Search of human proteins with 5803133

Search of human proteins with 5803133

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5803133 RAB32, member RAS oncogene family [Homo sapiens]
         (225 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5803133 RAB32, member RAS oncogene family [Homo sapiens]           457   e-129
gi|11641237 RAB38 [Homo sapiens]                                      278   3e-75
gi|208609962 RAB7, member RAS oncogene family-like 1 isoform 1 [...   217   7e-57
gi|4506375 RAB7, member RAS oncogene family-like 1 isoform 1 [Ho...   217   7e-57
gi|208609964 RAB7, member RAS oncogene family-like 1 isoform 2 [...   167   7e-42
gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]      134   8e-32
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]           130   7e-31
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa...   129   3e-30
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]            129   3e-30
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]            129   3e-30
gi|50234889 RAB43 protein [Homo sapiens]                              123   1e-28
gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]           122   2e-28
gi|38490537 RAB7B, member RAS oncogene family [Homo sapiens]          122   3e-28
gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]           121   4e-28
gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]         121   4e-28
gi|16933567 mel transforming oncogene [Homo sapiens]                  120   7e-28
gi|34147513 RAB7, member RAS oncogene family [Homo sapiens]           120   1e-27
gi|208609966 RAB7, member RAS oncogene family-like 1 isoform 3 [...   119   2e-27
gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]         117   1e-26
gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]          115   2e-26
gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]           115   4e-26
gi|21361884 RAB2B protein isoform 1 [Homo sapiens]                    114   5e-26
gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]        114   7e-26
gi|4758984 Ras-related protein Rab-11A [Homo sapiens]                 114   7e-26
gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]           114   9e-26
gi|19923483 GTPase Rab14 [Homo sapiens]                               113   1e-25
gi|82659107 ras-related GTP-binding protein 4b [Homo sapiens]         111   4e-25
gi|19923750 RAB3B, member RAS oncogene family [Homo sapiens]          111   6e-25
gi|19923260 RAB4A, member RAS oncogene family [Homo sapiens]          111   6e-25
gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]           111   6e-25

>gi|5803133 RAB32, member RAS oncogene family [Homo sapiens]
          Length = 225

 Score =  457 bits (1176), Expect = e-129
 Identities = 225/225 (100%), Positives = 225/225 (100%)

Query: 1   MAGGGAGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGV 60
           MAGGGAGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGV
Sbjct: 1   MAGGGAGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGV 60

Query: 61  DFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKW 120
           DFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKW
Sbjct: 61  DFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKW 120

Query: 121 KSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNIN 180
           KSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNIN
Sbjct: 121 KSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNIN 180

Query: 181 IEEAARFLVEKILVNHQSFPNEENDVDKIKLDQETLRAENKSQCC 225
           IEEAARFLVEKILVNHQSFPNEENDVDKIKLDQETLRAENKSQCC
Sbjct: 181 IEEAARFLVEKILVNHQSFPNEENDVDKIKLDQETLRAENKSQCC 225


>gi|11641237 RAB38 [Homo sapiens]
          Length = 211

 Score =  278 bits (711), Expect = 3e-75
 Identities = 132/175 (75%), Positives = 154/175 (88%), Gaps = 1/175 (0%)

Query: 22  REHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWD 81
           +EHL+K+LVIG+LGVGKTSIIKRYVHQ FS HYRATIGVDFALKVL+WD  T+VRLQLWD
Sbjct: 6   KEHLYKLLVIGDLGVGKTSIIKRYVHQNFSSHYRATIGVDFALKVLHWDPETVVRLQLWD 65

Query: 82  IAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLL 141
           IAGQERFGNMTRVYY+EA+GAF+VFD++R +TFEAV KWK+DLDSK+ LPNG P+  VLL
Sbjct: 66  IAGQERFGNMTRVYYREAMGAFIVFDVTRPATFEAVAKWKNDLDSKLSLPNGKPVSVVLL 125

Query: 142 ANKCDQNKDSSQSPS-QVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVN 195
           ANKCDQ KD   +   ++DQFCKEHGF GWFETSAK+NINI+EA+R LV+ IL N
Sbjct: 126 ANKCDQGKDVLMNNGLKMDQFCKEHGFVGWFETSAKENINIDEASRCLVKHILAN 180


>gi|208609962 RAB7, member RAS oncogene family-like 1 isoform 1
           [Homo sapiens]
          Length = 203

 Score =  217 bits (552), Expect = 7e-57
 Identities = 104/208 (50%), Positives = 144/208 (69%), Gaps = 10/208 (4%)

Query: 21  TREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLW 80
           +R+HLFKVLV+G+  VGKTS+++RY    FS+HY++T+GVDFALKVL W    +VRLQLW
Sbjct: 3   SRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDYEIVRLQLW 62

Query: 81  DIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVL 140
           DIAGQERF +MTR+YY++A    ++FD++ ++TF    +WK DLDSK+ LPNG P+P +L
Sbjct: 63  DIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPCLL 122

Query: 141 LANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFP 200
           LANKCD +   + S  Q+D+F KE+GF GW ETS K+N NI EA R L+EK++       
Sbjct: 123 LANKCDLS-PWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMM------R 175

Query: 201 NEENDVDKIKLDQETLRAENKS---QCC 225
           N   D+  +    + +  + KS    CC
Sbjct: 176 NSTEDIMSLSTQGDYINLQTKSSSWSCC 203


>gi|4506375 RAB7, member RAS oncogene family-like 1 isoform 1 [Homo
           sapiens]
          Length = 203

 Score =  217 bits (552), Expect = 7e-57
 Identities = 104/208 (50%), Positives = 144/208 (69%), Gaps = 10/208 (4%)

Query: 21  TREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLW 80
           +R+HLFKVLV+G+  VGKTS+++RY    FS+HY++T+GVDFALKVL W    +VRLQLW
Sbjct: 3   SRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVGVDFALKVLQWSDYEIVRLQLW 62

Query: 81  DIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVL 140
           DIAGQERF +MTR+YY++A    ++FD++ ++TF    +WK DLDSK+ LPNG P+P +L
Sbjct: 63  DIAGQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPCLL 122

Query: 141 LANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFP 200
           LANKCD +   + S  Q+D+F KE+GF GW ETS K+N NI EA R L+EK++       
Sbjct: 123 LANKCDLS-PWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMM------R 175

Query: 201 NEENDVDKIKLDQETLRAENKS---QCC 225
           N   D+  +    + +  + KS    CC
Sbjct: 176 NSTEDIMSLSTQGDYINLQTKSSSWSCC 203


>gi|208609964 RAB7, member RAS oncogene family-like 1 isoform 2
           [Homo sapiens]
          Length = 179

 Score =  167 bits (423), Expect = 7e-42
 Identities = 86/208 (41%), Positives = 125/208 (60%), Gaps = 34/208 (16%)

Query: 21  TREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLW 80
           +R+HLFKVLV+G+  VGKTS+++RY    FS+HY++T+G                     
Sbjct: 3   SRDHLFKVLVVGDAAVGKTSLVQRYSQDSFSKHYKSTVG--------------------- 41

Query: 81  DIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVL 140
              GQERF +MTR+YY++A    ++FD++ ++TF    +WK DLDSK+ LPNG P+P +L
Sbjct: 42  ---GQERFTSMTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPCLL 98

Query: 141 LANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFP 200
           LANKCD +   + S  Q+D+F KE+GF GW ETS K+N NI EA R L+EK++       
Sbjct: 99  LANKCDLS-PWAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMM------R 151

Query: 201 NEENDVDKIKLDQETLRAENKS---QCC 225
           N   D+  +    + +  + KS    CC
Sbjct: 152 NSTEDIMSLSTQGDYINLQTKSSSWSCC 179


>gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]
          Length = 200

 Score =  134 bits (336), Expect = 8e-32
 Identities = 76/208 (36%), Positives = 119/208 (57%), Gaps = 9/208 (4%)

Query: 18  APETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRL 77
           A +T + LFK+L+IG+ GVGKT ++ R+    F+  + +TIG+DF +K +    +  ++L
Sbjct: 2   AKKTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKK-IKL 60

Query: 78  QLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIP 137
           Q+WD AGQERF  +T  YY+ A+G  +V+DI+   +FE + KW  ++D   +      + 
Sbjct: 61  QIWDTAGQERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHAN----EDVE 116

Query: 138 AVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQ 197
            +LL NKCD +        +  Q  +EHG   +FETSAK NINIE+A   L E IL   +
Sbjct: 117 RMLLGNKCDMDDKRVVPKGKGGQIAREHGIR-FFETSAKANINIEKAFLTLAEDIL---R 172

Query: 198 SFPNEENDVDKIKLDQETLRAENKSQCC 225
             P +E + + + +         KS+CC
Sbjct: 173 KTPVKEPNSENVDISSGGGVTGWKSKCC 200


>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score =  130 bits (328), Expect = 7e-31
 Identities = 65/172 (37%), Positives = 103/172 (59%), Gaps = 6/172 (3%)

Query: 23  EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDI 82
           +HLFK+L+IG+ GVGKT +I R+    F+  Y +TIG+DF ++ ++ + +  ++LQ+WD 
Sbjct: 6   DHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKK-IKLQVWDT 64

Query: 83  AGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLA 142
           AGQERF  +T  YY+ A+G  +V+DI+   +FE +  W   +         + +  +LL 
Sbjct: 65  AGQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENA----SAGVERLLLG 120

Query: 143 NKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILV 194
           NKCD          Q D+  +EHG   +FETSAK ++N++EA   L   IL+
Sbjct: 121 NKCDMEAKRKVQKEQADKLAREHGIR-FFETSAKSSMNVDEAFSSLARDILL 171


>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
           family [Homo sapiens]
          Length = 327

 Score =  129 bits (323), Expect = 3e-30
 Identities = 69/186 (37%), Positives = 109/186 (58%), Gaps = 14/186 (7%)

Query: 16  APAP------ETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNW 69
           +PAP      +  +HLFK+L+IG+ GVGKT +I R+    F+  Y +TIG+DF ++ ++ 
Sbjct: 117 SPAPPVSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDI 176

Query: 70  DSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVH 129
           + +  ++LQ+WD AGQERF  +T  YY+ A+G  + +DI+   +FE +  W   +     
Sbjct: 177 EGKK-IKLQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSI----- 230

Query: 130 LPNGSP-IPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFL 188
           + N S  +  +LL NKCD          Q D+  +EHG   +FETSAK ++N++EA   L
Sbjct: 231 MENASAGVEHLLLGNKCDMEAKRKVQKEQADKLAREHGIR-FFETSAKSSMNVDEAFSSL 289

Query: 189 VEKILV 194
              IL+
Sbjct: 290 ARDILL 295


>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score =  129 bits (323), Expect = 3e-30
 Identities = 69/186 (37%), Positives = 109/186 (58%), Gaps = 14/186 (7%)

Query: 16  APAP------ETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNW 69
           +PAP      +  +HLFK+L+IG+ GVGKT +I R+    F+  Y +TIG+DF ++ ++ 
Sbjct: 117 SPAPPVSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDI 176

Query: 70  DSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVH 129
           + +  ++LQ+WD AGQERF  +T  YY+ A+G  + +DI+   +FE +  W   +     
Sbjct: 177 EGKK-IKLQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSI----- 230

Query: 130 LPNGSP-IPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFL 188
           + N S  +  +LL NKCD          Q D+  +EHG   +FETSAK ++N++EA   L
Sbjct: 231 MENASAGVEHLLLGNKCDMEAKRKVQKEQADKLAREHGIR-FFETSAKSSMNVDEAFSSL 289

Query: 189 VEKILV 194
              IL+
Sbjct: 290 ARDILL 295


>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
          Length = 327

 Score =  129 bits (323), Expect = 3e-30
 Identities = 69/186 (37%), Positives = 109/186 (58%), Gaps = 14/186 (7%)

Query: 16  APAP------ETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNW 69
           +PAP      +  +HLFK+L+IG+ GVGKT +I R+    F+  Y +TIG+DF ++ ++ 
Sbjct: 117 SPAPPVSAMAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDI 176

Query: 70  DSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVH 129
           + +  ++LQ+WD AGQERF  +T  YY+ A+G  + +DI+   +FE +  W   +     
Sbjct: 177 EGKK-IKLQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFENIQNWMKSI----- 230

Query: 130 LPNGSP-IPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFL 188
           + N S  +  +LL NKCD          Q D+  +EHG   +FETSAK ++N++EA   L
Sbjct: 231 MENASAGVEHLLLGNKCDMEAKRKVQKEQADKLAREHGIR-FFETSAKSSMNVDEAFSSL 289

Query: 189 VEKILV 194
              IL+
Sbjct: 290 ARDILL 295


>gi|50234889 RAB43 protein [Homo sapiens]
          Length = 212

 Score =  123 bits (308), Expect = 1e-28
 Identities = 73/214 (34%), Positives = 117/214 (54%), Gaps = 14/214 (6%)

Query: 3   GGGAGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDF 62
           G G GDP          E  + LFK++++G+  VGKT +++R+    FS+   +TIGVDF
Sbjct: 5   GPGPGDPD---------EQYDFLFKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDF 55

Query: 63  ALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKS 122
            +K L    +  V+LQ+WD AGQERF  +T+ YY+ A GA + +DI++ S+F +V  W  
Sbjct: 56  TMKTLEIQGKR-VKLQIWDTAGQERFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIE 114

Query: 123 DLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIE 182
           D    V    GS I  +L+ NK D ++    S ++     + +      ETSAKD+ N+E
Sbjct: 115 D----VRKYAGSNIVQLLIGNKSDLSELREVSLAEAQSLAEHYDILCAIETSAKDSSNVE 170

Query: 183 EAARFLVEKILVNHQSFPNEENDVDKIKLDQETL 216
           EA   +  ++++ H      E   D I+L+ + +
Sbjct: 171 EAFLRVATELIMRHGGPLFSEKSPDHIQLNSKDI 204


>gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]
          Length = 207

 Score =  122 bits (306), Expect = 2e-28
 Identities = 62/185 (33%), Positives = 107/185 (57%), Gaps = 6/185 (3%)

Query: 20  ETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQL 79
           +T ++LFK+L+IG+ GVGKT ++ R+    F+  + +TIG+DF ++ +  D +  ++LQ+
Sbjct: 3   KTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKK-IKLQI 61

Query: 80  WDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAV 139
           WD AGQERF  +T  YY+ A+G  +V+DI+   +F+ +  W  +++        S +  +
Sbjct: 62  WDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHA----SSDVERM 117

Query: 140 LLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSF 199
           +L NKCD N     S  + ++   ++G   + ETSAK + N+EEA   L   I+      
Sbjct: 118 ILGNKCDMNDKRQVSKERGEKLAIDYGIK-FLETSAKSSANVEEAFFTLARDIMTKLNRK 176

Query: 200 PNEEN 204
            N+ N
Sbjct: 177 MNDSN 181


>gi|38490537 RAB7B, member RAS oncogene family [Homo sapiens]
          Length = 199

 Score =  122 bits (305), Expect = 3e-28
 Identities = 71/200 (35%), Positives = 117/200 (58%), Gaps = 11/200 (5%)

Query: 27  KVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQE 86
           K++++G +GVGKTS+  +YVH+ F + Y+ T+G     K++     TL +LQ+WD  GQE
Sbjct: 10  KLIIVGAIGVGKTSLPHQYVHKTFYEEYQTTLGASILSKIIILGDTTL-KLQIWDTGGQE 68

Query: 87  RFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCD 146
           RF +M   +YK + G  + FD++   +FEA+  W+ D+ +K+ +P     P VLL NK D
Sbjct: 69  RFRSMVSTFYKGSDGCILAFDVTDLESFEALDIWRGDVLAKI-VPMEQSYPMVLLGNKID 127

Query: 147 QNKDSSQSPSQVDQ-FCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFPNEEND 205
                 + P +V Q +C+E     +FE SAK++IN+ +A   L  + L  +QS   E + 
Sbjct: 128 --LADRKVPQEVAQGWCREKDIP-YFEVSAKNDINVVQAFEMLASRALSRYQSI-LENHL 183

Query: 206 VDKIKLDQETLRAENKSQCC 225
            + IKL  +    +++S+CC
Sbjct: 184 TESIKLSPD----QSRSRCC 199


>gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score =  121 bits (304), Expect = 4e-28
 Identities = 69/206 (33%), Positives = 114/206 (55%), Gaps = 13/206 (6%)

Query: 23  EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDI 82
           +HLFK+L+IG+ GVGK+S++ R+    FS  Y  TIGVDF ++ +  +    V+LQ+WD 
Sbjct: 6   DHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEK-VKLQIWDT 64

Query: 83  AGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLA 142
           AGQERF  +T  YY+   G  VV+D++ + +F  V +W  +++      N   +  +L+ 
Sbjct: 65  AGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQ-----NCDDVCRILVG 119

Query: 143 NKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKIL---VNHQSF 199
           NK D  +          +F  + G    FETSAK+N+N+EE    + E +L    ++ + 
Sbjct: 120 NKNDDPERKVVETEDAYKFAGQMGIQ-LFETSAKENVNVEEMFNCITELVLRAKKDNLAK 178

Query: 200 PNEENDVDKIKLDQETLRAENKSQCC 225
             ++   D +KL   T  ++ K +CC
Sbjct: 179 QQQQQQNDVVKL---TKNSKRKKRCC 201


>gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]
          Length = 244

 Score =  121 bits (304), Expect = 4e-28
 Identities = 68/195 (34%), Positives = 106/195 (54%), Gaps = 9/195 (4%)

Query: 3   GGGAGDPGL----GAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATI 58
           G GAG P L    G      P   +   +V++IG  GVGKTS+++R+    F +  ++T+
Sbjct: 16  GLGAGSPALSGGQGRRRKQPPRPADFKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTV 75

Query: 59  GVDFALKVLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVL 118
           GVDF +K +    +  +RLQ+WD AGQERF ++T  YY+ A G  +V+DI++  TF+ + 
Sbjct: 76  GVDFKIKTVELRGKK-IRLQIWDTAGQERFNSITSAYYRSAKGIILVYDITKKETFDDLP 134

Query: 119 KWKSDLDSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDN 178
           KW   +D             +L+ NK D   D   +  Q ++F ++     + E SAKDN
Sbjct: 135 KWMKMIDKYA----SEDAELLLVGNKLDCETDREITRQQGEKFAQQITGMRFCEASAKDN 190

Query: 179 INIEEAARFLVEKIL 193
            N++E    LV+ IL
Sbjct: 191 FNVDEIFLKLVDDIL 205


>gi|16933567 mel transforming oncogene [Homo sapiens]
          Length = 207

 Score =  120 bits (302), Expect = 7e-28
 Identities = 66/200 (33%), Positives = 111/200 (55%), Gaps = 11/200 (5%)

Query: 20  ETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQL 79
           +T ++LFK+L+IG+ GVGKT ++ R+    F+  + +TIG+DF ++ +  D +  ++LQ+
Sbjct: 3   KTYDYLFKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKR-IKLQI 61

Query: 80  WDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAV 139
           WD AGQERF  +T  YY+ A+G  +V+DI+   +F+ +  W  +++        + +  +
Sbjct: 62  WDTAGQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHA----SADVEKM 117

Query: 140 LLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVN---- 195
           +L NKCD N     S  + ++   ++G   + ETSAK NIN+E A   L   I       
Sbjct: 118 ILGNKCDVNDKRQVSKERGEKLALDYGIK-FMETSAKANINVENAFFTLARDIKAKMDKK 176

Query: 196 -HQSFPNEENDVDKIKLDQE 214
              + P   N   KI  DQ+
Sbjct: 177 LEGNSPQGSNQGVKITPDQQ 196


>gi|34147513 RAB7, member RAS oncogene family [Homo sapiens]
          Length = 207

 Score =  120 bits (300), Expect = 1e-27
 Identities = 70/202 (34%), Positives = 114/202 (56%), Gaps = 5/202 (2%)

Query: 25  LFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAG 84
           L KV+++G+ GVGKTS++ +YV++ FS  Y+ATIG DF  K +  D R LV +Q+WD AG
Sbjct: 8   LLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDR-LVTMQIWDTAG 66

Query: 85  QERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANK 144
           QERF ++   +Y+ A    +VFD++  +TF+ +  W+ +   +    +    P V+L NK
Sbjct: 67  QERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNK 126

Query: 145 CD-QNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFPNEE 203
            D +N+  +   +Q   +C       +FETSAK+ IN+E+A + +    L          
Sbjct: 127 IDLENRQVATKRAQA--WCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYN 184

Query: 204 NDVDKIKLDQETLRAENKSQCC 225
              + IKLD+   RA+  ++ C
Sbjct: 185 EFPEPIKLDKND-RAKASAESC 205


>gi|208609966 RAB7, member RAS oncogene family-like 1 isoform 3
           [Homo sapiens]
          Length = 131

 Score =  119 bits (298), Expect = 2e-27
 Identities = 59/138 (42%), Positives = 86/138 (62%), Gaps = 10/138 (7%)

Query: 91  MTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLANKCDQNKD 150
           MTR+YY++A    ++FD++ ++TF    +WK DLDSK+ LPNG P+P +LLANKCD +  
Sbjct: 1   MTRLYYRDASACVIMFDVTNATTFSNSQRWKQDLDSKLTLPNGEPVPCLLLANKCDLS-P 59

Query: 151 SSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSFPNEENDVDKIK 210
            + S  Q+D+F KE+GF GW ETS K+N NI EA R L+EK++       N   D+  + 
Sbjct: 60  WAVSRDQIDRFSKENGFTGWTETSVKENKNINEAMRVLIEKMM------RNSTEDIMSLS 113

Query: 211 LDQETLRAENKS---QCC 225
              + +  + KS    CC
Sbjct: 114 TQGDYINLQTKSSSWSCC 131


>gi|239915976 RAB19, member RAS oncogene family [Homo sapiens]
          Length = 217

 Score =  117 bits (292), Expect = 1e-26
 Identities = 63/212 (29%), Positives = 121/212 (57%), Gaps = 6/212 (2%)

Query: 13  AAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSR 72
           ++A  A E  ++LFK+++IG+  VGKT +++ +   ++++  + TIGVDF ++ L+ D +
Sbjct: 5   SSARAADENFDYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGK 64

Query: 73  TLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPN 132
             V++Q+WD AGQERF  +T+ YY+ A  A + +D++R STFE++  W  +++       
Sbjct: 65  K-VKMQVWDTAGQERFRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKY----G 119

Query: 133 GSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKI 192
            + +  +L+ NKCD  +             +++G     ETSAK++ NIEE    + +++
Sbjct: 120 AANVVIMLIGNKCDLWEKRHVLFEDACTLAEKYGLLAVLETSAKESKNIEEVFVLMAKEL 179

Query: 193 LVNHQSFPNEENDVDKIKLDQE-TLRAENKSQ 223
           +  +      E+ ++ + LD    L A+  S+
Sbjct: 180 IARNSLHLYGESALNGLPLDSSPVLMAQGPSE 211


>gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]
          Length = 227

 Score =  115 bits (289), Expect = 2e-26
 Identities = 60/170 (35%), Positives = 104/170 (61%), Gaps = 6/170 (3%)

Query: 23  EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDI 82
           +++FK+L+IG   VGKTS + RY    F+  + +T+G+DF +K + + +   ++LQ+WD 
Sbjct: 28  DYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTV-FKNEKRIKLQIWDT 86

Query: 83  AGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLA 142
           AGQER+  +T  YY+ A+G  +++DI+   +F AV  W + +  K +  + + +  +L+ 
Sbjct: 87  AGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI--KTYSWDNAQV--ILVG 142

Query: 143 NKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKI 192
           NKCD   +   S  +     ++ GF  +FETSAKDNIN+++    LV+ I
Sbjct: 143 NKCDMEDERVISTERGQHLGEQLGFE-FFETSAKDNINVKQTFERLVDII 191


>gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]
          Length = 220

 Score =  115 bits (287), Expect = 4e-26
 Identities = 60/170 (35%), Positives = 102/170 (60%), Gaps = 6/170 (3%)

Query: 23  EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDI 82
           +++FK+L+IG   VGKTS + RY    F+  + +T+G+DF +K +  + +  ++LQ+WD 
Sbjct: 20  DYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKR-IKLQIWDT 78

Query: 83  AGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLA 142
           AGQER+  +T  YY+ A+G  +++DI+   +F AV  W + +  K +  + + +  +L+ 
Sbjct: 79  AGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQI--KTYSWDNAQV--LLVG 134

Query: 143 NKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKI 192
           NKCD   +   S  +  Q     GF  +FE SAKDNIN+++    LV+ I
Sbjct: 135 NKCDMEDERVVSSERGRQLADHLGFE-FFEASAKDNINVKQTFERLVDVI 183


>gi|21361884 RAB2B protein isoform 1 [Homo sapiens]
          Length = 216

 Score =  114 bits (286), Expect = 5e-26
 Identities = 67/190 (35%), Positives = 107/190 (56%), Gaps = 10/190 (5%)

Query: 21  TREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLW 80
           T  +LFK ++IG+ GVGK+ ++ ++  + F   +  TIGV+F  +++N D +  ++LQ+W
Sbjct: 2   TYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQ-IKLQIW 60

Query: 81  DIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVL 140
           D AGQE F ++TR YY+ A GA +V+DI+R  TF  +  W    D++ H  + S +  +L
Sbjct: 61  DTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLE--DARQH--SSSNMVIML 116

Query: 141 LANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEA----ARFLVEKILVNH 196
           + NK D          + + F +EHG   + ETSAK   N+EEA    A+ +  KI    
Sbjct: 117 IGNKSDLESRRDVKREEGEAFAREHGLI-FMETSAKTACNVEEAFINTAKEIYRKIQQGL 175

Query: 197 QSFPNEENDV 206
               NE N +
Sbjct: 176 FDVHNEANGI 185


>gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score =  114 bits (285), Expect = 7e-26
 Identities = 70/213 (32%), Positives = 122/213 (57%), Gaps = 16/213 (7%)

Query: 23  EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDI 82
           ++LFKV++IG+ GVGK++++ R+    F+   ++TIGV+FA + +  D +T ++ Q+WD 
Sbjct: 9   DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKT-IKAQIWDT 67

Query: 83  AGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLA 142
           AGQER+  +T  YY+ AVGA +V+DI++  T+E V +W  +L         S I  +L+ 
Sbjct: 68  AGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHA----DSNIVIMLVG 123

Query: 143 NKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKI--LVNHQSFP 200
           NK D     +    +   F +++  + + ETSA D+ N+EEA + ++ +I  +V+ +   
Sbjct: 124 NKSDLRHLRAVPTDEARAFAEKNNLS-FIETSALDSTNVEEAFKNILTEIYRIVSQKQIA 182

Query: 201 NEE-------NDVDKIKLDQET-LRAENKSQCC 225
           +         N+V  I +   T  +  NK QCC
Sbjct: 183 DRAAHDESPGNNVVDISVPPTTDGQKPNKLQCC 215


>gi|4758984 Ras-related protein Rab-11A [Homo sapiens]
          Length = 216

 Score =  114 bits (285), Expect = 7e-26
 Identities = 64/187 (34%), Positives = 111/187 (59%), Gaps = 9/187 (4%)

Query: 23  EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDI 82
           ++LFKV++IG+ GVGK++++ R+    F+   ++TIGV+FA + +  D +T ++ Q+WD 
Sbjct: 9   DYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKT-IKAQIWDT 67

Query: 83  AGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLA 142
           AGQER+  +T  YY+ AVGA +V+DI++  T+E V +W  +L         S I  +L+ 
Sbjct: 68  AGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHA----DSNIVIMLVG 123

Query: 143 NKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFL---VEKILVNHQSF 199
           NK D     +    +   F +++G + + ETSA D+ N+E A + +   + +I+   Q  
Sbjct: 124 NKSDLRHLRAVPTDEARAFAEKNGLS-FIETSALDSTNVEAAFQTILTEIYRIVSQKQMS 182

Query: 200 PNEENDV 206
              END+
Sbjct: 183 DRRENDM 189


>gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]
          Length = 212

 Score =  114 bits (284), Expect = 9e-26
 Identities = 66/187 (35%), Positives = 106/187 (56%), Gaps = 10/187 (5%)

Query: 24  HLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIA 83
           +LFK ++IG+ GVGK+ ++ ++  + F   +  TIGV+F  +++  D +  ++LQ+WD A
Sbjct: 5   YLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQ-IKLQIWDTA 63

Query: 84  GQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLAN 143
           GQE F ++TR YY+ A GA +V+DI+R  TF  +  W    D++ H  + S +  +L+ N
Sbjct: 64  GQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLE--DARQH--SNSNMVIMLIGN 119

Query: 144 KCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEA----ARFLVEKILVNHQSF 199
           K D          + + F +EHG   + ETSAK   N+EEA    A+ + EKI       
Sbjct: 120 KSDLESRREVKKEEGEAFAREHGLI-FMETSAKTASNVEEAFINTAKEIYEKIQEGVFDI 178

Query: 200 PNEENDV 206
            NE N +
Sbjct: 179 NNEANGI 185


>gi|19923483 GTPase Rab14 [Homo sapiens]
          Length = 215

 Score =  113 bits (282), Expect = 1e-25
 Identities = 63/182 (34%), Positives = 104/182 (57%), Gaps = 6/182 (3%)

Query: 16  APAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLV 75
           A AP    ++FK ++IG++GVGK+ ++ ++  + F      TIGV+F  +++    +  +
Sbjct: 2   ATAPYNYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQK-I 60

Query: 76  RLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSP 135
           +LQ+WD AGQERF  +TR YY+ A GA +V+DI+R ST+  +  W +D     +L N + 
Sbjct: 61  KLQIWDTAGQERFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDAR---NLTNPNT 117

Query: 136 IPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVN 195
           +  +L+ NK D       +  +  QF +E+G   + E SAK   N+E+A     +KI  N
Sbjct: 118 V-IILIGNKADLEAQRDVTYEEAKQFAEENGLL-FLEASAKTGENVEDAFLEAAKKIYQN 175

Query: 196 HQ 197
            Q
Sbjct: 176 IQ 177


>gi|82659107 ras-related GTP-binding protein 4b [Homo sapiens]
          Length = 213

 Score =  111 bits (278), Expect = 4e-25
 Identities = 67/177 (37%), Positives = 104/177 (58%), Gaps = 10/177 (5%)

Query: 20  ETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQL 79
           ET + LFK LVIG  G GK+ ++ +++   F Q    TIGV+F  +V+N   +T V+LQ+
Sbjct: 3   ETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKT-VKLQI 61

Query: 80  WDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAV 139
           WD AGQERF ++TR YY+ A GA +V+DI+   T+ ++  W +D  + +  PN   I  +
Sbjct: 62  WDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDART-LASPN---IVVI 117

Query: 140 LLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEA----ARFLVEKI 192
           L  NK D + +   +  +  +F +E+    + ETSA    N+EEA    AR ++ KI
Sbjct: 118 LCGNKKDLDPEREVTFLEASRFAQENELM-FLETSALTGENVEEAFLKCARTILNKI 173


>gi|19923750 RAB3B, member RAS oncogene family [Homo sapiens]
          Length = 219

 Score =  111 bits (277), Expect = 6e-25
 Identities = 59/170 (34%), Positives = 102/170 (60%), Gaps = 6/170 (3%)

Query: 23  EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDI 82
           +++FK+L+IG   VGKTS + RY    F+  + +T+G+DF +K + +     V+LQ+WD 
Sbjct: 20  DYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTV-YRHEKRVKLQIWDT 78

Query: 83  AGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAVLLA 142
           AGQER+  +T  YY+ A+G  +++DI+   +F AV  W + +  K +  + + +  +L+ 
Sbjct: 79  AGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQI--KTYSWDNAQV--ILVG 134

Query: 143 NKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKI 192
           NKCD  ++    P++  Q   E     +FE SAK+NI++ +A   LV+ I
Sbjct: 135 NKCDM-EEERVVPTEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAI 183


>gi|19923260 RAB4A, member RAS oncogene family [Homo sapiens]
          Length = 218

 Score =  111 bits (277), Expect = 6e-25
 Identities = 68/197 (34%), Positives = 105/197 (53%), Gaps = 16/197 (8%)

Query: 20  ETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQL 79
           ET + LFK LVIG  G GK+ ++ +++ + F      TIGV+F  K++N   +  V+LQ+
Sbjct: 8   ETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGK-YVKLQI 66

Query: 80  WDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDLDSKVHLPNGSPIPAV 139
           WD AGQERF ++TR YY+ A GA +V+DI+   T+ A+  W +D      +     I  +
Sbjct: 67  WDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTD----ARMLASQNIVII 122

Query: 140 LLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEAARFLVEKILVNHQSF 199
           L  NK D + D   +  +  +F +E+    + ETSA    N+EEA      KIL      
Sbjct: 123 LCGNKKDLDADREVTFLEASRFAQENELM-FLETSALTGENVEEAFVQCARKIL------ 175

Query: 200 PNEENDVDKIKLDQETL 216
               N ++  +LD E +
Sbjct: 176 ----NKIESGELDPERM 188


>gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]
          Length = 219

 Score =  111 bits (277), Expect = 6e-25
 Identities = 66/188 (35%), Positives = 108/188 (57%), Gaps = 9/188 (4%)

Query: 6   AGDPGLGAAAAPAPETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALK 65
           AGD   G   A A +  +++FK+L+IG   VGKTS + RY    F+  + +T+G+DF +K
Sbjct: 4   AGDTQAGPRDA-ADQNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVK 62

Query: 66  -VLNWDSRTLVRLQLWDIAGQERFGNMTRVYYKEAVGAFVVFDISRSSTFEAVLKWKSDL 124
            V   D R  ++LQ+WD AGQER+  +T  YY+ A+G  +++DI+   +F AV  W + +
Sbjct: 63  TVYRHDKR--IKLQIWDTAGQERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQI 120

Query: 125 DSKVHLPNGSPIPAVLLANKCDQNKDSSQSPSQVDQFCKEHGFAGWFETSAKDNINIEEA 184
             K +  + + +  +L+ NKCD   +         +   + GF  +FE SAK+NIN+++ 
Sbjct: 121 --KTYSWDNAQV--ILVGNKCDLEDERVVPAEDGRRLADDLGFE-FFEASAKENINVKQV 175

Query: 185 ARFLVEKI 192
              LV+ I
Sbjct: 176 FERLVDVI 183


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,499,422
Number of Sequences: 37866
Number of extensions: 358359
Number of successful extensions: 2063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 181
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 1626
Number of HSP's gapped (non-prelim): 267
length of query: 225
length of database: 18,247,518
effective HSP length: 99
effective length of query: 126
effective length of database: 14,498,784
effective search space: 1826846784
effective search space used: 1826846784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.