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Search of human proteins with 5803203
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
(258 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 506 e-143
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 483 e-137
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 478 e-135
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 464 e-131
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 325 2e-89
gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 321 5e-88
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 315 2e-86
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 306 1e-83
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 305 3e-83
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 305 3e-83
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 301 4e-82
gi|148746195 trichohyalin [Homo sapiens] 73 3e-13
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 69 5e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 68 7e-12
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 67 1e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 2e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 67 2e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 64 1e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 64 1e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 64 1e-10
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 64 1e-10
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 64 2e-10
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 63 2e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 4e-10
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 62 5e-10
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 62 5e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 6e-10
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 61 8e-10
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 60 1e-09
gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 60 2e-09
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 506 bits (1302), Expect = e-143
Identities = 258/258 (100%), Positives = 258/258 (100%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR
Sbjct: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA
Sbjct: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
Query: 181 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK
Sbjct: 181 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
Query: 241 HSKKAGTPAKGKVGGRWK 258
HSKKAGTPAKGKVGGRWK
Sbjct: 241 HSKKAGTPAKGKVGGRWK 258
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 483 bits (1243), Expect = e-137
Identities = 250/258 (96%), Positives = 250/258 (96%), Gaps = 8/258 (3%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
MSDEEVEQVEEQYEEEEEAQEEEEVQE EEKPRPKLTAPKIPEGEKVDFDDIQ
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQE--------EEKPRPKLTAPKIPEGEKVDFDDIQ 52
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR
Sbjct: 53 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 112
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA
Sbjct: 113 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 172
Query: 181 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK
Sbjct: 173 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 232
Query: 241 HSKKAGTPAKGKVGGRWK 258
HSKKAGTPAKGKVGGRWK
Sbjct: 233 HSKKAGTPAKGKVGGRWK 250
>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
Length = 256
Score = 478 bits (1229), Expect = e-135
Identities = 249/259 (96%), Positives = 250/259 (96%), Gaps = 4/259 (1%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEE-EVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDI 59
MSDEEVEQVEEQYEEEEEAQEE EV E+ E EEKPRPKLTAPKIPEGEKVDFDDI
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEAAEVHEEVHEP---EEKPRPKLTAPKIPEGEKVDFDDI 57
Query: 60 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN 119
QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN
Sbjct: 58 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN 117
Query: 120 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 179
RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL
Sbjct: 118 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 177
Query: 180 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 239
AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ
Sbjct: 178 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 237
Query: 240 KHSKKAGTPAKGKVGGRWK 258
KHSKKAGTPAKGKVGGRWK
Sbjct: 238 KHSKKAGTPAKGKVGGRWK 256
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 464 bits (1194), Expect = e-131
Identities = 240/258 (93%), Positives = 243/258 (94%), Gaps = 8/258 (3%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
MSDEEVEQVEEQYEEEEEAQEEEEVQE EEKPRPKLTAPKIPEGEKVDFDDIQ
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQE--------EEKPRPKLTAPKIPEGEKVDFDDIQ 52
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR
Sbjct: 53 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 112
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA
Sbjct: 113 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 172
Query: 181 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDI +R+R+ K
Sbjct: 173 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIMNVRARVQMLAK 232
Query: 241 HSKKAGTPAKGKVGGRWK 258
SKKAGTPAKGKVGGRWK
Sbjct: 233 FSKKAGTPAKGKVGGRWK 250
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 325 bits (834), Expect = 2e-89
Identities = 168/265 (63%), Positives = 208/265 (78%), Gaps = 10/265 (3%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAE-EDAEEEKPRPK------LTAPKIPEGEK 53
MSD E ++ EE+ EEE A+EEEE E+ + EEE+P+P L PKIPEGE+
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
Query: 54 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 113
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
Query: 114 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 173
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
Query: 174 MKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRS 233
MK +IL+ER+KPL+ID++GE++LR+KA+EL + +HQLE +KF+ KLK+QKY+I L +
Sbjct: 181 MKVRILSERKKPLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYN 240
Query: 234 RIDQAQKHSKKAGTPAKGKVGGRWK 258
RI AQK K AG KG+VGGRWK
Sbjct: 241 RISHAQKFRKGAG---KGRVGGRWK 262
>gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens]
Length = 251
Score = 321 bits (822), Expect = 5e-88
Identities = 167/264 (63%), Positives = 205/264 (77%), Gaps = 19/264 (7%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPK------LTAPKIPEGEKV 54
MSD E ++ EE+ EEE A+EEEE EEE+P+P L PKIPEGE+V
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEE----------EEERPKPSRPVVPPLIPPKIPEGERV 50
Query: 55 DFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE 114
DFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EKE
Sbjct: 51 DFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE 110
Query: 115 RERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 174
RERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT REM
Sbjct: 111 RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREM 170
Query: 175 KKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSR 234
K +IL+ER+KPL+ID++GE++LR+KA+EL + +HQLE +KF+ KLK+QKY+I L +R
Sbjct: 171 KVRILSERKKPLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNR 230
Query: 235 IDQAQKHSKKAGTPAKGKVGGRWK 258
I AQK K AG KG+VGGRWK
Sbjct: 231 ISHAQKFRKGAG---KGRVGGRWK 251
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 315 bits (807), Expect = 2e-86
Identities = 168/281 (59%), Positives = 208/281 (74%), Gaps = 26/281 (9%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAE-EDAEEEKPRPK------LTAPKIPEGEK 53
MSD E ++ EE+ EEE A+EEEE E+ + EEE+P+P L PKIPEGE+
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
Query: 54 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 113
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
Query: 114 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 173
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
Query: 174 MKKKILAERRKPLNIDHLGEDKL----------------RDKAKELWETLHQLEIDKFEF 217
MK +IL+ER+KPL+ID++GE++L R+KA+EL + +HQLE +KF+
Sbjct: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
Query: 218 GEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 258
KLK+QKY+I L +RI AQK K AG KG+VGGRWK
Sbjct: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAG---KGRVGGRWK 278
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 306 bits (784), Expect = 1e-83
Identities = 167/278 (60%), Positives = 205/278 (73%), Gaps = 27/278 (9%)
Query: 4 EEVEQVEEQYEEEEEAQEEE-----EVQEDTAEEDAEEE---------------KPR--- 40
EE EQ E EE+EEA EE+ E +E AEED EEE KPR
Sbjct: 12 EEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFM 71
Query: 41 PKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRR 100
P L PKIP+GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RR
Sbjct: 72 PNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 131
Query: 101 AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAK 160
AERAEQQRIR E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ K
Sbjct: 132 AERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQK 190
Query: 161 ADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEK 220
++K GK+QT RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK
Sbjct: 191 TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEK 250
Query: 221 LKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 258
K+QKY+I LR+RI+ QK SK G K KV GRWK
Sbjct: 251 FKQQKYEINVLRNRINDNQKVSKTRG---KAKVTGRWK 285
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 305 bits (781), Expect = 3e-83
Identities = 165/288 (57%), Positives = 207/288 (71%), Gaps = 37/288 (12%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAE---------------------------- 35
EE EQ E EEEE+ +E+E+ QE+ AEEDAE
Sbjct: 12 EEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPME 71
Query: 36 EEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELV 90
E KP+P+ L PKIP+GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV
Sbjct: 72 ESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELV 131
Query: 91 ALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSM 150
+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M
Sbjct: 132 SLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM 191
Query: 151 GANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQL 210
++ Y+ K ++K GK+QT RE KKKILAERRK L IDHL ED+LR+KAKELW++++ L
Sbjct: 192 -MHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNL 250
Query: 211 EIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 258
E +KF+ EK K+QKY+I LR+RI+ QK SK G K KV GRWK
Sbjct: 251 EAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRG---KAKVTGRWK 295
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 305 bits (780), Expect = 3e-83
Identities = 166/284 (58%), Positives = 209/284 (73%), Gaps = 34/284 (11%)
Query: 5 EVEQVEEQYEEEEEAQEEEEVQEDT----------AEEDAEEE---------------KP 39
++E+V E+YEEEE+ ++EE +ED AEED EEE KP
Sbjct: 3 DIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP 62
Query: 40 R---PKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERI 96
R P L PKIP+GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RI
Sbjct: 63 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI 122
Query: 97 EKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSS 156
E+RRAERAEQQRIR E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++
Sbjct: 123 ERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGG 181
Query: 157 YLAKA--DQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDK 214
Y+ KA ++K GK+QT RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +K
Sbjct: 182 YIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEK 241
Query: 215 FEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 258
F+ EK K+QKY+I LR+RI+ QK SK G K KV GRWK
Sbjct: 242 FDLQEKFKQQKYEINVLRNRINDNQKVSKTRG---KAKVTGRWK 282
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 301 bits (771), Expect = 4e-82
Identities = 167/281 (59%), Positives = 206/281 (73%), Gaps = 30/281 (10%)
Query: 4 EEVEQVEEQYEEEEEAQEEE-----EVQEDTAEEDAEEE---------------KPR--- 40
EE EQ E EE+EEA EE+ E +E AEED EEE KPR
Sbjct: 12 EEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFM 71
Query: 41 PKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRR 100
P L PKIP+GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RR
Sbjct: 72 PNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 131
Query: 101 AERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYL-- 158
AERAEQQRIR E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+
Sbjct: 132 AERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQK 190
Query: 159 -AKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEF 217
A+ ++K GK+QT RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +KF+
Sbjct: 191 QAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDL 250
Query: 218 GEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 258
EK K+QKY+I LR+RI+ QK SK G K KV GRWK
Sbjct: 251 QEKFKQQKYEINVLRNRINDNQKVSKTRG---KAKVTGRWK 288
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 72.8 bits (177), Expect = 3e-13
Identities = 57/238 (23%), Positives = 119/238 (50%), Gaps = 11/238 (4%)
Query: 12 QYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKD---- 67
Q EEE+E ++ E V E+ EEE R + + + K++ +++++RQ ++
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 68 -LMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKA 126
L Q L E R++++EE +ER E++ R +Q R E+ RE+Q R +E+
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 127 RREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPL 186
RRE++ +R E++ ++++ L + Q R ++Q RE + + + R+
Sbjct: 359 RREQQ-LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 187 NIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 244
+ E +LR +E E H+ + ++ ++LKR++ + R ++ ++H ++
Sbjct: 418 QLRR--EQQLR---REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
Score = 69.3 bits (168), Expect = 3e-12
Identities = 66/257 (25%), Positives = 124/257 (48%), Gaps = 35/257 (13%)
Query: 7 EQVEEQYEEEEEAQEEEE-VQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 65
+++E QY +EEE Q+EEE + + E+ +E+ R + E E++ ++ Q R+
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERER------QCREEEELQQEEEQLLREE 1127
Query: 66 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAEE 124
++ Q L + E + ++EE L+E EKRR + E+Q R E ++E + L EE
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 125 -KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQK------------------R 165
+ RR+E + + R E++L+++K Y ++D K +
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQ----RYRDEDQRSDLKWQWEPEKENAVRDNKVYCK 1243
Query: 166 GKK-QTAREMKKKILAERRKPLNIDH-LGEDKLRDKAKELWETLHQLEIDKFEFGEKLKR 223
G++ + R+++ L +R+ ++ H LGE + RD+ +E Q F E+L+R
Sbjct: 1244 GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE--RRRWQQRDRHFPEEEQLER 1301
Query: 224 QKYDITTLRSRIDQAQK 240
++ R R Q +K
Sbjct: 1302 EEQKEAKRRDRKSQEEK 1318
Score = 62.0 bits (149), Expect = 5e-10
Identities = 59/247 (23%), Positives = 125/247 (50%), Gaps = 24/247 (9%)
Query: 3 DEEVEQVEEQ-----------YEEEEEAQEEEEVQEDTAEEDAEE-EKPRPKLTAPKIPE 50
D++++Q EEQ E E++ +EEEE+Q++ + EE EK R + + +
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 51 GEKVDFDDIQKKRQNKDLMELQALIDSHFEARK-KEEEELVALKERIEKRRAERAEQQRI 109
+++ ++ Q R+ ++ LQ + E + ++EEE + +ER +RR E Q R
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 110 RAEKERERQNRLAE--EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGK 167
E ++E + L E EK RR+E + + R E++L++++ + +++ +
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
Query: 168 KQTAREMKKKILAE-----RRKPLNIDHLGEDKLRDKAKEL----WETLHQLEIDKFEFG 218
++ ++ ++++L E RR+ L + E++L+ + ++L E Q ++
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Query: 219 EKLKRQK 225
E+L+RQK
Sbjct: 1203 EELQRQK 1209
Score = 61.6 bits (148), Expect = 6e-10
Identities = 42/202 (20%), Positives = 104/202 (51%), Gaps = 4/202 (1%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+EE + +++ E++ +E+EE +E + EEE+ + +L + + E+ + + K
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
R+ + +E + +++ ++L+ +E ++R +R +++R+ +RE RL
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLE 611
Query: 123 EEKARREEEDAKRRAEDDLKKKKALSS--MGANYSSYLAKADQKRGKKQTAREMKKKILA 180
+E+ R E+ KR ++ ++++ L S L + Q+R +++ RE +++ L
Sbjct: 612 QEE--RREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLE 669
Query: 181 ERRKPLNIDHLGEDKLRDKAKE 202
+R K + + E +L ++ +E
Sbjct: 670 QRLKREHEEERREQELAEEEQE 691
Score = 60.8 bits (146), Expect = 1e-09
Identities = 54/242 (22%), Positives = 117/242 (48%), Gaps = 15/242 (6%)
Query: 5 EVEQVEEQYEEEEEAQEEEEVQEDTAEEDA-EEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
E E+ + EEEE+ Q E Q+ EED +E++ R + + + + ++ +K+R
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR 885
Query: 64 QNKDLME--LQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 121
++ + LQ + + ++EEEEL +ER ++RR E+ Q R + ++E + L
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEEL-QREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 122 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 181
EE+ +R ++ +R+ D K ++ + L + +KR + +E +KK E
Sbjct: 945 REEREKRRRQERERQYRKDKKLQQKEEQL-------LGEEPEKRRR----QEREKKYREE 993
Query: 182 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKH 241
+ L ++ + ++ WE ++ + + + E+L R++ + L+ R Q ++
Sbjct: 994 EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Query: 242 SK 243
+
Sbjct: 1054 EE 1055
Score = 59.7 bits (143), Expect = 2e-09
Identities = 47/209 (22%), Positives = 104/209 (49%), Gaps = 14/209 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
DEE+ + ++++E EE + EEE + + EE +L ++ E + ++ Q++
Sbjct: 170 DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 63 RQNKDLMELQALIDSHFEAR----KKEEEELV--------ALKERIEK-RRAERAEQQRI 109
R+ + Q + + R +KEEE+L L+E E+ R+ ER E +R
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 110 RAEKERERQNRLAEEKARREEEDAKRRAEDDLK-KKKALSSMGANYSSYLAKADQKRGKK 168
R E+E+++Q E++ RR++E+ +R +++ + +++ L + ++R ++
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 169 QTAREMKKKILAERRKPLNIDHLGEDKLR 197
Q RE +++ ++ + + E +LR
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLR 378
Score = 59.3 bits (142), Expect = 3e-09
Identities = 49/226 (21%), Positives = 112/226 (49%), Gaps = 13/226 (5%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E EQ EQ E+ + E+E + D + + E E+ + ++ ++ + + K
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE-RERQNRL 121
+ ++ E Q + ++E E +R++++ E QQR+R+E++ R Q
Sbjct: 491 LEEEERREQQERREQQLRREQEERRE-----QRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 122 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 181
E+ +REEE +R E + ++++ L L K +++R +++ RE +++ L +
Sbjct: 546 REQLLKREEE---KRLEQE-RREQRLKREQEERRDQLLKREEERRQQRLKREQEER-LEQ 600
Query: 182 RRKPLNIDHLGEDKLRDK--AKELWETLHQLEIDKFEFGEKLKRQK 225
R K ++ L +++ R++ +E E + ++ K E E+ ++Q+
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646
Score = 58.5 bits (140), Expect = 5e-09
Identities = 53/253 (20%), Positives = 120/253 (47%), Gaps = 19/253 (7%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
E+ E+ + EEE + E+E ++ + D EEE+ L + E+ + + Q +R
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 64 QNKDLME-----------LQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRA 111
+ ++ E LQ + S + R+++EE L +R E++R E+ +QR++
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 112 EKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA 171
E+E R L E+ RR++ KR E+ L+++ L + +Q+ +++
Sbjct: 570 EQEERRDQLLKREEERRQQR-LKREQEERLEQR--LKREEVERLEQEERREQRLKREEPE 626
Query: 172 REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTL 231
E ++++L + + + +LR + +E E + E ++ ++LKR+ +
Sbjct: 627 EERRQQLLKSEEQ----EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682
Query: 232 RSRIDQAQKHSKK 244
+ ++ Q+ +++
Sbjct: 683 QELAEEEQEQARE 695
Score = 58.2 bits (139), Expect = 7e-09
Identities = 55/265 (20%), Positives = 130/265 (49%), Gaps = 25/265 (9%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEE----DAEEEKPRPKLTA---PKIPEGEKVDF 56
E +Q++E+ + +E QE QE ++ EEE+ R + T P + E + +
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Query: 57 DDIQKKRQNKDLMELQALIDSHFEARKKEEEEL-----VALKERIEKRRAERAEQQRIRA 111
+Q++ + E + E + +EEE+L L+E EKRR + E+Q +
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Query: 112 EKERERQNRL---AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKK 168
+K ++++ +L EK RR+E + K R E++L++++ + +++ KK
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Query: 169 QTAREMKKKILAERRKPLNI-----DHLGEDKLRDKAKELW----ETLHQLEIDKFEFGE 219
++ ++++L E R+ + + E++L+ + ++L ET + E+++ ++ +
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER-QYRK 1082
Query: 220 KLKRQKYDITTLRSRIDQAQKHSKK 244
+ + Q+ + LR ++ ++ ++
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERE 1107
Score = 57.8 bits (138), Expect = 9e-09
Identities = 50/240 (20%), Positives = 119/240 (49%), Gaps = 15/240 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+EE + +E+ E++E +E++E + + +EE+ +L E E+ + ++
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR----EQEEERREQQLRR 366
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE--RERQNR 120
Q ++ E Q + ++ E +E+ +R + +Q++R E++ RE+Q R
Sbjct: 367 EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
+E+ R E++ + R E LK+++ + +Q+R K+Q R+ +++
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE--- 483
Query: 181 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
R + L ++ E++ R++ + + L + + ++ E ++LKRQ+ + L+ R+ Q+
Sbjct: 484 RRERWLKLE---EEERREQQERREQQLRREQEERRE--QRLKRQEEE-ERLQQRLRSEQQ 537
Score = 57.4 bits (137), Expect = 1e-08
Identities = 50/244 (20%), Positives = 120/244 (49%), Gaps = 21/244 (8%)
Query: 7 EQVEEQYEEEEEAQEEEE-VQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 65
++ E QY EEE+ Q+EEE + + E+ +E+ R K+ + E+ + +KR+
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 66 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERERQNRLAEE 124
++ + + E + ++EE L+E EKRR + E+Q R + E ++E + L EE
Sbjct: 984 QEREK------KYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREE 1037
Query: 125 KARR--EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 182
+ +R +E + + R E++L++++ L + + R +++ R+ +K+ ++
Sbjct: 1038 REKRRLQERERQYREEEELQQEE---------EQLLGEERETRRRQELERQYRKEEELQQ 1088
Query: 183 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEF--GEKLKRQKYDITTLRSRIDQAQK 240
+ + E + R + + +L+ ++ + E+ KR++ ++ ++ Q+
Sbjct: 1089 EEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Query: 241 HSKK 244
++
Sbjct: 1149 EEEQ 1152
Score = 56.2 bits (134), Expect = 3e-08
Identities = 51/207 (24%), Positives = 96/207 (46%), Gaps = 19/207 (9%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
++ E QY +++E Q+EEE E E EK R + + E E++ ++ Q + +
Sbjct: 1014 QEWERQYRKKDELQQEEE---QLLRE--EREKRRLQERERQYREEEELQQEEEQLLGEER 1068
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAE-----------KER 115
+ Q L + + + ++EE L+E EKRR + E+Q E +ER
Sbjct: 1069 ETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER 1128
Query: 116 ERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMK 175
E++ R E+ REEE+ ++ E L+++ Y + + ++ ++Q RE +
Sbjct: 1129 EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQ 1188
Query: 176 KKILAERRKPLNIDHLGEDKLRDKAKE 202
+K ER + + E+ R K K+
Sbjct: 1189 EKRRQERERQYREE---EELQRQKRKQ 1212
Score = 55.8 bits (133), Expect = 4e-08
Identities = 62/275 (22%), Positives = 125/275 (45%), Gaps = 32/275 (11%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEV--QEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
EE Q+ Q E++ + + +E+ ++ EE++ R + K E E+ ++
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ---QLRRQ 1703
Query: 62 KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER----AEQQRIRAEKERER 117
+R+ K L E Q L E + +EEE+L E+ + RR ER E++++R E+E ++
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ 1763
Query: 118 QNR-------LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGK--- 167
R EE+ R+E E+ + R+++ +K + + + Q+ GK
Sbjct: 1764 LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRW 1823
Query: 168 ---KQTAREMKKKILAERRKPLNIDH--LGEDKLRDKAKELWETLHQLEIDKFEFGEKLK 222
+ E ++++ ER + + ++K R + +ELW+ Q + E KL+
Sbjct: 1824 EEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERE--RKLR 1881
Query: 223 RQKYDITTLRSRIDQAQKHSKKAGTPA-KGKVGGR 256
+ +R + + Q+H + + +GK GR
Sbjct: 1882 EEH-----IRRQQKEEQRHRQVGEIKSQEGKGHGR 1911
Score = 55.5 bits (132), Expect = 5e-08
Identities = 47/206 (22%), Positives = 102/206 (49%), Gaps = 13/206 (6%)
Query: 10 EEQYEEEEEA----QEEEEVQEDTAEEDAEE--EKPRPKLTA-PKIPEGEKVDFDDIQKK 62
E Q++EEE A QEEE+ ++ T + AEE E+ R +L+A P + E + +++
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
++ + + + + R++ E+EL L+E + +R ERA+Q + + +E Q R
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 123 EEKARREE------EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKK 176
++ RR++ E+ ++R L K AL L + +++ +++ + ++
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 177 KILAERRKPLNIDHLGEDKLRDKAKE 202
+ + R+ + E LR++ ++
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREK 950
Score = 54.7 bits (130), Expect = 8e-08
Identities = 56/238 (23%), Positives = 113/238 (47%), Gaps = 28/238 (11%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEED------------AEEEKPRPKLTAPKIPE 50
+E+++Q EEQ EE + + +E +D E EK R + K E
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 51 GEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRR-AERAEQQRI 109
E++ ++ Q R+ ++ Q + + + ++EE L+E EKRR ER Q R
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052
Query: 110 RAEKERERQNRLAEEK--ARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGK 167
E ++E + L EE+ RR+E + + R E++L++++ L + +KR +
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE---------EQLLREEPEKRRR 1103
Query: 168 KQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 225
++ R+ +++ E + L E++ + + +EL E ++ E + + E+L R++
Sbjct: 1104 QERERQCREE---EELQQEEEQLLREEREKRRRQEL-ERQYREEEEVQQEEEQLLREE 1157
Score = 53.5 bits (127), Expect = 2e-07
Identities = 44/203 (21%), Positives = 101/203 (49%), Gaps = 15/203 (7%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
+ +EE E E+ E+ ++E + +E+ + EE+ R + + E E+ D
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD-- 963
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
KK Q K+ + L+ E R+++E E K+ E+ ++ E+Q +R +ERE++ R
Sbjct: 964 KKLQQKE----EQLLGEEPEKRRRQERE----KKYREEEELQQEEEQLLR--EEREKRRR 1013
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
E+ R++++ ++ E L++++ + Y + + ++ ++Q E ++
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERE---T 1070
Query: 181 ERRKPLNIDHLGEDKLRDKAKEL 203
RR+ L + E++L+ + ++L
Sbjct: 1071 RRRQELERQYRKEEELQQEEEQL 1093
Score = 52.8 bits (125), Expect = 3e-07
Identities = 67/268 (25%), Positives = 115/268 (42%), Gaps = 54/268 (20%)
Query: 3 DEEVEQVEEQY----------EEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGE 52
+EE++Q EEQ E E + +EEEE+Q ++ +E R L PE E
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Query: 53 KVDFDD-------------------IQKKRQNKDLMEL---QALIDSHFEARK------- 83
D+ ++ ++ +DL L Q D E R+
Sbjct: 1233 NAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRH 1292
Query: 84 -KEEEELVALKERIEKRRAERA--EQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDD 140
EEE+L +++ KRR ++ E+Q +R E+E +R+ + + K R EE+ + R E
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 141 LKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKA 200
L++++ + Q++G+K E + + RK L E +LR +
Sbjct: 1353 LRRQERDRKFREEELRH-----QEQGRKFLEEEQRLRRQERERKFLK----EEQQLRCQE 1403
Query: 201 KELWETLHQLEIDKF-EFGEKLKRQKYD 227
+E + L Q KF E ++L RQ+ D
Sbjct: 1404 RE--QQLRQDRDRKFREEEQQLSRQERD 1429
Score = 52.8 bits (125), Expect = 3e-07
Identities = 57/260 (21%), Positives = 117/260 (45%), Gaps = 39/260 (15%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEK---PRPKLTAPKIPEGEKVDFDDIQ 60
EE +QV Q E + +EE++++++ + EEE+ R + + K ++ Q
Sbjct: 1434 EEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQ 1493
Query: 61 KKRQNKD-----------------LMELQALIDSHFEARKKEEEELVALKERIEKRRAER 103
+RQ +D L E Q L + + +EE+ + +ER ++RR +R
Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Query: 104 ----AEQQRIRAEK--------ERERQNRLAEEKARREEEDAK-RRAEDDLKKKKALSSM 150
E++++R E+ ER+R+ RL E+K RR+E++ K E L++++ +
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 151 GANYSSYLAKAD---QKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETL 207
+ + Q+R ++Q R+ + + E L + D+ ++ E
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEE 1673
Query: 208 HQLEIDKFEFGEKLKRQKYD 227
L+ + ++L+RQ+ D
Sbjct: 1674 QLLQEGE---EQQLRRQERD 1690
Score = 52.0 bits (123), Expect = 5e-07
Identities = 42/212 (19%), Positives = 100/212 (47%), Gaps = 17/212 (8%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAE----------EEKPRPKLTAPKIPEGEK 53
EE +++E++ E+ +E+EE ++ + + E EE+ +L ++ E+
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 54 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 113
+ + + KR+ + Q L+ S + +++++ +ER E+R E++R+
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 114 ERE-RQNRLAEEKARREEEDAKRRAEDDLKK--KKALSSMGANYSSYLAKADQKRGKKQT 170
+RE + R +E A E+E A+ R + + K + S A S ++ ++ G+++
Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Query: 171 AREMKKKILAERRKPLNIDHLGEDKLRDKAKE 202
+ +K+ RR+ + E++ + +E
Sbjct: 733 QEQEEKR----RRRESELQWQEEERAHRQQQE 760
Score = 50.4 bits (119), Expect = 1e-06
Identities = 61/247 (24%), Positives = 111/247 (44%), Gaps = 40/247 (16%)
Query: 14 EEEEEAQEEEEVQEDTAEEDA----EEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 69
EEE+ QE EE Q E D EE+K R + E E+ +D Q+ R+ +
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ-------EQERKFMEDEQQLRRQEGQQ 1611
Query: 70 ELQALIDSHFEARKKEEEELVALKERIEKRRAER-----AEQQRIRAEKERERQNRLAEE 124
+L+ D F +E+E+L+ +E + R ER E+ ++R + ERE+Q R +
Sbjct: 1612 QLRQERDRKF----REDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQ-EREQQLRHDRD 1666
Query: 125 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE--- 181
+ REEE + E+ +++ L + +++R Q ++++++ L
Sbjct: 1667 RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFR 1726
Query: 182 --------------RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYD 227
RR+ L E++LR + +E + L + E D+ E+ RQ+ +
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE--QQLRRQERDRKFREEEQLRQERE 1784
Query: 228 ITTLRSR 234
LRS+
Sbjct: 1785 EQQLRSQ 1791
Score = 49.7 bits (117), Expect = 3e-06
Identities = 57/263 (21%), Positives = 124/263 (47%), Gaps = 36/263 (13%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEV---QEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDI 59
++ +++ EE+ E+ + E E +++ AEE+ E+ + R K PK + + D
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715
Query: 60 QKKRQNKD-LMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQR-----IRAEK 113
Q K ++ E Q E R++ E EL +E R+ + EQ+R +AE+
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEE 775
Query: 114 ERER-QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAR 172
+ ER + RL+ RE+ + + RAE+ ++++ +L + ++K +++ R
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAEERQQREQ----------RFLPEEEEKEQRRRQRR 825
Query: 173 EMKKKI--------LAERRKPLNI----DHLGEDKLRDKAKELWETLHQLEIDKFEFGEK 220
E +K++ L R + + D L ED+ R +++E + + +++ E+
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE----QRRDQKWRWQLEEE 881
Query: 221 LKRQKYDITTLRSRIDQAQKHSK 243
KR+++ + + +Q +K +
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQ 904
Score = 48.9 bits (115), Expect = 4e-06
Identities = 54/266 (20%), Positives = 118/266 (44%), Gaps = 41/266 (15%)
Query: 3 DEEVEQVEEQYEEE-EEAQEEEEVQEDTAEEDAEEEKPR-PK----------------LT 44
+EE E++E++ + E EE + E+E+ E+ E+ E K R PK +
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 45 APKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKE-----------EEELVALK 93
P+ EG++ + +K+R+ + ++ Q +H + +++E EE+ +
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 94 ERIEKR-----------RAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLK 142
+R+ R RAE +Q+ R E E + + ++ RE+E E+ L+
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 143 KKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKE 202
+++ + +++R ++Q + + L E RK + L+++ ++
Sbjct: 842 RRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Query: 203 LWETLHQLEID-KFEFGEKLKRQKYD 227
+ L + E + + E EK +RQ+ +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQE 927
Score = 48.5 bits (114), Expect = 6e-06
Identities = 42/212 (19%), Positives = 93/212 (43%), Gaps = 17/212 (8%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
EE + +E+ E+ + + +EE+ E EE+ + E +F D ++ R
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 64 QNKDLMELQALIDSHFEARKKEEEELVALKE------------RIEKRRAERAEQQRIRA 111
+ ++L+EL+ + +++E ++ V +E R E+ + + E QR R
Sbjct: 212 R-RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 112 EKERERQNRLAE----EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGK 167
+E E Q R E + R+EEE ++R + + ++ + ++R +
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Query: 168 KQTAREMKKKILAERRKPLNIDHLGEDKLRDK 199
++ RE + + E R+ + E++ R++
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEERREQ 362
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/241 (21%), Positives = 110/241 (45%), Gaps = 26/241 (10%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKP--RPKLTAPKIPEGEKVDFDDIQK 61
E EQ + E + + +EEE ++ + EEE+ R + + E +++ + ++
Sbjct: 1347 EREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406
Query: 62 K-RQNKDLM---ELQALIDSHFEARKKEEEELVALKERIEK-----------RRAERAEQ 106
+ RQ++D E Q L + + +EEE+ V +ER K R + E+
Sbjct: 1407 QLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Query: 107 QRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRG 166
+++ E+E ++ +R ++ EEE RR E D K ++ +L +
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE------ 1520
Query: 167 KKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKY 226
++Q R+ +++ + + L G+ + +D+ ++ E QL ++ E ++L RQ+
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE-EQLRQEREE--QQLSRQER 1577
Query: 227 D 227
D
Sbjct: 1578 D 1578
Score = 41.6 bits (96), Expect = 7e-04
Identities = 35/198 (17%), Positives = 89/198 (44%), Gaps = 22/198 (11%)
Query: 16 EEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALI 75
++ QEE++ + + + EEE + + + E E + ++ +K++ + +
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD----- 165
Query: 76 DSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARR------- 128
R++ +EEL ++ ++R RAE++++++ K E + EE+ RR
Sbjct: 166 ------RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELR 219
Query: 129 ----EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 184
EE+ +RR D ++ + L K ++K +++ R+ + + E+ +
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 185 PLNIDHLGEDKLRDKAKE 202
L L ++ ++ ++
Sbjct: 280 KLERQELRRERQEEEQQQ 297
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 68.6 bits (166), Expect = 5e-12
Identities = 57/250 (22%), Positives = 128/250 (51%), Gaps = 19/250 (7%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + EE E+EE + E++E E++ E+ + KI E EK + +
Sbjct: 329 EEKMRRQEEMMWEKEE--KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 386
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEKERERQN 119
RQ + + E + I E +++EE++ +E++ E+ E+ E+ R + EK RE++
Sbjct: 387 RQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEK 446
Query: 120 RLAEEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 178
++ E++ + RE+E+ + E+ + +++ M + + ++ R +++ RE +KKI
Sbjct: 447 KIREQEEKIREQEEMMQEQEEKMGEQE--GKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504
Query: 179 LAERRKPLNIDHLGEDKLRDKAKELWETLHQL---EIDKFEFGEKLKRQKYDI----TTL 231
+ K E+ ++++ +++WE ++ E E EK++RQ+ + L
Sbjct: 505 REQEEKIRE----QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560
Query: 232 RSRIDQAQKH 241
R + ++ Q+H
Sbjct: 561 RQQEEKMQEH 570
Score = 63.9 bits (154), Expect = 1e-10
Identities = 54/241 (22%), Positives = 118/241 (48%), Gaps = 23/241 (9%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
+Q E+ + +EE+ QE EE ++ E+ E+E+ K+ E++ ++ +K R+ +
Sbjct: 285 QQEEKMWRQEEKIQEREEKIQEQEEKIREQEE--------KMRRQEEMMWEKEEKMRRQE 336
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR---LAE 123
++M + E + +E EE + +E+I ++ +R E+++IR +++R+ Q E
Sbjct: 337 EMMWEK-------EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 124 EKARREEEDAKRR----AEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 179
EK R +EE + + E + K + M + ++ R +++ RE +KKI
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIR 449
Query: 180 AERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 239
+ K + + +++ +K E + + E E EK++RQ+ I +I + +
Sbjct: 450 EQEEKIREQEEMMQEQ-EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Query: 240 K 240
+
Sbjct: 509 E 509
Score = 53.1 bits (126), Expect = 2e-07
Identities = 53/263 (20%), Positives = 135/263 (51%), Gaps = 34/263 (12%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
++DEE+++ + +E+ + E E+ + ++ + + R KL P+ + + + D +
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 259
Query: 61 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERE 116
K+ Q+ +LQA ++ + +++EE++ +E+I++R + EQ+ +IR ++E+
Sbjct: 260 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKM 318
Query: 117 RQNRLAEEKARREEEDAKRRAEDDL-KKKKALSSM--GANYSSYLAKADQKRGKKQTARE 173
R+ +E+ E+E+ RR E+ + +K++ + + + + + ++KR +++ RE
Sbjct: 319 RR----QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
Query: 174 MKK-------------KILAERRKPLNIDHL---GEDKLRDKAKELWETLHQLEIDKFEF 217
+K KI + K + + E+K+ ++ +++WE +++ E
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ----EQ 430
Query: 218 GEKLKRQKYDITTLRSRIDQAQK 240
EK++RQ+ I +I + ++
Sbjct: 431 EEKMRRQEEKIREQEKKIREQEE 453
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 68.2 bits (165), Expect = 7e-12
Identities = 59/260 (22%), Positives = 125/260 (48%), Gaps = 28/260 (10%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQED------TAEEDAEEEKPRPKLTAPKIPEGEKVDF 56
++E+ + E++ E++E +E+EE ++ EE E++ + ++ E EK
Sbjct: 327 EKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 386
Query: 57 DDIQKKRQNKDLMELQALIDSHFEARKKEEEEL--VALKERIEKRRAERAEQQRIRAEKE 114
+ QK R ++ M Q E R +E+E++ K R EK+ E+ ++ R + EK
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446
Query: 115 RERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 174
+E + EK REEE+ R E+ ++K++ + + ++K ++Q E
Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQE----------ENMWEQEEKEWQQQRLPEQ 496
Query: 175 KKKILAERRKPLNIDHL--GEDKLRD------KAKELW--ETLHQLEIDKFEFGEKLKRQ 224
K+K+ + + + + E+K+RD + K++W E + + E +E EK++ Q
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQ 556
Query: 225 KYDITTLRSRIDQAQKHSKK 244
+ + R+++ + +K
Sbjct: 557 EQKMWDQEERMEKKTQEQEK 576
Score = 64.3 bits (155), Expect = 1e-10
Identities = 47/228 (20%), Positives = 123/228 (53%), Gaps = 9/228 (3%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
M D+E + +++ E++ QE+E+ D E+ EEE+ R + K+ E E++ + +
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER--EKKMREEEEMMREQEE 610
Query: 61 KKRQNKDLM-ELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN 119
K ++ ++ M E + + E +++EE++ +E++ ++ + EQQR+ +KE+ ++
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Query: 120 RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKIL 179
+E+ + +E++ K ++ ++KK + + + R +++ RE +++++
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMRE-EEEMM 729
Query: 180 AERRKPLNIDHLGEDKLRDKAKELWETLHQL--EIDKFEFGEKLKRQK 225
E+ + + E+K++++ +E+WE ++ + +K ++L QK
Sbjct: 730 REQEEKMQEQ---EEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Score = 63.5 bits (153), Expect = 2e-10
Identities = 45/203 (22%), Positives = 105/203 (51%), Gaps = 13/203 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E + + EE+ +E+EE +E+E + EE +E++ + K+ E E+ ++ +
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLP 661
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
Q + L E + + + + + +E+EE + +E++EK+ E+ E++ EK RE ++
Sbjct: 662 EQKEKLWEHEKMQE---QEKMQEQEEKIWEQEKMEKKTQEQ-EKKTWDQEKMREEESMRE 717
Query: 123 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 182
EK REEE+ R E+ +++++ + ++ +++ E ++K+ ++
Sbjct: 718 REKKMREEEEMMREQEEKMQEQE---------EKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 183 RKPLNIDHLGEDKLRDKAKELWE 205
R P + L E + + +++WE
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWE 791
Score = 61.2 bits (147), Expect = 8e-10
Identities = 46/241 (19%), Positives = 123/241 (51%), Gaps = 19/241 (7%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
+Q E +E++E +E+EE + + + EK R + K+ E EK D +K ++ +
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREE---KKMQEQEKKTRDQEEKMQEEE 450
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER-ERQNRLAEEK 125
+ E + + E +++EE++ +E + ++ + +QQR+ +KE+ Q ++ E++
Sbjct: 451 RIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 510
Query: 126 ARREEEDAKRRAEDDL--KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 183
+ E++ K R ++++ ++KK + + ++ R ++ E ++K+ + +
Sbjct: 511 EKIWEQEEKIRDQEEMWGQEKK------------MWRQEKMREQEDQMWEQEEKMRDQEQ 558
Query: 184 KPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSK 243
K + + E K +++ K+ W+ ++ ++ E+ K+ + + +R + ++ Q+ +
Sbjct: 559 KMWDQEERMEKKTQEQEKKTWDQEEKMR-EEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 244 K 244
K
Sbjct: 618 K 618
Score = 60.8 bits (146), Expect = 1e-09
Identities = 47/245 (19%), Positives = 124/245 (50%), Gaps = 8/245 (3%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + E++ E+E+ E+E + +E E+E+ + + EK+ + +
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMW 372
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRI--RAEKERERQNR 120
RQ + L E + + + + +EE + ER+ ++ EQ+++ + EK RE +
Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
+EK R++E+ K + E+ +++++ M + + ++ + +++ E ++K
Sbjct: 433 QEQEKKTRDQEE-KMQEEERIRERE--KKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 489
Query: 181 ERRKPLNIDHLGE-DKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 239
++R P + L E +K++++ +++WE ++ + +G++ K + + +R + DQ
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE--KMREQEDQMW 547
Query: 240 KHSKK 244
+ +K
Sbjct: 548 EQEEK 552
Score = 58.5 bits (140), Expect = 5e-09
Identities = 46/228 (20%), Positives = 113/228 (49%), Gaps = 10/228 (4%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
E++++ E+ E+EE+ E+E++++ T E++ + + E EK ++ + R
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 64 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 123
+ ++ M+ Q E +++EEE+ +E++ ++ + EQQR+ +KE+ ++ +
Sbjct: 731 EQEEKMQEQE------EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 784
Query: 124 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 183
E+ + E++ K R +++ K + M + ++ G+++ ++K+ +
Sbjct: 785 EQEKIWEQEEKMRDQEE-KMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEE 843
Query: 184 KPLNIDHLGEDKLR---DKAKELWETLHQLEIDKFEFGEKLKRQKYDI 228
K + E+K++ +K +E E + E E EK++ Q+ I
Sbjct: 844 KMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
Score = 58.2 bits (139), Expect = 7e-09
Identities = 53/249 (21%), Positives = 128/249 (51%), Gaps = 17/249 (6%)
Query: 1 MSDEEV--EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDD 58
M +E+ EQ ++ ++EE+ QEEE ++E + EEE R + K+ + E+ ++
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQ--EEKMQKQEENMWEQ 483
Query: 59 IQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRI-RAEKERER 117
+K+ Q + L E + + E +++EE++ +E+I + +++++ R EK RE+
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQ-EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 118 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 177
++++ E++ + +++ K +++ +KK + ++K +++ RE +KK
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ-----EEKMREEERMREREKK 597
Query: 178 ILAER---RKPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDITTL 231
+ E R+ E+K++++ +++W E + + E +E EK+ Q+ +
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 232 RSRIDQAQK 240
+ +Q +K
Sbjct: 658 QRLPEQKEK 666
Score = 57.4 bits (137), Expect = 1e-08
Identities = 46/242 (19%), Positives = 119/242 (49%), Gaps = 29/242 (11%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
++++ + E+ E+E++ E+EE D ++ ++E+ K K E EK +D +K
Sbjct: 530 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEK----KTQEQEKKTWDQEEKM 585
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
R+ + + E + + E +++EE++ +E+++++ + EQ+ EK +E++ ++
Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE----EKMQEQEEKMW 641
Query: 123 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 182
E++ + E++ K + L ++K +K +++ +E ++KI +
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKE-----------KLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 183 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 242
+ E K +++ K+ W+ E + EK R++ ++ +R + ++ Q+
Sbjct: 691 KM--------EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM--MREQEEKMQEQE 740
Query: 243 KK 244
+K
Sbjct: 741 EK 742
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/212 (23%), Positives = 108/212 (50%), Gaps = 16/212 (7%)
Query: 3 DEEVEQVEEQYEEEEEA--QEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
+EE+ + E++ ++EE ++EE ++E + +EEK + ++ E EK + +
Sbjct: 278 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ--EKRLREQEKELREQEK 335
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEKERER 117
+ R+ K+L E + + E ++EE++ +E++ E+R E+ +Q R + +K R++
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 118 QNRLAEEKAR-REEEDAKRRAE---DDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 173
+ R+ E+ R RE+E+ R E + ++K + M ++K +++ RE
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM-QEQEKKTRDQEEKMQEEERIRE 454
Query: 174 MKKKILAERRKPLNIDHLGEDKLRDKAKELWE 205
+KK+ E E+K++ + + +WE
Sbjct: 455 REKKMREEEETMRE----QEEKMQKQEENMWE 482
Score = 56.6 bits (135), Expect = 2e-08
Identities = 51/221 (23%), Positives = 109/221 (49%), Gaps = 17/221 (7%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
EQ E+ + E E+ QE+E++QE EE E++ K K E EK +D +K R+ +
Sbjct: 662 EQKEKLW-EHEKMQEQEKMQEQ--EEKIWEQEKMEK----KTQEQEKKTWDQ-EKMREEE 713
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERE--RQNRLAEE 124
+ E + + E +++EE++ +E+++++ E EQ+ E+E + Q RL E+
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 125 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRK 184
K + E + + E ++++ M + ++ RG+++ R ++K+ + K
Sbjct: 774 KEKLWEHEKMQEQEKIWEQEE---KMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Query: 185 PLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 225
E+K+ + +++W ++E EK++ Q+
Sbjct: 831 MWG----QEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE 867
Score = 53.9 bits (128), Expect = 1e-07
Identities = 53/268 (19%), Positives = 117/268 (43%), Gaps = 40/268 (14%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E + + E++ EEEE E+ ++ +E+ E+ + ++PE ++ ++ + +
Sbjct: 449 EERIREREKKMREEEETM-REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 63 RQNKDLMELQALI-----------------------DSHFEARKK---EEEELVALKERI 96
Q + + E + I D +E +K +E+++ +ER+
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 97 EKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSS 156
EK+ E+ ++ + EK RE + EK REEE+ R E+ +++++ M
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE--EKMQEQEEK 625
Query: 157 YLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFE 216
+ ++ + +++ E ++K+ + K L E K ++LWE +K +
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK-----EKLWEH------EKMQ 674
Query: 217 FGEKLKRQKYDITTLRSRIDQAQKHSKK 244
EK++ Q+ I + Q+ KK
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKK 702
Score = 49.3 bits (116), Expect = 3e-06
Identities = 49/233 (21%), Positives = 111/233 (47%), Gaps = 19/233 (8%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFD----DI 59
++ ++ E+ +E +A E + E+ +++ + P + E EK + ++
Sbjct: 193 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLP-LAESEKSEIQLNVKEL 251
Query: 60 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRAE--KERE 116
++K + + Q ++ E ++EEEL +++I K+ + +++R+R + K RE
Sbjct: 252 KRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE 311
Query: 117 RQNRL-AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE-- 173
++ ++ +EK RE+E R E +L+++K L K ++ K + E
Sbjct: 312 QEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM 371
Query: 174 -MKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 225
+++ L E+ K + E K+RD+ + +WE +L E E+++ Q+
Sbjct: 372 WRQEERLWEQEKQMREQ---EQKMRDQEERMWEQDERLR----EKEERMREQE 417
Score = 48.9 bits (115), Expect = 4e-06
Identities = 41/187 (21%), Positives = 93/187 (49%), Gaps = 6/187 (3%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
D+E + EE E E+ EEE EE +E++ + + ++ E E+ ++ +K
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764
Query: 63 RQNKDLMELQALIDSHFEARKKEE--EELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
+ + L E + + H + +++E+ E+ ++++ EK R + E+ R + EK R ++ +
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQE-EKMRGQEEKMRGQEEK 823
Query: 121 L--AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQK-RGKKQTAREMKKK 177
+ EEK +EE + E +++ + + + ++K RG+++ RE ++K
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Query: 178 ILAERRK 184
+ + K
Sbjct: 884 MRGQEEK 890
Score = 43.1 bits (100), Expect = 2e-04
Identities = 30/154 (19%), Positives = 78/154 (50%), Gaps = 9/154 (5%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTA--------PKIPEGE 52
M E+ E+++EQ E+ +E +EE QE+ E E+ + +L K+ E E
Sbjct: 728 MMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 787
Query: 53 KVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRA 111
K+ + + + Q + + + + E + +EE++ +E++ + + +++++
Sbjct: 788 KIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWG 847
Query: 112 EKERERQNRLAEEKARREEEDAKRRAEDDLKKKK 145
++E+ + +E+ RE+E+ R E+ +++++
Sbjct: 848 QEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE 881
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/162 (20%), Positives = 79/162 (48%), Gaps = 9/162 (5%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAP-----KIPEGEKVDFD 57
+E++++ EE+ +E+EE E+E + EE E++ P+ K+ E EK+
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 58 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERI--EKRRAERAEQQRIRAEKER 115
+ + + Q + + + + E + +EE++ +E++ ++ + E++ E++
Sbjct: 793 EEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKM 852
Query: 116 ERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSY 157
E + + EEK R +EE K R +++ +++ G Y
Sbjct: 853 EEKMQGQEEKMREQEE--KMRGQEEKMREQEEKMRGQEEKIY 892
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 67.4 bits (163), Expect = 1e-11
Identities = 52/244 (21%), Positives = 116/244 (47%), Gaps = 11/244 (4%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
EQ + E+EE+ E+EE + E+ E+E+ K + E+V + Q ++Q +
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEE 255
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERI--EKRRAERAEQQRIRAE--KERERQNRLA 122
+ + + + E +++EE+++ KE+ E++ E+ EQ R + E +E+E Q R
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
Query: 123 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 182
EE+ R +EE ++ E ++K+ + + ++ + Q E +K +
Sbjct: 316 EEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQM 375
Query: 183 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 242
RK E+++R + +++ + Q+ K + GE+ ++ + + + +Q +K
Sbjct: 376 RKQ-------EEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Query: 243 KKAG 246
+ G
Sbjct: 429 EHMG 432
Score = 66.2 bits (160), Expect = 3e-11
Identities = 45/197 (22%), Positives = 98/197 (49%), Gaps = 12/197 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E+V++ EEQ ++EE E+E Q EE ++K + + + E++ + Q +
Sbjct: 247 EEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMR 306
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
Q + + E + + E K+EE++ KE++ +++ + +Q+ E+E + Q +
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ-- 364
Query: 123 EEKARREEEDAKRRAEDDLKK----KKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 178
EE+ R++EE +++ E K+ +K MG + +Q R +++ E K+++
Sbjct: 365 EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQM 424
Query: 179 LAERRKPLNIDHLGEDK 195
+ +H+GE K
Sbjct: 425 RKQE------EHMGEQK 435
Score = 59.7 bits (143), Expect = 2e-09
Identities = 48/244 (19%), Positives = 116/244 (47%), Gaps = 17/244 (6%)
Query: 5 EVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGE-KVDFDDIQKKR 63
+V + E Q E+E E+E Q E E++ + + ++ E E ++ + Q
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE 210
Query: 64 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 123
Q + + + + + E +K+EE++ +E+++K+ + +Q E Q R E
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ---------EEQMRKQE 261
Query: 124 EKARREEEDAKRRAEDDLKKKKAL---SSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
E+ R +EE + + E LK+K+ G + +Q R +++ RE +++ +
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ-MR 320
Query: 181 ERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
E+ + + E+++ ++ +++WE Q+ + + GE+ ++ + +R + +Q +K
Sbjct: 321 EQEEQMGKQ---EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Query: 241 HSKK 244
++
Sbjct: 378 QEEQ 381
Score = 46.2 bits (108), Expect = 3e-05
Identities = 33/138 (23%), Positives = 71/138 (51%), Gaps = 12/138 (8%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + EEQ E+EE ++E Q +E E+K + ++ E E+ Q +
Sbjct: 309 EEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEE------QMQ 362
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
+Q + + + + + E +K+EE++ + E++ E+ EQ + E+ RE++ ++
Sbjct: 363 KQEEQVRKQEEQMRKQEEQMRKQEEQM----RKQEEQMGEQKEQMGEQKEQMREQEEQMG 418
Query: 123 EEK--ARREEEDAKRRAE 138
E+K R++EE + E
Sbjct: 419 EQKEQMRKQEEHMGEQKE 436
Score = 37.4 bits (85), Expect = 0.013
Identities = 42/246 (17%), Positives = 117/246 (47%), Gaps = 11/246 (4%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
E+++E+ E +E + E ++ + +E K + + +P+ +V + Q + Q
Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 67 DLMELQALIDSHFEARKKEEEELVALKE-RIEKRRAERAEQQRIRAEKE---RERQNRLA 122
+ E + + E + +E+E V +E ++ ++ + EQ+ E+E RE++ ++
Sbjct: 67 QVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125
Query: 123 EEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 181
E++ + RE+E R E +++++ + + Q R ++ RE + ++ +
Sbjct: 126 EQEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 183
Query: 182 RRKPLNID-HLGED--KLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQA 238
+ + +GE ++ ++ +++ E Q++ + + GE+ ++ + + + +Q
Sbjct: 184 EGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV 243
Query: 239 QKHSKK 244
QK ++
Sbjct: 244 QKQEEQ 249
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.0 bits (162), Expect = 2e-11
Identities = 58/253 (22%), Positives = 125/253 (49%), Gaps = 35/253 (13%)
Query: 3 DEEVEQVEEQYEEEEE--AQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
+E++++ EE+ +E+EE ++EE+++E + +EE K K+ E++ ++ +
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK--EEKMRRQEEMMWEKEE 424
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN- 119
K R+ +++M + E + +E EE + +E+I ++ +R E+++IR +++R+ Q
Sbjct: 425 KMRRQEEMMWEK-------EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Query: 120 ---------RLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQT 170
R EEK R +EE R+ E +++K + + ++K +++
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 537
Query: 171 AREMKKKILAERRKPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYD 227
K+KI H E+K+R + +++W E +H E E EK+ RQ+
Sbjct: 538 IWRQKEKI-----------HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK 586
Query: 228 ITTLRSRIDQAQK 240
I +I + ++
Sbjct: 587 IREQEEKIREQEE 599
Score = 65.1 bits (157), Expect = 6e-11
Identities = 61/274 (22%), Positives = 136/274 (49%), Gaps = 40/274 (14%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPK------------LTAPKIPEG 51
E++ + EE+ +EEE+ +E+E+ QE A+ +EEK R + KI E
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510
Query: 52 EKVDFDDI-----------QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERI---E 97
EK+ ++ +K R+ +++ + I E +K+EE++ +E++ E
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 98 KRRAERAEQQRIRAEKERERQNRLAEEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSS 156
++ E+ E+ + EK RE++ ++ E++ + RE+E+ + E+ + +++ M
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE--EKMCEQEEK 628
Query: 157 YLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQL---EID 213
+ ++ R +++ RE +KKI + K E+ ++++ +++WE ++ E
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEKIRE----QEEMMQEQEEKMWEQEEKMCEQEEK 684
Query: 214 KFEFGEKLKRQKYDI----TTLRSRIDQAQKHSK 243
E EK++RQ+ + LR + ++ Q+H +
Sbjct: 685 MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 57.4 bits (137), Expect = 1e-08
Identities = 50/238 (21%), Positives = 115/238 (48%), Gaps = 19/238 (7%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ ++EE+ E+E+ +E+EE ++ EEEK R E EK + +
Sbjct: 437 EEKIRELEEKMHEQEKIREQEEKRQ-------EEEKIR---------EQEKRQEQEAKMW 480
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
RQ + + E + I E ++EE++ ++ E+ + + E+ + EK RE++
Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 540
Query: 123 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 182
+++ E+E+ R+ E+ + +++ M + ++ +++ RE ++KI +
Sbjct: 541 QKEKIHEQEEKIRKQEEKMWRQE--EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 183 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
K + + +++ +K E E + + E E EK++RQ+ I +I + ++
Sbjct: 599 EKIREQEEMTQEQ-EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Score = 52.4 bits (124), Expect = 4e-07
Identities = 30/142 (21%), Positives = 78/142 (54%), Gaps = 4/142 (2%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + EE+ ++EE E+E + EE E++ + + KI E E++ + +K
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 63 -RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER---ERQ 118
Q + + E + + E +++EE++ +++I ++ + EQ+ + E+E E++
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 675
Query: 119 NRLAEEKARREEEDAKRRAEDD 140
++ E++ + +E++ K R +++
Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEE 697
Score = 51.2 bits (121), Expect = 9e-07
Identities = 32/142 (22%), Positives = 76/142 (53%), Gaps = 4/142 (2%)
Query: 3 DEEVEQVEEQY-EEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
+E+V + EE+ E+EE+ +E+EE + E E+E+ + + EK+ + +
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636
Query: 62 KRQNKDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEKERERQ 118
+RQ + + E + I E +++EE + +E++ E++ E+ E+ + + EK R ++
Sbjct: 637 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Query: 119 NRLAEEKARREEEDAKRRAEDD 140
++ E++ R +++ K + +
Sbjct: 697 EKMWEQEVRLRQQEEKMQEHQE 718
Score = 49.3 bits (116), Expect = 3e-06
Identities = 53/259 (20%), Positives = 132/259 (50%), Gaps = 42/259 (16%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
++DEE+++ + +E+ + E E+ + ++ + + R KL P+ + + + D +
Sbjct: 275 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 332
Query: 61 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERE 116
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ +IR ++E+
Sbjct: 333 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 391
Query: 117 RQNRLAEEKARREEE-----DAKRRAEDDL----------------KKKKALSSM--GAN 153
R+ EEK RR+EE + K R ++++ +K++ + + +
Sbjct: 392 REQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 154 YSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLH 208
+ + ++KR +++ RE +K+ E + + + E+K+R++ +++W E +H
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 209 QLEIDKFEFGEKLKRQKYD 227
+ E + E+ KRQ+ +
Sbjct: 509 EQE----KIREEEKRQEQE 523
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 17/126 (13%)
Query: 1 MSDEEVEQVEEQYE---EEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFD 57
M+ E+ E++ EQ E E+EE +E+E + EE KI E EK +
Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE--------------KIREQEKKIRE 652
Query: 58 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 117
+K R+ +++M+ Q E + E+EE + +E +R+ E+ +Q +R ++ E+
Sbjct: 653 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712
Query: 118 QNRLAE 123
E
Sbjct: 713 MQEHQE 718
Score = 31.6 bits (70), Expect = 0.72
Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
EQ E+ E+EE QE+EE + E+ E+E+ + + EK+ +++ ++Q +
Sbjct: 652 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 711
Query: 67 DLMELQALIDSHFEA 81
+ E Q H EA
Sbjct: 712 KMQEHQ----EHLEA 722
Score = 31.2 bits (69), Expect = 0.93
Identities = 20/90 (22%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Query: 3 DEEVEQVEEQY-EEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
+E++ + EE+ E+E++ +E+EE + E E+E+ + + EK+ + +
Sbjct: 633 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 692
Query: 62 KRQNKDLMELQALIDSHFEARKKEEEELVA 91
+RQ + + E + + E ++ +E L A
Sbjct: 693 RRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 67.0 bits (162), Expect = 2e-11
Identities = 63/272 (23%), Positives = 129/272 (47%), Gaps = 35/272 (12%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
EE E V + Y++ + EE +ED +E+ EEEKP+ + E + + + +
Sbjct: 163 EETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN--QVEVMVEEKTTESQ 220
Query: 64 QNKDLMELQALIDSHFEARKKEEEEL----VALKERIEKRRAERAEQQRIRAEKER---- 115
+ +M L+ S E +++EE E ++ E++E+ ERAE +R R E E
Sbjct: 221 EETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERI 280
Query: 116 --ERQNRLAEEKARREEED-----AKRRAEDDLKKKKALSSMGANYSSYLAKADQKRG-- 166
E+ ++A+E+AR E E+ + R E + +++ A K ++KR
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAE 340
Query: 167 KKQTAREMKKKILAERRKPLNID-HLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 225
++Q +E +K+ ER++ + E++ R +A+E + ++++ + ++L+ +K
Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE----EEKAKVEEQKRNKQLEEKK 396
Query: 226 YDITTLRSRIDQAQKHSKKAGTPAKGKVGGRW 257
+ A + +K G + K+ G+W
Sbjct: 397 H-----------AMQETKIKGEKVEQKIEGKW 417
Score = 61.6 bits (148), Expect = 6e-10
Identities = 54/242 (22%), Positives = 116/242 (47%), Gaps = 18/242 (7%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
+ + ++ E + EEE E Q +E+ E+ ++E+ + + E E++
Sbjct: 228 LKNGQISSEEPKQEEERE-QGSDEISHHEKMEEEDKERAEAERARLEAEERERI------ 280
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER--ERQ 118
K Q+K + + +A I++ +A +E E + E+R R E++R E++R E +
Sbjct: 281 KAEQDKKIADERARIEAEEKAAAQERE-----RREAEERERMREEEKRAAEERQRIKEEE 335
Query: 119 NRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKI 178
R AEE+ R +EE+ KR AE+ + K+ A A+A+++ K + + + K
Sbjct: 336 KRAAEERQRIKEEE-KRAAEERQRIKE--EEKRAAEERQRARAEEEE-KAKVEEQKRNKQ 391
Query: 179 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQA 238
L E++ + + +K+ K + W + + DK + K+ + T ++++ ++
Sbjct: 392 LEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451
Query: 239 QK 240
Q+
Sbjct: 452 QE 453
Score = 58.9 bits (141), Expect = 4e-09
Identities = 61/281 (21%), Positives = 134/281 (47%), Gaps = 43/281 (15%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEE--KPRPKLTAPKIPEGEKVDFDDI 59
++E ++ +E+ EEEEE + + E+ E EE+ + + + + G+ +
Sbjct: 180 AEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPK 239
Query: 60 QKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER---- 115
Q++ + + E+ SH E ++E++E + E+ R E E++RI+AE+++
Sbjct: 240 QEEEREQGSDEI-----SHHEKMEEEDKE----RAEAERARLEAEERERIKAEQDKKIAD 290
Query: 116 --------------ERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKA 161
ER+ R AEE+ R EE+ +RA ++ ++ K A + +
Sbjct: 291 ERARIEAEEKAAAQERERREAEERERMREEE--KRAAEERQRIKEEEKRAAEERQRIKEE 348
Query: 162 DQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRD--KAKELWETLHQLEIDKFEFGE 219
+++ +++ + ++K AE R+ + + K+ + + K+L E H ++ K + GE
Sbjct: 349 EKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIK-GE 407
Query: 220 KLKRQKYD---ITTLRSRIDQAQ-----KHSKKAGTPAKGK 252
K++ QK + + +++ D+ Q K ++ GT + K
Sbjct: 408 KVE-QKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAK 447
Score = 57.4 bits (137), Expect = 1e-08
Identities = 52/259 (20%), Positives = 115/259 (44%), Gaps = 11/259 (4%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
++ E ++E + E +A++++++ ++ A +AEE+ + + E E++ ++ +
Sbjct: 265 AEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRA 324
Query: 62 KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 121
+ + + E + + K+EE+ ++RI K +RA ++R RA E E + ++
Sbjct: 325 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI-KEEEKRAAEERQRARAEEEEKAKV 383
Query: 122 AEEKARREEEDAKRRAEDDL----KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 177
E+K ++ E+ K ++ K ++ + N Q K+ E K
Sbjct: 384 EEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTK 443
Query: 178 ILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQ 237
+ A+R K L EDK K +E+ + + + + E + +K T ++S+ +
Sbjct: 444 VQAKREK------LQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGE 497
Query: 238 AQKHSKKAGTPAKGKVGGR 256
H K + GGR
Sbjct: 498 FMTHKLKHTENTFSRPGGR 516
Score = 50.1 bits (118), Expect = 2e-06
Identities = 32/101 (31%), Positives = 60/101 (59%), Gaps = 6/101 (5%)
Query: 45 APKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERA 104
AP++ G++++ +++++R + E + L EA + EE LK++ E+RR
Sbjct: 527 APQVEAGKRLE--ELRRRRGETESEEFEKLKQKQQEAALELEE----LKKKREERRKVLE 580
Query: 105 EQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKK 145
E+++ R ++E +R+ R EEK R +EE +RRAE K++K
Sbjct: 581 EEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621
Score = 47.4 bits (111), Expect = 1e-05
Identities = 57/293 (19%), Positives = 128/293 (43%), Gaps = 52/293 (17%)
Query: 1 MSDEEVEQVEEQY----EEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPE------ 50
M +EE EE+ EE+ A+E + ++E+ E+ A EE+ R K + E
Sbjct: 317 MREEEKRAAEERQRIKEEEKRAAEERQRIKEE--EKRAAEERQRIKEEEKRAAEERQRAR 374
Query: 51 GEKVDFDDIQKKRQNKDLME--------------LQALIDSHFEARKKEEEE----LVAL 92
E+ + ++++++NK L E ++ I+ + KK +E+ V
Sbjct: 375 AEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLK 434
Query: 93 KERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA 152
K+ EK +A++++++ +K ++ + +EK ++++E K + + +KK + + +
Sbjct: 435 KQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE-PKEEVKSFMDRKKGFTEVKS 493
Query: 153 NYSSYL-----------------AKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDK 195
++ A D K + E K++ RR+ + +K
Sbjct: 494 QNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEK 553
Query: 196 LRDKAKELWETLHQLEIDKFE----FGEKLKRQKYDITTLRSRIDQAQKHSKK 244
L+ K +E L +L+ + E E+ +R+K + + R ++ ++ K+
Sbjct: 554 LKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKE 606
Score = 45.4 bits (106), Expect = 5e-05
Identities = 48/162 (29%), Positives = 79/162 (48%), Gaps = 33/162 (20%)
Query: 30 AEEDAEEEKPRPKLTAPKI--------PEGEKVDFDDIQKKRQNKDLMELQALIDSHFEA 81
A D +E + P++ A K E E +F+ +++K+Q L EL+ E
Sbjct: 517 ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELE-------EL 568
Query: 82 RKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAE--- 138
+KK EE L+E ++R+ E A++ ++R E+E+ RL EE RR E A++R +
Sbjct: 569 KKKREERRKVLEEEEQRRKQEEADR-KLREEEEK---RRLKEEIERRRAEAAEKRQKMPE 624
Query: 139 ----DDLKKKKALSSMGANY-----SSYLAKADQK-RGKKQT 170
DD K K + G++ + +L K+ QK G K T
Sbjct: 625 DGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKST 666
Score = 37.0 bits (84), Expect = 0.017
Identities = 41/199 (20%), Positives = 85/199 (42%), Gaps = 27/199 (13%)
Query: 80 EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARRE--------EE 131
E R+++ EE+ ERI +R + E++ R + R RQ RL +++ E
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEV 68
Query: 132 DAKRRAEDDLKKKKALSSM-----GANYSSYLAKADQKRGKK-QTAREMKKKI------- 178
+A+ D+ K ++ A + LA+ +++R K+ Q A E +K+
Sbjct: 69 NAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA 128
Query: 179 ---LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 235
L RR + E++ +K ++ + EI++ E K ++ ++
Sbjct: 129 SLSLPSRRMQ---NDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKK 185
Query: 236 DQAQKHSKKAGTPAKGKVG 254
+ +K ++ P +G +G
Sbjct: 186 EDKEKEEEEEEKPKRGSIG 204
Score = 32.3 bits (72), Expect = 0.42
Identities = 49/223 (21%), Positives = 87/223 (39%), Gaps = 30/223 (13%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEV---QEDTAEEDAEEEKPR----PKLTAPKIPEGEK 53
M D E + + + EE E E + + D EE+A E+ R +L + E
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 54 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 113
D ++ QN E ++ + +E + R E+RR +R Q+ + +K
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRL-QEALERQK 119
Query: 114 E--------------RERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLA 159
E R QN AE + +EE ++ R E + + SY
Sbjct: 120 EFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE-----RYEIEETETVTKSY-- 172
Query: 160 KADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKE 202
+ + R ++ +E K+K E KP +GE+++ +E
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEEEKPKR-GSIGENQVEVMVEE 214
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 64.3 bits (155), Expect = 1e-10
Identities = 49/238 (20%), Positives = 120/238 (50%), Gaps = 36/238 (15%)
Query: 3 DEEVEQVEEQYEEEEE--AQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
+E++++ EE+ +E+EE ++EE+++E + +EE K K+ E++ ++ +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK--EEKMRRQEEMMWEKEE 363
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
K R+ +++M + E +++EE + +E+I + + EQ++IR ++E+ ++
Sbjct: 364 KMRRQEEMMWEKE------EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 417
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
E+ +R+E++AK ++ ++ R +++ RE +KK+
Sbjct: 418 KIREQEKRQEQEAKMWRQE----------------------EKIREQEEKIREQEKKMWR 455
Query: 181 ERRKPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDITTLRSRI 235
+ K + + E++ R + +E+W E +H+ E + + EK+ Q+ I ++
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE-EIWRQKEKMHEQEEKIRKQEEKV 512
Score = 58.2 bits (139), Expect = 7e-09
Identities = 53/257 (20%), Positives = 126/257 (49%), Gaps = 24/257 (9%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK-- 61
E++ + EE+ +EEE+ +E+E+ QE A+ +EEK R + KI E EK + +K
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ--EEKIREQEKKMWRQEEKIH 461
Query: 62 ---------KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAE---RAEQQRI 109
KRQ ++ M Q E +++E++ +E+I K+ + + E+ R
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
Query: 110 RAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ 169
+ EK RE++ ++ ++ + E++ R E+ + +++ + + D+ +++
Sbjct: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQE----QEDKMWRQEE 577
Query: 170 TAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIT 229
RE ++K+ + K E+K +++ +++W+ ++ + + E+ ++ +
Sbjct: 578 KIREQEEKVWRQEEKIRE----QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEE 633
Query: 230 TLRSRIDQAQKHSKKAG 246
+R + + Q+ +K G
Sbjct: 634 KIREQEEMTQEQEEKMG 650
Score = 56.6 bits (135), Expect = 2e-08
Identities = 57/251 (22%), Positives = 129/251 (51%), Gaps = 28/251 (11%)
Query: 3 DEEVEQVEEQYEEEEEA--QEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
+E++ + EE+ E+EE ++EE+++E E EEEK + KI E EK + +
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQE-EMWREEEKMHEQ---EKIWEEEKRQEQEDK 571
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR 120
RQ + + E + + E +++EE+ +E++ K ++++IR ++E+ ++
Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK------QEEKIREQEEKIQEQ- 624
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
EEK R +EE K R ++++ +++ MG + ++ + +++T ++KI
Sbjct: 625 --EEKIREQEE--KIREQEEMTQEQE-EKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 181 ERRKPLNIDHL---GEDKLRDKAKELWETLHQL---EIDKFEFGEKLKRQKYDI----TT 230
+ +K + E+ ++++ +++WE ++ E E EK++RQ+ +
Sbjct: 680 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Query: 231 LRSRIDQAQKH 241
LR + ++ Q+H
Sbjct: 740 LRQQEEKMQEH 750
Score = 52.8 bits (125), Expect = 3e-07
Identities = 51/230 (22%), Positives = 112/230 (48%), Gaps = 29/230 (12%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
EQ E+ +EE E+EE E E+E+ K+ E++ ++ +K R+ +
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE--------KMRRQEEMMWEKEEKMRRQE 383
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR---LAE 123
++M + E + +E EE + +E+I ++ +R E+++IR +++R+ Q E
Sbjct: 384 EMMWEK-------EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 124 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 183
EK R +EE + + + ++++ + + + ++KR +++ ++KI +
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKI------HEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 184 --KPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDI 228
+ H E+K+R + +++W E + + E E EK+ RQ+ I
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Score = 50.8 bits (120), Expect = 1e-06
Identities = 50/251 (19%), Positives = 120/251 (47%), Gaps = 17/251 (6%)
Query: 3 DEEVEQVEEQYEEEEEA--QEEEEV--QEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDD 58
+E++ + EE+ E+E+ ++EE++ QE EE+ +E+ KI E E++
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 59 IQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 118
+ Q + + + + + E +++EE++ +E++ ++ + EQ+ + E+E+ +
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 119 NRLAEEKARREEEDAK--RRAEDDLKKKKALSSMGANYSSYLAKADQKRGK----KQTAR 172
E+ +R+E++ K R+ E ++++ + K ++ K ++ R
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR 615
Query: 173 EMKKKILAERRKPLNIDHLGEDKLRDK---AKELWETLHQLEIDKFEFGEKLKRQKYDIT 229
E ++KI + K E+K+R++ +E E + + E E EK++ Q+ +
Sbjct: 616 EQEEKIQEQEEKIRE----QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
Query: 230 TLRSRIDQAQK 240
+I + +K
Sbjct: 672 RQEEKIREQEK 682
Score = 48.1 bits (113), Expect = 7e-06
Identities = 55/250 (22%), Positives = 126/250 (50%), Gaps = 22/250 (8%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
++DEE+++ + +E+ + E E+ + ++ + + R KL P+ + + + D +
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 271
Query: 61 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERE 116
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ +IR ++E+
Sbjct: 272 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 117 RQNRLAEEKARREEE-----DAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA 171
R+ EEK RR+EE + K R ++++ +K M K ++ R +++
Sbjct: 331 REQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRQEEMM 386
Query: 172 REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGE-KLKRQKYDITT 230
E ++KI + L ++K+R++ ++ E E +K + E K+ RQ+ I
Sbjct: 387 WEKEEKI-----RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 441
Query: 231 LRSRIDQAQK 240
+I + +K
Sbjct: 442 QEEKIREQEK 451
Score = 47.4 bits (111), Expect = 1e-05
Identities = 54/248 (21%), Positives = 120/248 (48%), Gaps = 42/248 (16%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E + + EE+ +EE E+E + EE E++ K+ E++ ++ +K
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-------EKMRRQEEMMWEKEEKI 393
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER----- 117
R+ ++ M Q I E +++EEE++ ++R E+ ++++IR ++E+ R
Sbjct: 394 RELEEKMHEQEKIREQ-EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
Query: 118 ----------QNRLAEEKARREEEDAKRRAE-----DDLKKKKALSSMGANYSSYLAKAD 162
Q ++ EE+ R+E+E+ R+ E +++ ++K M + +
Sbjct: 453 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK--EKMHEQEEKIRKQEE 510
Query: 163 QKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGE 219
+ +++ RE ++KI + K E+K+R++ +E+W E +H+ E + E
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWR----QEEKIREQ-EEMWREEEKMHEQE----KIWE 561
Query: 220 KLKRQKYD 227
+ KRQ+ +
Sbjct: 562 EEKRQEQE 569
Score = 46.2 bits (108), Expect = 3e-05
Identities = 43/211 (20%), Positives = 101/211 (47%), Gaps = 34/211 (16%)
Query: 1 MSDEEVEQVEEQYEEEEEA--QEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDD 58
M ++E EE+ +E+E+ ++EE+++E + +EEK R + EK +
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR--------EQEEKRQEQE 604
Query: 59 IQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 118
+ +Q + + E + I E +++EE++ +E +++ + EQ+ E+E + Q
Sbjct: 605 EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Query: 119 NR----LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 174
+ +E+ RE+E R E+ +++++ + Q++ +K +E
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMM--------------QEQEEKMWEQEE 710
Query: 175 KKKILAERRKPLNIDHLGEDKLRDKAKELWE 205
K + E+ + + E+K+R + +++WE
Sbjct: 711 K---MCEQEEKMQEQ---EEKMRRQEEKMWE 735
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 64.3 bits (155), Expect = 1e-10
Identities = 52/252 (20%), Positives = 125/252 (49%), Gaps = 18/252 (7%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
+Q E+ + +EE+ QE+EE + + E+E+ + + EK+ + + RQ +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRAEKERERQNRLAEEK 125
+ E + I E ++EE++ E+I+++ E ++++IR ++E+ ++ +EK
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
Query: 126 ARREEEDAKRRAEDDL----KKKKALSSMGANYSSYLAKADQK--------RGKKQTARE 173
RE+++ R E+++ +K + L M + L + ++K + +++ +
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 174 MKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDI 228
++KI + K + L E+K+ ++ +++W E + + E E EK++RQ+ +
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 229 TTLRSRIDQAQK 240
R+ Q ++
Sbjct: 534 REQEVRLWQQEE 545
Score = 52.0 bits (123), Expect = 5e-07
Identities = 28/122 (22%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ +VEE+ +EEEE +E+E + EE +E++ + + + EK+ + +
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
RQ + + E + + E +++EE++ + R+ ++ E+ ++Q +R ++ ER +L
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-EKMQEQEVRLQELEERLGKLG 565
Query: 123 EE 124
++
Sbjct: 566 QK 567
Score = 50.8 bits (120), Expect = 1e-06
Identities = 35/139 (25%), Positives = 77/139 (55%), Gaps = 11/139 (7%)
Query: 3 DEEV-EQVEEQYEEEEEAQEEEEVQED------TAEEDAEEEKPRPKLTAPKIPEGEKVD 55
DE++ EQ EE + +EE+ +E EE+ +D EE +EE+ + + KI E+
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478
Query: 56 FDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER 115
+ +K + + L++ + I E ++EE++ +E+++ E+ E+ + + EK R
Sbjct: 479 QEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ----EQEEKMQRQEEKMR 534
Query: 116 ERQNRLAEEKARREEEDAK 134
E++ RL +++ + +E++ +
Sbjct: 535 EQEVRLWQQEEKMQEQEVR 553
Score = 50.4 bits (119), Expect = 1e-06
Identities = 49/221 (22%), Positives = 104/221 (47%), Gaps = 40/221 (18%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
E+ E+++EQ EEE ++EE+++E +EEK + K+ R
Sbjct: 378 EQDEKIQEQ--EEEMWRQEEKIRE-------QEEKRQEKMW------------------R 410
Query: 64 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 123
Q K + E I E ++EE++ L+E ++ + + E + E+E + Q + E
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ--E 468
Query: 124 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 183
EK +R+EE + + E +++K L + + ++K +++ +++ + E+
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQ-----EEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523
Query: 184 KPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKL 221
+ + E+K+R++ LW E + + E+ E E+L
Sbjct: 524 EKMQRQ---EEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 64.3 bits (155), Expect = 1e-10
Identities = 52/252 (20%), Positives = 125/252 (49%), Gaps = 18/252 (7%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
+Q E+ + +EE+ QE+EE + + E+E+ + + EK+ + + RQ +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAER-AEQQRIRAEKERERQNRLAEEK 125
+ E + I E ++EE++ E+I+++ E ++++IR ++E+ ++ +EK
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEK 413
Query: 126 ARREEEDAKRRAEDDL----KKKKALSSMGANYSSYLAKADQK--------RGKKQTARE 173
RE+++ R E+++ +K + L M + L + ++K + +++ +
Sbjct: 414 KMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR 473
Query: 174 MKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDI 228
++KI + K + L E+K+ ++ +++W E + + E E EK++RQ+ +
Sbjct: 474 QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKM 533
Query: 229 TTLRSRIDQAQK 240
R+ Q ++
Sbjct: 534 REQEVRLWQQEE 545
Score = 52.0 bits (123), Expect = 5e-07
Identities = 28/122 (22%), Positives = 68/122 (55%), Gaps = 1/122 (0%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ +VEE+ +EEEE +E+E + EE +E++ + + + EK+ + +
Sbjct: 447 EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMW 506
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
RQ + + E + + E +++EE++ + R+ ++ E+ ++Q +R ++ ER +L
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-EKMQEQEVRLQELEERLGKLG 565
Query: 123 EE 124
++
Sbjct: 566 QK 567
Score = 50.8 bits (120), Expect = 1e-06
Identities = 35/139 (25%), Positives = 77/139 (55%), Gaps = 11/139 (7%)
Query: 3 DEEV-EQVEEQYEEEEEAQEEEEVQED------TAEEDAEEEKPRPKLTAPKIPEGEKVD 55
DE++ EQ EE + +EE+ +E EE+ +D EE +EE+ + + KI E+
Sbjct: 419 DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478
Query: 56 FDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER 115
+ +K + + L++ + I E ++EE++ +E+++ E+ E+ + + EK R
Sbjct: 479 QEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ----EQEEKMQRQEEKMR 534
Query: 116 ERQNRLAEEKARREEEDAK 134
E++ RL +++ + +E++ +
Sbjct: 535 EQEVRLWQQEEKMQEQEVR 553
Score = 50.4 bits (119), Expect = 1e-06
Identities = 49/221 (22%), Positives = 104/221 (47%), Gaps = 40/221 (18%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
E+ E+++EQ EEE ++EE+++E +EEK + K+ R
Sbjct: 378 EQDEKIQEQ--EEEMWRQEEKIRE-------QEEKRQEKMW------------------R 410
Query: 64 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 123
Q K + E I E ++EE++ L+E ++ + + E + E+E + Q + E
Sbjct: 411 QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQ--E 468
Query: 124 EKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERR 183
EK +R+EE + + E +++K L + + ++K +++ +++ + E+
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQ-----EEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523
Query: 184 KPLNIDHLGEDKLRDKAKELW---ETLHQLEIDKFEFGEKL 221
+ + E+K+R++ LW E + + E+ E E+L
Sbjct: 524 EKMQRQ---EEKMREQEVRLWQQEEKMQEQEVRLQELEERL 561
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 63.9 bits (154), Expect = 1e-10
Identities = 69/284 (24%), Positives = 130/284 (45%), Gaps = 51/284 (17%)
Query: 6 VEQVEEQYEE-----EEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
VEQ+E+ EE E+ QE+E++ E + E+ K + K+ ++ + +
Sbjct: 262 VEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEIKRINDE 321
Query: 61 KKRQNKDLMELQALID--------------SHFEA-----RKKEEEELVALKERIEKRRA 101
++Q +L+ + L D + FEA R+++E+E+ L+ EK +
Sbjct: 322 NQKQKAELLAQEKLADQMVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQD 381
Query: 102 ERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKA 161
+AEQ +RA++ +E +R E R+E+E+A+++ E + + +K+ A LA
Sbjct: 382 YQAEQDALRAKRNQEVADR---EWRRKEKENARKKMETEAELRKSRLEQVAFKEHALAV- 437
Query: 162 DQKRGKKQTAREMKKKILAERRKPLNIDHLGEDK-----------LRDKAKELWETLHQL 210
+ Q R+ ++IL +R+ + + L E+K LR + +E + Q
Sbjct: 438 -----QVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQHANELRRQVRENQQKEVQN 492
Query: 211 EIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS----KKAGTPAK 250
I FE G +LK + R RID+ ++ + G P K
Sbjct: 493 RIATFEEGRRLKE---EAQKRRERIDEIKRKKLEELRATGLPEK 533
Score = 47.8 bits (112), Expect = 1e-05
Identities = 45/167 (26%), Positives = 79/167 (47%), Gaps = 26/167 (15%)
Query: 5 EVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAP--------KIPEGEKVDF 56
E EQ + E+E+E +QE + AE++ R K K E +
Sbjct: 355 EAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENARKKM 414
Query: 57 D---DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAE-------- 105
+ +++K R + + AL R + E L A +E+IEK R E +
Sbjct: 415 ETEAELRKSRLEQVAFKEHALAVQVQRDRDEFERILRAQREQIEKERLEEEKKATGRLQH 474
Query: 106 ----QQRIRAEKERERQNRLAE-EKARREEEDAKRRAE--DDLKKKK 145
++++R +++E QNR+A E+ RR +E+A++R E D++K+KK
Sbjct: 475 ANELRRQVRENQQKEVQNRIATFEEGRRLKEEAQKRRERIDEIKRKK 521
Score = 40.0 bits (92), Expect = 0.002
Identities = 58/269 (21%), Positives = 127/269 (47%), Gaps = 33/269 (12%)
Query: 1 MSDEEVEQVEEQYEEEEEA------------QEEEEVQEDTA-----EEDAEEEKPRPKL 43
++ EE+E ++ +++E+EA +++E V + EE A+E
Sbjct: 119 LTREELEARDQAFKKEKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQ 178
Query: 44 TAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER 103
A K+ ++ + D+ K N + A+ D+ +++ ++EL ++R+++ E
Sbjct: 179 RANKLRMEQEEELKDMSKIILNA---KCHAIRDAQILEKQQIQKELDTEEKRLDQMM-EV 234
Query: 104 AEQQRIRAEKERERQNRLAEEKARRE--EEDAKRRAEDDL--KKKKALSSMGANYSSYLA 159
Q+ I+ ++E ER+ R + RR+ E+ K + E L ++++ Y L
Sbjct: 235 ERQKSIQRQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQ 294
Query: 160 KADQKRGKKQTAREMK-----KKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDK 214
+ D K +++ +++K K+I E +K + L ++KL D+ + +
Sbjct: 295 EEDLKDMERRQQQKLKMQAEIKRINDENQKQ-KAELLAQEKLADQMVMEFTKKKMAREAE 353
Query: 215 FEF-GEKLKRQK-YDITTLRSRIDQAQKH 241
FE E+++R+K +I LR+ ++AQ +
Sbjct: 354 FEAEQERIRREKEKEIARLRAMQEKAQDY 382
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 63.5 bits (153), Expect = 2e-10
Identities = 56/245 (22%), Positives = 104/245 (42%), Gaps = 31/245 (12%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
+D E ++ + E E+ E E E E D E E+ R + D D QK
Sbjct: 228 TDRERDRQRKTEREREKQAERERASERETERDKERERERDR----------DRDRDRRQK 277
Query: 62 KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 121
+R+ + + Q + E +K E + +ER R+ ER ++ E+ERERQ
Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERER----ERERERQRET 333
Query: 122 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 181
++ + E KR+ E D ++ + + G++Q RE +++ +
Sbjct: 334 ERDREKERERKRKRQTEMDRERNRQTG---------------REGRRQAERERERERERD 378
Query: 182 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKH 241
R+ + D+ RD+ KE E + + D EK + ++ D + R R ++ ++
Sbjct: 379 RQSAREREERERDRDRDRQKER-ERQTEKDRDGQRETEKQREREKDRESERGR-ERGRER 436
Query: 242 SKKAG 246
K+ G
Sbjct: 437 EKQKG 441
Score = 54.7 bits (130), Expect = 8e-08
Identities = 47/246 (19%), Positives = 109/246 (44%), Gaps = 22/246 (8%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+++ + +++ E + +E+E ++ E D + EK R + QK+
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNR-----------------QKE 126
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
R+ + E + D + +++ E + A KER + ER Q +KERER+
Sbjct: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQ 186
Query: 123 EEKARREEEDAKRRAED---DLKKKKALSSMGANYSSYLAKADQKRGK-KQTAREMKKKI 178
E + R + + + + ED + +++ + + D++R + ++T RE +K+
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
Query: 179 LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQA 238
ER + +++ R++ ++ Q E ++ ++ +R + D T R R Q
Sbjct: 247 ERERASERETER-DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQR 305
Query: 239 QKHSKK 244
++ ++
Sbjct: 306 ERERER 311
Score = 45.1 bits (105), Expect = 6e-05
Identities = 36/179 (20%), Positives = 80/179 (44%), Gaps = 11/179 (6%)
Query: 24 EVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARK 83
+ +D +D E + + + + + E+ + D +++R+ KD + D H E ++
Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTER-ETDRKRERRREKDRHRKR---DRHRERQR 99
Query: 84 KEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKK 143
E+E +ER R +R ++ +KERER+ E+ R + D +R E ++
Sbjct: 100 DREKE----RERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERE---RQ 152
Query: 144 KKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKE 202
+ A + ++ +K+ RE ++ ER + ++ ED+ ++ +E
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Score = 42.0 bits (97), Expect = 5e-04
Identities = 28/149 (18%), Positives = 66/149 (44%), Gaps = 5/149 (3%)
Query: 10 EEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLM 69
E + E E E + + E + D +E + K + ++ + + + +++R+ +
Sbjct: 318 ERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER 377
Query: 70 ELQALIDSHFEAR-----KKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 124
+ Q+ + R +++E E K+R +R E+ ++ E ER R+ E
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 125 KARREEEDAKRRAEDDLKKKKALSSMGAN 153
K + E D +R+ + +++ S++ N
Sbjct: 438 KQKGRERDRERQTDRQAGRQRKRSTLYVN 466
Score = 40.0 bits (92), Expect = 0.002
Identities = 28/149 (18%), Positives = 75/149 (50%), Gaps = 5/149 (3%)
Query: 36 EEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKER 95
+E PR + + + D + ++K + + + Q ++ + ++ E++ ++R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 96 IEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYS 155
+R+ +R +++ + ++ER+RQ EK R +++ +R E + ++ + + G
Sbjct: 94 HRERQRDREKERERQTDRERDRQ----REKERNRQKERERETEREGERGRDRQTDGQRER 149
Query: 156 SYLAKADQKRGKKQTAREMKKKILAERRK 184
A+++R ++QT RE +++ R+K
Sbjct: 150 ERQRDAEKER-ERQTDRERQRQTERNRQK 177
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 63.2 bits (152), Expect = 2e-10
Identities = 58/224 (25%), Positives = 103/224 (45%), Gaps = 46/224 (20%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
+ E E+ +E+ E E+ +E E+ E E +E+K R K K ++
Sbjct: 30 TQRESERKKERREREKRKREREK--ERKRERGKKEKKKRKKRERGK------------ER 75
Query: 62 KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 121
+R+ K+ E ++KE E K + EK++ ER ++ R +K++ER+ R
Sbjct: 76 ERKRKER-----------EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE 124
Query: 122 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 181
E K RRE + KRR + K++ K +++RGK++ R+ +KK E
Sbjct: 125 RENKQRRERKRKKRRKKKRRKER---------------KREKERGKRERKRKKRKKEERE 169
Query: 182 RRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 225
+++ N K R K +E E + + K E +K +R+K
Sbjct: 170 KKRERN------RKERKKERERKERRERKKERKKERRKKKERKK 207
Score = 52.4 bits (124), Expect = 4e-07
Identities = 47/163 (28%), Positives = 80/163 (49%), Gaps = 23/163 (14%)
Query: 82 RKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDL 141
++K E E +ER +K + +R +++R + E+ER+R+ R + K RRE+E KR+ E
Sbjct: 45 KRKREREKERKRERGKKEKKKRKKRERGK-ERERKRKEREKQRKERREKERRKRKKE--- 100
Query: 142 KKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAK 201
KKK+ G + ++K+ K++ RE + K ER++ K R K K
Sbjct: 101 KKKRERKQRG--------RRERKKKKERKERERENKQRRERKR----------KKRRKKK 142
Query: 202 ELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKK 244
E + E K E K KR+K + R R + +K ++
Sbjct: 143 RRKERKREKERGKRERKRK-KRKKEEREKKRERNRKERKKERE 184
Score = 51.6 bits (122), Expect = 7e-07
Identities = 36/144 (25%), Positives = 73/144 (50%), Gaps = 9/144 (6%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
+E E+ ++ E++ + + E+E ++ E+ E K R + K E + +++R
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERK-------ERER 125
Query: 64 QNKDLMELQALIDSHFEARK--KEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 121
+NK E + + RK K E+E + + +KR+ E E++R R KER+++
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
Query: 122 AEEKARREEEDAKRRAEDDLKKKK 145
E + R++E +RR + + KK +
Sbjct: 186 KERRERKKERKKERRKKKERKKDR 209
Score = 36.6 bits (83), Expect = 0.022
Identities = 26/133 (19%), Positives = 60/133 (45%)
Query: 112 EKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTA 171
E ER+++ R E++ R E++ KR KKK+ G + +++R +++
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 172 REMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTL 231
K+K ++R+ K +++ + E + E + + +K +R++
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 232 RSRIDQAQKHSKK 244
R + ++ +K KK
Sbjct: 153 RGKRERKRKKRKK 165
Score = 36.2 bits (82), Expect = 0.029
Identities = 27/112 (24%), Positives = 59/112 (52%), Gaps = 6/112 (5%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
E+ + E ++ +E +E + + + + K R K K + EK + ++KR+ +
Sbjct: 105 ERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK-ERGKRERKRKKR 163
Query: 67 DLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQ 118
E + + + + RKKE E KER E+++ ER +++R + E++++R+
Sbjct: 164 KKEEREKKRERNRKERKKERER----KERRERKK-ERKKERRKKKERKKDRK 210
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 62.4 bits (150), Expect = 4e-10
Identities = 48/250 (19%), Positives = 129/250 (51%), Gaps = 17/250 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + EE+ E+E E+E + E+ E++ + ++ E +K+ + Q +
Sbjct: 254 EEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQ 313
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERI-EKRRAERAEQQRIRAEKER--ERQN 119
Q + + E + E +++EE++ +ER+ E+ + R ++Q++R ++ER E+
Sbjct: 314 EQEEKMWEQE-------EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 120 RLAEEKARREEEDAKRRAEDDLKKKKAL----SSMGANYSSYLAKADQKRGKKQTAREMK 175
RL E++ R E++ E+ +++++ + M + + ++ + +++ E +
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 176 KKILAERRKPLNIDHLGE-DKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSR 234
+K ++R P + L E +K++++ +++WE ++ + +G++ K + + +R +
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE--KMREQ 484
Query: 235 IDQAQKHSKK 244
DQ + +K
Sbjct: 485 EDQMWEQEEK 494
Score = 61.6 bits (148), Expect = 6e-10
Identities = 52/266 (19%), Positives = 132/266 (49%), Gaps = 26/266 (9%)
Query: 1 MSDEEV---EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFD 57
M D+E +Q E +E++E +E+EE + + +EEK R + K E EK +D
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREE---KKTQEQEKKTWD 551
Query: 58 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEK- 113
+K R+ + + E + + E +++EE++ +E++ E++ E+ E+ + + EK
Sbjct: 552 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611
Query: 114 --------ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKR 165
E+E ++++ E++ E++ K + +++ K + M + ++ +
Sbjct: 612 WEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE-KMWEQEEKMREQEEKMREQEEKMQ 670
Query: 166 GKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQL--EIDKFEFGEKLKR 223
G+++ RE ++K+ + K E+K+R + +++W ++ + +K E+++
Sbjct: 671 GQEEKMREQEEKMQGQEEKMRE----QEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE 726
Query: 224 QKYDITTLRSRI-DQAQKHSKKAGTP 248
++ I + ++ ++ +H ++ P
Sbjct: 727 KEERIRDQKEKMQERLPEHEERCSEP 752
Score = 60.5 bits (145), Expect = 1e-09
Identities = 49/235 (20%), Positives = 113/235 (48%), Gaps = 22/235 (9%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + E++ E+E+ E+E + ++ E+E+ + + EK+ + +
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW 334
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRI--RAEKERERQNR 120
RQ + L E + + + + +EE + ER+ ++ EQ+++ + EK +E +
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA 180
EK REEE+ R E+ ++K++ + + ++K ++Q E K+K+
Sbjct: 395 REREKKMREEEETMREQEEKMQKQE----------ENMWEQEEKEWQQQRLPEQKEKLWE 444
Query: 181 ERRKPLNIDHL--GEDKLRD------KAKELW--ETLHQLEIDKFEFGEKLKRQK 225
+ + + + E+K+RD + K++W E + + E +E EK++ Q+
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 499
Score = 56.2 bits (134), Expect = 3e-08
Identities = 46/247 (18%), Positives = 120/247 (48%), Gaps = 17/247 (6%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAE-EDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQN 65
EQ E+ +E+E+ ++EE++ E + D EE + K K+ EK+ + Q Q
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK----KMWRQEKMREQEDQMWEQE 492
Query: 66 KDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR----- 120
+ + + + + E +++E L +ER+ +++ +++++R EK+ + Q +
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Query: 121 ---LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKK 177
+ EE+ RE E R E+ +++++ M + ++ +++ +E ++K
Sbjct: 553 EEKMREEERMREREKKMREEEEMMREQE--EKMQEQEEKMREQEEKMWEQEEKMQEQEEK 610
Query: 178 ILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQ 237
+ + K + EDK++++ + +WE +++ + + E+ ++ + +R + ++
Sbjct: 611 MWEQEEKMWEQEE--EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Query: 238 AQKHSKK 244
Q +K
Sbjct: 669 MQGQEEK 675
Score = 49.7 bits (117), Expect = 3e-06
Identities = 45/247 (18%), Positives = 121/247 (48%), Gaps = 17/247 (6%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E + + E++ EEEE E+ ++ +E+ E+ + ++PE ++ ++ + +
Sbjct: 391 EERIREREKKMREEEETM-REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERI--EKRRAERAEQQRIRAEKERERQNR 120
Q + + E E + +++EE+ ++++ +++ E+ +Q + EK R+++ +
Sbjct: 450 EQEEKIWEQ--------EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 501
Query: 121 LAEEKARREEEDAK-RRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMK---K 176
+ +++ R E+D + R E+ ++++K + K Q++ KK +E K +
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE--EKKTQEQEKKTWDQEEKMREE 559
Query: 177 KILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRID 236
+ + ER K + + + +K +E E + + E +E EK++ Q+ + ++
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Query: 237 QAQKHSK 243
+ ++ K
Sbjct: 620 EQEEEDK 626
Score = 49.3 bits (116), Expect = 3e-06
Identities = 49/234 (20%), Positives = 109/234 (46%), Gaps = 21/234 (8%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKP--RPKLTAPKIPEGE-KVDFDDIQ 60
++ ++ E+ +E +A E + E+ +++ + KL + + E +++ +++
Sbjct: 155 KKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELK 214
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEK------RRAERAEQQRIRAEKE 114
+K + + Q ++ E ++EEEL +++I K R+ ER +Q + ++
Sbjct: 215 RKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQ 274
Query: 115 RERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE- 173
E+ R +EK RE+E R E +L+++K L K ++ K + E
Sbjct: 275 EEKMRR--QEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Query: 174 --MKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQK 225
+++ L E+ K + E K+RD+ + +WE +L E E+++ Q+
Sbjct: 333 MWRQEERLWEQEKQMREQ---EQKMRDQEERMWEQDERLR----EKEERMREQE 379
Score = 46.6 bits (109), Expect = 2e-05
Identities = 43/220 (19%), Positives = 107/220 (48%), Gaps = 25/220 (11%)
Query: 24 EVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARK 83
+VQ +T +E+ ++ + KI + E+ + RQ + L E + + E +
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEE------KMWRQEERLREQEGKMREQEEKMR 279
Query: 84 KEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKK 143
++E+ L ++ + ++ E EQ+++R E+E Q + EEK +EE + + E ++
Sbjct: 280 RQEKRLREQEKELREQEKELREQKKLR---EQEEQMQEQEEKMWEQEEKMREQEEKMWRQ 336
Query: 144 KKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKEL 203
++ L + Q R ++Q R+ ++++ + + E+++R++ K +
Sbjct: 337 EERL----------WEQEKQMREQEQKMRDQEERMWEQDERLRE----KEERMREQEK-M 381
Query: 204 WETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHSK 243
WE +++ ++ E+ K+ + + T+R + ++ QK +
Sbjct: 382 WEQEEKMQ-EEERIREREKKMREEEETMREQEEKMQKQEE 420
Score = 37.7 bits (86), Expect = 0.010
Identities = 40/199 (20%), Positives = 88/199 (44%), Gaps = 23/199 (11%)
Query: 62 KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRL 121
K++N +L E L +S E+ + L + KR+ ERA+ + + ++
Sbjct: 186 KKKNAELQEKLRLAES--------EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMW 237
Query: 122 AEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 181
+E+ RE+E R+ E+ + +++ L + + K +++ ++K L E
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQE----------ERLREQEGKMREQEEKMRRQEKRLRE 287
Query: 182 RRKPLNIDHLGEDKLRD--KAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQ 239
+ K L E +LR+ K +E E + + E +E EK++ Q+ + R+ + +
Sbjct: 288 QEKELREQ---EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 240 KHSKKAGTPAKGKVGGRWK 258
K ++ + + W+
Sbjct: 345 KQMREQEQKMRDQEERMWE 363
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 62.0 bits (149), Expect = 5e-10
Identities = 55/204 (26%), Positives = 103/204 (50%), Gaps = 34/204 (16%)
Query: 4 EEVEQVEEQYEE--EEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
E VEQ++E+ ++ E++ + +E E EE EEK + K A K+ E E +
Sbjct: 586 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA-------R 638
Query: 62 KRQNKDLMELQALIDSHFEAR------KKEEEELVAL------KERIEKRRAERAEQQR- 108
++Q ++ L+ L E R KK+EEE L K E+R ER EQ+R
Sbjct: 639 RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR 698
Query: 109 --------IRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAK 160
R ++ RE++ +LAE++ RRE+E + +AE +L++++ ++ +
Sbjct: 699 EQERREQERREQERREQERQLAEQERRREQE--RLQAERELQERE--KALRLQKEQLQRE 754
Query: 161 ADQKRGKKQTAREMKKKILAERRK 184
++K+ K++ R ++++ E+ K
Sbjct: 755 LEEKKKKEEQQRLAERQLQEEQEK 778
Score = 60.1 bits (144), Expect = 2e-09
Identities = 65/261 (24%), Positives = 122/261 (46%), Gaps = 35/261 (13%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEE-----DAEEEKPRPKLTAPKIPEGEKVDFDD 58
EE EQ+ Q EE++ + EEV+ E A E + K K E + D+
Sbjct: 549 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 608
Query: 59 IQKKRQNKDLMELQALIDS------HFEARKKEEEE---LVALKERIEKRRAERAEQQRI 109
+K + + L E +A + EAR+K+EEE L L++ E+RR + Q+
Sbjct: 609 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK-- 666
Query: 110 RAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ 169
+ E+E+ER + AE K E+ + +RR ++ +++ + +Q+R ++Q
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQE---------------RREQER-REQ 710
Query: 170 TAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIT 229
RE ++++ + R+ E +L+++ K L QL+ E EK K+++
Sbjct: 711 ERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ---RELEEKKKKEEQQRL 767
Query: 230 TLRSRIDQAQKHSKKAGTPAK 250
R ++ +K +K+A +K
Sbjct: 768 AERQLQEEQEKKAKEAAGASK 788
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/206 (17%), Positives = 95/206 (46%), Gaps = 17/206 (8%)
Query: 50 EGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRI 109
E E+ +++++K + + L + D R++ EE + +ER+ K R +++
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDK----RRRLEEVKLKREERLRKVLQARERVEQM 591
Query: 110 RAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSM-----------GANYSSYL 158
+ EK+++ + + A+ + E+ +R AE+ KKK A M A +L
Sbjct: 592 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 651
Query: 159 AKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFG 218
+ +++R ++ ++ K++ RK L E + +++ ++ + E ++ E
Sbjct: 652 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE-- 709
Query: 219 EKLKRQKYDITTLRSRIDQAQKHSKK 244
++ + Q+ + R +Q + +++
Sbjct: 710 QERREQERQLAEQERRREQERLQAER 735
Score = 39.3 bits (90), Expect = 0.003
Identities = 32/152 (21%), Positives = 70/152 (46%), Gaps = 48/152 (31%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
++++ ++ EQ E+E +E+E ++ +
Sbjct: 684 LAEQREQERREQERREQERREQERREQ--------------------------------E 711
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAE----KERE 116
++ Q + L E + R++E+E L A +E E+ +A R ++++++ E K++E
Sbjct: 712 RREQERQLAE---------QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 762
Query: 117 RQNRLAEEKARREEEDAKRRAEDDLKKKKALS 148
Q RLAE + + E+E ++A++ KAL+
Sbjct: 763 EQQRLAERQLQEEQE---KKAKEAAGASKALN 791
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 62.0 bits (149), Expect = 5e-10
Identities = 55/204 (26%), Positives = 103/204 (50%), Gaps = 34/204 (16%)
Query: 4 EEVEQVEEQYEE--EEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
E VEQ++E+ ++ E++ + +E E EE EEK + K A K+ E E +
Sbjct: 582 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA-------R 634
Query: 62 KRQNKDLMELQALIDSHFEAR------KKEEEELVAL------KERIEKRRAERAEQQR- 108
++Q ++ L+ L E R KK+EEE L K E+R ER EQ+R
Sbjct: 635 RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR 694
Query: 109 --------IRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAK 160
R ++ RE++ +LAE++ RRE+E + +AE +L++++ ++ +
Sbjct: 695 EQERREQERREQERREQERQLAEQERRREQE--RLQAERELQERE--KALRLQKEQLQRE 750
Query: 161 ADQKRGKKQTAREMKKKILAERRK 184
++K+ K++ R ++++ E+ K
Sbjct: 751 LEEKKKKEEQQRLAERQLQEEQEK 774
Score = 60.1 bits (144), Expect = 2e-09
Identities = 65/261 (24%), Positives = 122/261 (46%), Gaps = 35/261 (13%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEE-----DAEEEKPRPKLTAPKIPEGEKVDFDD 58
EE EQ+ Q EE++ + EEV+ E A E + K K E + D+
Sbjct: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 604
Query: 59 IQKKRQNKDLMELQALIDS------HFEARKKEEEE---LVALKERIEKRRAERAEQQRI 109
+K + + L E +A + EAR+K+EEE L L++ E+RR + Q+
Sbjct: 605 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQK-- 662
Query: 110 RAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQ 169
+ E+E+ER + AE K E+ + +RR ++ +++ + +Q+R ++Q
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQE---------------RREQER-REQ 706
Query: 170 TAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIT 229
RE ++++ + R+ E +L+++ K L QL+ E EK K+++
Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ---RELEEKKKKEEQQRL 763
Query: 230 TLRSRIDQAQKHSKKAGTPAK 250
R ++ +K +K+A +K
Sbjct: 764 AERQLQEEQEKKAKEAAGASK 784
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/206 (17%), Positives = 95/206 (46%), Gaps = 17/206 (8%)
Query: 50 EGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRI 109
E E+ +++++K + + L + D R++ EE + +ER+ K R +++
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDK----RRRLEEVKLKREERLRKVLQARERVEQM 587
Query: 110 RAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSM-----------GANYSSYL 158
+ EK+++ + + A+ + E+ +R AE+ KKK A M A +L
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWL 647
Query: 159 AKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFG 218
+ +++R ++ ++ K++ RK L E + +++ ++ + E ++ E
Sbjct: 648 QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERRE-- 705
Query: 219 EKLKRQKYDITTLRSRIDQAQKHSKK 244
++ + Q+ + R +Q + +++
Sbjct: 706 QERREQERQLAEQERRREQERLQAER 731
Score = 39.3 bits (90), Expect = 0.003
Identities = 32/152 (21%), Positives = 70/152 (46%), Gaps = 48/152 (31%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
++++ ++ EQ E+E +E+E ++ +
Sbjct: 680 LAEQREQERREQERREQERREQERREQ--------------------------------E 707
Query: 61 KKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAE----KERE 116
++ Q + L E + R++E+E L A +E E+ +A R ++++++ E K++E
Sbjct: 708 RREQERQLAE---------QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKE 758
Query: 117 RQNRLAEEKARREEEDAKRRAEDDLKKKKALS 148
Q RLAE + + E+E ++A++ KAL+
Sbjct: 759 EQQRLAERQLQEEQE---KKAKEAAGASKALN 787
Score = 37.7 bits (86), Expect = 0.010
Identities = 43/188 (22%), Positives = 80/188 (42%), Gaps = 26/188 (13%)
Query: 20 QEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHF 79
Q E+ E+ ED E + PR K + P + V + R ++ ++ +
Sbjct: 455 QAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVV-----RPLRTFLHTVQRNQMLMTPT 509
Query: 80 EARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAED 139
A + + + +R R + E++R R E R ++ AE+ R++ E+ KRR +
Sbjct: 510 SAPRSVMKSFI---KRNTPLRMDPKEKERQRLENLRRKEE--AEQLRRQKVEEDKRRRLE 564
Query: 140 DLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILA-------ERRKPLNIDHLG 192
++K K+ L K Q R + + +E KKK + E+ + + L
Sbjct: 565 EVKLKR---------EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 615
Query: 193 EDKLRDKA 200
E+K + KA
Sbjct: 616 EEKAKKKA 623
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 61.6 bits (148), Expect = 6e-10
Identities = 57/250 (22%), Positives = 130/250 (52%), Gaps = 24/250 (9%)
Query: 7 EQVEEQY-EEEEEAQE-EEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 64
+Q EE+ +EE+ QE EE++QE EE E++ + + K+ E++ ++ +K R+
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQ--EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 65 NKDLM-----ELQALIDSHFEARKK--EEEELVALKERIEKRRAERAEQQRIRAEKERER 117
+++M +++ L + +E +K E EE + +E+I ++ +R E+++IR +++R+
Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 413
Query: 118 QNR---LAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 174
Q EEK R +EE + + + ++++ + + + ++KR +++
Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI------HEQEKIREEEKRQEQEEMWRQ 467
Query: 175 KKKILAERRKPLNIDHLGE-DKLRDKAKELW---ETLHQLEIDKFEFGEKLKRQKYDITT 230
++KI + + + E +K+R + +++W E +H E E EK+ RQ+ I
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 231 LRSRIDQAQK 240
+I + ++
Sbjct: 528 QEEKIREQEE 537
Score = 59.3 bits (142), Expect = 3e-09
Identities = 54/252 (21%), Positives = 125/252 (49%), Gaps = 25/252 (9%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + EE+ E+EE +E EE ++ K+ E++ ++ +K
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAE---RAEQQRIRAEKERERQN 119
R+ ++ M Q I E K++EEE + +E+ +++ A+ + E+ R + EK RE++
Sbjct: 380 RELEEKMHEQEKIREQEE--KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 437
Query: 120 RL--AEEKARREE---EDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 174
++ EEK +E E+ KR+ ++++ +++ + + +K +++ R+
Sbjct: 438 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE----KIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 175 KKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSR 234
++K+ + K H E+K+R++ +++W ++ E EK++ Q+ I R +
Sbjct: 494 EEKVWRQEEKM----HDQEEKIREQEEKMWRQEEKIR----EQEEKIREQEEKI---REQ 542
Query: 235 IDQAQKHSKKAG 246
+ Q+ +K G
Sbjct: 543 EEMMQEQEEKMG 554
Score = 58.2 bits (139), Expect = 7e-09
Identities = 58/234 (24%), Positives = 115/234 (49%), Gaps = 30/234 (12%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
E++ + EE+ +EEE+ +E+E+ QE A+ +EEK R + KI E EK + +K
Sbjct: 390 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ--EEKIREQEKKMWRQEEKIH 447
Query: 64 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN---R 120
+ + + E E +++E+EE+ +E+I EQ+ I +KE+ + R
Sbjct: 448 EQEKIRE---------EEKRQEQEEMWRQEEKIR-------EQEEIWRQKEKMHEQEKIR 491
Query: 121 LAEEKARREEE---DAKRRAEDDLKKKKALSSMGANYSSYLAKADQK-RGKKQTAREMKK 176
EEK R+EE D + + + +K + + ++K R +++ +E ++
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551
Query: 177 KILAERRKPLNIDHL--GEDKLR---DKAKELWETLHQLEIDKFEFGEKLKRQK 225
K+ + K + + E+K+R +K +E E + + E +E EK++ Q+
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQE 605
Score = 55.5 bits (132), Expect = 5e-08
Identities = 44/211 (20%), Positives = 110/211 (52%), Gaps = 28/211 (13%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEV--QEDTAEEDAEEEKPRPKLTAPKIP---EGEKVDFD 57
+E+ ++ EE + +EE+ +E+EE+ Q++ E + K K+ + + EK+
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQ 514
Query: 58 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKE--R 115
+ + RQ + + E + I E +++EE + +E++ ++ + EQ+++R ++E R
Sbjct: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIR 574
Query: 116 ERQNRLAEEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREM 174
E++ ++ E+K + RE+E+ E+ +++++ + Q++ +K +E
Sbjct: 575 EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM--------------QEQEEKMWEQEE 620
Query: 175 KKKILAERRKPLNIDHLGEDKLRDKAKELWE 205
K + E+ + + E+K+R + +++WE
Sbjct: 621 K---MCEQEEKMQEQ---EEKMRRQEEKMWE 645
Score = 53.9 bits (128), Expect = 1e-07
Identities = 50/241 (20%), Positives = 121/241 (50%), Gaps = 34/241 (14%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ ++EE+ E+E+ +E+EE +++ EE E++ R + A + EK+ + + +
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQE--EEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
Q K + + K E+E K R E++R E+ E R + EK RE++
Sbjct: 434 EQEKKMWR---------QEEKIHEQE----KIREEEKRQEQEEMWR-QEEKIREQEEIWR 479
Query: 123 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGK-KQTAREMKKKILAE 181
+++ E+E +++ E ++++ + + + + ++K + ++ RE ++KI +
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMH----DQEEKIREQEEKMWRQEEKIREQEEKIREQ 535
Query: 182 RRKPLNIDHLGEDKLRDKAKELWETLHQL--EIDKFEFGEKLKRQKYDITTLRSRIDQAQ 239
E+K+R++ + + E ++ + +K + EK++RQ+ I +I + +
Sbjct: 536 -----------EEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584
Query: 240 K 240
+
Sbjct: 585 E 585
Score = 52.8 bits (125), Expect = 3e-07
Identities = 56/259 (21%), Positives = 131/259 (50%), Gaps = 42/259 (16%)
Query: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQ 60
++DEE+++ + +E+ + E E+ + ++ + + R KL P+ + + + D +
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQ--QQLQAEADHLG 271
Query: 61 KKRQNKDLMELQALIDSHF---EARKKEEEELVALKERIEKRRAERAEQQ-RIRAEKERE 116
K+ Q+ +LQA ++ + +++EE++ +E+I++ + EQ+ +IR ++E+
Sbjct: 272 KELQSVSA-KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKI 330
Query: 117 RQNRLAEEKARREEE-----DAKRRAEDDL-----KKKKALSSM-------------GAN 153
R+ EEK RR+EE + K R ++++ +K + L M +
Sbjct: 331 REQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 154 YSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHL--GEDKLRDKAKELW---ETLH 208
+ + ++KR +++ RE +K+ E + + + E+K+R++ K++W E +H
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 209 QLEIDKFEFGEKLKRQKYD 227
+ E + E+ KRQ+ +
Sbjct: 448 EQE----KIREEEKRQEQE 462
Score = 50.1 bits (118), Expect = 2e-06
Identities = 30/131 (22%), Positives = 70/131 (53%), Gaps = 3/131 (2%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + EE+ E+EE +E+E + EE +E++ + + EK+ + +
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 588
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERI---EKRRAERAEQQRIRAEKERERQN 119
Q + + E + I E +++EE++ +E++ E++ E+ E+ R + EK E++
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Query: 120 RLAEEKARREE 130
RL +++ + +E
Sbjct: 649 RLRQQEEKMQE 659
Score = 37.0 bits (84), Expect = 0.017
Identities = 30/120 (25%), Positives = 56/120 (46%), Gaps = 14/120 (11%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
EE Q +E+ +EE E+ EE E+K KI E E+ ++ +K R
Sbjct: 557 EEKMQEQEKMRRQEEKIREQ-------EEKIREQK-------EKIREQEEKIWEQEEKIR 602
Query: 64 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 123
+ +++M+ Q E + E+EE + +E +R+ E+ +Q +R ++ E+ E
Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Score = 32.7 bits (73), Expect = 0.32
Identities = 21/85 (24%), Positives = 41/85 (48%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
EQ E+ E+EE+ E+EE + E E+E+ + + EK+ + + +RQ +
Sbjct: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 67 DLMELQALIDSHFEARKKEEEELVA 91
+ E + + E ++ +E L A
Sbjct: 642 KMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 30.4 bits (67), Expect = 1.6
Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 10/79 (12%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E++ + EE +E+EE E+E + EE +E++ + + K+ E E ++ +
Sbjct: 598 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE------VRLR 651
Query: 63 RQNKDLMELQALIDSHFEA 81
+Q + + E Q H EA
Sbjct: 652 QQEEKMQEHQ----EHLEA 666
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 61.2 bits (147), Expect = 8e-10
Identities = 53/212 (25%), Positives = 106/212 (50%), Gaps = 17/212 (8%)
Query: 3 DEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKK 62
+E + + EE+ E+EE E+E + EE E++ R + ++ E E+ + +
Sbjct: 198 EERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEE------RLR 251
Query: 63 RQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLA 122
+ L E + + E +++EE L +ER+ E+ E+ R + E+ E++ RL
Sbjct: 252 EHEERLCEQEERLCEQEERLREQEERLHEQEERL----CEQEERLREQEERLCEQEERLR 307
Query: 123 EEKARR-EEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAE 181
E++ R E+E+ R E+ L +++ L +Q+R +++ R ++++ L E
Sbjct: 308 EQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLE 367
Query: 182 RRKPLNIDHLGEDKLRDKAKELW--ETLHQLE 211
+ L L +++LR + + LW ETL +LE
Sbjct: 368 EVEEL----LEQERLRQQDERLWQQETLQELE 395
Score = 42.7 bits (99), Expect = 3e-04
Identities = 46/198 (23%), Positives = 95/198 (47%), Gaps = 16/198 (8%)
Query: 45 APKIPEG-EKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAER 103
AP+ P G KV+ Q + + L + + +A + + L L R E+R E+
Sbjct: 149 APEPPAGPSKVE----QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQ 204
Query: 104 AEQQRIRAEKERERQNRLAEEKAR-REEEDAKRRAEDDLKKKKALSSMGANYSSYLAKAD 162
E+ R + E+ RE++ RL E++ R RE+E+ R E+ L +++ + L + +
Sbjct: 205 EERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQE---ERLREHEERLCEQE 261
Query: 163 QKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLK 222
++ +++ +++ L E+ + L E++LR++ + L E +L E E+L
Sbjct: 262 ERLCEQEERLREQEERLHEQEERLCEQ---EERLREQEERLCEQEERLR----EQEERLC 314
Query: 223 RQKYDITTLRSRIDQAQK 240
Q+ + R+ + +K
Sbjct: 315 EQEERLREQEERLCEQEK 332
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 60.5 bits (145), Expect = 1e-09
Identities = 69/279 (24%), Positives = 126/279 (45%), Gaps = 53/279 (18%)
Query: 5 EVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQ 64
+++ + + E E+E +E E T EE A E R +L + ++ + +Q + +
Sbjct: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSE 898
Query: 65 NKDLME--------------LQALIDSHFEARKKEEE---ELVALKERIE------KRRA 101
++LM+ L+A + E ++EEE ELVA K +E KR
Sbjct: 899 TENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDI 958
Query: 102 ERAEQQRIRAEKERE----RQNRLAEEKARREE------------EDAKRRAEDDLK--K 143
+ E + EKE+ + L+EE EE ++A ++ DDL+ +
Sbjct: 959 DDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEE 1018
Query: 144 KKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKEL 203
K + N AK +Q+ + + E +KK+ A+ + + KL K
Sbjct: 1019 DKVNGLIKIN-----AKLEQQTDDLEGSLEQEKKLRADLER-------AKRKLEGDLKMS 1066
Query: 204 WETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 242
E++ LE DK + EKLK+++++++ L+++ID Q HS
Sbjct: 1067 QESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHS 1105
Score = 44.7 bits (104), Expect = 8e-05
Identities = 54/238 (22%), Positives = 101/238 (42%), Gaps = 28/238 (11%)
Query: 8 QVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKD 67
++E+Q ++ E + E+E+ E + + K++ I + E D I++K + K+
Sbjct: 1030 KLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEN-DKQQIEEKLKKKE 1088
Query: 68 --LMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQN---RLA 122
L +LQA ID + ++++ L+ RIE+ E + +RA+ E++R + L
Sbjct: 1089 FELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELE 1148
Query: 123 EEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAER 182
E R EE A+ ++ KK+ A+ + R + A + A
Sbjct: 1149 EISERLEEASGATSAQIEMNKKRE------------AEFQKMRRDLEEATLQHEATAATL 1196
Query: 183 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQK 240
RK K D EL E + L+ K + ++ K +I + S I+ K
Sbjct: 1197 RK----------KQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSK 1244
Score = 40.4 bits (93), Expect = 0.002
Identities = 50/244 (20%), Positives = 114/244 (46%), Gaps = 13/244 (5%)
Query: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQK 61
S + + + EQYEEE+EA + E+Q ++ ++E + R K I E+++ +
Sbjct: 1340 SRHDCDLLREQYEEEQEA--KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1397
Query: 62 KRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNR- 120
++ ++ E +S + +K ++ L E + R ER+ +K++ ++
Sbjct: 1398 AQRLQEAEENTETANSKCASLEKTKQRLQGEVEDL-MRDLERSHTACATLDKKQRNFDKV 1456
Query: 121 LAEEKARREEEDAKRRAEDDLKKKKALSS-MGANYSSYLAKADQKRGKKQTAREMKKKI- 178
LAE K + +E A+ A K+ ++LS+ + ++Y DQ ++ + ++++I
Sbjct: 1457 LAEWKQKLDESQAELEAAQ--KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEIS 1514
Query: 179 -----LAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRS 233
+AE K L + + + +L L ++E K+ R + +++ ++S
Sbjct: 1515 DLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKS 1574
Query: 234 RIDQ 237
+D+
Sbjct: 1575 ELDR 1578
Score = 35.4 bits (80), Expect = 0.050
Identities = 46/197 (23%), Positives = 92/197 (46%), Gaps = 46/197 (23%)
Query: 63 RQNKDLMELQALIDSH------------------FEARKKEEEELVALKERIE------- 97
R N+DL E A+++ R+ E+EL+ +R++
Sbjct: 1666 RSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNT 1725
Query: 98 -----KRRAERAEQQRIRAEKERE-RQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMG 151
K++ E A+ + +AE E +++R AEEKA++ DA AE +LKK++
Sbjct: 1726 SLINTKKKLE-ADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAE-ELKKEQ------ 1777
Query: 152 ANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLE 211
+ S++L + K+ +QT ++++ ++ + L KL ++ +EL ++L+
Sbjct: 1778 -DTSAHLER--MKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVREL---ENELD 1831
Query: 212 IDKFEFGEKLK-RQKYD 227
+++ E LK KY+
Sbjct: 1832 VEQKRGAEALKGAHKYE 1848
Score = 34.3 bits (77), Expect = 0.11
Identities = 47/247 (19%), Positives = 95/247 (38%), Gaps = 47/247 (19%)
Query: 5 EVEQVEEQYEEEE-------EAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFD 57
E+E++ E+ EE E ++ E + D EE + + TA +
Sbjct: 1146 ELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATL--------- 1196
Query: 58 DIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERER 117
+K+Q + EL ID+ L +K+++EK ++E ++ E +
Sbjct: 1197 ---RKKQADSVAELGEQIDN-----------LQRVKQKLEKEKSE------LKMEIDDMA 1236
Query: 118 QNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGA----NYSSYLAKADQKRGKKQTARE 173
N A K++ E R ED + KA + + A+ + G+ E
Sbjct: 1237 SNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVE 1296
Query: 174 MKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRS 233
K+ ++++ K + L + +EL + + K L+ ++D LR
Sbjct: 1297 EKESLISQLTK-------SKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349
Query: 234 RIDQAQK 240
+ ++ Q+
Sbjct: 1350 QYEEEQE 1356
Score = 33.5 bits (75), Expect = 0.19
Identities = 40/147 (27%), Positives = 66/147 (44%), Gaps = 22/147 (14%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKR 63
+E EQ+ + +++ + E V+E E D E+++ L E KV Q +
Sbjct: 1802 DEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYE-RKVKEMTYQAEE 1860
Query: 64 QNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAE 123
+K+++ LQ L+D + K + KR+AE AE+Q A + R R+
Sbjct: 1861 DHKNILRLQDLVDK------------LQAKVKSYKRQAEEAEEQ---ANTQLSRCRRVQH 1905
Query: 124 EKARREEEDAKRR--AEDDLKKKKALS 148
E EE A+R AE + K +A S
Sbjct: 1906 EL----EEAAERADIAESQVNKLRAKS 1928
Score = 28.5 bits (62), Expect = 6.1
Identities = 56/255 (21%), Positives = 108/255 (42%), Gaps = 43/255 (16%)
Query: 9 VEEQYEEEEEAQEEEEVQ--EDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
VE+Q+ E + A++E++ Q D + A + +L+ ++ E E + I + ++K
Sbjct: 1256 VEDQFSEIK-AKDEQQTQLIHDLNMQKARLQTQNGELSH-RVEEKESL----ISQLTKSK 1309
Query: 67 DLMELQALIDSHFEARKKEEEE----------LVALKERIEKRRAERAEQQRIRAEKER- 115
QAL E +++ EEE L + + + R + E+Q +AE +R
Sbjct: 1310 -----QALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRA 1364
Query: 116 -ERQNRLAEEKARREEEDAKRRAE--DDLKKKKALSSMGANYSSYLAKADQKRGKKQTAR 172
+ N + + E DA +R E ++ KKK A A ++ A + K +
Sbjct: 1365 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANS-----KCASLE 1419
Query: 173 EMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLR 232
+ K+++ E ED +RD + L+ + F + L K + +
Sbjct: 1420 KTKQRLQGE----------VEDLMRDLERS-HTACATLDKKQRNFDKVLAEWKQKLDESQ 1468
Query: 233 SRIDQAQKHSKKAGT 247
+ ++ AQK S+ T
Sbjct: 1469 AELEAAQKESRSLST 1483
>gi|15149465 caldesmon 1 isoform 5 [Homo sapiens]
Length = 532
Score = 59.7 bits (143), Expect = 2e-09
Identities = 57/227 (25%), Positives = 100/227 (44%), Gaps = 48/227 (21%)
Query: 4 EEVEQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPR-----------PKLTAPKIPEGE 52
EE E V + Y++ + EE +ED +E+ EEEKP+ K+ K P+ E
Sbjct: 157 EETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEE 216
Query: 53 KVDFDDIQK-----KRQNKDLMELQALIDSH----------FEARKKEEEELVALKERIE 97
F D +K K QN + M + + + ++ E V +R+E
Sbjct: 217 VKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE 276
Query: 98 KRRAERAEQQRIRAEKERERQNRLA---EEKARREEEDAKRRAEDDLKKKKALSSMGANY 154
+ R R E + EK +++Q A EE ++ EE K E++ ++K+
Sbjct: 277 ELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ--------- 327
Query: 155 SSYLAKADQKRGKKQTAREMKKKI------LAERRKPLNIDHLGEDK 195
+AD+K +++ R +K++I AE+R+ + D L +DK
Sbjct: 328 ----EEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDK 370
Score = 42.0 bits (97), Expect = 5e-04
Identities = 46/158 (29%), Positives = 76/158 (48%), Gaps = 25/158 (15%)
Query: 30 AEEDAEEEKPRPKLTAPKI--------PEGEKVDFDDIQKKRQNKDLMELQALIDSHFEA 81
A D +E + P++ A K E E +F+ +++K+Q L EL+ L E
Sbjct: 256 ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAAL-ELEELKKKREER 314
Query: 82 RKKEEEELVALKERIEKRRAE---RAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAE 138
RK EEE ++R ++ A+ R E+++ R ++E ER+ A EK ++ ED
Sbjct: 315 RKVLEEE----EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDG---LS 367
Query: 139 DDLKKKKALSSMGANY-----SSYLAKADQK-RGKKQT 170
DD K K + G++ + +L K+ QK G K T
Sbjct: 368 DDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKST 405
Score = 30.8 bits (68), Expect = 1.2
Identities = 30/166 (18%), Positives = 65/166 (39%), Gaps = 28/166 (16%)
Query: 7 EQVEEQYEEEEEAQEEEEVQEDTAEEDAEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNK 66
E++ ++ EEE Q ++V E A+ +E+ + T ++ ++ F + +R+ +
Sbjct: 42 ERLRQKQEEESLGQVTDQV-EVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREER 100
Query: 67 DLMELQ-----------ALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKER 115
LQ + D+ + + A E EK + Q+R E+
Sbjct: 101 RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETE 160
Query: 116 E-------------RQNRLAEEKARREEEDAKRR---AEDDLKKKK 145
+N+ +++ EEE+ +R E+ +K +K
Sbjct: 161 TVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEK 206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.125 0.326
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,247,366
Number of Sequences: 37866
Number of extensions: 568025
Number of successful extensions: 31555
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 964
Number of HSP's successfully gapped in prelim test: 1097
Number of HSP's that attempted gapping in prelim test: 6279
Number of HSP's gapped (non-prelim): 10349
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.