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Search of human proteins with 58761486
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58761486 chaperonin containing TCP1, subunit 3 isoform b
[Homo sapiens]
(544 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Hom... 1065 0.0
gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Hom... 1060 0.0
gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Hom... 966 0.0
gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo ... 300 2e-81
gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Hom... 294 1e-79
gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo... 284 1e-76
gi|57863257 T-complex protein 1 isoform a [Homo sapiens] 280 2e-75
gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Hom... 264 1e-70
gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens] 258 1e-68
gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens] 221 1e-57
gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo ... 212 6e-55
gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Ho... 204 2e-52
gi|57863259 T-complex protein 1 isoform b [Homo sapiens] 167 2e-41
gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Hom... 163 3e-40
gi|7657253 T-complex protein 1 [Homo sapiens] 154 2e-37
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 99 1e-20
gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens] 76 9e-14
gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens] 76 9e-14
gi|41399285 chaperonin [Homo sapiens] 56 1e-07
gi|31542947 chaperonin [Homo sapiens] 56 1e-07
gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens] 48 2e-05
gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens] 35 0.23
gi|14251207 MOV10-like 1 [Homo sapiens] 32 1.9
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 32 1.9
gi|10190716 spindle pole body component 25 [Homo sapiens] 32 1.9
gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens] 31 2.5
gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens] 31 2.5
gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens] 31 2.5
gi|11968182 ribosomal protein S18 [Homo sapiens] 31 2.5
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 30 4.3
>gi|58761486 chaperonin containing TCP1, subunit 3 isoform b [Homo
sapiens]
Length = 544
Score = 1065 bits (2753), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT
Sbjct: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
Query: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILGEMLSVAEHFLEQQMHPTV 120
NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILGEMLSVAEHFLEQQMHPTV
Sbjct: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILGEMLSVAEHFLEQQMHPTV 120
Query: 121 VISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVK 180
VISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVK
Sbjct: 121 VISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVK 180
Query: 181 MVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLL 240
MVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLL
Sbjct: 181 MVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLL 240
Query: 241 DSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQ 300
DSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQ
Sbjct: 241 DSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQ 300
Query: 301 HYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFT 360
HYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFT
Sbjct: 301 HYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFT 360
Query: 361 FITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHA 420
FITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHA
Sbjct: 361 FITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHA 420
Query: 421 LTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVN 480
LTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVN
Sbjct: 421 LTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVN 480
Query: 481 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 540
GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD
Sbjct: 481 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 540
Query: 541 AGQE 544
AGQE
Sbjct: 541 AGQE 544
>gi|63162572 chaperonin containing TCP1, subunit 3 isoform a [Homo
sapiens]
Length = 545
Score = 1060 bits (2741), Expect = 0.0
Identities = 544/545 (99%), Positives = 544/545 (99%), Gaps = 1/545 (0%)
Query: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT
Sbjct: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
Query: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPT 119
NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL GEMLSVAEHFLEQQMHPT
Sbjct: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 120
Query: 120 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 179
VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
Sbjct: 121 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 180
Query: 180 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 239
KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
Sbjct: 181 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 240
Query: 240 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 299
LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
Sbjct: 241 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 300
Query: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 359
QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
Sbjct: 301 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 360
Query: 360 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 419
TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
Sbjct: 361 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 420
Query: 420 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 479
ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
Sbjct: 421 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 480
Query: 480 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 539
NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
Sbjct: 481 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 540
Query: 540 DAGQE 544
DAGQE
Sbjct: 541 DAGQE 545
>gi|58761484 chaperonin containing TCP1, subunit 3 isoform c [Homo
sapiens]
Length = 507
Score = 966 bits (2498), Expect = 0.0
Identities = 506/545 (92%), Positives = 506/545 (92%), Gaps = 39/545 (7%)
Query: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMT 60
MMGHRPVLVLSQNTKRESGRKVQSGNINAAK
Sbjct: 1 MMGHRPVLVLSQNTKRESGRKVQSGNINAAK----------------------------- 31
Query: 61 NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPT 119
IQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL GEMLSVAEHFLEQQMHPT
Sbjct: 32 ---------IQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQMHPT 82
Query: 120 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 179
VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV
Sbjct: 83 VVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 142
Query: 180 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 239
KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL
Sbjct: 143 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 202
Query: 240 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 299
LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA
Sbjct: 203 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 262
Query: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 359
QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF
Sbjct: 263 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 322
Query: 360 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 419
TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH
Sbjct: 323 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 382
Query: 420 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 479
ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV
Sbjct: 383 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 442
Query: 480 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 539
NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP
Sbjct: 443 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAP 502
Query: 540 DAGQE 544
DAGQE
Sbjct: 503 DAGQE 507
>gi|38455427 chaperonin containing TCP1, subunit 4 (delta) [Homo
sapiens]
Length = 539
Score = 300 bits (768), Expect = 2e-81
Identities = 177/515 (34%), Positives = 301/515 (58%), Gaps = 11/515 (2%)
Query: 16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75
R+ +++ NI+AAK +AD IRT LGPK M KM+ D G + +TNDG IL+++QV HP
Sbjct: 27 RDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHP 86
Query: 76 AAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 134
AA+ ++E+S+ QD E GDGTTSV+I+ G +L L++ +HPT++ +++KAL+ I
Sbjct: 87 AARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIE 146
Query: 135 TLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDI 194
L +S PV++SD + +LN +S+ +K +S++SSL ++++AV V + +D+
Sbjct: 147 ILTDMSRPVELSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKV-IDPATATSVDL 205
Query: 195 KKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTD 254
+ V+K+ GG I+D ++ G+++ + V++ + R ++ +I L+ L K +
Sbjct: 206 RDIKIVKKL-GGTIDDCELVEGLVLTQKVSNSGITR-VEKAKIGLIQFCLSAPKTDMDNQ 263
Query: 255 IEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGI-----SDLAQHYLMRANIT 309
I ++ R+L+ E YI L + I + +V++ +K I SDLA H+L + I
Sbjct: 264 IVVSDYAQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIM 323
Query: 310 AIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDP- 368
I+ + + D I + G + V+ ++ D +G+ E+ G IT C P
Sbjct: 324 VIKDIEREDIEFICKTIGTKPVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPG 383
Query: 369 KACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAM 428
K TI++RG++K ++ E ER++ DA+ V R ++ L+ GGGA E+ +A LTE S+ +
Sbjct: 384 KTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTL 443
Query: 429 TGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVD 488
+G+E + RA A A+EVIP TL +N G + I +T LR +H Q +T G+N G + +
Sbjct: 444 SGMESYCVRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGE-KTAGINVRKGGISN 502
Query: 489 MKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVS 523
+ E + +PL V + A ET +L+IDD+V+
Sbjct: 503 ILEELVVQPLLVSVSALTLATETVRSILKIDDVVN 537
>gi|24307939 chaperonin containing TCP1, subunit 5 (epsilon) [Homo
sapiens]
Length = 541
Score = 294 bits (753), Expect = 1e-79
Identities = 178/535 (33%), Positives = 309/535 (57%), Gaps = 15/535 (2%)
Query: 5 RPVLVLSQNTKRES--GRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTND 62
RP L++ ++ G + +I AAK +A+ +RT LGP + KM++D G + +TND
Sbjct: 14 RPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTND 73
Query: 63 GNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPTVV 121
G IL + V H AK M+E+S++QD+E+GDGTT V++L G +L AE L++ +HP +
Sbjct: 74 GATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRI 133
Query: 122 ISAYRKALDDMISTLKKIS--IPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAV 179
Y +A I L KIS + VDI D++ ++ +++ +K ++ IA++AV
Sbjct: 134 ADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAV 193
Query: 180 KMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVL 239
V E R+++D + +VE GG +ED+ +++GV+++KD +HP+M + +++ +I +
Sbjct: 194 LTVADME--RRDVDFE-LIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAI 250
Query: 240 LDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 299
L E K +++ +++T ED+ + + E+E +++ + I + ++ I + G D A
Sbjct: 251 LTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEA 310
Query: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD--E 357
H L++ N+ A+R V + IA A G RIV R EL + +G AGL++ G +
Sbjct: 311 NHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGF-AGLVQEISFGTTKD 369
Query: 358 YFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAV 417
I CK+ +A TI +RG +K I+ E +R+L DA+ V RN++ D ++V GGGA+E++
Sbjct: 370 KMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISC 429
Query: 418 AHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETW 477
A A+++++ +EQ+ RA A ALEVIP L +N G + I+ +T +RA+ +E
Sbjct: 430 ALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPAL 489
Query: 478 GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQ 532
G++ DMK+ + E L K Q A + ++L+IDDI +K G+ +
Sbjct: 490 GIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDI----RKPGESE 540
>gi|5453607 chaperonin containing TCP1, subunit 7 isoform a [Homo
sapiens]
Length = 543
Score = 284 bits (727), Expect = 1e-76
Identities = 172/547 (31%), Positives = 286/547 (52%), Gaps = 19/547 (3%)
Query: 6 PVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNA 65
PV++L + T G NI+A + IA+ +RT LGP+ M K+++D G ++NDG
Sbjct: 5 PVILLKEGTDSSQGIPQLVSNISACQVIAEAVRTTLGPRGMDKLIVDGRGKATISNDGAT 64
Query: 66 ILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILG-EMLSVAEHFLEQQMHPTVVISA 124
IL+ + V HPAAK++++I+++QD EVGDGTTSV +L E L + ++E+ +HP ++I A
Sbjct: 65 ILKLLDVVHPAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLHPQIIIRA 124
Query: 125 YRKALDDMISTLKKISIPVDISDSDMMLNIIN----SSITTKAISRWSSLACNIALDAVK 180
+R A ++ +K+I++ V +D ++ +++++K IS+ + + +DAV
Sbjct: 125 FRTATQLAVNKIKEIAVTVKKADKVEQRKLLEKCAMTALSSKLISQQKAFFAKMVVDAVM 184
Query: 181 MVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIK---NPRI 237
M+ ++ K ++K+ GG +EDS ++ GV K ++ K NP+I
Sbjct: 185 MLD-------DLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKI 237
Query: 238 VLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISD 297
LL+ LE K + +I + ED+ I+ E + E I VV+++ I D
Sbjct: 238 ALLNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGD 297
Query: 298 LAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDE 357
+A Y ++ RV + D R ACG I + L D +G + E +IG E
Sbjct: 298 VATQYFADRDMFCAGRVPEEDLKRTMMACGGSIQTSVNALSADVLGR-CQVFEETQIGGE 356
Query: 358 YFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAV 417
+ F T C K CT +LRG +++ + E ER+L DA+ + R + + +V GGGA EM +
Sbjct: 357 RYNFFTGCPKAKTCTFILRGGAEQFMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMEL 416
Query: 418 AHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETW 477
+ L + S+ + G +Q A A+ALE+IPR L N G +L LRA+H Q TW
Sbjct: 417 SKYLRDYSRTIPGKQQLLIGAYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGG--TW 474
Query: 478 -GVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQG 536
GV+ + D E +WEP V++ A E A L++ +D+ + + D + G
Sbjct: 475 YGVDINNEDIADNFEAFVWEPAMVRINALTAASEAACLIVSVDETIKNPRSTVDAPTAAG 534
Query: 537 GAPDAGQ 543
G+
Sbjct: 535 RGRGRGR 541
>gi|57863257 T-complex protein 1 isoform a [Homo sapiens]
Length = 556
Score = 280 bits (717), Expect = 2e-75
Identities = 180/541 (33%), Positives = 296/541 (54%), Gaps = 18/541 (3%)
Query: 16 RESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHP 75
R +G ++S N+ AA +IA+I+++ LGP + KML+D +G + +TNDG IL+ ++V+HP
Sbjct: 11 RSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHP 70
Query: 76 AAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPTVVISAYRKALDDMIS 134
AAK + E++ QD+EVGDGTTSV+I+ E+L A+ ++Q++HPT VIS YR A + +
Sbjct: 71 AAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVR 130
Query: 135 TL-KKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEI 192
+ + + + D D ++N +S+++K I N+ +DAV +++ + G+
Sbjct: 131 YINENLIVNTDELGRDCLINAAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRY 190
Query: 193 DIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQ 252
+ + K G +S ++ G +N V M + I N +I LD SL+ K +
Sbjct: 191 PVNS-VNILKAHGRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLG 249
Query: 253 TDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIR 312
+ IT E +I Q E + ++ + I+ +V++T GI D+ Y + A A+R
Sbjct: 250 VQVVITDPEKLDQIRQRESDITKERIQKILATGANVILTTGGIDDMCLKYFVEAGAMAVR 309
Query: 313 RVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEI-----KKIGDEYFTFITDCKD 367
RV K D RIA+A GA I+S L ++ A L + ++I D+ I + K
Sbjct: 310 RVLKRDLKRIAKASGATILSTLANLEGEETFEAAMLGQAEEVVQERICDDELILIKNTKA 369
Query: 368 PKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKA 427
+ +I+LRGA+ + E+ER+L DA+ V + VL +VPGGGA E A++ L + +
Sbjct: 370 RTSASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGGAVEAALSIYLENYATS 429
Query: 428 MTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQ-------ENCETWGVN 480
M EQ A++L VIP TL N + L+ LRA H + +N + G++
Sbjct: 430 MGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLD 489
Query: 481 GETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPD 540
G D K+ G++EP VK+++ K A E A+ +LRIDD++ H + DD + G D
Sbjct: 490 LSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLIKLHPESKDD--KHGSYED 547
Query: 541 A 541
A
Sbjct: 548 A 548
>gi|4502643 chaperonin containing TCP1, subunit 6A isoform a [Homo
sapiens]
Length = 531
Score = 264 bits (675), Expect = 1e-70
Identities = 151/507 (29%), Positives = 290/507 (57%), Gaps = 17/507 (3%)
Query: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
NI+AA+ + D++RT LGPK MKML+ G I +T DGN +L E+Q+QHP A + +++
Sbjct: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVAT 82
Query: 86 TQDEEVGDGTTS-VIILGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVD 144
QD+ GDGTTS V+I+GE+L A+ ++ + +HP ++ + A + + L+++ + +
Sbjct: 83 AQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSRE 142
Query: 145 ISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIP 204
+ D + ++++ +S+ TK + + + +D++ ++ ++ + ID+ +E +
Sbjct: 143 M-DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EPIDLFMIEIME-MK 197
Query: 205 GGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFT 264
D+ ++RG++++ HP M++ +++ I+ + SLEY+K E + E+
Sbjct: 198 HKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEERE 257
Query: 265 RILQMEEEYIQQLCEDIIQLKPDV---------VITEKGISDLAQHYLMRANITAIRRVR 315
++++ E ++I+ + II+LK V VI +KGI + L + I A+RR +
Sbjct: 258 KLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAK 317
Query: 316 KTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 375
+ + R+ ACG ++ ++L D +G AGL+ +G+E FTFI C +P++ T+L+
Sbjct: 318 RRNMERLTLACGGVALNSFDDLSPDCLGH-AGLVYEYTLGEEKFTFIEKCNNPRSVTLLI 376
Query: 376 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 435
+G +K L++++ ++D ++ +N + D +VPG GA E+A+A AL + ++ G Q
Sbjct: 377 KGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLG 436
Query: 436 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 495
+A A AL +IP+ L QN G L ++A+H+ E+ + GV+ TG + E+G+W
Sbjct: 437 VQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-ESGQLVGVDLNTGEPMVAAEVGVW 495
Query: 496 EPLAVKLQTYKTAVETAVLLLRIDDIV 522
+ VK Q + A +L +D+I+
Sbjct: 496 DNYCVKKQLLHSCTVIATNILLVDEIM 522
>gi|58331173 chaperonin containing TCP1, subunit 6B [Homo sapiens]
Length = 530
Score = 258 bits (659), Expect = 1e-68
Identities = 156/523 (29%), Positives = 290/523 (55%), Gaps = 21/523 (4%)
Query: 13 NTKRE--SGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREI 70
N+K E R + NI AA+ + D++RT LGPK MKML+ G I +T DGN +L E+
Sbjct: 8 NSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLDEM 67
Query: 71 QVQHPAAKSMIEISRTQDEEVGDGTTS-VIILGEMLSVAEHFLEQQMHPTVVISAYRKAL 129
Q+QHP A + +++ QD+ GDGTTS V+I+GE+L A+ ++ + +HP ++ + A
Sbjct: 68 QIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAK 127
Query: 130 DDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGR 189
+ L+++ + ++ ++L++ +S+ TK + + + + +D+V V+ R
Sbjct: 128 IKALEVLEEVKVTKEMKRK-ILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR-----R 181
Query: 190 KEIDIKKY-ARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKK 248
I + + ++ + D+ +++G++++ HP M++ +++ I++ + SLEY+K
Sbjct: 182 PGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEK 241
Query: 249 GESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV---------VITEKGISDLA 299
E + E+ ++++ E ++I+ + II LK V VI +KGI +
Sbjct: 242 TEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFS 301
Query: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 359
L + I A+RR ++ + R++ ACG V+ E+L D +G AGL+ +G+E F
Sbjct: 302 LDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGH-AGLVYEYTLGEEKF 360
Query: 360 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 419
TFI +C +P + T+L++G +K L++V+ ++D ++ +N + D +VPG GA E+A+A
Sbjct: 361 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE 420
Query: 420 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGV 479
AL ++ G + +A A AL +IP+ L QN G L ++A+H E+ + GV
Sbjct: 421 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHV-ESKQLVGV 479
Query: 480 NGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV 522
+ TG + + G+W+ VK Q + A +L +D+I+
Sbjct: 480 DLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522
>gi|5453603 chaperonin containing TCP1, subunit 2 [Homo sapiens]
Length = 535
Score = 221 bits (563), Expect = 1e-57
Identities = 158/532 (29%), Positives = 274/532 (51%), Gaps = 21/532 (3%)
Query: 6 PVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPM--GGIVMTNDG 63
PV + E + + A I D++++ LGPK M K+LL +++TNDG
Sbjct: 8 PVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDASLMVTNDG 67
Query: 64 NAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILG-EMLSVAEHFLEQQMHPTVVI 122
IL+ I V +PAAK ++++SR QD+EVGDGTTSV +L E+L AE + +++HP +I
Sbjct: 68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTII 127
Query: 123 SAYRKALDDMISTLKKISIPVDISDSDM-----MLNIINSSITTKAISRWSSLACNIALD 177
+ +R+A L +S VD ++ ++NI +++++K ++ +A++
Sbjct: 128 AGWREATKAAREAL--LSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVE 185
Query: 178 AVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRI 237
AV ++ N IKK GG + DS + G +++K + + +R I+N +I
Sbjct: 186 AVLRLKGSGNLEAIHIIKKL-------GGSLADSYLDEGFLLDKKIGVNQPKR-IENAKI 237
Query: 238 VLLDSSLEYKKGES-QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGIS 296
++ ++ ++ K + + + + I E+E +++ E I++ + I + I
Sbjct: 238 LIANTGMDTDKIKIFGSRVRVDSTAKVAEIEHAEKEKMKEKVERILKHGINCFINRQLIY 297
Query: 297 DLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD 356
+ + A + AI R+A G I S + +G+ L+E IG+
Sbjct: 298 NYPEQLFGAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGS-CKLIEEVMIGE 356
Query: 357 EYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMA 416
+ + +ACTI+LRGA+++IL E ER+L DA+ V + D + V GGG SEM
Sbjct: 357 DKLIHFSGVALGEACTIVLRGATQQILDEAERSLHDALCVLAQTVKDSRTVYGGGCSEML 416
Query: 417 VAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCET 476
+AHA+T+ + G E + A+AL ++P + N G + L+ LRA H++ N T
Sbjct: 417 MAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGN-TT 475
Query: 477 WGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKK 528
G++ GT+ DM LGI E VK Q +A E A ++LR+D+I+ +K
Sbjct: 476 AGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIKAAPRK 527
>gi|48762932 chaperonin containing TCP1, subunit 8 (theta) [Homo
sapiens]
Length = 548
Score = 212 bits (540), Expect = 6e-55
Identities = 161/546 (29%), Positives = 263/546 (48%), Gaps = 33/546 (6%)
Query: 9 VLSQNTKRESG-RKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAIL 67
+L + K SG + NI A K +A RT GP M KM+++ + + +TND IL
Sbjct: 14 MLKEGAKHFSGLEEAVYRNIQACKELAQTTRTAYGPNGMNKMVINHLEKLFVTNDAATIL 73
Query: 68 REIQVQHPAAKSMIEISRTQDEEVGDGTTSVIIL-GEMLSVAEHFLEQQMHPTVVISAYR 126
RE++VQHPAAK ++ S Q++EVGDGT V++ G +L +AE L + + VI Y
Sbjct: 74 RELEVQHPAAKMIVMASHMQEQEVGDGTNFVLVFAGALLELAEELLRIGLSVSEVIEGYE 133
Query: 127 KALDDMISTLKKISI--PVDISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQF 184
A L + ++ D D + +++ +SI +K LA IA V + F
Sbjct: 134 IACRKAHEILPNLVCCSAKNLRDIDEVSSLLRTSIMSKQYGNEVFLAKLIAQACVSI--F 191
Query: 185 EENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINK----DVTHPRMRRYIKNPRIVLL 240
++G +D RV KI G I S VL G++ K DVT +K+ +I +
Sbjct: 192 PDSGHFNVD---NIRVCKILGSGISSSSVLHGMVFKKETEGDVTS------VKDAKIAVY 242
Query: 241 DSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQ 300
+ E++ + I E+ + EE + + I +VV+T ++D+A
Sbjct: 243 SCPFDGMITETKGTVLIKTAEELMNFSKGEENLMDAQVKAIADTGANVVVTGGKVADMAL 302
Query: 301 HYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGD-EYF 359
HY + NI +R K D R+ + GA + R +++G + + ++GD +
Sbjct: 303 HYANKYNIMLVRLNSKWDLRRLCKTVGATALPRLTPPVLEEMGH-CDSVYLSEVGDTQVV 361
Query: 360 TFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAH 419
F + +D TI+LRG++ ++ ++ER + D + + + D +LVPGGGA+E+ +A
Sbjct: 362 VFKHEKEDGAISTIVLRGSTDNLMDDIERAVDDGVNTFKVLTRDKRLVPGGGATEIELAK 421
Query: 420 ALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCET-WG 478
+T + G+EQ+ + A+A E IPR L +N G +++ L A H + N
Sbjct: 422 QITSYGETCPGLEQYAIKKFAEAFEAIPRALAENSGVKANEVISKLYAVHQEGNKNVGLD 481
Query: 479 VNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIV-----------SGHKK 527
+ E + DM E GI + K K A AV +LR+D I+ SG K
Sbjct: 482 IEAEVPAVKDMLEAGILDTYLGKYWAIKLATNAAVTVLRVDQIIMAKPAGGPKPPSGKKD 541
Query: 528 KGDDQS 533
DDQ+
Sbjct: 542 WDDDQN 547
>gi|58331171 chaperonin containing TCP1, subunit 6A isoform b [Homo
sapiens]
Length = 486
Score = 204 bits (519), Expect = 2e-52
Identities = 132/506 (26%), Positives = 258/506 (50%), Gaps = 60/506 (11%)
Query: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
NI+AA+ + D++RT LGPK MKML+ G I +T DGN +L E+
Sbjct: 23 NISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMG-------------- 68
Query: 86 TQDEEVGDGTTSVIILGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPVDI 145
+HP ++ + A + + L+++ + ++
Sbjct: 69 ------------------------------LHPRIITEGFEAAKEKALQFLEEVKVSREM 98
Query: 146 SDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPG 205
D + ++++ +S+ TK + + + +D++ ++ ++ + ID+ +E +
Sbjct: 99 -DRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQD---EPIDLFMIEIME-MKH 153
Query: 206 GIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTR 265
D+ ++RG++++ HP M++ +++ I+ + SLEY+K E + E+ +
Sbjct: 154 KSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREK 213
Query: 266 ILQMEEEYIQQLCEDIIQLKPDV---------VITEKGISDLAQHYLMRANITAIRRVRK 316
+++ E ++I+ + II+LK V VI +KGI + L + I A+RR ++
Sbjct: 214 LVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKR 273
Query: 317 TDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLR 376
+ R+ ACG ++ ++L D +G AGL+ +G+E FTFI C +P++ T+L++
Sbjct: 274 RNMERLTLACGGVALNSFDDLSPDCLGH-AGLVYEYTLGEEKFTFIEKCNNPRSVTLLIK 332
Query: 377 GASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPY 436
G +K L++++ ++D ++ +N + D +VPG GA E+A+A AL + ++ G Q
Sbjct: 333 GPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGV 392
Query: 437 RAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIWE 496
+A A AL +IP+ L QN G L ++A+H+ E+ + GV+ TG + E+G+W+
Sbjct: 393 QAFADALLIIPKVLAQNSGFDLQETLVKIQAEHS-ESGQLVGVDLNTGEPMVAAEVGVWD 451
Query: 497 PLAVKLQTYKTAVETAVLLLRIDDIV 522
VK Q + A +L +D+I+
Sbjct: 452 NYCVKKQLLHSCTVIATNILLVDEIM 477
>gi|57863259 T-complex protein 1 isoform b [Homo sapiens]
Length = 401
Score = 167 bits (424), Expect = 2e-41
Identities = 121/396 (30%), Positives = 198/396 (50%), Gaps = 16/396 (4%)
Query: 159 ITTKAISRWSSLACNIALDAVKMVQFEE-NGRKEIDIKKYARVEKIPGGIIEDSCVLRGV 217
+++K I N+ +DAV +++ + G+ + + K G +S ++ G
Sbjct: 1 MSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNS-VNILKAHGRSQMESMLISGY 59
Query: 218 MINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQL 277
+N V M + I N +I LD SL+ K + + IT E +I Q E + ++
Sbjct: 60 ALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKER 119
Query: 278 CEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEEL 337
+ I+ +V++T GI D+ Y + A A+RRV K D RIA+A GA I+S L
Sbjct: 120 IQKILATGANVILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANL 179
Query: 338 REDDVGTGAGLLEIK-----KIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQD 392
++ A L + + +I D+ I + K + +I+LRGA+ + E+ER+L D
Sbjct: 180 EGEETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHD 239
Query: 393 AMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQ 452
A+ V + VL +VPGGGA E A++ L + +M EQ A++L VIP TL
Sbjct: 240 ALCVVKRVLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAV 299
Query: 453 NCGASTIRLLTSLRAKHTQ-------ENCETWGVNGETGTLVDMKELGIWEPLAVKLQTY 505
N + L+ LRA H + +N + G++ G D K+ G++EP VK+++
Sbjct: 300 NAAQDSTDLVAKLRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSL 359
Query: 506 KTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPDA 541
K A E A+ +LRIDD++ H + DD + G DA
Sbjct: 360 KFATEAAITILRIDDLIKLHPESKDD--KHGSYEDA 393
>gi|58331185 chaperonin containing TCP1, subunit 7 isoform b [Homo
sapiens]
Length = 339
Score = 163 bits (413), Expect = 3e-40
Identities = 104/338 (30%), Positives = 162/338 (47%), Gaps = 7/338 (2%)
Query: 210 DSCVLRGVMINKDVTHPRMRRYIK---NPRIVLLDSSLEYKKGESQTDIEITREEDFTRI 266
DS ++ GV K ++ K NP+I LL+ LE K + +I + ED+ I
Sbjct: 3 DSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIALLNVELELKAEKDNAEIRVHTVEDYQAI 62
Query: 267 LQMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC 326
+ E + E I VV+++ I D+A Y ++ RV + D R AC
Sbjct: 63 VDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFADRDMFCAGRVPEEDLKRTMMAC 122
Query: 327 GARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEV 386
G I + L D +G + E +IG E + F T C K CT +LRG +++ + E
Sbjct: 123 GGSIQTSVNALSADVLGR-CQVFEETQIGGERYNFFTGCPKAKTCTFILRGGAEQFMEET 181
Query: 387 ERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVI 446
ER+L DA+ + R + + +V GGGA EM ++ L + S+ + G +Q A A+ALE+I
Sbjct: 182 ERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIPGKQQLLIGAYAKALEII 241
Query: 447 PRTLIQNCGASTIRLLTSLRAKHTQENCETW-GVNGETGTLVDMKELGIWEPLAVKLQTY 505
PR L N G +L LRA+H Q TW GV+ + D E +WEP V++
Sbjct: 242 PRQLCDNAGFDATNILNKLRARHAQGG--TWYGVDINNEDIADNFEAFVWEPAMVRINAL 299
Query: 506 KTAVETAVLLLRIDDIVSGHKKKGDDQSRQGGAPDAGQ 543
A E A L++ +D+ + + D + G G+
Sbjct: 300 TAASEAACLIVSVDETIKNPRSTVDAPTAAGRGRGRGR 337
>gi|7657253 T-complex protein 1 [Homo sapiens]
Length = 557
Score = 154 bits (390), Expect = 2e-37
Identities = 128/513 (24%), Positives = 233/513 (45%), Gaps = 35/513 (6%)
Query: 26 NINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISR 85
++ A +T+A +IR C GP K L+ G V T AILR ++++HPAA + E +
Sbjct: 36 SLAAVQTLASVIRPCYGPHGRQKFLVTMKGETVCTGCATAILRALELEHPAAWLLREAGQ 95
Query: 86 TQDEEVGDGTTSVIILGE-MLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKISIPV- 143
TQ E GDGT V++L E +L AE L+ + + AY A ++++TL ++I
Sbjct: 96 TQAENSGDGTAFVVLLTEALLEQAEQLLKAGLPRPQLREAYATATAEVLATLPSLAIQSL 155
Query: 144 -DISDSDMMLNIINSSITTKAISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEK 202
+ D L+ + ++ T + + L + A A+K + + V
Sbjct: 156 GPLEDPSWALHSVMNTHTLSPMDHLTKLVAH-ACWAIKELDGSFKPER-------VGVCA 207
Query: 203 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREED 262
+PGG +EDSC+L G+ I+ + +M + R+ L + ++ D
Sbjct: 208 LPGGTLEDSCLLPGLAISGKLCG-QMATVLSGARVALFACPFGPAHPNAPATARLSSPAD 266
Query: 263 FTRIL----QMEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLM-----RANITAIRR 313
+ Q+ E+ + QL I + + ++ LA Y + R+ + I
Sbjct: 267 LAQFSKGSDQLLEKQVGQLAAAGINVAVVLGEVDEETLTLADKYGIVVIQARSWMEIIYL 326
Query: 314 VRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTI 373
D + R + + + + ++G G ++ F +C A T+
Sbjct: 327 SEVLDTPLLPRLLPPQRPGKCQRVYRQELGDGLAVV-----------FEWECTGTPALTV 375
Query: 374 LLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQ 433
+LRGA+ + L E+ + + + DP+L+PG GA+EMA+A L++K + G
Sbjct: 376 VLRGATTQGLRSAEQAVYHGIDAYFQLCQDPRLIPGAGATEMALAKMLSDKGSRLEGPSG 435
Query: 434 WPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELG 493
+ A A AL+ +P+TL +N G + ++ + H N GV T ++++ + G
Sbjct: 436 PAFLAFAWALKYLPKTLAENAGLAVSDVMAEMSGVHQGGNL-LMGVG--TEGIINVAQEG 492
Query: 494 IWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHK 526
+W+ L VK Q ++ E + L+ +D+IV K
Sbjct: 493 VWDTLIVKAQGFRAVAEVVLQLVTVDEIVVAKK 525
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 98.6 bits (244), Expect = 1e-20
Identities = 68/232 (29%), Positives = 119/232 (51%), Gaps = 12/232 (5%)
Query: 165 SRWSSLACNIALDAVKMVQFE-ENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDV 223
S W + ++ V+ V+ + +N ++DI+++ ++KIPGG DS V+ G + K++
Sbjct: 631 SSWRDIIVSLVCQVVQTVRPDVKNQDDDMDIRQFVHIKKIPGGKKFDSVVVNGFVCTKNI 690
Query: 224 THPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQ 283
H +M IKNP+I+LL S+EY E T+ I+ E E+++ + I+
Sbjct: 691 AHKKMSSCIKNPKILLLKCSIEYLYREE------TKFTCIDPIVLQEREFLKNYVQRIVD 744
Query: 284 LKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARAC-GARIVSRPEELREDDV 342
++P +V+ EK +S +AQ L+ IT + V+ RI+R G ++S + L + +
Sbjct: 745 VRPTLVLVEKTVSRIAQDMLLEHGITLVINVKSQVLERISRMTQGDLVMSMDQLLTKPHL 804
Query: 343 GT-GAGLLEIKKIGDEY---FTFITDCKDPKACTILLRGASKEILSEVERNL 390
GT ++I ++ +E F C CTI LRG S L+ V+ L
Sbjct: 805 GTCHKFYMQIFQLPNEQTKTLMFFEGCPQHLGCTIKLRGGSDYELARVKEIL 856
>gi|9055272 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 75.9 bits (185), Expect = 9e-14
Identities = 89/401 (22%), Positives = 165/401 (41%), Gaps = 18/401 (4%)
Query: 36 IIRTCLGPKSMMKMLLDPMGGIVMT-NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDG 94
I+ +C GP +K L + GG V T + +A+L + V HP K + + D
Sbjct: 32 IVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDC 91
Query: 95 TTSVIILGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKIS----IPVDISDSDM 150
IL ++ E+ + PT VI + L IS LK + IPVD S + +
Sbjct: 92 GLFTAIL--CCNLIENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQI 149
Query: 151 MLNIINSSITTKA---ISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGI 207
+L ++ S +T+K ++R + + + ++ EN I + K + + + G
Sbjct: 150 LLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGK-SLIVPLKGQR 208
Query: 208 IEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRIL 267
+ DS VL G++I IK + + G++ E T + +
Sbjct: 209 VIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYG--V 266
Query: 268 QMEEEYIQQLCE---DIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIAR 324
+E + QL +I D+V+ +K I + +L I AI R+ T + +
Sbjct: 267 SLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTK 326
Query: 325 ACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILS 384
G + + + + G+ + K +F I + + C++LL +
Sbjct: 327 MTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFHLIPN--EATICSLLLCNRNDTAWD 384
Query: 385 EVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKS 425
E++ Q A+ V + L +P + GGG +E +A + K+
Sbjct: 385 ELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKT 425
>gi|25914754 McKusick-Kaufman syndrome protein [Homo sapiens]
Length = 570
Score = 75.9 bits (185), Expect = 9e-14
Identities = 89/401 (22%), Positives = 165/401 (41%), Gaps = 18/401 (4%)
Query: 36 IIRTCLGPKSMMKMLLDPMGGIVMT-NDGNAILREIQVQHPAAKSMIEISRTQDEEVGDG 94
I+ +C GP +K L + GG V T + +A+L + V HP K + + D
Sbjct: 32 IVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDC 91
Query: 95 TTSVIILGEMLSVAEHFLEQQMHPTVVISAYRKALDDMISTLKKIS----IPVDISDSDM 150
IL ++ E+ + PT VI + L IS LK + IPVD S + +
Sbjct: 92 GLFTAIL--CCNLIENVQRLGLTPTTVIRLNKHLLSLCISYLKSETCGCRIPVDFSSTQI 149
Query: 151 MLNIINSSITTKA---ISRWSSLACNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGI 207
+L ++ S +T+K ++R + + + ++ EN I + K + + + G
Sbjct: 150 LLCLVRSILTSKPACMLTRKETEHVSALILRAFLLTIPENAEGHIILGK-SLIVPLKGQR 208
Query: 208 IEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRIL 267
+ DS VL G++I IK + + G++ E T + +
Sbjct: 209 VIDSTVLPGILIEMSEVQLMRLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYG--V 266
Query: 268 QMEEEYIQQLCE---DIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRKTDNNRIAR 324
+E + QL +I D+V+ +K I + +L I AI R+ T + +
Sbjct: 267 SLENAVLDQLLNLGRQLISDHVDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTK 326
Query: 325 ACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILS 384
G + + + + G+ + K +F I + + C++LL +
Sbjct: 327 MTGTQPIGSLGSICPNSYGSVKDVCTAKFGSKHFFHLIPN--EATICSLLLCNRNDTAWD 384
Query: 385 EVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKS 425
E++ Q A+ V + L +P + GGG +E +A + K+
Sbjct: 385 ELKLTCQTALHVLQLTLKEPWALLGGGCTETHLAAYIRHKT 425
>gi|41399285 chaperonin [Homo sapiens]
Length = 573
Score = 55.8 bits (133), Expect = 1e-07
Identities = 124/576 (21%), Positives = 227/576 (39%), Gaps = 81/576 (14%)
Query: 5 RPVL-VLSQNTKRESGRKVQSGN------INAAKTIADIIRTCLGPKSMMKMLLDPMGGI 57
RPV VL+ + R + V+ G + +AD + +GPK ++ G
Sbjct: 12 RPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSP 71
Query: 58 VMTNDGNAILREIQVQHP----AAKSMIEISRTQDEEVGDGTTSVIILGEMLSVAEHF-- 111
+T DG + + I ++ AK + +++ +EE GDGTT+ +L ++ E F
Sbjct: 72 KVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIA-KEGFEK 130
Query: 112 LEQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLA 171
+ + +P + A+D +I+ LKK S PV + + I+++ K I
Sbjct: 131 ISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG------ 183
Query: 172 CNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRY 231
NI DA+K V GRK + K + IIE RG + + + ++
Sbjct: 184 -NIISDAMKKV-----GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKC 237
Query: 232 IKNPRIVLLDS-----------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQ 276
VLL +LE + + I + D T +L + +Q
Sbjct: 238 EFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQV 297
Query: 277 LC--------------EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTD 318
+ +D+ V E+G++ D+ H L + + + D
Sbjct: 298 VAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----D 353
Query: 319 NNRIARACG--ARIVSRPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 375
+ + + G A+I R +E+ E DV T E +K+ +E ++D + +
Sbjct: 354 DAMLLKGKGDKAQIEKRIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKV 406
Query: 376 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 435
G S ++E + + DA+ R ++ +V GGG + + AL + A ++
Sbjct: 407 GGTSDVEVNEKKDRVTDALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIG 464
Query: 436 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 495
+ + L++ T+ +N G SL + ++ G + G V+M E GI
Sbjct: 465 IEIIKRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGII 519
Query: 496 EPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDD 531
+P V A A LL + +V+ K+ D
Sbjct: 520 DPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKD 555
>gi|31542947 chaperonin [Homo sapiens]
Length = 573
Score = 55.8 bits (133), Expect = 1e-07
Identities = 124/576 (21%), Positives = 227/576 (39%), Gaps = 81/576 (14%)
Query: 5 RPVL-VLSQNTKRESGRKVQSGN------INAAKTIADIIRTCLGPKSMMKMLLDPMGGI 57
RPV VL+ + R + V+ G + +AD + +GPK ++ G
Sbjct: 12 RPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSP 71
Query: 58 VMTNDGNAILREIQVQHP----AAKSMIEISRTQDEEVGDGTTSVIILGEMLSVAEHF-- 111
+T DG + + I ++ AK + +++ +EE GDGTT+ +L ++ E F
Sbjct: 72 KVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIA-KEGFEK 130
Query: 112 LEQQMHPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLA 171
+ + +P + A+D +I+ LKK S PV + + I+++ K I
Sbjct: 131 ISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISAN-GDKEIG------ 183
Query: 172 CNIALDAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRY 231
NI DA+K V GRK + K + IIE RG + + + ++
Sbjct: 184 -NIISDAMKKV-----GRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKC 237
Query: 232 IKNPRIVLLDS-----------SLEYKKGESQTDIEITREED----FTRILQMEEEYIQQ 276
VLL +LE + + I + D T +L + +Q
Sbjct: 238 EFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQV 297
Query: 277 LC--------------EDIIQLKPDVVITEKGIS----DLAQHYLMRANITAIRRVRKTD 318
+ +D+ V E+G++ D+ H L + + + D
Sbjct: 298 VAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTK----D 353
Query: 319 NNRIARACG--ARIVSRPEELRED-DVGTGAGLLEIKKIGDEYFTFITDCKDPKACTILL 375
+ + + G A+I R +E+ E DV T E +K+ +E ++D + +
Sbjct: 354 DAMLLKGKGDKAQIEKRIQEIIEQLDVTTSE--YEKEKL-NERLAKLSD----GVAVLKV 406
Query: 376 RGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASEMAVAHALTEKSKAMTGVEQWP 435
G S ++E + + DA+ R ++ +V GGG + + AL + A ++
Sbjct: 407 GGTSDVEVNEKKDRVTDALNATR-AAVEEGIVLGGGCALLRCIPALDSLTPANED-QKIG 464
Query: 436 YRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENCETWGVNGETGTLVDMKELGIW 495
+ + L++ T+ +N G SL + ++ G + G V+M E GI
Sbjct: 465 IEIIKRTLKIPAMTIAKNAGVE-----GSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGII 519
Query: 496 EPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKKGDD 531
+P V A A LL + +V+ K+ D
Sbjct: 520 DPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKD 555
>gi|100816407 Bardet-Biedl syndrome 10 [Homo sapiens]
Length = 723
Score = 48.1 bits (113), Expect = 2e-05
Identities = 19/81 (23%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Query: 24 SGNINAAKTIADIIRT----CLGPKSMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKS 79
+G++ AA +A+++ C+GP+ + P G ++++ +G +L + ++HP A+
Sbjct: 8 AGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARM 67
Query: 80 MIEISRTQDEEVGDGTTSVII 100
+++ + ++ GDG + II
Sbjct: 68 IVDCVSSHLKKTGDGAKTFII 88
>gi|40217788 Bardet-Biedl syndrome 12 [Homo sapiens]
Length = 710
Score = 34.7 bits (78), Expect = 0.23
Identities = 36/149 (24%), Positives = 65/149 (43%), Gaps = 6/149 (4%)
Query: 203 IPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNP--RIVLLDSSL--EYKKGESQTDIEIT 258
+PG SCV G + V++ + + ++N RIVL++ L Y+ I
Sbjct: 320 LPGLPETSSCVCPGYITVVSVSNNPVIKELQNQPVRIVLIEGDLTENYRHLGFNKSANIK 379
Query: 259 REEDFTRILQ--MEEEYIQQLCEDIIQLKPDVVITEKGISDLAQHYLMRANITAIRRVRK 316
D R+ + EE + + + +IQ K ++V+ + +S+ + + I V
Sbjct: 380 TVLDSMRLQEDSSEELWANHVLQVLIQFKVNLVLVQGNVSERLIEKCINSKRLVIGSVNG 439
Query: 317 TDNNRIARACGARIVSRPEELREDDVGTG 345
+ A A GA V+ ++ ED VG G
Sbjct: 440 SVMQAFAEAAGAVQVAYITQVNEDCVGDG 468
>gi|14251207 MOV10-like 1 [Homo sapiens]
Length = 1211
Score = 31.6 bits (70), Expect = 1.9
Identities = 22/80 (27%), Positives = 34/80 (42%), Gaps = 1/80 (1%)
Query: 130 DDMISTLKKISIPVDISDSDMMLNIINSSITTKAIS-RWSSLACNIALDAVKMVQFEENG 188
D M + +S+P + SD +N +NS K SSL N + ENG
Sbjct: 326 DQMCPVVSFVSVPEKENSSDENINSLNSHTKNKTSQMSESSLVNNRGISPGDCTCKGENG 385
Query: 189 RKEIDIKKYARVEKIPGGII 208
K+ + + E PGG++
Sbjct: 386 EKDNILSRKQMTEPEPGGLV 405
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 252 QTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDVVITEKGISD-LAQHYLMRANITA 310
+ D+EI EE + LQ+E+E +QL + + +++ + E + D LAQ M + + A
Sbjct: 215 RNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQIRTMESGLEA 274
Query: 311 IRRVRKTDNNRI 322
+ R+ ++
Sbjct: 275 EKLQREVQEAQV 286
>gi|10190716 spindle pole body component 25 [Homo sapiens]
Length = 224
Score = 31.6 bits (70), Expect = 1.9
Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 16/130 (12%)
Query: 243 SLEYKKGESQTDIEITREEDFTR---ILQMEEEYIQQLCEDIIQLKPDVVITEKGISDLA 299
S++ K+ E ++ + + +R ++Q +++ + +L ++ K ++ + I DL
Sbjct: 48 SVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLK 107
Query: 300 QHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIKKIGDEYF 359
+ Y + I K + R+ R + + +L +D +G LEI+KI E
Sbjct: 108 EEYSRKKE--TISTANKANAERLKR------LQKSADLYKDRLG-----LEIRKIYGEKL 154
Query: 360 TFITDCKDPK 369
FI DPK
Sbjct: 155 QFIFTNIDPK 164
>gi|226246537 zinc finger protein 407 isoform 3 [Homo sapiens]
Length = 1660
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/91 (21%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 5 RPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGN 64
R +LVL + +R S G + I R G +M + + + T+D
Sbjct: 418 RNILVLGNSFRRRSSTFTLKGQAKKRFNLLGIKR---GTSETQRMYMKHLRTQMKTHDAE 474
Query: 65 AILREIQVQHPAAKSMIEISRTQDEEVGDGT 95
++L+ ++ + + S TQ+ E G G+
Sbjct: 475 SVLKHLEACSSVQRVCVTTSETQEAEQGQGS 505
>gi|226246535 zinc finger protein 407 isoform 2 [Homo sapiens]
Length = 1815
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/91 (21%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 5 RPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGN 64
R +LVL + +R S G + I R G +M + + + T+D
Sbjct: 418 RNILVLGNSFRRRSSTFTLKGQAKKRFNLLGIKR---GTSETQRMYMKHLRTQMKTHDAE 474
Query: 65 AILREIQVQHPAAKSMIEISRTQDEEVGDGT 95
++L+ ++ + + S TQ+ E G G+
Sbjct: 475 SVLKHLEACSSVQRVCVTTSETQEAEQGQGS 505
>gi|134133288 zinc finger protein 407 isoform 1 [Homo sapiens]
Length = 2248
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/91 (21%), Positives = 38/91 (41%), Gaps = 3/91 (3%)
Query: 5 RPVLVLSQNTKRESGRKVQSGNINAAKTIADIIRTCLGPKSMMKMLLDPMGGIVMTNDGN 64
R +LVL + +R S G + I R G +M + + + T+D
Sbjct: 418 RNILVLGNSFRRRSSTFTLKGQAKKRFNLLGIKR---GTSETQRMYMKHLRTQMKTHDAE 474
Query: 65 AILREIQVQHPAAKSMIEISRTQDEEVGDGT 95
++L+ ++ + + S TQ+ E G G+
Sbjct: 475 SVLKHLEACSSVQRVCVTTSETQEAEQGQGS 505
>gi|11968182 ribosomal protein S18 [Homo sapiens]
Length = 152
Score = 31.2 bits (69), Expect = 2.5
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 308 ITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAGLLEIK---KIGDEYFTFITD 364
ITAI+ V + + + R + R EL ED+V +++ KI D + D
Sbjct: 30 ITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKD 89
Query: 365 CKDPKACTILLRGASKEILSEVER 388
KD K +L G ++ ++ER
Sbjct: 90 VKDGKYSQVLANGLDNKLREDLER 113
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 30.4 bits (67), Expect = 4.3
Identities = 18/90 (20%), Positives = 45/90 (50%), Gaps = 4/90 (4%)
Query: 194 IKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQT 253
++K+ K+ G I+ V R K + + + +K P+ ++ ++ + KG +++
Sbjct: 291 LRKFNARRKLKGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHNATDGIKGSTES 350
Query: 254 DIEITREEDFTRILQMEEEYIQQLCEDIIQ 283
T +ED L++ ++ I ++ E +I+
Sbjct: 351 CNTTTEDED----LKVRKQEIIKITEQLIE 376
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,725,616
Number of Sequences: 37866
Number of extensions: 753280
Number of successful extensions: 2116
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2037
Number of HSP's gapped (non-prelim): 35
length of query: 544
length of database: 18,247,518
effective HSP length: 107
effective length of query: 437
effective length of database: 14,195,856
effective search space: 6203589072
effective search space used: 6203589072
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.