Search of human proteins with 56788366

Search of human proteins with 56788366

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56788366 phosphatidylinositol-binding clathrin assembly
protein isoform 1 [Homo sapiens]
         (652 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56788366 phosphatidylinositol-binding clathrin assembly prote...  1287   0.0  
gi|56788368 phosphatidylinositol-binding clathrin assembly prote...  1158   0.0  
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...   509   e-144
gi|91982772 mucin 17 [Homo sapiens]                                    48   2e-05
gi|116284392 mucin 2 precursor [Homo sapiens]                          41   0.003
gi|151301154 mucin 6, gastric [Homo sapiens]                           40   0.009
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             38   0.034
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     37   0.044
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    37   0.057
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    37   0.057
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    37   0.075
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    37   0.075
gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens]        37   0.075
gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens]        37   0.075
gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens]        37   0.075
gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens]         37   0.075
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso...    36   0.097
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    36   0.13 
gi|7661968 epsin 4 [Homo sapiens]                                      35   0.17 
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      35   0.17 
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]     35   0.17 
gi|239752529 PREDICTED: similar to mucin [Homo sapiens]                35   0.17 
gi|239753106 PREDICTED: similar to hCG1817845 [Homo sapiens]           35   0.22 
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         35   0.28 
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            34   0.37 
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        34   0.37 
gi|33188443 microfilament and actin filament cross-linker protei...    34   0.37 
gi|33188445 microfilament and actin filament cross-linker protei...    34   0.37 
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    34   0.37 
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    34   0.37 

>gi|56788366 phosphatidylinositol-binding clathrin assembly protein
           isoform 1 [Homo sapiens]
          Length = 652

 Score = 1287 bits (3331), Expect = 0.0
 Identities = 652/652 (100%), Positives = 652/652 (100%)

Query: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60
           MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA
Sbjct: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60

Query: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
           DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM
Sbjct: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120

Query: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180
           STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD
Sbjct: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180

Query: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240
           FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF
Sbjct: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240

Query: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300
           LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT
Sbjct: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300

Query: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360
           TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP
Sbjct: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360

Query: 361 VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGD 420
           VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGD
Sbjct: 361 VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGD 420

Query: 421 PFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPH 480
           PFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPH
Sbjct: 421 PFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPH 480

Query: 481 PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL 540
           PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL
Sbjct: 481 PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL 540

Query: 541 DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAY 600
           DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAY
Sbjct: 541 DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAY 600

Query: 601 PATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM 652
           PATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
Sbjct: 601 PATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM 652


>gi|56788368 phosphatidylinositol-binding clathrin assembly protein
           isoform 2 [Homo sapiens]
          Length = 610

 Score = 1158 bits (2996), Expect = 0.0
 Identities = 602/660 (91%), Positives = 602/660 (91%), Gaps = 58/660 (8%)

Query: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60
           MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA
Sbjct: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60

Query: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
           DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM
Sbjct: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120

Query: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180
           STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD
Sbjct: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180

Query: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240
           FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF
Sbjct: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240

Query: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300
           LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT
Sbjct: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300

Query: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360
           TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP
Sbjct: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360

Query: 361 VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGD 420
           VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWG 
Sbjct: 361 VSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWG- 419

Query: 421 PFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPH 480
                                                            GFTPSPVAQPH
Sbjct: 420 -------------------------------------------------GFTPSPVAQPH 430

Query: 481 PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL 540
           PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL
Sbjct: 431 PSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDL 490

Query: 541 DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATM------- 593
           DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATM       
Sbjct: 491 DSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMNGMHFPQ 550

Query: 594 -APPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM 652
            APPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
Sbjct: 551 YAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM 610


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score =  509 bits (1310), Expect = e-144
 Identities = 285/504 (56%), Positives = 348/504 (69%), Gaps = 67/504 (13%)

Query: 1   MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLA 60
           MSGQ+LTDRI AAQ+SVTGSAV++ VCKATTHE+MGPKKKHLDYLIQ TNE NVNIPQ+A
Sbjct: 1   MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMA 60

Query: 61  DSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDM 120
           D+LFER TNSSWVVVFK+L+TTHHLMV+GNERFIQYLASRNTLFNLSNFLDKSG  GYDM
Sbjct: 61  DTLFERATNSSWVVVFKALVTTHHLMVHGNERFIQYLASRNTLFNLSNFLDKSGSHGYDM 120

Query: 121 STFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLD 180
           STFIRRYSRYLNEKA SYRQ+AFDF +VK+GADGVMRTM  EKLLK++PI+Q Q+DALL+
Sbjct: 121 STFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLE 180

Query: 181 FNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKF 240
           F+V+ NELTNGVINAAFMLLFKD I+LFA YN+G+INLLEK+F+MKK QCK+ L+IYK+F
Sbjct: 181 FDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRF 240

Query: 241 LTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRAT 300
           LTRMTR+SEFLKVAEQVGID+GDIPDL+QAPSSL++ LEQHL +LEGKK  ++  +   +
Sbjct: 241 LTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPS 300

Query: 301 TLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASP 360
            LS +                                              +  TT  SP
Sbjct: 301 PLSKS----------------------------------------------SPATTVTSP 314

Query: 361 VSTSAGGIMTAPAIDIFSTPSSS--NSTSKLPNDLLDLQQPTFHPSVHPMSTA------S 412
            ST A  I T+P +D+F+T S++   STSK  +DLLDL QP F       + A      +
Sbjct: 315 NSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDL-QPDFSSGGAAAAAAPAPPPPA 373

Query: 413 QVASTWGDPFSATVDAVDDAIPS----LNPFLTK-----SSGDVHLSISSDVSTFTTRTP 463
             A+ WGD       A   ++PS     +PF  +     ++ ++  + +S  +T T    
Sbjct: 374 GGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASASTTTTVTAV 433

Query: 464 THEMFV---GFTPSPVAQPHPSAG 484
           T E+ +    F  SP   P  S G
Sbjct: 434 TAEVDLFGDAFAASPGEAPAASEG 457



 Score =  144 bits (364), Expect = 2e-34
 Identities = 117/346 (33%), Positives = 167/346 (48%), Gaps = 52/346 (15%)

Query: 352 TSLTTAASPVSTSAGGIMTA--PAIDIF-----STPSSSNSTSKLPNDLLDLQQPTFHPS 404
           T+ T AA+  +T++    T   PA+DIF     STP  + +        +DL       S
Sbjct: 537 TAATAAATTTTTTSAATATTAPPALDIFGDLFESTPEVAAAPKPDAAPSIDLFSTDAFSS 596

Query: 405 VHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHL---SISSDVS----- 456
               ++    +S   D  S    A      + +P    SSG + L   +  S  S     
Sbjct: 597 PPQGASPVPESSLTADLLSVDAFAAPSPATTASPAKVDSSGVIDLFGDAFGSSASEPQPA 656

Query: 457 --TFTTRTPTHEMFVGF-------TPSPVAQPHPSAGLNVDFESVFG---NKSTNVIVDS 504
               ++ + + ++  GF       +PSPV  P  +  L  +FE+ FG   + S++   D 
Sbjct: 657 SQAASSSSASADLLAGFGGSFMAPSPSPVT-PAQNNLLQPNFEAAFGTTPSTSSSSSFDP 715

Query: 505 GGFDELGGLLKPTVASQNQNLPVAKLPPS------KLVSDDLDSSLANLVGNLGIGNGTT 558
             FD LG LL PT+A   Q  PV+ +PPS      K +  DLDSSLA+LVGNLGI   TT
Sbjct: 716 SVFDGLGDLLMPTMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTT 775

Query: 559 KN-DVNWSQPGEKKLTGGSNWQPKVAPTTAWNA--------------ATMAPPVMAYPAT 603
           K  D+ W+  GEKKLTGG+NWQPKVAP T W+A               +  PPV   P+ 
Sbjct: 776 KKGDLQWNA-GEKKLTGGANWQPKVAPAT-WSAGVPPSAPLQGAVPPTSSVPPVAGAPSV 833

Query: 604 TPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQI 649
              G  G+G+PP    +P+M Q  ++++QP+MRPP     V G Q+
Sbjct: 834 GQPG-AGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQL 878


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 91/390 (23%), Positives = 140/390 (35%), Gaps = 44/390 (11%)

Query: 286  EGKKIKDSTAASRATTLSNAV-------SSLASTGLSLTKVDEREKQAALEEEQARLKAL 338
            EG  +  ST   R+T L+N +       +S AST LS T VD         E  +     
Sbjct: 2678 EGSSMPTSTPGERSTPLTNILVSTTLLANSEAST-LSTTPVDTSTPVTTSAEASSSPTTA 2736

Query: 339  KEQRLK----ELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLL 394
            +   ++         P TS+  +  PV++S    ++  A+D     ++S   S  P    
Sbjct: 2737 EGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAE 2796

Query: 395  DLQQPTFHPSVHPMSTASQ------VASTWGDPFSATVDAVDDAIPSLNPFLTKSSGD-- 446
                PT  PS       S       VAS+     S T   VD + P        SS    
Sbjct: 2797 VTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTT--PVDTSTPVTTSTKASSSPTTA 2854

Query: 447  ----VHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHP-SAGLNVDFESVFGNKSTNVI 501
                V +S +S+ ST  T  P     V  + +      P    + V   +   +  T   
Sbjct: 2855 EGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE 2914

Query: 502  VDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKND 561
              S        +  P  +     +PVA    S L +  +D+            + TT   
Sbjct: 2915 GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEG 2974

Query: 562  VNW--SQPGEKKLTGGSNWQPKVAPTTAWNAATMA--PPVMAYPATT-------PTGMIG 610
             +   S PGE++ T  ++      P  +  A+T++  P   + P TT       PT   G
Sbjct: 2975 TSMPISTPGERR-TPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEG 3033

Query: 611  YGIP---PQMGSVPVMTQPTLIYSQPVMRP 637
             GIP   P  GS P+ + P  + + PV  P
Sbjct: 3034 TGIPISTPSEGSTPLTSIP--VSTTPVAIP 3061



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 82/358 (22%), Positives = 125/358 (34%), Gaps = 109/358 (30%)

Query: 286  EGKKIKDSTAASRATTLSN------AVSSLASTGLSLTKVDEREKQAALEEEQARLKALK 339
            EG  ++ ST + R T L++       V+S A + LS T VD                   
Sbjct: 2147 EGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVD------------------- 2187

Query: 340  EQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQP 399
                      P T+ T A S  +TS G  M        STP +S   S +P  ++  +  
Sbjct: 2188 -------TSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMP--VVTSEAS 2238

Query: 400  TFHPSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLS--------- 450
            T   S  P+ T++ V +T  +  S+   A   +IP+     T S G   L+         
Sbjct: 2239 TL--SATPVDTSTPV-TTSTEATSSPTTAEGTSIPTS----TLSEGTTPLTSIPVSHTLV 2291

Query: 451  ISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDEL 510
             +S+VST +T TP        T +  + P P+A                           
Sbjct: 2292 ANSEVSTLST-TPVDSNTPFTTSTEASSPPPTAE-------------------------- 2324

Query: 511  GGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEK 570
             G   PT  S   N P+ ++P S  +    ++S  +          TT  D +       
Sbjct: 2325 -GTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS----------TTPADTS------- 2366

Query: 571  KLTGGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTL 628
                         P T ++ A  + P  A   + PT     G  P + SVPV T P +
Sbjct: 2367 ------------TPVTTYSQAG-SSPTTADDTSMPTSTYSEGSTP-LTSVPVSTMPVV 2410



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 77/397 (19%), Positives = 134/397 (33%), Gaps = 51/397 (12%)

Query: 264 IPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDERE 323
           +P  ++A S L   L +    L    +     AS   + ++ +   + T   +T   E  
Sbjct: 374 LPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKT--FVTTASEAS 431

Query: 324 KQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSS 383
                 E+ +   +   +        P TS+  + +PV++S    ++   +D  +  ++S
Sbjct: 432 SSPTTAEDTSIATSTPSE-----GSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTS 486

Query: 384 NSTSKLPNDLLDLQQPTFHP----------SVHPMSTASQVASTW--------------G 419
              S  P        PT  P          SV  M  AS  AST                
Sbjct: 487 TEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSS 546

Query: 420 DPFSATVDAVDDAIPSLNPF-----LTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPS 474
           +  S++      +IP+  P      LT       L +SS+ ST +T       FV  +  
Sbjct: 547 EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSE 606

Query: 475 PVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSK 534
             +    + G ++   S +  + T +   S        L+  + AS     PV    P  
Sbjct: 607 ASSSSTTAEGTSMP-TSTYSERGTTITSMSVSTT----LVASSEASTLSTTPVDSNTPVT 661

Query: 535 LVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMA 594
             ++   SS      ++     T  +    S P    L   S      A T +      +
Sbjct: 662 TSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSE-----ASTLSTTPVDTS 716

Query: 595 PPV--MAYPATTPTGMIGYGIP---PQMGSVPVMTQP 626
            PV      +++PT   G  +P   P  GS P+ + P
Sbjct: 717 TPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMP 753



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 72/331 (21%), Positives = 114/331 (34%), Gaps = 56/331 (16%)

Query: 345  ELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQP-TFHP 403
            E++  P T     + P+ST + G      + + +TP +S++ S L    +D   P T   
Sbjct: 3082 EVSSSP-TPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTST 3140

Query: 404  SVHPMSTASQVAS-------------TWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLS 450
              H   T S+  S             T+    +  V + +D+  S  P  T +       
Sbjct: 3141 EAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTE 3200

Query: 451  ISSDVSTFTTRTPTHEMFVGFTP--------SPVAQPHPSAGLNVDFESVFGNKSTNVIV 502
             +S  +   T  PT     G TP        +PVA    S       +S      T    
Sbjct: 3201 ATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDS--NTPLTTSTE 3258

Query: 503  DSGGFDELGGLLKPTVASQNQNLPVAKLPPS-KLVSDDLDSSLANLVGNLG--------- 552
             S       G   PT      + P+  +P S   V+    S+L+    +           
Sbjct: 3259 ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQA 3318

Query: 553  -----IGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMA--PPVMAYPATT- 604
                 I +GT+     +S+ G   LT   N      P  +  A+T++  P   + P TT 
Sbjct: 3319 SSSPPIADGTSMPTSTYSE-GSTPLT---NMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374

Query: 605  ------PTGMIGYGIP---PQMGSVPVMTQP 626
                  PT   G  IP   P  G+ P+ + P
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTPLASMP 3405



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 80/383 (20%), Positives = 128/383 (33%), Gaps = 28/383 (7%)

Query: 268  SQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNA-------VSSLASTGLSLTKVD 320
            S +P      +     S EG  +  ST +  +T L +         SS AST LS T VD
Sbjct: 2542 SNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAST-LSTTPVD 2600

Query: 321  EREKQAALEEEQARLKALKEQRLK-ELAKKPHTSLTT---AASPVSTSAGGIMTAPAIDI 376
                     E  +     K+  +      +  TSLT+   +  PV++S    ++   +D 
Sbjct: 2601 TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDT 2660

Query: 377  FSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTW----GDPFSATVDAVDDA 432
             +  ++S  TS  P        PT  P        + + ST      +  + +   VD +
Sbjct: 2661 RTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTS 2720

Query: 433  IPSLNPFLTKSSGDVHLSISSDVSTFTT-RTPTHEMFVGFTP------SPVAQPHPSAGL 485
             P        SS       S  +ST +   TP   + V   P      S V+       +
Sbjct: 2721 TPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSI 2780

Query: 486  NVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLA 545
             V   +   +  T   V S           P  +    + PVA      L +  +D+S  
Sbjct: 2781 PVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTP 2840

Query: 546  NLVGNLGIGNGTTKN----DVNWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYP 601
                     + TT       ++ +  G   LT        VA + A   +T  P   + P
Sbjct: 2841 VTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLST-TPVDTSIP 2899

Query: 602  ATTPTGMIGYGIPPQMGSVPVMT 624
             TT T         +  S+P+ T
Sbjct: 2900 VTTSTEGSSSPTTAEGTSMPIST 2922



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 43/195 (22%), Positives = 71/195 (36%), Gaps = 20/195 (10%)

Query: 286  EGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKE 345
            EG  +  S   S     S   S+L++T +          + +     A   ++      E
Sbjct: 1628 EGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTE 1687

Query: 346  LAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSV 405
              + P TS+T   +PV++SA   ++   +D  +  ++S      P        P   PS 
Sbjct: 1688 -GRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSE 1746

Query: 406  H-------PMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTF 458
                    P+ST + V S+     SAT       I +  P  T +      + SS  +  
Sbjct: 1747 GTTPLTSIPVST-TPVLSSEASTLSAT------PIDTSTPVTTSTE-----ATSSPTTAE 1794

Query: 459  TTRTPTHEMFVGFTP 473
             T  PT  +  G TP
Sbjct: 1795 GTSIPTSTLSEGMTP 1809



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 74/367 (20%), Positives = 122/367 (33%), Gaps = 38/367 (10%)

Query: 286  EGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKE 345
            EG+    S   +     S+A+S L++T +  +       +A      +   ++      E
Sbjct: 1334 EGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSE 1393

Query: 346  LAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPS- 404
                P TS+  + +PV +S    ++A  +D  +  ++S   +  P     +  PT  PS 
Sbjct: 1394 -GTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSE 1452

Query: 405  ---------VHPMSTASQVASTWG-DPFSATVDAVDDAIPSLNPFLTKSSG-DVHLSISS 453
                     V     A+  AST    P  +    V     S +P  T + G  + +S  S
Sbjct: 1453 GKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSP--TPAEGTSIAISTPS 1510

Query: 454  DVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGL 513
            + ST  T  P     V  +        P         +V     T     S       G 
Sbjct: 1511 EGSTALTSIPVSTTTVASSEINSLSTTP---------AVTSTPVTTYSQASSSPTTADGT 1561

Query: 514  LKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLT 573
               T      + P+  LP S ++   + SS AN +    I    +K  V  S       T
Sbjct: 1562 SMQTSTYSEGSTPLTSLPVSTML---VVSSEANTLSTTPI---DSKTQVTASTEASSSTT 1615

Query: 574  GGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQP 633
               +      P+      T + PV   P  +P           + + PV +   +I S  
Sbjct: 1616 AEGSSMTISTPSEGSPLLT-SIPVSTTPVASPEA-------STLSTTPVDSNSPVITSTE 1667

Query: 634  VMRPPNP 640
            V   P P
Sbjct: 1668 VSSSPTP 1674



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 42/207 (20%), Positives = 82/207 (39%), Gaps = 11/207 (5%)

Query: 286  EGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKE 345
            EG+    S   S     ++A+S+L++T +  +       +A      +   ++      E
Sbjct: 862  EGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGE 921

Query: 346  LAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPS- 404
                P TS+  + +PV +S    ++A  +D  +  ++S   +  P        PT  PS 
Sbjct: 922  -GSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSE 980

Query: 405  -VHPMSTA----SQVASTWGDPFSAT-VDA---VDDAIPSLNPFLTKSSGDVHLSISSDV 455
               P+++     + VA++     S T VD+   +  +  + +P  T     +  S  S+ 
Sbjct: 981  GTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEG 1040

Query: 456  STFTTRTPTHEMFVGFTPSPVAQPHPS 482
            ST  TR P     V  + +      P+
Sbjct: 1041 STPLTRMPVSTTMVASSETSTLSTTPA 1067



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 80/376 (21%), Positives = 128/376 (34%), Gaps = 48/376 (12%)

Query: 286  EGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKE 345
            EG  +  ST   R T L         T +S++ +     +A+         +       E
Sbjct: 2973 EGTSMPISTPGERRTPL---------TSMSVSTMPVASSEASTLSRTPADTSTPVTTSTE 3023

Query: 346  LAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPT----- 400
             +  P T+  T   P+ST + G     +I + +TP +    S L    +D   P      
Sbjct: 3024 ASSSPTTAEGTGI-PISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTE 3082

Query: 401  FHPSVHPMSTASQVASTWGDPFS-------ATVDAVDDAIPSLNPFLTKSSGDVHLSI-- 451
               S  P    S   ST+ +  +       +T      AI +L+     +S  V  S   
Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEA 3142

Query: 452  -SSDVSTFTTRTPTHEMFVGFTP---SPVAQPHPSAGLNVDFESVFGNKSTNVI--VDSG 505
             SS  ++  T  PT     G TP    PV+     +  +    +   + ST V    ++ 
Sbjct: 3143 HSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEAT 3202

Query: 506  GFDELGGLLKPTVASQNQNLPVAKLPPSKLVSDDLDSSLANLVGNLGIGNG---TTKNDV 562
                  G   PT        P+  +P S   +  + SS A+++    + +    TT  + 
Sbjct: 3203 SSTTAEGTSIPTSTPSEGMTPLTSVPVS---NTPVASSEASILSTTPVDSNTPLTTSTEA 3259

Query: 563  NWSQPGEKKLTGGSNWQPKVAPTTAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPV 622
            + S P     T      P   P+      T  P      A++ T  +     P   S PV
Sbjct: 3260 SSSPP-----TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTL--STTPADTSTPV 3312

Query: 623  MTQPTLIYSQPVMRPP 638
             T     YSQ    PP
Sbjct: 3313 TT-----YSQASSSPP 3323



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 39/186 (20%), Positives = 73/186 (39%), Gaps = 16/186 (8%)

Query: 286  EGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKE 345
            EG     S   S    +S+ V++L++T +    +     +A+     A   +L      E
Sbjct: 3396 EGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSE 3455

Query: 346  LAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPT----- 400
                P + +  + +PV++S    ++   +D  +  ++S+ T+  P        PT     
Sbjct: 3456 -GSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGE 3514

Query: 401  -FHPSVHPMSTASQVASTWGDPFSAT-VDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTF 458
               P  +   + + VAS+     S T VD+        N F+T SS       +  V+T 
Sbjct: 3515 GSTPLTNMPVSTTPVASSEASTLSTTPVDS--------NTFVTSSSQASSSPATLQVTTM 3566

Query: 459  TTRTPT 464
               TP+
Sbjct: 3567 RMSTPS 3572



 Score = 29.6 bits (65), Expect = 9.1
 Identities = 33/127 (25%), Positives = 53/127 (41%), Gaps = 14/127 (11%)

Query: 286  EGKKIKDSTAASRATTLSN-------AVSSLASTGLSLTKVDEREKQAALEEEQ-----A 333
            EG  I  S  +   T L++        VSS A+T LS T VD + + A   E       A
Sbjct: 1146 EGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANT-LSTTPVDSKTQVATSTEASSPPPTA 1204

Query: 334  RLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDL 393
             + ++      E +  P TS+    +PV++S    ++   +D  +  ++S  TS  P   
Sbjct: 1205 EVTSMPTSTPGERST-PLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTA 1263

Query: 394  LDLQQPT 400
                 PT
Sbjct: 1264 EGTSLPT 1270



 Score = 29.6 bits (65), Expect = 9.1
 Identities = 42/175 (24%), Positives = 63/175 (36%), Gaps = 23/175 (13%)

Query: 296  ASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLT 355
            AS   + +  VSS A T LS T VD         E                A    T+  
Sbjct: 2459 ASMPVSTTPVVSSEAGT-LSTTPVDTSTPMTTSTE----------------ASSSPTTAE 2501

Query: 356  TAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTF-HPSVHPMSTASQV 414
                P+ST++ G     +I + +TP +S   S L    +D   P      +   +T+++ 
Sbjct: 2502 DIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEG 2561

Query: 415  ASTWGDPFSATVDAVDDAIPSLNPFL-----TKSSGDVHLSISSDVSTFTTRTPT 464
             S     +S     +     S  P       T S+  V  SI    ST T+ +PT
Sbjct: 2562 TSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPT 2616


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/136 (25%), Positives = 50/136 (36%), Gaps = 4/136 (2%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P T  TT   P +T +    T       +TPS   +T   P        PT  PS  P +
Sbjct: 1588 PPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1647

Query: 410  TASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFT----TRTPTH 465
            T +   +T   P + T  +      +  P  T  S  +  + S   +T T    T TP+ 
Sbjct: 1648 TTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS 1707

Query: 466  EMFVGFTPSPVAQPHP 481
             +    TPS    P P
Sbjct: 1708 PITTTTTPSSTTTPSP 1723



 Score = 36.6 bits (83), Expect = 0.075
 Identities = 35/132 (26%), Positives = 46/132 (34%), Gaps = 14/132 (10%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P T+ TT   P +T +  I T       +TPS   ST+  P        PT  PS  P +
Sbjct: 1424 PPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPS-PPTT 1482

Query: 410  TASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFV 469
            T S   +T   P   T  +     P   P             +S  +   T TP+     
Sbjct: 1483 TPSPPTTTTTTPPPTTTPSPPTTTPITPP-------------ASTTTLPPTTTPSPPTTT 1529

Query: 470  GFTPSPVAQPHP 481
              TP P   P P
Sbjct: 1530 TTTPPPTTTPSP 1541



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 33/135 (24%), Positives = 47/135 (34%), Gaps = 3/135 (2%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P    TT + P +T +    T       +TPS   +T   P        PT  PS    +
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT 1529

Query: 410  TASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVST---FTTRTPTHE 466
            T +   +T   P + T      +  +L P  T S      +     +T    TT TP+  
Sbjct: 1530 TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589

Query: 467  MFVGFTPSPVAQPHP 481
                 TP P   P P
Sbjct: 1590 TITTTTPPPTTTPSP 1604



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 31/130 (23%), Positives = 52/130 (40%), Gaps = 4/130 (3%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P T+ T +   ++T+     T P+    +T +   +T+  P     +  PT   ++ P +
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639

Query: 410  TASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFV 469
            T S   +T   P   T  +         P  T ++     + SS ++T T   PT  M  
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITT-TPSPPTTTM-- 1696

Query: 470  GFTPSPVAQP 479
              TPSP   P
Sbjct: 1697 -TTPSPTTTP 1705



 Score = 33.1 bits (74), Expect = 0.83
 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 7/92 (7%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P T+  T  SP +T +  I T       +TPS   +T   P+       PT   +  P +
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPT 1750

Query: 410  TASQVASTWGDPFSATVDAVDDAIPSLNPFLT 441
            T S   +T   P S T        P+ +PF T
Sbjct: 1751 TTSSPLTTTPLPPSITP-------PTFSPFST 1775



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 29/121 (23%), Positives = 46/121 (38%), Gaps = 6/121 (4%)

Query: 355  TTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQV 414
            T    P ST+     T P+    +T +   +T+  P     +  PT   ++ P +T S  
Sbjct: 1506 TPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1565

Query: 415  ASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPS 474
             +T   P   T  +         P +T ++     + S   +T TT  PT       TPS
Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT------TTPS 1619

Query: 475  P 475
            P
Sbjct: 1620 P 1620



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 35/140 (25%), Positives = 51/140 (36%), Gaps = 17/140 (12%)

Query: 350  PHTSLTT-------AASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFH 402
            P TS TT       +  P +T+     T P+    +TPS    T+  P        PT  
Sbjct: 1549 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP-------PPTTT 1601

Query: 403  PSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVST---FT 459
            PS    +T +   +T   P + T      +  +L P  T S      +     +T    T
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661

Query: 460  TRTPTHEMFVGFTPSPVAQP 479
            T TP+  +    TP P   P
Sbjct: 1662 TTTPSPPITTTTTPPPTTTP 1681



 Score = 30.0 bits (66), Expect = 7.0
 Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 7/121 (5%)

Query: 355  TTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQV 414
            TT  +P  T  G   T P     + P +  +TS  P +    Q  T   +  P++ ++ +
Sbjct: 4181 TTTVTPTPTPTG-TQTGPPTHTSTAPIAELTTSNPPPESSTPQ--TSRSTSSPLTESTTL 4237

Query: 415  ASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPS 474
             ST        ++    A PS     T +SG   LS     +T    TPT     G + +
Sbjct: 4238 LST----LPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 4293

Query: 475  P 475
            P
Sbjct: 4294 P 4294



 Score = 29.6 bits (65), Expect = 9.1
 Identities = 35/133 (26%), Positives = 51/133 (38%), Gaps = 28/133 (21%)

Query: 350  PHTSLTT-------AASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFH 402
            P TS TT       +  P +T+     T P+    +TPS   +T+  P        PT  
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP-------PPTTT 1680

Query: 403  PSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRT 462
            PS    +T S   +T   P   T  +        +P  T ++     + S   +T TT +
Sbjct: 1681 PSSPITTTPSPPTTTMTTPSPTTTPS--------SPITTTTTPSSTTTPSPPPTTMTTPS 1732

Query: 463  PTHEMFVGFTPSP 475
            PT       TPSP
Sbjct: 1733 PT------TTPSP 1739


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 39/151 (25%), Positives = 65/151 (43%), Gaps = 15/151 (9%)

Query: 351  HTS--LTTAASPVSTSAGGIMTAPAIDIFSTPSS---SNSTSKLPNDLLDLQQPTFHPSV 405
            HT+  +T   S  S +     TA A   F + SS    NS+S+ P+  +  Q P    + 
Sbjct: 2059 HTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSAT 2118

Query: 406  HPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLS---ISSDVSTFT--- 459
             P+ST +Q++S++  P  +    V   +PS +     SS  V  S   +S+ V + T   
Sbjct: 2119 TPVSTTNQLSSSF-SPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSS 2177

Query: 460  ---TRTPTHEMFVGFTPSPVAQPHPSAGLNV 487
               +   TH      + SP+    P+A   +
Sbjct: 2178 GSHSSLSTHPTTASVSASPLFPSSPAASTTI 2208



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 51/210 (24%), Positives = 81/210 (38%), Gaps = 17/210 (8%)

Query: 300  TTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAAS 359
            TTL    S+  +  ++LT     +  ++L   +              A+   TS TT  +
Sbjct: 1657 TTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTS-TTNIT 1715

Query: 360  PVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTAS----QVA 415
            P  TS G           S   SS ST+K    L      T HP V   ST S      +
Sbjct: 1716 PNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTS 1775

Query: 416  STWGDPFSATVDAVDDAIPSLNPFLTKS--SGDVHLSISSDVSTFTTRTPTHEMFVGFTP 473
            +    P + T  A    +P+  PF T S  +G   +S +  V+  + +T T        P
Sbjct: 1776 TGTRTPVAHTTSATSSRLPT--PFTTHSPPTGTTPISSTGPVTATSFQTTT------TYP 1827

Query: 474  SPVAQPHPSAGLNV-DFESVFGNKSTNVIV 502
            +P + PH +   +V  F +     ST+ ++
Sbjct: 1828 TP-SHPHTTLPTHVPSFSTSLVTPSTHTVI 1856



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 20/133 (15%)

Query: 351  HTSLTTAASPVST--SAGGIMTAPAIDIFSTPSS----SNSTSKLPNDLLDLQQPTFHPS 404
            H++ T    P +T  + G   TAP I   ++ +S    S ST+K P  L      T HP 
Sbjct: 1477 HSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPE 1536

Query: 405  VHPMSTA----SQVASTWGDPFSATVDAVDDAIPSLNPFLTKS--------SGDVHLSIS 452
            V P ST     +  ++    P + T  A     P   PF T S        S    ++ +
Sbjct: 1537 VTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPP--PFTTHSPPTGSSPFSSTGPMTAT 1594

Query: 453  SDVSTFTTRTPTH 465
            S  +T T  TP+H
Sbjct: 1595 SFKTTTTYPTPSH 1607



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 34/126 (26%), Positives = 50/126 (39%), Gaps = 23/126 (18%)

Query: 352  TSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA 411
            T  T  A P++ +  G   +P         SS ST+K    L      T HP V P ST 
Sbjct: 1886 TGSTHTAPPMTPTTSGTSQSP---------SSFSTAKTSTSLPYHTSSTHHPEVTPTSTT 1936

Query: 412  S----QVASTWGDPFSATVDAVDDAIPSLNPFLTKS--------SGDVHLSISSDVSTFT 459
            +      ++    P + T  A    +P+  PF T S        S    ++ +S  +T T
Sbjct: 1937 NITPKHTSTGTRTPVAHTTSASSSRLPT--PFTTHSPPTGSSPFSSTGPMTATSFQTTTT 1994

Query: 460  TRTPTH 465
              TP+H
Sbjct: 1995 YPTPSH 2000


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 18/147 (12%)

Query: 350  PHTSLTT--AASPVSTSAGGIMTAPAIDIFSTPSSSNS----TSKLPNDL-LDLQQPTFH 402
            PH ++T     +P  T+     T P     +TP  S++    T  LP  L  +L  PT  
Sbjct: 1299 PHPTMTPDPTTTPYPTTTPDPTTTPHP---TTPDPSSTPVITTVSLPTSLGTELSSPTLA 1355

Query: 403  PSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRT 462
            P+V P S   Q+  T   P ++T       IP+L P     S     S ++ +   +T  
Sbjct: 1356 PTVKP-SLHPQLTFTAPAPHTST-----SQIPTLEPSPALESSPSRSSTATSMDPLSTED 1409

Query: 463  --PTHEMFVGFTPSPVAQPHPSAGLNV 487
              P        TP P   PH ++ L V
Sbjct: 1410 FKPPRSQSPNLTPPPTHTPHSASDLTV 1436



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 50/178 (28%), Positives = 69/178 (38%), Gaps = 42/178 (23%)

Query: 337  ALKEQRLKELAKKPHTSLTTAAS------------PVS-TSAGGIMTAPAIDIFSTPSSS 383
            AL     +EL   PH++LT+ A+            P S T+   I+T+P   + STP SS
Sbjct: 1021 ALTSDSSRELT--PHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFAL-STPDSS 1077

Query: 384  -----------NSTSKLPNDLL-DLQQPTFHPSVHPMSTASQVASTWGD----PFSATVD 427
                            LP +L  D   P+   S+ P S     + T  D    P+S+TV 
Sbjct: 1078 VVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVS 1137

Query: 428  AVD---DAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPS 482
                  D  PS +P  T         I++   T T   PT       TP P   PHP+
Sbjct: 1138 EYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPT-------TPHPTTTPHPT 1188


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 37.4 bits (85), Expect = 0.044
 Identities = 29/83 (34%), Positives = 37/83 (44%), Gaps = 13/83 (15%)

Query: 576 SNWQPKVAPTTAWNAATMAP---------PVMAYPATTPTGMIGYGIPPQMGSVPVMTQP 626
           S+ +P  AP TAW A   AP         P  A PA +P   + +G PP    VP    P
Sbjct: 49  SHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPAS-LAFGPPPDFSPVPAPPGP 107

Query: 627 -TLIYSQPVMRPPNPFGPVSGAQ 648
              + +QP+  P  P  P  GAQ
Sbjct: 108 GPGLLAQPLGGPGTPSSP--GAQ 128


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 37.0 bits (84), Expect = 0.057
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 19/140 (13%)

Query: 210 AYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ 269
           A  E  I  L++  D  + + +E +D YKK L  +          E+V + +GD   LS+
Sbjct: 623 AEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLK---------EKVSLLQGD---LSE 670

Query: 270 APSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALE 329
             +SLLD L++H +SL    +K     SR  TL  A+       L +    ++  +AALE
Sbjct: 671 KEASLLD-LKEHASSLASSGLKKD---SRLKTLEIALEQKKEECLKMESQLKKAHEAALE 726

Query: 330 EEQARLKALKEQRLKELAKK 349
              AR       R++ L ++
Sbjct: 727 ---ARASPEMSDRIQHLERE 743



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 70/327 (21%), Positives = 126/327 (38%), Gaps = 37/327 (11%)

Query: 41  HLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERF------- 93
           HL+ L++   + N  + +     FE   +S+     +++I      +   ER        
Sbjct: 345 HLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404

Query: 94  IQYLASRNTLFNLSNFLDKSGLQGY-DMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGA 152
           IQ L S   L       +   ++ Y   S F++     L E+  S      +  K   G 
Sbjct: 405 IQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGL 464

Query: 153 DGVMRTMNTEKLLKTVPII--QNQMDALLD--------FNVNSNELTNGVINAAFMLLFK 202
              +  +  E   K   ++  Q +++ L +          V    LT     AA +    
Sbjct: 465 QAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEV 524

Query: 203 DAIRLFAAYNEGIINLLEKYF-DMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQ-VGID 260
           DA+RL     E ++N   K   DM + +  +  +I+         + + L V E+ V + 
Sbjct: 525 DALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD--------LKDMLDVKERKVNVL 576

Query: 261 RGDIPDLSQA---PSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLT 317
           +  I +L +        + +L++ + SL+       TA    TTL  A++    T   L 
Sbjct: 577 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTAL---TTLEEALAEKERTIERLK 633

Query: 318 KV---DEREKQAALEEEQARLKALKEQ 341
           +    DEREKQ  ++  +  LK LKE+
Sbjct: 634 EQRDRDEREKQEEIDNYKKDLKDLKEK 660


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 37.0 bits (84), Expect = 0.057
 Identities = 40/140 (28%), Positives = 65/140 (46%), Gaps = 19/140 (13%)

Query: 210 AYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQ 269
           A  E  I  L++  D  + + +E +D YKK L  +          E+V + +GD   LS+
Sbjct: 595 AEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLK---------EKVSLLQGD---LSE 642

Query: 270 APSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALE 329
             +SLLD L++H +SL    +K     SR  TL  A+       L +    ++  +AALE
Sbjct: 643 KEASLLD-LKEHASSLASSGLKKD---SRLKTLEIALEQKKEECLKMESQLKKAHEAALE 698

Query: 330 EEQARLKALKEQRLKELAKK 349
              AR       R++ L ++
Sbjct: 699 ---ARASPEMSDRIQHLERE 715



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 67/313 (21%), Positives = 125/313 (39%), Gaps = 37/313 (11%)

Query: 41  HLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASR 100
           HL+ L++   + N  + +     FE   +S+     +++I      +   ER ++ L   
Sbjct: 345 HLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404

Query: 101 NTLFNLSNFLD-KSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTM 159
             +   +  L  +   +        R +S+++  K    +Q               +   
Sbjct: 405 IQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQE--------------LSRK 450

Query: 160 NTEKL-LKT-VPIIQNQM-DALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGII 216
           +TE L L+T +  + NQ  D+     V    LT     AA +    DA+RL     E ++
Sbjct: 451 DTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETML 510

Query: 217 NLLEKYF-DMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQ-VGIDRGDIPDLSQA---P 271
           N   K   DM + +  +  +I+         + + L V E+ V + +  I +L +     
Sbjct: 511 NKKTKQIQDMAEEKGTQAGEIHD--------LKDMLDVKERKVNVLQKKIENLQEQLRDK 562

Query: 272 SSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKV---DEREKQAAL 328
              + +L++ + SL+       TA    TTL  A++    T   L +    DEREKQ  +
Sbjct: 563 EKQMSSLKERVKSLQADTTNTDTAL---TTLEEALAEKERTIERLKEQRDRDEREKQEEI 619

Query: 329 EEEQARLKALKEQ 341
           +  +  LK LKE+
Sbjct: 620 DNYKKDLKDLKEK 632


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 58/240 (24%), Positives = 85/240 (35%), Gaps = 20/240 (8%)

Query: 237 YKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAA 296
           Y KFL + T  SE     +        +  L    S L D  + HLA LE     +  A 
Sbjct: 332 YVKFLKQATDNSEISSATK--------LRQLKAFKSVLADIKKAHLA-LEEDLNSEFRAM 382

Query: 297 SRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTT 356
                  N            TK  + EK  ALE++       K  R +  ++  H ++ T
Sbjct: 383 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT 442

Query: 357 AASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVAS 416
                + S GG               +N++  L  D++ +           + TA +V S
Sbjct: 443 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS 502

Query: 417 T---WGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTP 473
           +    GD  S T   V+ +   LN     SS D    I S     TT   T E++V  TP
Sbjct: 503 SVDHQGDGSSGTEQEVESSSVKLN----ISSKDNRGGIKSK----TTAKVTKELYVKLTP 554


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 58/240 (24%), Positives = 85/240 (35%), Gaps = 20/240 (8%)

Query: 237 YKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAA 296
           Y KFL + T  SE     +        +  L    S L D  + HLA LE     +  A 
Sbjct: 370 YVKFLKQATDNSEISSATK--------LRQLKAFKSVLADIKKAHLA-LEEDLNSEFRAM 420

Query: 297 SRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTT 356
                  N            TK  + EK  ALE++       K  R +  ++  H ++ T
Sbjct: 421 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT 480

Query: 357 AASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVAS 416
                + S GG               +N++  L  D++ +           + TA +V S
Sbjct: 481 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS 540

Query: 417 T---WGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTP 473
           +    GD  S T   V+ +   LN     SS D    I S     TT   T E++V  TP
Sbjct: 541 SVDHQGDGSSGTEQEVESSSVKLN----ISSKDNRGGIKSK----TTAKVTKELYVKLTP 592


>gi|206597509 HIV-1 Rev binding protein isoform 4 [Homo sapiens]
          Length = 522

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 38/138 (27%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 371 APAIDIFSTPSSSNSTSKLPNDLLDLQQ-------------PTFHPSVHPMSTASQVAST 417
           AP   + S PS S+++S     L +L                T + S +   T   VAS 
Sbjct: 315 APVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASA 374

Query: 418 WGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTR----------TPTHEM 467
              P S++V A   A PS NPF+  +      S++S  + F T           T +  M
Sbjct: 375 QTQPASSSVPAPFGATPSTNPFVAAAGP----SVASSTNPFQTNARGATAATFGTASMSM 430

Query: 468 FVGF-TPSPVAQPHPSAG 484
             GF TP+P + P   +G
Sbjct: 431 PTGFGTPAPYSLPTSFSG 448


>gi|206597507 HIV-1 Rev binding protein isoform 3 [Homo sapiens]
          Length = 560

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 38/138 (27%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 371 APAIDIFSTPSSSNSTSKLPNDLLDLQQ-------------PTFHPSVHPMSTASQVAST 417
           AP   + S PS S+++S     L +L                T + S +   T   VAS 
Sbjct: 355 APVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASA 414

Query: 418 WGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTR----------TPTHEM 467
              P S++V A   A PS NPF+  +      S++S  + F T           T +  M
Sbjct: 415 QTQPASSSVPAPFGATPSTNPFVAAAGP----SVASSTNPFQTNARGATAATFGTASMSM 470

Query: 468 FVGF-TPSPVAQPHPSAG 484
             GF TP+P + P   +G
Sbjct: 471 PTGFGTPAPYSLPTSFSG 488


>gi|206597505 HIV-1 Rev binding protein isoform 1 [Homo sapiens]
          Length = 584

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 38/138 (27%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 371 APAIDIFSTPSSSNSTSKLPNDLLDLQQ-------------PTFHPSVHPMSTASQVAST 417
           AP   + S PS S+++S     L +L                T + S +   T   VAS 
Sbjct: 379 APVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASA 438

Query: 418 WGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTR----------TPTHEM 467
              P S++V A   A PS NPF+  +      S++S  + F T           T +  M
Sbjct: 439 QTQPASSSVPAPFGATPSTNPFVAAAGP----SVASSTNPFQTNARGATAATFGTASMSM 494

Query: 468 FVGF-TPSPVAQPHPSAG 484
             GF TP+P + P   +G
Sbjct: 495 PTGFGTPAPYSLPTSFSG 512


>gi|38570132 HIV-1 Rev binding protein isoform 2 [Homo sapiens]
          Length = 562

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 38/138 (27%), Positives = 56/138 (40%), Gaps = 28/138 (20%)

Query: 371 APAIDIFSTPSSSNSTSKLPNDLLDLQQ-------------PTFHPSVHPMSTASQVAST 417
           AP   + S PS S+++S     L +L                T + S +   T   VAS 
Sbjct: 355 APVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASA 414

Query: 418 WGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTR----------TPTHEM 467
              P S++V A   A PS NPF+  +      S++S  + F T           T +  M
Sbjct: 415 QTQPASSSVPAPFGATPSTNPFVAAAGP----SVASSTNPFQTNARGATAATFGTASMSM 470

Query: 468 FVGF-TPSPVAQPHPSAG 484
             GF TP+P + P   +G
Sbjct: 471 PTGFGTPAPYSLPTSFSG 488


>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
            [Homo sapiens]
          Length = 1180

 Score = 36.2 bits (82), Expect = 0.097
 Identities = 51/217 (23%), Positives = 81/217 (37%), Gaps = 32/217 (14%)

Query: 291  KDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKP 350
            K S+AASR+++L N      S+G +L+  + +    A  E+ +R + L ++    + KK 
Sbjct: 851  KSSSAASRSSSLVNLWKRRGSSGETLSS-NGKSVTWAQNEKSSRGQHLWQRLSIHINKKE 909

Query: 351  HTSLTTAASP---------------VSTSAGGI-MTAPAIDIFSTPSSSNSTSKLPNDLL 394
            + + T    P                  SAGG+  T  A    + P    S    P  L 
Sbjct: 910  NPNQTAVIKPFPKSTESRGLGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALY 969

Query: 395  DLQQPTFH-------PSVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDV 447
            D+ +   H        S  P+ST S  A         +    DD +PSL+      S   
Sbjct: 970  DVAEAEEHFPAPARPRSPSPISTLSHRA--------GSASRTDDDVPSLHSEPVARSSSS 1021

Query: 448  HLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAG 484
              S+   +S+  TR   +   +       A P P  G
Sbjct: 1022 QGSLMEQISSVVTRFTANISELNSMMLSTAAPSPGVG 1058


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 40/148 (27%), Positives = 57/148 (38%), Gaps = 24/148 (16%)

Query: 444  SGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSA-------------------G 484
            +G++H  + S       R+P    FVG TPSP+    P A                   G
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVG-TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHG 2561

Query: 485  LNVDF---ESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKL-PPSKLVSDDL 540
            +N  F    ++   +STN  V +G F   G  L P+  S  ++  ++ L PPS L     
Sbjct: 2562 INSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621

Query: 541  DSSLANLVGNLGIGNGTTKNDVNWSQPG 568
            D SL  L       +G T        PG
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPG 2649


>gi|7661968 epsin 4 [Homo sapiens]
          Length = 625

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 132/640 (20%), Positives = 225/640 (35%), Gaps = 121/640 (18%)

Query: 20  SAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERT---TNSSWVVVF 76
           S +   V +AT  +  GP  + +  + + T  M    P+L + L+ R       +W  V+
Sbjct: 22  SEIESKVREATNDDPWGPSGQLMGEIAKATF-MYEQFPELMNMLWSRMLKDNKKNWRRVY 80

Query: 77  KSLITTHHLMVYGNERFIQYLASRNTLFNLS-----NFLDKSGLQGYDMSTFIRRYSRYL 131
           KSL+   +L+  G+ER +   ++R  +++L      +F+D+    G D    IR+  + L
Sbjct: 81  KSLLLLAYLIRNGSERVV--TSAREHIYDLRSLENYHFVDE---HGKDQGINIRQKVKEL 135

Query: 132 NEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNG 191
            E A    ++  +  K K+  D  +                          V+S+ +   
Sbjct: 136 VEFAQDDDRLREERKKAKKNKDKYV-------------------------GVSSDSV--- 167

Query: 192 VINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKK---FLTRMTRIS 248
                                 G     E+Y    K++  E  D  K    F  ++  +S
Sbjct: 168 ----------------------GGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELS 205

Query: 249 EFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSS 308
           + +       I +    D   +P    D+ E+  A   G+  K        T  +  +  
Sbjct: 206 DKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKAR-RGRSPKGEFKDEEETVTTKHIHI 264

Query: 309 LASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSA-GG 367
             +T  + T    R K+ A   +   L A       + +   + S  T  S V TS    
Sbjct: 265 TQATETTTT----RHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSS 320

Query: 368 IMTAPAIDIF-STPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTASQVASTWGDPFSATV 426
             +   +D+F  T  S+  ++ L     D        S     TA+     +GD +SA  
Sbjct: 321 KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGD-WSAFN 379

Query: 427 DAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMFVGFTPSPVAQPHPSAGLN 486
            A    + S   F   +S                  P  E+  G + S +  P  ++  +
Sbjct: 380 QAPSGPVASSGEFFGSAS-----------------QPAVELVSG-SQSALGPPPAASNSS 421

Query: 487 VDFESVFGNKSTNVIVDSGGFDELG----GLLKPTVASQNQNL---PVAKLPPSKLVSDD 539
             F+ +  +++T     S  F  +     GL  P   SQN ++    V+K  PS      
Sbjct: 422 DLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPS 481

Query: 540 LDSSLANLVGNLGIGN------GTTKNDVNWSQP--------GEKKLTGGSNWQPKVAPT 585
           ++ SL NL+  +           T     N  QP        G   L+  SN  P V P 
Sbjct: 482 VNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLP-VRPQ 540

Query: 586 TAWNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQ 625
           T  NA    P  M+ P    TG +G      +G+ P+M Q
Sbjct: 541 T--NALIGGPMPMSMP-NVMTGTMGMA---PLGNTPMMNQ 574


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 90/415 (21%), Positives = 152/415 (36%), Gaps = 45/415 (10%)

Query: 246 RISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNA 305
           R+S   +  EQ  + R +     Q  SSL   +EQ  AS  G  IK   +AS     ++ 
Sbjct: 561 RVSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTG--IKQLPSASTGIPTAST 618

Query: 306 VSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSA 365
            S+  ST +   +  E ++   L+ +Q  +  L +           T  +   S V T +
Sbjct: 619 TSASVSTQVE-PEEPEADQHQQLQYQQPSISVLSD----------GTVDSGQGSSVFTES 667

Query: 366 GGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHP-SVHPMSTASQVASTWGDPFSA 424
             + +   +   S    ++ST  +P  +    Q    P  V+P S+ +Q   + G P S+
Sbjct: 668 -RVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQ-GQSQGQPSSS 725

Query: 425 TVDAVDDAIPSLNP---------FLTKSSGDVHLSISSDVSTFTTRTPTHE--------M 467
           ++  V  + P  +P            + +    LS +S  S  TT  P  +         
Sbjct: 726 SLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTAQPVSQPQAPQVLPQ 785

Query: 468 FVGFTPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGG-FDELGGLLKPTVASQNQNLP 526
                  PV+QP P+  +  + +     + + V V SG  F  +G  L   +  Q    P
Sbjct: 786 VSAGKQLPVSQPVPT--IQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQ---YP 840

Query: 527 VAKLPPSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPGEKKLTGGSNWQPKVAPTT 586
           V+++P S        +  ++L   +  G  T       S      + G S   P   PT 
Sbjct: 841 VSQIPISTPHVSTAQTGFSSLPITMAAGI-TQPLLTLASSATTAAIPGVSTVVPSQLPTL 899

Query: 587 AWNAATMAPPVMAYPATTPTGMIGYGIPPQMG---SVPVMTQPTLIYSQPVMRPP 638
                 +  P   +P      +   GIP  +G    VP+ +   L    P   PP
Sbjct: 900 LQPVTQL--PSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPP 952


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 41/128 (32%), Positives = 53/128 (41%), Gaps = 9/128 (7%)

Query: 350  PHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
            P TS T A +  +TSA    T  A    +T +S  ST+  P +       T   S    S
Sbjct: 1891 PQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTTS 1950

Query: 410  -TASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEMF 468
             T++   ST   P S+T  A   +  S     T SS     S +S  +T TT  P     
Sbjct: 1951 ITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQT--STTSAPTTSTTSGP----- 2003

Query: 469  VGFTPSPV 476
             G TPSPV
Sbjct: 2004 -GTTPSPV 2010


>gi|239752529 PREDICTED: similar to mucin [Homo sapiens]
          Length = 594

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 23/150 (15%)

Query: 352 TSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA 411
           TS  T+   +S S     +     I +T ++S+ST  L + +         PS+  + T+
Sbjct: 242 TSSITSTETISHSTPSFSSL----ITATKTTSHSTPSLTSLITTTNTSHSTPSLTSLVTS 297

Query: 412 SQVASTWGDPFSA---TVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTHEM- 467
           ++ AS     F++   T++A   + PSL   +T +    H + S    T  T + +H   
Sbjct: 298 TETASHSTPSFTSLITTIEATSHSTPSLTSSITTTGTTSHSTPSFTYLTTITESTSHSTP 357

Query: 468 ---------------FVGFTPSPVAQPHPS 482
                           +GFTPS ++   PS
Sbjct: 358 SLTSAITTTETMSHSILGFTPSIISPSTPS 387



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 8/116 (6%)

Query: 353 SLTTAASPVSTSAGGIMT-APAIDIFSTPS--SSNSTSKLPNDLLDLQQPTFHPSVHPMS 409
           SLT+A +   T +  I+   P+I   STPS  S  +T++ P+       P+F  S+    
Sbjct: 358 SLTSAITTTETMSHSILGFTPSIISPSTPSYISLIATTETPSH----STPSFPSSITTTQ 413

Query: 410 TASQVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTRTPTH 465
           +AS    +     S T +A+  +IP     +T +    HL         TT+T +H
Sbjct: 414 SASHSTPSLTSAISTT-EAMSHSIPVFTSLITTTETTSHLPPRFTSLITTTKTTSH 468


>gi|239753106 PREDICTED: similar to hCG1817845 [Homo sapiens]
          Length = 1090

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 44/182 (24%), Positives = 65/182 (35%), Gaps = 13/182 (7%)

Query: 288 KKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELA 347
           K  +D+    R  T+  A     +T     K   R    A  + QAR   L+       A
Sbjct: 235 KHSRDARVRIRGVTVVGAAQGSVATHSWEAKDGPRATGPAQPKIQARFLLLQSHHSDTRA 294

Query: 348 KKPHTSLTTAASPVSTSAGGIMTAPA----IDIFSTPSSSNSTSKLPNDLLDLQQPTFHP 403
               T   T  +P   S  G++T PA      +F      +  S      L +  PT   
Sbjct: 295 LPTDTGTLTIPAPTRGSDTGMLTVPATTRGCSLFQHRHGDDHYSSTDTGTLTIPAPTRGT 354

Query: 404 SVHPMSTASQVASTWGDPFSATVDAVDDAIPSLNPFLTK-SSGDVHLSISSDVSTFTTRT 462
            +  ++  +    T  DP + T+ A     P+    L +   GD H S S+D  T T   
Sbjct: 355 DMGTLTIPAPTRDT--DPGTLTIPA-----PTWGRSLFQHXHGDAHYS-STDTGTLTIPA 406

Query: 463 PT 464
           PT
Sbjct: 407 PT 408


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 34.7 bits (78), Expect = 0.28
 Identities = 38/122 (31%), Positives = 58/122 (47%), Gaps = 21/122 (17%)

Query: 261 RGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVD 320
           +  I +LSQA   L  A + H A L  +    ++  S  TTL NA        L+  K  
Sbjct: 472 QSSISNLSQAKEELEQASQAHGARLTAQV---ASLTSELTTL-NATIQQQDQELAGLKQQ 527

Query: 321 EREKQAAL-----EEEQA------RLKAL------KEQRLKELAKKPHTSLTTAASPVST 363
            +EKQA L     ++EQA      +++ L      KEQ+LKE+A+K   +    A  ++T
Sbjct: 528 AKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLAT 587

Query: 364 SA 365
           +A
Sbjct: 588 AA 589


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 28/116 (24%), Positives = 50/116 (43%), Gaps = 19/116 (16%)

Query: 288 KKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELA 347
           KK K +T     T      ++   T  + TK  E+EK+   E+E+ + K  ++++ K+  
Sbjct: 44  KKKKTTTKKKTTTKTKKRTTTTKKTTTTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKK 103

Query: 348 KKPH------------------TSLTTAASPVSTSAGGIMTAPAIDIF-STPSSSN 384
           KK                    + +TTAA+      G ++ A  + I  S+PS S+
Sbjct: 104 KKKKKKKKKLNAKVCGLEIASWSEMTTAAAGEGEEQGSMVQAAGVSISNSSPSRSD 159


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 64/281 (22%), Positives = 101/281 (35%), Gaps = 29/281 (10%)

Query: 353  SLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTAS 412
            S  T   P ST++ GI+ A      ST S   + S   +    LQ  +     HP ST  
Sbjct: 2644 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPAST-- 2701

Query: 413  QVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTR-TPTHEMFVGF 471
               +T   P +AT    +      +P  T ++   H   SS  S  + + T  H      
Sbjct: 2702 --HTTPSPPSTATAPVEESTTYHRSPGSTPTT---HFPASSTTSGHSEKSTIFHSSPDAS 2756

Query: 472  TPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLP 531
              +P +    ++G      S     ST +    G     G     T    +   P   L 
Sbjct: 2757 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 2816

Query: 532  PSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPG--EKKLTGGSNWQPKVA--PTTA 587
            P+ + S             LG+G  +T    + SQPG     ++  S   P ++   TT 
Sbjct: 2817 PASMTS-------------LGVGEEST---TSRSQPGSTHSTVSPASTTTPGLSEESTTV 2860

Query: 588  WNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTL 628
            ++++  +     +P +T T + G   P    S P  T  TL
Sbjct: 2861 YSSSPGSTETTVFPRSTTTSVRGEE-PTTFHSRPASTHTTL 2900



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 64/281 (22%), Positives = 101/281 (35%), Gaps = 29/281 (10%)

Query: 353  SLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTAS 412
            S  T   P ST++ GI+ A      ST S   + S   +    LQ  +     HP ST  
Sbjct: 1087 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST-- 1144

Query: 413  QVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTR-TPTHEMFVGF 471
               +T   P +AT    +      +P  T ++   H   SS  S  + + T  H      
Sbjct: 1145 --HTTPSPPSTATAPVEESTTYHRSPGSTPTT---HFPASSTTSGHSEKSTIFHSSPDAS 1199

Query: 472  TPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLP 531
              +P +    ++G      S     ST +    G     G     T    +   P   L 
Sbjct: 1200 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 1259

Query: 532  PSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPG--EKKLTGGSNWQPKVA--PTTA 587
            P+ + S             LG+G  +T    + SQPG     ++  S   P ++   TT 
Sbjct: 1260 PASMTS-------------LGVGEEST---TSRSQPGSTHSTVSPASTTTPGLSEESTTV 1303

Query: 588  WNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTL 628
            ++++  +     +P +T T + G   P    S P  T  TL
Sbjct: 1304 YSSSRGSTETTVFPHSTTTSVHGEE-PTTFHSRPASTHTTL 1343



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 64/281 (22%), Positives = 100/281 (35%), Gaps = 29/281 (10%)

Query: 353  SLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTAS 412
            S  T   P ST++ GI+ A      ST S   + S   +    LQ  +     HP ST  
Sbjct: 2170 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST-- 2227

Query: 413  QVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTR-TPTHEMFVGF 471
               +T   P +AT    +      +P  T ++   H   SS  S  + + T  H      
Sbjct: 2228 --HTTPSPPSTATAPVEESTTYHRSPGSTPTT---HFPASSTTSGHSEKSTIFHSSPDAS 2282

Query: 472  TPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLP 531
              +P +    ++G      S     ST +    G     G     T    +   P   L 
Sbjct: 2283 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 2342

Query: 532  PSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPG--EKKLTGGSNWQPKVA--PTTA 587
            P+ + S             LG+G  +T    + SQPG     ++  S   P ++   TT 
Sbjct: 2343 PASMTS-------------LGVGEEST---TSRSQPGSTHSTVSPASTTTPGLSEESTTV 2386

Query: 588  WNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTL 628
            ++++  +     +P T  T + G   P    S P  T  TL
Sbjct: 2387 YSSSPGSTETTVFPRTPTTSVRGEE-PTTFHSRPASTHTTL 2426



 Score = 32.0 bits (71), Expect = 1.8
 Identities = 63/281 (22%), Positives = 100/281 (35%), Gaps = 29/281 (10%)

Query: 353  SLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTAS 412
            S  T   P ST++ GI+ A      ST S   + S   +    LQ  +     HP ST  
Sbjct: 3727 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST-- 3784

Query: 413  QVASTWGDPFSATVDAVDDAIPSLNPFLTKSSGDVHLSISSDVSTFTTR-TPTHEMFVGF 471
               +T   P +AT    +      +P  T ++   H   SS  S  + + T  H      
Sbjct: 3785 --HTTPSPPSTATAPVEESTTYHRSPGSTPTT---HFPASSTTSGHSEKSTIFHSSPDAS 3839

Query: 472  TPSPVAQPHPSAGLNVDFESVFGNKSTNVIVDSGGFDELGGLLKPTVASQNQNLPVAKLP 531
              +P +    ++G      S     ST +    G     G     T    +   P   L 
Sbjct: 3840 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 3899

Query: 532  PSKLVSDDLDSSLANLVGNLGIGNGTTKNDVNWSQPG--EKKLTGGSNWQPKVA--PTTA 587
            P+ + S             LG+G  +T    + SQPG     ++  S   P ++   TT 
Sbjct: 3900 PASMTS-------------LGVGEEST---TSRSQPGSTHSTVSPASTTTPGLSEESTTV 3943

Query: 588  WNAATMAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTL 628
            ++++  +     +P +T T  +    P    S P  T  TL
Sbjct: 3944 YSSSPGSTETTVFPRSTTTS-VRREEPTTFHSRPASTHTTL 3983


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 29/130 (22%), Positives = 63/130 (48%), Gaps = 15/130 (11%)

Query: 226  KKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASL 285
            K+++ ++ L   + F   +  + E+L  AEQ    RG +PD ++A  SL+D  ++ +  +
Sbjct: 5304 KQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKV 5363

Query: 286  EGKKIKDSTAASRA------------TTLSNAVSSLAS---TGLSLTKVDEREKQAALEE 330
            E K++  ++A +              TT+ + ++ + +     L+  K  ++  + AL E
Sbjct: 5364 EEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSE 5423

Query: 331  EQARLKALKE 340
              A  + L+E
Sbjct: 5424 LVANAELLEE 5433


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 29/130 (22%), Positives = 63/130 (48%), Gaps = 15/130 (11%)

Query: 226  KKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASL 285
            K+++ ++ L   + F   +  + E+L  AEQ    RG +PD ++A  SL+D  ++ +  +
Sbjct: 4802 KQSRLEQALKQAEVFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKV 4861

Query: 286  EGKKIKDSTAASRA------------TTLSNAVSSLAS---TGLSLTKVDEREKQAALEE 330
            E K++  ++A +              TT+ + ++ + +     L+  K  ++  + AL E
Sbjct: 4862 EEKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETALSE 4921

Query: 331  EQARLKALKE 340
              A  + L+E
Sbjct: 4922 LVANAELLEE 4931


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 35/148 (23%), Positives = 67/148 (45%), Gaps = 14/148 (9%)

Query: 231  KEGLDIYKKFLTRMTRISEFLKVAEQVG---IDRGDIPDLSQAP--------SSLLDALE 279
            K  L IYKKFL +   ++  LK  +  G   ++    P  S+ P         SLL  L+
Sbjct: 2179 KAQLKIYKKFLKKAQDLTSLLKELKSQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQ 2238

Query: 280  QHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALK 339
              + +L+G   +  +     T L+  + + +   +S +  D+   Q A+EE+  +L+ L+
Sbjct: 2239 DSVQNLDGHVREHDSYQVCVTDLNTTLDNFSKEFVSFS--DKPVDQIAVEEKLQKLQELE 2296

Query: 340  EQ-RLKELAKKPHTSLTTAASPVSTSAG 366
             +  L++   K   +L  +    ++S G
Sbjct: 2297 NRLSLQDGTLKKILALAKSVKQNTSSVG 2324


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
            [Homo sapiens]
          Length = 6885

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 35/148 (23%), Positives = 67/148 (45%), Gaps = 14/148 (9%)

Query: 231  KEGLDIYKKFLTRMTRISEFLKVAEQVG---IDRGDIPDLSQAP--------SSLLDALE 279
            K  L IYKKFL +   ++  LK  +  G   ++    P  S+ P         SLL  L+
Sbjct: 2179 KAQLKIYKKFLKKAQDLTSLLKELKSQGNYLLECTKNPSFSEEPWLEIKHLHESLLQQLQ 2238

Query: 280  QHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALK 339
              + +L+G   +  +     T L+  + + +   +S +  D+   Q A+EE+  +L+ L+
Sbjct: 2239 DSVQNLDGHVREHDSYQVCVTDLNTTLDNFSKEFVSFS--DKPVDQIAVEEKLQKLQELE 2296

Query: 340  EQ-RLKELAKKPHTSLTTAASPVSTSAG 366
             +  L++   K   +L  +    ++S G
Sbjct: 2297 NRLSLQDGTLKKILALAKSVKQNTSSVG 2324


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,792,125
Number of Sequences: 37866
Number of extensions: 1102435
Number of successful extensions: 4316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 4117
Number of HSP's gapped (non-prelim): 345
length of query: 652
length of database: 18,247,518
effective HSP length: 109
effective length of query: 543
effective length of database: 14,120,124
effective search space: 7667227332
effective search space used: 7667227332
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.