Search of human proteins with 56605981

Search of human proteins with 56605981

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56605981 tripartite motif-containing 72 [Homo sapiens]
         (477 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56605981 tripartite motif-containing 72 [Homo sapiens]             965   0.0  
gi|30023818 tripartite motif protein 50A [Homo sapiens]               273   2e-73
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    204   1e-52
gi|217035095 tripartite motif-containing 62 [Homo sapiens]            196   4e-50
gi|15208660 tripartite motif protein 21 [Homo sapiens]                191   1e-48
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            190   2e-48
gi|5730009 ret finger protein [Homo sapiens]                          189   5e-48
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   188   8e-48
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   187   2e-47
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   181   1e-45
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             181   2e-45
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   168   9e-42
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    168   9e-42
gi|37622899 ring finger protein 137 [Homo sapiens]                    167   2e-41
gi|22749269 ring finger protein 129 [Homo sapiens]                    164   1e-40
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   162   8e-40
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            157   2e-38
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    157   3e-38
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    157   3e-38
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   151   1e-36
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   150   3e-36
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              147   2e-35
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   146   5e-35
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   144   1e-34
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             143   3e-34
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   139   7e-33
gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]   135   1e-31
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            134   2e-31
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi...   134   2e-31
gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]   130   3e-30

>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score =  965 bits (2495), Expect = 0.0
 Identities = 477/477 (100%), Positives = 477/477 (100%)

Query: 1   MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPT 60
           MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPT
Sbjct: 1   MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPT 60

Query: 61  RPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLL 120
           RPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLL
Sbjct: 61  RPQALSTNLQLARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLL 120

Query: 121 PAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMR 180
           PAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMR
Sbjct: 121 PAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMR 180

Query: 181 VFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFLMK 240
           VFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFLMK
Sbjct: 181 VFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFLMK 240

Query: 241 YCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHP 300
           YCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHP
Sbjct: 241 YCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHP 300

Query: 301 SLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALG 360
           SLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALG
Sbjct: 301 SLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALG 360

Query: 361 VIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFG 420
           VIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFG
Sbjct: 361 VIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFG 420

Query: 421 DGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPEGAEA 477
           DGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPEGAEA
Sbjct: 421 DGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPEGAEA 477


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score =  273 bits (698), Expect = 2e-73
 Identities = 162/484 (33%), Positives = 246/484 (50%), Gaps = 35/484 (7%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67
           L   L CP+CL++F  P+  +CGHS+C+ CL  V+     D  + CP C+      +   
Sbjct: 10  LEDWLQCPICLEVFKEPLMLQCGHSYCKGCL--VSLSCHLDAELRCPVCRQAVDGSSSLP 67

Query: 68  NLQLARLVEGLAQVPQGH---CEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPAAE 124
           N+ LAR++E L          C  H +PLS++CE+D+ L+CG+C  LGSH+ H + P + 
Sbjct: 68  NVSLARVIEALRLPGDPEPKVCVHHRNPLSLFCEKDQELICGLCGLLGSHQHHPVTPVST 127

Query: 125 AHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLA 184
            ++R+K +L     +L++   + ++ +A L +    +      F   +  +  +      
Sbjct: 128 VYSRMKEELAALISELKQEQKKVDELIAKLVNNRTRIVNESDVFSWVIRREFQE------ 181

Query: 185 ALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQ-------LRQMEKVLEEVADKPQTEF 237
            L   +D E  R     G   R  + SL+  LEQ       L Q E VLE+  ++   +F
Sbjct: 182 -LHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQGTRERLAQAECVLEQFGNEDHHKF 240

Query: 238 LMKYCLVTSRLQKILAESPPPARLDIQLPIIS-------DDFKFQVWRKMFRALMPALEE 290
           + K+  + SR     AE P    L+     IS        D K  VW+++FR ++PA E 
Sbjct: 241 IRKFHSMASR-----AEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEP 295

Query: 291 LTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVD 350
           L  DP++AHP L +S     V+C    A      P +FD +  V+A +  S G HYWEV 
Sbjct: 296 LKLDPATAHPLLELSKGNTVVQCG-LLAQRRASQPERFDYSTCVLASRGFSCGRHYWEVV 354

Query: 351 VGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRP 410
           VG K  W LGVI   A R+G+L+  P  G+WL+GL+EG++ EA    + P  +      P
Sbjct: 355 VGSKSDWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAG---HP 411

Query: 411 TRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLV 470
            RIGLYL +  G L+F+DA   D L PL+ F       +YP  D CWH++G N+ P++L 
Sbjct: 412 HRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSLPMVLP 471

Query: 471 GPEG 474
            P G
Sbjct: 472 PPSG 475


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  204 bits (519), Expect = 1e-52
 Identities = 146/501 (29%), Positives = 213/501 (42%), Gaps = 74/501 (14%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGT----------VLCPCCQ 57
           L  E +C +CL+LF  PV+ ECGHSFCRAC+GR    P A             + CP C+
Sbjct: 23  LQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCR 82

Query: 58  APTRPQALSTNLQLARLVEGL-------------------AQVPQGHCEEHLDPLSIYCE 98
            P RP  L  N QLA +   L                   A+     C +H +P  +YC+
Sbjct: 83  EPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQ 142

Query: 99  QDRALVCGVCASLGSHRGHRLLP----AAEAHARLKTQLPQQKLQLQEA----CMRKEKS 150
            D   +C VC     HR H +LP      EA   L+++L   K +L++        K++S
Sbjct: 143 DDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKES 202

Query: 151 VAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELG 210
             +L+    E E+        VG +   +R FL   EG L    E +  E        L 
Sbjct: 203 KELLKQMAAEQEK--------VGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLA 254

Query: 211 SLNSYLEQLRQMEKVLEEVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISD 270
            L   + QL ++   ++E A KP  +FL ++    SR   +    P     +++  + + 
Sbjct: 255 QLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNV 314

Query: 271 DFKFQVWRKMFRALMPALE---------ELTFDPSSAHPSLVVSSSGRRVECSEQKAPPA 321
             K  V + M +     L          ELT DP +A+P L++S   + V   E +A   
Sbjct: 315 SLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGE-RAQDL 373

Query: 322 GEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLW 381
              P +FD    V+A    S G H+WEV+VG K  WA GV      R+G     P +G+W
Sbjct: 374 PNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVW 433

Query: 382 LLGLREGKILEAHVEAKEPRALRSPERRP------TRIGLYLSFGDGVLSFYDASDADAL 435
            L L  G+            A+ SPER P      +R+ + L    G +SFY   D   +
Sbjct: 434 ALQLNGGQYW----------AVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVED---M 480

Query: 436 VPLFAFHERLPRPVYPFFDVC 456
             L+ F       V+P F VC
Sbjct: 481 RHLYTFRVNFQERVFPLFSVC 501


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score =  196 bits (498), Expect = 4e-50
 Identities = 124/472 (26%), Positives = 223/472 (47%), Gaps = 20/472 (4%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67
           L  EL C +CL ++  PV+  C H FCR C+        A G   CP C+      AL+ 
Sbjct: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAP 64

Query: 68  NLQLARLVEGLAQVPQGH----------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGH 117
           +L+LA +VE  +  P             C+ H D + ++C  DRAL+C  C     H  H
Sbjct: 65  SLKLANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALHEQH 123

Query: 118 RLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLG 177
           ++    +A   L+ +L  Q   LQ++     +++ +L+ QL E + + +  R  +GE   
Sbjct: 124 QVTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFE 183

Query: 178 KMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEE-VADKPQTE 236
           ++   L   + ++  E E         + +++   +  L ++++  ++L+E +A+  +  
Sbjct: 184 RLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHT 243

Query: 237 FLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPS 296
           FL     ++ RL+  + E+      D      +   ++ +W+ +F+ + P    LT DP 
Sbjct: 244 FLAGVASLSERLKGKIHETNLTYE-DFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPG 302

Query: 297 SAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPR 356
           +AH  L++S     V        P  + P++FD  V+V+  +  S G HYWEV V +K +
Sbjct: 303 TAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQ 362

Query: 357 WALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLY 416
           W +G+    A R+G +   PS+G + + + +G    A     EP    +   +  ++G++
Sbjct: 363 WVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSA---CTEPWTRLNVRDKLDKVGVF 419

Query: 417 LSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCW-HDKGKNAQPL 467
           L +  G+L FY+A D   +  L+ F E+ P  +  +F     H  GKN QPL
Sbjct: 420 LDYDQGLLIFYNADD---MSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPL 468


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  191 bits (486), Expect = 1e-48
 Identities = 143/491 (29%), Positives = 230/491 (46%), Gaps = 49/491 (9%)

Query: 7   LLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALS 66
           ++ +E++CP+CL  F  PV+ ECGHSFC+ C+ +V       G  +CP C+     + L 
Sbjct: 9   MMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVG----KGGGSVCPVCRQRFLLKNLR 64

Query: 67  TNLQLARLVEGLAQVPQG--------HCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHR 118
            N QLA +V  L ++ Q          C  H + L ++CE+D   +C VCA    HR H 
Sbjct: 65  PNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKHRDHA 124

Query: 119 LLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQ--FRGAVGEQL 176
           ++P  EA      Q  Q+KLQ+    +R+++ +A    + +EVE  +++  ++  V  Q 
Sbjct: 125 MVPLEEA-----AQEYQEKLQVALGELRRKQELA----EKLEVEIAIKRADWKKTVETQK 175

Query: 177 GKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADK---- 232
            ++       +  L  E +R   E     R +L  L     +L Q  + L+E+  +    
Sbjct: 176 SRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISELDRR 235

Query: 233 ---PQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALE 289
                 E L +  +V  R     +ES     LDI  P +         +KM R       
Sbjct: 236 CHSSALELLQEVIIVLER-----SESWNLKDLDITSPELRSVCHVPGLKKMLRT---CAV 287

Query: 290 ELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEV 349
            +T DP +A+P L++S   R+V   + +    G + R FD    V+  Q    G+HYWEV
Sbjct: 288 HITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEER-FDSYPMVLGAQHFHSGKHYWEV 346

Query: 350 DVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERR 409
           DV  K  W LGV      R+G        G W + L   +  EA    + P  L+ P   
Sbjct: 347 DVTGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVP--- 403

Query: 410 PTRIGLYLSFGDGVLSFYDASDADALVPLFAFHE-RLPRPVYPFFDVCWHDKGKNAQPLL 468
           P ++G++L +  G++SFY+ +D  +L+  ++F E     P+ PFF   ++D GKN  PL 
Sbjct: 404 PCQVGIFLDYEAGMVSFYNITDHGSLI--YSFSECAFTGPLRPFFSPGFNDGGKNTAPLT 461

Query: 469 L----VGPEGA 475
           L    +G +G+
Sbjct: 462 LCPLNIGSQGS 472


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  190 bits (483), Expect = 2e-48
 Identities = 141/477 (29%), Positives = 215/477 (45%), Gaps = 32/477 (6%)

Query: 3   AAPG-LLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVA--GEPAADGTVLCPCCQAP 59
           A PG  L ++  CP+CL     PV+ +CGHSFC  C+       + A  G   CP C+ P
Sbjct: 4   APPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGP 63

Query: 60  TRPQALSTNLQLARLVEGLAQVPQG------HCEEHLDPLSIYCEQDRALVCGVCASLGS 113
            RP     N QLA LVE + ++  G       C  H + LS +CE+D A +C VC +   
Sbjct: 64  FRPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAGPE 123

Query: 114 HRGHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVG 173
           HR HR  P  EA         Q KLQ+    MRKE   A+ +   V  +  +  ++  V 
Sbjct: 124 HRTHRTAPLQEAAGSY-----QVKLQMALELMRKELEDALTQEANVGKKTVI--WKEKVE 176

Query: 174 EQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKP 233
            Q  + R+      G L  E +R         R  L  L     +L Q  K L+E+AD+ 
Sbjct: 177 MQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADEL 236

Query: 234 QTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALE-ELT 292
           Q         +   ++ +L+ S    RL+ +   I  + K        R L+   + ++ 
Sbjct: 237 QERCQRPALGLLEGVRGVLSRSKAVTRLEAEN--IPMELKTACCIPGRRELLRKFQVDVK 294

Query: 293 FDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVG 352
            DP++AHPSL++++  R V+  E        +P +FD    ++  Q  S G HYWEV VG
Sbjct: 295 LDPATAHPSLLLTADLRSVQDGEPWRD-VPNNPERFDTWPCILGLQSFSSGRHYWEVLVG 353

Query: 353 DKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTR 412
           +   W LGV     PR+G     P  G+W L L +G     ++    P         P  
Sbjct: 354 EGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKG---NEYMVLASPSVPLLQLESPRC 410

Query: 413 IGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLL 469
           IG++L +  G +SFY+ +D      ++ F++     + P+F +C      +A PL+L
Sbjct: 411 IGIFLDYEAGEISFYNVTDGSY---IYTFNQLFSGLLRPYFFIC------DATPLIL 458


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  189 bits (480), Expect = 5e-48
 Identities = 144/500 (28%), Positives = 227/500 (45%), Gaps = 44/500 (8%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67
           L QE +CP+CLQ F  P+  +CGH+ C ACL R  G   A+  V CP C+     + +  
Sbjct: 10  LQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWG--TAETNVSCPQCRETFPQRHMRP 67

Query: 68  NLQLARLVEGLAQV----------PQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGH 117
           N  LA + + + Q+            G CE+H +PL +YCE+D+  +C VC     HRGH
Sbjct: 68  NRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDRSREHRGH 127

Query: 118 RLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLG 177
            +LP  EA    K Q+  Q   L+     K++  A  E    E+    +  R  +  +  
Sbjct: 128 SVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFE 187

Query: 178 KMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEF 237
           ++   L   E  L    E +      ++   +   +  +  L  +   LEE   +P  E 
Sbjct: 188 QLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEKQQQPTREL 247

Query: 238 LMKYCLVTSRLQKILAESP--PPARLDIQLPIISDDFKF------QVWRKMFRALMPALE 289
           L       SR ++I    P   P  L  ++ I +    F      Q   KM ++ M  ++
Sbjct: 248 LQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKM-QSDMEKIQ 306

Query: 290 EL----------TFDPSSAHPSLVVSSSGRRVECS--EQKAPPAGEDPRQFDKAVAVVAH 337
           EL          T DP +A+PSL++S + R+V  S  +Q  P   ++P +F+    V+  
Sbjct: 307 ELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLP---DNPERFNLFPCVLGS 363

Query: 338 QQLSEGEHYWEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEA 397
                G HYWEV+VGDK +W +GV      R+G + + P  G W + L  GK   A    
Sbjct: 364 PCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSP 423

Query: 398 KEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAF-HERLPRPVYPFFDVC 456
                LR+P +   R+G++L +  G +SFY+ ++       F F H     PV P+F + 
Sbjct: 424 MTALPLRTPLQ---RVGIFLDYDAGEVSFYNVTER---CHTFTFSHATFCGPVRPYFSLS 477

Query: 457 WHDKGKNAQPLLLVGPEGAE 476
            +  GK+A PL++    G +
Sbjct: 478 -YSGGKSAAPLIICPMSGID 496


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  188 bits (478), Expect = 8e-48
 Identities = 143/498 (28%), Positives = 230/498 (46%), Gaps = 57/498 (11%)

Query: 2   SAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTR 61
           +AA   L  E SC +CL+    PV  ECGH+FC+AC+ R   +   D    CP C+  +R
Sbjct: 17  AAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFP--CPVCRKTSR 74

Query: 62  PQALSTNLQLARLVEGLAQVP--------QGHCEEHLDPLSIYCEQDRALVCGVCASLGS 113
            ++L  N QL  +VE   Q+         +  C +H + LS++C +D+  VC +CA   +
Sbjct: 75  YRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHT 134

Query: 114 HRGHRLLPAAEAHARLKTQLP------QQKLQLQEACMRKEKSVAVLEHQLVEV--EETV 165
           HR H ++P  +A    K +L       +QKLQ    C   E+       +LVE   ++ +
Sbjct: 135 HRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQIL 194

Query: 166 RQFRGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAG-----------VALRRELGSLNS 214
           R+F         + +V L+ LE       +R+R  A            +A   E   L S
Sbjct: 195 REFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQS 254

Query: 215 YLEQLRQMEKVLEEVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKF 274
             E L+ ++  LE+  +K +T   M+   V+  L+K  +  P                ++
Sbjct: 255 GFEMLKDVKSTLEK-CEKVKT---MEVTSVSIELEKNFSNFPR---------------QY 295

Query: 275 QVWRKMFRALMPALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAV 334
              RK+ + L   + ++T DP +AHP+LV+S   + V+  E +     + PR+F     V
Sbjct: 296 FALRKILKQL---IADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCV 352

Query: 335 VAHQQLSEGEHYWEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAH 394
           +A +  + G HYWEV+VGDK  WA+GV      R+G L  +P  G W + L  G    A 
Sbjct: 353 LATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAAT 412

Query: 395 VEAKEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFD 454
                P  ++    +P R+G++L +  G LSFY+ +D      ++ F +     ++P F 
Sbjct: 413 TTPFTPLHIKV---KPKRVGIFLDYEAGTLSFYNVTDRS---HIYTFTDTFTEKLWPLFY 466

Query: 455 VCWHDKGKNAQPLLLVGP 472
                  KNA PL +  P
Sbjct: 467 PGIRAGRKNAAPLTIRPP 484


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  187 bits (475), Expect = 2e-47
 Identities = 142/509 (27%), Positives = 232/509 (45%), Gaps = 49/509 (9%)

Query: 2   SAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTR 61
           +AA   L  E SC +CL+    PV  ECGH+FC+AC+ R   +   D    CP C+  +R
Sbjct: 17  AAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFP--CPVCRKTSR 74

Query: 62  PQALSTNLQLARLVEGLAQVP--------QGHCEEHLDPLSIYCEQDRALVCGVCASLGS 113
            ++L  N QL  +VE   Q+         +  C +H + LS++C +D+  VC +CA   +
Sbjct: 75  YRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLICAISHT 134

Query: 114 HRGHRLLPAAEAHARLKTQLP------QQKLQLQEACMRKEKSVAVLEHQLVEV--EETV 165
           HR H ++P  +A    K +L       +QKLQ    C   E+       +LVE   ++ +
Sbjct: 135 HRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQIL 194

Query: 166 RQFRGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAG-----------VALRRELGSLNS 214
           R+F         + +V L+ LE       +R+R  A            +A   E   L S
Sbjct: 195 REFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQS 254

Query: 215 YLEQLRQMEKVLEEVADKPQTEFLMKYC---------LVT--SRLQKILAESPPPARLDI 263
             E L+ ++  LE+   +     L   C         LV   +R +K+         +++
Sbjct: 255 GFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIEL 314

Query: 264 QLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGE 323
           +    +   ++   RK+ + L   + ++T DP +AHP+LV+S   + V+  E +     +
Sbjct: 315 EKNFSNFPRQYFALRKILKQL---IADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPD 371

Query: 324 DPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLL 383
            PR+F     V+A +  + G HYWEV+VGDK  WA+GV      R+G L  +P  G W +
Sbjct: 372 TPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRV 431

Query: 384 GLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHE 443
            L  G    A      P  ++    +P R+G++L +  G LSFY+ +D      ++ F +
Sbjct: 432 RLWNGDKYAATTTPFTPLHIKV---KPKRVGIFLDYEAGTLSFYNVTDRS---HIYTFTD 485

Query: 444 RLPRPVYPFFDVCWHDKGKNAQPLLLVGP 472
                ++P F        KNA PL +  P
Sbjct: 486 TFTEKLWPLFYPGIRAGRKNAAPLTIRPP 514


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  181 bits (460), Expect = 1e-45
 Identities = 139/478 (29%), Positives = 223/478 (46%), Gaps = 30/478 (6%)

Query: 11  ELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNLQ 70
           EL CPLC   F  P+   CGH+FC AC+       A +    CP C+   +    + N  
Sbjct: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKE--TFCPECKMLCQYNNCTFNPV 95

Query: 71  LARLVEGLAQVP--QGH--CEEHLDPLSIYCEQDRALVCGVC--ASLGSHRGHRLLPAAE 124
           L +LVE + ++P  +GH  C EH + L ++ + D  L+C  C  A L   +    L  ++
Sbjct: 96  LDKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISD 155

Query: 125 AHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLA 184
           A      +L  Q+ QL+      +    + +  +   +E     +  V  +  K+  FL 
Sbjct: 156 AVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLH 215

Query: 185 ALEGSLDCEAERVRGEAGVALRRELG-SLNSYLEQLRQMEKVLEEVADKPQTE----FLM 239
           + E  +  E      E G AL  E+  +L+   EQ    + +L  +  K + +    FL 
Sbjct: 216 SKEKDILTELR----EEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLK 271

Query: 240 KYCLVTSRLQ---KILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPS 296
               +   L+   K+LA     +R  + L       ++ VWR+M   L P L  LT DP 
Sbjct: 272 DITTLLHSLEQGMKVLATRELISR-KLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPK 330

Query: 297 SAHPSLVVSSSGRRVECSE-QKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKP 355
           +AHP+LV+S S   V   + +K  P  +DP +FD +VAV+  +  + G+ YWEV+V  K 
Sbjct: 331 TAHPNLVLSKSQTSVWHGDIKKIMP--DDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKT 388

Query: 356 RWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGL 415
           +W +GV+     R+G     P QG WLL LR    L+A      P    +      ++G+
Sbjct: 389 KWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKA---LDLPSFSLTLTNNLDKVGI 445

Query: 416 YLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPE 473
           YL +  G LSFY+A     +  ++ F       +YP+F  C +D G+N +PL ++ P+
Sbjct: 446 YLDYEGGQLSFYNAK---TMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 500


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  181 bits (458), Expect = 2e-45
 Identities = 134/449 (29%), Positives = 209/449 (46%), Gaps = 40/449 (8%)

Query: 3   AAPGL---LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAP 59
           AAP L   L +E +C +CL  F  PV  +CGH+FCR C+ R  G+P  +G   CP C+  
Sbjct: 2   AAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP--EGPYACPECREL 59

Query: 60  TRPQALSTNLQLARLVEGLAQ------VPQGHCEEHLDPLSIYCEQDRALVCGVCASLGS 113
           +  + L  N  LA++ E   +      VPQG C  H +PL+ +C  +  L+C  C   G 
Sbjct: 60  SPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGE 119

Query: 114 HRGHRLLP----AAEAHARLKTQLPQQKLQLQEACMRKEKS--VAVLEHQLVEVEETVRQ 167
           H  HR+ P    A +  A+L+  L   + Q+Q+A + + ++    VL  ++VE      Q
Sbjct: 120 HWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVE-----SQ 174

Query: 168 FRGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLE 227
            +  +GE   ++R  LA  E  L    E    E    LR     L      L ++   LE
Sbjct: 175 RQNVLGE-FERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELE 233

Query: 228 EVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPA 287
                P    L        R+Q +  +  PP  + ++L  +          + FR     
Sbjct: 234 GRCQLPALGLLQDIKDALRRVQDVKLQ--PPEVVPMELRTVCRVPGLVETLRRFRG---- 287

Query: 288 LEELTFDPSSAHPSLVVSSSGRRVECSE-QKAPPAGEDPRQFDKAVAVVAHQQLSEGEHY 346
             ++T DP +A+P L++S   R V+  + ++A P  + P +FD    V+  ++ + G HY
Sbjct: 288 --DVTLDPDTANPELILSEDRRSVQRGDLRQALP--DSPERFDPGPCVLGQERFTSGRHY 343

Query: 347 WEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSP 406
           WEV+VGD+  WALGV      R+ +       G W+L       L ++  + E RAL   
Sbjct: 344 WEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWIL-----VFLGSYYNSSE-RALAPL 397

Query: 407 ERRPTRIGLYLSFGDGVLSFYDASDADAL 435
              P R+G++L +  G LSFY A+D   L
Sbjct: 398 RDPPRRVGIFLDYEAGHLSFYSATDGSLL 426


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  168 bits (426), Expect = 9e-42
 Identities = 135/466 (28%), Positives = 199/466 (42%), Gaps = 39/466 (8%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACL--------GRVAGEPAADGTVLCPCCQAP 59
           L +E +C +CL  F  PV   CGH+FCRAC+        G+  G     G+  CP C+  
Sbjct: 10  LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGK-KGRRKRKGSFPCPECREM 68

Query: 60  TRPQALSTNLQLARLVEGLAQVP----QGHCEEHLDPLSIYCEQDRALVCGVCASLGSHR 115
           +  + L  N  L ++ E   Q P    Q  C+EH +PL ++C++D++ +C VC     HR
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHR 128

Query: 116 GHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQ 175
            HR+LPA EA    K +L +    L+E   R     A  E  L E +  V++ R  +  +
Sbjct: 129 LHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLE 188

Query: 176 LGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQT 235
             KM ++L   E  L    E    E    LR  +  L+     L  +   LEE + +   
Sbjct: 189 FEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPL 248

Query: 236 EFLMKYCLVTSRLQKILAESP---PPARLDIQLPIISDDFKFQVWRKMFRALMPALEELT 292
           + L       SR   +  + P   PP R      +                L   LE++ 
Sbjct: 249 QMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPG----------QIEVLRGFLEDVV 298

Query: 293 FDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVA---VVAHQQLSEGEHYWEV 349
            D +SA+P L++  S +R       + P G      D+ VA    V     S G HYWEV
Sbjct: 299 PDATSAYPYLLLYESRQRRYLG---SSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEV 355

Query: 350 --DVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPE 407
             ++     WALGV      R+ R+   P  G W++ L +G    +   A  P  L  P 
Sbjct: 356 GMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEP- 414

Query: 408 RRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFF 453
             P+ +G++L F  G +SFY  SD   L          P P+ PFF
Sbjct: 415 --PSHMGIFLDFEAGEVSFYSVSDGSHLHTY--SQATFPGPLQPFF 456


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  168 bits (426), Expect = 9e-42
 Identities = 135/466 (28%), Positives = 199/466 (42%), Gaps = 39/466 (8%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACL--------GRVAGEPAADGTVLCPCCQAP 59
           L +E +C +CL  F  PV   CGH+FCRAC+        G+  G     G+  CP C+  
Sbjct: 10  LQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGK-KGRRKRKGSFPCPECREM 68

Query: 60  TRPQALSTNLQLARLVEGLAQVP----QGHCEEHLDPLSIYCEQDRALVCGVCASLGSHR 115
           +  + L  N  L ++ E   Q P    Q  C+EH +PL ++C++D++ +C VC     HR
Sbjct: 69  SPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHR 128

Query: 116 GHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQ 175
            HR+LPA EA    K +L +    L+E   R     A  E  L E +  V++ R  +  +
Sbjct: 129 LHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLE 188

Query: 176 LGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQT 235
             KM ++L   E  L    E    E    LR  +  L+     L  +   LEE + +   
Sbjct: 189 FEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPL 248

Query: 236 EFLMKYCLVTSRLQKILAESP---PPARLDIQLPIISDDFKFQVWRKMFRALMPALEELT 292
           + L       SR   +  + P   PP R      +                L   LE++ 
Sbjct: 249 QMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPG----------QIEVLRGFLEDVV 298

Query: 293 FDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVA---VVAHQQLSEGEHYWEV 349
            D +SA+P L++  S +R       + P G      D+ VA    V     S G HYWEV
Sbjct: 299 PDATSAYPYLLLYESRQRRYLG---SSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEV 355

Query: 350 --DVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPE 407
             ++     WALGV      R+ R+   P  G W++ L +G    +   A  P  L  P 
Sbjct: 356 GMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEP- 414

Query: 408 RRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFF 453
             P+ +G++L F  G +SFY  SD   L          P P+ PFF
Sbjct: 415 --PSHMGIFLDFEAGEVSFYSVSDGSHLHTY--SQATFPGPLQPFF 456


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  167 bits (423), Expect = 2e-41
 Identities = 126/491 (25%), Positives = 226/491 (46%), Gaps = 41/491 (8%)

Query: 10  QELSCPLCLQLFDAPVTAECGHSFCRACLG---RVAGEPAADGTVLCPCCQAPTRPQALS 66
           +E++CP+C+     P++ +CGHSFC +CL     + GE    G   CP C+AP +P+ L 
Sbjct: 12  EEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYT-CPLCRAPVQPRNLR 70

Query: 67  TNLQLARLVEG--LAQVPQGH------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGHR 118
            N QLA +VE   L ++  G       CE H + L ++C++D  ++C  C+    H  H 
Sbjct: 71  PNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCEACSQSPEHEAHS 130

Query: 119 LLPAAEAHARLKTQLPQQKLQL---QEACMRKE----KSVAVLEHQLVEVEETV----RQ 167
           ++P  +     K +L +    L   QE   + E    K  A  + Q+   ++++     +
Sbjct: 131 VVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQSIVWEFEK 190

Query: 168 FRGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLE 227
           ++  + ++    R   A +  +L    +R   E    L      L    + L +M   L+
Sbjct: 191 YQRLLEKKQPPHRQLGAEVAAAL-ASLQREAAETMQKLELNHSELIQQSQVLWRMIAELK 249

Query: 228 EVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPA 287
           E + +P    L     V +R +    + P P  L+++      D +    R++ +     
Sbjct: 250 ERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKT-----DCRVLGLREILKTYAA- 303

Query: 288 LEELTFDPSSAHPSLVVSSSGRRVECSE--QKAPPAGEDPRQFDKAVAVVAHQQLSEGEH 345
             ++  DP +A+  L+VS   +RV   +  QK P   ++P +F +   V+  Q +S G H
Sbjct: 304 --DVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLP---DNPERFYRYNIVLGSQCISSGRH 358

Query: 346 YWEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRS 405
           YWEV+VGD+  W LGV      R+  ++  P  G W++ LR+G    A  +     +L  
Sbjct: 359 YWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPILSLPV 418

Query: 406 PERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQ 465
           P   P R+G+++ +    +SFY+ +D  + +  F  +   P  + P+F  C+     N  
Sbjct: 419 P---PRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYP-FPGRLLPYFSPCYSIGTNNTA 474

Query: 466 PLLLVGPEGAE 476
           PL +   +G +
Sbjct: 475 PLAICSLDGED 485


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  164 bits (416), Expect = 1e-40
 Identities = 125/481 (25%), Positives = 218/481 (45%), Gaps = 32/481 (6%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67
           L +E SCP+CL+    PVT  CGH+FCR+CL         D T  CP C+     ++   
Sbjct: 10  LQEESSCPICLEYLKDPVTINCGHNFCRSCLS--VSWKDLDDTFPCPVCRFCFPYKSFRR 67

Query: 68  NLQLARLVEGLAQVP-----------QGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRG 116
           N QL  L E   Q+               CE+H   L+++C +D  ++C  C+    H+ 
Sbjct: 68  NPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSFSTKHQK 127

Query: 117 HRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQL 176
           H + P  +A +  +  L      L+    R EK + +   + VE+++ V   R  +  + 
Sbjct: 128 HYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEF 187

Query: 177 GKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTE 236
            ++R+FL   +  +  + +         L   L  L+ Y+  L+ + + +E  + +   E
Sbjct: 188 EQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSNLE 247

Query: 237 FLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPS 296
            L +   +  + Q +      P     +L         Q +  + R + P   ++  D +
Sbjct: 248 LLTQAKSMHHKYQNLKC----PELFSFRLTKYGFSLPPQ-YSGLDRIIKPFQVDVILDLN 302

Query: 297 SAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPR 356
           +AHP L+VS   + V   E+K      DPR+F    AV+  Q+ S G HYWEV+VG+KP+
Sbjct: 303 TAHPQLLVSEDRKAVRY-ERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPK 361

Query: 357 WALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALR-SPERRPTRIGL 415
           W LGV      R  +       G W +    G+ +++   A  P+  +  P  +P++IG+
Sbjct: 362 WILGVCQDCLLRNWQDQPSVLGGFWAI----GRYMKSGYVASGPKTTQLLPVVKPSKIGI 417

Query: 416 YLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPEGA 475
           +L +  G LSFY+ +D      L+ F++     V+P+F       G +++PL +     +
Sbjct: 418 FLDYELGDLSFYNMNDRSI---LYTFNDCFTEAVWPYFYT-----GTDSEPLKICSVSDS 469

Query: 476 E 476
           E
Sbjct: 470 E 470


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  162 bits (409), Expect = 8e-40
 Identities = 130/478 (27%), Positives = 221/478 (46%), Gaps = 51/478 (10%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAAD--GTVLCPCCQAPTRPQAL 65
           L  E++CP+C      PVT +CGH+FCRACL R    P  D   +  CP C+ P RP + 
Sbjct: 10  LADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSF 69

Query: 66  STNLQLARLVEGLAQV---------PQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRG 116
             N QLA +VE + ++          +  C+EH + +  +CE D   +C VC   G H  
Sbjct: 70  RPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHAT 129

Query: 117 HRLLPAAEAHARLKTQ-------LPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFR 169
           H +    +A A  + Q       L +++ ++QE   R+ K + VL  Q+    + V    
Sbjct: 130 HTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISEF 189

Query: 170 GAVGEQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEV 229
             + + L + +  L A   S D +  R R E  + +  E+   ++ +E+       LEE 
Sbjct: 190 AHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEE-------LEEK 242

Query: 230 ADKPQTEFL--MKYCLV---TSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRAL 284
            ++P  E L  ++  L+   T + +K +A SP   +     P        Q   KMF   
Sbjct: 243 NERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFP--QQALPLQREMKMFLEK 300

Query: 285 M-------PALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAH 337
           +       PA   ++ DP ++HP L++S   +R + S  K   + ++P++FD+A  V+AH
Sbjct: 301 LCFELDYEPA--HISLDPQTSHPKLLLSEDHQRAQFS-YKWQNSPDNPQRFDRATCVLAH 357

Query: 338 QQLSEGEHYW--EVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHV 395
             ++ G H W   +D+       +GV++ +  R+G L   P +G+W + L  G +     
Sbjct: 358 TGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLAWGFV---SA 414

Query: 396 EAKEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFF 453
               P  L   E +P ++ + L +  G ++F +A   +   P++ F     R V PFF
Sbjct: 415 LGSFPTRLTLKE-QPRQVRVSLDYEVGWVTFTNAVTRE---PIYTFTASFTRKVIPFF 468


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  157 bits (398), Expect = 2e-38
 Identities = 119/482 (24%), Positives = 213/482 (44%), Gaps = 40/482 (8%)

Query: 1   MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPT 60
           ++AA   L  E  C +CL     PVT ECGH+FCR+C+ +   +        CP C+   
Sbjct: 3   VAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLD--LQELFPCPVCRHQC 60

Query: 61  RPQALSTNLQLARLVEGLAQVPQGH------------CEEHLDPLSIYCEQDRALVCGVC 108
           +     +N QL R++E +A++ Q              CE+H  PLS++C++D  ++C +C
Sbjct: 61  QEGHFRSNTQLGRMIE-IAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLC 119

Query: 109 ASLGSHRGHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQF 168
                H+GH + P  +A    + +       L++     +K ++    + +E+ E V   
Sbjct: 120 TQPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQ 179

Query: 169 RGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEE 228
           R  +  +   +  FL   + ++         +    L   + + ++Y   L+     + E
Sbjct: 180 RQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVVE 239

Query: 229 VADKPQTEFLMKYCLVTSRLQKILAES---PPPARLDIQLPIISDDFKFQVWRKMFRALM 285
           +++  + E L +         KI  ES     P+   I L      F  Q +  + R + 
Sbjct: 240 LSELSELELLSQI--------KIFYESENESSPSIFSIHLKRDGCSFPPQ-YSALQRIIK 290

Query: 286 PALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEH 345
               E+  DP +AHP+L+VS   +RV  +++K    G  P++F     V+       G H
Sbjct: 291 KFKVEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPG-FPKRFTVKPVVLGFPYFHSGRH 349

Query: 346 YWEVDVGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRS 405
           +WE++VGDK  WA+G+     P + R  +   Q  W + L++      H     P  L  
Sbjct: 350 FWEIEVGDKSEWAIGICKDSLPTKARRPSSAQQECWRIELQDDGY---HAPGAFPTPLLL 406

Query: 406 PERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQ 465
            E +   IG++L +  G +SFY+ ++   +     F +    P+ P+F V     G ++Q
Sbjct: 407 -EVKARAIGIFLDYEMGEISFYNMAEKSHIC---TFTDTFTGPLRPYFYV-----GPDSQ 457

Query: 466 PL 467
           PL
Sbjct: 458 PL 459


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  157 bits (396), Expect = 3e-38
 Identities = 118/476 (24%), Positives = 212/476 (44%), Gaps = 36/476 (7%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEP--AADGTVLCPCCQAPTRPQAL 65
           + +E++CP+CL+L   P++ +CGHSFC+AC+     E     +G   CP CQ   +P  L
Sbjct: 9   IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 68

Query: 66  STNLQLARLVEGLAQVPQGH--------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGH 117
             N  LA +V  L +V  G         C +H + L ++C++D  ++C +C     HRGH
Sbjct: 69  RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 128

Query: 118 RLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLG 177
                 E     + +  +   +L+      EK  A +  +    +  +   R  +  +  
Sbjct: 129 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 188

Query: 178 KMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQ--- 234
           ++R  L  +E     E +++  E    LR    + N  + Q + + +++ ++  + Q   
Sbjct: 189 QLRNILDRVE---QRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGST 245

Query: 235 TEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFK--FQVWRKMFRALMPALEELT 292
            E L     VT R +      P      ++    + D K   +V R++   +     ++T
Sbjct: 246 MELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCREL-TDVQSYWVDVT 304

Query: 293 FDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVG 352
            +P +A+ +LV++ + R+V     K        + +D   +V+  Q  S G+HYWEVDV 
Sbjct: 305 LNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYD--CSVLGSQHFSSGKHYWEVDVA 362

Query: 353 DKPRWALGVIA-AEAPRRGRLHAV----------PSQGLWLLGLREGKILEAHVEAKEPR 401
            K  W LGV + +  P     H            P  G W++GL+      A+ E   P 
Sbjct: 363 KKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAY-EDSSPS 421

Query: 402 ALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHE-RLPRPVYPFFDVC 456
            L S    P R+G++L +  G +SFY+ ++     P++ F +   P  + P+F+ C
Sbjct: 422 LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHG--FPIYTFSKYYFPTTLCPYFNPC 475


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  157 bits (396), Expect = 3e-38
 Identities = 118/476 (24%), Positives = 212/476 (44%), Gaps = 36/476 (7%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEP--AADGTVLCPCCQAPTRPQAL 65
           + +E++CP+CL+L   P++ +CGHSFC+AC+     E     +G   CP CQ   +P  L
Sbjct: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPGNL 96

Query: 66  STNLQLARLVEGLAQVPQGH--------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGH 117
             N  LA +V  L +V  G         C +H + L ++C++D  ++C +C     HRGH
Sbjct: 97  RPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRGH 156

Query: 118 RLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLG 177
                 E     + +  +   +L+      EK  A +  +    +  +   R  +  +  
Sbjct: 157 HTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEFN 216

Query: 178 KMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQ--- 234
           ++R  L  +E     E +++  E    LR    + N  + Q + + +++ ++  + Q   
Sbjct: 217 QLRNILDRVE---QRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGST 273

Query: 235 TEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFK--FQVWRKMFRALMPALEELT 292
            E L     VT R +      P      ++    + D K   +V R++   +     ++T
Sbjct: 274 MELLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAPDLKRMLRVCREL-TDVQSYWVDVT 332

Query: 293 FDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVG 352
            +P +A+ +LV++ + R+V     K        + +D   +V+  Q  S G+HYWEVDV 
Sbjct: 333 LNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYD--CSVLGSQHFSSGKHYWEVDVA 390

Query: 353 DKPRWALGVIA-AEAPRRGRLHAV----------PSQGLWLLGLREGKILEAHVEAKEPR 401
            K  W LGV + +  P     H            P  G W++GL+      A+ E   P 
Sbjct: 391 KKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAY-EDSSPS 449

Query: 402 ALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHE-RLPRPVYPFFDVC 456
            L S    P R+G++L +  G +SFY+ ++     P++ F +   P  + P+F+ C
Sbjct: 450 LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHG--FPIYTFSKYYFPTTLCPYFNPC 503


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  151 bits (381), Expect = 1e-36
 Identities = 127/445 (28%), Positives = 188/445 (42%), Gaps = 39/445 (8%)

Query: 29  CGHSFCRACL--------GRVAGEPAADGTVLCPCCQAPTRPQALSTNLQLARLVEGLAQ 80
           CGH+FCRAC+        G+  G     G+  CP C+  +  + L  N  L ++ E   Q
Sbjct: 4   CGHNFCRACIQLSWEKARGK-KGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQ 62

Query: 81  VP----QGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQ 136
            P    Q  C+EH +PL ++C++D++ +C VC     HR HR+LPA EA    K +L + 
Sbjct: 63  HPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEED 122

Query: 137 KLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDCEAER 196
              L+E   R     A  E  L E +  V++ R  +  +  KM ++L   E  L    E 
Sbjct: 123 MEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALET 182

Query: 197 VRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFLMKYCLVTSRLQKILAESP 256
              E    LR  +  L+     L  +   LEE + +   + L       SR   +  + P
Sbjct: 183 EEEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCP 242

Query: 257 ---PPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHPSLVVSSSGRRVEC 313
              PP R      +                L   LE++  D +SA+P L++  S +R   
Sbjct: 243 EVAPPTRPRTVCRVPG----------QIEVLRGFLEDVVPDATSAYPYLLLYESRQRRYL 292

Query: 314 SEQKAPPAGEDPRQFDKAVA---VVAHQQLSEGEHYWEV--DVGDKPRWALGVIAAEAPR 368
               + P G      D+ VA    V     S G HYWEV  ++     WALGV      R
Sbjct: 293 G---SSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSR 349

Query: 369 RGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFGDGVLSFYD 428
           + R+   P  G W++ L +G    +   A  P  L  P   P+ +G++L F  G +SFY 
Sbjct: 350 KDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEP---PSHMGIFLDFEAGEVSFYS 406

Query: 429 ASDADALVPLFAFHERLPRPVYPFF 453
            SD   L          P P+ PFF
Sbjct: 407 VSDGSHLHTY--SQATFPGPLQPFF 429


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  150 bits (378), Expect = 3e-36
 Identities = 125/456 (27%), Positives = 198/456 (43%), Gaps = 56/456 (12%)

Query: 45  PAADGTVLCPCCQAPTRPQALSTNLQLARLVEGLAQV-----------PQGHCEEHLDPL 93
           PA      CP C+     ++   NLQLA +V+ + Q+            QG C +H + L
Sbjct: 175 PAPRRCFTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGICPKHQEAL 234

Query: 94  SIYCEQDRALVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAV 153
            ++CE D   +C VC    SH+ H ++P  E     K +L      L++     +K  A 
Sbjct: 235 KLFCEVDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAK 294

Query: 154 LEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLN 213
            E ++ E++  ++    AV  + G++  FLA  +  L+    R+R      L R   + +
Sbjct: 295 EERRVTELKSQMKSELAAVASEFGRLTRFLAEEQAGLE---RRLREMHEAQLGRAGAAAS 351

Query: 214 SYLEQLRQMEKVLEEVADKPQ---TEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISD 270
              EQ  Q+ ++L E  ++ Q      L       +R +++  + P     D   P   D
Sbjct: 352 RLAEQAAQLSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPDPCQPHSHD 411

Query: 271 DFKFQVWRKMFRALMPALE-ELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFD 329
                + RKM R    A   +LT DP +AHP+L++S   R V  +E++   A + P++F 
Sbjct: 412 FLTDAIVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVA-DHPKRFS 470

Query: 330 KAVAVVAHQQLSEGEHYWEVDVGDKPRWALGVI------------------------AAE 365
               V+  Q    G HYWEV+VG +  WA+G                          +  
Sbjct: 471 ADCCVLGAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRH 530

Query: 366 APRRGRLHAVPSQGL-----WLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFG 420
             RR RLH +P Q L     W +G   GK  +A  ++   + L SP  +P R G+YL + 
Sbjct: 531 HHRRRRLH-LPQQPLLQREVWCVG-TNGKRYQA--QSSTEQTLLSPSEKPRRFGVYLDYE 586

Query: 421 DGVLSFYDASDADALVPLFAFHER-LPRPVYPFFDV 455
            G L FY   +A+ L  +  F    L   V+PFF V
Sbjct: 587 AGRLGFY---NAETLAHVHTFSAAFLGERVFPFFRV 619



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 16/36 (44%), Positives = 23/36 (63%)

Query: 8  LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAG 43
          L +E  C +CL  F  PV+  CGH+FCR C+ ++ G
Sbjct: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLWG 49


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  147 bits (372), Expect = 2e-35
 Identities = 119/457 (26%), Positives = 190/457 (41%), Gaps = 31/457 (6%)

Query: 10  QELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPA----ADGTVLCPCCQAPTRPQAL 65
           +E +C +CL L   PV+  CGHS+C  C+      P+       T  CP C+AP    +L
Sbjct: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSL 71

Query: 66  STNLQLARLVEGLAQVPQG-HCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPAAE 124
             N QL  L+E L +  Q   CEEH +   ++CE +  L+C  C     H+GH      +
Sbjct: 72  RPNKQLGSLIEALKETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHTTALVED 131

Query: 125 AHARLKTQLPQ---QKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRV 181
                K +L +   +  QL++ C  ++ S A+   ++ + +E V+  R  +      ++ 
Sbjct: 132 VCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAM---RITKWKEKVQIQRQKIRSDFKNLQC 188

Query: 182 FLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFLMKY 241
           FL   E S     E+   +    LR     L     +L+     LEE       + L   
Sbjct: 189 FLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLLQNV 248

Query: 242 CLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHPS 301
               SR   +  E+     L++          F V +KM R+   +   +T DP +AH  
Sbjct: 249 NDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDV-KKMLRSHQVS---VTLDPDTAHHE 304

Query: 302 LVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALGV 361
           L++S   R+V     +        R+F     V+  +  + G  Y+EVDVG+   W LGV
Sbjct: 305 LILSEDRRQVTRGYTQ-ENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGV 363

Query: 362 IAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFGD 421
                 R   +   P  G W L L + K    +V    P        +P  +G++L +  
Sbjct: 364 CMENVQRGTGMKQEPQSGFWTLRLCKKK---GYVALTSPPTSLHLHEQPLLVGIFLDYEA 420

Query: 422 GVLSFYD------------ASDADALVPLFAFHERLP 446
           GV+SFY+            AS +D L P F  ++  P
Sbjct: 421 GVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSP 457


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  146 bits (368), Expect = 5e-35
 Identities = 115/475 (24%), Positives = 209/475 (44%), Gaps = 37/475 (7%)

Query: 10  QELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAAD-GTVLCPCCQAPTRPQALSTN 68
           +E++CP+CL+L   P++ +CGHSFC+ACL     +   D G   CP C+   +P+ +  N
Sbjct: 11  EEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIRPN 70

Query: 69  LQLARLVEGLAQV---PQG----HCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLP 121
             +A LVE L +V   P+G    HC  H + L ++C++D  ++C +C     HRGH   P
Sbjct: 71  RHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHHTFP 130

Query: 122 AAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRV 181
             E     + +L      L++     E+  A +  +    +  ++  +  V     ++R 
Sbjct: 131 TEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQLRD 190

Query: 182 FLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQ---TEFL 238
            L   E +   E + +  E    L+    S    ++Q + + +++ ++  + Q    E L
Sbjct: 191 ILDWEESN---ELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELL 247

Query: 239 MKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALE---ELTFDP 295
                V  R + +  + P     + +    + D K  +  ++FR L        ++T  P
Sbjct: 248 QGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGML--EVFRELTDVRRYWVDVTVAP 305

Query: 296 SSAHPSLVVSSSGRRVECSEQKAPPAGEDPR-----QFDKAVAVVAHQQLSEGEHYWEVD 350
           ++     V+S   R+V   + +        R      F+    ++  Q ++ G+HYWEVD
Sbjct: 306 NNI-SCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWEVD 364

Query: 351 VGDKPRWALGVIAAEAPR-----RGRLHAVPSQGLWLLGLREGKILEA------HVEAKE 399
           V  K  W LGV A   P          +  P  G W++GL EG    A      H  +  
Sbjct: 365 VSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHTPSVP 424

Query: 400 PRALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFD 454
                S    P R+G++L +    +SF++ ++   L+  F+ H    +PV+P+ +
Sbjct: 425 FIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFS-HCSFSQPVFPYLN 478


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  144 bits (364), Expect = 1e-34
 Identities = 129/477 (27%), Positives = 189/477 (39%), Gaps = 56/477 (11%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67
           + +EL+CP+CL  F  PV+ ECGH+FCR CL R        G   CP C+ P+ P AL  
Sbjct: 6   IQEELTCPICLDYFQDPVSIECGHNFCRGCLHR--NWAPGGGPFPCPECRHPSAPAALRP 63

Query: 68  NLQLARLVE-----GLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPA 122
           N  LARL E      L  VP G C  H +PL ++CE D+  VC VC     H+ H + P 
Sbjct: 64  NWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123

Query: 123 AEAHARLKTQLPQQKLQLQEACMRKEKSVAVLE----HQLVEVEETVRQFRGAVGEQLGK 178
            EA    + +L    L+ Q   + K K V  L+        + ++ ++  R  +  +  K
Sbjct: 124 DEAFESYREKL----LKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSK 179

Query: 179 MRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQTEFL 238
           +  FL   E        +   E    L      LN  +  L+++   + E +  P  E L
Sbjct: 180 LHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELL 239

Query: 239 M--KYCLVTSRLQKI-LAESPPPARLDIQLPIISDDFK-FQVWRKMFRALMPALEELTFD 294
              K  L  S +Q +  +      +   Q+P++ +  K FQV              +   
Sbjct: 240 QNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQV-------------AVNLA 286

Query: 295 PSSAHPSLVVSSSGRRVECSEQ-----------------KAPPAGEDPRQFDKAVAVVAH 337
             +AHP LV S  GR V+ +                   + P       +F     V+  
Sbjct: 287 EDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGK 346

Query: 338 QQLSEGEHYWEVDVGDKPRWALGVIAAEAPR-RGRLHAVPSQGLWLLGLREGKILEAHVE 396
              + G+HYWEV+  D    A+GV   +      R    P  G+W +             
Sbjct: 347 NVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPL--- 403

Query: 397 AKEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFF 453
              P      E    R+G+YL  G G +SFY A D    V L  F       + PFF
Sbjct: 404 IGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDG---VHLHTFSCSSVSRLRPFF 457


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  143 bits (361), Expect = 3e-34
 Identities = 128/482 (26%), Positives = 214/482 (44%), Gaps = 50/482 (10%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67
           L +EL+C +CL  F +PVT ECGHSFC  CL R   E   +  + CP C          +
Sbjct: 10  LREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEH--NTPLSCPECWRTLEGPHFQS 67

Query: 68  NLQLARLVEGLAQV---------PQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHR 118
           N +L RL     Q+          QG             + ++     V  S G++R H 
Sbjct: 68  NERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQSHGANRVH- 126

Query: 119 LLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEV---EETVRQFRGAVGEQ 175
           L   AE H R K Q     L++     R++++ AVL H+   V   +E  +  +  V  +
Sbjct: 127 LSSEAEEHHREKLQEILNLLRV-----RRKEAQAVLTHEKERVKLCQEETKTCKQVVVSE 181

Query: 176 LGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADKPQT 235
             KM  FL   E     + + +  E    +R+   +     +Q+R + K++ ++    Q+
Sbjct: 182 YMKMHQFLKEEE---QLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQS 238

Query: 236 ---EFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELT 292
              E L +      R + +L + P     ++ L  I+          M   L     E+T
Sbjct: 239 SAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITG---------MKEMLRKFSTEIT 289

Query: 293 FDPSSAHPSLVVSSSGRRVEC--SEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVD 350
            DP++A+  LV+S   + V+   S Q+ P   ++P +FD++  V+  Q  + G HYWEV+
Sbjct: 290 LDPATANAYLVLSEDLKSVKYGGSRQQLP---DNPERFDQSATVLGTQIFTSGRHYWEVE 346

Query: 351 VGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAK-EPRALRSPERR 409
           VG+K  W +G+      R+G L   P     L+GL+ G      V +  + + +R P   
Sbjct: 347 VGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREP--- 403

Query: 410 PTRIGLYLSFGDGVLSFYDASDADAL--VPLFAFHERLPRPVYPFFDVCWHDKGKNAQPL 467
             ++G++L +  G ++FY+ +D   +   P  +F E L     P F  C  ++G N  PL
Sbjct: 404 VCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEAL----RPIFSPCLPNEGTNTDPL 459

Query: 468 LL 469
            +
Sbjct: 460 TI 461


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  139 bits (349), Expect = 7e-33
 Identities = 131/499 (26%), Positives = 197/499 (39%), Gaps = 74/499 (14%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALST 67
           + +EL+CP+CL  F  PV+ ECGH+FCR CL R        G   CP C+ P+ P AL  
Sbjct: 6   IQEELTCPICLDYFQDPVSIECGHNFCRGCLHR--NWAPGGGPFPCPECRHPSAPAALRP 63

Query: 68  NLQLARLVE-----GLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPA 122
           N  LARL E      L  VP G C  H +PL ++CE D+  VC VC     H+ H + P 
Sbjct: 64  NWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHAMAPI 123

Query: 123 AEAHARLKT-----QLPQQKLQL----------QEACMRKEKSVA-----VLEHQLVEV- 161
            EA    +T      + + K +L          +E  ++ ++++      V+  Q VEV 
Sbjct: 124 DEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQDVEVK 183

Query: 162 -----EETVRQFRGAVGEQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYL 216
                ++ ++  R  +  +  K+  FL   E        +   E    L      LN  +
Sbjct: 184 NATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTI 243

Query: 217 EQLRQMEKVLEEVADKPQTEFLM--KYCLVTSRLQKI-LAESPPPARLDIQLPIISDDFK 273
             L+++   + E +  P  E L   K  L  S +Q +  +      +   Q+P++ +  K
Sbjct: 244 ASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLK 303

Query: 274 -FQVWRKMFRALMPALEELTFDPSSAHPSLVVSSSGRRVECSEQ---------------- 316
            FQV              +     +AHP LV S  GR V+ +                  
Sbjct: 304 RFQV-------------AVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAG 350

Query: 317 -KAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWALGVIAAEAPR-RGRLHA 374
            + P       +F     V+     + G+HYWEV+  D    A+GV   +      R   
Sbjct: 351 WRNPQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKM 410

Query: 375 VPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFGDGVLSFYDASDADA 434
            P  G+W +                P      E    R+G+YL  G G +SFY A D   
Sbjct: 411 SPDVGIWAIYWSAAGYWPL---IGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDG-- 465

Query: 435 LVPLFAFHERLPRPVYPFF 453
            V L  F       + PFF
Sbjct: 466 -VHLHTFSCSSVSRLRPFF 483


>gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]
          Length = 493

 Score =  135 bits (339), Expect = 1e-31
 Identities = 128/473 (27%), Positives = 200/473 (42%), Gaps = 54/473 (11%)

Query: 10  QELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNL 69
           +EL C +C   F   VT  CGH+FCR C+ R   E     T  CP C+    P  L TN 
Sbjct: 17  EELLCAVCYDPFRDAVTLRCGHNFCRGCVSR-CWEVQVSPT--CPVCKDRASPADLRTNH 73

Query: 70  QLARLVEG-LAQVPQGH----------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGHR 118
            L  LVE  L +  +G           C  H   LS++C +D+ L+C  C +   H+GHR
Sbjct: 74  TLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHR 133

Query: 119 LLPAAEAHARLKTQLPQQKLQLQEA-----CMRKEKSVAVLEHQLVEVEETVRQFRGAVG 173
           + P  +     + +    +  L+E       MR+    A+ +H  VE         G + 
Sbjct: 134 VQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYE-AIAKHNQVE----AAWLEGRIR 188

Query: 174 EQLGKMRVFLAALEGS-LDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEVADK 232
           ++  K+R FL   E + LD  AE  R +  +A   ++  L    E L    + L+    +
Sbjct: 189 QEFDKLREFLRVEEQAILDAMAEETRQKQLLA-DEKMKQLTEETEVLAHEIERLQMEMKE 247

Query: 233 PQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELT 292
               FLMK+     RL   +   P    + I +       +++VW+KM  ++       +
Sbjct: 248 DDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESV--PFS 305

Query: 293 FDPSSAHPSLVVS-------SSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEH 345
           FDP++A   L VS       + G RV+          E+P +F  A  ++  +  S+G H
Sbjct: 306 FDPNTAAGWLSVSDDLTSVTNHGYRVQV---------ENPERFSSAPCLLGSRVFSQGSH 356

Query: 346 YWEVDVGDKPRWALGVIAA--EAPRRGRLHAV---PSQGLWLLGLREGKILEAHVEAKEP 400
            WEV +G    W +GV+    ++   G  H+       G W +   +G +   H    +P
Sbjct: 357 AWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQG-VEGDHCVTSDP 415

Query: 401 RALRSPERRPTRIGLYLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFF 453
                    P R+ + L   +G LSFY   DA+    L+ FH R    V P+F
Sbjct: 416 ATSPLVLAIPRRLRVELECEEGELSFY---DAERHCHLYTFHARFGE-VRPYF 464


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  134 bits (337), Expect = 2e-31
 Identities = 128/498 (25%), Positives = 210/498 (42%), Gaps = 74/498 (14%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPA--ADGTVLCPCCQAPTRPQAL 65
           + +E++CP+CL+L   P++ +CGHSFC+AC+     E    + G   CP CQ   +P  L
Sbjct: 9   IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNL 68

Query: 66  STNLQLARLVEGLAQVPQGH--------CEEHLDPLSIYCEQDRALVCGVCASLGSHRGH 117
             N  LA +VE + +V            CE H   L I+C++D  ++C VC     H+GH
Sbjct: 69  RPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGH 128

Query: 118 RLLPAAEAHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGE--Q 175
           +     E          Q+KLQ+    + KE      + +  ++E+ +RQ R A     Q
Sbjct: 129 QTFRINEVVKEC-----QEKLQVALQRLIKE------DQEAEKLEDDIRQERTAWKNYIQ 177

Query: 176 LGKMRVFLAALEGSLDCEAERVRG-----EAGVALRRELGSLNSYLEQLRQMEKVLEEVA 230
           + + ++     E  +  + E  R      E  V +   L +    L Q RQ    L    
Sbjct: 178 IERQKILKGFNEMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDL 237

Query: 231 DK----PQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMP 286
            +       E L     V  R +    + P      ++      D            ++ 
Sbjct: 238 QRRLRGSSVEMLQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLS---------GMLQ 288

Query: 287 ALEELT----------FDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVA 336
            L+ELT           +P SA  ++ +S   R+V+ + +       +P  F  A  V  
Sbjct: 289 VLKELTDVQYYWVDVMLNPGSATSNVAISVDQRQVK-TVRTCTFKNSNPCDFS-AFGVFG 346

Query: 337 HQQLSEGEHYWEVDVGDKPRWALGV---IAAEAPRRGRLHAV--------------PSQG 379
            Q  S G++YWEVDV  K  W LGV   I++   R+    A               P  G
Sbjct: 347 CQYFSSGKYYWEVDVSGKIAWILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYG 406

Query: 380 LWLLGLREGKILEAHVE--AKEPRALR-SPERRPTRIGLYLSFGDGVLSFYDASDADALV 436
            W++GL+      A  +  + +P+ L       P RIG++L +  G++SF++ ++  AL+
Sbjct: 407 YWVIGLQNTCEYNAFEDSSSSDPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALI 466

Query: 437 PLFAFHERLPRPVYPFFD 454
             F+   R  RP YP+F+
Sbjct: 467 YKFS-GCRFSRPAYPYFN 483


>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
           sapiens]
          Length = 395

 Score =  134 bits (337), Expect = 2e-31
 Identities = 104/370 (28%), Positives = 173/370 (46%), Gaps = 42/370 (11%)

Query: 8   LHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAAD--GTVLCPCCQAPTRPQAL 65
           L  E++CP+C      PVT +CGH+FCRACL R    P  D   +  CP C+ P RP + 
Sbjct: 10  LADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGSF 69

Query: 66  STNLQLARLVEGLAQV---------PQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRG 116
             N QLA +VE + ++          +  C+EH + +  +CE D   +C VC   G H  
Sbjct: 70  RPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVVCREAGEHAT 129

Query: 117 HRLLPAAEAHARLKTQ-------LPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFR 169
           H +    +A A  + Q       L +++ ++QE   R+ K + VL  Q+    + V    
Sbjct: 130 HTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVSTKRQQVISEF 189

Query: 170 GAVGEQLGKMRVFLAALEGSLDCEAERVRGEAGVALRRELGSLNSYLEQLRQMEKVLEEV 229
             + + L + +  L A   S D +  R R E  + +  E+   ++ +E+       LEE 
Sbjct: 190 AHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEE-------LEEK 242

Query: 230 ADKPQTEFL--MKYCLV---TSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKMFRAL 284
            ++P  E L  ++  L+   T + +K +A SP   +     P        Q   KMF   
Sbjct: 243 NERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFP--QQALPLQREMKMFLEK 300

Query: 285 M-------PALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAH 337
           +       PA   ++ DP ++HP L++S   +R + S  K   + ++P++FD+A  V+AH
Sbjct: 301 LCFELDYEPA--HISLDPQTSHPKLLLSEDHQRAQFS-YKWQNSPDNPQRFDRATCVLAH 357

Query: 338 QQLSEGEHYW 347
             ++ G H W
Sbjct: 358 TGITGGRHTW 367


>gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]
          Length = 341

 Score =  130 bits (327), Expect = 3e-30
 Identities = 100/354 (28%), Positives = 166/354 (46%), Gaps = 22/354 (6%)

Query: 129 LKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEG 188
           ++ +L  Q+ QL+      +    + +  +   +E     +  V  +  K+  FL + E 
Sbjct: 1   MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK 60

Query: 189 SLDCEAERVRGEAGVALRRELG-SLNSYLEQLRQMEKVLEEVADKPQTE----FLMKYCL 243
            +  E      E G AL  E+  +L+   EQ    + +L  +  K + +    FL     
Sbjct: 61  DILTELR----EEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITT 116

Query: 244 VTSRLQ---KILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPSSAHP 300
           +   L+   K+LA     +R  + L       ++ VWR+M   L P L  LT DP +AHP
Sbjct: 117 LLHSLEQGMKVLATRELISR-KLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHP 175

Query: 301 SLVVSSSGRRVECSE-QKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKPRWAL 359
           +LV+S S   V   + +K  P  +DP +FD +VAV+  +  + G+ YWEV+V  K +W +
Sbjct: 176 NLVLSKSQTSVWHGDIKKIMP--DDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTV 233

Query: 360 GVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSF 419
           GV+     R+G     P QG WLL LR    L+A      P    +      ++G+YL +
Sbjct: 234 GVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKA---LDLPSFSLTLTNNLDKVGIYLDY 290

Query: 420 GDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPE 473
             G LSFY+A     +  ++ F       +YP+F  C +D G+N +PL ++ P+
Sbjct: 291 EGGQLSFYNAK---TMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,161,793
Number of Sequences: 37866
Number of extensions: 970813
Number of successful extensions: 3907
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 176
Number of HSP's that attempted gapping in prelim test: 3033
Number of HSP's gapped (non-prelim): 621
length of query: 477
length of database: 18,247,518
effective HSP length: 106
effective length of query: 371
effective length of database: 14,233,722
effective search space: 5280710862
effective search space used: 5280710862
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.