R RE + K+ E + K++E E + E
Sbjct: 559 KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618
Query: 82 --------ERLQAEAQQLRK-EERSWEQKLEEMRKKEK 110
E++Q + +++R+ EE+ WEQ++ +++EK
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/170 (24%), Positives = 75/170 (44%), Gaps = 18/170 (10%)
Query: 18 ETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGG 77
E + N T + ++ E+++ + EK E+ +E KRK+ + L +
Sbjct: 196 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ------- 248
Query: 78 KAELERLQAEAQQLRKEERSWEQKLE-EMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKT 136
++LQAEA L KE +S KL+ ++ + E N K + + + EK
Sbjct: 249 ----QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKI 304
Query: 137 EEDSEEVREQKHK------TFVEKYEKQIKHFGMLRRWDDSQKYLSDNVH 180
+E E++REQ+ K EK EK + M+ ++ + L + +H
Sbjct: 305 QEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354
Score = 47.4 bits (111), Expect = 2e-05
Identities = 33/130 (25%), Positives = 70/130 (53%), Gaps = 6/130 (4%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
W + ++ R E+ EKEE R E + + + + ++ + E + + +R + EA+
Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 385
Query: 91 LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKT 150
R+EE+ EQ+ E++R++E+ M + K G + + + E+ +E E++R Q+ K
Sbjct: 386 WRQEEKIREQE-EKIREQEEMMQ---EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK- 440
Query: 151 FVEKYEKQIK 160
+ + EK+I+
Sbjct: 441 -IREQEKKIR 449
Score = 44.7 bits (104), Expect = 1e-04
Identities = 56/269 (20%), Positives = 121/269 (44%), Gaps = 44/269 (16%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAEC----QRKLKELEVAEGGK----AELE 82
WR + +++ E+ +E+EE R E R+ E + K++ E K ELE
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 350
Query: 83 RLQAEAQQLRKEE--RSWEQKL--EEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEE 138
E +++R++E R E+K+ +E R+++++ W + ++ + + + E +E
Sbjct: 351 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE--QEEKIREQEEMMQE 408
Query: 139 DSEEVREQKHKTFVEKYEKQIKHFGMLRRWD---DSQKYLSDNVHLVCEETANYLVIWCI 195
E++ EQ+ K + ++ E Q + M R+ + + +K + + + E+ +
Sbjct: 409 QEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE-------M 461
Query: 196 DLEVEEKCALME-QVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFND 254
E EEK E ++ Q MQ + R+ KI+ +++ E
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQ-----------EQEEKMRRQEEKIREQEKKIREQ--- 507
Query: 255 ELEAFKERVRGRAKLRIEKAMKEYEEEER 283
+E++R + ++ E+ K +E+EE+
Sbjct: 508 -----EEKIREQEEMMQEQEEKMWEQEEK 531
Score = 34.7 bits (78), Expect = 0.15
Identities = 29/116 (25%), Positives = 56/116 (48%), Gaps = 12/116 (10%)
Query: 34 QARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRK 93
Q + E+M + + + E + +E + K+ + K++E E + E R Q E Q +
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ-EQ 521
Query: 94 EERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHK 149
EE+ WEQ+ E+M ++E+ M + + + + EK E +R+Q+ K
Sbjct: 522 EEKMWEQE-EKMCEQEEKMQEQEEKMRR----------QEEKMREQEVRLRQQEEK 566
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 47.8 bits (112), Expect = 2e-05
Identities = 35/126 (27%), Positives = 67/126 (53%), Gaps = 14/126 (11%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERS 97
E+ EQ K++E++ E K ++ E + ++ + E G + E ++Q + +Q+RK+E
Sbjct: 321 EQEEQMGKQEEQM----WEQKEQMWEQKEQMWKQEEQMGEQEE--QMQKQEEQVRKQEEQ 374
Query: 98 WEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEK 157
++ E+MRK+E+ M + + G K + + E+ E E++ EQK E+ K
Sbjct: 375 MRKQEEQMRKQEEQMRKQEEQM---GEQKEQMGEQKEQMREQEEQMGEQK-----EQMRK 426
Query: 158 QIKHFG 163
Q +H G
Sbjct: 427 QEEHMG 432
Score = 43.1 bits (100), Expect = 4e-04
Identities = 30/130 (23%), Positives = 71/130 (54%), Gaps = 6/130 (4%)
Query: 32 RHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKE-LEVAEGGKAELERLQAEAQQ 90
+ + +V++ E+ +++EE R E R+ E K KE E E + E+++ + +Q
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
Query: 91 LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKT 150
+R++E ++ E+MR++E+ M + + + K + + E+ + E++ EQ+ +
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGKQEEQMWE---QKEQMWEQKEQMWKQEEQMGEQEEQ- 360
Query: 151 FVEKYEKQIK 160
++K E+Q++
Sbjct: 361 -MQKQEEQVR 369
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/123 (24%), Positives = 67/123 (54%), Gaps = 19/123 (15%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERS 97
E+ EQ QK++E++ E Q + +E ++ E + E++Q + +Q++K+E
Sbjct: 210 EQEEQMQKQEEQMGE---------QEEQMRKQEEQMGE----QEEQVQKQEEQVQKQEEQ 256
Query: 98 WEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEK 157
++ E+MR++E+ M + + K + + E+T E E++REQ+ + + + E+
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLK----QKEQTEQEEQTGEQEEQMREQEEQ--MREQEE 310
Query: 158 QIK 160
Q++
Sbjct: 311 QMR 313
Score = 40.0 bits (92), Expect = 0.003
Identities = 33/131 (25%), Positives = 70/131 (53%), Gaps = 10/131 (7%)
Query: 34 QARVERMEQFQKEKE----ELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQ 89
+ +V E +E+E E + RE + +V E + ++ E E + G+ E E++ + +
Sbjct: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQE-GQMGEQE-EQMGEQEE 213
Query: 90 QLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHK 149
Q++K+E ++ E+MRK+E+ M + + K + V + E+ + E++REQ+ +
Sbjct: 214 QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK---QEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 150 TFVEKYEKQIK 160
E+ E+ +K
Sbjct: 271 -MREQEEQMLK 280
Score = 39.3 bits (90), Expect = 0.006
Identities = 26/85 (30%), Positives = 50/85 (58%), Gaps = 4/85 (4%)
Query: 31 WRHQARV-ERMEQFQKEKEELDRGCRECKRKVAECQRKLKE--LEVAEGGKAELERLQAE 87
W+ + ++ E+ EQ QK++E++ R E RK E RK +E + E + E++ +
Sbjct: 348 WKQEEQMGEQEEQMQKQEEQV-RKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQ 406
Query: 88 AQQLRKEERSWEQKLEEMRKKEKSM 112
+Q+R++E ++ E+MRK+E+ M
Sbjct: 407 KEQMREQEEQMGEQKEQMRKQEEHM 431
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 47.8 bits (112), Expect = 2e-05
Identities = 74/357 (20%), Positives = 148/357 (41%), Gaps = 54/357 (15%)
Query: 18 ETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGG 77
E + N T + ++ E+++ + EK E+ +E KRK+ + L +
Sbjct: 269 ELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ------- 321
Query: 78 KAELERLQAEAQQLRKEERSWEQKLE----------EMRKKEKSMPWNVDTLSKDGFSKS 127
++LQAEA L KE +S KL+ + ++++ W + ++ K
Sbjct: 322 ----QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK- 376
Query: 128 MVNTKPEKTEEDSEEVREQKHK------TFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181
+ + EK E E++REQ+ K EK EK + M+ W+ +K + +
Sbjct: 377 -IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM--WEKEEK-MRRQEEM 432
Query: 182 VCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLK-VDPRACFRQFFTK 240
+ E+ E+EEK E++ Q Q ++ + K + A + K
Sbjct: 433 MWEKEEKI-------RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 485
Query: 241 IKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYES 300
I+ + + E +++ +E++ + K+R E+ +E EE R++ + + E
Sbjct: 486 IREQEEKIREQ-EEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE-------EKIREQEE 537
Query: 301 LPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQ----RCIDSGLWVPNSKASEAKE 353
+ + +K + ++ Q+ KM + K H Q R + +W K E +E
Sbjct: 538 IWRQKEKIHEQEEKIRKQE--EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/161 (23%), Positives = 83/161 (51%), Gaps = 21/161 (13%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
WR + ++ E+ +E+EE + R+ + K+ E Q K++E E + E E + + ++
Sbjct: 480 WRQEEKIREQEEKIREQEE--KMWRQ-EEKIHE-QEKIRE----EEKRQEQEEMWRQEEK 531
Query: 91 LRKEERSWEQK------LEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVR 144
+R++E W QK E++RK+E+ M W + D + + + EK E++R
Sbjct: 532 IREQEEIWRQKEKIHEQEEKIRKQEEKM-WRQEEKMHD--QEEKIREQEEKVWRQEEKIR 588
Query: 145 EQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEE 185
EQ+ K + + E++I+ + + + ++ + + +CE+
Sbjct: 589 EQEEK--IREQEEKIREQEEMTQ--EQEEKMGEQEEKMCEQ 625
Score = 45.1 bits (105), Expect = 1e-04
Identities = 31/149 (20%), Positives = 80/149 (53%), Gaps = 13/149 (8%)
Query: 31 WRHQARVERMEQFQKEKEELDRG----CRECKRKVAECQRKLKELEVAEGGKAELERLQA 86
WR + ++ E+ +E+EE R +E + K+ E + K+ E E E + + E+++
Sbjct: 581 WRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE--EKMQEQEEKMRR 638
Query: 87 EAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQ 146
+ +++R++E+ ++ E++R++E+ M + + + + + + EK +E E++R Q
Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE---QEEKMCEQEEKMQEQEEKMRRQ 695
Query: 147 KHKTFVEKYEKQIKHFGMLRRWDDSQKYL 175
+ K +E++++ + + Q++L
Sbjct: 696 EEK----MWEQEVRLRQQEEKMQEHQEHL 720
Score = 43.9 bits (102), Expect = 2e-04
Identities = 29/133 (21%), Positives = 71/133 (53%), Gaps = 10/133 (7%)
Query: 31 WRHQARVERMEQFQKEKE---ELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAE 87
WR + ++ E+ ++KE E + R+ + K+ + K+ + E E + + E++ +
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE--EKIREQEEKVWRQ 583
Query: 88 AQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQK 147
+++R++E ++ E++R++E+ + K G + + + EK +E E++R Q+
Sbjct: 584 EEKIREQEEKIREQEEKIREQEE---MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 148 HKTFVEKYEKQIK 160
K + + EK+I+
Sbjct: 641 EK--IREQEKKIR 651
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 47.8 bits (112), Expect = 2e-05
Identities = 71/368 (19%), Positives = 166/368 (45%), Gaps = 46/368 (12%)
Query: 16 EDETHPNIDTASL-FRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVA 74
ED+ N + +L R QA +E+ + Q+ +L+R +E K + + Q + ++LE+
Sbjct: 351 EDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLEL- 409
Query: 75 EGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKE----KSMPWN-------VDTLSKDG 123
+ +LE+ Q E ++ R+EER E + E K+E + + W ++ +K+
Sbjct: 410 ---EKQLEK-QRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQ 465
Query: 124 FSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQK----YLSDNV 179
++ K + E + E + ++KH+ + + + + + + + K +++
Sbjct: 466 EDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEIT 525
Query: 180 HLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVD--PRACFRQF 237
HL + + ++ + E + ++QV ++ ++ L ++L+ R R
Sbjct: 526 HLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQ 585
Query: 238 FTKIKTADR---QYMEGFNDELEAFKERVRGRAKLRIEKAMK----EYEEEERKKRLGPG 290
+++ R Q ++ FN++L+ +E + + +L+ +K+M+ + +E+ERK
Sbjct: 586 LDEVEKETRSKLQEIDIFNNQLKELRE-IHNKQQLQKQKSMEAERLKQKEQERK------ 638
Query: 291 GLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASE 350
+ E EE Q+ +D Q L+ + ++ R + + ++ +
Sbjct: 639 ----IIELEKQKEEAQRRAQERDKQWLEHV-----QQEDEHQRPRKLHEEEKLKREESVK 689
Query: 351 AKEGEEAG 358
K+GEE G
Sbjct: 690 KKDGEEKG 697
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 47.8 bits (112), Expect = 2e-05
Identities = 71/368 (19%), Positives = 166/368 (45%), Gaps = 46/368 (12%)
Query: 16 EDETHPNIDTASL-FRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVA 74
ED+ N + +L R QA +E+ + Q+ +L+R +E K + + Q + ++LE+
Sbjct: 351 EDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLEL- 409
Query: 75 EGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKE----KSMPWN-------VDTLSKDG 123
+ +LE+ Q E ++ R+EER E + E K+E + + W ++ +K+
Sbjct: 410 ---EKQLEK-QRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQ 465
Query: 124 FSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQK----YLSDNV 179
++ K + E + E + ++KH+ + + + + + + + K +++
Sbjct: 466 EDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIESTNKSRELRIAEIT 525
Query: 180 HLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVD--PRACFRQF 237
HL + + ++ + E + ++QV ++ ++ L ++L+ R R
Sbjct: 526 HLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELARQHLRDQ 585
Query: 238 FTKIKTADR---QYMEGFNDELEAFKERVRGRAKLRIEKAMK----EYEEEERKKRLGPG 290
+++ R Q ++ FN++L+ +E + + +L+ +K+M+ + +E+ERK
Sbjct: 586 LDEVEKETRSKLQEIDIFNNQLKELRE-IHNKQQLQKQKSMEAERLKQKEQERK------ 638
Query: 291 GLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASE 350
+ E EE Q+ +D Q L+ + ++ R + + ++ +
Sbjct: 639 ----IIELEKQKEEAQRRAQERDKQWLEHV-----QQEDEHQRPRKLHEEEKLKREESVK 689
Query: 351 AKEGEEAG 358
K+GEE G
Sbjct: 690 KKDGEEKG 697
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 47.4 bits (111), Expect = 2e-05
Identities = 59/259 (22%), Positives = 118/259 (45%), Gaps = 24/259 (9%)
Query: 33 HQARVERMEQFQ--KEKEELDRGCR---ECKRKVAECQRKL-KELEVAEGGKAELERLQA 86
H+ R+ ME+ + K K E RG R + +RK+A+ RKL K+ E A+L ++
Sbjct: 2019 HEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILK 2078
Query: 87 EAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQ 146
Q+L ++ER Q+ +M K ++++ LS + +K + E D E R +
Sbjct: 2079 ALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIE-------QSKLDIKEWDFSEKRSE 2131
Query: 147 KHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALM 206
K + KQ K +RR + ++ +++ + + + + L+ EE+ +
Sbjct: 2132 LTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVI------LDDEEEGGIE 2185
Query: 207 EQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGR 266
E+ V+ F+ + K R + + + + E F++E+E+ + + +
Sbjct: 2186 EEE-----VIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQ 2240
Query: 267 AKLRIEKAMKEYEEEERKK 285
L E+ + EEEER++
Sbjct: 2241 ESLSSEEEEEREEEEEREE 2259
Score = 40.0 bits (92), Expect = 0.003
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 14/150 (9%)
Query: 11 EVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKE 70
+V + E E H + + SL +E+ E E+EE E + + + +++E
Sbjct: 2216 QVDEVESEEHFSEEMESLLD-----ELEKQESLSSEEEE------EREEEEEREEEEVRE 2264
Query: 71 LEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVN 130
E + E E Q E ++ K+++ E+K EE+++KE+ + +S++
Sbjct: 2265 EEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDE 2324
Query: 131 TKPEKTEEDSEEVREQKHKTFVEKYEKQIK 160
+ E++ EEV +K + K EKQ K
Sbjct: 2325 EEEEESCSLEEEVDREKE---ILKKEKQFK 2351
Score = 39.3 bits (90), Expect = 0.006
Identities = 35/156 (22%), Positives = 75/156 (48%), Gaps = 12/156 (7%)
Query: 6 VWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCREC----KRKV 61
VW+++ S +++ + + + +L + E+ +Q +E+ + + KR
Sbjct: 1524 VWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRAR 1583
Query: 62 AECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSK 121
AE +R +E ++A+ E E+L E +QL +EER Q ++ + ++ M K
Sbjct: 1584 AEKKRAQEERKLAQ----EEEKLAQEERQLAQEERKLAQAYVKITQDDREM---AQAEGK 1636
Query: 122 DGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEK 157
+ + + EK +++E++ QK K +K+EK
Sbjct: 1637 FAQKEETLAQRGEKLSQEAEKL-AQKRKKLAKKWEK 1671
Score = 38.5 bits (88), Expect = 0.010
Identities = 42/164 (25%), Positives = 83/164 (50%), Gaps = 17/164 (10%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKA-ELERLQAEA 88
+W AR E E+ K+ +L +KV E ++ + L+ E A ELE L+ +
Sbjct: 1668 KWEKVAREE--EKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDM 1725
Query: 89 QQL--RKEERSWEQ-KLEEMRKK----EKSMPWNVDTLSKD----GFSKSMVNTKPEKTE 137
++L ++EE + E+ KL E +KK E+++ W + LS++ + ++ + EK
Sbjct: 1726 EELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLA 1785
Query: 138 EDSEEVREQKHKTFVEK---YEKQIKHFGMLRRWDDSQKYLSDN 178
+ E++ E++ + ++ EK++K RW +S + L+ N
Sbjct: 1786 QHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKN 1829
Score = 37.4 bits (85), Expect = 0.022
Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 22/152 (14%)
Query: 12 VSDDEDETHPNIDTASLF---RWRHQARVER----MEQFQKEKEELDRGCRECKRKVAEC 64
+ DDE+E + F RWR + +R E+F + +E++ + E
Sbjct: 2175 ILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESE----EHFSEEM 2230
Query: 65 QRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGF 124
+ L ELE + E L +E ++ R+EE E+ EE+R++E+ + K
Sbjct: 2231 ESLLDELE-------KQESLSSEEEEEREEEEEREE--EEVREEEEERKEEEEGEEKQ-V 2280
Query: 125 SKSMVNTKPEKTEEDSEEVREQKHKTFVEKYE 156
K K +K E+ EEV+E K + F EK E
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQE-KEEVFEEKEE 2311
Score = 35.4 bits (80), Expect = 0.085
Identities = 28/150 (18%), Positives = 71/150 (47%), Gaps = 20/150 (13%)
Query: 9 HIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKL 68
+++++ D+ E F + + +R E+ +E E+L + ++ +K + R+
Sbjct: 1620 YVKITQDDREM---AQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREE 1676
Query: 69 KELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKD----GF 124
++L G AE++ + A QK+EE+ ++E+++ W L+++ +
Sbjct: 1677 EKLAKKGGKLAEVKNILA-------------QKVEELPQREQNLDWQEKELAQELEELEW 1723
Query: 125 SKSMVNTKPEKTEEDSEEVREQKHKTFVEK 154
++ K E+ ++ ++ E+K K E+
Sbjct: 1724 DMEELSWKEEELNQEEGKLVEEKKKLAEEE 1753
Score = 29.6 bits (65), Expect = 4.7
Identities = 47/222 (21%), Positives = 91/222 (40%), Gaps = 45/222 (20%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKA----ELERLQAEAQQLRK 93
E+ + K++++L R R+ K+ K +++ E A E+ E + +
Sbjct: 2127 EKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEE 2186
Query: 94 EE------RSWEQKLEEMR---KKEKSMPWNVDTLSKDGFSKSMVN-------------- 130
EE R W ++ E R KEK + S++ FS+ M +
Sbjct: 2187 EEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSE 2246
Query: 131 ---TKPEKTEEDSEEVREQK---------HKTFVEKYEKQIKHFGMLRRWDDSQ---KYL 175
+ E+ E + EEVRE++ + VEK E++ K ++ ++ Q +
Sbjct: 2247 EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVF 2306
Query: 176 SDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQ 217
+ ++ EE L + E EE C+L E+V + +++
Sbjct: 2307 EEKEEIMSEEETESL---SDEEEEEESCSLEEEVDREKEILK 2345
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 47.4 bits (111), Expect = 2e-05
Identities = 36/131 (27%), Positives = 63/131 (48%), Gaps = 4/131 (3%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQ 89
R R + + E+ + +KE+ E + RE + K E + K K+ E E G+ E + E
Sbjct: 77 RKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE-- 134
Query: 90 QLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHK 149
RKEER E++ E RKKE+ K K + + E+ E++ +E ++++
Sbjct: 135 --RKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 150 TFVEKYEKQIK 160
K E++ K
Sbjct: 193 RKERKKERERK 203
Score = 45.1 bits (105), Expect = 1e-04
Identities = 32/136 (23%), Positives = 65/136 (47%), Gaps = 11/136 (8%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERS 97
E+ ++ +KEK+E R +E K + + +RK +E + E K E E+ + ++ ++E +
Sbjct: 111 EKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQ 170
Query: 98 WEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEK 157
+K EE ++KE+ K N K K E + +E RE+K + ++ K
Sbjct: 171 VGEKEEERKEKERKER-----------KKRERNRKERKKERERKERRERKKERKKKEERK 219
Query: 158 QIKHFGMLRRWDDSQK 173
+ + W + ++
Sbjct: 220 KERQKDRQTNWREKER 235
Score = 40.8 bits (94), Expect = 0.002
Identities = 32/89 (35%), Positives = 49/89 (55%), Gaps = 9/89 (10%)
Query: 30 RWRHQARVERMEQF------QKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELER 83
R + R ER E+ +KE+E +R RE +++V E + + KE E E K E R
Sbjct: 135 RKEERKREERKERERKKEEREKERERKERKKRE-RKQVGEKEEERKEKERKERKKRERNR 193
Query: 84 LQAEAQQLRKE--ERSWEQKLEEMRKKEK 110
+ + ++ RKE ER E+K +E RKKE+
Sbjct: 194 KERKKERERKERRERKKERKKKEERKKER 222
Score = 38.1 bits (87), Expect = 0.013
Identities = 29/127 (22%), Positives = 61/127 (48%), Gaps = 9/127 (7%)
Query: 32 RHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQL 91
R + + ER + +KE+ E RE +++ E +RK + + + G+ + E + + ++
Sbjct: 48 RKEGKKERESERKKERRE-----REKRKREREKERKRERGKKEKKGERKKEERERKKRRR 102
Query: 92 RKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTF 151
KE + E+K E RKK++ SK+G + + + ++ E +E++ K
Sbjct: 103 EKENKEGEEK--EKRKKKEKK--ERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Query: 152 VEKYEKQ 158
K K+
Sbjct: 159 ERKERKK 165
Score = 37.4 bits (85), Expect = 0.022
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 9/92 (9%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAEL-------E 82
R + R + E+ +KE+E +R RE +++V E + + KE E E K E E
Sbjct: 141 REERKERERKKEEREKERERKERKKRE-RKQVGEKEEERKEKERKERKKRERNRKERKKE 199
Query: 83 RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPW 114
R + E ++ +KE + E++ +E R+K++ W
Sbjct: 200 RERKERRERKKERKKKEERKKE-RQKDRQTNW 230
Score = 33.1 bits (74), Expect = 0.42
Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 13/130 (10%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
W+ + R ER + + KE +K E +RK KE E K E E+ + + ++
Sbjct: 34 WQSEIR-EREREIETRKEG---------KKERESERK-KERREREKRKREREK-ERKRER 81
Query: 91 LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKT 150
+KE++ +K E RKK + N + K+ K + ++E E R+++ K
Sbjct: 82 GKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKR 141
Query: 151 FVEKYEKQIK 160
E+ E++ K
Sbjct: 142 -EERKERERK 150
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 47.0 bits (110), Expect = 3e-05
Identities = 62/276 (22%), Positives = 131/276 (47%), Gaps = 23/276 (8%)
Query: 40 MEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWE 99
+E ++++EEL++ E KRK+ E +++E + ++ KAELER+Q E + RKE +
Sbjct: 596 LEFERQQREELEK--LESKRKLIE---EMEEKQKSD--KAELERMQQEVETQRKETEIVQ 648
Query: 100 QKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEE----DSEEVREQKHKTFVEKY 155
++ + + K ++++ KD + + EK EE + +E+ QK + E +
Sbjct: 649 LQIRKQEESLKRRSFHIENKLKD------LLAEKEKFEEERLREQQEIELQKKRQEEETF 702
Query: 156 EKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIV 215
+ + L+ ++++K + ++ LE+E+K L EQ Q ++
Sbjct: 703 LRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKK-RLEEQEKEQVML 761
Query: 216 MQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAK--LRIEK 273
+ + E + K + R+ + +++ +EG + L KE G + +EK
Sbjct: 762 VAHLEEQLRE-KQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEK 820
Query: 274 AMKEYEEEERKKRLGPGGL--DPVEVYESLPEELQK 307
A + E +R++ + L D V+ + L +E+Q+
Sbjct: 821 AQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQE 856
Score = 32.3 bits (72), Expect = 0.72
Identities = 60/282 (21%), Positives = 124/282 (43%), Gaps = 46/282 (16%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGK-----AELERLQ------- 85
ER+ + Q+ + + R E +V E ++LKEL E + EL++LQ
Sbjct: 682 ERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQY 741
Query: 86 --AEAQQLRKEERSWEQKL------EEMRKKEK--------SMPW-NVDTLSKDGFSKSM 128
E ++ R EE+ EQ + E++R+K++ + W + +G +S+
Sbjct: 742 AKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESL 801
Query: 129 VNTKPEKT--EEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEET 186
+ K + +ED EE+ + + + F K + +K + + + L V E
Sbjct: 802 LRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQE-- 859
Query: 187 ANYLVIWCIDLEVEEKCALMEQVAHQ-TIVMQFILELAKSLKVDPRACFRQFFTKIKTAD 245
++ C+ E +++ L+E+ T V + + K V+ R +++ +++
Sbjct: 860 ----ILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKE--RQLQYLL 913
Query: 246 RQYMEGFNDELE-AFKERVRGRAKL-----RIEKAMKEYEEE 281
+ ++ +E + AF+ RG L ++EK M+E EE+
Sbjct: 914 QNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQ 955
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 46.6 bits (109), Expect = 4e-05
Identities = 91/398 (22%), Positives = 169/398 (42%), Gaps = 80/398 (20%)
Query: 16 EDETHPNIDTASL-FRWRHQARVERME-----QFQKEKEELDRGCRECK----RKVAECQ 65
ED+ N + ++ R QA +E+ + + QKEKEE +R RE + +K E +
Sbjct: 364 EDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELE 423
Query: 66 RKLK-----ELEVAEGGKAELERLQAEAQQLRKEER-SWE----QKLEEMRKKEKSMPWN 115
++L+ E + E + ++ER +A Q+L ++ R WE Q+L + +E+
Sbjct: 424 KRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVR 483
Query: 116 VDTLSKD-GFSKSMVNTKPEKTEEDSEEVR--EQKHKTFVEKYEKQ--IKHFGMLRRWDD 170
+++ K+ +N K ++ ++VR +Q KT +E +KQ ++ + + +
Sbjct: 484 LNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQE 543
Query: 171 SQKYLSDNVHLVCEE----------------TANYLVIWCIDLEVEEKC--------ALM 206
Q+Y + ++LV E+ + ++ LE EE C AL
Sbjct: 544 LQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALE 603
Query: 207 EQVAHQTIVMQFILELAKSLKV---DPRACFRQFF----TKIKTADRQYMEGFND---EL 256
++ A + M K L+ + Q + K+K +R+ +E E
Sbjct: 604 KETASKLSEMDSFNNQLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLED 663
Query: 257 EAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDV--KDV 314
EA ++ +G+ L E K EEEE++KR L + E + EE +K + KD
Sbjct: 664 EAARKAKQGKENLWKENLRK--EEEEKQKR-----LQEEKTQEKIQEEERKAEEKQRKDK 716
Query: 315 QMLQDAISKMD------------PTDAKYHMQRCIDSG 340
L+ K + P +A+ H + +SG
Sbjct: 717 DTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSG 754
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 45.8 bits (107), Expect = 6e-05
Identities = 36/161 (22%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAEL-----ERL 84
R + + R E+M + +K+ E D RE + ++ + K++ELE + E E++
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
Query: 85 QAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKD----GFSKSMVNTKPEKTEEDS 140
Q E ++++++E +++ E+++++E+ W + L K + + + EK E
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEK-TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Query: 141 EEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181
E+++EQ+ K +++ E++++ +R W +K V L
Sbjct: 517 EKMQEQEEK--MQRQEEKMRE-QEVRLWQQEEKMQEQEVRL 554
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
WR + ++ EQ +K +E+ D+ R+ + K+ E + K++E E + E R Q E Q
Sbjct: 328 WRQEEKMH--EQEEKIREQEDKMWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 91 LRKEERSW--EQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKH 148
+EE W E+K+ E +K + W + ++ + EK E EE+ Q+
Sbjct: 385 -EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE---------QDEKIREQEEEMWRQEE 434
Query: 149 K 149
K
Sbjct: 435 K 435
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 45.8 bits (107), Expect = 6e-05
Identities = 36/161 (22%), Positives = 83/161 (51%), Gaps = 13/161 (8%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAEL-----ERL 84
R + + R E+M + +K+ E D RE + ++ + K++ELE + E E++
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKM 457
Query: 85 QAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKD----GFSKSMVNTKPEKTEEDS 140
Q E ++++++E +++ E+++++E+ W + L K + + + EK E
Sbjct: 458 QEEEEKMQEQEEKIQRQEEKIQEQEEK-TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE 516
Query: 141 EEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181
E+++EQ+ K +++ E++++ +R W +K V L
Sbjct: 517 EKMQEQEEK--MQRQEEKMRE-QEVRLWQQEEKMQEQEVRL 554
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/121 (27%), Positives = 58/121 (47%), Gaps = 15/121 (12%)
Query: 31 WRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ 90
WR + ++ EQ +K +E+ D+ R+ + K+ E + K++E E + E R Q E Q
Sbjct: 328 WRQEEKMH--EQEEKIREQEDKMWRQ-EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 91 LRKEERSW--EQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKH 148
+EE W E+K+ E +K + W + ++ + EK E EE+ Q+
Sbjct: 385 -EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE---------QDEKIREQEEEMWRQEE 434
Query: 149 K 149
K
Sbjct: 435 K 435
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 45.8 bits (107), Expect = 6e-05
Identities = 33/146 (22%), Positives = 68/146 (46%), Gaps = 4/146 (2%)
Query: 9 HIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKL 68
H E ++ED+ + A L ER++ Q +K +R E + K A +R+
Sbjct: 253 HHEKMEEEDKERAEAERARL----EAEERERIKAEQDKKIADERARIEAEEKAAAQERER 308
Query: 69 KELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSM 128
+E E E + E +R E Q++++EE+ ++ + ++++EK + ++ +
Sbjct: 309 REAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 368
Query: 129 VNTKPEKTEEDSEEVREQKHKTFVEK 154
+ EE+ +V EQK +E+
Sbjct: 369 ERQRARAEEEEKAKVEEQKRNKQLEE 394
Score = 36.6 bits (83), Expect = 0.038
Identities = 32/133 (24%), Positives = 55/133 (41%), Gaps = 9/133 (6%)
Query: 32 RHQARVERMEQFQKEKEELDRGCRE--CKRKVAECQRKLKELEVAEGGKAELERLQAEAQ 89
+ Q +E+ +K++EE + E +RK E RKL+E E K E+ER +AEA
Sbjct: 557 KQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAA 616
Query: 90 QLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHK 149
+ R QK+ E + P+ T K+ + S V+
Sbjct: 617 EKR-------QKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQA 669
Query: 150 TFVEKYEKQIKHF 162
V K + +++ +
Sbjct: 670 AIVSKIDSRLEQY 682
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 45.8 bits (107), Expect = 6e-05
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 24 DTASLFRWRHQARVERMEQ--FQKEKEELDRGCR---ECKRKVAECQRKLKELEVAEGGK 78
+ A RW Q ER Q QK+KEE R E KR + +++ +E E E +
Sbjct: 643 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 702
Query: 79 AELERLQAE--------AQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVN 130
E ER + E A+Q R+ E+ Q E++++EK++ + L ++ K
Sbjct: 703 REQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 762
Query: 131 TKPEKTEEDSEEVREQKHK 149
+ E +E +E+K K
Sbjct: 763 EQQRLAERQLQEEQEKKAK 781
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 12/101 (11%)
Query: 16 EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAE 75
E+E A R Q ER EQ ++E+E ++ RE +R+ E +R+L E E
Sbjct: 669 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR--EQERQLAEQE--- 723
Query: 76 GGKAELERLQAEAQ------QLRKEERSWEQKLEEMRKKEK 110
+ E ERLQAE + LR ++ +++LEE +KKE+
Sbjct: 724 -RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 763
Score = 36.6 bits (83), Expect = 0.038
Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 9/132 (6%)
Query: 36 RVERMEQFQKEKEELDR----GCRECKRKVAECQRKLKELEVAEGGKA-ELERLQAEAQQ 90
++E +E +K++EE R E +R+ E +K KE E KA E +RL + +Q
Sbjct: 631 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 690
Query: 91 LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEV----REQ 146
R+E+ EQ+ E ++E+ L++ + + E+ ++ E+ +EQ
Sbjct: 691 ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQ 750
Query: 147 KHKTFVEKYEKQ 158
+ EK +K+
Sbjct: 751 LQRELEEKKKKE 762
Score = 35.8 bits (81), Expect = 0.065
Identities = 32/149 (21%), Positives = 73/149 (48%), Gaps = 22/149 (14%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQ 89
R + R E EQ +++K E D+ +R+L+E+++ K E ERL+ Q
Sbjct: 541 RLENLRRKEEAEQLRRQKVEEDK------------RRRLEEVKL----KRE-ERLRKVLQ 583
Query: 90 QLRKEERSWEQKLEEMRKK-----EKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVR 144
+ E+ E+K +++ +K EK+ + L+++ K K E+ E ++
Sbjct: 584 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 643
Query: 145 EQKHKTFVEKYEKQIKHFGMLRRWDDSQK 173
E + ++++ E++ +H +L++ + ++
Sbjct: 644 EARRLRWLQQEEEERRHQELLQKKKEEEQ 672
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 45.8 bits (107), Expect = 6e-05
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 24 DTASLFRWRHQARVERMEQ--FQKEKEELDRGCR---ECKRKVAECQRKLKELEVAEGGK 78
+ A RW Q ER Q QK+KEE R E KR + +++ +E E E +
Sbjct: 639 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER 698
Query: 79 AELERLQAE--------AQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVN 130
E ER + E A+Q R+ E+ Q E++++EK++ + L ++ K
Sbjct: 699 REQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
Query: 131 TKPEKTEEDSEEVREQKHK 149
+ E +E +E+K K
Sbjct: 759 EQQRLAERQLQEEQEKKAK 777
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/101 (33%), Positives = 53/101 (52%), Gaps = 12/101 (11%)
Query: 16 EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAE 75
E+E A R Q ER EQ ++E+E ++ RE +R+ E +R+L E E
Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR--EQERQLAEQE--- 719
Query: 76 GGKAELERLQAEAQ------QLRKEERSWEQKLEEMRKKEK 110
+ E ERLQAE + LR ++ +++LEE +KKE+
Sbjct: 720 -RRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759
Score = 36.6 bits (83), Expect = 0.038
Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 9/132 (6%)
Query: 36 RVERMEQFQKEKEELDR----GCRECKRKVAECQRKLKELEVAEGGKA-ELERLQAEAQQ 90
++E +E +K++EE R E +R+ E +K KE E KA E +RL + +Q
Sbjct: 627 KMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQ 686
Query: 91 LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEV----REQ 146
R+E+ EQ+ E ++E+ L++ + + E+ ++ E+ +EQ
Sbjct: 687 ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQ 746
Query: 147 KHKTFVEKYEKQ 158
+ EK +K+
Sbjct: 747 LQRELEEKKKKE 758
Score = 35.8 bits (81), Expect = 0.065
Identities = 32/149 (21%), Positives = 73/149 (48%), Gaps = 22/149 (14%)
Query: 30 RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQ 89
R + R E EQ +++K E D+ +R+L+E+++ K E ERL+ Q
Sbjct: 537 RLENLRRKEEAEQLRRQKVEEDK------------RRRLEEVKL----KRE-ERLRKVLQ 579
Query: 90 QLRKEERSWEQKLEEMRKK-----EKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVR 144
+ E+ E+K +++ +K EK+ + L+++ K K E+ E ++
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 145 EQKHKTFVEKYEKQIKHFGMLRRWDDSQK 173
E + ++++ E++ +H +L++ + ++
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQ 668
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/80 (42%), Positives = 49/80 (61%), Gaps = 8/80 (10%)
Query: 36 RVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEE 95
R ER E+ +K KEE R E K+K E +++LKE E E + + E+ +AE Q+L++E
Sbjct: 351 RAEREEK-EKLKEEAKRAKEEAKKKKEE-EKELKEKERREKREKD-EKEKAEKQRLKEER 407
Query: 96 R-----SWEQKLEEMRKKEK 110
R + E KLEE RKKE+
Sbjct: 408 RKERQEALEAKLEEKRKKEE 427
Score = 37.4 bits (85), Expect = 0.022
Identities = 28/125 (22%), Positives = 57/125 (45%), Gaps = 19/125 (15%)
Query: 32 RHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQL 91
R Q R+ + + + E+EE ++ E KR E ++K +E E+ E ++
Sbjct: 339 RDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE-----------EKELKEKERR 387
Query: 92 RKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTF 151
K E+ ++K E+ R KE+ + L + ++ +E+ + +RE++ +
Sbjct: 388 EKREKDEKEKAEKQRLKEERRKERQEALE--------AKLEEKRKKEEEKRLREEEKRIK 439
Query: 152 VEKYE 156
EK E
Sbjct: 440 AEKAE 444
Score = 34.7 bits (78), Expect = 0.15
Identities = 24/106 (22%), Positives = 52/106 (49%), Gaps = 3/106 (2%)
Query: 58 KRKVAECQRKLKELEVAEGGKAELERLQAEAQQLR---KEERSWEQKLEEMRKKEKSMPW 114
K ++ Q +L + + E E+L+ EA++ + K+++ E++L+E ++EK
Sbjct: 334 KLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKD 393
Query: 115 NVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIK 160
+ K + + E E EE R+++ + + + EK+IK
Sbjct: 394 EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 44.7 bits (104), Expect = 1e-04
Identities = 51/261 (19%), Positives = 119/261 (45%), Gaps = 23/261 (8%)
Query: 38 ERMEQFQKEKEELDRG---CRECKRKVAECQRKLK-ELEVAEGGKAELERLQAEAQQLRK 93
E +++++ E +L+ R+ +++ +R L+ ELE A+G ++ + Q + + K
Sbjct: 864 ETLKKYEGEIRQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLK 923
Query: 94 EERSWEQKLEEMRKKEKSMPWN----VDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHK 149
EE +++L ++ + ++ W+ ++ L K+ +V T E ++ E K K
Sbjct: 924 EESEQKEQLRRLKNEMENERWHLGKTIEKLQKE--MADIVEASRTSTLELQNQLDEYKEK 981
Query: 150 TFVE--KYEKQIKHFGM-LRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALM 206
E + ++Q+K + + + + D + L+ EE +Y +++
Sbjct: 982 NRRELAEMQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDY-------QRAQDEALTK 1034
Query: 207 EQVAHQTIV-MQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRG 265
Q+ QT+ +++ LE LK D +Q K+ + + E N+ + ER+
Sbjct: 1035 RQLLEQTLKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNS-DLLSERI-S 1092
Query: 266 RAKLRIEKAMKEYEEEERKKR 286
R++ ++E+ E +E ++
Sbjct: 1093 RSREQMEQLRNELLQERAARQ 1113
Score = 30.8 bits (68), Expect = 2.1
Identities = 19/116 (16%), Positives = 53/116 (45%), Gaps = 12/116 (10%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVA------------EGGKAELERLQ 85
+R+E ++++ L R +RKV E ++ + ++ + K ++E +
Sbjct: 1160 DRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAE 1219
Query: 86 AEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSE 141
E +L ++ +++LEE + + ++++ KD K + + + ++D +
Sbjct: 1220 EEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLDDMDDDDD 1275
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 44.7 bits (104), Expect = 1e-04
Identities = 36/114 (31%), Positives = 57/114 (50%), Gaps = 13/114 (11%)
Query: 34 QARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRK 93
Q RVE+ EQ + E+EEL R E + ++ E RK +E E + E E+ + E ++ RK
Sbjct: 420 QERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEE----ERKRQEEEKKKQEGEEKRK 475
Query: 94 EERSWEQKL-EEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQ 146
++K EE+ KEK ++ K+M+ + E E + EV EQ
Sbjct: 476 AGEEAKRKAEEELLLKEKQ--------EQEKQEKAMIEKQKEAAETKAREVAEQ 521
Score = 37.4 bits (85), Expect = 0.022
Identities = 40/138 (28%), Positives = 65/138 (47%), Gaps = 21/138 (15%)
Query: 32 RHQARV--ERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQ 89
R QAR+ E+ EQ + EKEE DR RE +LK KAE ERL+ E +
Sbjct: 408 RRQARLQKEQEEQERVEKEEQDRLERE----------ELKR-------KAEEERLRLE-E 449
Query: 90 QLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHK 149
+ RK+E +++ EE +K+E +K + ++ K ++ +E E+ +K K
Sbjct: 450 EARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELL-LKEKQEQEKQEKAMIEKQK 508
Query: 150 TFVEKYEKQIKHFGMLRR 167
E +++ L R
Sbjct: 509 EAAETKAREVAEQMRLER 526
Score = 36.2 bits (82), Expect = 0.050
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 16 EDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAE 75
E E ++ L R + R+ E+ +K++EE R E K++ E +RK E
Sbjct: 424 EKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGE---EA 480
Query: 76 GGKAELERLQAEAQQLRKEERSWEQKLEE 104
KAE E L E Q+ K+E++ +K +E
Sbjct: 481 KRKAEEELLLKEKQEQEKQEKAMIEKQKE 509
>gi|16905073 SoxLZ/Sox6 leucine zipper binding protein [Homo
sapiens]
Length = 269
Score = 44.3 bits (103), Expect = 2e-04
Identities = 40/150 (26%), Positives = 68/150 (45%), Gaps = 30/150 (20%)
Query: 47 KEELDRGCRECKRKVAECQRKLKEL--EVAEGGKAELERLQAEAQQLRKEERSWEQKLEE 104
+EEL R C E + + ECQ KL + E A+L L + + L E W++K E
Sbjct: 21 EEELIRECEEMWKDMEECQNKLSLIGTETLTDSNAQLSLLIMQVKCLTAELSQWQKKTPE 80
Query: 105 MRKKEKSMPWNVD---TLSKDGFSKSMVNTKPEKTEEDSEEV---REQKHKTFVEKYEKQ 158
++P D TL K+ F +K +D E V +E K++ E E++
Sbjct: 81 ------TIPLTEDVLITLGKEEF---------QKLRQDLEMVLSTKESKNEKLKEDLERE 125
Query: 159 IKHFGMLRRWDDSQKYLSDNVHLVCEETAN 188
+RW D Q+ + ++++++ E N
Sbjct: 126 -------QRWLDEQQQIMESLNVLHSELKN 148
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 43.9 bits (102), Expect = 2e-04
Identities = 55/262 (20%), Positives = 110/262 (41%), Gaps = 17/262 (6%)
Query: 39 RMEQFQKEKEELDRGCRECKRK-VAECQRKLKELEVAEGGKA-------ELERLQAE--- 87
R E ++EKE + + + K+K V E ++K+ E+ G KA +LE L +
Sbjct: 613 RQEAKEREKERILQEHEQIKKKTVRERLEQIKKTEL--GAKAFKDIDIEDLEELDPDFIM 670
Query: 88 ---AQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVR 144
+QL KE++ +++L+ KK L + KS + K + E+
Sbjct: 671 AKQVEQLEKEKKELQERLKNQEKKIDYFE-RAKRLEEIPLIKSAYEEQRIKDMDLWEQQE 729
Query: 145 EQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCA 204
E++ T + EK ++H + R + + + + + + EE+
Sbjct: 730 EERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHN 789
Query: 205 LMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVR 264
+E+ Q + I + + + R Q + + +R +EL ++ERV+
Sbjct: 790 RLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVK 849
Query: 265 GRAKLRIEKAMKEYEEEERKKR 286
++ +K +E E EER++R
Sbjct: 850 KLEEVERKKRQRELEIEERERR 871
Score = 35.4 bits (80), Expect = 0.085
Identities = 65/306 (21%), Positives = 125/306 (40%), Gaps = 78/306 (25%)
Query: 12 VSDDEDETHPNIDTASL--FRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLK 69
+ +++E H TA L R HQ + R + ++ KE L+ QR+
Sbjct: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLES---------LNIQRE-- 590
Query: 70 ELEVAEGGKAELERLQAEAQQLRK-EERSWEQKLEEMRK----------KEKSMPWNVDT 118
K ELE+ +AE Q++RK EE Q+ +E K K+K++ ++
Sbjct: 591 --------KEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQ 642
Query: 119 LSKDGFSKS-----------------MVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKH 161
+ K ++ + E+ E++ +E++E+ ++ EK+I +
Sbjct: 643 IKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQER-----LKNQEKKIDY 697
Query: 162 FGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILE 221
F +R ++ S E+ + +W + + EE+ M+ LE
Sbjct: 698 FERAKRLEEIPLIKS----AYEEQRIKDMDLW--EQQEEERITTMQ------------LE 739
Query: 222 LAKSLKVDPRAC----FRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKE 277
K+L+ R R F A RQ + + ++L+ F+ER+ R+E+ ++
Sbjct: 740 REKALEHKNRMSRMLEDRDLFVMRLKAARQSV--YEEKLKQFEERLAEERHNRLEERKRQ 797
Query: 278 YEEEER 283
+EE R
Sbjct: 798 RKEERR 803
Score = 34.3 bits (77), Expect = 0.19
Identities = 29/136 (21%), Positives = 63/136 (46%), Gaps = 11/136 (8%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKV--AECQRKLKELEVAEGGKAELERLQAEAQQLRKEE 95
+++EQ +KEK+EL + ++K+ E ++L+E+ + + E + + ++EE
Sbjct: 672 KQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEE 731
Query: 96 RSWEQKLEEMRKKEKSMPWNVDTLSKDGF----SKSMVNTKPEKTEEDSEEVREQKHKTF 151
R +LE + E + +D F + + EK ++ E + E++H
Sbjct: 732 RITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRL 791
Query: 152 VE-----KYEKQIKHF 162
E K E++I ++
Sbjct: 792 EERKRQRKEERRITYY 807
Score = 30.0 bits (66), Expect = 3.6
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 32 RHQARVERMEQFQKE-KEELDRGCRECKRKVAECQR--KLKELEVAEGGKAELERLQAEA 88
R E+++QF++ EE E KR+ E +R +E E E +AE + L+
Sbjct: 768 RQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE 827
Query: 89 QQLRKEERSWEQKLEEMRKKEKSM 112
++ R E E++L E +++ K +
Sbjct: 828 ERERAERAKREEELREYQERVKKL 851
>gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
sapiens]
Length = 731
Score = 43.9 bits (102), Expect = 2e-04
Identities = 85/365 (23%), Positives = 143/365 (39%), Gaps = 88/365 (24%)
Query: 37 VERMEQFQKEKEELDRGCREC--KRKVAECQRKLKEL--EVAEGGKAE--------LERL 84
+ ++++ +EK EL EC KRK+A +++ L E+ + K+E ER
Sbjct: 205 ISQLQEAHEEKNEL-----ECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERF 259
Query: 85 QAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVR 144
QA +Q+L ++ EQ+LE++ +K+K + L D NTK + T ++E+
Sbjct: 260 QARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENTKLKLT---NQELA 316
Query: 145 EQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCE--ETANYLVIWCIDLEVEEK 202
+ +T +E Q D+Q+ L C+ + V + EK
Sbjct: 317 RELERT---SWELQ-----------DAQQQLESLQQEACKLHQEKEMEVYRVTESLQREK 362
Query: 203 CALMEQVAHQTIVMQFILELAKSLKVDPRACF-RQFFTKIKTADR-------------QY 248
L++Q + F+ E K L+ + CF + K TA +Y
Sbjct: 363 AGLLKQ-------LDFLRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKY 415
Query: 249 ME--GFNDELEAFKERVRGRAKLRIEKAMKEY---EEEERKKRLGPGGLDPVEVYESLPE 303
++ G +E V G + R + Y EEE GPGG P
Sbjct: 416 VDSRGILRSQSEEEEEVFGIPR-RSSLGLSGYPLTEEEPGTGEPGPGG--------PYPR 466
Query: 304 ELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKEGEEAGPGDPL 363
L++ V++ DP + + +D G P SK SE +E + G +
Sbjct: 467 PLRRIISVEE-----------DP------LPQLLDGGFEQPLSKCSEEEEVSDQGVQGQI 509
Query: 364 LEAVP 368
EA P
Sbjct: 510 PEAPP 514
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 43.5 bits (101), Expect = 3e-04
Identities = 61/278 (21%), Positives = 125/278 (44%), Gaps = 34/278 (12%)
Query: 31 WRHQARVERMEQFQKEKEEL---DRGCRECKRKVAECQRKLKELE------------VAE 75
WR +V+ + Q +++EE+ + ++ K + + + +LKELE + E
Sbjct: 835 WRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
Query: 76 GGKAELERLQAEAQQLRKEERSWEQKLEEM------RKKEKSMPWNVDTLSKDGFSKSMV 129
+AE E L AEA+++R + +Q+LEE+ R +E+ + ++ M+
Sbjct: 895 QLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 130 NTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANY 189
+ + + EE++ + Q K E K+++ ++ DD LS L+ EE +
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV--MDDQNNKLSKERKLL-EERISD 1010
Query: 190 LVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYM 249
L + E + K + H++++ + + L K K RQ K+K
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK------SRQELEKLKRKLEGDA 1064
Query: 250 EGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRL 287
F++++ + ++ A+L+++ A KE E + RL
Sbjct: 1065 SDFHEQIADLQAQI---AELKMQLAKKEEELQAALARL 1099
Score = 37.4 bits (85), Expect = 0.022
Identities = 81/362 (22%), Positives = 149/362 (41%), Gaps = 62/362 (17%)
Query: 16 EDETHPNIDTASLFRWRHQARVE----RMEQFQKEKEELDRGCRECKRKVAECQRKLKEL 71
++ET + R +H VE ++EQF++ K LD+ + +++ A+ +L+ L
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 72 EVAEGGKAELE----RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDT--------- 118
A K E+E +L+A+ Q+L+ + E+ E+ K + V++
Sbjct: 1244 GQA---KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
Query: 119 -----LSKDGFS------------------KSMVNTKPEKTEEDSEEVREQKHKTFVEKY 155
L+KD S K V+TK + EE+ +++Q + K
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Query: 156 EKQIKHFGMLR-RWDDSQKYLSDNVHLV--CEETANYL--VIWCIDLEVEEKCALMEQVA 210
+ +H L + DS+K L D V EE I + + EEK A +++
Sbjct: 1361 NLE-RHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1419
Query: 211 HQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLR 270
+Q L+ L VD RQ + ++ R++ D+L A ++ + +
Sbjct: 1420 KTKNRLQQELD---DLVVD-LDNQRQLVSNLEKKQRKF-----DQLLAEEKNISSKYADE 1470
Query: 271 IEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAK 330
++A E E+E K L+ E E+ EEL++ + +M +D +S D
Sbjct: 1471 RDRAEAEAREKETKALSLARALE--EALEA-KEELERTNKMLKAEM-EDLVSSKDDVGKN 1526
Query: 331 YH 332
H
Sbjct: 1527 VH 1528
Score = 33.9 bits (76), Expect = 0.25
Identities = 25/97 (25%), Positives = 49/97 (50%), Gaps = 15/97 (15%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAEC------QRKLKEL--EVAEGGKA-------ELE 82
E++EQ +EK+ + ++ +K+ E +RK+ E E AE G A +LE
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1887
Query: 83 RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTL 119
+ E+Q++ R +++L+E + ++M V+ L
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Score = 32.3 bits (72), Expect = 0.72
Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 32/157 (20%)
Query: 34 QARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELER----LQAEAQ 89
Q E K +E DR E + K + + LE A K ELER L+AE +
Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514
Query: 90 --------------QLRKEERSWEQKLEEMR------------KKEKSMPWNVDTLSKDG 123
+L K +R+ E ++EEM+ ++ + V+ + G
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1574
Query: 124 FSKSMVNTKPEKTEEDSEEVREQKH--KTFVEKYEKQ 158
+ + + E+ EE +++ Q H +T +E KQ
Sbjct: 1575 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611
Score = 29.6 bits (65), Expect = 4.7
Identities = 57/288 (19%), Positives = 120/288 (41%), Gaps = 55/288 (19%)
Query: 9 HIEVSDDEDETHPNIDTASLF---RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQ 65
+I++SD + + T + R Q +E + Q +EK + K ++ Q
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL---Q 1426
Query: 66 RKLKELEVAEGGKAEL----ERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSK 121
++L +L V + +L E+ Q + QL EE++ K + R + ++ + K
Sbjct: 1427 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA-----EAREK 1481
Query: 122 DGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181
+ + S+ E E ++E E+ +K + E + S+ + NVH
Sbjct: 1482 ETKALSLARALEEALE--AKEELERTNKMLKAEMEDLV----------SSKDDVGKNVHE 1529
Query: 182 VCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKI 241
+ + ++ ++EE +E++ + +Q + L+V+ +A QF +
Sbjct: 1530 LEKSKR------ALETQMEEMKTQLEELEDE---LQATEDAKLRLEVNMQALKGQFERDL 1580
Query: 242 KTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYE---EEERKKR 286
+ D Q N+E + ++++ + EYE E+ERK+R
Sbjct: 1581 QARDEQ-----NEE-----------KRRQLQRQLHEYETELEDERKQR 1612
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 43.5 bits (101), Expect = 3e-04
Identities = 61/278 (21%), Positives = 125/278 (44%), Gaps = 34/278 (12%)
Query: 31 WRHQARVERMEQFQKEKEEL---DRGCRECKRKVAECQRKLKELE------------VAE 75
WR +V+ + Q +++EE+ + ++ K + + + +LKELE + E
Sbjct: 842 WRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 901
Query: 76 GGKAELERLQAEAQQLRKEERSWEQKLEEM------RKKEKSMPWNVDTLSKDGFSKSMV 129
+AE E L AEA+++R + +Q+LEE+ R +E+ + ++ M+
Sbjct: 902 QLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960
Query: 130 NTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANY 189
+ + + EE++ + Q K E K+++ ++ DD LS L+ EE +
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV--MDDQNNKLSKERKLL-EERISD 1017
Query: 190 LVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYM 249
L + E + K + H++++ + + L K K RQ K+K
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK------SRQELEKLKRKLEGDA 1071
Query: 250 EGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRL 287
F++++ + ++ A+L+++ A KE E + RL
Sbjct: 1072 SDFHEQIADLQAQI---AELKMQLAKKEEELQAALARL 1106
Score = 37.4 bits (85), Expect = 0.022
Identities = 81/362 (22%), Positives = 149/362 (41%), Gaps = 62/362 (17%)
Query: 16 EDETHPNIDTASLFRWRHQARVE----RMEQFQKEKEELDRGCRECKRKVAECQRKLKEL 71
++ET + R +H VE ++EQF++ K LD+ + +++ A+ +L+ L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250
Query: 72 EVAEGGKAELE----RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDT--------- 118
A K E+E +L+A+ Q+L+ + E+ E+ K + V++
Sbjct: 1251 GQA---KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1307
Query: 119 -----LSKDGFS------------------KSMVNTKPEKTEEDSEEVREQKHKTFVEKY 155
L+KD S K V+TK + EE+ +++Q + K
Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367
Query: 156 EKQIKHFGMLR-RWDDSQKYLSDNVHLV--CEETANYL--VIWCIDLEVEEKCALMEQVA 210
+ +H L + DS+K L D V EE I + + EEK A +++
Sbjct: 1368 NLE-RHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1426
Query: 211 HQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLR 270
+Q L+ L VD RQ + ++ R++ D+L A ++ + +
Sbjct: 1427 KTKNRLQQELD---DLVVD-LDNQRQLVSNLEKKQRKF-----DQLLAEEKNISSKYADE 1477
Query: 271 IEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAK 330
++A E E+E K L+ E E+ EEL++ + +M +D +S D
Sbjct: 1478 RDRAEAEAREKETKALSLARALE--EALEA-KEELERTNKMLKAEM-EDLVSSKDDVGKN 1533
Query: 331 YH 332
H
Sbjct: 1534 VH 1535
Score = 33.9 bits (76), Expect = 0.25
Identities = 25/97 (25%), Positives = 49/97 (50%), Gaps = 15/97 (15%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAEC------QRKLKEL--EVAEGGKA-------ELE 82
E++EQ +EK+ + ++ +K+ E +RK+ E E AE G A +LE
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1894
Query: 83 RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTL 119
+ E+Q++ R +++L+E + ++M V+ L
Sbjct: 1895 EAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1931
Score = 32.3 bits (72), Expect = 0.72
Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 32/157 (20%)
Query: 34 QARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELER----LQAEAQ 89
Q E K +E DR E + K + + LE A K ELER L+AE +
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Query: 90 --------------QLRKEERSWEQKLEEMR------------KKEKSMPWNVDTLSKDG 123
+L K +R+ E ++EEM+ ++ + V+ + G
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1581
Query: 124 FSKSMVNTKPEKTEEDSEEVREQKH--KTFVEKYEKQ 158
+ + + E+ EE +++ Q H +T +E KQ
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618
Score = 29.6 bits (65), Expect = 4.7
Identities = 57/288 (19%), Positives = 120/288 (41%), Gaps = 55/288 (19%)
Query: 9 HIEVSDDEDETHPNIDTASLF---RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQ 65
+I++SD + + T + R Q +E + Q +EK + K ++ Q
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL---Q 1433
Query: 66 RKLKELEVAEGGKAEL----ERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSK 121
++L +L V + +L E+ Q + QL EE++ K + R + ++ + K
Sbjct: 1434 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA-----EAREK 1488
Query: 122 DGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181
+ + S+ E E ++E E+ +K + E + S+ + NVH
Sbjct: 1489 ETKALSLARALEEALE--AKEELERTNKMLKAEMEDLV----------SSKDDVGKNVHE 1536
Query: 182 VCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKI 241
+ + ++ ++EE +E++ + +Q + L+V+ +A QF +
Sbjct: 1537 LEKSKR------ALETQMEEMKTQLEELEDE---LQATEDAKLRLEVNMQALKGQFERDL 1587
Query: 242 KTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYE---EEERKKR 286
+ D Q N+E + ++++ + EYE E+ERK+R
Sbjct: 1588 QARDEQ-----NEE-----------KRRQLQRQLHEYETELEDERKQR 1619
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 43.5 bits (101), Expect = 3e-04
Identities = 61/278 (21%), Positives = 125/278 (44%), Gaps = 34/278 (12%)
Query: 31 WRHQARVERMEQFQKEKEEL---DRGCRECKRKVAECQRKLKELE------------VAE 75
WR +V+ + Q +++EE+ + ++ K + + + +LKELE + E
Sbjct: 842 WRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 901
Query: 76 GGKAELERLQAEAQQLRKEERSWEQKLEEM------RKKEKSMPWNVDTLSKDGFSKSMV 129
+AE E L AEA+++R + +Q+LEE+ R +E+ + ++ M+
Sbjct: 902 QLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 960
Query: 130 NTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANY 189
+ + + EE++ + Q K E K+++ ++ DD LS L+ EE +
Sbjct: 961 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV--MDDQNNKLSKERKLL-EERISD 1017
Query: 190 LVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYM 249
L + E + K + H++++ + + L K K RQ K+K
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK------SRQELEKLKRKLEGDA 1071
Query: 250 EGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRL 287
F++++ + ++ A+L+++ A KE E + RL
Sbjct: 1072 SDFHEQIADLQAQI---AELKMQLAKKEEELQAALARL 1106
Score = 37.4 bits (85), Expect = 0.022
Identities = 81/362 (22%), Positives = 149/362 (41%), Gaps = 62/362 (17%)
Query: 16 EDETHPNIDTASLFRWRHQARVE----RMEQFQKEKEELDRGCRECKRKVAECQRKLKEL 71
++ET + R +H VE ++EQF++ K LD+ + +++ A+ +L+ L
Sbjct: 1191 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1250
Query: 72 EVAEGGKAELE----RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDT--------- 118
A K E+E +L+A+ Q+L+ + E+ E+ K + V++
Sbjct: 1251 GQA---KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1307
Query: 119 -----LSKDGFS------------------KSMVNTKPEKTEEDSEEVREQKHKTFVEKY 155
L+KD S K V+TK + EE+ +++Q + K
Sbjct: 1308 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1367
Query: 156 EKQIKHFGMLR-RWDDSQKYLSDNVHLV--CEETANYL--VIWCIDLEVEEKCALMEQVA 210
+ +H L + DS+K L D V EE I + + EEK A +++
Sbjct: 1368 NLE-RHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1426
Query: 211 HQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLR 270
+Q L+ L VD RQ + ++ R++ D+L A ++ + +
Sbjct: 1427 KTKNRLQQELD---DLVVD-LDNQRQLVSNLEKKQRKF-----DQLLAEEKNISSKYADE 1477
Query: 271 IEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAK 330
++A E E+E K L+ E E+ EEL++ + +M +D +S D
Sbjct: 1478 RDRAEAEAREKETKALSLARALE--EALEA-KEELERTNKMLKAEM-EDLVSSKDDVGKN 1533
Query: 331 YH 332
H
Sbjct: 1534 VH 1535
Score = 33.9 bits (76), Expect = 0.25
Identities = 25/97 (25%), Positives = 49/97 (50%), Gaps = 15/97 (15%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAEC------QRKLKEL--EVAEGGKA-------ELE 82
E++EQ +EK+ + ++ +K+ E +RK+ E E AE G A +LE
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1894
Query: 83 RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTL 119
+ E+Q++ R +++L+E + ++M V+ L
Sbjct: 1895 EAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1931
Score = 32.3 bits (72), Expect = 0.72
Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 32/157 (20%)
Query: 34 QARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELER----LQAEAQ 89
Q E K +E DR E + K + + LE A K ELER L+AE +
Sbjct: 1462 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1521
Query: 90 --------------QLRKEERSWEQKLEEMR------------KKEKSMPWNVDTLSKDG 123
+L K +R+ E ++EEM+ ++ + V+ + G
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1581
Query: 124 FSKSMVNTKPEKTEEDSEEVREQKH--KTFVEKYEKQ 158
+ + + E+ EE +++ Q H +T +E KQ
Sbjct: 1582 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1618
Score = 29.6 bits (65), Expect = 4.7
Identities = 57/288 (19%), Positives = 120/288 (41%), Gaps = 55/288 (19%)
Query: 9 HIEVSDDEDETHPNIDTASLF---RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQ 65
+I++SD + + T + R Q +E + Q +EK + K ++ Q
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL---Q 1433
Query: 66 RKLKELEVAEGGKAEL----ERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSK 121
++L +L V + +L E+ Q + QL EE++ K + R + ++ + K
Sbjct: 1434 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA-----EAREK 1488
Query: 122 DGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181
+ + S+ E E ++E E+ +K + E + S+ + NVH
Sbjct: 1489 ETKALSLARALEEALE--AKEELERTNKMLKAEMEDLV----------SSKDDVGKNVHE 1536
Query: 182 VCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKI 241
+ + ++ ++EE +E++ + +Q + L+V+ +A QF +
Sbjct: 1537 LEKSKR------ALETQMEEMKTQLEELEDE---LQATEDAKLRLEVNMQALKGQFERDL 1587
Query: 242 KTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYE---EEERKKR 286
+ D Q N+E + ++++ + EYE E+ERK+R
Sbjct: 1588 QARDEQ-----NEE-----------KRRQLQRQLHEYETELEDERKQR 1619
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 43.5 bits (101), Expect = 3e-04
Identities = 61/278 (21%), Positives = 125/278 (44%), Gaps = 34/278 (12%)
Query: 31 WRHQARVERMEQFQKEKEEL---DRGCRECKRKVAECQRKLKELE------------VAE 75
WR +V+ + Q +++EE+ + ++ K + + + +LKELE + E
Sbjct: 835 WRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQE 894
Query: 76 GGKAELERLQAEAQQLRKEERSWEQKLEEM------RKKEKSMPWNVDTLSKDGFSKSMV 129
+AE E L AEA+++R + +Q+LEE+ R +E+ + ++ M+
Sbjct: 895 QLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQML 953
Query: 130 NTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANY 189
+ + + EE++ + Q K E K+++ ++ DD LS L+ EE +
Sbjct: 954 DLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILV--MDDQNNKLSKERKLL-EERISD 1010
Query: 190 LVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYM 249
L + E + K + H++++ + + L K K RQ K+K
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK------SRQELEKLKRKLEGDA 1064
Query: 250 EGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRL 287
F++++ + ++ A+L+++ A KE E + RL
Sbjct: 1065 SDFHEQIADLQAQI---AELKMQLAKKEEELQAALARL 1099
Score = 37.4 bits (85), Expect = 0.022
Identities = 81/362 (22%), Positives = 149/362 (41%), Gaps = 62/362 (17%)
Query: 16 EDETHPNIDTASLFRWRHQARVE----RMEQFQKEKEELDRGCRECKRKVAECQRKLKEL 71
++ET + R +H VE ++EQF++ K LD+ + +++ A+ +L+ L
Sbjct: 1184 DEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVL 1243
Query: 72 EVAEGGKAELE----RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDT--------- 118
A K E+E +L+A+ Q+L+ + E+ E+ K + V++
Sbjct: 1244 GQA---KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAE 1300
Query: 119 -----LSKDGFS------------------KSMVNTKPEKTEEDSEEVREQKHKTFVEKY 155
L+KD S K V+TK + EE+ +++Q + K
Sbjct: 1301 GKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQ 1360
Query: 156 EKQIKHFGMLR-RWDDSQKYLSDNVHLV--CEETANYL--VIWCIDLEVEEKCALMEQVA 210
+ +H L + DS+K L D V EE I + + EEK A +++
Sbjct: 1361 NLE-RHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1419
Query: 211 HQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLR 270
+Q L+ L VD RQ + ++ R++ D+L A ++ + +
Sbjct: 1420 KTKNRLQQELD---DLVVD-LDNQRQLVSNLEKKQRKF-----DQLLAEEKNISSKYADE 1470
Query: 271 IEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAK 330
++A E E+E K L+ E E+ EEL++ + +M +D +S D
Sbjct: 1471 RDRAEAEAREKETKALSLARALE--EALEA-KEELERTNKMLKAEM-EDLVSSKDDVGKN 1526
Query: 331 YH 332
H
Sbjct: 1527 VH 1528
Score = 33.9 bits (76), Expect = 0.25
Identities = 25/97 (25%), Positives = 49/97 (50%), Gaps = 15/97 (15%)
Query: 38 ERMEQFQKEKEELDRGCRECKRKVAEC------QRKLKEL--EVAEGGKA-------ELE 82
E++EQ +EK+ + ++ +K+ E +RK+ E E AE G A +LE
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLE 1887
Query: 83 RLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTL 119
+ E+Q++ R +++L+E + ++M V+ L
Sbjct: 1888 EAEEESQRINANRRKLQRELDEATESNEAMGREVNAL 1924
Score = 32.3 bits (72), Expect = 0.72
Identities = 37/157 (23%), Positives = 63/157 (40%), Gaps = 32/157 (20%)
Query: 34 QARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELER----LQAEAQ 89
Q E K +E DR E + K + + LE A K ELER L+AE +
Sbjct: 1455 QLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1514
Query: 90 --------------QLRKEERSWEQKLEEMR------------KKEKSMPWNVDTLSKDG 123
+L K +R+ E ++EEM+ ++ + V+ + G
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKG 1574
Query: 124 FSKSMVNTKPEKTEEDSEEVREQKH--KTFVEKYEKQ 158
+ + + E+ EE +++ Q H +T +E KQ
Sbjct: 1575 QFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQ 1611
Score = 29.6 bits (65), Expect = 4.7
Identities = 57/288 (19%), Positives = 120/288 (41%), Gaps = 55/288 (19%)
Query: 9 HIEVSDDEDETHPNIDTASLF---RWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQ 65
+I++SD + + T + R Q +E + Q +EK + K ++ Q
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRL---Q 1426
Query: 66 RKLKELEVAEGGKAEL----ERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSK 121
++L +L V + +L E+ Q + QL EE++ K + R + ++ + K
Sbjct: 1427 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA-----EAREK 1481
Query: 122 DGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHL 181
+ + S+ E E ++E E+ +K + E + S+ + NVH
Sbjct: 1482 ETKALSLARALEEALE--AKEELERTNKMLKAEMEDLV----------SSKDDVGKNVHE 1529
Query: 182 VCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKI 241
+ + ++ ++EE +E++ + +Q + L+V+ +A QF +
Sbjct: 1530 LEKSKR------ALETQMEEMKTQLEELEDE---LQATEDAKLRLEVNMQALKGQFERDL 1580
Query: 242 KTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYE---EEERKKR 286
+ D Q N+E + ++++ + EYE E+ERK+R
Sbjct: 1581 QARDEQ-----NEE-----------KRRQLQRQLHEYETELEDERKQR 1612
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,314,048
Number of Sequences: 37866
Number of extensions: 716734
Number of successful extensions: 7241
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 177
Number of HSP's successfully gapped in prelim test: 688
Number of HSP's that attempted gapping in prelim test: 4424
Number of HSP's gapped (non-prelim): 2708
length of query: 378
length of database: 18,247,518
effective HSP length: 104
effective length of query: 274
effective length of database: 14,309,454
effective search space: 3920790396
effective search space used: 3920790396
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.