BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|57232746 nuclear receptor interacting protein 1 [Homo sapiens] (1158 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|57232746 nuclear receptor interacting protein 1 [Homo sapiens] 2294 0.0 gi|171184451 centrosome-associated protein 350 [Homo sapiens] 47 8e-05 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 43 0.002 gi|161016767 mucin 21 [Homo sapiens] 43 0.002 gi|217330641 IWS1 homolog [Homo sapiens] 43 0.002 gi|120953251 neuron navigator 3 [Homo sapiens] 42 0.003 gi|163838629 retinoblastoma-associated protein 140 isoform b [Ho... 42 0.003 gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 42 0.003 gi|164420691 homeodomain interacting protein kinase 2 isoform 2 ... 39 0.022 gi|164420685 homeodomain interacting protein kinase 2 isoform 1 ... 39 0.022 gi|189011568 adenomatous polyposis coli [Homo sapiens] 39 0.022 gi|189011566 adenomatous polyposis coli [Homo sapiens] 39 0.022 gi|53759122 adenomatous polyposis coli [Homo sapiens] 39 0.022 gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] 39 0.029 gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 39 0.029 gi|34577118 dopey family member 1 [Homo sapiens] 39 0.029 gi|112734859 zinc finger protein 654 [Homo sapiens] 38 0.049 gi|154350236 hypothetical protein LOC56204 [Homo sapiens] 38 0.064 gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] 37 0.083 gi|206725422 G protein-coupled receptor kinase interacting ArfGA... 37 0.083 gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 37 0.11 gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 37 0.11 gi|149944526 additional sex combs like 3 [Homo sapiens] 37 0.11 gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 37 0.14 gi|196114970 protein tyrosine phosphatase, non-receptor type 12 ... 37 0.14 gi|196114967 protein tyrosine phosphatase, non-receptor type 12 ... 37 0.14 gi|196114951 protein tyrosine phosphatase, non-receptor type 12 ... 37 0.14 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 36 0.19 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 36 0.19 gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens] 36 0.19 >gi|57232746 nuclear receptor interacting protein 1 [Homo sapiens] Length = 1158 Score = 2294 bits (5944), Expect = 0.0 Identities = 1158/1158 (100%), Positives = 1158/1158 (100%) Query: 1 MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHNEEDQNFNISGSAFPT 60 MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHNEEDQNFNISGSAFPT Sbjct: 1 MTHGEELGSDVHQDSIVLTYLEGLLMHQAAGGSGTAVDKKSAGHNEEDQNFNISGSAFPT 60 Query: 61 CQSNGPVLNTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIMNLNVKKEALLAGMV 120 CQSNGPVLNTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIMNLNVKKEALLAGMV Sbjct: 61 CQSNGPVLNTHTYQGSGMLHLKKARLLQSSEDWNAAKRKRLSDSIMNLNVKKEALLAGMV 120 Query: 121 DSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHDSLKVEKDLRCYGV 180 DSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHDSLKVEKDLRCYGV Sbjct: 121 DSVPKGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHDSLKVEKDLRCYGV 180 Query: 181 ASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRDRFAESPHHVGQSGTKVMSEPLSCAARL 240 ASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRDRFAESPHHVGQSGTKVMSEPLSCAARL Sbjct: 181 ASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRDRFAESPHHVGQSGTKVMSEPLSCAARL 240 Query: 241 QAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAA 300 QAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAA Sbjct: 241 QAVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAA 300 Query: 301 MARLQENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNA 360 MARLQENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNA Sbjct: 301 MARLQENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNA 360 Query: 361 GYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDN 420 GYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDN Sbjct: 361 GYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDN 420 Query: 421 NPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDI 480 NPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDI Sbjct: 421 NPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDI 480 Query: 481 KEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVI 540 KEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVI Sbjct: 481 KEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVI 540 Query: 541 ESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSM 600 ESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSM Sbjct: 541 ESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSM 600 Query: 601 DLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTD 660 DLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTD Sbjct: 601 DLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTD 660 Query: 661 KPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSEIENLLERRTVLQLLLGNP 720 KPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSEIENLLERRTVLQLLLGNP Sbjct: 661 KPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSEIENLLERRTVLQLLLGNP 720 Query: 721 NKGKSEKKEKTPLRDESTQEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAKSAP 780 NKGKSEKKEKTPLRDESTQEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAKSAP Sbjct: 721 NKGKSEKKEKTPLRDESTQEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAKSAP 780 Query: 781 FLGMAPAVQRSAPALPVSEDFKSEPVSPQDFSFSKNGLLSRLLRQNQDSYLADDSDRSHR 840 FLGMAPAVQRSAPALPVSEDFKSEPVSPQDFSFSKNGLLSRLLRQNQDSYLADDSDRSHR Sbjct: 781 FLGMAPAVQRSAPALPVSEDFKSEPVSPQDFSFSKNGLLSRLLRQNQDSYLADDSDRSHR 840 Query: 841 NNEMALLESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAANNHSAPEVLYGSLLNQEEL 900 NNEMALLESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAANNHSAPEVLYGSLLNQEEL Sbjct: 841 NNEMALLESKNLCMVPKKRKLYTEPLENPFKKMKNNIVDAANNHSAPEVLYGSLLNQEEL 900 Query: 901 KFSRNDLEFKYPAGHGSASESEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVADS 960 KFSRNDLEFKYPAGHGSASESEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVADS Sbjct: 901 KFSRNDLEFKYPAGHGSASESEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVADS 960 Query: 961 KKKGHKNNVTNSKPEFSISSLNGLMYSSTQPSSCMDNRTFSYPGVVKTPVSPTFPEHLGC 1020 KKKGHKNNVTNSKPEFSISSLNGLMYSSTQPSSCMDNRTFSYPGVVKTPVSPTFPEHLGC Sbjct: 961 KKKGHKNNVTNSKPEFSISSLNGLMYSSTQPSSCMDNRTFSYPGVVKTPVSPTFPEHLGC 1020 Query: 1021 AGSRPESGLLNGCSMPSEKGPIKWVITDAEKNEYEKDSPRLTKTNPILYYMLQKGGNSVT 1080 AGSRPESGLLNGCSMPSEKGPIKWVITDAEKNEYEKDSPRLTKTNPILYYMLQKGGNSVT Sbjct: 1021 AGSRPESGLLNGCSMPSEKGPIKWVITDAEKNEYEKDSPRLTKTNPILYYMLQKGGNSVT 1080 Query: 1081 SRETQDKDIWREASSAESVSQVTAKEELLPTAETKASFFNLRSPYNSHMGNNASRPHSAN 1140 SRETQDKDIWREASSAESVSQVTAKEELLPTAETKASFFNLRSPYNSHMGNNASRPHSAN Sbjct: 1081 SRETQDKDIWREASSAESVSQVTAKEELLPTAETKASFFNLRSPYNSHMGNNASRPHSAN 1140 Query: 1141 GEVYGLLGSVLTIKKESE 1158 GEVYGLLGSVLTIKKESE Sbjct: 1141 GEVYGLLGSVLTIKKESE 1158 >gi|171184451 centrosome-associated protein 350 [Homo sapiens] Length = 3117 Score = 47.4 bits (111), Expect = 8e-05 Identities = 71/322 (22%), Positives = 121/322 (37%), Gaps = 48/322 (14%) Query: 472 DPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQL---LLGHKNEENVEKNTS-----PQGVH 523 DP++ DV + Q S+ S+ S + + +L L +K EEN N +G+ Sbjct: 474 DPRL-DVLHRHLQRNSERSRSKSRSENNIKKLASSLPDNKQEENTALNKDFLPIEIRGIL 532 Query: 524 NDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYV 583 +D+ +T + A+ +E + + PV P ++ SP+ + N P V Sbjct: 533 DDLQLDSTAHTAKQDTVELQNQKSSAPVHAP------RSHSPVKRKPDKITA--NEDPPV 584 Query: 584 CSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSM 643 S + T+ + + + ++ K + + AQ AT +K LQ L + ++ Sbjct: 585 ISKRRHYDTDEVRQY---IVRQQEERKRKQNEEKKAQKEATEQKNKRLQELYRKQKEAFT 641 Query: 644 SVEEQRPSKQLLTGNTDKPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSEI 703 V+ PS+ T + S LL KT E + +Q T +PG S Sbjct: 642 KVKNVPPSEPSATRR-------LQETYSKLLLEKTLLEEPSHQHVTQETQAKPGYQPS-- 692 Query: 704 ENLLERRTVLQLLLGNPNKGKSEKKEKTPLRDESTQEHSERALSEQILMVKIKSEPCDDL 763 G+S+K+ K R S S+ +LSE + K Sbjct: 693 -------------------GESDKENKVQERPPSASSSSDMSLSEPPQPLARKDLMESTW 733 Query: 764 QIPNTNVHLSHDAKSAPFLGMA 785 P H ++ PF G A Sbjct: 734 MQPERLSPQVHHSQPQPFAGTA 755 Score = 33.5 bits (75), Expect = 1.2 Identities = 44/221 (19%), Positives = 94/221 (42%), Gaps = 18/221 (8%) Query: 361 GYKNSLERNNIKQAANNSLLLHL----LKSQTIPKPMNGHSHSERGSIFEESSTPTTIDE 416 G+++ L+R N+ L + + P G S +E+ S E ST + ++ Sbjct: 1079 GFEDKLDRGTSTSRPLNATATPLSGVSYEDDFVSSPGTGTS-TEKKSTLEPHSTLSPQED 1137 Query: 417 YSDN----NPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNT-W 471 +S+ +PS D +S S + S + +K + ++ LD+FT ++ N+ Sbjct: 1138 HSNRKSAYDPSSVDVTSQHSSGAQSAASSRSSTSSKGKKGKKEKTEWLDSFTGNVQNSLL 1197 Query: 472 DPKVPDVDIKEDQDTSKNSKLN------SHQKVTLLQLLLGHKNEENVEKNTSPQGVHND 525 D + + + + + +SKL+ + + L+ L GH + +K S + + Sbjct: 1198 DEEKAERGSHQGKKSGTSSKLSVKDFEQTLDTDSTLEDLSGHSVSVSSDKGRSQKTPTSP 1257 Query: 526 VSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPI 566 +S + ++ + S+ R+ PP +T K +P+ Sbjct: 1258 LSPSSQKSLQFD--VAGTSSERSKSSVMPPTITGFKPNAPL 1296 Score = 32.0 bits (71), Expect = 3.5 Identities = 44/171 (25%), Positives = 68/171 (39%), Gaps = 13/171 (7%) Query: 704 ENLLERRTVLQLLLGNPN--KGKSEKKEK-TPLRDESTQEH----SERALSEQILMVKIK 756 E +L+ R Q + +PN GK ++K T +D S EH E SE + K Sbjct: 2326 EEMLKERQSDQDMNHSPNIQSGKDIHEQKNTKEKDLSWSEHLFAPKEIPYSEDFEVSSFK 2385 Query: 757 SEPC-----DDLQIPNTNVHLSHDAKSAPFLGMAPAVQRSAPALPVSEDFKSEPVSPQDF 811 E DD ++ + + L D++S S S + SE +S + Sbjct: 2386 KEISAELYKDDFEVSSL-LSLRKDSQSCRDKPQPMRSSTSGATSFGSNEEISECLSEKSL 2444 Query: 812 SFSKNGLLSRLLRQNQDSYLADDSDRSHRNNEMALLESKNLCMVPKKRKLY 862 S N RLL + L +RS +E + ES +L VP +L+ Sbjct: 2445 SIHSNVHSDRLLELKSPTELMKSKERSDVEHEQQVTESPSLASVPTADELF 2495 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 43.1 bits (100), Expect = 0.002 Identities = 78/450 (17%), Positives = 165/450 (36%), Gaps = 35/450 (7%) Query: 394 NGHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSE 453 NG+ +++ + S + D +N S + DSS +SS SN ++ S+ Sbjct: 532 NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN-------SSSDSDSSD 584 Query: 454 SDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENV 513 SD S D+ + N+ D D + D+S +S S + ++ Sbjct: 585 SDSSDSSDSDSSDSSNSSDSS-DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSS 643 Query: 514 EKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSL 573 + N+S ++D S + + + S S S++ ++ + SS + N S+ S Sbjct: 644 DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSD 703 Query: 574 VIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQN 633 + S+ S +N++ + S + + S D + + ++++ S+ + Sbjct: 704 SSDSSDSDSSDSSDSSN-SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762 Query: 634 LAQCGMQSSMSVEEQRPSKQLLTGNTDKPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTG 693 + SS S + S + ++ D NS SN +++ + + + S + Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822 Query: 694 PEPGLSGSEIENLLERRTVLQLLLGNPNKGKSEKKEKTPLRDESTQEHSERALSEQILMV 753 + S+ + + S+ + + D S + S R+ S Sbjct: 823 SSDSSNSSD---------------SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN---- 863 Query: 754 KIKSEPCDDLQIPNTNVHLSHDAKSAPFLGMAPAVQRSAPALPVSEDFKSEPVSPQDFSF 813 S+ D N S D+ + + S+ + S+ S+ + D S Sbjct: 864 --SSDSSDSSDSSN-----SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916 Query: 814 SKNGLLSRLLRQNQDSYLADDSDRSHRNNE 843 S N S + D+ + DS S +++ Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946 Score = 39.7 bits (91), Expect = 0.017 Identities = 71/398 (17%), Positives = 142/398 (35%), Gaps = 22/398 (5%) Query: 322 SSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYKNSLERNNIKQAANNSLLL 381 SS+ + + +S S + S ++ ++ S ++ K+ +N +++NS Sbjct: 598 SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS 657 Query: 382 HLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPI 441 S + S+ S + S++ + D +N S + DSS S S+ Sbjct: 658 DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS---- 713 Query: 442 DLSCKHRTEKSESDQPVSLD-----------------NFTQSLLNTWDPKVPDVDIKEDQ 484 D S + S+SD S D N + S ++ D D Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773 Query: 485 DTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPS 544 S +S +S + + + N+S +D S ++ N + +S S Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833 Query: 545 TNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTK 604 + + S+ +S + S + S +S S S+ ++ SN S + + Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893 Query: 605 SKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTDKPIG 664 S D + + + NS+ S S + ++ S S + + ++D Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS-N 952 Query: 665 MIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSE 702 D NS SN +++ + N + SS + S+ Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 43.1 bits (100), Expect = 0.002 Identities = 86/402 (21%), Positives = 139/402 (34%), Gaps = 34/402 (8%) Query: 311 DVGSYQLPKGMSSHLN-GQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYKNSLERN 369 + GS + G S+ N G + TSS A+ S ++V N + I+ +S + Sbjct: 32 NTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTAT 91 Query: 370 NIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSS 429 N + + +S + S++ + + ESSTP++ + N+ S T S Sbjct: 92 NSEFSTVSSGISIATNSESSTTSSGASTATN-----SESSTPSSGASTATNSDSSTTSSG 146 Query: 430 GDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSK- 488 ++ S+ T S T S +T + E TS Sbjct: 147 ASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSG 206 Query: 489 -NSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNR 547 ++ NS + T G N E +T+ G + A S +PS+ Sbjct: 207 ASTATNSESRTT----SNGAGTATNSESSTTSSGA----------STATNSESSTPSSGA 252 Query: 548 TTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLT-----NTASNHSMDL 602 T ++ TSS AG+ N S+ S V S T SE T NTA+N Sbjct: 253 GTATNSESSTTSSGAGTATN-SESSTV----SSGISTVTNSESSTPSSGANTATNSESST 307 Query: 603 TKS--KDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTD 660 T S + ++AT S S + A S S S +G++ Sbjct: 308 TSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSST 367 Query: 661 KPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSE 702 G NS + + A + SS + + SE Sbjct: 368 TSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSE 409 Score = 30.8 bits (68), Expect = 7.8 Identities = 38/211 (18%), Positives = 84/211 (39%), Gaps = 7/211 (3%) Query: 244 ASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMAR 303 +S A AT+ + S S ++ + +SE+ A ++++ ++ A + Sbjct: 260 SSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNS- 318 Query: 304 LQENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYK 363 ++ G+ SS + A T+++ ++ SS G +S + Sbjct: 319 --DSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTAT 376 Query: 364 NSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNPS 423 NS E + + A+ + +S T + ++SE ++ +ST T + + ++ + Sbjct: 377 NS-ESSTVSSGASTATTS---ESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGA 432 Query: 424 FTDDSSGDESSYSNCVPIDLSCKHRTEKSES 454 T +SG + + L+ H T S S Sbjct: 433 NTATNSGSSVTSAGSGTAALTGMHTTSHSAS 463 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 42.7 bits (99), Expect = 0.002 Identities = 114/630 (18%), Positives = 237/630 (37%), Gaps = 75/630 (11%) Query: 396 HSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESD 455 HS S+ GS+ S T+ E DS DE N + HR + S+S+ Sbjct: 37 HSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSE 96 Query: 456 QPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEK 515 + P E++D +++ +S + T +NEE + Sbjct: 97 SEERAE--------------PPASDSENEDVNQHGS-DSESEETRKLPGSDSENEELLNG 141 Query: 516 NTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVI 575 + S + DV K + + +SP+++ T + P ++ S++ P Sbjct: 142 HAS-DSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSEN 200 Query: 576 KWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLA 635 + P + ++SE+L + S +S++PP + + +E + + ++ Sbjct: 201 EEPPKPRMSDSESEELPKPQVSDS----ESEEPPRHQASDSENEELPKPRISDSESEDPP 256 Query: 636 QCGMQSSMSVEEQRPSKQLLTGNTDKPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPE 695 + Q+S S E+ P ++ ++ P + ++ + + + S+ GP+ Sbjct: 257 R--HQASDSENEELPKPRISDSESEDP------PRNQASDSENEELPKPRVSDSESEGPQ 308 Query: 696 PG-LSGSEIENLLERRTVLQLLLGNPNKGKSEKKEKTPLRDESTQEHSERALSEQILMVK 754 G S SE E+ + Q + + + K E T ++++S HS+ + + K Sbjct: 309 KGPASDSETEDASRHK---QKPESDDDSDRENKGEDTEMQNDSF--HSDSHMDRK----K 359 Query: 755 IKSEPCDDLQIPNTNVHLSHDAKSAPFLGMAPAVQRSAPALPVSED------FKSEPVSP 808 S ++ + + D K +A +R A L SED KS VS Sbjct: 360 FHSSDSEEEEHKKQKMDSDEDEKEGEEEKVA---KRKAAVLSDSEDEEKASAKKSRVVSD 416 Query: 809 QDFSFSKNGLLSRLLRQNQDSYLADDSDRSHRNNEMALLESKNLCMVPKKRKLYTEPLEN 868 D S S +S + + + +D + + + L + KN +++ L+ E+ Sbjct: 417 ADDSDS--DAVSDKSGKREKTIASDSEEEAGKE----LSDKKN-----EEKDLFGSDSES 465 Query: 869 PFKKMKNNIVDAANNHSAPEVLYGSLLNQEELKFSRNDLEFKYPAGHGSASESEHRSWAR 928 + +N I D E + NQE+L+ + + + K A +S+ + Sbjct: 466 G-NEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQVK------EAEDSDSDDNIK 518 Query: 929 ESKSFNVLKQLLLSENCVRDLSPHRSNSVADSKKKGHKNNVTNSKPEFSISSLNGLMYSS 988 K + L ++ R S++ +++ S + +S++ M + Sbjct: 519 RGKHMDFLSDF--------EMMLQRKKSMSGKRRRNRDGGTFISDADDVVSAMIVKMNEA 570 Query: 989 TQPSSCMDNRTFSYPGVVKTPVSPTFPEHL 1018 + ++N+ P + K + P HL Sbjct: 571 AEEDRQLNNQ--KKPALKKLTLLPAVVMHL 598 >gi|120953251 neuron navigator 3 [Homo sapiens] Length = 2363 Score = 42.4 bits (98), Expect = 0.003 Identities = 125/557 (22%), Positives = 206/557 (36%), Gaps = 70/557 (12%) Query: 160 QGYALSHDSLKVEKDLRCYGVASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRDRFAESP 219 QG A + K+ D + +A S K L+K + +D L ++ + +I + E Sbjct: 71 QGKAKEKEDSKIYTDWANHYLAKSGHKRLIKDLQ-QDIADGVLLAEIIQ-IIANEKVEDI 128 Query: 220 HHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLS----SEAH 275 + +S ++++ C + L A V+ ++ A L LS + H Sbjct: 129 NGCPRSQSQMIENVDVCLSFLAARGVNVQGLSAEEIRNGNLKAILGLFFSLSRYKQQQHH 188 Query: 276 LQQYSRE---------HALKTQNANQAASER-----LAAMARLQENGQKDVGSYQLPKGM 321 QQY + HA A+QA +++ LAA Q N S + P + Sbjct: 189 QQQYYQSLVELQQRVTHASPPSEASQAKTQQDMQSSLAARYATQSNHSGIATSQKKPTRL 248 Query: 322 SSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYKNSLERNNIKQAANNSLL- 380 A SSSK+ + + Q+ I + P N Y N E+++ K ++S + Sbjct: 249 PGPSRVPAAGSSSKVQGASNLNRRSQSFNSIDKNKPPN--YANGNEKDSSKGPQSSSGVN 306 Query: 381 -------------LHLLKSQTIPKPMNGHS----HSERGSIF--EESSTPTTIDEYSDN- 420 + S + KP S HS ++ ++SST T+ SD Sbjct: 307 GNVQPPSTAGQPPASAIPSPSASKPWRSKSMNVKHSATSTMLTVKQSSTATSPTPSSDRL 366 Query: 421 NPSFTDD----SSGDESSYSNCVPIDLSCKHRTEKSESDQPVSL----DNFTQSL----- 467 P ++ SG +S ++ R + S P D F++S Sbjct: 367 KPPVSEGVKTAPSGQKSMLEKFKLVNARTALRPPQPPSSGPSDGGKDDDAFSESGEMEGF 426 Query: 468 ---LNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNT--SPQGV 522 LN+ + K N K +LLQ K E+N +KN + + V Sbjct: 427 NSGLNSGGSTNSSPKVSPKLAPPKAGSKNLSNKKSLLQPK--EKEEKNRDKNKVCTEKPV 484 Query: 523 HNDVSKFNTQNYARTSVIES--PSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSP 580 + + +TS I S P ++TT L+ SS +G P S+ V + SP Sbjct: 485 KEEKDQVTEMAPKKTSKIASLIPKGSKTTAAKKESLIPSS-SGIPKPGSKVPTVKQTISP 543 Query: 581 PYVCSTQSEKLTNTASNHSMDLTK----SKDPPGEKPAQNEGAQNSATFSASKLLQNLAQ 636 S +SEK T + S L+K K PA EG + + +AQ Sbjct: 544 GSTASKESEKFRTTKGSPSQSLSKPITMEKASASSCPAPLEGREAGQASPSGSCTMTVAQ 603 Query: 637 CGMQSSMSVEEQRPSKQ 653 QS+ + Q P +Q Sbjct: 604 SSGQSTGNGAVQLPQQQ 620 >gi|163838629 retinoblastoma-associated protein 140 isoform b [Homo sapiens] Length = 1233 Score = 42.4 bits (98), Expect = 0.003 Identities = 79/383 (20%), Positives = 144/383 (37%), Gaps = 48/383 (12%) Query: 125 KGKQDSTLLASLLQSFSSRLQTVALSQQIRQSLKEQGYALSHDSLKVEKDLRCYGVASSH 184 KG Q L +S + T + + LKE +S ++ E C V H Sbjct: 443 KGTQSLLLEVDATSKYSVAISTSEVGTDHKLHLKEDPNLISVNNF--EDCSLCPSVPIEH 500 Query: 185 --LKTLLKKSKVKDQKPDTNLPDVTKNLIRDRFAESPH-HVGQSGTKVMSEPLSCAARLQ 241 + K + V++ + L +T R SP +G+ G K + L Sbjct: 501 GFRRQQSKSNNVEETEIHWKLIPITGGNAR-----SPEDQLGKHGEKQTPDTLKGTTEDD 555 Query: 242 AVASMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAAS------ 295 + VE++ PA +P + E +L E LK +N + ++ Sbjct: 556 VLTGQVEEQCVPAAEAEPPAVSETTERTVLGEYNLFSRKIEEILKQKNVSYVSTVSTPIF 615 Query: 296 ---ERLAAMARLQENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGI 352 E++ ++ + G + G+ LN + K+SA P Sbjct: 616 STQEKMKRLSEFIYSKTSKAGVQEFVDGLHEKLN---------TIIIKASAKGGNLP--- 663 Query: 353 IPSSPKNAGYK---NSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESS 409 P SP ++G K N LER+ I ++++ HLL+ P+ + S +E Sbjct: 664 -PVSPNDSGAKIASNPLERHVIPVSSSDFNNKHLLE------PLCSDPLKDTNS--DEQH 714 Query: 410 TPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCK--HRTEKSESDQPVSLDNFTQSL 467 + + + E N P + + + VP D++ + T KS SD +S + Sbjct: 715 STSALTEVEMNQPQHATELM---VTSDHIVPGDMAREPVEETTKSPSDVNISAQPALSNF 771 Query: 468 LNTWDPKVPDVDIKEDQDTSKNS 490 ++ +P+V + +K +D KN+ Sbjct: 772 ISQLEPEVFNSLVKIMKDVQKNT 794 >gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo sapiens] Length = 2168 Score = 42.0 bits (97), Expect = 0.003 Identities = 88/439 (20%), Positives = 158/439 (35%), Gaps = 47/439 (10%) Query: 102 SDSIMNLNVKKEALLAGMVDSVPKGK------QDSTLLASLLQSFSSRLQTVALSQQIRQ 155 S+S + LL G+ D G+ Q+ + L + S+ + Q+ Q Sbjct: 289 SESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQ 348 Query: 156 SLKEQGYALSHDSLKVEKDLRCYGVASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRDRF 215 L +Q + S E+ + + H + V + KP + + K Sbjct: 349 VLSQQLPFIFQSSQAKEESV------NKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLI 402 Query: 216 AESPHHVGQSGTKVMSEPLSCAAR---------LQAVASMVEKRASPATSPKPSVACSQL 266 SP V ++G K SE S QA S ++K+ S + K A S Sbjct: 403 VPSPD-VLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQESSKSLKKVIAALSNP 461 Query: 267 ALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARLQENGQKDVGSYQLPKGMSSHLN 326 SS AH +Q L+ + N + L + Q NG + P +++ Sbjct: 462 KATSSSPAHPKQ-----TLENNHPNPFLTNAL--LGNHQPNGVIQSVIQEAPLALTTKTK 514 Query: 327 GQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYKNSLERNNIKQAANNSLLLH---- 382 Q++ + + + +S+T F +P+ + S + G N + S +LH Sbjct: 515 MQSKINEN---IAAASSTPFSSPVNLSTSGRRTPG-------NQTPVMPSASPILHSQGK 564 Query: 383 --LLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVP 440 + + P HSH + + + T + I D+ S D+ DE Sbjct: 565 EKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDE 624 Query: 441 IDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTL 500 D S ++E S+S+ + + + D D D + ++ + K +K S K Sbjct: 625 DDESDDSQSE-SDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPS 683 Query: 501 LQLLLGHKNEENVEKNTSP 519 + L GH N+ +P Sbjct: 684 MS-LTGHSTPRNLHIAKAP 701 >gi|164420691 homeodomain interacting protein kinase 2 isoform 2 [Homo sapiens] Length = 1171 Score = 39.3 bits (90), Expect = 0.022 Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 11/141 (7%) Query: 477 DVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGV-----HNDVSKFNT 531 D D +E+Q + S ++ +K + + + + NTSP V HN+ + F+T Sbjct: 866 DTDEEEEQKHAPTSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRAGHNNANAFDT 925 Query: 532 QNYARTSVIESPSTNRTTPVST--PPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSE 589 + +P T P+ T +L + P+N S HS K S V ST Sbjct: 926 KGSLENHCTGNPRTIIVPPLKTQASEVLVECDSLVPVNTSHHSSSYKSKSSSNVTSTSG- 984 Query: 590 KLTNTASNHSMDLTKSKDPPG 610 +++ + S +T + PG Sbjct: 985 ---HSSGSSSGAITYRQQRPG 1002 >gi|164420685 homeodomain interacting protein kinase 2 isoform 1 [Homo sapiens] Length = 1198 Score = 39.3 bits (90), Expect = 0.022 Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 11/141 (7%) Query: 477 DVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGV-----HNDVSKFNT 531 D D +E+Q + S ++ +K + + + + NTSP V HN+ + F+T Sbjct: 893 DTDEEEEQKHAPTSTVSKQRKNVISCVTVHDSPYSDSSSNTSPYSVQQRAGHNNANAFDT 952 Query: 532 QNYARTSVIESPSTNRTTPVST--PPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSE 589 + +P T P+ T +L + P+N S HS K S V ST Sbjct: 953 KGSLENHCTGNPRTIIVPPLKTQASEVLVECDSLVPVNTSHHSSSYKSKSSSNVTSTSG- 1011 Query: 590 KLTNTASNHSMDLTKSKDPPG 610 +++ + S +T + PG Sbjct: 1012 ---HSSGSSSGAITYRQQRPG 1029 >gi|189011568 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 39.3 bits (90), Expect = 0.022 Identities = 68/386 (17%), Positives = 142/386 (36%), Gaps = 17/386 (4%) Query: 245 SMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARL 304 S + + +SP+T+ S +++ QQ + ++NA+ A+ Sbjct: 2343 SQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLN 2402 Query: 305 Q-ENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYK 363 Q NG +L + S+ +G S + + + S + + P + + + Sbjct: 2403 QMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASF 2462 Query: 364 NSLERNNIKQAANNSLLLHLLKSQTIPK-PMNGHSHSERGSIFEESSTPTTIDEYSDNNP 422 SL ++ + S + S ++P ++ HS + G + + EY+D P Sbjct: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522 Query: 423 SFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDI-K 481 + D + S + +PI+ S + E S+ + ++TW I Sbjct: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSL-------PRVSTWRRTGSSSSILS 2575 Query: 482 EDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIE 541 ++S+ +K + V + K + K T + N+ S N+ + +S Sbjct: 2576 ASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGAT 2635 Query: 542 SPSTNRTTPVSTPPLLTSSK------AGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTA 595 + + ++T P ++ ++ PIN + N+PP + S SEK Sbjct: 2636 NGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV-SEKANPNI 2694 Query: 596 SNHSMDLTKSKDPPGEKPAQNEGAQN 621 + + K G P + G +N Sbjct: 2695 KDSKDNQAKQNVGNGSVPMRTVGLEN 2720 >gi|189011566 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 39.3 bits (90), Expect = 0.022 Identities = 68/386 (17%), Positives = 142/386 (36%), Gaps = 17/386 (4%) Query: 245 SMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARL 304 S + + +SP+T+ S +++ QQ + ++NA+ A+ Sbjct: 2343 SQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLN 2402 Query: 305 Q-ENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYK 363 Q NG +L + S+ +G S + + + S + + P + + + Sbjct: 2403 QMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASF 2462 Query: 364 NSLERNNIKQAANNSLLLHLLKSQTIPK-PMNGHSHSERGSIFEESSTPTTIDEYSDNNP 422 SL ++ + S + S ++P ++ HS + G + + EY+D P Sbjct: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522 Query: 423 SFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDI-K 481 + D + S + +PI+ S + E S+ + ++TW I Sbjct: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSL-------PRVSTWRRTGSSSSILS 2575 Query: 482 EDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIE 541 ++S+ +K + V + K + K T + N+ S N+ + +S Sbjct: 2576 ASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGAT 2635 Query: 542 SPSTNRTTPVSTPPLLTSSK------AGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTA 595 + + ++T P ++ ++ PIN + N+PP + S SEK Sbjct: 2636 NGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV-SEKANPNI 2694 Query: 596 SNHSMDLTKSKDPPGEKPAQNEGAQN 621 + + K G P + G +N Sbjct: 2695 KDSKDNQAKQNVGNGSVPMRTVGLEN 2720 >gi|53759122 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 39.3 bits (90), Expect = 0.022 Identities = 68/386 (17%), Positives = 142/386 (36%), Gaps = 17/386 (4%) Query: 245 SMVEKRASPATSPKPSVACSQLALLLSSEAHLQQYSREHALKTQNANQAASERLAAMARL 304 S + + +SP+T+ S +++ QQ + ++NA+ A+ Sbjct: 2343 SQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLN 2402 Query: 305 Q-ENGQKDVGSYQLPKGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYK 363 Q NG +L + S+ +G S + + + S + + P + + + Sbjct: 2403 QMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASF 2462 Query: 364 NSLERNNIKQAANNSLLLHLLKSQTIPK-PMNGHSHSERGSIFEESSTPTTIDEYSDNNP 422 SL ++ + S + S ++P ++ HS + G + + EY+D P Sbjct: 2463 ESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRP 2522 Query: 423 SFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDI-K 481 + D + S + +PI+ S + E S+ + ++TW I Sbjct: 2523 AKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSL-------PRVSTWRRTGSSSSILS 2575 Query: 482 EDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIE 541 ++S+ +K + V + K + K T + N+ S N+ + +S Sbjct: 2576 ASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGAT 2635 Query: 542 SPSTNRTTPVSTPPLLTSSK------AGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTA 595 + + ++T P ++ ++ PIN + N+PP + S SEK Sbjct: 2636 NGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSV-SEKANPNI 2694 Query: 596 SNHSMDLTKSKDPPGEKPAQNEGAQN 621 + + K G P + G +N Sbjct: 2695 KDSKDNQAKQNVGNGSVPMRTVGLEN 2720 >gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] Length = 3062 Score = 38.9 bits (89), Expect = 0.029 Identities = 51/204 (25%), Positives = 79/204 (38%), Gaps = 27/204 (13%) Query: 419 DNNPSFTD-DSSGDESSYSNCVPIDLSCKHRTEKSES-------------DQPVSLDNFT 464 D + S TD D G + S++ + D S R K E D S +++ Sbjct: 2199 DESDSLTDYDIVGGKESFTASLKFDDSGSWRGRKEEYVTGQEFHSDTDHLDSMQSEESYG 2258 Query: 465 QSLLNTWDPKVPDVD--------IKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKN 516 + ++ D D D I+++ + + + L +L ++EN N Sbjct: 2259 DYIYDSNDQDDDDDDGIDEEGGGIRDENGKPRCQNVAEDMDIQLCASILNENSDENENIN 2318 Query: 517 TSP--QGVHNDVSKFNTQNYARTSVIESPSTNR-TTPVSTPPLLTSSKAG-SPINLSQHS 572 T +H+ S Q + SPS N T S P T+ AG S NL H Sbjct: 2319 TMILLDKMHS-CSSLEKQQRVNVVQLASPSENNLVTEKSNLPEYTTEIAGKSKENLLNHE 2377 Query: 573 LVIKWNSPPYVCSTQSEKLTNTAS 596 +V+K PP + T+SEK AS Sbjct: 2378 MVLKDVLPPIIKDTESEKTFGPAS 2401 >gi|56676335 RAP1 interacting factor 1 [Homo sapiens] Length = 2472 Score = 38.9 bits (89), Expect = 0.029 Identities = 77/327 (23%), Positives = 122/327 (37%), Gaps = 59/327 (18%) Query: 433 SSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKL 492 + YS P+++ R K +S ++ + D DI QD +++ + Sbjct: 1095 TQYSQEEPMEIPTLTRKPKEDSKMMITEEQM-------------DSDIVIPQDVTEDCGM 1141 Query: 493 NSHQKVTLLQLLLGHKNEENVEKNTSPQ--GVHNDVSKFNTQNYARTS-----------V 539 H + + L NE TSP+ +ND K + +TS V Sbjct: 1142 AEHLEKSSLS-----NNECGSLDKTSPEMSNSNNDERKKALISSRKTSTECASSTENSFV 1196 Query: 540 IESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHS 599 + S S + TT TPP TS + ++ N P + T T N+ Sbjct: 1197 VSSSSVSNTTVAGTPPYPTSRRQTF---ITLEKFDGSENRPFSPSPLNNISSTVTVKNNQ 1253 Query: 600 MDLTKSKDPPGEKPAQNEGAQNSA--------TFSASKLLQNLAQCGMQSSMSVEEQRPS 651 + K+ P K Q EG + + T +S+ Q G + S + P Sbjct: 1254 ETMIKTDFLP--KAKQREGTFSKSDSEKIVNGTKRSSRRAGKAEQTGNKRSKPLMRSEPE 1311 Query: 652 KQLLTGNTDKPIGMIDRL--NSPLLSNKTNAVEENKAFSSQPTGPEPG--LSGSEIEN-- 705 K NT++ + I L N P L N+T V +N+ S+ T L + +EN Sbjct: 1312 K-----NTEESVEGIVVLENNPPGLLNQTECVSDNQVHLSESTMEHDNTKLKAATVENAV 1366 Query: 706 LLERRTVLQLLLGNPNKGKSEKKEKTP 732 LLE TV + + + E KE TP Sbjct: 1367 LLETNTVEEKNV----EINLESKENTP 1389 >gi|34577118 dopey family member 1 [Homo sapiens] Length = 2465 Score = 38.9 bits (89), Expect = 0.029 Identities = 53/258 (20%), Positives = 94/258 (36%), Gaps = 17/258 (6%) Query: 394 NGHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSE 453 +G S S G P T++ D+ +SS D+ V DL CK + Sbjct: 1111 SGCSQSSAGDNLSYEVDPETVNAQEDSQ--MPKESSPDDDVQQ--VVFDLICKVVSGLEV 1166 Query: 454 SDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENV 513 V+ +Q + PK D+D E+ ++ + Q L NE + Sbjct: 1167 ESASVT----SQLEIEAMPPKCSDIDPDEETIKIEDDSIQQSQNALL-------SNESSQ 1215 Query: 514 EKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSL 573 + S +G H V+ ++N + + + T + V++ + ++ S I S Sbjct: 1216 FLSVSAEGGHECVANGISRNSSSPCISGTTHTLHDSSVASIETKSRQRSHSSIQFSFKEK 1275 Query: 574 VIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQN 633 + + S +S K + + L + KD +K + + Q S FS L+N Sbjct: 1276 LSEKVSEKETIVKESGK--QPGAKPKVKLARKKDDDKKKSSNEKLKQTSVFFSDGLDLEN 1333 Query: 634 LAQCGMQSSMSVEEQRPS 651 CG +E S Sbjct: 1334 WYSCGEGDISEIESDMGS 1351 >gi|112734859 zinc finger protein 654 [Homo sapiens] Length = 581 Score = 38.1 bits (87), Expect = 0.049 Identities = 47/198 (23%), Positives = 84/198 (42%), Gaps = 44/198 (22%) Query: 406 EESSTPTTI---DEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPV-SLD 461 E S+ P+ D +D+NP+ DSS +E + +P+ S K R E +E + S++ Sbjct: 328 ESSAQPSETILWDVQTDSNPNQEKDSSSNEKQTIS-LPVSTS-KSRKESTEPKTCIESME 385 Query: 462 NFTQSLLNTW--------------DPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGH 507 T SL+ D K+PD++ + + S + +N H ++ L+ Sbjct: 386 KKTDSLVQNGNERSDDTVSNISLIDQKMPDIEPNSENNCSSSDIVNGHSEIEQTPLV--- 442 Query: 508 KNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIES--PSTNRTTPVSTPPLLTSSKAGSP 565 +S + D ++ T+N S++ S P + T PVS P SK Sbjct: 443 ---------SSDPALKIDTNRIRTEN---GSILPSVVPQEHNTLPVSQAP----SKPNLT 486 Query: 566 INLSQHSLVIKWNSPPYV 583 + + L++ + PYV Sbjct: 487 SEHTSYGLIL---TKPYV 501 >gi|154350236 hypothetical protein LOC56204 [Homo sapiens] Length = 1076 Score = 37.7 bits (86), Expect = 0.064 Identities = 48/243 (19%), Positives = 99/243 (40%), Gaps = 47/243 (19%) Query: 352 IIPSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTP 411 ++P+ + NS E+ ++K N + Q P + ++ E + ST Sbjct: 559 LVPNKCFTSFKNNSKEKCSLKHQTRN-------QCQNNPSEIIQSTYQETQNKSSSLSTS 611 Query: 412 TTIDEYSDNNPSFT------DDSSGDESSYSNCVPIDLS-CKHR---------------- 448 + + ++ +NN T + S+G + YSNC ID C ++ Sbjct: 612 SILSQHKENNLDLTSRFKEQEMSNGIDKQYSNCTTIDKQICTNKYKEKIINENYNPKFFG 671 Query: 449 ------TEKSESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQ 502 ++K++S V++ ++ LN ++ + D K + +N++LNS ++ Sbjct: 672 NLQSDDSKKNDSKIKVTVLEMSE-YLNKYESMSSNKDSKRPKTCEQNTQLNS------IE 724 Query: 503 LLLGHKNE----ENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLT 558 L NE + ++ + Q D + +QNY++ I+ + P +T L T Sbjct: 725 NYLNKDNEGFKCKKSDQLKNEQDKQEDPTNEKSQNYSQRRSIKDCLSTCEQPKNTEVLRT 784 Query: 559 SSK 561 + K Sbjct: 785 TLK 787 >gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] Length = 2432 Score = 37.4 bits (85), Expect = 0.083 Identities = 163/819 (19%), Positives = 283/819 (34%), Gaps = 150/819 (18%) Query: 319 KGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSP----KNAGYKNSLERNNIKQA 374 K S G A ++S + + SAT +G IP S ++AG K+S++ + Sbjct: 1123 KKQSGSAAGLAMITASGVTVTSRSAT-----LGKIPKSSALVSRSAGRKSSMDGAQNQDD 1177 Query: 375 ANNSLLLHL-LKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNP----------- 422 +L L+ +++P+P +S + G+ SS + I S P Sbjct: 1178 GYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKSAGLPVPKLREPSKTA 1237 Query: 423 ---------SFTDDSSG---DESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLNT 470 + TD G D S ++C + ++ + QPVS T Sbjct: 1238 LGSSLPGLVNQTDKEKGISSDNESVASCNSVKVN--------PAAQPVSSPAQTSLQPGA 1289 Query: 471 WDPKVPDVDIKE-------------DQDTSKNSKLNSHQKVTLLQ------------LLL 505 P V ++ + KNS + S+ T+ Q L Sbjct: 1290 KYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQGNLDSPSGSGVLSS 1349 Query: 506 GHKN---EENVEKN-----TSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLL 557 G + +NV+ N +SP H+ S N+ + + S + + L Sbjct: 1350 GSSSPLYSKNVDLNQSPLASSPSSAHSAPS--NSLTWGTNASSSSAVSKDGLGFQSVSSL 1407 Query: 558 TSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNE 617 +S I+LS + +S + S++ + LT +S+ T S+ P A Sbjct: 1408 HTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAA--- 1464 Query: 618 GAQNSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTDKPIGMIDRLNSPLLSNK 677 S F S L + S ++ K+ L + + L S+ Sbjct: 1465 ----SPKFCRSTLPRK-----QDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHS 1515 Query: 678 TNAVEE---NKAFSSQPTGPEPGLSGSEIENLLERRTVLQLLLGNPNKGKSEKKEKTPLR 734 +++ N FSS + P + L TV Q+ L NP T LR Sbjct: 1516 AGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNP----------TMLR 1565 Query: 735 DESTQEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAK----SAPFLGMAPAVQR 790 S + +P D + N+++ L ++ S F V Sbjct: 1566 THSLSNADGQY------------DPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEVHG 1613 Query: 791 SAPALPVSEDFKSEPVSPQDFSFSKNGLLSRLLRQNQDSYLADDSDRSHRNNEMALLESK 850 S+ +L S S +P++ S+ L R L +Q+ A + + + +A E Sbjct: 1614 SSLSLVSSTS--SVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQS 1671 Query: 851 --NLCMVPKKRKLYTEPLENPFKKMKNNIVDAANNHSAPEVLYGSLLNQEELKFSRNDLE 908 N+ + + + E ++ +++ I ++A + ++N EL Sbjct: 1672 LGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCK----- 1726 Query: 909 FKYPAGHGSASESEHRSWARESKSFNVLKQLLLSENCVRDLSPHRSNSVADSKKKGHKNN 968 G+G+A ++ R + S + S N S SN +DSKKK KN Sbjct: 1727 -----GNGTAQSADLRIRRQHSSDS------VSSINSATSHSSVGSNIESDSKKKKRKNW 1775 Query: 969 VTNSKPEFSISSLNGLMYSSTQPSSCMDNRTFSYPGVVKTPVSPTFPEHLGCAGSRP--- 1025 V + F + S S ++ T S P SP P H G GS P Sbjct: 1776 VNELRSSFKQAFGKKKSPKSASSHSDIEEMTDS-----SLPSSPKLP-HNGSTGSTPLLR 1829 Query: 1026 ---ESGLLNGCSMPSEKGPIKWVITDAEKNEYEKDSPRL 1061 + L++ C M SE + + + E + RL Sbjct: 1830 NSHSNSLISEC-MDSEAETVMQLRNELRDKEMKLTDIRL 1867 >gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2 isoform 5 [Homo sapiens] Length = 729 Score = 37.4 bits (85), Expect = 0.083 Identities = 73/395 (18%), Positives = 140/395 (35%), Gaps = 32/395 (8%) Query: 352 IIPSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTP 411 ++P P N Y ++ + K A N+ H + I ++ ++GS S Sbjct: 313 VVPFLPVNPEYSSTRNQGRQKLARFNA---HEFATLVIDI-LSDAKRRQQGSSLSGSKDN 368 Query: 412 TTIDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDN-------FT 464 + + NN + D+ Y + V D T S++++ SLD+ Sbjct: 369 VELILKTINNQHSVESQDNDQPDYDS-VASDEDTDLETTASKTNRQKSLDSDLSDGPVTV 427 Query: 465 QSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHN 524 Q + + V + K Q N+ L+ ++ +L N+ K + Sbjct: 428 QEFMEVKNALVAS-EAKIQQLMKVNNNLSDELRIMQKKLQTLQSENSNLRKQATTNVYQV 486 Query: 525 DVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGSPINLSQHSLVIKWNSPPYVC 584 T +S+ PS + P+S + K P+ + + P+ Sbjct: 487 QTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPEESRMRLQPFPA 546 Query: 585 STQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMS 644 + N+ D T + P + +G Q S + L+ + A+ + S + Sbjct: 547 HASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPT 606 Query: 645 VEEQRPSKQLLTGNTDKPIGMIDRLNSPLLSNKTNAVEENKAFSSQPTGPEPGLSGSEIE 704 + PS + + T++ I L A +ENK S P ++ +E+ Sbjct: 607 L----PSTEDVIRKTEQITKNIQEL--------LRAAQENKHDSYIPCSERIHVAVTEMA 654 Query: 705 NLLER-------RTVLQLLLGNPNKGKSEKKEKTP 732 L + RT L+LL + + +SE K+ P Sbjct: 655 ALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLP 689 >gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical region 1 [Homo sapiens] Length = 1400 Score = 37.0 bits (84), Expect = 0.11 Identities = 122/659 (18%), Positives = 226/659 (34%), Gaps = 121/659 (18%) Query: 220 HHVGQSGTKVMS----EPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLSSEAH 275 H+ G S TK S E ++ A++ + + + + +VA +L L + + Sbjct: 273 HNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKL--LTKTTKN 330 Query: 276 LQQYSREHALKTQNANQAASERLAAMARLQENGQKDVGSYQLPKGMSSHLNGQARTSSSK 335 +Q+ +A+E ++A E+G + P N + RT++ Sbjct: 331 IQE------------TISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRE-RTANEN 377 Query: 336 LMASKSSATVFQNPMGIIPSSPKNAGYKNSLERNNIKQAANNSLLL----------HLLK 385 S + T + ++P AG N + AN + L Sbjct: 378 TTLSPAEPTENRERTANENTAPFPAG-----PTENREMTANENTTLFPAEPTEHGERTAN 432 Query: 386 SQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNPSFTD---DSSGDESSYSNCVPI- 441 T P P H ER + + +P E+ + P D SS + + + P+ Sbjct: 433 ENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLA 492 Query: 442 -DLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTL 500 + + E +E+ + + +N T S P P ++N + +++K TL Sbjct: 493 NENTTPSPAEPTENRERTANENTTPS------PAGP----------TENRETTANEKTTL 536 Query: 501 LQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSS 560 + E + T+P T+N RT P N T+S Sbjct: 537 SPVEPTENRETTANEKTTPSPAE------PTENGQRT-----PFANEK---------TTS 576 Query: 561 KAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQ 620 + P + + + N+ P + +E N + T S P E + A Sbjct: 577 SSAEPTEHGERTPLANENTTP----SPAEPTENRERTANEKTTPSPAEPTENGDRTPLAN 632 Query: 621 NSATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTDK-PIGMIDRLNSPLLSNKTN 679 T S ++ +N G ++ + E+ S T + ++ P+ + SP + Sbjct: 633 EKTTPSLAEPTEN----GQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENR 688 Query: 680 AVEENKAFSSQPTGPEPG--LSGSEIENLL-------ERRTVLQLLLGNPNKGKSEKKEK 730 N+ + P GP ++ +E L RT + +P + +E ++ Sbjct: 689 ERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAE-PTENGQR 747 Query: 731 TPLRDEST-------QEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAKSAPFLG 783 TP +E T EH ER + P P N + + K+ PF Sbjct: 748 TPFANEKTTSSSAEPTEHGERT---PLANENTTLSPAG----PTENRERTANEKTTPF-- 798 Query: 784 MAPAVQRSAPALPVS--EDFKSEPVSPQDFSFSKNGLLSRLLRQNQDSYLADDSDRSHR 840 PA P E +E +P ++NG + L + LA+ ++ R Sbjct: 799 ---------PAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKR 848 >gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens] Length = 2073 Score = 37.0 bits (84), Expect = 0.11 Identities = 57/262 (21%), Positives = 104/262 (39%), Gaps = 25/262 (9%) Query: 423 SFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQ----PVSLDNFTQSLLNTWDPKV--- 475 S T +SS + ++ +C +C+ + +DQ +LD+ QS ++ V Sbjct: 1547 SLTQESSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSH 1606 Query: 476 PDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQ--- 532 P ++ S + NS+ +++ Q + + +N+E TSP VS + Q Sbjct: 1607 PGQSVRSVNSPSVPALENSYAQISPDQSAISVPSLQNME--TSPMMDVPSVSDHSQQVVD 1664 Query: 533 -NYARTSVIESPSTNRTTPVSTPPLLTSSKA--GSPINLSQHSLVIKWNSPPYVCSTQSE 589 ++ IES + N P S + S GS N +S + + C+ + Sbjct: 1665 SGFSDLGSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNLTSSSLTQSSCAVTQQ 1724 Query: 590 KLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQR 649 + S + T PP +G S+S Q LAQC M ++ + Sbjct: 1725 MSNISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSS---QQLAQCSMAANFT----- 1776 Query: 650 PSKQL--LTGNTDKPIGMIDRL 669 P QL + ++ IG+ +R+ Sbjct: 1777 PPMQLAEIPETSNANIGLYERM 1798 >gi|149944526 additional sex combs like 3 [Homo sapiens] Length = 2248 Score = 37.0 bits (84), Expect = 0.11 Identities = 139/705 (19%), Positives = 259/705 (36%), Gaps = 84/705 (11%) Query: 157 LKEQGYALSHDSLKVEKDLRCYGVASSHLKTLLKKSKVKDQKPDTNLPDVTKNLIRD--- 213 L+++ Y S D + R ++ L+ S + PD +N RD Sbjct: 902 LQDKQYISSVDKAPFSEGSRNKTHKQGSTQSRLETSHTSKSSEPSKSPDGIRNESRDSEI 961 Query: 214 --RFAESPHHVGQSGTKVMSEPLSCAARLQAVASMVEKRASPATSPKPSVACSQLALLLS 271 R H G K + R + +S EK P P+ QL+ + Sbjct: 962 SKRKTAEQHSFGICKEKRARIEDDQSTRNISSSSPPEKEQPPREEPRVPPLKIQLSKI-- 1019 Query: 272 SEAHLQQYSREHALKTQNANQAASERLAAMARLQENGQKDVGSYQLPKGMSSHLNGQART 331 +K+Q ++ S A +G ++ G+ L + +A+ Sbjct: 1020 --------GPPFIIKSQPVSKPESR---ASTSTSVSGGRNTGARTLADIKARAQQARAQR 1068 Query: 332 SSSKLMASKSSATVFQNPMGIIPSSPKNAGYKNSLERNNIKQAANNSLLLHLL---KSQT 388 ++ A ++A++ MG K + E+ K A + HL K Sbjct: 1069 EAAAAAAVAAAASIVSGAMGSPGEGGKTRTLAHIKEQTKAKLFAKHQARAHLFQTSKETR 1128 Query: 389 IPKPMNGHSHSERGSIFEESSTPTTIDEYSDN----NPSFTDDSSGDESSYSNCVPIDLS 444 +P P+ S E E SSTP T E S NP+ S+ + S Sbjct: 1129 LPPPL---SSKEGPPNLEVSSTPETKMEGSTGVIIVNPNCRSPSNKSAHLRETTTVLQQS 1185 Query: 445 C------KHRTEKS--ESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQ 496 + T+ S SD+ + + + ++ ++++ + V + +KNS S Sbjct: 1186 LNPSKLPETATDLSVHSSDENIPVSHLSEKIVSSTSSENSSVPML----FNKNSVPVSVC 1241 Query: 497 KVTLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPV----- 551 + + H +V+K++ V + + + N + I+ T + Sbjct: 1242 STAISGAIKEHPFVSSVDKSSVLMSVDSANTTISACNISMLKTIQGTDTPCIAIIPKCIE 1301 Query: 552 STPPLLTSSKAGSPINLSQHSLVIKWNSPPYVCSTQSEKL-TNTASNHSMDLTKSK---D 607 STP T+ + ++ L+I +S + STQ + T + N+ +L+ S Sbjct: 1302 STPISATTEGSSISSSMDDKQLLISSSSASNLVSTQYTSVPTPSIGNNLPNLSTSSVLIP 1361 Query: 608 P-------PGEKPAQNEGAQNSATFSASKLLQNLAQCGMQSSMSVEEQ---RPSKQLLTG 657 P P EK A G++ AT S ++ C S++V + P+ + TG Sbjct: 1362 PMGINNRFPSEKIA-IPGSEEQATVSMGTTVRAALSC--SDSVAVTDSLVAHPTVAMFTG 1418 Query: 658 NTDKPIGMIDRLNSPLLSNKT---NAVEENKAFSS-QPTGPEPGLSGSEIENLLERRTV- 712 N I D + P LS ++ N+ N+A +S +P P G + + I + + + Sbjct: 1419 NM-LTINSYD--SPPKLSAESLDKNSGPRNRADNSGKPQQPPGGFAPAAINRSIPCKVIV 1475 Query: 713 ---------LQLLLGNPNKGKSEKKEKTPLRDESTQEHSERALSEQILMVKIKSEPCDDL 763 L L + + S + P+R E+ S + ++ + V + EP + Sbjct: 1476 DHSTTLTSSLSLTVSVESSEASLDLQGRPVRTEA----SVQPVACPQVSVISRPEPVANE 1531 Query: 764 QIPNTNVHLSHDAKSAPFLGMAPAVQRSAPALPVSEDFKSEPVSP 808 I +++ ++ A + PA S LP+ D +EP +P Sbjct: 1532 GIDHSSTFIAASAAKQDSKTL-PATCTSLRELPLVPDKLNEPTAP 1575 >gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo sapiens] Length = 1393 Score = 36.6 bits (83), Expect = 0.14 Identities = 91/477 (19%), Positives = 166/477 (34%), Gaps = 87/477 (18%) Query: 388 TIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNPSFTD---DSSGDESSYSNCVPI--D 442 T P P H ER + + +P E+ + P D SS + + + P+ + Sbjct: 373 TTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANE 432 Query: 443 LSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQ 502 + E +E+ + + +N T S P P ++N + +++K TL Sbjct: 433 NTTPSPAEPTENRERTANENTTPS------PAGP----------TENRETTANEKTTLSP 476 Query: 503 LLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKA 562 + E + T+P T+N RT P N T+S + Sbjct: 477 VEPTENRETTANEKTTPSPAE------PTENGQRT-----PFANEK---------TTSSS 516 Query: 563 GSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNS 622 P + + + N+ P + +E N + T S P E + A Sbjct: 517 AEPTEHGERTPLANENTTP----SPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEK 572 Query: 623 ATFSASKLLQNLAQCGMQSSMSVEEQRPSKQLLTGNTDK-PIGMIDRLNSPLLSNKTNAV 681 T S ++ +N G ++ + E+ S T + ++ P+ + SP + Sbjct: 573 TTPSLAEPTEN----GQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRER 628 Query: 682 EENKAFSSQPTGPEPG--LSGSEIENLL-------ERRTVLQLLLGNPNKGKSEKKEKTP 732 N+ + P GP ++ +E L RT + +P + +E ++TP Sbjct: 629 TANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAE-PTENGQRTP 687 Query: 733 LRDEST-------QEHSERALSEQILMVKIKSEPCDDLQIPNTNVHLSHDAKSAPFLGMA 785 +E T EH ER + P + P N + + K+ PF Sbjct: 688 FANEKTTSSSAEPTEHGERT---PLANENTTLSPAE----PTENRERTANEKTTPF---- 736 Query: 786 PAVQRSAPALPVS--EDFKSEPVSPQDFSFSKNGLLSRLLRQNQDSYLADDSDRSHR 840 PA P E +E +P ++NG + L + LA+ ++ R Sbjct: 737 -------PAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKR 786 >gi|196114970 protein tyrosine phosphatase, non-receptor type 12 isoform 3 [Homo sapiens] Length = 650 Score = 36.6 bits (83), Expect = 0.14 Identities = 74/357 (20%), Positives = 135/357 (37%), Gaps = 58/357 (16%) Query: 363 KNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERG-SIFEESSTPTTIDEYSDNN 421 ++++E+ + K N S + + Q PK +G++ RG +I +S++P D+ S Sbjct: 290 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 349 Query: 422 PSFTDDSSGDESSYSNCVPIDLSCKHRT------EKSESDQPVSLDNFTQSLLN--TW-- 471 +D + GD +S ++CV ++ ++ E SD P D TW Sbjct: 350 ELSSDLNVGD-TSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSF 408 Query: 472 ---DPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSP--------- 519 + +P D+ E + N + +T + NTSP Sbjct: 409 HGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFT 468 Query: 520 QGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGS-----PINLSQHSLV 574 +H+D S + +N + TN +T +T TS+++ S P+++++H++ Sbjct: 469 NPLHSDDSDSDERN--SDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIA 526 Query: 575 IKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNL 634 T S D+ S+D P P E S ++ Sbjct: 527 -----------------GTTHSGAEKDVDVSEDSP---PPLPERTPESFVLASEHNTPVR 566 Query: 635 AQCGMQSSMSVEEQRPSKQLLTGNTDK---PIGMIDRLN----SPLLSNKTNAVEEN 684 ++ S EQ+ S+ L+T +K P G I P S+K + EN Sbjct: 567 SEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISEN 623 >gi|196114967 protein tyrosine phosphatase, non-receptor type 12 isoform 2 [Homo sapiens] Length = 661 Score = 36.6 bits (83), Expect = 0.14 Identities = 74/357 (20%), Positives = 135/357 (37%), Gaps = 58/357 (16%) Query: 363 KNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERG-SIFEESSTPTTIDEYSDNN 421 ++++E+ + K N S + + Q PK +G++ RG +I +S++P D+ S Sbjct: 301 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 360 Query: 422 PSFTDDSSGDESSYSNCVPIDLSCKHRT------EKSESDQPVSLDNFTQSLLN--TW-- 471 +D + GD +S ++CV ++ ++ E SD P D TW Sbjct: 361 ELSSDLNVGD-TSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSF 419 Query: 472 ---DPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSP--------- 519 + +P D+ E + N + +T + NTSP Sbjct: 420 HGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFT 479 Query: 520 QGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGS-----PINLSQHSLV 574 +H+D S + +N + TN +T +T TS+++ S P+++++H++ Sbjct: 480 NPLHSDDSDSDERN--SDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIA 537 Query: 575 IKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNL 634 T S D+ S+D P P E S ++ Sbjct: 538 -----------------GTTHSGAEKDVDVSEDSP---PPLPERTPESFVLASEHNTPVR 577 Query: 635 AQCGMQSSMSVEEQRPSKQLLTGNTDK---PIGMIDRLN----SPLLSNKTNAVEEN 684 ++ S EQ+ S+ L+T +K P G I P S+K + EN Sbjct: 578 SEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISEN 634 >gi|196114951 protein tyrosine phosphatase, non-receptor type 12 isoform 1 [Homo sapiens] Length = 780 Score = 36.6 bits (83), Expect = 0.14 Identities = 74/357 (20%), Positives = 135/357 (37%), Gaps = 58/357 (16%) Query: 363 KNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERG-SIFEESSTPTTIDEYSDNN 421 ++++E+ + K N S + + Q PK +G++ RG +I +S++P D+ S Sbjct: 420 ESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQ 479 Query: 422 PSFTDDSSGDESSYSNCVPIDLSCKHRT------EKSESDQPVSLDNFTQSLLN--TW-- 471 +D + GD +S ++CV ++ ++ E SD P D TW Sbjct: 480 ELSSDLNVGD-TSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSF 538 Query: 472 ---DPKVPDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHKNEENVEKNTSP--------- 519 + +P D+ E + N + +T + NTSP Sbjct: 539 HGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFT 598 Query: 520 QGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLTSSKAGS-----PINLSQHSLV 574 +H+D S + +N + TN +T +T TS+++ S P+++++H++ Sbjct: 599 NPLHSDDSDSDERN--SDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIA 656 Query: 575 IKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPAQNEGAQNSATFSASKLLQNL 634 T S D+ S+D P P E S ++ Sbjct: 657 -----------------GTTHSGAEKDVDVSEDSP---PPLPERTPESFVLASEHNTPVR 696 Query: 635 AQCGMQSSMSVEEQRPSKQLLTGNTDK---PIGMIDRLN----SPLLSNKTNAVEEN 684 ++ S EQ+ S+ L+T +K P G I P S+K + EN Sbjct: 697 SEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISEN 753 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 36.2 bits (82), Expect = 0.19 Identities = 57/294 (19%), Positives = 106/294 (36%), Gaps = 50/294 (17%) Query: 354 PSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTT 413 P S + K++ +R+ + N +++S+ I + + + E S SS+ +T Sbjct: 80 PPSGASQTIKSTTKRS--PKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSST 137 Query: 414 IDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLN---- 469 I + + +S + + + K+RT+K + +P +D L N Sbjct: 138 IRKIKSSK------NSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 191 Query: 470 --------------TWDPKV-------PDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHK 508 + PK+ P + + DTSK + L +++ T+ K Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET-----K 246 Query: 509 NEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTP--------PLLTSS 560 K TS G S TQ+ +TS + T++ TP P LT+ Sbjct: 247 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 306 Query: 561 KAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPA 614 K +P + + +P T + T + TKS ++PA Sbjct: 307 KEPTPTTPKEPAS----TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 356 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 36.2 bits (82), Expect = 0.19 Identities = 57/294 (19%), Positives = 106/294 (36%), Gaps = 50/294 (17%) Query: 354 PSSPKNAGYKNSLERNNIKQAANNSLLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTT 413 P S + K++ +R+ + N +++S+ I + + + E S SS+ +T Sbjct: 121 PPSGASQTIKSTTKRS--PKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSST 178 Query: 414 IDEYSDNNPSFTDDSSGDESSYSNCVPIDLSCKHRTEKSESDQPVSLDNFTQSLLN---- 469 I + + +S + + + K+RT+K + +P +D L N Sbjct: 179 IRKIKSSK------NSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK 232 Query: 470 --------------TWDPKV-------PDVDIKEDQDTSKNSKLNSHQKVTLLQLLLGHK 508 + PK+ P + + DTSK + L +++ T+ K Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET-----K 287 Query: 509 NEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTP--------PLLTSS 560 K TS G S TQ+ +TS + T++ TP P LT+ Sbjct: 288 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 347 Query: 561 KAGSPINLSQHSLVIKWNSPPYVCSTQSEKLTNTASNHSMDLTKSKDPPGEKPA 614 K +P + + +P T + T + TKS ++PA Sbjct: 348 KEPTPTTPKEPAS----TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA 397 >gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens] Length = 967 Score = 36.2 bits (82), Expect = 0.19 Identities = 69/291 (23%), Positives = 116/291 (39%), Gaps = 52/291 (17%) Query: 319 KGMSSHLNGQARTSSSKLMASKSSATVFQNPMGIIPSSPKNAGYKNSLERNNIKQAANNS 378 + ++S + RTS S L + S AT + P +PS + + + +N S Sbjct: 155 RSITSSITTTKRTSHSSLSYTSSIATS-ETPSHTVPS------FTSLITTTESTSHSNPS 207 Query: 379 LLLHLLKSQTIPKPMNGHSHSERGSIFEESSTPTTIDEYSDNNPSFTDDSSGDESSYSNC 438 L + ++T SHS IF +S+ TTI+ S + PSFT + E++ + Sbjct: 208 LTSAITTTET-------RSHSP--PIF--TSSITTIETTSHSTPSFTSLMTTTETT--SL 254 Query: 439 VPIDLSCKHRTEKSESDQPVSLDNFTQSLLNTWDPKVPDVDIKEDQDTSKNSKLNSHQKV 498 P + T ++ S P S FT S+ T P T++++ SH + Sbjct: 255 SPPAFTFSISTTETNSHSPPS---FTSSIATTETPSHSPPSFTSLITTTEST---SHSPL 308 Query: 499 TLLQLLLGHKNEENVEKNTSPQGVHNDVSKFNTQNYARTSVIESPSTNRTTPVSTPPLLT 558 + ++ T+ + + F TS I + T TP S L+T Sbjct: 309 SFTSVI------------TTTESTSHSTPSF-------TSSIATTETTSHTPPSFTSLIT 349 Query: 559 SSKAGSPINLSQHSLVIKW----NSPPYVCSTQSEKLTNTASNHSMDLTKS 605 +++ S N S SL+ +SPP S S T ++HS + S Sbjct: 350 TTETPSHSNPSFTSLITATESTSHSPP---SFTSAIATTGITSHSTPIFTS 397 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.123 0.342 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,135,259 Number of Sequences: 37866 Number of extensions: 2134503 Number of successful extensions: 6423 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 6 Number of HSP's successfully gapped in prelim test: 128 Number of HSP's that attempted gapping in prelim test: 6237 Number of HSP's gapped (non-prelim): 332 length of query: 1158 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1045 effective length of database: 13,968,660 effective search space: 14597249700 effective search space used: 14597249700 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.