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Search of human proteins with 57222568
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57222568 myeloid/lymphoid or mixed-lineage leukemia
(trithorax homolog, Drosophila); translocated to, 6 [Homo sapiens]
(1093 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora... 2191 0.0
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca... 670 0.0
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat... 664 0.0
gi|51173722 bromodomain and PHD finger-containing protein 1 isof... 172 2e-42
gi|51173720 bromodomain and PHD finger-containing protein 1 isof... 172 2e-42
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 165 2e-40
gi|11321642 bromodomain containing protein 1 [Homo sapiens] 160 8e-39
gi|19923609 PHD finger protein 17 short isoform [Homo sapiens] 142 2e-33
gi|40556393 PHD finger protein 17 long isoform [Homo sapiens] 142 2e-33
gi|40556370 PHD finger protein 15 [Homo sapiens] 138 3e-32
gi|117190334 PHD finger protein 16 [Homo sapiens] 137 7e-32
gi|7662006 PHD finger protein 16 [Homo sapiens] 137 7e-32
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens] 134 5e-31
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens] 134 5e-31
gi|45504380 jumonji domain containing 2B [Homo sapiens] 107 5e-23
gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens] 104 4e-22
gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens] 104 4e-22
gi|98986459 jumonji domain containing 2A [Homo sapiens] 101 4e-21
gi|28559039 mediator complex subunit 1 [Homo sapiens] 76 2e-13
gi|55750053 atrophin-1 [Homo sapiens] 74 6e-13
gi|55750041 atrophin-1 [Homo sapiens] 74 6e-13
gi|151301154 mucin 6, gastric [Homo sapiens] 73 2e-12
gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens] 69 2e-11
gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens] 69 2e-11
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 66 2e-10
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 65 3e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 64 6e-10
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 64 1e-09
gi|57864582 hornerin [Homo sapiens] 62 2e-09
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 62 3e-09
>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 6 [Homo sapiens]
Length = 1093
Score = 2191 bits (5677), Expect = 0.0
Identities = 1093/1093 (100%), Positives = 1093/1093 (100%)
Query: 1 MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERA 60
MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERA
Sbjct: 1 MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERA 60
Query: 61 ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTC 120
ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTC
Sbjct: 61 ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTC 120
Query: 121 YICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180
YICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH
Sbjct: 121 YICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180
Query: 181 FSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKK 240
FSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKK
Sbjct: 181 FSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKK 240
Query: 241 SRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKG 300
SRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKG
Sbjct: 241 SRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKG 300
Query: 301 KKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPK 360
KKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPK
Sbjct: 301 KKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPK 360
Query: 361 LEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRAR 420
LEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRAR
Sbjct: 361 LEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRAR 420
Query: 421 APSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGR 480
APSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGR
Sbjct: 421 APSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGR 480
Query: 481 PKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPS 540
PKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPS
Sbjct: 481 PKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPS 540
Query: 541 LSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTL 600
LSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTL
Sbjct: 541 LSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTL 600
Query: 601 PSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRG 660
PSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRG
Sbjct: 601 PSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRG 660
Query: 661 TSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIV 720
TSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIV
Sbjct: 661 TSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIV 720
Query: 721 EMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYG 780
EMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYG
Sbjct: 721 EMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYG 780
Query: 781 LPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLL 840
LPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLL
Sbjct: 781 LPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLL 840
Query: 841 QQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLL 900
QQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLL
Sbjct: 841 QQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLL 900
Query: 901 GGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLT 960
GGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLT
Sbjct: 901 GGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLT 960
Query: 961 PEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPP 1020
PEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPP
Sbjct: 961 PEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPP 1020
Query: 1021 LLPAGALVAPSLGNNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLSGAEGSGGGPKGG 1080
LLPAGALVAPSLGNNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLSGAEGSGGGPKGG
Sbjct: 1021 LLPAGALVAPSLGNNTSLMAAAAAAAAVAAAGGPPVLTAQTNPFLSLSGAEGSGGGPKGG 1080
Query: 1081 TADKGASANQEKG 1093
TADKGASANQEKG
Sbjct: 1081 TADKGASANQEKG 1093
>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform b [Homo sapiens]
Length = 1011
Score = 670 bits (1729), Expect = 0.0
Identities = 453/1045 (43%), Positives = 605/1045 (57%), Gaps = 155/1045 (14%)
Query: 1 MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERA 60
MKEM+GGCCVCSDERGWAENPLVYCDGH CSVAVHQACYGIVQVPTGPWFCRKCESQERA
Sbjct: 18 MKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERA 77
Query: 61 ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTC 120
ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANV TMEPIVLQ VPHDR+NKTC
Sbjct: 78 ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTC 137
Query: 121 YICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180
YIC+EQGRESKAA+GACMTCN+HGCRQAFHVTCAQ AGLLCEEE DNV+YCGYCKYH
Sbjct: 138 YICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYH 197
Query: 181 FSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKK 240
FSK+K S+ S S +S S S S Q+K HHE+ +KK
Sbjct: 198 FSKLKKSKRGSNR--------------------SYDQSLSDSSSHSQDK---HHEK-EKK 233
Query: 241 SRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSS------------------- 281
K+K++ KQKHKK+PE P+ L P + T +K +S S++
Sbjct: 234 KYKEKDKHKQKHKKQPEPSPA-LVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNA 292
Query: 282 -----SHHEASTQETSES-SRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASS--SSSS 333
S H +S ++ SE+ E KGKKSS+HS +G+K G+ + SA+S S
Sbjct: 293 NFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGS 352
Query: 334 SSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADL 393
S + G + SS+QS DF +F + D YS + S + + K +
Sbjct: 353 FSGTPGSVKSSSGSSVQSPQDFLSFTDSDL-RNDSYS-------HSQQSSATKDVHKGES 404
Query: 394 FEQKVVFSGFGPIMRFSTTTSSSGRARA--PSPGDYKSPHVTGSGASAGTHKRMPALSAT 451
Q+ + F ++ +T++ + + ++ SPGD + + +G +KR + T
Sbjct: 405 GSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAG-----YKR----AQT 455
Query: 452 PVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTG----GPAAPSLPSAQLAGFT 507
+ET +KEKK K +K+S+HGPGRPKG++N+E A+P+ A AG
Sbjct: 456 SGIEEET----VKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSI 511
Query: 508 ATAA---SP--FSGGSLV-----SSGLGGLSSRTFGPSGSLPSLSLESPLLGA---GIYT 554
+++ SP GSL SS +G S + G+ P+ + S LL A GIY
Sbjct: 512 TSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTF-SELLNAIHNGIYN 570
Query: 555 SNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRL-SRSPFTSTLPSSSASISTTQVF 613
SN +S + + STP+SSS L + L ++ + SP S + S++ +++TTQ
Sbjct: 571 SNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSP--SAVSSAAPAVATTQAN 628
Query: 614 SLAGSTFSLPSTHIFGT-PMGAVNPLLSQAESSHTEPDLEDCSFRC--RGTSPQESLSSM 670
+L+GS+ S +H++G ++ L++Q+E++ T+ DL D S RG+SP+ SLS
Sbjct: 629 TLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSRNLVGRGSSPRGSLSPR 688
Query: 671 SPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQ-GDGEAGV-------NIVEM 722
SP+SSL +DQ G L+ P ++EQLLE+Q +G+ + +I+ M
Sbjct: 689 SPVSSLQIRYDQP-----GNSSLENLPPVAASIEQLLERQWSEGQQFLLEQGTPSDILGM 743
Query: 723 LKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLP 782
LK+LH LQ EN+RL+EQI +LTAKKERLQ+LN QLSVPFP + A P+ + + +
Sbjct: 744 LKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTI-TANPSPSHQI---HTFS 799
Query: 783 PQ-AGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQ 841
Q A ++DSL++SKSP +S DNSL ++D S S SSSS STPPP
Sbjct: 800 AQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSSSSAL--STPPP---AG 854
Query: 842 QSPATLPLALPGAPAPLPPQPQNGL-------GRAPGAAGLGAMPMAEGLLGGLAGSGGL 894
QSPA + G Q NG+ G P + + A+ G++G L G+ L
Sbjct: 855 QSPAQQGSGVSGV------QQVNGVTVGALASGMQPVTSTIPAVSAVGGIIGALPGN-QL 907
Query: 895 PLNGLLGGLNG------AAAPNPASLSQAGGAP--TLQLPGCLNS-------LTEQQRHL 939
+NG++G LNG + NP L+ P T +P L + L++QQR +
Sbjct: 908 AINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLTNSASGLGLLSDQQRQI 967
Query: 940 LQQQEQQLQQLQQLLASPQLTPEHQ 964
L Q QQ QQLL S QLTP H+
Sbjct: 968 LIHQ----QQFQQLLNSQQLTPVHR 988
>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
to, 10 isoform a [Homo sapiens]
Length = 1027
Score = 664 bits (1713), Expect = 0.0
Identities = 453/1061 (42%), Positives = 604/1061 (56%), Gaps = 171/1061 (16%)
Query: 1 MKEMVGGCCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERA 60
MKEM+GGCCVCSDERGWAENPLVYCDGH CSVAVHQACYGIVQVPTGPWFCRKCESQERA
Sbjct: 18 MKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRKCESQERA 77
Query: 61 ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTC 120
ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANV TMEPIVLQ VPHDR+NKTC
Sbjct: 78 ARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTMEPIVLQSVPHDRYNKTC 137
Query: 121 YICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180
YIC+EQGRESKAA+GACMTCN+HGCRQAFHVTCAQ AGLLCEEE DNV+YCGYCKYH
Sbjct: 138 YICDEQGRESKAATGACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNGADNVQYCGYCKYH 197
Query: 181 FSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKK 240
FSK+K S+ S S +S S S S Q+KH HE+ +KK
Sbjct: 198 FSKLKKSKRGSNR--------------------SYDQSLSDSSSHSQDKH---HEK-EKK 233
Query: 241 SRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSS------------------ 282
K+K++ KQKHKK+PE P+ L P + T +K +S S++S
Sbjct: 234 KYKEKDKHKQKHKKQPEPSPA-LVPSLTVTTEKTYTSTSNNSISGSLKRLEDTTARFTNA 292
Query: 283 ------HHEASTQETSES-SRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSS--SSS 333
H +S ++ SE+ E KGKKSS+HS +G+K G+ + SA+S S
Sbjct: 293 NFQEVSAHTSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQGS 352
Query: 334 SSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADL 393
S + G + SS+QS DF +F + D YS + S + + K +
Sbjct: 353 FSGTPGSVKSSSGSSVQSPQDFLSFTDSDL-RNDSYSH-------SQQSSATKDVHKGES 404
Query: 394 FEQKVVFSGFGPIMRFSTTTSSSGRARA--PSPGDYKSPHVTGSGASAGTHKRMPALSAT 451
Q+ + F ++ +T++ + + ++ SPGD + + +G +KR + T
Sbjct: 405 GSQEGGVNSFSTLIGLPSTSAVTSQPKSFENSPGDLGNSSLPTAG-----YKR----AQT 455
Query: 452 PVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTG----GPAAPSLPSAQLAGFT 507
+ET +KEKK K +K+S+HGPGRPKG++N+E A+P+ A AG
Sbjct: 456 SGIEEET----VKEKKRKGNKQSKHGPGRPKGNKNQENVSHLSVSSASPTSSVASAAGSI 511
Query: 508 ATAA---SP--FSGGSLVS-----SGLGGLSSRTFGPSGSLPSLSLESPLLGA------- 550
+++ SP GSL S S +G S + G+ P+ + S LL A
Sbjct: 512 TSSSLQKSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGACPTTTF-SELLNAIHNDRGD 570
Query: 551 ------------GIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSR-SPFT 597
GIY SN +S + + STP+SSS L + L ++ SP
Sbjct: 571 SSTLTKQELKFIGIYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSSGHLQQVGALSP-- 628
Query: 598 STLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGA-VNPLLSQAESSHTEPDLEDCSF 656
S + S++ +++TTQ +L+GS+ S +H++G + + L++Q+E++ T+ DL D S
Sbjct: 629 SAVSSAAPAVATTQANTLSGSSLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDLGDNSR 688
Query: 657 RC--RGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQ-GDG 713
RG+SP+ SLS SP+SSL +DQ G L+ P ++EQLLE+Q +G
Sbjct: 689 NLVGRGSSPRGSLSPRSPVSSLQIRYDQP-----GNSSLENLPPVAASIEQLLERQWSEG 743
Query: 714 EAGV-------NIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPA 766
+ + +I+ MLK+LH LQ EN+RL+EQI +LTAKKERLQ+LN QLSVPFP +
Sbjct: 744 QQFLLEQGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAKKERLQLLNAQLSVPFPTI-T 802
Query: 767 ALPAANGPVPGPYGLPPQ-AGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSS 825
A P+ + + + Q A ++DSL++SKSP +S DNSL ++D S S SS
Sbjct: 803 ANPSPSHQI---HTFSAQTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLTSSGQSTSS 859
Query: 826 SSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGL-------GRAPGAAGLGAM 878
SS STPPP QSPA + G Q NG+ G P + + A+
Sbjct: 860 SSAL--STPPP---AGQSPAQQGSGVSGV------QQVNGVTVGALASGMQPVTSTIPAV 908
Query: 879 PMAEGLLGGLAGSGGLPLNGLLGGLNG------AAAPNPASLSQAGGAP--TLQLPGCLN 930
G++G L G+ L +NG++G LNG + NP L+ P T +P L
Sbjct: 909 SAVGGIIGALPGN-QLAINGIVGALNGVMQTPVTMSQNPTPLTHTTVPPNATHPMPATLT 967
Query: 931 S-------LTEQQRHLLQQQEQQLQQLQQLLASPQLTPEHQ 964
+ L++QQR +L Q QQ QQLL S QLTP H+
Sbjct: 968 NSASGLGLLSDQQRQILIHQ----QQFQQLLNSQQLTPVHR 1004
>gi|51173722 bromodomain and PHD finger-containing protein 1 isoform
2 [Homo sapiens]
Length = 1214
Score = 172 bits (435), Expect = 2e-42
Identities = 105/279 (37%), Positives = 151/279 (54%), Gaps = 54/279 (19%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 66
CC+C+D N +++CD C++AVHQ CYG+ +P G W CR+C +S RA V C
Sbjct: 276 CCICNDGECQNSNVILFCD--MCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331
Query: 67 LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPI-VLQYVPHDRFNKTCYICEE 125
LCP+K GA K+TD+G WAHVVCAL+IPEV FAN + +EPI ++++P R+ TCYIC++
Sbjct: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391
Query: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMK 185
+G SGAC+ C++ C AFHVTCAQ AGL ++++ V+ G FS K
Sbjct: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGL-----YMKMEPVRETGANGTSFSVRK 440
Query: 186 TSR---HSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG----- 237
T+ H+ G S RR + S S +E + G
Sbjct: 441 TAYCDIHTPPG--------------------SARRLPALSHSEGEEDEDEEEDEGKGWSS 480
Query: 238 -QKKSRKDKERLKQKH------KKRPESPPSILTPPVVP 269
+ K K K R+K K +KR +P +++ P +P
Sbjct: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAP--VVSVPCIP 517
Score = 32.0 bits (71), Expect = 3.3
Identities = 52/200 (26%), Positives = 70/200 (35%), Gaps = 30/200 (15%)
Query: 415 SSGRARAPSPGDYKSPHVTGSGASAGTHKRM-----PALSATPVPADETPETGLKEKKHK 469
SS + P P T S A + + P +S+TP + L KK+
Sbjct: 840 SSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNP 899
Query: 470 ASKRSRHGPGRPKGSRNKEGT----GGPAA-PSLPSAQLAGFTATAASPFSGGSLVSSGL 524
+ PGRP +R + T G P P LP S +
Sbjct: 900 KTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIM----------------SSLRQRK 943
Query: 525 GGLSSRTFGPSGSLPSLSLESPL--LGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGP 582
G S R S S S E P L A ++ P+ S + R CS P SSS
Sbjct: 944 RGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSS--DS 1001
Query: 583 PGTSALPRLSRSPFTSTLPS 602
+S+ + S TST PS
Sbjct: 1002 ESSSSSSSSAASDRTSTTPS 1021
>gi|51173720 bromodomain and PHD finger-containing protein 1 isoform
1 [Homo sapiens]
Length = 1220
Score = 172 bits (435), Expect = 2e-42
Identities = 105/279 (37%), Positives = 151/279 (54%), Gaps = 54/279 (19%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKC-ESQERAARVRCE 66
CC+C+D N +++CD C++AVHQ CYG+ +P G W CR+C +S RA V C
Sbjct: 276 CCICNDGECQNSNVILFCD--MCNLAVHQECYGVPYIPEGQWLCRRCLQSPSRA--VDCA 331
Query: 67 LCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPI-VLQYVPHDRFNKTCYICEE 125
LCP+K GA K+TD+G WAHVVCAL+IPEV FAN + +EPI ++++P R+ TCYIC++
Sbjct: 332 LCPNKGGAFKQTDDGRWAHVVCALWIPEVCFANTVFLEPIDSIEHIPPARWKLTCYICKQ 391
Query: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMK 185
+G SGAC+ C++ C AFHVTCAQ AGL ++++ V+ G FS K
Sbjct: 392 RG------SGACIQCHKANCYTAFHVTCAQQAGL-----YMKMEPVRETGANGTSFSVRK 440
Query: 186 TSR---HSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG----- 237
T+ H+ G S RR + S S +E + G
Sbjct: 441 TAYCDIHTPPG--------------------SARRLPALSHSEGEEDEDEEEDEGKGWSS 480
Query: 238 -QKKSRKDKERLKQKH------KKRPESPPSILTPPVVP 269
+ K K K R+K K +KR +P +++ P +P
Sbjct: 481 EKVKKAKAKSRIKMKKARKILAEKRAAAP--VVSVPCIP 517
Score = 32.0 bits (71), Expect = 3.3
Identities = 52/200 (26%), Positives = 70/200 (35%), Gaps = 30/200 (15%)
Query: 415 SSGRARAPSPGDYKSPHVTGSGASAGTHKRM-----PALSATPVPADETPETGLKEKKHK 469
SS + P P T S A + + P +S+TP + L KK+
Sbjct: 846 SSRGSLTPHPAACDKDGQTDSAAEESSSQETSKGLGPNMSSTPAHEVGRRTSVLFSKKNP 905
Query: 470 ASKRSRHGPGRPKGSRNKEGT----GGPAA-PSLPSAQLAGFTATAASPFSGGSLVSSGL 524
+ PGRP +R + T G P P LP S +
Sbjct: 906 KTAGPPKRPGRPPKNRESQMTPSHGGSPVGPPQLPIM----------------SSLRQRK 949
Query: 525 GGLSSRTFGPSGSLPSLSLESPL--LGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGP 582
G S R S S S E P L A ++ P+ S + R CS P SSS
Sbjct: 950 RGRSPRPSSSSDSDSDKSTEDPPMDLPANGFSGGNQPVKKSFLVYRNDCSLPRSSS--DS 1007
Query: 583 PGTSALPRLSRSPFTSTLPS 602
+S+ + S TST PS
Sbjct: 1008 ESSSSSSSSAASDRTSTTPS 1027
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
sapiens]
Length = 1205
Score = 165 bits (417), Expect = 2e-40
Identities = 103/281 (36%), Positives = 138/281 (49%), Gaps = 37/281 (13%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
CCVC D+ N +++CD C++AVHQ CYG+ +P G W CR C Q + V C L
Sbjct: 215 CCVCLDDECHNSNVILFCD--ICNLAVHQECYGVPYIPEGQWLCRCC-LQSPSRPVDCIL 271
Query: 68 CPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEEQ 126
CP+K GA K+T +G WAHVVCA++IPEV FAN + +EPI + +P R+ TCYIC+++
Sbjct: 272 CPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQK 331
Query: 127 GRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLE-------VDNVKYCGYCKY 179
G GA + C++ C AFHVTCAQ AGL + E + + V+ YC+
Sbjct: 332 G------LGAAIQCHKVNCYTAFHVTCAQRAGLFMKIEPMRETSLNGTIFTVRKTAYCE- 384
Query: 180 HFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHE---- 235
HS G G +G G + ++E E
Sbjct: 385 --------AHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGG 436
Query: 236 -RGQKKS--RKDKERLKQKHKKRPE----SPPSILTPPVVP 269
G K +K K LKQK KK PE PS L VP
Sbjct: 437 VSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPSTLPMLAVP 477
>gi|11321642 bromodomain containing protein 1 [Homo sapiens]
Length = 1058
Score = 160 bits (404), Expect = 8e-39
Identities = 79/181 (43%), Positives = 109/181 (60%), Gaps = 17/181 (9%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
CC+C D N +++CD C++AVHQ CYG+ +P G W CR C Q RA C L
Sbjct: 217 CCICMDGECQNSNVILFCD--MCNLAVHQECYGVPYIPEGQWLCRHC-LQSRARPADCVL 273
Query: 68 CPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPI-VLQYVPHDRFNKTCYICEEQ 126
CP+K GA K+TD+ W HVVCAL+IPEV FAN + +EPI ++ +P R+ TCY+C+++
Sbjct: 274 CPNKGGAFKKTDDDRWGHVVCALWIPEVGFANTVFIEPIDGVRNIPPARWKLTCYLCKQK 333
Query: 127 GRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLE-------VDNVKYCGYCKY 179
G GAC+ C++ C AFHVTCAQ AGL + E ++ +V+ YC
Sbjct: 334 G------VGACIQCHKANCYTAFHVTCAQKAGLYMKMEPVKELTGGGTTFSVRKTAYCDV 387
Query: 180 H 180
H
Sbjct: 388 H 388
>gi|19923609 PHD finger protein 17 short isoform [Homo sapiens]
Length = 509
Score = 142 bits (357), Expect = 2e-33
Identities = 86/241 (35%), Positives = 116/241 (48%), Gaps = 24/241 (9%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
C VC G N +V+CD C++ VHQACYGI++VP G W CR C + +C L
Sbjct: 206 CDVCQSPDGEDGNEMVFCD--KCNICVHQACYGILKVPEGSWLCRTC---ALGVQPKCLL 260
Query: 68 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEE 125
CP K GA+K T +G W HV CAL+IPEV + MEPI + ++P R+ C +C E
Sbjct: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE 320
Query: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMK 185
+ GA + C+ CR AFHVTCA GL + + E D VK+ YC H S K
Sbjct: 321 K-------FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRK 373
Query: 186 TSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKDK 245
G G+ G+ S R S +Q + H +K+ +
Sbjct: 374 PEESL----------GKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQL 423
Query: 246 E 246
E
Sbjct: 424 E 424
>gi|40556393 PHD finger protein 17 long isoform [Homo sapiens]
Length = 842
Score = 142 bits (357), Expect = 2e-33
Identities = 86/241 (35%), Positives = 116/241 (48%), Gaps = 24/241 (9%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
C VC G N +V+CD C++ VHQACYGI++VP G W CR C + +C L
Sbjct: 206 CDVCQSPDGEDGNEMVFCD--KCNICVHQACYGILKVPEGSWLCRTC---ALGVQPKCLL 260
Query: 68 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEE 125
CP K GA+K T +G W HV CAL+IPEV + MEPI + ++P R+ C +C E
Sbjct: 261 CPKKGGAMKPTRSGTKWVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNE 320
Query: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYHFSKMK 185
+ GA + C+ CR AFHVTCA GL + + E D VK+ YC H S K
Sbjct: 321 K-------FGASIQCSVKNCRTAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRK 373
Query: 186 TSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKDK 245
G G+ G+ S R S +Q + H +K+ +
Sbjct: 374 PEESL----------GKGAAQENGAPECSPRNPLEPFASLEQNREEAHRVSVRKQKLQQL 423
Query: 246 E 246
E
Sbjct: 424 E 424
>gi|40556370 PHD finger protein 15 [Homo sapiens]
Length = 790
Score = 138 bits (347), Expect = 3e-32
Identities = 73/175 (41%), Positives = 98/175 (56%), Gaps = 14/175 (8%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
C VC G N +V+CD C+V VHQACYGI++VPTG W CR C + +C L
Sbjct: 202 CDVCRSPEGEDGNEMVFCD--KCNVCVHQACYGILKVPTGSWLCRTC---ALGVQPKCLL 256
Query: 68 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEE 125
CP + GALK T +G W HV CAL+IPEV MEPI + ++P R+ +C +C+E
Sbjct: 257 CPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKE 316
Query: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180
+G C+ C+ C AFHVTCA GL + + D VK+ +C+ H
Sbjct: 317 -------CTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSFCQEH 364
>gi|117190334 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 137 bits (344), Expect = 7e-32
Identities = 77/175 (44%), Positives = 95/175 (54%), Gaps = 14/175 (8%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
C VC N +V+CD C+V VHQACYGI++VP G W CR C +C L
Sbjct: 203 CDVCRSPDSEEGNDMVFCD--KCNVCVHQACYGILKVPEGSWLCRSC---VLGIYPQCVL 257
Query: 68 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEE 125
CP K GALK T G WAHV CAL+IPEV A MEPI + ++P R+ C +C
Sbjct: 258 CPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC-- 315
Query: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180
K +GAC+ C+ C AFHVTCA GL + + E D VK+ YC H
Sbjct: 316 -----KLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKH 365
>gi|7662006 PHD finger protein 16 [Homo sapiens]
Length = 823
Score = 137 bits (344), Expect = 7e-32
Identities = 77/175 (44%), Positives = 95/175 (54%), Gaps = 14/175 (8%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGIVQVPTGPWFCRKCESQERAARVRCEL 67
C VC N +V+CD C+V VHQACYGI++VP G W CR C +C L
Sbjct: 203 CDVCRSPDSEEGNDMVFCD--KCNVCVHQACYGILKVPEGSWLCRSC---VLGIYPQCVL 257
Query: 68 CPHKDGALKRTDNG-GWAHVVCALYIPEVQFANVLTMEPIV-LQYVPHDRFNKTCYICEE 125
CP K GALK T G WAHV CAL+IPEV A MEPI + ++P R+ C +C
Sbjct: 258 CPKKGGALKTTKTGTKWAHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCNLC-- 315
Query: 126 QGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCGYCKYH 180
K +GAC+ C+ C AFHVTCA GL + + E D VK+ YC H
Sbjct: 316 -----KLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDEGDEVKFKSYCLKH 365
>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
Length = 888
Score = 134 bits (337), Expect = 5e-31
Identities = 67/189 (35%), Positives = 96/189 (50%), Gaps = 20/189 (10%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGI-----------VQVPTGPWFCRKCES 56
CCVC + + ++ CD C + VH+ CYG+ + T PWFC C+
Sbjct: 322 CCVCLGDNSEDADEIIQCDN--CGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKC 379
Query: 57 QERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRF 116
CELCP++DG K TD G W H+VCALY+P V F ++ + P+ L + + ++
Sbjct: 380 ---GVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKY 436
Query: 117 N-KTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCG 175
K C CE+ A +G C++C+ CR FHVTCAQ GLL E E +
Sbjct: 437 GAKECSFCED---PRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFA 493
Query: 176 YCKYHFSKM 184
YCK H ++
Sbjct: 494 YCKQHADRL 502
>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
Length = 948
Score = 134 bits (337), Expect = 5e-31
Identities = 67/189 (35%), Positives = 96/189 (50%), Gaps = 20/189 (10%)
Query: 8 CCVCSDERGWAENPLVYCDGHACSVAVHQACYGI-----------VQVPTGPWFCRKCES 56
CCVC + + ++ CD C + VH+ CYG+ + T PWFC C+
Sbjct: 322 CCVCLGDNSEDADEIIQCDN--CGITVHEGCYGVDGESDSIMSSASENSTEPWFCDACKC 379
Query: 57 QERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRF 116
CELCP++DG K TD G W H+VCALY+P V F ++ + P+ L + + ++
Sbjct: 380 ---GVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKY 436
Query: 117 N-KTCYICEEQGRESKAASGACMTCNRHGCRQAFHVTCAQMAGLLCEEEVLEVDNVKYCG 175
K C CE+ A +G C++C+ CR FHVTCAQ GLL E E +
Sbjct: 437 GAKECSFCED---PRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFA 493
Query: 176 YCKYHFSKM 184
YCK H ++
Sbjct: 494 YCKQHADRL 502
>gi|45504380 jumonji domain containing 2B [Homo sapiens]
Length = 1096
Score = 107 bits (268), Expect = 5e-23
Identities = 53/146 (36%), Positives = 79/146 (54%), Gaps = 8/146 (5%)
Query: 20 NPLVYCDGHACSVAVHQACYGI-VQVPTGPWFCRKCESQERAARVRCELCPHKDGALKRT 78
+PL+ C C + VH +CYGI ++ W C +C + A C LC + GAL+ T
Sbjct: 755 SPLIACG--KCCLQVHASCYGIRPELVNEGWTCSRCAAHAWTAE--CCLCNLRGGALQMT 810
Query: 79 DNGGWAHVVCALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACM 138
+ W HV+CA+ +PE +F NV+ P+ + +P R+ C C + K SGAC+
Sbjct: 811 TDRRWIHVICAIAVPEARFLNVIERHPVDISAIPEQRWKLKCVYCR---KRMKKVSGACI 867
Query: 139 TCNRHGCRQAFHVTCAQMAGLLCEEE 164
C+ C +FHVTCA AG+L E +
Sbjct: 868 QCSYEHCSTSFHVTCAHAAGVLMEPD 893
>gi|226442889 jumonji domain containing 2C isoform 2 [Homo sapiens]
Length = 1047
Score = 104 bits (260), Expect = 4e-22
Identities = 56/137 (40%), Positives = 75/137 (54%), Gaps = 8/137 (5%)
Query: 30 CSVAVHQACYGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVV 87
C V VH +CYGI ++ G W C +C+ A C LC + GALK+T N WAHV+
Sbjct: 721 CCVRVHASCYGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVM 777
Query: 88 CALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQ 147
CA+ +PEV+F NV I + +P R C C + K SGAC+ C+ C
Sbjct: 778 CAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHR---VKRVSGACIQCSYGRCPA 834
Query: 148 AFHVTCAQMAGLLCEEE 164
+FHVTCA AG+L E +
Sbjct: 835 SFHVTCAHAAGVLMEPD 851
Score = 30.4 bits (67), Expect = 9.6
Identities = 62/266 (23%), Positives = 95/266 (35%), Gaps = 51/266 (19%)
Query: 216 RRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVS 275
R+ R AS S Q + + K+ + D+E E P + ++K S
Sbjct: 364 RKVRKASRSFQCARSTS------KRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEK-S 416
Query: 276 SSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSS 335
+A + EAS++E S +SR + S H KLS +S S S + +
Sbjct: 417 EAAVKLRNTEASSEEESSASRMQVEQNLSDHI------KLSG----NSCLSTSVTEDIKT 466
Query: 336 SSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFE 395
+V S+ S D S P Y KP PS P +PE
Sbjct: 467 EDDKAYAYRSVPSISSEADDSI------PLSSGYEKPEKSDPSELSWPKSPE-------- 512
Query: 396 QKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPA 455
S+ S+G D +S G+G G +PA+ + +
Sbjct: 513 ------------SCSSVAESNGVLTEGEESDVES---HGNGLEPG---EIPAVPSGERNS 554
Query: 456 DETPETGLKEKKHKASKRSRHGPGRP 481
+ P + E ++K SK RH RP
Sbjct: 555 FKVP--SIAEGENKTSKSWRHPLSRP 578
>gi|109255247 jumonji domain containing 2C isoform 1 [Homo sapiens]
Length = 1056
Score = 104 bits (260), Expect = 4e-22
Identities = 56/137 (40%), Positives = 75/137 (54%), Gaps = 8/137 (5%)
Query: 30 CSVAVHQACYGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVV 87
C V VH +CYGI ++ G W C +C+ A C LC + GALK+T N WAHV+
Sbjct: 721 CCVRVHASCYGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVM 777
Query: 88 CALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQ 147
CA+ +PEV+F NV I + +P R C C + K SGAC+ C+ C
Sbjct: 778 CAVAVPEVRFTNVPERTQIDVGRIPLQRLKLKCIFCRHR---VKRVSGACIQCSYGRCPA 834
Query: 148 AFHVTCAQMAGLLCEEE 164
+FHVTCA AG+L E +
Sbjct: 835 SFHVTCAHAAGVLMEPD 851
Score = 30.4 bits (67), Expect = 9.6
Identities = 62/266 (23%), Positives = 95/266 (35%), Gaps = 51/266 (19%)
Query: 216 RRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVS 275
R+ R AS S Q + + K+ + D+E E P + ++K S
Sbjct: 364 RKVRKASRSFQCARSTS------KRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEK-S 416
Query: 276 SSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSS 335
+A + EAS++E S +SR + S H KLS +S S S + +
Sbjct: 417 EAAVKLRNTEASSEEESSASRMQVEQNLSDHI------KLSG----NSCLSTSVTEDIKT 466
Query: 336 SSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFE 395
+V S+ S D S P Y KP PS P +PE
Sbjct: 467 EDDKAYAYRSVPSISSEADDSI------PLSSGYEKPEKSDPSELSWPKSPE-------- 512
Query: 396 QKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPA 455
S+ S+G D +S G+G G +PA+ + +
Sbjct: 513 ------------SCSSVAESNGVLTEGEESDVES---HGNGLEPG---EIPAVPSGERNS 554
Query: 456 DETPETGLKEKKHKASKRSRHGPGRP 481
+ P + E ++K SK RH RP
Sbjct: 555 FKVP--SIAEGENKTSKSWRHPLSRP 578
>gi|98986459 jumonji domain containing 2A [Homo sapiens]
Length = 1064
Score = 101 bits (251), Expect = 4e-21
Identities = 48/136 (35%), Positives = 72/136 (52%), Gaps = 6/136 (4%)
Query: 30 CSVAVHQACYGIVQVPTGP-WFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVVC 88
CSV VH +CYG+ W C +C + A C LC + GAL+R ++ W HV C
Sbjct: 741 CSVRVHASCYGVPPAKASEDWMCSRCSAN--ALEEDCCLCSLRGGALQRANDDRWVHVSC 798
Query: 89 ALYIPEVQFANVLTMEPIVLQYVPHDRFNKTCYICEEQGRESKAASGACMTCNRHGCRQA 148
A+ I E +F N+ P+ + +P RF C C+ + K +G C+ C+ C A
Sbjct: 799 AVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCK---KRRKRTAGCCVQCSHGRCPTA 855
Query: 149 FHVTCAQMAGLLCEEE 164
FHV+CAQ AG++ + +
Sbjct: 856 FHVSCAQAAGVMMQPD 871
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 76.3 bits (186), Expect = 2e-13
Identities = 96/402 (23%), Positives = 142/402 (35%), Gaps = 102/402 (25%)
Query: 197 GAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQK----- 251
G G ++ G G G+RSR+ S + + P ++ + + +
Sbjct: 975 GNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPP 1034
Query: 252 ----------HKKRPESPPSILTPPV------VP---------------TADKVSSSASS 280
R ++PP + TPP+ +P T+ SS+ S
Sbjct: 1035 TSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGS 1094
Query: 281 SSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGG 340
SHH S+ +S SS + GK SS S KLSS S +S SS S +SS S G
Sbjct: 1095 KSHHSHSS--SSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGK 1152
Query: 341 PFQPAVS-------------SLQSSPDFSAFPKLEQPE-----------EDKYSKPTAPA 376
P ++ Q P P L +P DK + P P
Sbjct: 1153 PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPV 1212
Query: 377 PSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSG 436
P PPS A P + SG G S T+SSSG KS GS
Sbjct: 1213 PGTPPSSKAKSP----------ISSGSGG-SHMSGTSSSSG---------MKSSSGLGSS 1252
Query: 437 ASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKG-SRNKEG------ 489
S + K P+ ++ + +G +S +++HG + K SRNK+
Sbjct: 1253 GSL-SQKTPPSSNSCTASSSSFSSSG----SSMSSSQNQHGSSKGKSPSRNKKPSLTAVI 1307
Query: 490 --------TGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSG 523
T GP Q+ T +++ P S +S G
Sbjct: 1308 DKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGG 1349
Score = 53.5 bits (127), Expect = 1e-06
Identities = 52/184 (28%), Positives = 71/184 (38%), Gaps = 9/184 (4%)
Query: 182 SKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKS 241
SK+ +S +SS G G + S GG G + +S S+ + P
Sbjct: 1125 SKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNP 1184
Query: 242 RKDKERLKQKHKKRPESPPSILTP----PVVPTADKVSSSASSSSHHEASTQETSESSRE 297
K + H + P + +P P P + K S SS S + +S S +
Sbjct: 1185 SLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMK 1244
Query: 298 SKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSA 357
S SS SLS K S+ S S+SS SSS SS S Q SS SP +
Sbjct: 1245 SSSGLGSSGSLSQKTPPSSN----SCTASSSSFSSSGSSMSSSQNQHG-SSKGKSPSRNK 1299
Query: 358 FPKL 361
P L
Sbjct: 1300 KPSL 1303
Score = 49.3 bits (116), Expect = 2e-05
Identities = 93/391 (23%), Positives = 139/391 (35%), Gaps = 78/391 (19%)
Query: 267 VVPTADKVSSSASSSSHHEAST-----------QETSESSRESKGKKSSSHSLSHKGKKL 315
++ A K + A HH S ++T + +E G +S+ S G L
Sbjct: 933 IISVAGKALAPADLMEHHSGSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLS----GPGL 988
Query: 316 SSGKGVSSFTSASSSSSS----------------SSSSSGGPFQPAVSSLQSSPDFSAFP 359
S G S T ++ S S SSS PF P S+ S SA
Sbjct: 989 DSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSAG- 1047
Query: 360 KLEQPEEDKYSKPTAPAPSAPPSPSAP-EPPKADLFEQKVVFSGFGPIMRFSTTTSSSGR 418
T P + PP P + PK + G S TSS
Sbjct: 1048 ----------RSQTPPGVATPPIPKITIQIPKGTVM--------VGKPSSHSQYTSSGSV 1089
Query: 419 ARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGP 478
+ + S + H + S +SA T +M + + G K +S S G
Sbjct: 1090 SSSGSKSHHS--HSSSSSSSASTSGKMKS----------SKSEGSSSSKLSSSMYSSQGS 1137
Query: 479 GRPKGSRNKEGTGGP--AAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSG 536
S+N +GG ++P +G ++T P S + + LS PS
Sbjct: 1138 SGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNP--SLSKPNISPSH 1195
Query: 537 SLP---SLSLESPLL---GAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPR 590
S P S L SP+ G + K PIS G + T SS + G +
Sbjct: 1196 SRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSH-MSGTSSSSGMKSSSGLGSSGS 1254
Query: 591 LSRSPFTSTLPSSSASISTTQVFSLAGSTFS 621
LS+ T PSS++ +++ FS +GS+ S
Sbjct: 1255 LSQK----TPPSSNSCTASSSSFSSSGSSMS 1281
Score = 39.3 bits (90), Expect = 0.021
Identities = 85/351 (24%), Positives = 133/351 (37%), Gaps = 26/351 (7%)
Query: 483 GSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLS 542
GS+ T G ++ T+ S SG L S G SRT G S
Sbjct: 952 GSQGPLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKP--GKRSRTPSNDGK----S 1005
Query: 543 LESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPS 602
+ P T K P SHS + P S+ PG++ R P +T P
Sbjct: 1006 KDKPPKRKKADTEGKSP-SHSSS--NRPFTPPTSTGGSKSPGSAG--RSQTPPGVATPPI 1060
Query: 603 SSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTS 662
+I + + G PS+H T G+V+ S++ SH+ S + S
Sbjct: 1061 PKITIQIPKGTVMVGK----PSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKS 1116
Query: 663 PQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVEM 722
+ SS S +SS +++ S+ + + G + K G +G + +M
Sbjct: 1117 SKSEGSSSSKLSS--SMYSSQGSSGSSQSKNSSQSGGKPGSSPIT-KHGLS-SGSSSTKM 1172
Query: 723 LKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLP 782
N L + +++ R + +L+ P +P P++ P G
Sbjct: 1173 KPQGKPSSLMNPSLSKP--NISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSG-- 1228
Query: 783 PQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHST 833
+G S TS S KSS GL +S S S + P S S ++SS SF S+
Sbjct: 1229 --SGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSS-NSCTASSSSFSSS 1276
Score = 33.9 bits (76), Expect = 0.86
Identities = 37/142 (26%), Positives = 54/142 (38%), Gaps = 28/142 (19%)
Query: 772 NGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFH 831
+G PG + SS S ST P GK S ++ SLS + P H
Sbjct: 1149 SGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPS-------------H 1195
Query: 832 STPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGS 891
S PP + LA P P+P P + ++P ++G G M+ G + S
Sbjct: 1196 SRPP--------GGSDKLASP--MKPVPGTPPSSKAKSPISSGSGGSHMS-----GTSSS 1240
Query: 892 GGLPLNGLLGGLNGAAAPNPAS 913
G+ + LG + P S
Sbjct: 1241 SGMKSSSGLGSSGSLSQKTPPS 1262
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 74.3 bits (181), Expect = 6e-13
Identities = 165/684 (24%), Positives = 244/684 (35%), Gaps = 127/684 (18%)
Query: 225 TQQEKHPTHHERGQKKSRKD-KERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSH 283
T+Q K G+KK +E L+ + + SP + T A+K +A +
Sbjct: 3 TRQNKDSMSMRSGRKKEAPGPREELRSRGRA---SPGGVSTSSSDGKAEKSRQTAKKARV 59
Query: 284 HEASTQETSESSR-----ESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSS 338
EAST + ++ R ES+ +++++ + ++L + S S S + SS
Sbjct: 60 EEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSS 119
Query: 339 GGPFQPAVSSLQSSPDFSAFPKLEQPEEDKY------SKPTAPAPSAPPSP----SAPEP 388
P + +SP + +E + ++P P P PPSP S P
Sbjct: 120 -DPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQ 178
Query: 389 PKADLFE--QKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTG---SGASAGTHK 443
P+A FE V +G+ M T+ AP P P TG SG G K
Sbjct: 179 PEAS-FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP-K 236
Query: 444 RMPALSATPVP----ADETPETGLKEKKHKAS-KRSRHGPGRPKGSRNKEGTGGPA---- 494
A S+ P P T + AS P P G N PA
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH 296
Query: 495 -APSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPS--------GSLPSLSLES 545
P+LP A P + S GLG PS G LP +
Sbjct: 297 VTPNLP-------PPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKG 349
Query: 546 PLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSA 605
P L P HS P SSS PP R P++S+ SS+A
Sbjct: 350 PTLA---------PSPHS--------LPPASSSAPAPP--------MRFPYSSSSSSSAA 384
Query: 606 SISTTQVFSLAGSTF----SLPS-THIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRG 660
+ S++ S + S F +LPS H F P + +S +T+P L + +G
Sbjct: 385 ASSSSSSSSSSASPFPASQALPSYPHSFPPP---TSLSVSNQPPKYTQPSLPSQAVWSQG 441
Query: 661 TSPQESLSSMSPISSL-PALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNI 719
P + S+ P F P G Q P +T+
Sbjct: 442 PPPPPPYGRLLANSNAHPGPF-----PPSTGAQSTAHPPVSTHHHH-------------- 482
Query: 720 VEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFP-ALPAALPAANGPVPGP 778
H Q++ Q+ Q+Q ++++ Q + P P A P L + P
Sbjct: 483 -------HQQQQQQQQQQQQ------QQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP 529
Query: 779 YGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLP 838
Y + P G S PPG + L +S + S+ +G P SSS+ S ++ P
Sbjct: 530 YAMSPSLG-----SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584
Query: 839 LLQQSPATLPLALPGAPAPLPPQP 862
SP+ P GAP P PP P
Sbjct: 585 CSHPSPSQGP---QGAPYPFPPVP 605
Score = 50.1 bits (118), Expect = 1e-05
Identities = 95/392 (24%), Positives = 144/392 (36%), Gaps = 82/392 (20%)
Query: 322 SSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPK----LEQPEEDKYSKPTAPAP 377
SS +SA++SSSSSSSSS PA +L S P +FP + KY++P+ P+
Sbjct: 378 SSSSSAAASSSSSSSSSSASPFPASQALPSYP--HSFPPPTSLSVSNQPPKYTQPSLPSQ 435
Query: 378 SAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGA 437
+ P PP +G ++ S + P +GA
Sbjct: 436 AVWSQGPPPPPP-------------YGRLLANSNA--------------HPGPFPPSTGA 468
Query: 438 SAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPS 497
+ H P +S + + ++++ + ++ H G GP P
Sbjct: 469 QSTAH---PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHH------------GNSGPPPPG 513
Query: 498 LPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNK 557
L G ++ A P++ +S LG L GP+ LP + AG N
Sbjct: 514 AFPHPLEGGSSHHAHPYA----MSPSLGSLRPYPPGPA-HLPPPHSQVSYSQAG---PNG 565
Query: 558 DPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPF--TSTLPSSSASISTTQVFSL 615
P+S S + ST S P S P+ + PF T+ +SSA++ST + ++
Sbjct: 566 PPVSSSS---NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV-IATV 621
Query: 616 AGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLE---DCSFRC------RGTSPQES 666
A S + G P A + T P + SFR RGTSP
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG 681
Query: 667 LSSMSPISSLPALFDQTASAPCGGGQLDPAAP 698
+ P S G G L PA P
Sbjct: 682 PGTFKP-----------GSPTVGPGPLPPAGP 702
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/191 (29%), Positives = 68/191 (35%), Gaps = 16/191 (8%)
Query: 764 LPAALPAANGPVPGPYGLPPQAGSSDSLSTSKS--PPGKSSLGLDNSLSTSSEDPHSGCP 821
LP LP+ + G GLPP +L+ S PP SS S S
Sbjct: 325 LPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAA 384
Query: 822 SRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMA 881
+ SSSS S S+ P P Q ALP P PP + P ++P
Sbjct: 385 ASSSSSSS-SSSASPFPASQ--------ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQ 435
Query: 882 EGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQ 941
G P LL N P P S G T P + QQ+ Q
Sbjct: 436 AVWSQGPPPPP--PYGRLLANSNAHPGPFPPS---TGAQSTAHPPVSTHHHHHQQQQQQQ 490
Query: 942 QQEQQLQQLQQ 952
QQ+QQ QQ QQ
Sbjct: 491 QQQQQQQQQQQ 501
Score = 44.3 bits (103), Expect = 6e-04
Identities = 60/279 (21%), Positives = 96/279 (34%), Gaps = 31/279 (11%)
Query: 214 SGRRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADK 273
+G +S + P + H ++ Q++ ++ +++ +Q H PP P+
Sbjct: 466 TGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL------ 519
Query: 274 VSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSS 333
SSHH A S S + L ++S + + SSSS+S
Sbjct: 520 ----EGGSSHH-AHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNS 574
Query: 334 SSSSSGGPFQPAVSSLQSSPDFSAFP------------KLEQPEEDKYSKPTAPAPSAPP 381
SSS+S G + + S P + +P L S P ++PP
Sbjct: 575 SSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP 634
Query: 382 SP-----SAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYK--SPHVTG 434
P AP P G P R T G + PG +K SP V
Sbjct: 635 GPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGP 694
Query: 435 SGASAGTHKRMPALSATP-VPADETPETGLKEKKHKASK 472
+P+L P PA P + + K+ A +
Sbjct: 695 GPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEE 733
Score = 43.5 bits (101), Expect = 0.001
Identities = 73/310 (23%), Positives = 98/310 (31%), Gaps = 57/310 (18%)
Query: 218 SRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVS-- 275
+RS SPS P E S + + + P PPS P P + S
Sbjct: 128 NRSTSPSIYS---PGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFE 184
Query: 276 --SSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSS 333
S + + +H TS + G L G GV S
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTG-----GVLSGPPMGPKGGG 239
Query: 334 SSSSSGGPF------QPAVSSLQSSPDFSAFPKLEQPEEDKY--SKPTAPAPSAPP--SP 383
++SS GGP P SS S P + P + P+AP P+ P +P
Sbjct: 240 AASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTP 299
Query: 384 SAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSG------- 436
+ P PP P+ S S G P PG SPH G G
Sbjct: 300 NLPPPP------------ALRPLNNASA--SPPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345
Query: 437 ------ASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGT 490
+ H PA S+ P P P + AS S S + +
Sbjct: 346 PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS--------SSSSSSAS 397
Query: 491 GGPAAPSLPS 500
PA+ +LPS
Sbjct: 398 PFPASQALPS 407
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/176 (28%), Positives = 69/176 (39%), Gaps = 26/176 (14%)
Query: 762 PALPAALPAANGPV-PGPYGLPPQAGSSDSLST----SKSPPGKSSLGLDNSLSTSSEDP 816
P P P G V GP P G++ S+ + PP + + + S S +S P
Sbjct: 214 PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISV--SSSGASGAP 271
Query: 817 HSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLG 876
+ P+ + S PPP A P P P P +P N +P GLG
Sbjct: 272 PTKPPTTPVGGGNLPSAPPP--------ANFPHVTPNLPPPPALRPLNNASASP--PGLG 321
Query: 877 AMPMAEGLLGGLA---GSGGLPLNGLLGGLNGAAAPNPASL---SQAGGAPTLQLP 926
A P+ L A G GGLP G AP+P SL S + AP ++ P
Sbjct: 322 AQPLPGHLPSPHAMGQGMGGLPPGPEKG---PTLAPSPHSLPPASSSAPAPPMRFP 374
Score = 42.0 bits (97), Expect = 0.003
Identities = 79/333 (23%), Positives = 112/333 (33%), Gaps = 38/333 (11%)
Query: 764 LPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSR 823
LP+A P AN P P LPP + S SPPG + L L + PH+
Sbjct: 285 LPSAPPPANFPHVTP-NLPPPPALRPLNNASASPPGLGAQPLPGHLPS----PHA----M 335
Query: 824 SSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEG 883
P P L SP +LP A APAP P + + AA + +
Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS-- 393
Query: 884 LLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQ------- 936
+ + P + L + P P SLS + P P + Q
Sbjct: 394 -----SSASPFPASQALPSYPHSFPP-PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
Query: 937 -RHLLQQQEQQLQQL-----QQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQ 990
LL Q A P ++ H Q QQ QQ+++ Q+ Q G+
Sbjct: 448 YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNS 507
Query: 991 LPMASLLAGSSTPLLSAGTPGLLPTASAPPL-----LPAGALVAPSLGNNTSLMAAAAAA 1045
P PL + P A +P L P G P + S A
Sbjct: 508 GPPPP--GAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG 565
Query: 1046 AAVAAAGGPPVLTAQ-TNPFLSLSGAEGSGGGP 1077
V+++ T+Q + P S ++G G P
Sbjct: 566 PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAP 598
Score = 38.9 bits (89), Expect = 0.027
Identities = 158/744 (21%), Positives = 230/744 (30%), Gaps = 135/744 (18%)
Query: 214 SGRRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADK 273
SGR+ + P + G S D + K + + TP V
Sbjct: 14 SGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKV--NKQG 71
Query: 274 VSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKL----------------SS 317
S S S E + + +++ +E +S S S G+ L S+
Sbjct: 72 RSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRST 131
Query: 318 GKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTA--- 374
+ S S + S SSS S GP +P P FP QP + +P A
Sbjct: 132 SPSIYSPGSVENDSDSSSGLSQGPARP-----YHPPPL--FPPSPQPPDSTPRQPEASFE 184
Query: 375 PAPSAPPSP-SAP-EPPKADLFEQ---------KVVFSGFGPIMRFSTTTSSSGRARA-- 421
P PS P+ AP EPP + +F+ ++ G G ++ G A +
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSV 244
Query: 422 --PSPGDYKSP-----HVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRS 474
P+ G P V+ SGAS + P TPV P +
Sbjct: 245 GGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT---TPVGGGNLPSAPPPANFPHVTPNL 301
Query: 475 RHGPG-RP--KGSRNKEGTGGPAAPS---LPSAQLAGFTATAASPFSGGSLVSS--GLGG 526
P RP S + G G P P A G P G +L S L
Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361
Query: 527 LSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCS------TPLSSSLL 580
SS P P S S A +S+ + +A+ S P S S+
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVS 421
Query: 581 GPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLS 640
P P L S P S A PST T +P +S
Sbjct: 422 NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST----AHPPVS 477
Query: 641 QAESSHTEPDLEDCSFRCRGTSPQE--SLSSMSPISSLPALFDQTASAPCGG-------G 691
H + + + + Q+ S P + P + +S G
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLG 537
Query: 692 QLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQ 751
L P PG ++ + +AG N + + ++ +Q
Sbjct: 538 SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQG---------------- 581
Query: 752 ILNVQLSVPFPALPAALPA-ANGPVPGPYGLPPQ---AGSSDSLST-------------S 794
+ P + P+ + GP PY PP SS +LST +
Sbjct: 582 -----------SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKT 630
Query: 795 KSPPGKS-------SLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATL 847
SPPG S G + + P S R+ + + T PP P T
Sbjct: 631 ASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPA-----GPGTF 685
Query: 848 PLALPGA-PAPLPPQPQNGLGRAP 870
P P PLPP +GL P
Sbjct: 686 KPGSPTVGPGPLPPAGPSGLPSLP 709
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 74.3 bits (181), Expect = 6e-13
Identities = 165/684 (24%), Positives = 244/684 (35%), Gaps = 127/684 (18%)
Query: 225 TQQEKHPTHHERGQKKSRKD-KERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSH 283
T+Q K G+KK +E L+ + + SP + T A+K +A +
Sbjct: 3 TRQNKDSMSMRSGRKKEAPGPREELRSRGRA---SPGGVSTSSSDGKAEKSRQTAKKARV 59
Query: 284 HEASTQETSESSR-----ESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSS 338
EAST + ++ R ES+ +++++ + ++L + S S S + SS
Sbjct: 60 EEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSS 119
Query: 339 GGPFQPAVSSLQSSPDFSAFPKLEQPEEDKY------SKPTAPAPSAPPSP----SAPEP 388
P + +SP + +E + ++P P P PPSP S P
Sbjct: 120 -DPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQ 178
Query: 389 PKADLFE--QKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTG---SGASAGTHK 443
P+A FE V +G+ M T+ AP P P TG SG G K
Sbjct: 179 PEAS-FEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGP-K 236
Query: 444 RMPALSATPVP----ADETPETGLKEKKHKAS-KRSRHGPGRPKGSRNKEGTGGPA---- 494
A S+ P P T + AS P P G N PA
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPH 296
Query: 495 -APSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPS--------GSLPSLSLES 545
P+LP A P + S GLG PS G LP +
Sbjct: 297 VTPNLP-------PPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKG 349
Query: 546 PLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSA 605
P L P HS P SSS PP R P++S+ SS+A
Sbjct: 350 PTLA---------PSPHS--------LPPASSSAPAPP--------MRFPYSSSSSSSAA 384
Query: 606 SISTTQVFSLAGSTF----SLPS-THIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRG 660
+ S++ S + S F +LPS H F P + +S +T+P L + +G
Sbjct: 385 ASSSSSSSSSSASPFPASQALPSYPHSFPPP---TSLSVSNQPPKYTQPSLPSQAVWSQG 441
Query: 661 TSPQESLSSMSPISSL-PALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNI 719
P + S+ P F P G Q P +T+
Sbjct: 442 PPPPPPYGRLLANSNAHPGPF-----PPSTGAQSTAHPPVSTHHHH-------------- 482
Query: 720 VEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFP-ALPAALPAANGPVPGP 778
H Q++ Q+ Q+Q ++++ Q + P P A P L + P
Sbjct: 483 -------HQQQQQQQQQQQQ------QQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHP 529
Query: 779 YGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLP 838
Y + P G S PPG + L +S + S+ +G P SSS+ S ++ P
Sbjct: 530 YAMSPSLG-----SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584
Query: 839 LLQQSPATLPLALPGAPAPLPPQP 862
SP+ P GAP P PP P
Sbjct: 585 CSHPSPSQGP---QGAPYPFPPVP 605
Score = 50.1 bits (118), Expect = 1e-05
Identities = 95/392 (24%), Positives = 144/392 (36%), Gaps = 82/392 (20%)
Query: 322 SSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPK----LEQPEEDKYSKPTAPAP 377
SS +SA++SSSSSSSSS PA +L S P +FP + KY++P+ P+
Sbjct: 378 SSSSSAAASSSSSSSSSSASPFPASQALPSYP--HSFPPPTSLSVSNQPPKYTQPSLPSQ 435
Query: 378 SAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGA 437
+ P PP +G ++ S + P +GA
Sbjct: 436 AVWSQGPPPPPP-------------YGRLLANSNA--------------HPGPFPPSTGA 468
Query: 438 SAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPS 497
+ H P +S + + ++++ + ++ H G GP P
Sbjct: 469 QSTAH---PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHH------------GNSGPPPPG 513
Query: 498 LPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNK 557
L G ++ A P++ +S LG L GP+ LP + AG N
Sbjct: 514 AFPHPLEGGSSHHAHPYA----MSPSLGSLRPYPPGPA-HLPPPHSQVSYSQAG---PNG 565
Query: 558 DPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPF--TSTLPSSSASISTTQVFSL 615
P+S S + ST S P S P+ + PF T+ +SSA++ST + ++
Sbjct: 566 PPVSSSS---NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV-IATV 621
Query: 616 AGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLE---DCSFRC------RGTSPQES 666
A S + G P A + T P + SFR RGTSP
Sbjct: 622 ASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG 681
Query: 667 LSSMSPISSLPALFDQTASAPCGGGQLDPAAP 698
+ P S G G L PA P
Sbjct: 682 PGTFKP-----------GSPTVGPGPLPPAGP 702
Score = 48.5 bits (114), Expect = 3e-05
Identities = 56/191 (29%), Positives = 68/191 (35%), Gaps = 16/191 (8%)
Query: 764 LPAALPAANGPVPGPYGLPPQAGSSDSLSTSKS--PPGKSSLGLDNSLSTSSEDPHSGCP 821
LP LP+ + G GLPP +L+ S PP SS S S
Sbjct: 325 LPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAA 384
Query: 822 SRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMA 881
+ SSSS S S+ P P Q ALP P PP + P ++P
Sbjct: 385 ASSSSSSS-SSSASPFPASQ--------ALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQ 435
Query: 882 EGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQ 941
G P LL N P P S G T P + QQ+ Q
Sbjct: 436 AVWSQGPPPPP--PYGRLLANSNAHPGPFPPS---TGAQSTAHPPVSTHHHHHQQQQQQQ 490
Query: 942 QQEQQLQQLQQ 952
QQ+QQ QQ QQ
Sbjct: 491 QQQQQQQQQQQ 501
Score = 44.3 bits (103), Expect = 6e-04
Identities = 60/279 (21%), Positives = 96/279 (34%), Gaps = 31/279 (11%)
Query: 214 SGRRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADK 273
+G +S + P + H ++ Q++ ++ +++ +Q H PP P+
Sbjct: 466 TGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPL------ 519
Query: 274 VSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSS 333
SSHH A S S + L ++S + + SSSS+S
Sbjct: 520 ----EGGSSHH-AHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNS 574
Query: 334 SSSSSGGPFQPAVSSLQSSPDFSAFP------------KLEQPEEDKYSKPTAPAPSAPP 381
SSS+S G + + S P + +P L S P ++PP
Sbjct: 575 SSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP 634
Query: 382 SP-----SAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYK--SPHVTG 434
P AP P G P R T G + PG +K SP V
Sbjct: 635 GPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGP 694
Query: 435 SGASAGTHKRMPALSATP-VPADETPETGLKEKKHKASK 472
+P+L P PA P + + K+ A +
Sbjct: 695 GPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEE 733
Score = 43.5 bits (101), Expect = 0.001
Identities = 73/310 (23%), Positives = 98/310 (31%), Gaps = 57/310 (18%)
Query: 218 SRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVS-- 275
+RS SPS P E S + + + P PPS P P + S
Sbjct: 128 NRSTSPSIYS---PGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFE 184
Query: 276 --SSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSS 333
S + + +H TS + G L G GV S
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTG-----GVLSGPPMGPKGGG 239
Query: 334 SSSSSGGPF------QPAVSSLQSSPDFSAFPKLEQPEEDKY--SKPTAPAPSAPP--SP 383
++SS GGP P SS S P + P + P+AP P+ P +P
Sbjct: 240 AASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTP 299
Query: 384 SAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSG------- 436
+ P PP P+ S S G P PG SPH G G
Sbjct: 300 NLPPPP------------ALRPLNNASA--SPPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345
Query: 437 ------ASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGT 490
+ H PA S+ P P P + AS S S + +
Sbjct: 346 PEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSS--------SSSSSSAS 397
Query: 491 GGPAAPSLPS 500
PA+ +LPS
Sbjct: 398 PFPASQALPS 407
Score = 42.4 bits (98), Expect = 0.002
Identities = 51/176 (28%), Positives = 69/176 (39%), Gaps = 26/176 (14%)
Query: 762 PALPAALPAANGPV-PGPYGLPPQAGSSDSLST----SKSPPGKSSLGLDNSLSTSSEDP 816
P P P G V GP P G++ S+ + PP + + + S S +S P
Sbjct: 214 PPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISV--SSSGASGAP 271
Query: 817 HSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLG 876
+ P+ + S PPP A P P P P +P N +P GLG
Sbjct: 272 PTKPPTTPVGGGNLPSAPPP--------ANFPHVTPNLPPPPALRPLNNASASP--PGLG 321
Query: 877 AMPMAEGLLGGLA---GSGGLPLNGLLGGLNGAAAPNPASL---SQAGGAPTLQLP 926
A P+ L A G GGLP G AP+P SL S + AP ++ P
Sbjct: 322 AQPLPGHLPSPHAMGQGMGGLPPGPEKG---PTLAPSPHSLPPASSSAPAPPMRFP 374
Score = 42.0 bits (97), Expect = 0.003
Identities = 79/333 (23%), Positives = 112/333 (33%), Gaps = 38/333 (11%)
Query: 764 LPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSR 823
LP+A P AN P P LPP + S SPPG + L L + PH+
Sbjct: 285 LPSAPPPANFPHVTP-NLPPPPALRPLNNASASPPGLGAQPLPGHLPS----PHA----M 335
Query: 824 SSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEG 883
P P L SP +LP A APAP P + + AA + +
Sbjct: 336 GQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS-- 393
Query: 884 LLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQ------- 936
+ + P + L + P P SLS + P P + Q
Sbjct: 394 -----SSASPFPASQALPSYPHSFPP-PTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
Query: 937 -RHLLQQQEQQLQQL-----QQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQ 990
LL Q A P ++ H Q QQ QQ+++ Q+ Q G+
Sbjct: 448 YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNS 507
Query: 991 LPMASLLAGSSTPLLSAGTPGLLPTASAPPL-----LPAGALVAPSLGNNTSLMAAAAAA 1045
P PL + P A +P L P G P + S A
Sbjct: 508 GPPPP--GAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG 565
Query: 1046 AAVAAAGGPPVLTAQ-TNPFLSLSGAEGSGGGP 1077
V+++ T+Q + P S ++G G P
Sbjct: 566 PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAP 598
Score = 38.9 bits (89), Expect = 0.027
Identities = 158/744 (21%), Positives = 230/744 (30%), Gaps = 135/744 (18%)
Query: 214 SGRRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADK 273
SGR+ + P + G S D + K + + TP V
Sbjct: 14 SGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKV--NKQG 71
Query: 274 VSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKL----------------SS 317
S S S E + + +++ +E +S S S G+ L S+
Sbjct: 72 RSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRST 131
Query: 318 GKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTA--- 374
+ S S + S SSS S GP +P P FP QP + +P A
Sbjct: 132 SPSIYSPGSVENDSDSSSGLSQGPARP-----YHPPPL--FPPSPQPPDSTPRQPEASFE 184
Query: 375 PAPSAPPSP-SAP-EPPKADLFEQ---------KVVFSGFGPIMRFSTTTSSSGRARA-- 421
P PS P+ AP EPP + +F+ ++ G G ++ G A +
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSV 244
Query: 422 --PSPGDYKSP-----HVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRS 474
P+ G P V+ SGAS + P TPV P +
Sbjct: 245 GGPNGGKQHPPPTTPISVSSSGASGAPPTKPPT---TPVGGGNLPSAPPPANFPHVTPNL 301
Query: 475 RHGPG-RP--KGSRNKEGTGGPAAPS---LPSAQLAGFTATAASPFSGGSLVSS--GLGG 526
P RP S + G G P P A G P G +L S L
Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPP 361
Query: 527 LSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCS------TPLSSSLL 580
SS P P S S A +S+ + +A+ S P S S+
Sbjct: 362 ASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVS 421
Query: 581 GPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLS 640
P P L S P S A PST T +P +S
Sbjct: 422 NQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQST----AHPPVS 477
Query: 641 QAESSHTEPDLEDCSFRCRGTSPQE--SLSSMSPISSLPALFDQTASAPCGG-------G 691
H + + + + Q+ S P + P + +S G
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLG 537
Query: 692 QLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQ 751
L P PG ++ + +AG N + + ++ +Q
Sbjct: 538 SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQG---------------- 581
Query: 752 ILNVQLSVPFPALPAALPA-ANGPVPGPYGLPPQ---AGSSDSLST-------------S 794
+ P + P+ + GP PY PP SS +LST +
Sbjct: 582 -----------SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKT 630
Query: 795 KSPPGKS-------SLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATL 847
SPPG S G + + P S R+ + + T PP P T
Sbjct: 631 ASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPA-----GPGTF 685
Query: 848 PLALPGA-PAPLPPQPQNGLGRAP 870
P P PLPP +GL P
Sbjct: 686 KPGSPTVGPGPLPPAGPSGLPSLP 709
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 72.8 bits (177), Expect = 2e-12
Identities = 151/650 (23%), Positives = 238/650 (36%), Gaps = 151/650 (23%)
Query: 270 TADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASS 329
T+ + S SS+ H EA++ T+ + + +++ G S SSF++A +
Sbjct: 1690 TSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSR----SSFSTAKT 1745
Query: 330 SSS--SSSSSSGGPFQPAVSSLQSSPDFSAF----PKLEQPEEDKYSKPTAPAPSAPPSP 383
S+S S +SS+ P + S+ +P+ ++ P PT +PP+
Sbjct: 1746 STSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTG 1805
Query: 384 SAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHK 443
+ P S GP+ T TS P+P PH T TH
Sbjct: 1806 TTP-------------ISSTGPV----TATSFQTTTTYPTPSH---PHTT-----LPTH- 1839
Query: 444 RMPALSATPVPADETPETG---LKEKKHKASKRSRH----GPGRPKGSRNKEGTGGPAAP 496
+P+ S + V TP T + A+ S H G P + G+ A P
Sbjct: 1840 -VPSFSTSLV----TPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPP 1894
Query: 497 SLPSAQLAGFTATAASPFSGGSL-VSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTS 555
P+ + T+ SP S + S+ L +S T P + S + +P + T
Sbjct: 1895 MTPTT-----SGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS---TG 1946
Query: 556 NKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSL 615
+ P++H+ T SSS L P T+ P SPF+ST P ++ S TT +
Sbjct: 1947 TRTPVAHT---------TSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPT 1997
Query: 616 AG--------------STFSLPSTH---------------IFGTPMGAVNP--LLSQAES 644
++ PSTH I TP G V P L S
Sbjct: 1998 PSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGS 2057
Query: 645 SHTEPDLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNME 704
+HT P + + GTS ++ SS S ++ + ++ P P++P TT
Sbjct: 2058 THTAPPM---TVTTSGTS--QTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT--- 2109
Query: 705 QLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPAL 764
Q+ L++ + N QLS F
Sbjct: 2110 ----------------------------------QLPHLSSATTPVSTTN-QLSSSFSPS 2134
Query: 765 PAALPAANGPVPGPYGLP----PQAGSSDSLSTSKSPPGKSSLGLDNSLS----TSSEDP 816
P+A + VP + P P G+S S ++ S G +SLS T+S
Sbjct: 2135 PSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA 2194
Query: 817 HSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGL 866
PS ++S + +T LP SP TL LP + + P P + L
Sbjct: 2195 SPLFPSSPAASTTIRAT---LPHTISSPFTLSALLPISTVTVSPTPSSHL 2241
Score = 63.9 bits (154), Expect = 8e-10
Identities = 101/437 (23%), Positives = 159/437 (36%), Gaps = 47/437 (10%)
Query: 265 PPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSF 324
PP+ PT S S SS S + ST +S + + + + + K S+G +
Sbjct: 1893 PPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTG----TR 1948
Query: 325 TSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPS 384
T + ++S+SSS PF SSP S P + + PT P P
Sbjct: 1949 TPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPT------PSHPQ 2002
Query: 385 APEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKR 444
P F +V ++ +T T + A S P T A+ TH
Sbjct: 2003 TTLPTHVPPFSTSLVTPSTHTVI-ITTHTQMATSASIHSTPTGTVPPPTTLKATGSTH-T 2060
Query: 445 MPALSATPVPADET---------PETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAA 495
P ++ T +T + + S P P ++ +
Sbjct: 2061 APPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTP 2120
Query: 496 PSLPSAQLAGFTATAASPFSGGSLVSSGLGG--LSSRTFGPSGSLPSLSLESPLLGAGIY 553
S + + F+ + ++P + S V S SS + G S S S + S L +G +
Sbjct: 2121 VSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSH 2180
Query: 554 TS-NKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFT--STLPSSSASISTT 610
+S + P + S S+P +S+ + + LP SPFT + LP S+ ++S T
Sbjct: 2181 SSLSTHPTTASVSASPLFPSSPAASTTI----RATLPHTISSPFTLSALLPISTVTVSPT 2236
Query: 611 QVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQESLSSM 670
LA ST + PST S+HT P S R T SL++
Sbjct: 2237 PSSHLASSTIAFPSTP-------------RTTASTHTAPAFSSQSTTSRST----SLTTR 2279
Query: 671 SPISSLPALFDQTASAP 687
P S +L P
Sbjct: 2280 VPTSGFVSLTSGVTGIP 2296
Score = 56.2 bits (134), Expect = 2e-07
Identities = 101/475 (21%), Positives = 172/475 (36%), Gaps = 90/475 (18%)
Query: 256 PESPPSILTPPV---VPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKG 312
P P + +TP +P + S+A+ + +A+T+ T+ ++ S S++ S +
Sbjct: 1271 PPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTA--SPATTSTAQSTTRTT 1328
Query: 313 KKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKP 372
L T A+S +S + S P ++ Q++ +P + P
Sbjct: 1329 MTLP--------TPATSGTSPTLPKSTNQELPGTTATQTTGP--------RPTPASTTGP 1372
Query: 373 TAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHV 432
T P P P P+A E + + P +T + + + PS G V
Sbjct: 1373 TTPQPGQPTRPTATETTQTRTTTEYTT-----PQTPHTTHSPPTAGSPVPSTGP-----V 1422
Query: 433 TGSGASAGTHKRMPALSATPVPADETP-ETGLKEKKHKASKRSRHGPGRPKGSRNKEGTG 491
T + A T P+ T +P P T L H S + TG
Sbjct: 1423 TATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTG 1482
Query: 492 GPAAPSLPSAQLAGFTATAASPFSGGSLVS----------SGLGGLSSRTFGPSGSLPSL 541
P+ A + TA +P + G+ + + L +S T P + S
Sbjct: 1483 TIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST 1542
Query: 542 SLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLP 601
+ +P + T + P++H+ +SS PP T+ P SPF+ST P
Sbjct: 1543 TTITPNPTS---TRTRTPVAHTNSA---------TSSRPPPPFTTHSPPTGSSPFSSTGP 1590
Query: 602 SSSASISTTQVFSLA--------------GSTFSLPSTH---------------IFGTPM 632
++ S TT + ++ PSTH I P
Sbjct: 1591 MTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT 1650
Query: 633 GAVNP--LLSQAESSHTEPDLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTAS 685
G + P L S+HT P + + GTS ++LSS++ + +L T+S
Sbjct: 1651 GTIPPPTTLKATGSTHTAPTM---TLTTSGTS--QALSSLNTAKTSTSLHSHTSS 1700
>gi|226442893 jumonji domain containing 2C isoform 3 [Homo sapiens]
Length = 813
Score = 69.3 bits (168), Expect = 2e-11
Identities = 37/88 (42%), Positives = 50/88 (56%), Gaps = 5/88 (5%)
Query: 30 CSVAVHQACYGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVV 87
C V VH +CYGI ++ G W C +C+ A C LC + GALK+T N WAHV+
Sbjct: 721 CCVRVHASCYGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVM 777
Query: 88 CALYIPEVQFANVLTMEPIVLQYVPHDR 115
CA+ +PEV+F NV I + +P R
Sbjct: 778 CAVAVPEVRFTNVPERTQIDVGRIPLQR 805
Score = 30.4 bits (67), Expect = 9.6
Identities = 62/266 (23%), Positives = 95/266 (35%), Gaps = 51/266 (19%)
Query: 216 RRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVS 275
R+ R AS S Q + + K+ + D+E E P + ++K S
Sbjct: 364 RKVRKASRSFQCARSTS------KRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEK-S 416
Query: 276 SSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSS 335
+A + EAS++E S +SR + S H KLS +S S S + +
Sbjct: 417 EAAVKLRNTEASSEEESSASRMQVEQNLSDHI------KLSG----NSCLSTSVTEDIKT 466
Query: 336 SSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFE 395
+V S+ S D S P Y KP PS P +PE
Sbjct: 467 EDDKAYAYRSVPSISSEADDSI------PLSSGYEKPEKSDPSELSWPKSPE-------- 512
Query: 396 QKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPA 455
S+ S+G D +S G+G G +PA+ + +
Sbjct: 513 ------------SCSSVAESNGVLTEGEESDVES---HGNGLEPG---EIPAVPSGERNS 554
Query: 456 DETPETGLKEKKHKASKRSRHGPGRP 481
+ P + E ++K SK RH RP
Sbjct: 555 FKVP--SIAEGENKTSKSWRHPLSRP 578
>gi|226442897 jumonji domain containing 2C isoform 4 [Homo sapiens]
Length = 835
Score = 69.3 bits (168), Expect = 2e-11
Identities = 37/88 (42%), Positives = 50/88 (56%), Gaps = 5/88 (5%)
Query: 30 CSVAVHQACYGIV--QVPTGPWFCRKCESQERAARVRCELCPHKDGALKRTDNGGWAHVV 87
C V VH +CYGI ++ G W C +C+ A C LC + GALK+T N WAHV+
Sbjct: 743 CCVRVHASCYGIPSHEICDG-WLCARCK--RNAWTAECCLCNLRGGALKQTKNNKWAHVM 799
Query: 88 CALYIPEVQFANVLTMEPIVLQYVPHDR 115
CA+ +PEV+F NV I + +P R
Sbjct: 800 CAVAVPEVRFTNVPERTQIDVGRIPLQR 827
Score = 30.4 bits (67), Expect = 9.6
Identities = 62/266 (23%), Positives = 95/266 (35%), Gaps = 51/266 (19%)
Query: 216 RRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVS 275
R+ R AS S Q + + K+ + D+E E P + ++K S
Sbjct: 386 RKVRKASRSFQCARSTS------KRPKADEEEEVSDEVDGAEVPNPDSVTDDLKVSEK-S 438
Query: 276 SSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSS 335
+A + EAS++E S +SR + S H KLS +S S S + +
Sbjct: 439 EAAVKLRNTEASSEEESSASRMQVEQNLSDHI------KLSG----NSCLSTSVTEDIKT 488
Query: 336 SSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFE 395
+V S+ S D S P Y KP PS P +PE
Sbjct: 489 EDDKAYAYRSVPSISSEADDSI------PLSSGYEKPEKSDPSELSWPKSPE-------- 534
Query: 396 QKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPA 455
S+ S+G D +S G+G G +PA+ + +
Sbjct: 535 ------------SCSSVAESNGVLTEGEESDVES---HGNGLEPG---EIPAVPSGERNS 576
Query: 456 DETPETGLKEKKHKASKRSRHGPGRP 481
+ P + E ++K SK RH RP
Sbjct: 577 FKVP--SIAEGENKTSKSWRHPLSRP 600
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 66.2 bits (160), Expect = 2e-10
Identities = 74/237 (31%), Positives = 95/237 (40%), Gaps = 30/237 (12%)
Query: 227 QEKHP--THHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHH 284
QE P T + G KS DK + +Q + ES S + SSS+SSSS
Sbjct: 2527 QEPGPGLTFEDSGNPKS-PDKAQAEQDGAEESESSSSS------SSGSSSSSSSSSSSGS 2579
Query: 285 EASTQETSE-----------------SSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSA 327
E +E + SSR + SSS S S SS SS +S+
Sbjct: 2580 ETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS 2639
Query: 328 SSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPE 387
SSSSSSSSSSS + SS SS S+ ++ APAP+A PS A
Sbjct: 2640 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAAL 2699
Query: 388 PPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKR 444
P KA K S P + T + +A P P P +GA + KR
Sbjct: 2700 PTKATKQAGKARPSAHSPGKK---TPAPQPQAPPPQPTQPLQPKAQ-AGAKSRPKKR 2752
Score = 48.5 bits (114), Expect = 3e-05
Identities = 93/447 (20%), Positives = 147/447 (32%), Gaps = 48/447 (10%)
Query: 257 ESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLS 316
E P++L P + K S + E + +G+K S+ + + L
Sbjct: 2290 EPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLE 2349
Query: 317 SGKGVSSFTSA--SSSSSSSSSSSGGPFQPAVSSL----------QSSPDFSAFPKLEQP 364
G S + SS+ S P +P Q SP AF P
Sbjct: 2350 EGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAP 2409
Query: 365 EEDKYSKPTAPAPSAPPSP------SAPEPPKADLFEQKVVFSGFGP---------IMRF 409
E +++ APA S P+P + P+P KA E+ P +
Sbjct: 2410 EP--FAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHE 2467
Query: 410 STTTSSSGRARA-------PSPGDYKSPHVTGS-----GASAGTHKRMPALSATPVPADE 457
T+ S +A+ P G ++ P S A+ + + P AT +
Sbjct: 2468 GVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQ 2527
Query: 458 TPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGG 517
P GL + K G+ E + ++ S S+ + + + G
Sbjct: 2528 EPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEG 2587
Query: 518 SLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSS 577
+G GG T G + S S SP A +S+ S S + S+ SS
Sbjct: 2588 D--KNGDGGCG--TGGRNCSAASSRAASP---ASSSSSSSSSSSSSSSSSSSSSSSSSSS 2640
Query: 578 SLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNP 637
S +S+ S S +S+ SSS+S STT S S G A P
Sbjct: 2641 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALP 2700
Query: 638 LLSQAESSHTEPDLEDCSFRCRGTSPQ 664
+ ++ P + PQ
Sbjct: 2701 TKATKQAGKARPSAHSPGKKTPAPQPQ 2727
Score = 41.2 bits (95), Expect = 0.005
Identities = 92/375 (24%), Positives = 124/375 (33%), Gaps = 57/375 (15%)
Query: 695 PAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILN 754
P PG T E EA N+VE K L+KE + + S + Q L
Sbjct: 1040 PPTPGITRKE---------EAPENVVE--KKDLELEKEAPSPFQALFSDIPPRYPFQALP 1088
Query: 755 VQLSVPFPAL--PAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTS 812
P+P L P A A+G P LP +LS P S + L
Sbjct: 1089 PHYGRPYPFLLQPTAAADADGLAPD-VPLPADGPERLALSPEDKPIRLSPSKITEPLREG 1147
Query: 813 SEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGA 872
E+ + P LP L+ PL LP A A P P G G
Sbjct: 1148 PEEEPLAEREVKAEVEDMDEGPTELPPLES-----PLPLPAAEAMATPSPAGGCG----- 1197
Query: 873 AGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSL 932
GGL + L G A P+ G P + PG
Sbjct: 1198 -------------GGLLEAQALSATG-----QSCAEPSECPDFVEGPEPRVDSPGRTEPC 1239
Query: 933 TEQQRHLLQ-QQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQM------ 985
T +Q E ++ ++ + P P + V + + Q+ L+M
Sbjct: 1240 TAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTLEMSDCDVP 1299
Query: 986 AGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGNNTSLMAAAAAA 1045
AG Q P SL + P+L G+ L AS+ LP +L P G N +AAAA
Sbjct: 1300 AGEGQCP--SLEPQEAVPVL--GSTCFLEEASSDQFLP--SLEDPLAGMNA--LAAAAEL 1351
Query: 1046 AAVAAAGGPPVLTAQ 1060
P AQ
Sbjct: 1352 PQARPLPSPGAAGAQ 1366
Score = 41.2 bits (95), Expect = 0.005
Identities = 59/248 (23%), Positives = 84/248 (33%), Gaps = 50/248 (20%)
Query: 182 SKMKTSRHSSG----GGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG 237
S +S SSG G G G G G GG S SR+ASP++ +
Sbjct: 2568 SSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN-CSAASSRAASPASSSSSSSSSSSSS 2626
Query: 238 QKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRE 297
S S S ++ SSS+SSSS +S+ T++
Sbjct: 2627 SSSSSSSSSSSSSSSSSSSSSSSS--------SSSSSSSSSSSSSSSSSSSSSTTDED-- 2676
Query: 298 SKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGP-FQPAVSSLQSSPDFS 356
+S SS ++ + + GP Q A+ + +
Sbjct: 2677 ---------------------------SSCSSDDEAAPAPTAGPSAQAALPTKATKQAGK 2709
Query: 357 AFPKLEQPEEDKYSKPTAPAPSA-PPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSS 415
A P P + K AP P A PP P+ P PKA + G + TT
Sbjct: 2710 ARPSAHSPGK----KTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREG--VHLPTTKEL 2763
Query: 416 SGRARAPS 423
+ R R PS
Sbjct: 2764 AKRQRLPS 2771
Score = 34.7 bits (78), Expect = 0.51
Identities = 148/634 (23%), Positives = 219/634 (34%), Gaps = 92/634 (14%)
Query: 420 RAPSPGDYKSPHVTGSGASAGTHKRMPALS-----ATPVPADETPETGLKEKKHKASKRS 474
+ P P D +P V + AS +PA A P P + P +A+K
Sbjct: 437 KRPPPAD--APTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQAAKLF 494
Query: 475 RHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTA----------TAASPFSGGSLVSSGL 524
PGRP + + + + Q+A A A S
Sbjct: 495 GLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHSRAEEEAAVVAASSSKKAYLDP 554
Query: 525 GGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLR-AVCSTPLSSSLLGPP 583
G + R+ G P + S G+G ++ + I +SG R AV P P
Sbjct: 555 GAVLPRSAATCGR-PVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPF 613
Query: 584 GTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAE 643
G + +P +SA S Q LP H G G L E
Sbjct: 614 GGLGTMKPEPAP-------TSAGASRAQA--------RLP--HSGGPAAGGGRQLKRDPE 656
Query: 644 SSHTEPDLEDCSFRCRGTSPQ-ESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTN 702
+ +F G+ Q E+ P+ A+ Q S G G+L P
Sbjct: 657 RPESAK-----AFGREGSGAQGEAEVRHPPVGIAVAVARQKDSG--GSGRLGPGLVDQER 709
Query: 703 MEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFP 762
L +G G A + V+ +A H +E++L +++ ++L +
Sbjct: 710 SLSLSNVKGHGRADEDCVDD-RARHR--------EERLLGARLDRDQEKLLRESKEL--- 757
Query: 763 ALPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPS 822
A L + P GL P + + + S G+ S L+T P SG
Sbjct: 758 ---ADLARLHPTSCAPNGLNPNLMVTGGPALAGS--GRWSADPAAHLATHPWLPRSG--- 809
Query: 823 RSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAE 882
+S L+ H P L Q A P PG LP Q R P + L +P
Sbjct: 810 NASMWLAGHPYGLGPPSLHQGMA--PAFPPGLGGSLPSAYQ--FVRDPQSGQLVVIP--- 862
Query: 883 GLLGGLAGSGGLPLNGLLGGLNGAAAPN------PASLSQAGGAPTLQLPGCLNSLTEQQ 936
S LP L + A P P S A LQL + L +Q+
Sbjct: 863 --------SDHLPHFAEL--MERATVPPLWPALYPPGRSPLHHAQQLQLFSQQHFLRQQE 912
Query: 937 RHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASL 996
LQQQ Q +LQ+ S QL E + + ++++K + L+ AG + L A
Sbjct: 913 FLYLQQQAAQALELQR---SAQLVQE-RLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGP 968
Query: 997 -LAGSSTPLLSAGTPGLLPTASAPPLLPAGALVA 1029
L P L+AG G A +PP P + VA
Sbjct: 969 GLLPRKPPGLAAGPAGTYGKAVSPPPSPRASPVA 1002
Score = 32.3 bits (72), Expect = 2.5
Identities = 61/248 (24%), Positives = 91/248 (36%), Gaps = 38/248 (15%)
Query: 368 KYSKPTAPAPSAPPSPSAPE---PPKADLFEQKVVFSGFGPIMRFSTTTSSSG-RARAPS 423
+++ P+P+ PS S + KA E++ G F T S S + R S
Sbjct: 1870 RFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLG----TEFEYTDSESEVKVRKRS 1925
Query: 424 PGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSR-----HGP 478
P P G + P+L+A P P P+ +K A ++ R GP
Sbjct: 1926 PAGLLRP-------KKGLGEPGPSLAA-PTPGARGPDPSSPDKAKLAVEKGRKARKLRGP 1977
Query: 479 GRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSL 538
P E + S ++ A+AA+P + VS+ +SR G L
Sbjct: 1978 KEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAP----APVSTAPATKTSRC-AKGGPL 2032
Query: 539 PSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTS 598
SP AG KDP G + L PP ALP +R+P S
Sbjct: 2033 ------SPRKDAGRAKDRKDPRKKKKGKEAG------PGAGLPPPRAPALPSEARAPHAS 2080
Query: 599 TLPSSSAS 606
+L ++ S
Sbjct: 2081 SLTAAKRS 2088
Score = 30.4 bits (67), Expect = 9.6
Identities = 34/143 (23%), Positives = 55/143 (38%), Gaps = 30/143 (20%)
Query: 235 ERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSES 294
+ G+ K RKD ++K K + P + L PP P + + + + H +S S
Sbjct: 2037 DAGRAKDRKDP---RKKKKGKEAGPGAGLPPPRAP-----ALPSEARAPHASSLTAAKRS 2088
Query: 295 SRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPD 354
++KGK+ KK + GKG + S S ++ F+P S S +
Sbjct: 2089 KAKAKGKEV---------KKENRGKG------GAVSKLMESMAAEEDFEPNQDSSFSEDE 2133
Query: 355 FSAFPKLEQPEEDKYSKPTAPAP 377
P +P PAP
Sbjct: 2134 -------HLPRGGAVERPLTPAP 2149
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 65.1 bits (157), Expect = 3e-10
Identities = 177/842 (21%), Positives = 293/842 (34%), Gaps = 137/842 (16%)
Query: 258 SPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSS 317
SPPS T PV + S S+ + H ++ TS S +S ++ H S
Sbjct: 2232 SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS--------TIFHSSPDASG 2283
Query: 318 GKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAP-- 375
++ +SA S++S S+ P + + + P + P L + YS P +P
Sbjct: 2284 ----TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 2339
Query: 376 --APSAPPSPSAPEPPKADLFEQKVVFSGFGP-------IMRFSTTTSSSGRARAPSPGD 426
+P++ S E + S P + STT SS +
Sbjct: 2340 TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVF 2399
Query: 427 YKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRN 486
++P + G T PA + T + +++ +GL E+ S PG P ++
Sbjct: 2400 PRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE-------STAFPGSPASTQ- 2451
Query: 487 KEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLSLESP 546
TG PA +L +A L + T S SSG G + P+ S S
Sbjct: 2452 ---TGLPA--TLTTADLGEESTTFPS--------SSGSTGTTLS--------PARSTTSG 2490
Query: 547 LLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTS-TLPSSSA 605
L+G + R S+ +++L G P T +L S + +TS P ++
Sbjct: 2491 LVGESTPS-------------RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATL 2537
Query: 606 SISTTQ---VFSLAGSTFSLP-STHIFGTPMGAVNPLLSQ-AESSHTEPDLED-----CS 655
S +TT V + ++ S P STH P P LS+ + +SH+ P D S
Sbjct: 2538 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 2597
Query: 656 FRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDP--AAPGTTNMEQLLEKQGDG 713
G S + + S SP S+ AL + +A G + ++PG+T+ D
Sbjct: 2598 TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF----PDS 2653
Query: 714 EAGVNIVEMLKALHA------------------LQKENQRLQEQILS--LTAKKERLQIL 753
IVE +H+ LQ E+ Q S T
Sbjct: 2654 TTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATA 2713
Query: 754 NVQLSVPFPALPAALPAANGPV-----------------PGPYGLPPQAGSSDSLSTSKS 796
V+ S + P + P + P P G P + S + +S
Sbjct: 2714 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2773
Query: 797 PPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPA 856
+ S G S ++ + P S +S +F+S+P +SP T P +
Sbjct: 2774 TTSRISPG---STEITTLPGSTTTPGLSEASTTFYSSP-------RSPTT--TLSPASMT 2821
Query: 857 PLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQ 916
L ++ R+ + + A GL+ + G P + S
Sbjct: 2822 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSV 2881
Query: 917 AGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQL-QQLLASPQLTPEHQTVVYQMIQQIQ 975
G PT +S L ++ L ++ A P QT + +
Sbjct: 2882 RGEEPT-----TFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD 2936
Query: 976 QKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGNN 1035
E + GS S +++ L+ TP L +S G+ PSL
Sbjct: 2937 LGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEK 2996
Query: 1036 TS 1037
++
Sbjct: 2997 ST 2998
Score = 62.4 bits (150), Expect = 2e-09
Identities = 139/644 (21%), Positives = 229/644 (35%), Gaps = 95/644 (14%)
Query: 257 ESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHS--LSHKGKK 314
ES S P T S SA+S E T + +S E+ S+ + LS K
Sbjct: 223 ESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTT 282
Query: 315 LSSGKGVSSFT---SASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSK 371
S T + ++SS S S+ +P + + PD + P + Q +S
Sbjct: 283 FYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSI 342
Query: 372 PTAPAPSAPPSPSAPEP--PKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSP--GDY 427
P + + P + P P++ F G+ R T++SG A +P
Sbjct: 343 PGSTDTTLSPGTTTPSSLGPESTTFHSS---PGYTKTTRLPDNTTTSGLLEASTPVHSST 399
Query: 428 KSPHVTGSGASAGTHKRMP-ALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRN 486
SPH T S +S+ TH+ P + P D +P P +
Sbjct: 400 GSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSP-----------------APSGTTSAFV 442
Query: 487 KEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLSLESP 546
K T ++PS ++P + S S+ LG T S + + + P
Sbjct: 443 KLSTTYHSSPS-------------STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPP 489
Query: 547 LLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSAS 606
A + H P SS+ G SA S + S+ PS++A+
Sbjct: 490 ARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAA 549
Query: 607 ISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQES 666
++ T S GST +TH ++ ++++SH+ PD + G++P
Sbjct: 550 LAHTSYHSSLGST---ETTHF--RDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVL 604
Query: 667 L--SSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLK 724
+ S+ SPISS G A PG+T L EK + +
Sbjct: 605 VGDSTPSPISS--------------GSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTH 650
Query: 725 ALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAA-NGPVPGPYGLPP 783
++ + E+ + ++ S P L A+ + P P L P
Sbjct: 651 LPASMTSSG--VSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP 708
Query: 784 QAGSSDSL----STSKSPPGKSSLGL--DNS-----------LSTSSEDPH-----SGCP 821
+ ++ SL +T S PG + L DN+ + +S+ PH +G
Sbjct: 709 GSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGST 768
Query: 822 SRSSSSLSFHSTPPPLPLLQQSPATLPLALP------GAPAPLP 859
+R S +FHS P P T + G+P+ +P
Sbjct: 769 TRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIP 812
Score = 57.4 bits (137), Expect = 7e-08
Identities = 158/724 (21%), Positives = 249/724 (34%), Gaps = 144/724 (19%)
Query: 219 RSASPSTQQEKHPTHHERGQKKSR------KDKERLKQKHKKRPESPPSILT--PPVVPT 270
R+ + S + E+ T H R L ++ P SP S T P + T
Sbjct: 2401 RTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 2460
Query: 271 AD--KVSSSASSSSHHEASTQETSES--------SRESKGKKSSSHSLSHKGKKLS---S 317
AD + S++ SSS +T + S S S+ SS+ + + G + S
Sbjct: 2461 ADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLS 2520
Query: 318 GKGVSSFTSASS-----------SSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEE 366
K + +TS S SS S SS QP + + PD + P L +
Sbjct: 2521 EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHST 2580
Query: 367 DKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRA-RAPSPG 425
+S P + + P+ + GP +T+ SS G A SPG
Sbjct: 2581 TSHSSPGSTDTTLLPASTTTS----------------GPSQESTTSHSSPGSTDTALSPG 2624
Query: 426 DYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSR 485
S G + T P + T + D T +G+ E AS R G P+
Sbjct: 2625 ---STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE----ASTRVHSSTGSPR--- 2674
Query: 486 NKEGTGGPAAPSLPSAQLAGFT---------------ATAASPFSGGSLVSSGLGGLSSR 530
T PA+ + P Q T +TA +P + G +
Sbjct: 2675 ---TTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 2731
Query: 531 TFGPSGSLPSLSLESPLLGAGIYTSNKDPIS-HSGGMLRAVCST----PLSSSLLGPPGT 585
F S + S +S + + S P S HS R +T P S+ + PG+
Sbjct: 2732 HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 2791
Query: 586 SALPRLS----------RSPFTSTLPSSSASI--------------STTQVFSLAGST-- 619
+ P LS RSP T+ P+S S+ ST S A +T
Sbjct: 2792 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTP 2851
Query: 620 -FSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQESLSSMSPISSLPA 678
S ST ++ + G+ + ++ + E +F R S +L + S+
Sbjct: 2852 GLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTL--FTEDSTTSG 2909
Query: 679 LFDQTASAPCGGGQLDPAAPGTTNMEQLLEK-----QGDGEAGVNIVEMLKALHALQKEN 733
L +++ + P P T L E+ G G + L E+
Sbjct: 2910 LTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGES 2969
Query: 734 --QRLQEQILSLTAKKERLQILNV-QLSVPFPALPAALPAANGPVPGPYGLPPQAGSSDS 790
RL T ++ + S F P + A P +G S+
Sbjct: 2970 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP-----ATTTSSGVSEE 3024
Query: 791 LSTSKSPPGKS-SLGLDNSLSTS--SEDPHSGCPSRSSS-----------------SLSF 830
STS S PG + + +S +TS S++P + S+ S+ S +F
Sbjct: 3025 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTF 3084
Query: 831 HSTP 834
HS+P
Sbjct: 3085 HSSP 3088
Score = 55.5 bits (132), Expect = 3e-07
Identities = 162/689 (23%), Positives = 235/689 (34%), Gaps = 109/689 (15%)
Query: 256 PESPPSILTPP------VVPTADKVSSSASSSSHHEASTQETS---ESSRESKGKKSSSH 306
P S + PP V P+ S +S + H ++ TS E S S+
Sbjct: 781 PSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 840
Query: 307 SLSHKGKKLSSGKGVSSFTSASSSSS--SSSSSSGGPFQPAVSSLQSSPDFSA---FPKL 361
++ +SG+G S TS SS++ SS+ S+ +S SSP +A FP
Sbjct: 841 TMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFP-- 898
Query: 362 EQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFS-TTTSSSGRAR 420
+ S+ + + S+ + P + S PI S TT+ G
Sbjct: 899 DSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTT 958
Query: 421 AP--------------SPGDYKSP-HVTGSGAS--AGTHKRMPALSATPVPADETPETGL 463
P SP SP T SG S + T + P + T D T GL
Sbjct: 959 TPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGL 1018
Query: 464 KEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSG 523
+H + S G T GP+ S S +G T TA SP GS +
Sbjct: 1019 --SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSP---GSTTALS 1073
Query: 524 LGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPP 583
G S+ GS + +GI ++ S +G + +P SS+ G
Sbjct: 1074 FGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL--SPASSTSPGLQ 1131
Query: 584 GTS-ALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTH---------------I 627
G S A S T+ P S+A+ + + S S P+TH I
Sbjct: 1132 GESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 1191
Query: 628 F--------GTPMGAVNPLLSQAES-----------------SHTEPDLEDCSFRCRGTS 662
F TP A + + ES S T P L + S +S
Sbjct: 1192 FHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY-SS 1250
Query: 663 PQESLSSMSPIS--SLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEK--------QGD 712
P+ +++SP S SL + T S G +P +T L E+ +G
Sbjct: 1251 PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGS 1310
Query: 713 GEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNV-QLSVPFPALPAA---- 767
E V ++H + + T E + + S FP PA+
Sbjct: 1311 TETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTG 1370
Query: 768 LPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHS--------- 818
LPA SS S T SP ++ GL + S P S
Sbjct: 1371 LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 1430
Query: 819 -GCPSRSSSSLSFHSTPPPLPLLQQSPAT 846
PS S S +F+ T P P SPAT
Sbjct: 1431 PTTPSLSEKSTTFY-TSPRSPDATLSPAT 1458
Score = 55.1 bits (131), Expect = 4e-07
Identities = 148/675 (21%), Positives = 233/675 (34%), Gaps = 113/675 (16%)
Query: 258 SPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSS 317
SPPS T PV + S S+ + H ++ TS S +S ++ H S
Sbjct: 1149 SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS--------TIFHSSPDASG 1200
Query: 318 GKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAP-- 375
++ +SA S++S S+ P + + + P + P L + YS P +P
Sbjct: 1201 ----TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 1256
Query: 376 --APSAPPSPSAPEPPKADLFEQKVVFSGFGP-------IMRFSTTTSSSGRARAPSPGD 426
+P++ S E + S P + STT SS R +
Sbjct: 1257 TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVF 1316
Query: 427 YKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRN 486
S + G T PA + T + +++ +GL E+ S PG P ++
Sbjct: 1317 PHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEE-------STAFPGSPASTQ- 1368
Query: 487 KEGTGGPA----------APSLPSAQLAGFTATAASPFSGGSLVSSGLGGLS-------- 528
TG PA + + PS+ +G T T SP +SGL G S
Sbjct: 1369 ---TGLPATLTTADLGEESTTFPSS--SGSTGTKLSP---ARSTTSGLVGESTPSRLSPS 1420
Query: 529 ---SRTFGPSGSLPSLSLESPLLGAGIYTSNKDP-------ISHSGGMLRAVC---STPL 575
+ T S + PSLS +S YTS + P + S G+ S P
Sbjct: 1421 STETTTLPGSPTTPSLSEKS----TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG 1476
Query: 576 SSSLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAV 635
S+ P ++ LS+ P TS S ++ +T S S+ ST +P
Sbjct: 1477 STHTTAFPDSTTTSDLSQEPTTSH-SSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTE 1535
Query: 636 NPLLSQAESSHTEPDLEDCSFRCRGTSPQESL-----SSMSPISSLPALFDQ---TASAP 687
LL PD S ++P S ++++P SS A + T +
Sbjct: 1536 TTLL---------PDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSW 1586
Query: 688 CGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLT-AK 746
P+ PGTT VE+ H+ S T +
Sbjct: 1587 PSSSDTTPSPPGTTAAP---------------VEVSTTYHSRPSSTPTTHFSASSTTLGR 1631
Query: 747 KERLQILNVQLSVPFPALPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLD 806
E ++ AL A + V P P +GS++ T+ P ++ GL
Sbjct: 1632 SEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTE---TTALPGSTTTAGLS 1688
Query: 807 NSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSP-ATLPLALPGAPA-PLPPQPQN 864
+T P S + S +S + P +T A PG+ P Q
Sbjct: 1689 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQEST 1748
Query: 865 GLGRAPGAAGLGAMP 879
+PG+ P
Sbjct: 1749 ASHSSPGSTDTTLSP 1763
Score = 53.5 bits (127), Expect = 1e-06
Identities = 152/713 (21%), Positives = 236/713 (33%), Gaps = 80/713 (11%)
Query: 259 PPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSG 318
P S T P PT S++SH S+ T+ S S S S + +++
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452
Query: 319 KGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPS 378
S S +S S++ P + P+ + +S T S
Sbjct: 3453 TTPSPARSTTSGLVEESTTYHS--SPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS 3510
Query: 379 APPSPSAPEPPKADLFEQKVVF---SGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGS 435
AP + SA L E+ + G F ++++SGR+ S + S TG+
Sbjct: 3511 APSTTSA-------LVEEPTSYHSSPGSTATTHFPDSSTTSGRSE-ESTASHSSQDATGT 3562
Query: 436 -------------GASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPK 482
G S + ++ T +P T GL EK S P P
Sbjct: 3563 IVLPARSTTSVLLGESTTSPISSGSMETTALPG-STTTPGLSEK----STTFHSSPRSPA 3617
Query: 483 GSRNKEGT--GGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPS 540
+ + T G + S S G T T A P S + GL S+ + GS +
Sbjct: 3618 TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP---DSTTTPGLSRHSTTSHSSPGSTDT 3674
Query: 541 LSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLS-RSPFTST 599
L + +G +S + SHS +P S++ L S S S T+
Sbjct: 3675 TLLPASTTTSG--SSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 3732
Query: 600 LPSSSASI----STTQVFSLAGS--TFSLPSTHIFGTPMGAVNPLLSQAESSHTEPD--- 650
P S+ S ++T+V S GS T P++ G + S+HT P
Sbjct: 3733 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 3792
Query: 651 -----LEDCS--FRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTN- 702
+E+ + R G++P + S S S+P G +A TT+
Sbjct: 3793 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 3852
Query: 703 -MEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPF 761
E + G + + L + + S T + ++ +
Sbjct: 3853 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE- 3911
Query: 762 PALPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCP 821
+ P + P S +S + S PG + + +T+S
Sbjct: 3912 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTS-------- 3963
Query: 822 SRSSSSLSFHSTPPP--LPLLQQSPATLPL-----ALPGAPAPLPPQPQNGLGRAPGAAG 874
R +FHS P L + T L A PG+PA Q GL A
Sbjct: 3964 VRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA----STQTGLPATLTTAD 4019
Query: 875 LGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPG 927
LG G G+ P GL G + P+ S S T LPG
Sbjct: 4020 LGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPS---STETTTLPG 4069
Score = 53.1 bits (126), Expect = 1e-06
Identities = 151/739 (20%), Positives = 239/739 (32%), Gaps = 144/739 (19%)
Query: 210 SGFISGRRSRSASPSTQQEKH----PTHHERGQKKSRKDKERLKQKHKKRPESPPSILTP 265
SG + + +SP + Q H T RG++ + S PS +
Sbjct: 823 SGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTI-----SSAPSTTSA 877
Query: 266 PVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFT 325
V SS S+++ H + TS S ES SS + G
Sbjct: 878 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDAT-----------GTIVLP 926
Query: 326 SASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPP---- 381
+ S++S S+ P + P + P L + +S P +PA + P
Sbjct: 927 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 986
Query: 382 ----------SPSAPEPPKADLFEQKVVFSGF--------------------------GP 405
S S P F G GP
Sbjct: 987 SSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 1046
Query: 406 IMRFSTTTSSSGRA-RAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLK 464
+T+ SSSG A SPG S G + T P + T + D T +G+
Sbjct: 1047 SQESTTSHSSSGSTDTALSPG---STTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIV 1103
Query: 465 EKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSA---------QLAGFTATAASPFS 515
E AS R G P+ + + + P +A +TA +P
Sbjct: 1104 E----ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 1159
Query: 516 GGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPIS-HSGGMLRAVCST- 573
+ G + F S + S +S + + S P S HS R +T
Sbjct: 1160 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTS 1219
Query: 574 ---PLSSSLLGPPGTSALPRLS----------RSPFTSTLPSSSASI------------- 607
P S+ + PG++ P LS RSP T+ P+S S+
Sbjct: 1220 RISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQP 1279
Query: 608 -STTQVFSLAGST---FSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSP 663
ST S A +T S ST ++ + G+ + ++ + E +F R S
Sbjct: 1280 GSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAST 1339
Query: 664 QESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEK-----QGDGEAGVN 718
+L + S+ L +++ + P P T L E+ G G
Sbjct: 1340 HTTL--FTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTK 1397
Query: 719 IVEMLKALHALQKEN--QRLQEQILSLTAKKERLQILNV-QLSVPFPALPAALPAANGPV 775
+ L E+ RL T ++ + S F P + A P
Sbjct: 1398 LSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP- 1456
Query: 776 PGPYGLPPQAGSSDSLSTSKSPPGKS-SLGLDNSLSTS--SEDPHSGCPSRSSS------ 826
+G S+ STS S PG + + +S +TS S++P + S+ S+
Sbjct: 1457 ----ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSP 1512
Query: 827 -----------SLSFHSTP 834
S +FHS+P
Sbjct: 1513 GSTTASSLGQQSTTFHSSP 1531
Score = 52.8 bits (125), Expect = 2e-06
Identities = 149/680 (21%), Positives = 225/680 (33%), Gaps = 96/680 (14%)
Query: 256 PESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKL 315
P SP + L+P T+ VS +S+S ST T+ + S + SH +
Sbjct: 1447 PRSPDATLSPATT-TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGS 1505
Query: 316 SSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAP 375
+ T+ASS S++ P + L PD + L + +S +
Sbjct: 1506 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLL---PDDTITSGLVEASTPTHSSTGSL 1562
Query: 376 APSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGS 435
+ P+ S A L E+ F + SSS +P PG +P
Sbjct: 1563 HTTLTPASST----SAGLQEESTTFQSW---------PSSSDTTPSP-PGTTAAP----V 1604
Query: 436 GASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAA 495
S H R S+TP T L + + S G + T
Sbjct: 1605 EVSTTYHSRP---SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG 1661
Query: 496 PSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTS 555
S +G T T A P GS ++GL S TF S P +L SP S
Sbjct: 1662 EPTTSPISSGSTETTALP---GSTTTAGLSE-KSTTFYSSPRSPDTTL-SPASTTSSGVS 1716
Query: 556 NKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSL 615
+ SH S P S+ PG++ +P +S+ T++ S ++ +T S
Sbjct: 1717 EESTTSH---------SRPGSTHTTAFPGSTTMPGVSQES-TASHSSPGSTDTTLSPGST 1766
Query: 616 AGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQESL-----SSM 670
S+ ST +P LL PD S ++P S +++
Sbjct: 1767 TASSLGPESTTFHSSPGSTETTLL---------PDNTTASGLLEASTPVHSSTGSPHTTL 1817
Query: 671 SPISSLPALFDQTA--SAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHA 728
SP S + T S P + PA P TT+ VE+ H
Sbjct: 1818 SPAGSTTRQGESTTFQSWPSSKDTM-PAPPTTTSA---------------FVELSTTSHG 1861
Query: 729 LQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLPPQAGSS 788
S T + + V S P A P P
Sbjct: 1862 SPSSTPTTHFSASSTTLGRSE-ESTTVHSS----------PVATATTPSPARSTTSGLVE 1910
Query: 789 DSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLP 848
+S + SP ++ S ST+S S SS++ + S P L + P +
Sbjct: 1911 ESTAYHSSPGSTQTMHFPES-STASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYH 1969
Query: 849 LALPGAPAPLP-PQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAA 907
+ PG+ A P GR+ + + A G + LP L G +
Sbjct: 1970 -SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI-------VLPARSTTSVLLGES 2021
Query: 908 APNPASLSQAGGAPTLQLPG 927
+P S +G T LPG
Sbjct: 2022 TTSPIS---SGSMETTALPG 2038
Score = 52.8 bits (125), Expect = 2e-06
Identities = 150/713 (21%), Positives = 235/713 (32%), Gaps = 80/713 (11%)
Query: 259 PPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSG 318
P S T P PT S++SH S+ T+ S S S S + +++
Sbjct: 1836 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 1895
Query: 319 KGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPS 378
S + S++S S+ P + P+ S + +S T S
Sbjct: 1896 TTPS--PARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS 1953
Query: 379 APPSPSAPEPPKADLFEQKVVF---SGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGS 435
P + SA L E+ + G F ++++SGR+ S + S TG+
Sbjct: 1954 PPSTTSA-------LVEEPTSYHSSPGSTATTHFPDSSTTSGRSE-ESTASHSSQDATGT 2005
Query: 436 -------------GASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPK 482
G S + ++ T +P T GL EK S P P
Sbjct: 2006 IVLPARSTTSVLLGESTTSPISSGSMETTALPG-STTTPGLSEK----STTFHSSPRSPA 2060
Query: 483 GSRNKEGT--GGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPS 540
+ + T G + S S G T T A P S + GL S+ + GS +
Sbjct: 2061 TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP---DSTTTPGLSRHSTTSHSSPGSTDT 2117
Query: 541 LSLESPLLGAGIYTSNKDPISHSG-GMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTST 599
L + +G S + SHS G S +++L ++ S T+
Sbjct: 2118 TLLPASTTTSG--PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTL 2175
Query: 600 LPSSSASI----STTQVFSLAGS--TFSLPSTHIFGTPMGAVNPLLSQAESSHTEPD--- 650
P S+ S ++T+V S GS T P++ G + S+HT P
Sbjct: 2176 FPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 2235
Query: 651 -----LEDCS--FRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTN- 702
+E+ + R G++P + S S S+P G +A TT+
Sbjct: 2236 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG 2295
Query: 703 -MEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPF 761
E + G + + L + + S T + ++ +
Sbjct: 2296 RGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE- 2354
Query: 762 PALPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCP 821
+ P + P S +S + S PG + + T+S
Sbjct: 2355 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTS-------- 2406
Query: 822 SRSSSSLSFHSTPPP--LPLLQQSPATLPL-----ALPGAPAPLPPQPQNGLGRAPGAAG 874
R +FHS P L + T L A PG+PA Q GL A
Sbjct: 2407 VRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA----STQTGLPATLTTAD 2462
Query: 875 LGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPG 927
LG G G+ P GL G + P+ S S T LPG
Sbjct: 2463 LGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPS---STETTTLPG 2512
Score = 51.6 bits (122), Expect = 4e-06
Identities = 149/680 (21%), Positives = 223/680 (32%), Gaps = 96/680 (14%)
Query: 256 PESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKL 315
P SP + L+P T+ VS +S+S ST T+ + S + SH +
Sbjct: 3004 PRSPDATLSPATT-TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGS 3062
Query: 316 SSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAP 375
+ T+ASS S++ P + L PD + L + +S +
Sbjct: 3063 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLL---PDDTITSGLVEASTPTHSSTGSL 3119
Query: 376 APSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGS 435
+ P+ S A L E+ F + SSS +P PG +P
Sbjct: 3120 HTTLTPASST----SAGLQEESTTFQSW---------PSSSDTTPSP-PGTTAAP----V 3161
Query: 436 GASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAA 495
S H R S+TP T L + + S G + T
Sbjct: 3162 EVSTTYHSRP---SSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG 3218
Query: 496 PSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTS 555
S +G T T A P GS ++GL S TF S P +L SP S
Sbjct: 3219 EPTTSPISSGSTETTALP---GSTTTAGLSE-KSTTFYSSPRSPDTTL-SPASTTSSGVS 3273
Query: 556 NKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSL 615
+ SH S P S+ PG++ +P +S+ T++ S ++ +T S
Sbjct: 3274 EESTTSH---------SRPGSTHTTAFPGSTTMPGVSQES-TASHSSPGSTDTTLSPGST 3323
Query: 616 AGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQESL-----SSM 670
S+ ST P LL PD S ++P S +++
Sbjct: 3324 TASSLGPESTTFHSGPGSTETTLL---------PDNTTASGLLEASTPVHSSTGSPHTTL 3374
Query: 671 SPISSLPALFDQTA--SAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHA 728
SP S + T S P PA P TT+ VE+ H
Sbjct: 3375 SPAGSTTRQGESTTFQSWP-NSKDTTPAPPTTTSA---------------FVELSTTSHG 3418
Query: 729 LQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLPPQAGSS 788
S T + + V S P A P P
Sbjct: 3419 SPSSTPTTHFSASSTTLGRSE-ESTTVHSS----------PVATATTPSPARSTTSGLVE 3467
Query: 789 DSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLP 848
+S + SP ++ S +TS S S SS++ + S P L + P +
Sbjct: 3468 ESTTYHSSPGSTQTMHFPESDTTSGRGEES-TTSHSSTTHTISSAPSTTSALVEEPTSYH 3526
Query: 849 LALPGAPAPLP-PQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAA 907
+ PG+ A P GR+ + + A G + LP L G +
Sbjct: 3527 -SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI-------VLPARSTTSVLLGES 3578
Query: 908 APNPASLSQAGGAPTLQLPG 927
+P S +G T LPG
Sbjct: 3579 TTSPIS---SGSMETTALPG 3595
Score = 50.8 bits (120), Expect = 7e-06
Identities = 195/924 (21%), Positives = 299/924 (32%), Gaps = 200/924 (21%)
Query: 275 SSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHK----GKKLSSGKGVSSFTSASSS 330
SS S+ + H + S S ESK SS +++ G S G S+ + SS
Sbjct: 557 SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSG 616
Query: 331 SSSSSSSSGGPFQPAVS-------SLQSSPDFSAFPK------LEQPEEDKYSKPTAPAP 377
S +++ G +P +S S SPD + P + + +S+P +
Sbjct: 617 SMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHT 676
Query: 378 SAPP--------------SPSAPEPPKADLFEQKVVFSGFGP---------------IMR 408
+A P S S+P P L S GP ++
Sbjct: 677 TAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLP 736
Query: 409 FSTTTSSSGRARAPSPGDYKSPHVTGSGASAGT--------HKRMPALSATPVPADET-- 458
+TT S A P +SPH T S A + T H + P P T
Sbjct: 737 DNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSA 796
Query: 459 ---PET---------------------GLKEK-----KHKASKRSRHGPGRPKGS-RNKE 488
P T GL E+ S ++ H P S R +E
Sbjct: 797 FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 856
Query: 489 GTGG--------PAAPSLPSAQLAGFTATAASPFSGGSL---VSSGLGGLSSRTFGPSGS 537
T +APS SA + T+ +SP S + SS G S + S
Sbjct: 857 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 916
Query: 538 --------LPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALP 589
LP+ S S LLG S PIS SG M PG++ P
Sbjct: 917 QDATGTIVLPARSTTSVLLG----ESTTSPIS-SGSM-----------ETTALPGSTTTP 960
Query: 590 RLS----------RSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLL 639
LS RSP T+ P+S+ S ++ + + S STH P P L
Sbjct: 961 GLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPG--STHTTAFPDSTTTPGL 1018
Query: 640 SQ-AESSHTEPDLEDCSFRCRGTS----PQESLSSMSPISSLPALFDQTASAPCGGGQLD 694
S+ + +SH+ P D + T+ QES +S S S ++ GQ
Sbjct: 1019 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQES 1078
Query: 695 P---AAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHA------------------LQKEN 733
+ PG+T+ D IVE +H+ LQ E+
Sbjct: 1079 TTFHSNPGSTHTTLF----PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 1134
Query: 734 QRLQEQILS--LTAKKERLQILNVQLSVPFPALPAALPAANGPV---------------- 775
Q S T V+ S + P + P + P
Sbjct: 1135 TAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHS 1194
Query: 776 -PGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHSTP 834
P G P + S + +S + S G S ++ + P S +S +F+S+P
Sbjct: 1195 SPDASGTTPSSAHSTTSGRGESTTSRISPG---STEITTLPGSTTTPGLSEASTTFYSSP 1251
Query: 835 PPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGL 894
+SP T P + L ++ R+ + + A GL+
Sbjct: 1252 -------RSPTT--TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTT 1302
Query: 895 PLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQL-QQL 953
+ G P+ + S G PT +S L ++ L ++
Sbjct: 1303 VYSSSRGSTETTVFPHSTTTSVHGEEPT-----TFHSRPASTHTTLFTEDSTTSGLTEES 1357
Query: 954 LASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLL 1013
A P QT + + E + GS S +++ L+ TP L
Sbjct: 1358 TAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRL 1417
Query: 1014 PTASAPPLLPAGALVAPSLGNNTS 1037
+S G+ PSL ++
Sbjct: 1418 SPSSTETTTLPGSPTTPSLSEKST 1441
Score = 50.8 bits (120), Expect = 7e-06
Identities = 137/621 (22%), Positives = 222/621 (35%), Gaps = 112/621 (18%)
Query: 258 SPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSS 317
SPPS T PV + S S+ + H ++ TS S +S ++ H S
Sbjct: 3789 SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS--------TIFHSSPDASG 3840
Query: 318 GKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAP 377
++ +SA S++S S+ P + + + P + P L + YS P +P
Sbjct: 3841 ----TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT 3896
Query: 378 S-APPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTT----SSSGRARAPSPGDYKS--- 429
+ +P S ++ + + S + STTT S + SPG ++
Sbjct: 3897 TLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVF 3956
Query: 430 PHVTGSGA---SAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRN 486
P T + T PA + T + +++ +GL E+ S PG P ++
Sbjct: 3957 PRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEE-------STAFPGSPASTQ- 4008
Query: 487 KEGTGGPA----------APSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSG 536
TG PA + + PS+ +G T T SP +SGL G S+ PS
Sbjct: 4009 ---TGLPATLTTADLGEESTTFPSS--SGSTGTKLSP---ARSTTSGLVGEST----PSR 4056
Query: 537 SLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPF 596
PS + + L G+ S + ST +S P T SP
Sbjct: 4057 LSPSSTETTTLPGSPTTPSLSEK------------STTFYTSPRSPDAT-------LSPA 4097
Query: 597 TSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSF 656
T+T SS S ++ S GST + T + P S + TE L S
Sbjct: 4098 TTT--SSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGST 4155
Query: 657 RCRGTSPQESLSSMSPISSLPALF-DQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEA 715
Q + SP + L D T ++ G ++ + P G
Sbjct: 4156 TASSLGQQSTTFHSSPGDTETTLLPDDTITS----GLVEASTP---------THSSTGSL 4202
Query: 716 GVNIVEMLKALHALQKENQRLQEQILS--LTAKKERLQILNVQLSVPFPALPAALPAANG 773
+ LQ+E+ Q S T + V++S + + P++ P +
Sbjct: 4203 HTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHF 4262
Query: 774 PVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGCPSRSSSSLSFHST 833
G S+ +T S PG + L P+RS++S+
Sbjct: 4263 SASS-----TTLGRSEESTTVHSSPGATGTAL--------------FPTRSATSV-LVGE 4302
Query: 834 PPPLPLLQQSPATLPLALPGA 854
P P+ S +T ALPG+
Sbjct: 4303 PTTSPI--SSGSTETTALPGS 4321
Score = 48.9 bits (115), Expect = 3e-05
Identities = 129/646 (19%), Positives = 217/646 (33%), Gaps = 73/646 (11%)
Query: 256 PESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKL 315
P SP + L+P T+ VS +S+S ST T+ + S + SH +
Sbjct: 4087 PRSPDATLSPATT-TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGS 4145
Query: 316 SSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSK---P 372
+ T+ASS S++ P + L S + P
Sbjct: 4146 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 4205
Query: 373 TAPAPSA---------------PPSPSAPEPPKADLFEQKVVFS-----GFGPIMRFSTT 412
PA S S + P PP +V + P FS +
Sbjct: 4206 LTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSAS 4265
Query: 413 TSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASK 472
+++ GR+ S + SP TG+ P SAT V E + + S
Sbjct: 4266 STTLGRSE-ESTTVHSSPGATGTAL-------FPTRSATSVLVGEPTTSPIS----SGST 4313
Query: 473 RSRHGPG-RPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRT 531
+ PG +++ T ++P P L+ + T++ + S G + +
Sbjct: 4314 ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTA 4373
Query: 532 FGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRL 591
F S ++P +S ES A + + S G A P S++ PG++ L
Sbjct: 4374 FPSSTTMPGVSQEST---ASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLL 4430
Query: 592 SRSPFTSTL-----PSSSASISTTQVFSLAGSTFSLPSTHIFGT----------PMGAVN 636
+ S L P S++ S S AGST + F + P +
Sbjct: 4431 PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 4490
Query: 637 PLLSQAESSHTEPDLE-----DCSFRCRGTSPQESLSSMSPI--SSLPALFDQTASAPCG 689
+ + +SH P S G S + + SP+ ++ P+ T S
Sbjct: 4491 AFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE 4550
Query: 690 GGQLDPAAPGTTNMEQLLEK---QGDG-EAGVNIVEMLKALHALQKENQRLQEQILSLTA 745
++PG+T E G G E+ + + + L E+ S +
Sbjct: 4551 ESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHS 4610
Query: 746 KKERLQILNVQLSVPFPALPAALPAANG--PVPGPYGLPPQAGSSDSLSTSKSPPGKSSL 803
+ S A++ G LP ++ +S L S + P S
Sbjct: 4611 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS-- 4668
Query: 804 GLDNSLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPL 849
S+ T++ + P S S +FHS+P P S ++ L
Sbjct: 4669 ---GSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTL 4711
Score = 47.8 bits (112), Expect = 6e-05
Identities = 116/486 (23%), Positives = 181/486 (37%), Gaps = 78/486 (16%)
Query: 276 SSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSS--S 333
++A++ S ++T E S S+ ++ +SG+G S TS SS++ S
Sbjct: 4533 ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTIS 4592
Query: 334 SSSSSGGPFQPAVSSLQSSPDFSA---FPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPK 390
S+ S+ +S SSP +A FP + S+ + + S+ + P
Sbjct: 4593 SAPSTTSALVEEPTSYHSSPGSTATTHFP--DSSTTSGRSEESTASHSSQDATGTIVLPA 4650
Query: 391 ADLFEQKVVFSGFGPIMRFST-TTSSSGRARAP-----------SPGDYKSPHVTGSGAS 438
+ S PI S TT+ G P SP + H + S +
Sbjct: 4651 RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTT 4710
Query: 439 AGTHKRMPALSATPVPADETPE------TGLKEKK-----HKASKRSRHGP------GRP 481
G + + ++PV TP +GL E+ S ++ H P GR
Sbjct: 4711 LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRS 4770
Query: 482 KGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLV------SSGLGGLSSRTFGPS 535
+ SR + S PS A + S GS+ SS G S + S
Sbjct: 4771 EESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTA-S 4829
Query: 536 GSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSP 595
S P + +PL A TS + S + + T L+S T+ P LS
Sbjct: 4830 HSSPDTNGITPL-PAHFTTSGRIAESTTFYISPGSMETTLAS-------TATTPGLSAK- 4880
Query: 596 FTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEP------ 649
++ L SSS S T S S+ S+ I G P L SQAES+HT
Sbjct: 4881 -STILYSSSRSPDQTL------SPASMTSSSISGEPTS----LYSQAESTHTTAFPASTT 4929
Query: 650 ----DLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTASAPCG--GGQLDPAAPGTTNM 703
E +F + P + +++SP S + F Q + P G L +P +T +
Sbjct: 4930 TSGLSQESTTFH---SKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTV 4986
Query: 704 EQLLEK 709
L E+
Sbjct: 4987 PGLSEE 4992
Score = 47.0 bits (110), Expect = 1e-04
Identities = 197/951 (20%), Positives = 309/951 (32%), Gaps = 172/951 (18%)
Query: 228 EKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEAS 287
E T+H R + ES +P TA + SA+S E +
Sbjct: 1605 EVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT 1664
Query: 288 TQETSESSRESKGKKSSSHS--LSHKGKKL-SSGKGVSSFTSASSSSSS--SSSSSGGPF 342
T S S E+ S+ + LS K SS + + S +S++SS S S+
Sbjct: 1665 TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 1724
Query: 343 QPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEP--PKADLFEQKVVF 400
+P + + P + P + Q +S P + + P + P++ F
Sbjct: 1725 RPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG- 1783
Query: 401 SGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHK--------------RMP 446
S ++ +TT S A P SPH T S A + T + MP
Sbjct: 1784 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1843
Query: 447 A------------------------------------------LSATPVPADETPE---- 460
A + ++PV TP
Sbjct: 1844 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 1903
Query: 461 --TGLKEK-----KHKASKRSRHGP------GRPKGSRNKEGTGGPAAPSLPSAQLA--- 504
+GL E+ S ++ H P GR + SR + S PS A
Sbjct: 1904 TTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVE 1963
Query: 505 ---------GFTATAASPFSGGSLVSSGLGGLSSRTFGPSGS--LPSLSLESPLLGAGIY 553
G TAT P S + S S + +G+ LP+ S S LLG
Sbjct: 1964 EPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLG---- 2019
Query: 554 TSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVF 613
S PIS SG M +T L S P + SP + S AS +++ V
Sbjct: 2020 ESTTSPIS-SGSME----TTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 2074
Query: 614 SLAGSTFSLP-STHIFGTPMGAVNPLLSQ-AESSHTEPDLED-----CSFRCRGTSPQES 666
+ ++ S P STH P P LS+ + +SH+ P D S G S + +
Sbjct: 2075 EESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 2134
Query: 667 LSSMSPISSLPALFDQTASAPCGGGQLDP--AAPGTTNMEQLLEKQGDGEAGVNIVEMLK 724
S SP S+ AL + +A G + ++PG+T+ D IVE
Sbjct: 2135 TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF----PDSTTSSGIVEAST 2190
Query: 725 ALHA------------------LQKENQRLQEQILS--LTAKKERLQILNVQLSVPFPAL 764
+H+ LQ E+ Q S T V+ S +
Sbjct: 2191 RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRS 2250
Query: 765 PAALPAANGPV-----------------PGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDN 807
P + P + P P G P + S + +S + S G
Sbjct: 2251 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG--- 2307
Query: 808 SLSTSSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLG 867
S ++ + P S +S +F+S+P +SP T P + L ++
Sbjct: 2308 STEITTLPGSTTTPGLSEASTTFYSSP-------RSPTT--TLSPASMTSLGVGEESTTS 2358
Query: 868 RAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPG 927
R+ + + A GL+ + G P + S G PT
Sbjct: 2359 RSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPT----- 2413
Query: 928 CLNSLTEQQRHLLQQQEQQLQQL-QQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMA 986
+S L ++ L ++ A P QT + + E +
Sbjct: 2414 TFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS 2473
Query: 987 GGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVAPSLGNNTS 1037
GS S +++ L+ TP L +S G+ PSL ++
Sbjct: 2474 SGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 2524
Score = 46.6 bits (109), Expect = 1e-04
Identities = 104/475 (21%), Positives = 165/475 (34%), Gaps = 35/475 (7%)
Query: 228 EKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEAS 287
E T+H R + ES +P TA + SA+S E +
Sbjct: 3162 EVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT 3221
Query: 288 TQETSESSRESKGKKSSSHS--LSHKGKKL-SSGKGVSSFTSASSSSSS--SSSSSGGPF 342
T S S E+ S+ + LS K SS + + S +S++SS S S+
Sbjct: 3222 TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 3281
Query: 343 QPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEP--PKADLFEQKVVF 400
+P + + P + P + Q +S P + + P + P++ F
Sbjct: 3282 RPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH----- 3336
Query: 401 SGFGP----IMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHK-RMPALSATPVPA 455
SG G ++ +TT S A P SPH T S A + T + + P
Sbjct: 3337 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSK 3396
Query: 456 DETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFS 515
D TP + HG + + + S S + A+ S
Sbjct: 3397 DTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 3456
Query: 516 GGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPL 575
+SGL S+ GS ++ +G + SHS + S P
Sbjct: 3457 PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG--RGEESTTSHS-STTHTISSAPS 3513
Query: 576 SSSLL--------GPPGTSALPRLSRSPFTS-----TLPSSSASISTTQVFSLAGSTFSL 622
++S L PG++A S TS + S S+ +T + A ST S+
Sbjct: 3514 TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 3573
Query: 623 PSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCS--FRCRGTSPQESLSSMSPISS 675
+P+ + + + S T P L + S F SP +LS S SS
Sbjct: 3574 LLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSS 3628
Score = 46.6 bits (109), Expect = 1e-04
Identities = 133/651 (20%), Positives = 214/651 (32%), Gaps = 50/651 (7%)
Query: 228 EKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEAS 287
E T+H R + ES +P TA + SA+S E +
Sbjct: 4245 EVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT 4304
Query: 288 TQETSESSRESKGKKSSSHS--LSHKGKKL-SSGKGVSSFTSASSSSSS--SSSSSGGPF 342
T S S E+ S+ + LS K SS + + S +S++SS S S+
Sbjct: 4305 TSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 4364
Query: 343 QPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEP--PKADLFEQKVVF 400
+P + P + P + Q +S P + + P + P++ F
Sbjct: 4365 RPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPG- 4423
Query: 401 SGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHK-RMPALSATPVPADETP 459
S ++ +TT S A P SPH T S A + T + + P D TP
Sbjct: 4424 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 4483
Query: 460 ETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSL 519
+ HG + + + S S + A+ S
Sbjct: 4484 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARS 4543
Query: 520 VSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSL 579
+SGL S+ GS ++ +G + SHS + S P ++S
Sbjct: 4544 TTSGLVEESTTYHSSPGSTQTMHFPESNTTSG--RGEESTTSHS-STTHTISSAPSTTSA 4600
Query: 580 L--------GPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTP 631
L PG++A S TS S + ++Q A T LP+
Sbjct: 4601 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD---ATGTIVLPARSTTSVL 4657
Query: 632 MGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGG 691
+G S S E S G S + + SP SS P +S G
Sbjct: 4658 LG--ESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSP-SSTPTTHFSASSTTLGRS 4714
Query: 692 Q------LDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTA 745
+ P A TT G +VE A H+ Q + S +
Sbjct: 4715 EESTTVHSSPVATATTPSPARSTTSG-------LVEESTAYHSSPGSTQTMHFPESSTAS 4767
Query: 746 KKERLQILNVQLSVPFPALPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGL 805
+ + + + P + +A P Y P + ++ S + G+S
Sbjct: 4768 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSE--- 4824
Query: 806 DNSLSTSSEDPHSGCP--------SRSSSSLSFHSTPPPLPLLQQSPATLP 848
+++ S SS D + P R + S +F+ +P + S AT P
Sbjct: 4825 ESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTP 4875
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 64.3 bits (155), Expect = 6e-10
Identities = 166/726 (22%), Positives = 261/726 (35%), Gaps = 133/726 (18%)
Query: 312 GKKLSSGKGVSSFTSASSSSSSSSSSS----GGPFQPAVSSLQSSPDFSAFPKLEQPEED 367
G S KG + +A+ S S + G P PAV+ P P L
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP----PSPKGTPTLPATTPS 1355
Query: 368 KYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSP-GD 426
PT P+ P+P A P GP M T S PSP GD
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKG-----------GPAM---TPPSPKRGPAIPSPKGD 1401
Query: 427 YKSPHVTGSGASAGTHKRMPAL------SATPVPADETPE--TGLKEKKHKASKRSRHGP 478
SP V + K+ PA +ATP D TP T + KK A+ + GP
Sbjct: 1402 PTSPAVIPL-----SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456
Query: 479 GRP--KGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSG 536
P KG P+ P+ + AT++SP + T P G
Sbjct: 1457 ATPSSKGDPTLPAVTPPSPKEPPAPKQ---VATSSSPKK------------APATPAPMG 1501
Query: 537 --SLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRS 594
+LP++ SP +S +DPI+ + +L L+ P +P ++
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561
Query: 595 PFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDC 654
P T + A+ S+ + S T PST+ GA +P + T P ++
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVT---PSTY-----KGAPSPKELLIPPAVTSPSPKEA 1613
Query: 655 SFRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGE 714
T P +P AP G P P + +
Sbjct: 1614 PTPPAVTPPSPEKGPATP-------------APKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Query: 715 AGVNIVEMLKALHALQKENQRLQE----------QILSLTAKKERLQILNVQLSVPFPAL 764
G + + K L A +K L+E I++ +K + S P
Sbjct: 1661 MGATVPQASKGLPA-KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPD 1719
Query: 765 PAALPAANGPV----PGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHSGC 820
P+A + GP+ P P LP Q S SK+ GK + S S + P +
Sbjct: 1720 PSAKNGSKGPLSTVAPAPL-LPVQKDS------SKTAKGKDA-------SHSPKGPLAPP 1765
Query: 821 PSRSSSSLSFHSTPPPLPLLQQSPATL----PLALPGAPAPLP--PQPQNGLGRAPG-AA 873
S++S+ L+ + LP + + + P++LP AP+P+P P Q L +PG
Sbjct: 1766 ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVL 1825
Query: 874 GLGAMPMAEG-------LLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLP 926
+ P+A L+ SGG+P +L + P P S P+ + P
Sbjct: 1826 ESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNM-----PTPKSAGIPVPTPSAKQP 1880
Query: 927 GCLN-------SLTEQQRHLLQQQE--QQLQQLQQLLASPQLTPEHQTVVYQMIQQIQQK 977
N S +++ L++Q+ Q Q QL A+ ++ E + Q + + +
Sbjct: 1881 VTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKAR 1940
Query: 978 RELQRL 983
+ + +L
Sbjct: 1941 KAMSKL 1946
Score = 62.4 bits (150), Expect = 2e-09
Identities = 158/660 (23%), Positives = 220/660 (33%), Gaps = 104/660 (15%)
Query: 256 PESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKS-SSHSLSHKGKK 314
PE P S+ +P + P + H ++ + S +E + S +S + S KG
Sbjct: 728 PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787
Query: 315 L-----SSGKGVSSFTSASSSSSSSSSSSGGPFQPA--VSSLQSSPDFSAFPKLE---QP 364
S GVS S + + S GP P +SS S + S P+ Q
Sbjct: 788 TYLADSPSPLGVS--VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG 845
Query: 365 EEDKYS---KPTAPAPSAPPSPSAPEP--PKADLFEQK---------VVFSGFGPIM--- 407
+D + PT P+P P+PSA P PK K + F GP
Sbjct: 846 SKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905
Query: 408 ----RFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGL 463
S T+SS +ARA +P G AS P+ P P TP +
Sbjct: 906 KQAPALSMTSSSPKKARA-------TPAPKGIPAS-------PSPKGAPTPPAATPPS-- 949
Query: 464 KEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSG 523
K A+ + P P + GGPA PS P AT SP GG S
Sbjct: 950 -PKGGPATPSPKWAP-TPPAATPPSPKGGPATPS-PKGAPTPPAATPPSP-KGGPATPSP 1005
Query: 524 LGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPP 583
G + P P SP ++ P + + +TPL G P
Sbjct: 1006 KGAPT-----PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK---GAP 1057
Query: 584 GTSA--LPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAV----NP 637
T A LP P T +L + + T G P G PM +P
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK----GAPMPPAATPPSP 1113
Query: 638 LLSQAESSH----TEPDLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQL 693
A H T P S + +P + +P ++ P+ A+ P G
Sbjct: 1114 KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT 1173
Query: 694 DPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQIL 753
PAA + L G L + + + T +
Sbjct: 1174 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK---- 1229
Query: 754 NVQLSVPFPALPAALPAANGPVP--GPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLST 811
L+ P P PAA P P GP PP+ + +PP + L L+T
Sbjct: 1230 -GGLATPSPKGAPTTPAATPPSPKGGPATPPPKG--------APTPPAATPPSLKGGLAT 1280
Query: 812 SSEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATL-PLALPGAPAPLPPQPQNGLGRAP 870
PH G P+ + PP P + PAT P P PA PP P+ G P
Sbjct: 1281 ---PPHKGAPNPA-------VVTPPSP--KGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328
Score = 60.8 bits (146), Expect = 7e-09
Identities = 150/709 (21%), Positives = 230/709 (32%), Gaps = 92/709 (12%)
Query: 256 PESPPSILTPPV-VPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKK 314
P SP + PP PT V+ + ++ S S K + + + KG
Sbjct: 872 PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP 931
Query: 315 LS-SGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPT 373
S S KG + + +++ S GGP P SP ++ P P K P
Sbjct: 932 ASPSPKG-----APTPPAATPPSPKGGPATP-------SPKWAPTPPAATPPSPK-GGPA 978
Query: 374 APAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVT 433
P+P P+P A PP G + + A P P +P
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP--- 1035
Query: 434 GSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGP 493
A+ + K PA + P A TP L K + S G P + GGP
Sbjct: 1036 -PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 494 AAPSLPSAQLAGFTATAASPFSG-------------GSLVSSGLGGLSSRTFGPSGSLPS 540
A PS A + AT SP G + S GGL++ + + P+
Sbjct: 1095 ATPSPKGAPMPP-AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 541 LSLESPLLGAGI-------YTSNKDPISHSGGML----RAVCSTPLSSSLLGPPGTSALP 589
+ SP G T P S GG+ + +TP +++ P G A P
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGLATP 1212
Query: 590 RLSRSPFT--STLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHT 647
+P T +T PS ++T S P+T P P + + T
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATP-------SPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265
Query: 648 EPDLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLL 707
P S + +P + + + P+ A++P G PAA
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA---------T 1316
Query: 708 EKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAA 767
G G + A+ + + + + T + P P PAA
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP--PAA 1374
Query: 768 LPAANGPVPGPYGLPPQAGSSDSLSTSK-SPPGKSSLGLDNSLSTSSEDPHSGCPSRSSS 826
P+ G GP PP ++ + K P + + L + ++ G + S
Sbjct: 1375 TPSHKG---GPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKG 1431
Query: 827 SLSFHSTPPPLP--LLQQSPA-----------------TLPLALPGAPAPLPPQPQNGLG 867
L TPP + L+++PA TLP P +P P Q
Sbjct: 1432 DL----TPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487
Query: 868 RAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQ 916
+P A PM L + S + AP LS+
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536
Score = 51.2 bits (121), Expect = 5e-06
Identities = 177/771 (22%), Positives = 256/771 (33%), Gaps = 141/771 (18%)
Query: 223 PSTQQEKHPTHHERGQKKSRKDKERLKQKHKKRPESP----------PSILTPPVVPTAD 272
PS+ K PT +KD + + + P SP P++L P+V A
Sbjct: 519 PSSVLVKFPT---------QKDLQTVPASLEGAPFSPAQAGLTTKKDPTVL--PLVQAAP 567
Query: 273 KVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSS 332
K S S S+S S+ E S + KKS G+ L GK SS TS +S
Sbjct: 568 KNSPSFQSTS----SSPEIPLSPEATLAKKSL-------GEPLPIGKPASSMTSPLGVNS 616
Query: 333 SSS----SSSGGPFQ--PAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAP 386
S+S S GP P + S +P +AFP LE + P AP+ S
Sbjct: 617 SASVIKTDSYAGPDSAGPLLKSSLITPTVAAFP-LESAD------PAGVAPTTAKGTSTY 669
Query: 387 EPPKADLFEQKVVFSGFG-PIMRFSTTT------SSSGRARAPSPGDYKSPHVTGSGASA 439
+ E V + P+ + TT +S APSP + +P T A
Sbjct: 670 TTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA-- 727
Query: 440 GTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLP 499
P + + VP+ P G K S P S KE + S
Sbjct: 728 ------PEIPKS-VPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASAT 780
Query: 500 SAQLAGFTATAASPFSGGSLVS----------------SGLGGLSS------RTFGPSGS 537
++ T A SP G VS + +G LSS +F P S
Sbjct: 781 ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS 840
Query: 538 LPSL-SLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPF 596
L S +SP T + P S G TP + + L P G + P+ + +P
Sbjct: 841 LSFQGSKDSPAT-----THSPTPPSPKGA------PTPSAVTPLSPKGVTLPPKETPTPS 889
Query: 597 TSTLP---SSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLED 653
LP A+ + Q +L+ ++ S P G P + + T P
Sbjct: 890 VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI--PASPSPKGAPTPPAATP 947
Query: 654 CSFRCRGTSPQESLSSMSPISSLPALFDQTAS-APCG-------------GGQLDPAAPG 699
S + +P + P ++ P+ A+ +P G GG P+ G
Sbjct: 948 PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 700 TTNMEQLLEKQGDGE-AGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLS 758
+ G A + A + + L +
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA----T 1063
Query: 759 VPFPALPAALPAANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDNSLSTSSEDPHS 818
+P P A P+ G P PP + + K P + + + PH
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHK 1123
Query: 819 GCPSRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAM 878
G P+ +++ P P L P P P PA PP P+ GL P G
Sbjct: 1124 GAPTTPAAT-----PPSPKGGLATPP---PKGAPTTPAATPPSPKGGLA-TPPPKGAPTT 1174
Query: 879 PMA--EGLLGGLA-----GSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPT 922
P A GGLA G+ P G A P+P GAPT
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK------GAPT 1219
Score = 51.2 bits (121), Expect = 5e-06
Identities = 147/621 (23%), Positives = 201/621 (32%), Gaps = 65/621 (10%)
Query: 324 FTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQ-PEEDKYSKPTAPAPSAPPS 382
F + + +S G PF PA + L + D + P ++ P+ + T+ +P P S
Sbjct: 526 FPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLS 585
Query: 383 PSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTG----SGAS 438
P A K+ L E + P ++ + A Y P G S
Sbjct: 586 PEATLAKKS-LGEPLPIGK---PASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLI 641
Query: 439 AGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPG-RPKGSRNKEGTGGPAAPS 497
T P SA P T G AS PK KEGT P
Sbjct: 642 TPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTL-TTLPL 700
Query: 498 LPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPS--GSLPSLSLESPLLGAGIYTS 555
+P+A + A SP + L++ P S+PS SL P G T
Sbjct: 701 VPTA--SENCPVAPSP-------QNTCAPLATLVLAPEIPKSVPSPSL--PPAGTPPGTK 749
Query: 556 NKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSASISTTQVFSL 615
D ISH+ L V S+P P S + S T T + S S V
Sbjct: 750 KVDGISHTSA-LAPVASSPKEC----PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804
Query: 616 AGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQESLSSMSPISS 675
+ + TP+G ++ +S E+S P+ SLS S
Sbjct: 805 TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL---------------PENSLSFQGSKDS 849
Query: 676 LPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLKALHALQKENQR 735
T +P G P + L K+ + VN+ K A Q
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL-PFPKEGPATPAPKQA 908
Query: 736 LQEQILSLTAKKERLQILNVQLSV-PFPALPAALPAANGPVP--GPYGLPPQAGSSDSLS 792
+ S + KK R + P P PAA P P GP P+ + +
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 793 TSKSPPGKSSLGLDNSLSTS-SEDPHSGCPSRSSSSLSFHSTPPPLPLLQQSPATLPLAL 851
T SP G + T + P S P ++ S P P + SP P A
Sbjct: 969 TPPSPKGGPATPSPKGAPTPPAATPPS--PKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 852 P---GA---PAPLPPQPQNGLGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNG 905
P GA PA PP P+ P G P A L G P L G
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA--TLPSPKGGPATP------SLKG 1078
Query: 906 AAAPNPASLSQAGGAPTLQLP 926
A P A+ G P P
Sbjct: 1079 APTPPAATPPSPKGGPATPSP 1099
Score = 38.9 bits (89), Expect = 0.027
Identities = 196/896 (21%), Positives = 294/896 (32%), Gaps = 172/896 (19%)
Query: 257 ESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLS 316
++ PS L+ P V T SS +S + S S E ++ + S
Sbjct: 325 QTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAP----S 380
Query: 317 SGKGVSSFTSASSSSSSSSS-SSGGPFQPAVSS-LQSSPDFSA-FPKLEQPEEDKYSKPT 373
KG S+ +S + S S S + ++ P S L+SSP+ + +P + Q S T
Sbjct: 381 VDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVS--SVGT 438
Query: 374 APAPSAPPSPSAPEPPKADLFEQKVVFS---GFGPIMRFSTTTSSSGRARAPSPGDYKSP 430
P P A P FE S GPI T+ + A +P K P
Sbjct: 439 TPLVVTNPCTIAAAPTTT--FEVATCVSPPMSSGPISNIEPTSPA---ALVMAPVAPKEP 493
Query: 431 HVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGT 490
T R+P P P D K K + P +G+
Sbjct: 494 -----STQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQ 548
Query: 491 GGPAAPS----LPSAQLA-----GFTATAASPFSGGSLVSSGLGGLSSRTFG---PSGSL 538
G LP Q A F +T++SP + S L+ ++ G P G
Sbjct: 549 AGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSP----EIPLSPEATLAKKSLGEPLPIGK- 603
Query: 539 PSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSP--F 596
P+ S+ SPL G S S++G + PL S L P +A P S P
Sbjct: 604 PASSMTSPL-GVNSSASVIKTDSYAG----PDSAGPLLKSSLITPTVAAFPLESADPAGV 658
Query: 597 TSTLPSSSASISTTQVFSLAGSTFSLPSTH---------------------IFGTPMGAV 635
T +++ +TT L G+ P H + +P
Sbjct: 659 APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTC 718
Query: 636 NPLLSQAESSHTEPDLEDCSFRCRGTSP-QESLSSMSPISSLPALFDQTASAPCGGGQLD 694
PL + + + S GT P + + +S S+L + AS+P D
Sbjct: 719 APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPV----ASSPKECPTED 774
Query: 695 PAAPGTTNMEQLLEKQGDGEA--GVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQI 752
A T + + L D + GV++ K +K + I +L++ ++
Sbjct: 775 SGASATASSKGTLTYLADSPSPLGVSVSPQTKR-PPTKKGSAGPDTPIGNLSSPVSPVEA 833
Query: 753 LNV-QLSVPFPALPAALPAANGPVP-GPYGLP-PQAGSSDSLSTSKSPPGKSSLGLDNSL 809
+ + S+ F + + P P P G P P A + S PP ++ +L
Sbjct: 834 SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL 893
Query: 810 STSSEDPHSGCPSR-------SSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQP 862
E P + P + SSS +TP P + SP+ P P PA PP P
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI-PASPS--PKGAPTPPAATPPSP 950
Query: 863 QNG-------------LGRAPGAAGLGAMPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAP 909
+ G P G A P +G A + P G A P
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGG-------PATP 1003
Query: 910 NPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQ 969
+P GAPT P + + + SP TP
Sbjct: 1004 SPK------GAPT---PPAVTPPSPK-------------------GSPAATP-------- 1027
Query: 970 MIQQIQQKRELQRLQMAGGSQLPMASLLAGSSTPLLSAGTPGLLPTASAPPLLPAGALVA 1029
P + ++TP G+P P P PA L +
Sbjct: 1028 ---------------------FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Query: 1030 PSLGNNTSLMAAA---AAAAAVAAAGGPPVLTAQTNPFLSLSGAEGSGGGPKGGTA 1082
P G T + A AA + GGP A +P + + PKGG A
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGP----ATPSPKGAPMPPAATPPSPKGGLA 1118
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 63.5 bits (153), Expect = 1e-09
Identities = 142/644 (22%), Positives = 230/644 (35%), Gaps = 95/644 (14%)
Query: 257 ESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHS--LSHKGKK 314
ES S P T S SA+S E T + +S E+ S+ + LS K
Sbjct: 144 ESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTT 203
Query: 315 LSSGKGVSSFT---SASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSK 371
S T + ++SS S S+ +P + + PD + P + Q +S
Sbjct: 204 FYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSI 263
Query: 372 PTAPAPSAPPSPSAPEP--PKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSP--GDY 427
P + + P + P P++ F G+ R T++SG A +P
Sbjct: 264 PGSTDTTLSPGTTTPSSLGPESTTFHSS---PGYTKTTRLPDNTTTSGLLEASTPVHSST 320
Query: 428 KSPHVTGSGASAGTHKRMP-ALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRN 486
SPH T S AS+ TH+ P + P D +P P +
Sbjct: 321 GSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSP-----------------APSGTTSAFV 363
Query: 487 KEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLSLESP 546
K T ++PS ++P + S S+ LG T S + + + P
Sbjct: 364 KLSTTYHSSPS-------------STPTTHFSASSTTLGHSEESTPVHSSPVATATTPPP 410
Query: 547 LLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALPRLSRSPFTSTLPSSSAS 606
A + H P SS+ G SA S + S+ PS++A+
Sbjct: 411 ARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAA 470
Query: 607 ISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSHTEPDLEDCSFRCRGTSPQES 666
++ T S GST +TH ++ ++++SH+ PD + G++P
Sbjct: 471 LAHTSYHSSLGST---ETTHF--RDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVL 525
Query: 667 L--SSMSPISSLPALFDQTASAPCGGGQLDPAAPGTTNMEQLLEKQGDGEAGVNIVEMLK 724
+ S+ SPISS G A PG+T L EK + +
Sbjct: 526 VGDSTPSPISS--------------GSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTH 571
Query: 725 ALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPAALPAA-NGPVPGPYGLPP 783
++ + E+ + ++ S P L A+ + P P L P
Sbjct: 572 LPASMTSSG--VSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSP 629
Query: 784 QAGSSDSL----STSKSPPGKSSLGL--DNS-----------LSTSSEDPH-----SGCP 821
+ ++ SL +T S PG + L DN+ + +S+ PH +G
Sbjct: 630 GSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGST 689
Query: 822 SRSSSSLSFHSTPP-----PLPLLQQSPATLPLALP-GAPAPLP 859
+R S +FHS P P P S P G+P+ +P
Sbjct: 690 TRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIP 733
Score = 54.3 bits (129), Expect = 6e-07
Identities = 117/495 (23%), Positives = 183/495 (36%), Gaps = 74/495 (14%)
Query: 256 PESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKL 315
P SP + L+P T+ VS +++S ST T+ + S + SH
Sbjct: 1005 PRSPDTTLSPAST-TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS 1063
Query: 316 SSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAP 375
+ T+ASS S++ GP + L PD + L + +S +P
Sbjct: 1064 TDTTLSPRSTTASSLGPESTTFHSGPGSTETTLL---PDNTTASGLLEASTPVHSSTGSP 1120
Query: 376 APSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTT------TSSSGRARAPSPGDYKS 429
+ P+ S ++ F+ P +T+ T+S G SP +
Sbjct: 1121 RTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHG-----SPSSIPT 1175
Query: 430 PHVTGSGASAGTHKRMPALSATPVPADETPE------TGLKEKK-----HKASKRSRHGP 478
H + S + G + + ++PV TP +GL E+ S ++ H P
Sbjct: 1176 THFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFP 1235
Query: 479 ------GRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLV------SSGLGG 526
GR + SR + S PS A + S GS+ SS G
Sbjct: 1236 ESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSG 1295
Query: 527 LSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTS 586
S + S S P + +PL A TS + S + + T L+S T+
Sbjct: 1296 RSEESTA-SHSSPDTNGITPL-PAHFTTSGRIAESTTFYISPGSMETTLAS-------TA 1346
Query: 587 ALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQAESSH 646
P LS ++ L SSS S T S S+ S+ I G P L SQAES+H
Sbjct: 1347 TTPGLSAK--STILYSSSRSPDQTL------SPASMTSSSISGEPTS----LYSQAESTH 1394
Query: 647 TEP----------DLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTASAPCG--GGQLD 694
T E +F + P + +++SP S + F Q + P G L
Sbjct: 1395 TTAFPASTTTSGLSQESTTFH---SKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALS 1451
Query: 695 PAAPGTTNMEQLLEK 709
+P +T + L E+
Sbjct: 1452 TVSPASTTVPGLSEE 1466
Score = 52.8 bits (125), Expect = 2e-06
Identities = 155/701 (22%), Positives = 242/701 (34%), Gaps = 138/701 (19%)
Query: 275 SSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHK----GKKLSSGKGVSSFTSASSS 330
SS S+ + H + S S ESK SS +++ G S G S+ + SS
Sbjct: 478 SSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSG 537
Query: 331 SSSSSSSSGGPFQPAVS-------SLQSSPDFSAFPK------LEQPEEDKYSKPTAPAP 377
S +++ G +P +S S SPD + P + + +S+P +
Sbjct: 538 SMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHT 597
Query: 378 SAPP--------------SPSAPEPPKADLFEQKVVFSGFGP---------------IMR 408
+A P S S+P P L S GP ++
Sbjct: 598 TAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLP 657
Query: 409 FSTTTSSSGRARAPSPGDYKSPHVTGSGASAGT--------HKRMPALSATPVPADET-- 458
+TT S A P +SPH T S A + T H + P P T
Sbjct: 658 DNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSA 717
Query: 459 ---PET---------------------GLKEK-----KHKASKRSRHGPGRPKGS-RNKE 488
P T GL E+ S ++ H P S R +E
Sbjct: 718 FVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 777
Query: 489 GTGG--------PAAPSLPSAQLAGFTATAASPFSGGSL---VSSGLGGLSSRTFGPSGS 537
T +APS SA + T+ +SP S + SS G S + S
Sbjct: 778 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSS 837
Query: 538 --------LPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSALP 589
LP+ S S LLG S PIS SG M +T L S P +
Sbjct: 838 QDATGTIVLPARSTNSVLLG----ESTTSPIS-SGSME----TTALPGSTTTPGLSERST 888
Query: 590 RLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLP-STHIFGTPMGAVNPLLSQ-AESSHT 647
SP + S AS +++ V + ++ S P STH P P LS+ + +SH+
Sbjct: 889 TFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 948
Query: 648 EPDLEDCSFRCRGTSPQESLSSMSPISSLPALFDQTASAPCGGGQLDPAA-PGTTNMEQL 706
P D +++ P S+ L + ++P G + A PG+T L
Sbjct: 949 SPGSTD--------------TTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGL 994
Query: 707 LEKQGDGEAGVNIVEMLKALHALQKENQRLQEQILSLTAKKERLQILNVQLSVPFPALPA 766
EK + + L + + E+ + ++ S P +
Sbjct: 995 SEKSTTFYSSPRSPD--TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQ 1052
Query: 767 ALPAA-NGPVPGPYGLPPQAGSSDSL----STSKSPPGKSSLGLDNSLSTSSEDPHSGCP 821
A+ + P L P++ ++ SL +T S PG + L +T+S + P
Sbjct: 1053 ESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTP 1112
Query: 822 SRSSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQP 862
SS+ + P +Q +T + P + +P P
Sbjct: 1113 VHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPP 1153
Score = 50.4 bits (119), Expect = 9e-06
Identities = 99/460 (21%), Positives = 152/460 (33%), Gaps = 69/460 (15%)
Query: 210 SGFISGRRSRSASPSTQQEKH----PTHHERGQKKSRKDKERLKQKHKKRPESPPSILTP 265
SG + + +SP + Q H T RG++ + S PS +
Sbjct: 744 SGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTI-----SSAPSTTSA 798
Query: 266 PVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFT 325
V SS S+++ H + TS S ES SS + G
Sbjct: 799 LVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDAT-----------GTIVLP 847
Query: 326 SASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPP---- 381
+ S++S S+ P + P + P L + +S P +PA + P
Sbjct: 848 ARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 907
Query: 382 ----------SPSAPEPPKADLFEQKVVFSGFG---------------PIMRFSTTTSSS 416
S S P F G ++ STTT
Sbjct: 908 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLV 967
Query: 417 GRARAP--SPGDYKSPHVTGSGASAGTHKRMPALSATPVPAD------ETPETGLKEKKH 468
G S G ++ + GS +AG ++ ++P D T +G+ E+
Sbjct: 968 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE-- 1025
Query: 469 KASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLS 528
+ SR G G + S S G T T SP S +S LG S
Sbjct: 1026 STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP---RSTTASSLGPES 1082
Query: 529 SRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGPPGTSAL 588
+ GS + L +G+ ++ P+ S G R S S++ G T
Sbjct: 1083 TTFHSGPGSTETTLLPDNTTASGLLEAS-TPVHSSTGSPRTTLSPAGSTTRQGESTTFQS 1141
Query: 589 PRLSRS--PFTSTLPSSSASISTTQVFSLAGSTFSLPSTH 626
S+ P T S+ +STT GS S+P+TH
Sbjct: 1142 WPSSKDTMPAPPTTTSAFVELSTTS----HGSPSSIPTTH 1177
Score = 44.3 bits (103), Expect = 6e-04
Identities = 109/487 (22%), Positives = 169/487 (34%), Gaps = 74/487 (15%)
Query: 259 PPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGK---KSSSHSLSHKGKKL 315
P S T P PT S++SH S+ T+ S S + S+ S G
Sbjct: 702 PSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQ 761
Query: 316 SSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAP 375
+ S TS S++S SS ++ S+P S L + +S P +
Sbjct: 762 TMHFPESDTTSGRGEESTTSHSS------TTHTISSAP--STTSALVEEPTSYHSSPGST 813
Query: 376 APSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSS----SGRARAPSPGDYKSPH 431
A + P S + G I+ + +T+S S G ++
Sbjct: 814 ATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTA 873
Query: 432 VTGSGASAGTHKR------MPALSATPVPADETPETGLKEKKHKASKR-----------S 474
+ GS + G +R P AT + T +G+ E+ + R S
Sbjct: 874 LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS 933
Query: 475 RHGPGRPKGSRNKEGTGGPA----APSLPSAQLAGFTATAASPFSGGSLVSSGLGGLS-- 528
PG + S + G P+ + L G T SP S GS ++ L G +
Sbjct: 934 TTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTT--SPISSGSTETTALPGSTTT 991
Query: 529 ------SRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAVCSTPLSSSLLGP 582
S TF S P +L SP S + SH S P S+
Sbjct: 992 AGLSEKSTTFYSSPRSPDTTL-SPASTTSSGVSEESTTSH---------SRPGSTHTTAF 1041
Query: 583 PGTSALPRLSRSPFTSTLPSSSASISTTQVFSLAGSTFSLPSTHIFGTPMGAVNPLLSQA 642
PG++ +P +S+ T++ S ++ +T S S+ ST P LL
Sbjct: 1042 PGSTTMPGVSQES-TASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTETTLL--- 1097
Query: 643 ESSHTEPDLEDCSFRCRGTSPQES-----LSSMSPISSLPALFDQTA--SAPCGGGQLDP 695
PD S ++P S +++SP S + T S P + P
Sbjct: 1098 ------PDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTM-P 1150
Query: 696 AAPGTTN 702
A P TT+
Sbjct: 1151 APPTTTS 1157
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 62.4 bits (150), Expect = 2e-09
Identities = 96/385 (24%), Positives = 137/385 (35%), Gaps = 41/385 (10%)
Query: 175 GYCKYHFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQ------- 227
G+ ++ S ++S +S G G G G G G G R RS+S S+
Sbjct: 230 GFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSG 289
Query: 228 EKHPTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEAS 287
+ H R SR+ ++ S SS + S H+E+
Sbjct: 290 SRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHG--------QHGSGSSYSYSRGHYESG 341
Query: 288 TQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVS 347
+ +TS + G SS H SG G SS S+S +SSSG Q S
Sbjct: 342 SGQTSGFGQHESGSGQSSGYSKH-----GSGSGHSSSQGQHGSTSGQASSSG---QHGSS 393
Query: 348 SLQSS---PDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFG 404
S QSS SA + +P S S P S G
Sbjct: 394 SRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSG 453
Query: 405 PIMRFSTTTSSSGRARAPSPGDYKS---PHVTGSGASA--GTHKRMPALSATPVPADETP 459
P + S + SSG S ++ S H +GSG S+ G H S+ +
Sbjct: 454 PYV--SGSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSA 511
Query: 460 ETGLKEKKHKASKR-----SRHGPG---RPKGSRNKEGTGGPAAPSLPSAQLAGFTATAA 511
+ +H + R SRHG G P SR + +G + S +++
Sbjct: 512 GSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSR 571
Query: 512 SPFSGGSLVSSGLGGLSSRTFGPSG 536
P+ GS SSGLG SR+ SG
Sbjct: 572 GPYESGSGHSSGLGHQESRSGQSSG 596
Score = 51.2 bits (121), Expect = 5e-06
Identities = 91/395 (23%), Positives = 134/395 (33%), Gaps = 55/395 (13%)
Query: 188 RHSSGGGGGGAGGGGGSMGGGGSGF-------ISGRRSRSASPSTQQEKHPTHHERGQKK 240
+H SG G + G GS+ G SGF S S+ S S+ + H R +
Sbjct: 677 QHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQS 736
Query: 241 SRKDK------------ERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSH--HEA 286
SR ++ + H+ + SSS SSSH H +
Sbjct: 737 SRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGS 796
Query: 287 STQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASS--SSSSSSSSSGGPFQP 344
T +S G +S H+ SG+G S SAS SS S+ G
Sbjct: 797 GTSCSSSCGHYESGSGQASGFGQHES---GSGQGYSQHGSASGHFSSQGRHGSTSGQSSS 853
Query: 345 AVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFG 404
+ SS S++ + E A S S P +G
Sbjct: 854 SGQHDSSSGQSSSYGQHESASHH------ASGRGRHGSGSGQSPGHGQRGSGSGQSPSYG 907
Query: 405 PIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAG--THKRMPALSATPVPADETPETG 462
S +SSSGR + S H + SG S+G H S++
Sbjct: 908 RHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQS 967
Query: 463 LKEKKHKASKRS-----RHGPG----------------RPKGSRNKEGTGGPAAPSLPSA 501
+ ++H +S S +HG G P SR + G+G + S
Sbjct: 968 SRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPY 1027
Query: 502 QLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSG 536
+ +++ P+ GS SSGLG SR+ SG
Sbjct: 1028 RSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 1062
Score = 48.9 bits (115), Expect = 3e-05
Identities = 99/398 (24%), Positives = 136/398 (34%), Gaps = 57/398 (14%)
Query: 188 RHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG--QKKSRKDK 245
RH SG G + G GS G SGF S S S Q + H G Q SR +
Sbjct: 1613 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 1672
Query: 246 ERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGK---K 302
++H S S S SS H + SR G
Sbjct: 1673 SSRGERHGSSSRSSSRY--------GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGH 1724
Query: 303 SSSHSLSHKGKKLSSGKGV--------SSFTSASSSSSSSSS-----SSGGPF----QPA 345
SSSH G SS +G S F S S SS+ S G F Q
Sbjct: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1784
Query: 346 VSSLQSSP-DFSAFPKLEQPEEDKYSKPTAPAPS--APPSPSAPEPPKADLFEQKVVFSG 402
+S QSS D + ++ ++ + S S S P + S
Sbjct: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSS 1844
Query: 403 FGPIMRFSTTTSSSGRARAPSP-----GDYKSP---------HVTGSGASAG--THKRMP 446
+G S +SSSGR + S G ++S H +GSG S+ H
Sbjct: 1845 YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRS 1904
Query: 447 ALSATPVPADETPETGLKEKKHKASKRS-----RHGPGR---PKGSRNKEGTGGPAAPSL 498
S+ + + +H + R +HG G P SR + G+G + S
Sbjct: 1905 GQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1964
Query: 499 PSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSG 536
+++ P+ GS SSGLG SR+ SG
Sbjct: 1965 GPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSG 2002
Score = 48.5 bits (114), Expect = 3e-05
Identities = 88/386 (22%), Positives = 131/386 (33%), Gaps = 43/386 (11%)
Query: 175 GYCKYHFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHH 234
G+ + S ++S +S G G G G G G G R S+S S+ H H
Sbjct: 1166 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS---HYGQH 1222
Query: 235 ERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSES 294
G ++S H ++ S +P + S+S H S + +S
Sbjct: 1223 GSGSRQS--------SGHGRQGSG--SGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 1272
Query: 295 SRESKGKKSSSHSLSHKGKKLSS-----GKGVSSFTSASSSSSSSSSSSGGPFQPAVSSL 349
ES+ SS G SS G G F S S+S SS F SS
Sbjct: 1273 PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS--TFDQEGSST 1330
Query: 350 QSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRF 409
S + + Y + A + SPS G G
Sbjct: 1331 GQSSSYGHRGS-GSSQSSGYGRHGA---GSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1386
Query: 410 STTTSSSGRARAPSPGDYKSP---------HVTGSGASAG--THKRMPALSATPVPADET 458
S+ SG ++ G ++S H +GSG S+ H S+ +
Sbjct: 1387 SSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSS 1446
Query: 459 PETGLKEKKHKASKRS-----RHGPGR---PKGSRNKEGTGGPAAPSLPSAQLAGFTATA 510
+ +H + R +HG G P SR + G+G + S +++
Sbjct: 1447 SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS 1506
Query: 511 ASPFSGGSLVSSGLGGLSSRTFGPSG 536
P+ GS SSGLG SR+ SG
Sbjct: 1507 RGPYESGSSHSSGLGHRESRSGQSSG 1532
Score = 46.6 bits (109), Expect = 1e-04
Identities = 86/386 (22%), Positives = 132/386 (34%), Gaps = 43/386 (11%)
Query: 175 GYCKYHFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHH 234
G+ + S ++S +S G G G G G G S R R S S ++ H
Sbjct: 2106 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ--SSRGERHGSSSGSSSRYGQHG 2163
Query: 235 ERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSES 294
++ S ++ H P+ + S + SS H + S
Sbjct: 2164 SGSRQSSGHGRQGSGSGHS---------------PSRGRHGSGSGHSSSHGQHGSGSGRS 2208
Query: 295 SRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPD 354
S + S HS S G+ SG G SS S S S S G + S +
Sbjct: 2209 SSRGPYESRSGHS-SVFGQH-ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 2266
Query: 355 FSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTS 414
S+ + + + + S S P + S +G S +S
Sbjct: 2267 GSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 2326
Query: 415 SSGRARAPSP-----GDYKSP---------HVTGSGASAG--THKRMPALSATPVPADET 458
SSGR + S G ++S H +GSG S+ H S+ +
Sbjct: 2327 SSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSS 2386
Query: 459 PETGLKEKKHKASKRS-----RHGPGR---PKGSRNKEGTGGPAAPSLPSAQLAGFTATA 510
+ +H + R +HG G P SR + G+G + S +++
Sbjct: 2387 SGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS 2446
Query: 511 ASPFSGGSLVSSGLGGLSSRTFGPSG 536
P+ GS SSGLG SR+ SG
Sbjct: 2447 RGPYESGSGHSSGLGHRESRSGQSSG 2472
Score = 44.3 bits (103), Expect = 6e-04
Identities = 102/425 (24%), Positives = 143/425 (33%), Gaps = 47/425 (11%)
Query: 175 GYCKYHFSKMKTSRHSSGGGGGGAGGG-GGSMGGGGSGFISGRRSRSASPSTQQEKHPTH 233
G+ H TS SS G GA G S G GSG S + S + + P H
Sbjct: 1071 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG--SSQSSGYGRQGSGSGQSPGH 1128
Query: 234 HERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSE 293
+RG + P S +SSS H + E+S
Sbjct: 1129 GQRGSGSRQS----------------------PSYGRHGSGSGRSSSSGQHGSGLGESSG 1166
Query: 294 -SSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSS----SSSSSSSSGGPFQPAVSS 348
ES +SSS+S G SSG G S SS SSS SS Q S
Sbjct: 1167 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS 1226
Query: 349 LQSS-PDFSAFPKLEQPEEDKYSKPTAPAPS-APPSPSAPEPPKADLFEQKVVFSGFGPI 406
QSS P ++ + S + +E + SG +
Sbjct: 1227 RQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR---SGHSSV 1283
Query: 407 MRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLK-E 465
F S SG + A S S H G T + ++ G +
Sbjct: 1284 --FGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGS 1341
Query: 466 KKHKASKRSRHGPGRPKG-SRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGL 524
++S RHG G + SR + G+G + S ++++ GS SSG
Sbjct: 1342 GSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF 1401
Query: 525 GGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAV--CSTPLSSSLLGP 582
G S ++ SG S G+G +S + S SG R S+ SSS G
Sbjct: 1402 GHHESSSWQSSGCTQHGS------GSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 1455
Query: 583 PGTSA 587
G+ +
Sbjct: 1456 HGSGS 1460
Score = 43.5 bits (101), Expect = 0.001
Identities = 83/360 (23%), Positives = 128/360 (35%), Gaps = 40/360 (11%)
Query: 187 SRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTH-------HERGQK 239
S+H SG G + G GS G S F + S + Q H H GQ+
Sbjct: 1768 SQHGSGSGHFCSQGQHGSTSGQSSTF-----DQEGSSTGQSSSHGQHGSGSSQSSSYGQQ 1822
Query: 240 KSRKDKERLKQKHKKRPESPPSI----LTPPVVPTADKVSSSASSSS---HHEASTQETS 292
S + + +H S ++ + S + SS HHE+S+ ++S
Sbjct: 1823 GSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS 1882
Query: 293 ESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSS 352
++ G S HS S+ ++ S G SS SSS SSSS G + SL
Sbjct: 1883 GYTQHGSG---SGHSSSY--EQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHG 1937
Query: 353 PDFSAFPKLEQPEEDKYSKPTAPAPSAPP--SPSAPEPPKADLFEQKVVFSGFGPIMRFS 410
S + P ++ + + S P S S + SG G R S
Sbjct: 1938 QHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLG--HRES 1995
Query: 411 TTTSSSGRARAPSPGDYKSPH-----VTGSGASAGTHKRMPALSATPVPADETPETGLKE 465
+ SSG + S + S H +G +S G H A+ + + G
Sbjct: 1996 RSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQH------GASSGQSSSHGQHGSGS 2049
Query: 466 KKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLG 525
+ R G G+ G + G+G +PS ++++ G SSG G
Sbjct: 2050 SQSSGYGRQGSGSGQSPG-HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFG 2108
Score = 42.0 bits (97), Expect = 0.003
Identities = 100/432 (23%), Positives = 148/432 (34%), Gaps = 78/432 (18%)
Query: 174 CGYCKYHFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTH 233
CG ++ S ++S H G G G G G G SG+ + + P++
Sbjct: 2029 CG--QHGASSGQSSSHGQHGSGSSQSSGYGRQGSG-----SGQSPGHGQRGSGSRQSPSY 2081
Query: 234 HERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSE 293
G R + P + +S HHE+S+ ++S
Sbjct: 2082 GRHGSGSGRSSSS---------GQHGPGL-------------GESSGFGHHESSSGQSSS 2119
Query: 294 SSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSS------SSSSSSSGGPFQPAVS 347
S+ G SS H + S +G +S+ SSS S S SSG Q + S
Sbjct: 2120 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGS 2179
Query: 348 SLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIM 407
S ++ + + S P S SG +
Sbjct: 2180 GHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESR---------------SGHSSV- 2223
Query: 408 RFSTTTSSSGRARAPSPGDYKSPHVTGSG--ASAGTHKRMPALSATPVPADETPETGLKE 465
F S SG + A S H +GSG S G H S+T E TG
Sbjct: 2224 -FGQHESGSGHSSA------YSQHGSGSGHFCSQGQHGSTSGQSST--FDQEGSSTG--- 2271
Query: 466 KKHKASKRSRHGPGRPKGSR-NKEGTGGPAAPSL-PSAQLAGFTATAASPFSGGSLVSS- 522
++S +HG G + S ++G+G +PS +G +++ SG SS
Sbjct: 2272 ---QSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 2328
Query: 523 ---GLGGLSSRTFG--PSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAV--CSTPL 575
G G S FG S S S G+G +S + S SG R S+
Sbjct: 2329 GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSG 2388
Query: 576 SSSLLGPPGTSA 587
SSS G G+ +
Sbjct: 2389 SSSSYGQHGSGS 2400
Score = 41.2 bits (95), Expect = 0.005
Identities = 74/353 (20%), Positives = 116/353 (32%), Gaps = 24/353 (6%)
Query: 187 SRHSSGGGGGGAGGGGGSMGG--GGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKD 244
S HSSG G G+ G S G G S S + S S Q H H +
Sbjct: 485 SGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPS 544
Query: 245 KERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSS 304
+ R + ++ P + S + SS + +SS + SS
Sbjct: 545 RGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSS 604
Query: 305 SHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQP 364
HS +H +SG+ S ++S SSS G + SS S + P
Sbjct: 605 GHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHG----SGSSQSSRYGQQGSGSGQSP 660
Query: 365 EEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSP 424
++ + S S ++ GP S +S G
Sbjct: 661 SRGRHGSDFGHSSSYGQHGSGSGWSSSN-----------GPHGSVSGQSSGFGHKSGSGQ 709
Query: 425 GDYKSPHVTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGS 484
S H +GS S+G K + +GL +S +HG G + S
Sbjct: 710 SSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGL------SSSYGQHGSGSHQSS 763
Query: 485 -RNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLGGLSSRTFGPSG 536
++G+G +PS + +++ G+ SS G S + SG
Sbjct: 764 GHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASG 816
Score = 41.2 bits (95), Expect = 0.005
Identities = 81/346 (23%), Positives = 121/346 (34%), Gaps = 58/346 (16%)
Query: 187 SRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKDKE 246
S H+SG G G+G G S G G G SG+ SPS +H + R R
Sbjct: 874 SHHASGRGRHGSGSGQ-SPGHGQRGSGSGQ-----SPS--YGRHGSGSGRSSSSGRHGS- 924
Query: 247 RLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSH 306
S SS H++S+ ++S ++ G S H
Sbjct: 925 ----------------------------GSGQSSGFGHKSSSGQSSGYTQHGSG---SGH 953
Query: 307 SLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEE 366
S S+ ++ S G SS + SSS SSSS G + SL S + P
Sbjct: 954 SSSY--EQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSR 1011
Query: 367 DKYSKPTAPAPSAPP--SPSAPEPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSP 424
++ + + S P S S + SG G R S + SSG + S
Sbjct: 1012 GRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLG--HRESRSGQSSGYGQHGSS 1069
Query: 425 GDYKSPH-----VTGSGASAGTHKRMPALSATPVPADETPETGLKEKKHKASKRSRHGPG 479
+ S H +G +S G H A+ + + G + R G G
Sbjct: 1070 SGHSSTHGQHGSTSGQSSSCGQH------GASSGQSSSHGQHGSGSSQSSGYGRQGSGSG 1123
Query: 480 RPKGSRNKEGTGGPAAPSLPSAQLAGFTATAASPFSGGSLVSSGLG 525
+ G + G+G +PS ++++ G SSG G
Sbjct: 1124 QSPG-HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFG 1168
Score = 40.4 bits (93), Expect = 0.009
Identities = 46/164 (28%), Positives = 60/164 (36%), Gaps = 39/164 (23%)
Query: 188 RHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG--QKKSRKDK 245
RH SG G + G GS G SGF S S S Q + H G Q SR +
Sbjct: 2553 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 2612
Query: 246 ERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSS 305
++H SS+ SSSH+ S ++SS
Sbjct: 2613 SSRGERH----------------------GSSSGSSSHY---------GQHGSGSRQSSG 2641
Query: 306 HSL--SHKGKKLSSGKGVSSFTSASS----SSSSSSSSSGGPFQ 343
H S G+ S G+ S +SS S S SSS GP++
Sbjct: 2642 HGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE 2685
Score = 39.7 bits (91), Expect = 0.016
Identities = 103/432 (23%), Positives = 147/432 (34%), Gaps = 78/432 (18%)
Query: 174 CGYCKYHFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTH 233
CG ++ S ++S H G G G G G GSG G R S S Q + H
Sbjct: 1559 CG--QHGASSGQSSSHGQHGSGSSQSSGYGRQ-GSGSGQSPGHGQR-GSGSRQSPSYGRH 1614
Query: 234 HERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSE 293
+ S + +S HHE+S+ ++S
Sbjct: 1615 GSGSGRSSSSGQH-------------------------GSGLGESSGFGHHESSSGQSSS 1649
Query: 294 SSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSS------SSSSSSSGGPFQPAVS 347
S+ G SS H + S +G +S+ SSS S S SSG Q + S
Sbjct: 1650 YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGS 1709
Query: 348 SLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGPIM 407
S ++ + + S P S SG +
Sbjct: 1710 GQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESR---------------SGHSSV- 1753
Query: 408 RFSTTTSSSGRARAPSPGDYKSPHVTGSG--ASAGTHKRMPALSATPVPADETPETGLKE 465
F S SG + A S H +GSG S G H S+T E TG
Sbjct: 1754 -FGQHESGSGHSSA------YSQHGSGSGHFCSQGQHGSTSGQSST--FDQEGSSTG--- 1801
Query: 466 KKHKASKRSRHGPGRPKGSR-NKEGTGGPAAPSL-PSAQLAGFTATAASPFSGGSLVSS- 522
++S +HG G + S ++G+G +PS +G +++ SG SS
Sbjct: 1802 ---QSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSS 1858
Query: 523 ---GLGGLSSRTFG--PSGSLPSLSLESPLLGAGIYTSNKDPISHSGGMLRAV--CSTPL 575
G G S FG S S S G+G +S + S SG R S+
Sbjct: 1859 GRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSG 1918
Query: 576 SSSLLGPPGTSA 587
SSS G G+ +
Sbjct: 1919 SSSSYGQHGSGS 1930
Score = 39.3 bits (90), Expect = 0.021
Identities = 107/433 (24%), Positives = 142/433 (32%), Gaps = 77/433 (17%)
Query: 188 RHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG--QKKSRKDK 245
+H SG G + G GS G SGF S S Q + H Q SR +
Sbjct: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQ 1436
Query: 246 ERLKQKHKKRPESPPSI----------LTPPVVPTADKVSSSASSSSHHEASTQETSESS 295
++H S S L + S S S H S Q +S S
Sbjct: 1437 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSP 1496
Query: 296 RESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSS------SSSSSSSSGGPF------- 342
S SSS G SSG G S SS SSS SS+ G
Sbjct: 1497 YGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1556
Query: 343 ----QPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAP------------PSPSAP 386
Q SS QSS Q Y + + + +P PS
Sbjct: 1557 SSCGQHGASSGQSSSHGQHGSGSSQ--SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1614
Query: 387 EPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASA--GTHKR 444
SG G F SSSG++ + S H +GSG S+ G H
Sbjct: 1615 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS------YSQHGSGSGHSSGYGQHGS 1668
Query: 445 MPALSATPVPADETPETGLKEKKHKASKRS-----RHGPG-RPKGSRNKEGTGGPAAPSL 498
S+ + ++H +S RS +HG G R ++G+G +PS
Sbjct: 1669 RSGQSS-------------RGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSR 1715
Query: 499 PSAQLAGFTATAASPFSGGSLVSSGLGGLSSRT-----FG--PSGSLPSLSLESPLLGAG 551
+++ GS SS G SR+ FG SGS S + G+G
Sbjct: 1716 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSG 1775
Query: 552 IYTSNKDPISHSG 564
+ S S SG
Sbjct: 1776 HFCSQGQHGSTSG 1788
Score = 39.3 bits (90), Expect = 0.021
Identities = 44/169 (26%), Positives = 60/169 (35%), Gaps = 14/169 (8%)
Query: 174 CGYCKYHFSKMKTSRHSSGGGGGGAGGGGGSMG-GGGSGFISGRRSRSASPSTQQEKHPT 232
CG ++ S ++S H G G G G G G G G+R + S +H +
Sbjct: 2499 CG--QHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS 2556
Query: 233 HHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETS 292
R + + ES + S S S H Q S
Sbjct: 2557 GSGRSSSSGQHGSGLGESSGFGHHESSSG--------QSSSYSQHGSGSGHSSGYGQHGS 2608
Query: 293 ESSRESKGKK--SSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSG 339
S + S+G++ SSS S SH G+ SG SS S S S S G
Sbjct: 2609 RSGQSSRGERHGSSSGSSSHYGQH-GSGSRQSSGHGRQGSGSGQSPSRG 2656
Score = 38.1 bits (87), Expect = 0.046
Identities = 53/184 (28%), Positives = 64/184 (34%), Gaps = 30/184 (16%)
Query: 175 GYCKYHFSKMKTSRHSSGGGGGGAGGG-GGSMGGGGSGFISGRRSRSASPSTQQEKHPTH 233
G+ H TS SS G GA G S G GSG S + S + + P H
Sbjct: 2481 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSG--SSQSSGYGRQGSGSGQSPGH 2538
Query: 234 HERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSE 293
+RG + P S +SSS H + E+S
Sbjct: 2539 GQRGSGSRQS----------------------PSYGRHGSGSGRSSSSGQHGSGLGESSG 2576
Query: 294 -SSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSS----SSSSSSSSGGPFQPAVSS 348
ES +SSS+S G SSG G S SS SSS SS Q S
Sbjct: 2577 FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS 2636
Query: 349 LQSS 352
QSS
Sbjct: 2637 RQSS 2640
Score = 37.0 bits (84), Expect = 0.10
Identities = 96/410 (23%), Positives = 130/410 (31%), Gaps = 43/410 (10%)
Query: 182 SKMKTSRHSSGGGGG--------GAGGGGGSMG---GGGSGFISGRRSRSASPSTQQEKH 230
S SR G G G G+G G S G GSG SG +S S Q +
Sbjct: 1826 SGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS-SWQSSGY 1884
Query: 231 PTHHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQE 290
H S ++ + R E S SS+S H S Q
Sbjct: 1885 TQHGSGSGHSSSYEQHGSRSGQSSRGEQHGS-----------SSGSSSSYGQHGSGSRQS 1933
Query: 291 TSESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSS-----SGGPFQPA 345
S +S S S G SG G SS S S SSS SG
Sbjct: 1934 LGHGQHGSGSGQSPSPSRGRHG----SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSG 1989
Query: 346 VSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEPPKADLFEQKVVFSGFGP 405
+ +S S+ S ++ S S + + G G
Sbjct: 1990 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGS 2049
Query: 406 IMRFSTTTSSSGRARAP-----SPGDYKSP----HVTGSGASAGTHKRMPALSATPVPAD 456
SG ++P G +SP H +GSG S+ + + P L +
Sbjct: 2050 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGH 2109
Query: 457 ETPETGLKEKKHKASKRSRHGPGRPK-GSRNKEGTGGPA-APSLPSAQLAGFTATAASPF 514
+G + S H G + GSR+ + + G S S+ G + +
Sbjct: 2110 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169
Query: 515 SGGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAGIYTSNKDPISHSG 564
SG SG G SR SGS S S G+G +S S SG
Sbjct: 2170 SGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
Score = 37.0 bits (84), Expect = 0.10
Identities = 103/420 (24%), Positives = 133/420 (31%), Gaps = 76/420 (18%)
Query: 188 RHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERG--QKKSRKDK 245
+H SG G + G GS G SGF S S Q + H Q SR +
Sbjct: 2317 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 2376
Query: 246 ERLKQKHKKRPESPPSI----------LTPPVVPTADKVSSSASSSSHHEASTQETSESS 295
++H S S L + S S S H S Q +S S
Sbjct: 2377 SSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSP 2436
Query: 296 RESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSS------SSSSSSSSGGPF------- 342
S SSS G SSG G S SS SSS SS+ G
Sbjct: 2437 YGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 2496
Query: 343 ----QPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAP------------PSPSAP 386
Q SS QSS Q Y + + + +P PS
Sbjct: 2497 SSCGQHGASSGQSSSHGQHGSGSSQ--SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2554
Query: 387 EPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMP 446
SG G F SSSG++ + S H +GSG S+G +
Sbjct: 2555 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSS------YSQHGSGSGHSSGYGQH-- 2606
Query: 447 ALSATPVPADETPETGLKEKKHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSAQLAGF 506
+ ++ E+ +S S H GSR G G + S
Sbjct: 2607 --------GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS--------- 2649
Query: 507 TATAASPFSGGSLVSSGLGGLSSRTFGPSGSLPSLS---LESPLLGAGIYTSNKDPISHS 563
SP G SGLG SS SGS S S ES L + ++ ++ HS
Sbjct: 2650 ---GQSPSRGRH--GSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704
Score = 35.0 bits (79), Expect = 0.39
Identities = 42/169 (24%), Positives = 60/169 (35%), Gaps = 18/169 (10%)
Query: 175 GYCKYHFSKMKTSRHSSGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHH 234
G+ + S ++S +S G G G G G G G R S+S S+ H H
Sbjct: 2576 GFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS---SHYGQH 2632
Query: 235 ERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSES 294
G ++S H + + S +P + S+S H S + +S
Sbjct: 2633 GSGSRQS--------SGHGR--QGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 2682
Query: 295 SRESKGKKSSSHSLSHKGKKLSS-----GKGVSSFTSASSSSSSSSSSS 338
ES+ SS G SS G G F S S+S SS
Sbjct: 2683 PYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS 2731
Score = 35.0 bits (79), Expect = 0.39
Identities = 48/169 (28%), Positives = 59/169 (34%), Gaps = 17/169 (10%)
Query: 187 SRHSSGGGGGGAGGG------------GGSMGGGGSGFISGRRSRSASPSTQQEKHPT-- 232
SR SSG G G+G G G S G G SGR S S P + H +
Sbjct: 2636 SRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS-SRGPYESRLGHSSVF 2694
Query: 233 -HHERGQKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQET 291
HE G S + + T T D+ SS SS + +
Sbjct: 2695 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGS-TSGQSSTFDQEGSSTGQSSSYGHRGSGS 2753
Query: 292 SESSRESKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGG 340
S+SS + S SLSH SG+ S S S SS S G
Sbjct: 2754 SQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHG 2802
Score = 32.3 bits (72), Expect = 2.5
Identities = 79/373 (21%), Positives = 129/373 (34%), Gaps = 29/373 (7%)
Query: 213 ISGRRSRSASPSTQQEKHPTHHERG--QKKSRKDKERLKQKHKKRPESPPSILTPPVVPT 270
+SG + R + Q+E+ T E Q+ S ++ + L P
Sbjct: 96 VSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESI 155
Query: 271 ADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSHKGKKLSSGKGVS----SFTS 326
+ ++S S H + + ++S ++ S SH S +G + SG G S S
Sbjct: 156 SRRLSFQRDFSGQHNSYSGQSSSYGEQN----SDSHQSSGRG-QCGSGSGQSPNYGQHGS 210
Query: 327 ASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAP 386
S SSS+ + G Q + S S + + +S S S
Sbjct: 211 GSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRG 270
Query: 387 EPPKADLFEQKVVFSGFGPIMRFSTTTSSSGRARAPSPGDYKSPHVTGSGASAGTHKRMP 446
E ++ + G R S G SP + +G +S G H
Sbjct: 271 ERHRSSSGSSS-SYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGS 329
Query: 447 ALSAT----PVPADETPETGLKEK-KHKASKRSRHGPGRPKGSRNKEGTGGPAAPSLPSA 501
+ S + + +T G E ++S S+HG G G + +G G + S+
Sbjct: 330 SYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSG--SGHSSSQGQHGSTSGQASSS 387
Query: 502 QLAGFTATAASPF----------SGGSLVSSGLGGLSSRTFGPSGSLPSLSLESPLLGAG 551
G ++ +S + SG SSG G SGS S S G G
Sbjct: 388 GQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFG 447
Query: 552 IYTSNKDPISHSG 564
+S+ +S SG
Sbjct: 448 RSSSSGPYVSGSG 460
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 62.0 bits (149), Expect = 3e-09
Identities = 55/199 (27%), Positives = 86/199 (43%), Gaps = 17/199 (8%)
Query: 191 SGGGGGGAGGGGGSMGGGGSGFISGRRSRSASPSTQQEKHPTHHERGQKKSRKDKERLKQ 250
+GGGGGG+GGGGG GGGG G + + E+ + H +S K R
Sbjct: 3506 TGGGGGGSGGGGGGGGGGGGG--GSYHCLACESALCGEEALSQH----LESALHKHRTIT 3559
Query: 251 KHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRESKGKKSSSHSLSH 310
+ + + PS+L +S++ S++H S S ++ S +S S
Sbjct: 3560 RAARNAKEHPSLLPHSACFPDPSTASTSQSAAHSNDSPPPPSAAAPSSASPHASRKSWPQ 3619
Query: 311 KGKKLSSGKGVSSFTSASSSSSSSSSSSGGPFQPAVSSLQSSPDFSAFPKLEQPEEDKYS 370
+ S+ K S +SSS+ +SSS S QP++ + D+S E+ + D
Sbjct: 3620 VVSRASAAKPPSFPPLSSSSTVTSSSCSTSGVQPSM----PTDDYS-----EESDTDLSQ 3670
Query: 371 KPTAPAP--SAPPSPSAPE 387
K PA P PS P+
Sbjct: 3671 KSDGPASPVEGPKDPSCPK 3689
Score = 39.3 bits (90), Expect = 0.021
Identities = 82/332 (24%), Positives = 118/332 (35%), Gaps = 76/332 (22%)
Query: 730 QKENQRLQE--QILSLTAKKER------LQILNVQLSVPF--------------PALPAA 767
Q+E R+++ ++L L A+++ LQ LN+ + P P+LP
Sbjct: 3078 QQELDRIKKANEVLGLAAQQQGMFDNTPLQALNLPTAYPALQGIPPVLLPGLNSPSLPGF 3137
Query: 768 LP---AANGPVPGPYGLPPQAGSSDSLSTSKSPPGKSSLGLDN---SLSTSSEDPHSGCP 821
P A P P GLP S L TS P SS L + + +T + P
Sbjct: 3138 TPSNTALTSPKPNLMGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQ 3197
Query: 822 SRSSSSLSFHSTPPPLPLLQQSPAT-LPL-------------------ALPGAPAPLP-P 860
+ PPP P Q P LPL A G PLP P
Sbjct: 3198 QQQQQQQPQVQQPPPPPAAQPPPTPQLPLQQQQQRKDKDSEKVKEKEKAHKGKGEPLPVP 3257
Query: 861 QPQNGLGRAPGAAGLGA-MPMAEGLLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGG 919
+ + G AA + A +P E + L L A +P +L +
Sbjct: 3258 KKEKGEAPTATAATISAPLPTMEYAVDPAQ----------LQALQAALTSDPTALLTSQF 3307
Query: 920 APTL----------QLPGCLNSLTEQQRHLLQQQEQQLQQLQQLLA--SP----QLTPEH 963
P Q+PG L S Q + ++ L Q L SP Q ++
Sbjct: 3308 LPYFVPGFSPYYAPQIPGALQSGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQY 3367
Query: 964 QTVVYQMIQQIQQKRELQRLQMAGGSQLPMAS 995
Q + + IQQ QQ++ Q+ Q Q P AS
Sbjct: 3368 QQSLQEAIQQQQQRQLQQQQQQKVQQQQPKAS 3399
Score = 35.0 bits (79), Expect = 0.39
Identities = 48/169 (28%), Positives = 71/169 (42%), Gaps = 31/169 (18%)
Query: 824 SSSSLSFHSTPPPLPLLQQSPATLPLALPGAPAPLPPQPQNGLGRAPGAAGLGAMPMAEG 883
+SSS+S S+ P P++ G+ P + G AP + L +P
Sbjct: 1641 NSSSISLSSSTPS-----------PVSTSGSNTFTTSNPSSA-GIAPSSNLLSQVPTE-- 1686
Query: 884 LLGGLAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRHLLQQQ 943
S G+P LG GA N AS S+ A +L + S +QQ QQQ
Sbjct: 1687 -------SVGMPP---LGNPIGA---NIASPSEPKEANRKKLADMIASRQQQQ----QQQ 1729
Query: 944 EQQLQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQLP 992
+QQ QQ QQ + L V + Q++QQ+ L + Q+ + LP
Sbjct: 1730 QQQQQQQQQQQQAQTLAQAQAQVQAHLQQELQQQAALIQSQLFNPTLLP 1778
Score = 33.9 bits (76), Expect = 0.86
Identities = 28/91 (30%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 936 QRHLLQQQEQQLQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQ---RLQMAGGSQLP 992
Q HL Q+ +QQ +Q L +P L P H + + + Q+QQ++ L + A P
Sbjct: 1753 QAHLQQELQQQAALIQSQLFNPTLLP-HFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNP 1811
Query: 993 MASLLAGSSTPLLSAGTPGLLPTASAPPLLP 1023
SL S L+ PGLL A +P
Sbjct: 1812 EVSLPVTSGALTLTGTGPGLLEDLKAQVQVP 1842
Score = 32.0 bits (71), Expect = 3.3
Identities = 32/162 (19%), Positives = 57/162 (35%), Gaps = 19/162 (11%)
Query: 238 QKKSRKDKERLKQKHKKRPESPPSILTPPVVPTADKVSSSASSSSHHEASTQETSESSRE 297
+K KD++ Q + +S ++ + PT+ S+ S ++ + + +S
Sbjct: 2348 KKLCYKDEDEEGQDDSQNEDSMDAMEI--LTPTSSSCSTPMPSQAYSAPAPSANNTASSA 2405
Query: 298 SKGKKSSSHSLSHKGKKLSSGKGVSSFTSASSSSSSSSSSSGG-----------PFQPAV 346
+ + L+ K +G A S+ + + G P Q
Sbjct: 2406 FLQLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQGQPKPELQQQEQPEQKTN 2465
Query: 347 SSLQSSPDFSAFPKLEQPEEDKYSKPTAPAPSAPPSPSAPEP 388
+ Q P + P L QP P AP P P S+P P
Sbjct: 2466 TPQQKLPQLVSLPSLPQPP------PQAPPPQCPLPQSSPSP 2501
Score = 30.4 bits (67), Expect = 9.6
Identities = 47/167 (28%), Positives = 64/167 (38%), Gaps = 37/167 (22%)
Query: 834 PPPLPLLQQSPATLPLALPGAPAPL------PPQPQNGLGRAPGAAGLGAMPMAEGLLGG 887
PPPLP PA+ P A+P + P+ P QP L + +MPM +
Sbjct: 2048 PPPLPAAPPQPASTP-AIPASAPPITSPTIAPAQPSVPLTQL-------SMPMELPIFSP 2099
Query: 888 LAGSGGLPLNGLLGGLNGAAAPNPASLSQAGGAPTLQLPGCLNSLTEQQRH--LLQQQEQ 945
L +PL L PA L G P LP L L + Q + LLQQQ +
Sbjct: 2100 LM-MQTMPLQTL-----------PAQLPPQLG-PVEPLPADLAQLYQHQLNPTLLQQQNK 2146
Query: 946 QLQQLQQLLASPQLTPEHQTVVYQMIQQIQQKRELQRLQMAGGSQLP 992
+ ++T + V+ Q E Q +MA S LP
Sbjct: 2147 R--------PRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLP 2185
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,122,232
Number of Sequences: 37866
Number of extensions: 3290478
Number of successful extensions: 58805
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 641
Number of HSP's successfully gapped in prelim test: 1942
Number of HSP's that attempted gapping in prelim test: 27145
Number of HSP's gapped (non-prelim): 21619
length of query: 1093
length of database: 18,247,518
effective HSP length: 113
effective length of query: 980
effective length of database: 13,968,660
effective search space: 13689286800
effective search space used: 13689286800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.