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Search of human proteins with 58219048
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
(166 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58219048 hairy and enhancer of split 5 [Homo sapiens] 335 1e-92
gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens] 80 8e-16
gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens] 79 2e-15
gi|145207994 hairy and enhancer of split 7 [Homo sapiens] 78 3e-15
gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens] 78 3e-15
gi|5031763 hairy and enhancer of split 1 [Homo sapiens] 78 4e-15
gi|7657154 hairy/enhancer-of-split related with YRPW motif-like ... 68 4e-12
gi|66912172 hairy and enhancer of split 3 [Homo sapiens] 67 7e-12
gi|105990528 hairy/enhancer-of-split related with YRPW motif 1 i... 62 2e-10
gi|105990526 hairy/enhancer-of-split related with YRPW motif 1 i... 62 3e-10
gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Ho... 57 6e-09
gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens] 54 6e-08
gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens] 52 3e-07
gi|13540521 basic helix-loop-helix domain containing, class B, 3... 49 3e-06
gi|71274142 HES/HEY-like transcription factor [Homo sapiens] 48 4e-06
gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens] 43 1e-04
gi|24497554 homeobox A13 [Homo sapiens] 38 0.005
gi|110832843 TBP-associated factor 4 [Homo sapiens] 36 0.017
gi|239047343 spermatogenesis and oogenesis specific basic helix-... 35 0.023
gi|39812378 RAN binding protein 9 [Homo sapiens] 35 0.023
gi|31745180 aryl hydrocarbon receptor nuclear translocator-like ... 35 0.038
gi|50345881 cytoplasmic polyadenylation element binding protein ... 35 0.038
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ... 34 0.066
gi|71852580 aryl hydrocarbon receptor nuclear translocator-like ... 34 0.066
gi|42716311 aryl hydrocarbon receptor nuclear translocator-like ... 34 0.066
gi|239752280 PREDICTED: similar to family with sequence similari... 34 0.066
gi|210032463 family with sequence similarity 48, member B2 [Homo... 34 0.066
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens] 34 0.066
gi|22748787 hypothetical protein LOC126695 [Homo sapiens] 34 0.066
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 33 0.086
>gi|58219048 hairy and enhancer of split 5 [Homo sapiens]
Length = 166
Score = 335 bits (859), Expect = 1e-92
Identities = 166/166 (100%), Positives = 166/166 (100%)
Query: 1 MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKAD 60
MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKAD
Sbjct: 1 MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKAD 60
Query: 61 ILEMAVSYLKHSKAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQ 120
ILEMAVSYLKHSKAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQ
Sbjct: 61 ILEMAVSYLKHSKAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQ 120
Query: 121 RPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGLWRPW 166
RPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGLWRPW
Sbjct: 121 RPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGLWRPW 166
>gi|10863967 hairy and enhancer of split 4 isoform 2 [Homo sapiens]
Length = 221
Score = 80.1 bits (196), Expect = 8e-16
Identities = 73/193 (37%), Positives = 91/193 (47%), Gaps = 41/193 (21%)
Query: 12 SPKEKNRLRKPVVEKMRRDRINSSIEQLKLL----LEQEFARHQPNSKLEKADILEMAVS 67
S E + KPV+EK RR RIN S+ QLK L L +E +RH SKLEKADILEM V
Sbjct: 30 SAAEHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRH---SKLEKADILEMTVR 86
Query: 68 Y---LKHSKAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLT--LHAASDTQMKLLYHF--- 119
+ L+ + A + ++ Y G+ CL E +FL +D + +LL H
Sbjct: 87 HLRSLRRVQVTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAAC 146
Query: 120 -------QRP----PAAPA-APAKEPKA------------PGAAPP--PALSAKATAAAA 153
+RP PAAPA APA E A P APP P L+ AA
Sbjct: 147 LRQLGPSRRPASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPR 206
Query: 154 AAHQPACGLWRPW 166
A Q G WRPW
Sbjct: 207 AGPQGPGGPWRPW 219
>gi|63055047 hairy and enhancer of split homolog 2 [Homo sapiens]
Length = 173
Score = 78.6 bits (192), Expect = 2e-15
Identities = 59/163 (36%), Positives = 75/163 (46%), Gaps = 12/163 (7%)
Query: 15 EKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAVSYLKHSK 73
E + KP++EK RR RIN S+ QLK L+ R N SKLEKAD+LEM V +L+
Sbjct: 12 ELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMTVRFLQELP 71
Query: 74 AFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASD--TQMKLLYHFQRPPAAP----- 126
A Y EGYS C+ + L + +LL H R A+
Sbjct: 72 ASSWPTAAPLPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRRAASATLDGG 131
Query: 127 -AAPAKEPKAPGAAPPPALSAKATAAAAAAHQPAC--GLWRPW 166
A + P AP AP A A+A + P C GLWRPW
Sbjct: 132 RAGDSSGPSAPAPAPASA-PEPASAPVPSPPSPPCGPGLWRPW 173
>gi|145207994 hairy and enhancer of split 7 [Homo sapiens]
Length = 225
Score = 78.2 bits (191), Expect = 3e-15
Identities = 58/151 (38%), Positives = 75/151 (49%), Gaps = 15/151 (9%)
Query: 18 RLRKPVVEKMRRDRINSSIEQLK-LLLEQEFARHQPNSKLEKADILEMAVSYLKHSKAFV 76
++ KP+VEK RRDRIN S+E+L+ LLLE+ ++ N KLEKA+ILE AV YL+
Sbjct: 14 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVE 73
Query: 77 AAAGPKSLHQD-------YSEGYSWCLQEAVQFLTLHAASDTQMKLLY---HFQRPPAAP 126
P+S QD Y G+ CL F H AS L+ H P P
Sbjct: 74 PPGVPRSPVQDAEALASCYLSGFRECLLRLAAF--AHDASPAARAQLFSALHGYLRPKPP 131
Query: 127 AAPAKEPKAPGAAPPPALSAKATAAAAAAHQ 157
+P+ P AP P+L A A A HQ
Sbjct: 132 RPKPVDPRPP--APRPSLDPAAPALGPALHQ 160
>gi|216548627 hairy and enhancer of split 4 isoform 1 [Homo sapiens]
Length = 247
Score = 78.2 bits (191), Expect = 3e-15
Identities = 71/184 (38%), Positives = 88/184 (47%), Gaps = 41/184 (22%)
Query: 21 KPVVEKMRRDRINSSIEQLKLL----LEQEFARHQPNSKLEKADILEMAVSY---LKHSK 73
KPV+EK RR RIN S+ QLK L L +E +RH SKLEKADILEM V + L+ +
Sbjct: 65 KPVMEKRRRARINESLAQLKTLILDALRKESSRH---SKLEKADILEMTVRHLRSLRRVQ 121
Query: 74 AFVAAAGPKSLHQDYSEGYSWCLQEAVQFLT--LHAASDTQMKLLYHF----------QR 121
A + ++ Y G+ CL E +FL +D + +LL H +R
Sbjct: 122 VTAALSADPAVLGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQLGPSRR 181
Query: 122 P----PAAPA-APAKEPKA------------PGAAPP--PALSAKATAAAAAAHQPACGL 162
P PAAPA APA E A P APP P L+ AA A Q G
Sbjct: 182 PASLSPAAPAEAPAPEVYAGRPLLPSLGGPFPLLAPPLLPGLTRALPAAPRAGPQGPGGP 241
Query: 163 WRPW 166
WRPW
Sbjct: 242 WRPW 245
>gi|5031763 hairy and enhancer of split 1 [Homo sapiens]
Length = 280
Score = 77.8 bits (190), Expect = 4e-15
Identities = 62/188 (32%), Positives = 88/188 (46%), Gaps = 35/188 (18%)
Query: 3 PSTVAVELLSPK---EKNRLRKPVVEKMRRDRINSSIEQLKLL----LEQEFARHQPNSK 55
P++V PK E + KP++EK RR RIN S+ QLK L L+++ +RH SK
Sbjct: 18 PASVNTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRH---SK 74
Query: 56 LEKADILEMAVSYLKH---SKAFVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQ 112
LEKADILEM V +L++ ++ A + S+ Y G+S C+ E +FL+ +T+
Sbjct: 75 LEKADILEMTVKHLRNLQRAQMTAALSTDPSVLGKYRAGFSECMNEVTRFLSTCEGVNTE 134
Query: 113 M--KLLYH--------------------FQRPPAAPAAPAKEPKAPGAAPPPALSAKATA 150
+ +LL H Q PP P P AP A PPP + A
Sbjct: 135 VRTRLLGHLANCMTQINAMTYPGQPHPALQAPPPPPPGPGGPQHAPFAPPPPLVPIPGGA 194
Query: 151 AAAAAHQP 158
A P
Sbjct: 195 APPPGGAP 202
>gi|7657154 hairy/enhancer-of-split related with YRPW motif-like
[Homo sapiens]
Length = 328
Score = 67.8 bits (164), Expect = 4e-12
Identities = 47/137 (34%), Positives = 75/137 (54%), Gaps = 10/137 (7%)
Query: 12 SPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK- 70
S + + R+ ++EK RRDRINSS+ +L+ L+ F + Q +SKLEKA++L+M V +LK
Sbjct: 39 SQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEK-QGSSKLEKAEVLQMTVDHLKM 97
Query: 71 -HSKAFVAAAGPKSLHQDY-SEGYSWCLQEAVQFLTL-----HAASDTQMKLLYHFQRPP 123
H+ ++L D+ S G+ CL E +++L + A +++LL H
Sbjct: 98 LHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL-NSY 156
Query: 124 AAPAAPAKEPKAPGAAP 140
AA P+ P P A P
Sbjct: 157 AAEMEPSPTPTGPLAFP 173
>gi|66912172 hairy and enhancer of split 3 [Homo sapiens]
Length = 186
Score = 67.0 bits (162), Expect = 7e-12
Identities = 56/178 (31%), Positives = 77/178 (43%), Gaps = 35/178 (19%)
Query: 24 VEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSKAFVAAAGPKS 83
+EK RR RIN S+EQLK LLE+ ++ KLEKADILE++V Y++ + + P
Sbjct: 1 MEKKRRARINVSLEQLKSLLEKHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVP 60
Query: 84 LHQDYSEGYSWCLQEAVQF--------------LTLHAASDTQMKLLYHFQRPPA--APA 127
+ G+ CL Q L +A+ + M Q PA P
Sbjct: 61 RGAEQPSGFRSCLPGVSQLLRRGDEVGSGLRCPLVPESAAGSTMDSAGLGQEAPALFRPC 120
Query: 128 APAKEPKAPGA----APPPAL----SAKATAAAAAAHQPACG-----------LWRPW 166
PA AP A +PPP L S ++A+ QPA +WRPW
Sbjct: 121 TPAVWAPAPAAGGPRSPPPLLLLPESLPGSSASVPPPQPASSRCAESPGLGLRVWRPW 178
>gi|105990528 hairy/enhancer-of-split related with YRPW motif 1
isoform a [Homo sapiens]
Length = 304
Score = 62.4 bits (150), Expect = 2e-10
Identities = 44/125 (35%), Positives = 75/125 (60%), Gaps = 13/125 (10%)
Query: 1 MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKAD 60
M+P+T + ++L+ K R+ ++EK RRDRIN+S+ +L+ L+ F + Q ++KLEKA+
Sbjct: 39 MSPTTSS-QILARKR----RRGIIEKRRRDRINNSLSELRRLVPSAFEK-QGSAKLEKAE 92
Query: 61 ILEMAVSYLK--HSKAFVAAAGPKSLHQDY-SEGYSWCLQEAVQFLT----LHAASDTQM 113
IL+M V +LK H+ +L DY S G+ CL E ++L+ L A+ ++
Sbjct: 93 ILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRV 152
Query: 114 KLLYH 118
+L+ H
Sbjct: 153 RLVSH 157
>gi|105990526 hairy/enhancer-of-split related with YRPW motif 1
isoform b [Homo sapiens]
Length = 308
Score = 61.6 bits (148), Expect = 3e-10
Identities = 44/128 (34%), Positives = 75/128 (58%), Gaps = 15/128 (11%)
Query: 1 MAPSTVAVELLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFAR---HQPNSKLE 57
M+P+T + ++L+ K R+ ++EK RRDRIN+S+ +L+ L+ F + Q ++KLE
Sbjct: 39 MSPTTSS-QILARKR----RRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLE 93
Query: 58 KADILEMAVSYLK--HSKAFVAAAGPKSLHQDY-SEGYSWCLQEAVQFLT----LHAASD 110
KA+IL+M V +LK H+ +L DY S G+ CL E ++L+ L A+
Sbjct: 94 KAEILQMTVDHLKMLHTAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDP 153
Query: 111 TQMKLLYH 118
+++L+ H
Sbjct: 154 LRVRLVSH 161
>gi|6912414 hairy/enhancer-of-split related with YRPW motif 2 [Homo
sapiens]
Length = 337
Score = 57.4 bits (137), Expect = 6e-09
Identities = 39/110 (35%), Positives = 66/110 (60%), Gaps = 16/110 (14%)
Query: 20 RKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSKAFVAAA 79
R+ ++EK RRDRIN+S+ +L+ L+ F + Q ++KLEKA+IL+M V +LK + A
Sbjct: 52 RRGIIEKRRRDRINNSLSELRRLVPTAFEK-QGSAKLEKAEILQMTVDHLK----MLQAT 106
Query: 80 GPK------SLHQDY-SEGYSWCLQEAVQFLT----LHAASDTQMKLLYH 118
G K +L D+ S G+ CL E ++L+ L ++ +++L+ H
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSH 156
>gi|21361763 hairy and enhancer of split 6 isoform a [Homo sapiens]
Length = 224
Score = 53.9 bits (128), Expect = 6e-08
Identities = 56/202 (27%), Positives = 81/202 (40%), Gaps = 57/202 (28%)
Query: 18 RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK---HSKA 74
+ RKP+VEK RR RIN S+++L+LLL A + +KLE A++LE+ V ++ +A
Sbjct: 27 KARKPLVEKKRRARINESLQELRLLL----AGAEVQAKLENAEVLELTVRRVQGVLRGRA 82
Query: 75 FVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQM--KLLYH------------FQ 120
+ ++ GY C+ E F++ A D + +LL H FQ
Sbjct: 83 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQ 142
Query: 121 --------RPP-----------AAPAAPAKEPKAPG--------AAPPPALS-------- 145
PP AP +P P PG AP LS
Sbjct: 143 DLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPD 202
Query: 146 -AKATAAAAAAHQPACGLWRPW 166
A + Q A +WRPW
Sbjct: 203 LVPAALGSLTTAQIARSVWRPW 224
>gi|218751874 hairy and enhancer of split 6 isoform b [Homo sapiens]
Length = 222
Score = 51.6 bits (122), Expect = 3e-07
Identities = 55/202 (27%), Positives = 79/202 (39%), Gaps = 59/202 (29%)
Query: 18 RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK---HSKA 74
+ RKP+VEK RR RIN S+++L+LLL +KLE A++LE+ V ++ +A
Sbjct: 27 KARKPLVEKKRRARINESLQELRLLLA------GAEAKLENAEVLELTVRRVQGVLRGRA 80
Query: 75 FVAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQM--KLLYH------------FQ 120
+ ++ GY C+ E F++ A D + +LL H FQ
Sbjct: 81 REREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQ 140
Query: 121 --------RPP-----------AAPAAPAKEPKAPG--------AAPPPALS-------- 145
PP AP +P P PG AP LS
Sbjct: 141 DLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPD 200
Query: 146 -AKATAAAAAAHQPACGLWRPW 166
A + Q A +WRPW
Sbjct: 201 LVPAALGSLTTAQIARSVWRPW 222
>gi|13540521 basic helix-loop-helix domain containing, class B, 3
[Homo sapiens]
Length = 482
Score = 48.5 bits (114), Expect = 3e-06
Identities = 46/169 (27%), Positives = 70/169 (41%), Gaps = 26/169 (15%)
Query: 14 KEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK--- 70
K+ +L ++EK RRDRIN I QLK LL E + LEKA +LE+ + +LK
Sbjct: 42 KDTYKLPHRLIEKKRRDRINECIAQLKDLL-PEHLKLTTLGHLEKAVVLELTLKHLKALT 100
Query: 71 ------HSKAFVAAAGPKSLHQD-------YSEGYSWCLQEAVQFLTLHAASDTQ----M 113
H K G +SL + G+ C +E +Q+L+ + + +
Sbjct: 101 ALTEQQHQKIIALQNGERSLKSPIQSDLDAFHSGFQTCAKEVLQYLSRFESWTPREPRCV 160
Query: 114 KLLYHF-----QRPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQ 157
+L+ H Q P + P + G P A + A A Q
Sbjct: 161 QLINHLHAVATQFLPTPQLLTQQVPLSKGTGAPSAAGSAAAPCLERAGQ 209
Score = 27.7 bits (60), Expect = 4.7
Identities = 18/33 (54%), Positives = 19/33 (57%), Gaps = 2/33 (6%)
Query: 123 PAAPAAPAKEPKAPGAAPPPALSAKATAAAAAA 155
PAA AAP P P PA +A A AAAAAA
Sbjct: 378 PAAAAAPF--PLLYPGIPAPAAAAAAAAAAAAA 408
>gi|71274142 HES/HEY-like transcription factor [Homo sapiens]
Length = 327
Score = 47.8 bits (112), Expect = 4e-06
Identities = 53/200 (26%), Positives = 76/200 (38%), Gaps = 58/200 (29%)
Query: 15 EKNRLRKPV----VEKMRRDRINSSIEQLKLLLEQEFARH-------------------- 50
E++R+R PV +EK RRDRIN + +L + A+
Sbjct: 49 EESRVRTPVSHKVIEKRRRDRINRCLNELGKTVPMALAKQGEPQEALAQIRSRVRSLVLS 108
Query: 51 --------------------QPNSKLEKADILEMAVSYLK--HSKAFVAAAGPKSLHQDY 88
Q + KLEKA+ILEM V YL+ HS F L ++
Sbjct: 109 SATVPDQQALGRCEGPFLLLQSSGKLEKAEILEMTVQYLRALHSADFPRGREKAELLAEF 168
Query: 89 SE----GYSWCLQEAVQFLTLHAASDTQ----MKLLYHFQRPPAAPAAPAKEPKAPGAAP 140
+ GY C++ V +LT +T+ ++L Q A PA P G+ P
Sbjct: 169 ANYFHYGYHECMKNLVHYLTTVERMETKDTKYARILAFLQSKARLGAEPAFPPL--GSLP 226
Query: 141 PPALSAKATAAAA--AAHQP 158
P S + A A H P
Sbjct: 227 EPDFSYQLHPAGPEFAGHSP 246
>gi|4503299 basic helix-loop-helix family, member e40 [Homo sapiens]
Length = 412
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/115 (30%), Positives = 51/115 (44%), Gaps = 26/115 (22%)
Query: 14 KEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLKHSK 73
KE +L ++EK RRDRIN I QLK LL E + LEKA +LE+ LKH K
Sbjct: 50 KETYKLPHRLIEKKRRDRINECIAQLKDLL-PEHLKLTTLGHLEKAVVLELT---LKHVK 105
Query: 74 AF----------------------VAAAGPKSLHQDYSEGYSWCLQEAVQFLTLH 106
A ++ ++ + + G+ C +E +Q+L H
Sbjct: 106 ALTNLIDQQQQKIIALQSGLQAGELSGRNVETGQEMFCSGFQTCAREVLQYLAKH 160
>gi|24497554 homeobox A13 [Homo sapiens]
Length = 388
Score = 37.7 bits (86), Expect = 0.005
Identities = 23/49 (46%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 107 AASDTQMKLLYHFQRPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAA 155
AA++ L+ H P AP A + APG APP A +A A AAAAAA
Sbjct: 82 AAANQCRNLMAH--PAPLAPGAASAYSSAPGEAPPSAAAAAAAAAAAAA 128
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 35.8 bits (81), Expect = 0.017
Identities = 19/34 (55%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
Query: 123 PAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAH 156
P+ PAAPA P AP AAPPP A AT A H
Sbjct: 255 PSPPAAPA--PAAPAAAPPPPPPAPATLARPPGH 286
Score = 33.1 bits (74), Expect = 0.11
Identities = 20/42 (47%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 121 RPPAAPAAPAKEPKAPGAAPPPALSAK-ATAAAAAAHQPACG 161
RPP PA P P A A PPPA + +A AA A PA G
Sbjct: 282 RPPGHPAGP---PTAAPAVPPPAAAQNGGSAGAAPAPAPAAG 320
Score = 31.6 bits (70), Expect = 0.33
Identities = 17/37 (45%), Positives = 20/37 (54%)
Query: 123 PAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPA 159
PAAP + P GAA PPA +A + AA A PA
Sbjct: 231 PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267
Score = 28.5 bits (62), Expect = 2.8
Identities = 15/35 (42%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
Query: 124 AAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQP 158
A PAAPA+ APGAAP P + +A +P
Sbjct: 73 AGPAAPAE--GAPGAAPEPPPAGRARPGGGGPQRP 105
Score = 28.5 bits (62), Expect = 2.8
Identities = 16/38 (42%), Positives = 17/38 (44%)
Query: 122 PPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPA 159
PPAA P E A AP PA +A A A PA
Sbjct: 121 PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPA 158
Score = 28.5 bits (62), Expect = 2.8
Identities = 18/39 (46%), Positives = 18/39 (46%), Gaps = 3/39 (7%)
Query: 120 QRPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQP 158
Q PP AA P AP A PPA A A AAA P
Sbjct: 239 QTPPFVGAAA---PPAPAAPSPPAAPAPAAPAAAPPPPP 274
Score = 26.9 bits (58), Expect = 8.0
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 11/52 (21%)
Query: 122 PPAAPAAP----AKEPKAPGAAPPPALSAKATAA-------AAAAHQPACGL 162
P AAPA P A+ + GAAP PA +A A AAA PA G+
Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGV 342
>gi|239047343 spermatogenesis and oogenesis specific basic
helix-loop-helix 2 [Homo sapiens]
Length = 425
Score = 35.4 bits (80), Expect = 0.023
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 8/91 (8%)
Query: 11 LSPKEKNR---LRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVS 67
LS EKN+ L EK+RR+RI EQL+ LL R K + A +LE V
Sbjct: 193 LSEFEKNKKISLLHSSKEKLRRERIKYCCEQLRTLLPYVKGR-----KNDAASVLEATVD 247
Query: 68 YLKHSKAFVAAAGPKSLHQDYSEGYSWCLQE 98
Y+K+ + ++ A + + +C ++
Sbjct: 248 YVKYIREKISPAVMAQITEALQSNMRFCKKQ 278
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 35.4 bits (80), Expect = 0.023
Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 10/45 (22%)
Query: 122 PPAAPAAPAKEPKAP----------GAAPPPALSAKATAAAAAAH 156
PPA+ AAPA P AP G AP PAL A ++AAA H
Sbjct: 91 PPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPH 135
Score = 29.6 bits (65), Expect = 1.2
Identities = 17/38 (44%), Positives = 19/38 (50%), Gaps = 5/38 (13%)
Query: 122 PPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPA 159
PP P A A P P PPP A+AAA A+ PA
Sbjct: 72 PPPPPPATAAPPPPPPPPPPP-----ASAAAPASGPPA 104
>gi|31745180 aryl hydrocarbon receptor nuclear translocator-like 2
[Homo sapiens]
Length = 636
Score = 34.7 bits (78), Expect = 0.038
Identities = 21/51 (41%), Positives = 31/51 (60%), Gaps = 7/51 (13%)
Query: 25 EKMRRDRINSSIEQLKLLLEQ--EFARHQPNSKLEKADILEMAVSYLKHSK 73
EK RRD++N+ IE+L ++ Q AR KL+K +L MAV +L+ K
Sbjct: 116 EKRRRDKMNNLIEELSAMIPQCNPMAR-----KLDKLTVLRMAVQHLRSLK 161
>gi|50345881 cytoplasmic polyadenylation element binding protein 3
[Homo sapiens]
Length = 698
Score = 34.7 bits (78), Expect = 0.038
Identities = 21/53 (39%), Positives = 25/53 (47%), Gaps = 11/53 (20%)
Query: 117 YHFQRPPAAPAAPAKEPKAPGAAPPP-----------ALSAKATAAAAAAHQP 158
+H Q PP APA +P P A PP A A+ +AAAA HQP
Sbjct: 162 HHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQP 214
Score = 27.3 bits (59), Expect = 6.1
Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 19/63 (30%)
Query: 120 QRPPAAPAAPAKEPKAPGAAP-------------------PPALSAKATAAAAAAHQPAC 160
Q P A P + P +P AP P + SA A AAAAAA A
Sbjct: 180 QPPQAQPPQQRRSPASPSQAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSAS 239
Query: 161 GLW 163
W
Sbjct: 240 SSW 242
Score = 26.9 bits (58), Expect = 8.0
Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 119 FQRPPAAPAAPAKEPKAPGAAPPPALSA 146
F +PP P P +EP APGA+ P+ +
Sbjct: 83 FHQPPQQPPPP-QEPAAPGASLSPSFGS 109
>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
isoform b [Homo sapiens]
Length = 582
Score = 33.9 bits (76), Expect = 0.066
Identities = 18/47 (38%), Positives = 30/47 (63%), Gaps = 3/47 (6%)
Query: 24 VEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK 70
+EK RRD++NS I++L L+ + + KL+K +L MAV ++K
Sbjct: 37 IEKRRRDKMNSFIDELASLVP---TCNAMSRKLDKLTVLRMAVQHMK 80
>gi|71852580 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 33.9 bits (76), Expect = 0.066
Identities = 18/47 (38%), Positives = 30/47 (63%), Gaps = 3/47 (6%)
Query: 24 VEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK 70
+EK RRD++NS I++L L+ + + KL+K +L MAV ++K
Sbjct: 80 IEKRRRDKMNSFIDELASLVP---TCNAMSRKLDKLTVLRMAVQHMK 123
>gi|42716311 aryl hydrocarbon receptor nuclear translocator-like
isoform a [Homo sapiens]
Length = 625
Score = 33.9 bits (76), Expect = 0.066
Identities = 18/47 (38%), Positives = 30/47 (63%), Gaps = 3/47 (6%)
Query: 24 VEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKADILEMAVSYLK 70
+EK RRD++NS I++L L+ + + KL+K +L MAV ++K
Sbjct: 80 IEKRRRDKMNSFIDELASLVP---TCNAMSRKLDKLTVLRMAVQHMK 123
>gi|239752280 PREDICTED: similar to family with sequence similarity
48, member B2 [Homo sapiens]
Length = 779
Score = 33.9 bits (76), Expect = 0.066
Identities = 20/39 (51%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 122 PPAAPAAPAKEP-KAPGAAPPPALSAKATAAAAAAHQPA 159
P AAPA A P AP A PAL+A A AAAA P+
Sbjct: 456 PAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPS 494
>gi|210032463 family with sequence similarity 48, member B2 [Homo
sapiens]
Length = 817
Score = 33.9 bits (76), Expect = 0.066
Identities = 20/39 (51%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 122 PPAAPAAPAKEP-KAPGAAPPPALSAKATAAAAAAHQPA 159
P AAPA A P AP A PAL+A A AAAA P+
Sbjct: 494 PAAAPAVAAAAPAPAPAPAAAPALAAAAVAAAAGGAAPS 532
>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
Length = 887
Score = 33.9 bits (76), Expect = 0.066
Identities = 20/36 (55%), Positives = 21/36 (58%)
Query: 124 AAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPA 159
AA AA A A AAP PAL+A A A AAA PA
Sbjct: 502 AAAAAAAAAAAAAAAAPAPALAAAAAPALAAAAAPA 537
Score = 30.0 bits (66), Expect = 0.95
Identities = 19/36 (52%), Positives = 20/36 (55%)
Query: 124 AAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPA 159
AA AA A A AA PAL+A A A AAA PA
Sbjct: 510 AAAAAAAAPAPALAAAAAPALAAAAAPALAAAAAPA 545
Score = 29.6 bits (65), Expect = 1.2
Identities = 19/42 (45%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 122 PPAAPAAPAKEP-KAPGAAPPPALSAKATAAAAAAHQPACGL 162
PP +P K P A A A +A A AAAAAA PA L
Sbjct: 481 PPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPAL 522
Score = 29.6 bits (65), Expect = 1.2
Identities = 16/32 (50%), Positives = 19/32 (59%)
Query: 124 AAPAAPAKEPKAPGAAPPPALSAKATAAAAAA 155
AAPA A AP A PA++A AAA+AA
Sbjct: 534 AAPALAAAAAPAPAPAAAPAVAAAPAAAASAA 565
Score = 28.9 bits (63), Expect = 2.1
Identities = 17/34 (50%), Positives = 20/34 (58%), Gaps = 1/34 (2%)
Query: 123 PAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAH 156
PA AA A P AP AAP A + A A+AA +H
Sbjct: 536 PALAAAAAPAP-APAAAPAVAAAPAAAASAAPSH 568
Score = 27.7 bits (60), Expect = 4.7
Identities = 17/35 (48%), Positives = 18/35 (51%)
Query: 125 APAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPA 159
APA A A AA PAL+A A A A A PA
Sbjct: 519 APALAAAAAPALAAAAAPALAAAAAPAPAPAAAPA 553
>gi|22748787 hypothetical protein LOC126695 [Homo sapiens]
Length = 398
Score = 33.9 bits (76), Expect = 0.066
Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 121 RPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACG-LWRPW 166
+PP + +PK PG P +++ + +A A P C LWRPW
Sbjct: 35 QPPPSRRTRRPDPKDPGHHGPESITFISGSAEPALESPTCCLLWRPW 81
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 33.5 bits (75), Expect = 0.086
Identities = 20/53 (37%), Positives = 22/53 (41%), Gaps = 5/53 (9%)
Query: 118 HFQRPPAAPAAPAKEPKAPGAAPPPALSAKATA-----AAAAAHQPACGLWRP 165
H P P AP P APG PPP+ A AA A H A G+ P
Sbjct: 344 HPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPP 396
Score = 29.6 bits (65), Expect = 1.2
Identities = 17/48 (35%), Positives = 20/48 (41%), Gaps = 3/48 (6%)
Query: 118 HFQRPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGLWRP 165
H P P AP P APG PP ++ A H PA G+ P
Sbjct: 302 HPPAPGVHPPAPGVHPPAPGVHPP---TSGVHPPAPGVHPPAPGVHPP 346
Score = 28.9 bits (63), Expect = 2.1
Identities = 12/25 (48%), Positives = 13/25 (52%)
Query: 118 HFQRPPAAPAAPAKEPKAPGAAPPP 142
H Q P P AP P+APG P P
Sbjct: 387 HPQAPGVHPPAPGMHPQAPGVHPQP 411
Score = 28.5 bits (62), Expect = 2.8
Identities = 17/48 (35%), Positives = 18/48 (37%), Gaps = 10/48 (20%)
Query: 118 HFQRPPAAPAAPAKEPKAPGAAPPPALSAKATAAAAAAHQPACGLWRP 165
H P P AP P APG PP A H PA G+ P
Sbjct: 330 HPPAPGVHPPAPGVHPPAPGVHPP----------APGVHPPAPGVHPP 367
Score = 28.1 bits (61), Expect = 3.6
Identities = 17/48 (35%), Positives = 20/48 (41%), Gaps = 4/48 (8%)
Query: 122 PPAAPAAPAKEPKAPGAAPP-PALSAKATAA---AAAAHQPACGLWRP 165
P P P P APG PP P + A+ A H PA G+ P
Sbjct: 271 PSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPP 318
Score = 26.9 bits (58), Expect = 8.0
Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 112 QMKLLYHF--QRPPAAPAAPAKEPKAPGAAPP 141
Q L +HF ++PPA P+ PA P PP
Sbjct: 205 QFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPP 236
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.126 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,139,686
Number of Sequences: 37866
Number of extensions: 330726
Number of successful extensions: 7116
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 265
Number of HSP's successfully gapped in prelim test: 191
Number of HSP's that attempted gapping in prelim test: 5462
Number of HSP's gapped (non-prelim): 1606
length of query: 166
length of database: 18,247,518
effective HSP length: 95
effective length of query: 71
effective length of database: 14,650,248
effective search space: 1040167608
effective search space used: 1040167608
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.