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Search of human proteins with 56549651
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
(483 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 931 0.0
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 917 0.0
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 682 0.0
gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo s... 300 1e-81
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 108 1e-23
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 106 4e-23
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 105 7e-23
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 103 3e-22
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 87 4e-17
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 86 6e-17
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 86 6e-17
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 86 1e-16
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 85 1e-16
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 82 1e-15
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 77 3e-14
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 76 8e-14
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 76 8e-14
gi|17402900 far upstream element-binding protein [Homo sapiens] 75 2e-13
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 72 1e-12
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 72 1e-12
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 72 1e-12
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 71 2e-12
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 70 3e-12
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 70 3e-12
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 70 3e-12
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 69 7e-12
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 67 5e-11
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 64 2e-10
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 61 2e-09
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 61 2e-09
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 931 bits (2405), Expect = 0.0
Identities = 483/483 (100%), Positives = 483/483 (100%)
Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 180
REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 180
Query: 181 VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN 240
VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN
Sbjct: 181 VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN 240
Query: 241 SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS 300
SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS
Sbjct: 241 SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS 300
Query: 301 YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA 360
YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA
Sbjct: 301 YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA 360
Query: 361 LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL 420
LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL
Sbjct: 361 LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL 420
Query: 421 VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ 480
VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ
Sbjct: 421 VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ 480
Query: 481 KVG 483
KVG
Sbjct: 481 KVG 483
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 917 bits (2370), Expect = 0.0
Identities = 483/507 (95%), Positives = 483/507 (95%), Gaps = 24/507 (4%)
Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQ------------------------VKIIVPN 156
REMPQNVAKTEPVSILQPQTTVNPDRIKQ VKIIVPN
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPN 180
Query: 157 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 216
STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK
Sbjct: 181 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 240
Query: 217 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 276
IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF
Sbjct: 241 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 300
Query: 277 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 336
PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN
Sbjct: 301 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 360
Query: 337 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 396
LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS
Sbjct: 361 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 420
Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA
Sbjct: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
Query: 457 TQAAQYLITQRITYEQGVRAANPQKVG 483
TQAAQYLITQRITYEQGVRAANPQKVG
Sbjct: 481 TQAAQYLITQRITYEQGVRAANPQKVG 507
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 682 bits (1761), Expect = 0.0
Identities = 370/492 (75%), Positives = 409/492 (83%), Gaps = 32/492 (6%)
Query: 21 DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
+ PDSRKRPLE PPE TKR+NTGE+G+YFLKVLIPSYAAGSIIGKGGQTIVQLQKETG
Sbjct: 4 EAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 63
Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
ATIKLSKSKDFYPGTTERVCL+QGT EALNAVH FIAEK+RE+PQ + K E V+ILQPQT
Sbjct: 64 ATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQT 123
Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 200
T+NPDR KQ K+IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP+GINLQERVVTVS
Sbjct: 124 TMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVS 183
Query: 201 GEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLP---- 256
GEPEQ KAV I+QK+QEDPQS SCLNISYANV GPVANSNPTGSPYA+ A+VLP
Sbjct: 184 GEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAA 243
Query: 257 -TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQA 315
+AAAA+GLLG A LAGV AFPA L F+G DL+AI++ALNTLASYGYN N+LGLGL+ A
Sbjct: 244 ASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSA 303
Query: 316 AATGALAAAAASANP-AAAAANLLATYASEASASGSTAGGTA-----GTFALGSLAAATA 369
AA+G LAA AA ANP AAAAANLLA+YA EA A AGG A ALGS A A A
Sbjct: 304 AASGVLAAVAAGANPAAAAAANLLASYAGEAGA--GPAGGAAPPPPPPPGALGSFALA-A 360
Query: 370 ATNGYFGAAS---------PLAASA--------ILGTEK-STDGSKDVVEIAVPENLVGA 411
A NGY GA + PL A+A L EK + + +K++VEIAVPENLVGA
Sbjct: 361 AANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGA 420
Query: 412 ILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 471
ILGKGGKTLVEYQELTGARIQISKKGEF+PGTRNR+VTITG+PAATQAAQYLI+QR+TYE
Sbjct: 421 ILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE 480
Query: 472 QGVRAANPQKVG 483
QGVRA+NPQKVG
Sbjct: 481 QGVRASNPQKVG 492
>gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo
sapiens]
Length = 181
Score = 300 bits (769), Expect = 1e-81
Identities = 151/158 (95%), Positives = 152/158 (96%)
Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNST 158
REMPQNVAKTEPVSILQPQTTVNPDRIKQ P +T
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTT 158
Score = 65.1 bits (157), Expect = 1e-10
Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 3/92 (3%)
Query: 380 PLAASAILGTEKSTDGSKD---VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 436
PL A G+ K T+ +D +++ +P G+I+GKGG+T+V+ Q+ TGA I++SK
Sbjct: 29 PLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKS 88
Query: 437 GEFVPGTRNRKVTITGTPAATQAAQYLITQRI 468
+F PGT R I GT A A I ++I
Sbjct: 89 KDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
Score = 50.8 bits (120), Expect = 3e-06
Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Query: 139 QTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVV 197
+T D +K+++P+ AG IIGKGG T+ + +++GA ++LS+ D ERV
Sbjct: 41 RTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVC 100
Query: 198 TVSGEPEQNRKAVELIIQKIQEDPQS 223
+ G E I +KI+E PQ+
Sbjct: 101 LIQGTVEALNAVHGFIAEKIREMPQN 126
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 108 bits (270), Expect = 1e-23
Identities = 109/424 (25%), Positives = 185/424 (43%), Gaps = 85/424 (20%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNI 229
+ E +GA VQ++ P N ER +T++G P+ + V+ I + E P G + I
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG--VTI 176
Query: 230 SYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLV 289
Y P+ SP A G ++ + A+FP
Sbjct: 177 PY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP------------ 206
Query: 290 AITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASG 349
+T S N + G L G A P + LA S
Sbjct: 207 ------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHFPM-- 254
Query: 350 STAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLV 409
T G + +++ GY+G L ASA + E+ +P +L+
Sbjct: 255 -----THGNTGFSGIESSSPEVKGYWG----LDASAQTTSH----------ELTIPNDLI 295
Query: 410 GAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRIT 469
G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI R++
Sbjct: 296 GCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLINVRLS 352
Query: 470 YEQG 473
E G
Sbjct: 353 SETG 356
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 106 bits (265), Expect = 4e-23
Identities = 108/424 (25%), Positives = 184/424 (43%), Gaps = 84/424 (19%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNI 229
+ E +GA VQ++ P N ER +T++G P+ + V+ I + E P G + I
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG--VTI 176
Query: 230 SYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLV 289
Y P+ SP A G ++ + A+FP
Sbjct: 177 PY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP------------ 206
Query: 290 AITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASG 349
+T S N + G L G A P + LA S
Sbjct: 207 ------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHFPM-- 254
Query: 350 STAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLV 409
T G + +++ GY+ L ASA + E+ +P +L+
Sbjct: 255 -----THGNTGFSGIESSSPEVKGYWAG---LDASAQTTSH----------ELTIPNDLI 296
Query: 410 GAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRIT 469
G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI R++
Sbjct: 297 GCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLINVRLS 353
Query: 470 YEQG 473
E G
Sbjct: 354 SETG 357
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 105 bits (263), Expect = 7e-23
Identities = 107/428 (25%), Positives = 188/428 (43%), Gaps = 89/428 (20%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSGS 225
+ E +GA VQ++ P N ER +T++G P+ + V+ ++++ + + P G
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG- 177
Query: 226 CLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTG 285
+ I Y P+ SP A G ++ + A+FP
Sbjct: 178 -VTIPY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP-------- 210
Query: 286 NDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEA 345
+T S N + G L G A P + LA S
Sbjct: 211 ----------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHF 256
Query: 346 SASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVP 405
T G + +++ GY+G L ASA + E+ +P
Sbjct: 257 PM-------THGNTGFSGIESSSPEVKGYWG----LDASAQTTSH----------ELTIP 295
Query: 406 ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLIT 465
+L+G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI
Sbjct: 296 NDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLIN 352
Query: 466 QRITYEQG 473
R++ E G
Sbjct: 353 VRLSSETG 360
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 103 bits (258), Expect = 3e-22
Identities = 106/428 (24%), Positives = 187/428 (43%), Gaps = 88/428 (20%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSGS 225
+ E +GA VQ++ P N ER +T++G P+ + V+ ++++ + + P G
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG- 177
Query: 226 CLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTG 285
+ I Y P+ SP A G ++ + A+FP
Sbjct: 178 -VTIPY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP-------- 210
Query: 286 NDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEA 345
+T S N + G L G A P + LA S
Sbjct: 211 ----------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHF 256
Query: 346 SASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVP 405
T G + +++ GY+ L ASA + E+ +P
Sbjct: 257 PM-------THGNTGFSGIESSSPEVKGYWAG---LDASAQTTSH----------ELTIP 296
Query: 406 ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLIT 465
+L+G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI
Sbjct: 297 NDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLIN 353
Query: 466 QRITYEQG 473
R++ E G
Sbjct: 354 VRLSSETG 361
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 86.7 bits (213), Expect = 4e-17
Identities = 80/329 (24%), Positives = 143/329 (43%), Gaps = 36/329 (10%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
+ + G+ L T T+A ++ +
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATA---ATNGYFGAASPLAAS 384
P +++ ++ + G A L LA + T+G G ++ L AS
Sbjct: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDAS 237
Query: 385 AILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTR 444
A + E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G+
Sbjct: 238 AQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGST 284
Query: 445 NRKVTITGTPAATQAAQYLITQRITYEQG 473
+R+VTITG+ A+ AQYLI R++ E G
Sbjct: 285 DRQVTITGSAASISLAQYLINVRLSSETG 313
Score = 74.7 bits (182), Expect = 2e-13
Identities = 50/175 (28%), Positives = 90/175 (51%), Gaps = 19/175 (10%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
+ E +GA VQ++ P N ER +T++G P+ + V+ I + E P G
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG 173
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 298
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 86.3 bits (212), Expect = 6e-17
Identities = 80/334 (23%), Positives = 142/334 (42%), Gaps = 33/334 (9%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
+ + G+ L T T+A ++ +
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177
Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGAASPL 381
P +++ ++ + G A L LA T G+ G S
Sbjct: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIES-- 235
Query: 382 AASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEF 439
++ + G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+
Sbjct: 236 SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP--- 292
Query: 440 VPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 473
V G+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 293 VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 326
Score = 74.7 bits (182), Expect = 2e-13
Identities = 50/175 (28%), Positives = 90/175 (51%), Gaps = 19/175 (10%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
+ E +GA VQ++ P N ER +T++G P+ + V+ I + E P G
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG 173
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 311
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 86.3 bits (212), Expect = 6e-17
Identities = 86/328 (26%), Positives = 140/328 (42%), Gaps = 43/328 (13%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
+++++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + KA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
+I K +ED + ++NS T P V+P A+ L+G
Sbjct: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVP-ASQCGSLIGKGG 149
Query: 270 LA------GVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAA 323
A V N + T + + + + + +A +
Sbjct: 150 SKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYT---IQG 206
Query: 324 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAA 383
A +P + LA + G T G L ++ A N G +S L A
Sbjct: 207 QYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL--PLHSSEEAQN-LMGQSSGLDA 263
Query: 384 SAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT 443
S T E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+
Sbjct: 264 SPPASTH----------ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GS 310
Query: 444 RNRKVTITGTPAATQAAQYLITQRITYE 471
R++TITGTPA AQYLI R+T E
Sbjct: 311 SERQITITGTPANISLAQYLINARLTSE 338
Score = 80.1 bits (196), Expect = 4e-15
Identities = 57/185 (30%), Positives = 91/185 (49%), Gaps = 22/185 (11%)
Query: 34 PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
P+ G + E G +++L+ GSIIGK G+T+ ++++E+GA I +S+
Sbjct: 27 PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85
Query: 91 FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150
ER+ I G +A+ IA K E N P + P T +
Sbjct: 86 ----CPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------L 132
Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRK 208
+++VP S G +IGKGG+ +K + E +GA VQ++ P N ER VT+SG P+ +
Sbjct: 133 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQ 189
Query: 209 AVELI 213
V+ I
Sbjct: 190 CVKQI 194
Score = 35.4 bits (80), Expect = 0.12
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83
K PL + EA + ++G D ++ IP+ G IIG+ G I ++++ +GA I
Sbjct: 242 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 301
Query: 84 KLSKSKDFYPGTTERVCLIQGT 105
K++ + + G++ER I GT
Sbjct: 302 KIANATE---GSSERQITITGT 320
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 85.5 bits (210), Expect = 1e-16
Identities = 80/338 (23%), Positives = 146/338 (43%), Gaps = 37/338 (10%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
+II K++ED ++ + NS P V+P A+ L+G
Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117
Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNL----NTLGLGLSQAAATGALAA 323
+ + G+ L T T+A ++ + + + + +
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177
Query: 324 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGA 377
P +++ ++ + G A L LA T G+ G
Sbjct: 178 VTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGI 237
Query: 378 ASPLAASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISK 435
S ++ + G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+
Sbjct: 238 ES--SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 295
Query: 436 KGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 473
V G+ +R+VTITG+ A+ AQYLI R++ E G
Sbjct: 296 P---VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 330
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/179 (26%), Positives = 93/179 (51%), Gaps = 23/179 (12%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
I +K+ E + + T + +P T+ +++VP S G +IGKGG +K
Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121
Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSG 224
+ E +GA VQ++ P N ER +T++G P+ + V+ ++++ + + P G
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177
Score = 32.0 bits (71), Expect = 1.3
Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++
Sbjct: 261 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 315
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 85.1 bits (209), Expect = 1e-16
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 22/199 (11%)
Query: 34 PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
P+ G + E G +++L+ GSIIGK G+T+ ++++E+GA I +S+
Sbjct: 27 PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85
Query: 91 FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150
ER+ I G +A+ IA K E N P + P T +
Sbjct: 86 ----CPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------L 132
Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRK 208
+++VP S G +IGKGG+ +K + E +GA VQ++ P N ER VT+SG P+ +
Sbjct: 133 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQ 189
Query: 209 AVELIIQKIQEDPQSGSCL 227
V+ I + E P G+ +
Sbjct: 190 CVKQICVVMLESPPKGATI 208
Score = 85.1 bits (209), Expect = 1e-16
Identities = 85/337 (25%), Positives = 141/337 (41%), Gaps = 35/337 (10%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
+++++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + KA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 268
+I K +ED + ++NS T P V+P + + + G +
Sbjct: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGS 150
Query: 269 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASA 328
+ + G+ L T T++ + + A
Sbjct: 151 KIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPY 210
Query: 329 NPAAAAANLLATYASEASASGSTAGGTAGTFA-LGSLAAATAA------TNGYF-GAASP 380
P A+ ++ + G A L LA TN F G P
Sbjct: 211 RPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLP 270
Query: 381 LAASA----ILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQIS 434
L +S ++G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+
Sbjct: 271 LHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA 330
Query: 435 KKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 471
E G+ R++TITGTPA AQYLI R+T E
Sbjct: 331 NATE---GSSERQITITGTPANISLAQYLINARLTSE 364
Score = 35.4 bits (80), Expect = 0.12
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83
K PL + EA + ++G D ++ IP+ G IIG+ G I ++++ +GA I
Sbjct: 268 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 327
Query: 84 KLSKSKDFYPGTTERVCLIQGT 105
K++ + + G++ER I GT
Sbjct: 328 KIANATE---GSSERQITITGT 346
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 82.0 bits (201), Expect = 1e-15
Identities = 87/360 (24%), Positives = 147/360 (40%), Gaps = 57/360 (15%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
+++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEG----NCPERIITLTGPTNAIFKA 71
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 268
+II K++E ++ + NS P V+P + + G
Sbjct: 72 FAMIIDKLEE-------------DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGC 118
Query: 269 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYN------------LNTLG------- 309
+ + G+ L T T+A + L TL
Sbjct: 119 KIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRV 178
Query: 310 --LGLSQAAATGALAAAAASANPAAAAANLLATYASEA------SASGSTAGGTAGTFAL 361
+ A+ + A + AA AT+ E S G L
Sbjct: 179 MTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKL 238
Query: 362 GSLA------AATAATNGYFGAASPLAASAILGTEKSTDGSKDVV-EIAVPENLVGAILG 414
+A A G+ G S ++ + G S D S E+ +P NL+G I+G
Sbjct: 239 NQVARQQSHFAMMHGGTGFAGIDS--SSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296
Query: 415 KGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGV 474
+ G + E ++++GA+I+I+ V G+ R+VTITG+ A+ AQYLI R++ E+G+
Sbjct: 297 RQGANINEIRQMSGAQIKIANP---VEGSSGRQVTITGSAASISLAQYLINARLSSEKGM 353
Score = 77.0 bits (188), Expect = 3e-14
Identities = 56/208 (26%), Positives = 106/208 (50%), Gaps = 28/208 (13%)
Query: 42 TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL 101
T +G + +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+
Sbjct: 6 TESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CPERIIT 60
Query: 102 IQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGL 161
+ G A+ I +K+ E N + T + +P T+ +++VP + G
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEE-DINSSMTNSTAASRPPVTL--------RLVVPATQCGS 111
Query: 162 IIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQ 215
+IGKGG +K + E +GA VQ++ P N ER +T++G P+ + V+ ++++
Sbjct: 112 LIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGVPQSVTECVKQICLVMLE 168
Query: 216 KIQEDPQSGSCLNISYANVTGPVANSNP 243
+ + PQ G + I Y P+ S+P
Sbjct: 169 TLSQSPQ-GRVMTIPYQ----PMPASSP 191
Score = 37.7 bits (86), Expect = 0.023
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
++ +PN+ G IIG+ GA + + + SGA ++++ +G + R VT++G A
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS--GRQVTITGSAASISLAQ 340
Query: 211 ELIIQKIQEDPQSG 224
LI ++ + G
Sbjct: 341 YLINARLSSEKGMG 354
Score = 30.0 bits (66), Expect = 4.9
Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 3/68 (4%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
++ IP+ G IIG+ G I ++++ +GA IK++ + G++ R I G+ +++
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVE---GSSGRQVTITGSAASISLA 339
Query: 113 HGFIAEKI 120
I ++
Sbjct: 340 QYLINARL 347
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 77.0 bits (188), Expect = 3e-14
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 13/181 (7%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
LK+L + G +IGK G+ + +++ ETG I +S +D ER ++GTVEA +
Sbjct: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336
Query: 112 VHGFIAEKIREMPQN---VAKTEP--VSILQPQTTVNP-------DRIKQVKIIVPNSTA 159
I +K+RE +N T S L P P + V + +P
Sbjct: 337 AEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAV 396
Query: 160 GLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
G IIGK GA +K + +GA ++++ +G ++ ER+V ++G PE KA I K++E
Sbjct: 397 GAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 455
Query: 220 D 220
+
Sbjct: 456 E 456
Score = 69.3 bits (168), Expect = 7e-12
Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 19/177 (10%)
Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA
Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
G I K++E + P+ V + I VP+STAG +IGKGG
Sbjct: 442 QFKAQGRIFGKLKEE----------NFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGK 487
Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQ 222
TV + + A V + + +E +V + G + ++ + I+Q++++ Q
Sbjct: 488 TVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
Score = 62.4 bits (150), Expect = 9e-10
Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 19/200 (9%)
Query: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T
Sbjct: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224
Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
+ + + + ++ G E+ I T E + I E +++ E + +
Sbjct: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPL----- 277
Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTV 199
KI+ N G +IGK G +K + ++G + +S D I ER +TV
Sbjct: 278 ----------KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327
Query: 200 SGEPEQNRKAVELIIQKIQE 219
G E A I++K++E
Sbjct: 328 KGTVEACASAEIEIMKKLRE 347
Score = 43.9 bits (102), Expect = 3e-04
Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
++I+VP G IIGK G T+K + +Q+ + V + +K + E+ VT+ PE +A
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENS-GAAEKPVTIHATPEGTSEA 254
Query: 210 VELIIQKIQED 220
+I++ +Q++
Sbjct: 255 CRMILEIMQKE 265
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)
Query: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
A I+Q G I + P PD +R + PPEA G K N E+
Sbjct: 405 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 464
Query: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
+ + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G
Sbjct: 465 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 522
Query: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
A KIRE+ Q V + E
Sbjct: 523 FASQTAQ----RKIREIVQQVKQQE 543
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
+ I VP VGAI+GK G T+ + T +R+ I +K G + VTI TP T
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253
Query: 460 AQYLITQ 466
A +I +
Sbjct: 254 ACRMILE 260
Score = 39.7 bits (91), Expect = 0.006
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
+++V + +P VGAI+GK G + + GA I+I+ P R V ITG P A
Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
Query: 457 TQAAQYLITQRITYE 471
AQ I ++ E
Sbjct: 442 QFKAQGRIFGKLKEE 456
Score = 38.9 bits (89), Expect = 0.011
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 6/95 (6%)
Query: 390 EKSTDGSKDVVEIAVP----ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
+K D +K EI + LVG ++GK G+ L + + TG +I IS +
Sbjct: 263 QKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322
Query: 446 RKVTITGTPAATQAAQYLITQRI--TYEQGVRAAN 478
R +T+ GT A +A+ I +++ +E + A N
Sbjct: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
Score = 37.7 bits (86), Expect = 0.023
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 402 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQ 461
I VP + G ++GKGGKT+ E Q LT A + I + + V I G A+Q AQ
Sbjct: 471 IRVPSSTAGRVIGKGGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQ 529
Query: 462 YLITQRITYEQGVRAANPQKV 482
I + + + PQ V
Sbjct: 530 RKIREIVQQVKQQEQKYPQGV 550
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 75.9 bits (185), Expect = 8e-14
Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
+++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G A
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
V +I K+ ED + AN P V+P A+ L+G A
Sbjct: 76 VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121
Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
+ + G+ L T T++ + + A
Sbjct: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181
Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 387
+P+ + +L + + G + G G + ++ A+P S +
Sbjct: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233
Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447
G + T S E VP +L+G ++G+ G + E ++++GA I+I + E G R
Sbjct: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288
Query: 448 VTITGTPAATQAAQYLITQRITYEQGVRAANP 479
VTITG+P + AQYLIT + + P
Sbjct: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320
Score = 70.1 bits (170), Expect = 4e-12
Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 19/178 (10%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ I G+ A+
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
IA K+ E A ++ +P T+ ++++P S G +IGK G +K
Sbjct: 75 AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125
Query: 172 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 227
+ E +GA VQ++ P N ER VTVSG P+ V I I E P G+ +
Sbjct: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
Score = 63.2 bits (152), Expect = 5e-10
Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 63/261 (24%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L+++IP+ GS+IGK G I ++++ TGA ++++ D P +TER + G +A+
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161
Query: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRIKQVK---- 151
I I E P ++ + S+ V P + +++
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 152 ------------------------IIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187
+VPN G +IG+ G+ + + + SGA +++ +
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQA 281
Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG-- 245
+G ER VT++G P A LI +CL + + +G +S P
Sbjct: 282 EGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPADLP 328
Query: 246 SPYANTAEVLPTAAAAAGLLG 266
+P++ LPT A GLLG
Sbjct: 329 APFSPPLTALPT--APPGLLG 347
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 75.9 bits (185), Expect = 8e-14
Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
+++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G A
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
V +I K+ ED + AN P V+P A+ L+G A
Sbjct: 76 VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121
Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
+ + G+ L T T++ + + A
Sbjct: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181
Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 387
+P+ + +L + + G + G G + ++ A+P S +
Sbjct: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233
Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447
G + T S E VP +L+G ++G+ G + E ++++GA I+I + E G R
Sbjct: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288
Query: 448 VTITGTPAATQAAQYLITQRITYEQGVRAANP 479
VTITG+P + AQYLIT + + P
Sbjct: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320
Score = 70.1 bits (170), Expect = 4e-12
Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 19/178 (10%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ I G+ A+
Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
IA K+ E A ++ +P T+ ++++P S G +IGK G +K
Sbjct: 75 AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125
Query: 172 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 227
+ E +GA VQ++ P N ER VTVSG P+ V I I E P G+ +
Sbjct: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180
Score = 63.2 bits (152), Expect = 5e-10
Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 63/261 (24%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
L+++IP+ GS+IGK G I ++++ TGA ++++ D P +TER + G +A+
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161
Query: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRIKQVK---- 151
I I E P ++ + S+ V P + +++
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221
Query: 152 ------------------------IIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187
+VPN G +IG+ G+ + + + SGA +++ +
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQA 281
Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG-- 245
+G ER VT++G P A LI +CL + + +G +S P
Sbjct: 282 EGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPADLP 328
Query: 246 SPYANTAEVLPTAAAAAGLLG 266
+P++ LPT A GLLG
Sbjct: 329 APFSPPLTALPT--APPGLLG 347
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 74.7 bits (182), Expect = 2e-13
Identities = 56/211 (26%), Positives = 104/211 (49%), Gaps = 32/211 (15%)
Query: 19 DLDPPDSRKRP-------LEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQT 71
D D PD++K + PP R+ E+ + +P G IIG+GG+
Sbjct: 69 DGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYK------VPDGMVGFIIGRGGEQ 122
Query: 72 IVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGF---IAEKIREMPQNVA 128
I ++Q+E+G I+++ G ER C++ GT E++ + I EK R P
Sbjct: 123 ISRIQQESGCKIQIAPDSG---GLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHH 179
Query: 129 KTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD 188
P + +Q +I++P S AGL+IGKGG T+K + E++G + + Q
Sbjct: 180 GDGPGNAVQ-------------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGP 226
Query: 189 GINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
++ + ++G+P + ++A E++++ I++
Sbjct: 227 QNTGADKPLRITGDPYKVQQAKEMVLELIRD 257
Score = 73.9 bits (180), Expect = 3e-13
Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 18/195 (9%)
Query: 31 EAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
E E GS N G D V IP +A G +IG+ G+ I ++Q + G I+
Sbjct: 263 EVRNEYGSRIGGNEGID------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD- 315
Query: 91 FYPGTT-ERVCLIQGTVEALNAVHGFIAEKIREMPQ-NVAKTEPVSILQPQTTVN----- 143
GTT ER+ I G + I + +R + N P + + N
Sbjct: 316 ---GTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGP 372
Query: 144 PDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGE 202
P +++ IVP GLIIGKGG T+K++ +QSGA ++L + P + ++ T+ G
Sbjct: 373 PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGT 432
Query: 203 PEQNRKAVELIIQKI 217
P+Q A +LI +KI
Sbjct: 433 PQQIDYARQLIEEKI 447
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 3/66 (4%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
E VP+ +VG I+G+GG+ + Q+ +G +IQI+ +P R +TGTP + Q+A
Sbjct: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGTPESVQSA 160
Query: 461 QYLITQ 466
+ L+ Q
Sbjct: 161 KRLLDQ 166
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Query: 399 VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQ 458
V EI +P + G ++GKGG+T+ + QE G ++ + + G G ++ + ITG P Q
Sbjct: 187 VQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA-DKPLRITGDPYKVQ 245
Query: 459 AAQYLITQRITYEQGVR 475
A+ ++ + I + G R
Sbjct: 246 QAKEMVLELIRDQGGFR 262
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/65 (33%), Positives = 34/65 (52%)
Query: 404 VPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYL 463
VP G I+GKGG+T+ + +GARI++ + + TI GTP A+ L
Sbjct: 383 VPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQL 442
Query: 464 ITQRI 468
I ++I
Sbjct: 443 IEEKI 447
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 395 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 454
G + +++ +P VG ++G+ G+ + + Q G RIQ P R ITG P
Sbjct: 273 GGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP---ERIAQITGPP 329
Query: 455 AATQAAQYLITQRITYEQGVRAANP 479
Q A +IT + + V+A NP
Sbjct: 330 DRCQHAAEIITDLL---RSVQAGNP 351
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 71.6 bits (174), Expect = 1e-12
Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%)
Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D
Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152
ERV LI G P V K + IL T V+ ++
Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129
Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212
VP + G IIG+GG T++++ + SGA + ++ +G L R++ +SG ++ A L
Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189
Query: 213 IIQKIQEDPQ 222
I++K+ ED +
Sbjct: 190 ILEKVSEDEE 199
Score = 47.0 bits (110), Expect = 4e-05
Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458
+++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
Query: 459 AAQYLITQRITYEQGVR 475
AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199
T V D I ++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +
Sbjct: 46 TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101
Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234
SG P Q KA I Q + E+ L++ +V
Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136
Score = 32.7 bits (73), Expect = 0.75
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453
G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G
Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
Query: 454 PAATQAAQYLITQRIT 469
P A+ I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 71.6 bits (174), Expect = 1e-12
Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%)
Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D
Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152
ERV LI G P V K + IL T V+ ++
Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129
Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212
VP + G IIG+GG T++++ + SGA + ++ +G L R++ +SG ++ A L
Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189
Query: 213 IIQKIQEDPQ 222
I++K+ ED +
Sbjct: 190 ILEKVSEDEE 199
Score = 47.0 bits (110), Expect = 4e-05
Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458
+++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
Query: 459 AAQYLITQRITYEQGVR 475
AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199
T V D I ++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +
Sbjct: 46 TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101
Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234
SG P Q KA I Q + E+ L++ +V
Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136
Score = 32.7 bits (73), Expect = 0.75
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453
G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G
Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
Query: 454 PAATQAAQYLITQRIT 469
P A+ I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 71.6 bits (174), Expect = 1e-12
Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%)
Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D
Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93
Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152
ERV LI G P V K + IL T V+ ++
Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129
Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212
VP + G IIG+GG T++++ + SGA + ++ +G L R++ +SG ++ A L
Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189
Query: 213 IIQKIQEDPQ 222
I++K+ ED +
Sbjct: 190 ILEKVSEDEE 199
Score = 47.0 bits (110), Expect = 4e-05
Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458
+++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184
Query: 459 AAQYLITQRITYEQGVR 475
AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201
Score = 43.9 bits (102), Expect = 3e-04
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%)
Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199
T V D I ++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ +
Sbjct: 46 TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101
Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234
SG P Q KA I Q + E+ L++ +V
Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136
Score = 32.7 bits (73), Expect = 0.75
Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453
G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G
Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104
Query: 454 PAATQAAQYLITQRIT 469
P A+ I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 71.2 bits (173), Expect = 2e-12
Identities = 62/240 (25%), Positives = 105/240 (43%), Gaps = 20/240 (8%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
++V +P +A G +IG+ G+ I ++Q + G I+ P ER + G +
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
Query: 112 VHGFIAEKI-----REMPQNVAKTEPVSILQPQTTVN-PDRIKQVKIIVPNSTAGLIIGK 165
I+E I R+ +A + +V P ++++ VP GL+IGK
Sbjct: 313 AAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGK 372
Query: 166 GGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
GG +K++ +QSGA V+L + P + R T+ G P+Q A +LI +K+
Sbjct: 373 GGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV------- 425
Query: 225 SCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA---AAAGLLGHANLAGVAAFPAVLS 281
N+ G S P P+ NT + AA + G+ + V+ PA L+
Sbjct: 426 GGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPPAFLT 485
Score = 70.1 bits (170), Expect = 4e-12
Identities = 45/171 (26%), Positives = 88/171 (51%), Gaps = 19/171 (11%)
Query: 56 IPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVH-- 113
+P G IIG+GG+ I ++Q E+G I+++ G ER C++ GT E++
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS---GIPERPCVLTGTPESIEQAKRL 140
Query: 114 -GFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKA 172
G I ++ R P + S +Q +I++P S GL+IG+GG T+K
Sbjct: 141 LGQIVDRCRNGPGFHNDIDSNSTIQ-------------EILIPASKVGLVIGRGGETIKQ 187
Query: 173 VMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQS 223
+ E++G + + Q ++ + ++G+ + ++A E++++ I+E Q+
Sbjct: 188 LQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQA 238
Score = 59.7 bits (143), Expect = 6e-09
Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
++LIP+ G +IG+GG+TI QLQ+ TG + + + P ++ I G +
Sbjct: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL-PTGADKPLRITGDAFKVQQA 224
Query: 113 HGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKA 172
+ E IRE Q + +++ VP G++IG+ G +K
Sbjct: 225 REMVLEIIREKDQADFRGVRGDFNSRMGG------GSIEVSVPRFAVGIVIGRNGEMIKK 278
Query: 173 VMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKI 217
+ +G +Q KPD ER V G P++ + A +I + I
Sbjct: 279 IQNDAGVRIQF--KPDDGISPERAAQVMGPPDRCQHAAHIISELI 321
Score = 47.0 bits (110), Expect = 4e-05
Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
E VP+ +VG I+G+GG+ + Q +G +IQI+ + +P R +TGTP + + A
Sbjct: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIP---ERPCVLTGTPESIEQA 137
Query: 461 QYLITQ 466
+ L+ Q
Sbjct: 138 KRLLGQ 143
Score = 46.2 bits (108), Expect = 7e-05
Identities = 23/81 (28%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447
G D + + EI +P + VG ++G+GG+T+ + QE TG ++ + + G +P ++
Sbjct: 153 GFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP-LPTGADKP 211
Query: 448 VTITGTPAATQAAQYLITQRI 468
+ ITG Q A+ ++ + I
Sbjct: 212 LRITGDAFKVQQAREMVLEII 232
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 120 IREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGA 179
+++ P + + L Q TV + K VP+ G IIG+GG + + +SG
Sbjct: 55 VQKRPLDDGVGNQLGALVHQRTVITEEFK-----VPDKMVGFIIGRGGEQISRIQAESGC 109
Query: 180 WVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQ 215
+Q++ + GI ER ++G PE +A L+ Q
Sbjct: 110 KIQIASESSGI--PERPCVLTGTPESIEQAKRLLGQ 143
Score = 40.0 bits (92), Expect = 0.005
Identities = 18/74 (24%), Positives = 36/74 (48%)
Query: 395 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 454
G + VP + G ++GKGG+ + + +GA +++ + R+ TI G P
Sbjct: 352 GGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVP 411
Query: 455 AATQAAQYLITQRI 468
+ A+ LI +++
Sbjct: 412 QQIEVARQLIDEKV 425
Score = 38.1 bits (87), Expect = 0.018
Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
+E++VP VG ++G+ G+ + + Q G RIQ P R + G P Q
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312
Query: 460 AQYLITQRITYEQ 472
A ++I++ I Q
Sbjct: 313 AAHIISELILTAQ 325
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 70.5 bits (171), Expect = 3e-12
Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137
S ER+ I +E + + I + E +P A +++ V L
Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134
Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195
Q D ++++++ S AG IIG GA +K + E + ++L Q+ P + +R
Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191
Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
VV + G+P++ + +++I+ I E P G
Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
Query: 461 QYLITQRI 468
QYL+ +
Sbjct: 448 QYLLQNSV 455
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + +
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
Query: 113 HGFIAEKIRE 122
+ +++
Sbjct: 448 QYLLQNSVKQ 457
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
Query: 211 ELIIQKIQE 219
L+ +++
Sbjct: 449 YLLQNSVKQ 457
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 70.5 bits (171), Expect = 3e-12
Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137
S ER+ I +E + + I + E +P A +++ V L
Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134
Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195
Q D ++++++ S AG IIG GA +K + E + ++L Q+ P + +R
Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191
Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
VV + G+P++ + +++I+ I E P G
Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220
Score = 52.0 bits (123), Expect = 1e-06
Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
Query: 461 QYLITQRITYEQG 473
QYL+ + G
Sbjct: 448 QYLLQNSVKQYSG 460
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + +
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
Query: 113 HGFIAEKIRE 122
+ +++
Sbjct: 448 QYLLQNSVKQ 457
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
Query: 211 ELIIQKIQE 219
L+ +++
Sbjct: 449 YLLQNSVKQ 457
>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 70.5 bits (171), Expect = 3e-12
Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%)
Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ +
Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79
Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137
S ER+ I +E + + I + E +P A +++ V L
Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134
Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195
Q D ++++++ S AG IIG GA +K + E + ++L Q+ P + +R
Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191
Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
VV + G+P++ + +++I+ I E P G
Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447
Query: 461 QYLITQRI 468
QYL+ +
Sbjct: 448 QYLLQNSV 455
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)
Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
+V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + +
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447
Query: 113 HGFIAEKIRE 122
+ +++
Sbjct: 448 QYLLQNSVKQ 457
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)
Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448
Query: 211 ELIIQKIQE 219
L+ +++
Sbjct: 449 YLLQNSVKQ 457
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 69.3 bits (168), Expect = 7e-12
Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 19/177 (10%)
Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA
Sbjct: 427 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 484
Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
G I K++E + P+ V + I VP+STAG +IGKGG
Sbjct: 485 QFKAQGRIFGKLKEE----------NFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGK 530
Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQ 222
TV + + A V + + +E +V + G + ++ + I+Q++++ Q
Sbjct: 531 TVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587
Score = 63.9 bits (154), Expect = 3e-10
Identities = 104/476 (21%), Positives = 170/476 (35%), Gaps = 62/476 (13%)
Query: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T
Sbjct: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224
Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
+ + + + ++ G E+ I T E + I E +++ E + +
Sbjct: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPL----- 277
Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTV 199
KI+ N G +IGK G +K + ++G + +S D I ER +TV
Sbjct: 278 ----------KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327
Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA 259
G E A I++K++E ++ AN+ P N + G ++ VL A
Sbjct: 328 KGTVEACASAEIEIMKKLREAFENDMLAVNQQANLI-PGLNLSALGI-FSTGLSVLSPPA 385
Query: 260 AAAGLLGHANLAGVAAFPAVLSGFTGNDLVA------------ITSALNTLASYGYNLNT 307
G A S + I + + G +
Sbjct: 386 GPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGK 445
Query: 308 LGLGLSQAAA-TGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAA 366
G + Q A GA A + P + ++ T EA A G +
Sbjct: 446 KGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFK-----------AQGRIFG 494
Query: 367 ATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQEL 426
N +F + A + ST G ++GKGGKT+ E Q L
Sbjct: 495 KLKEEN-FFNPKEEVKLEAHIRVPSSTAG---------------RVIGKGGKTVNELQNL 538
Query: 427 TGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKV 482
T A + I + + V I G A+Q AQ I + + + PQ V
Sbjct: 539 TSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGV 593
Score = 41.2 bits (95), Expect = 0.002
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)
Query: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
A I+Q G I + P PD +R + PPEA G K N E+
Sbjct: 448 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 507
Query: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
+ + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G
Sbjct: 508 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 565
Query: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
A KIRE+ Q V + E
Sbjct: 566 FASQTAQ----RKIREIVQQVKQQE 586
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 66.6 bits (161), Expect = 5e-11
Identities = 62/210 (29%), Positives = 92/210 (43%), Gaps = 21/210 (10%)
Query: 18 IDLDPPDS-RKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQ 76
+ L PP S P PP A + + + + IP+ + G+IIGK GQ I QL
Sbjct: 373 LGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLS 432
Query: 77 KETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSIL 136
+ GA+IK++ ++ P R+ +I G EA G I KI+E V+ E V +
Sbjct: 433 RFAGASIKIAPAEA--PDAKVRMVIITGPPEAQFKAQGRIYGKIKE-ENFVSPKEEVKL- 488
Query: 137 QPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 196
+ I VP+ AG +IGKGG TV + S A V + + + V
Sbjct: 489 ------------EAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVV 536
Query: 197 VTVSGE----PEQNRKAVELIIQKIQEDPQ 222
V ++G RK E++ Q Q Q
Sbjct: 537 VKITGHFYACQVAQRKIQEILTQVKQHQQQ 566
Score = 65.5 bits (158), Expect = 1e-10
Identities = 55/211 (26%), Positives = 100/211 (47%), Gaps = 29/211 (13%)
Query: 21 DPPDSRKRPLEAPP------EAGSTKRTNTGEDGQYF-----LKVLIPSYAAGSIIGKGG 69
D +++ PL+ P + GS+++ + G + L++L+P+ G+IIGK G
Sbjct: 156 DEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEG 215
Query: 70 QTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAK 129
TI + K+T + I + + ++ G E+ I T E +A I E + + Q++
Sbjct: 216 ATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKF 273
Query: 130 TEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD- 188
TE + + KI+ N+ G +IGK G +K + + + + +S +
Sbjct: 274 TEEIPL---------------KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQEL 318
Query: 189 GINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
+ ER +TV G E KA E I++KI+E
Sbjct: 319 TLYNPERTITVKGNVETCAKAEEEIMKKIRE 349
Score = 61.2 bits (147), Expect = 2e-09
Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 36/202 (17%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
LK+L + G +IGK G+ + +++++T I +S ++ ER ++G VE
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
Query: 112 VHGFIAEKIREMPQN-------------------VAKTEPVSILQPQTTVNPDRI----- 147
I +KIRE +N + P S + P T+ P +
Sbjct: 339 AEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYP 398
Query: 148 -------KQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQL--SQKPDGINLQERVVT 198
+ V + +P + G IIGK G +K + +GA +++ ++ PD + R+V
Sbjct: 399 QFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA---KVRMVI 455
Query: 199 VSGEPEQNRKAVELIIQKIQED 220
++G PE KA I KI+E+
Sbjct: 456 ITGPPEAQFKAQGRIYGKIKEE 477
Score = 42.0 bits (97), Expect = 0.001
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 20/138 (14%)
Query: 7 IQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQ 49
I+Q G I + P PD++ R + PPEA G K N E+ +
Sbjct: 428 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK 487
Query: 50 YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTVEA 108
+ +PS+AAG +IGKGG+T+ +LQ + A + + +D P ++V + I G A
Sbjct: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVV--PRDQTPDENDQVVVKITGHFYA 545
Query: 109 LNAVHGFIAEKIREMPQN 126
I E + ++ Q+
Sbjct: 546 CQVAQRKIQEILTQVKQH 563
Score = 40.4 bits (93), Expect = 0.004
Identities = 19/73 (26%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
++++VP G IIGK GAT++ + +Q+ + + + +K + E+ +T+ PE A
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKSITILSTPEGTSAA 256
Query: 210 VELIIQKIQEDPQ 222
+ I++ + ++ Q
Sbjct: 257 CKSILEIMHKEAQ 269
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
+ + VP VGAI+GK G T+ + T ++I + +K G + +TI TP T A
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255
Query: 460 A 460
A
Sbjct: 256 A 256
Score = 39.7 bits (91), Expect = 0.006
Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Query: 398 DVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAAT 457
+ V + +P VGAI+GK G+ + + GA I+I+ P + R V ITG P A
Sbjct: 406 ETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAE--APDAKVRMVIITGPPEAQ 463
Query: 458 QAAQYLITQRITYEQGV 474
AQ I +I E V
Sbjct: 464 FKAQGRIYGKIKEENFV 480
Score = 37.7 bits (86), Expect = 0.023
Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 402 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQAA 460
I VP G ++GKGGKT+ E Q L+ A + + + + P ++ V ITG A Q A
Sbjct: 492 IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPR--DQTPDENDQVVVKITGHFYACQVA 549
Query: 461 QYLITQRIT 469
Q I + +T
Sbjct: 550 QRKIQEILT 558
Score = 37.0 bits (84), Expect = 0.040
Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
++I N VG ++GK G+ L + ++ T +I IS E R +T+ G
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338
Query: 460 AQYLITQRI--TYEQGVRAANPQ 480
A+ I ++I +YE + + N Q
Sbjct: 339 AEEEIMKKIRESYENDIASMNLQ 361
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 64.3 bits (155), Expect = 2e-10
Identities = 47/204 (23%), Positives = 91/204 (44%), Gaps = 21/204 (10%)
Query: 21 DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
D S+ P+ PP T+ +P G IIG+GG+ I ++Q+++G
Sbjct: 128 DSISSQLGPIHPPPRTSMTEEYR------------VPDGMVGLIIGRGGEQINKIQQDSG 175
Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
+++S G ER + G E++ + + + + P
Sbjct: 176 CKVQISPDSG---GLPERSVSLTGAPESVQKAKMMLDDIVSR-----GRGGPPGQFHDNA 227
Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 200
+ Q +I++P AGL+IGKGG T+K + E++G + L Q ++ + +
Sbjct: 228 NGGQNGTVQ-EIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRII 286
Query: 201 GEPEQNRKAVELIIQKIQEDPQSG 224
G+P + ++A E+++ ++E Q G
Sbjct: 287 GDPYKVQQACEMVMDILRERDQGG 310
Score = 58.5 bits (140), Expect = 1e-08
Identities = 43/176 (24%), Positives = 82/176 (46%), Gaps = 13/176 (7%)
Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
+ V +P ++ G +IG+ G+ I ++Q + G I+ + P E++ I G +
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGP---EKIAHIMGPPDRCEH 381
Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQP--------QTTVNPDRIKQVKIIVPNSTAGLII 163
I + ++ + + P Q P ++ +P GL+I
Sbjct: 382 AARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-GEMTFSIPTHKCGLVI 440
Query: 164 GKGGATVKAVMEQSGAWVQLS-QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQ 218
G+GG VKA+ +Q+GA+V++S Q P + ++ + G P+Q A +LI +KI+
Sbjct: 441 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE 496
Score = 47.8 bits (112), Expect = 2e-05
Identities = 23/73 (31%), Positives = 44/73 (60%), Gaps = 3/73 (4%)
Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
E VP+ +VG I+G+GG+ + + Q+ +G ++QIS +P R V++TG P + Q A
Sbjct: 148 EYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLP---ERSVSLTGAPESVQKA 204
Query: 461 QYLITQRITYEQG 473
+ ++ ++ +G
Sbjct: 205 KMMLDDIVSRGRG 217
Score = 35.4 bits (80), Expect = 0.12
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Query: 399 VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQ 458
V EI +P G ++GKGG+T+ + QE G ++ + + G ++ + I G P Q
Sbjct: 235 VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNV-DKPLRIIGDPYKVQ 293
Query: 459 AA 460
A
Sbjct: 294 QA 295
Score = 33.9 bits (76), Expect = 0.34
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 8/85 (9%)
Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQ 458
+++ VP + VG ++G+ G+ + + Q G RIQ + GT K+ I G P +
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQD----DGTGPEKIAHIMGPPDRCE 380
Query: 459 AAQYLITQRITYEQGVRAANPQKVG 483
A +I + Q +R+ P G
Sbjct: 381 HAARIINDLL---QSLRSGPPGPPG 402
Score = 33.5 bits (75), Expect = 0.44
Identities = 21/69 (30%), Positives = 40/69 (57%), Gaps = 6/69 (8%)
Query: 403 AVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVP--GTRNRKV-TITGTPAATQA 459
++P + G ++G+GG+ + + TGA ++IS++ +P G N K+ I G+P
Sbjct: 430 SIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ---LPPNGDPNFKLFIIRGSPQQIDH 486
Query: 460 AQYLITQRI 468
A+ LI ++I
Sbjct: 487 AKQLIEEKI 495
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 19/179 (10%)
Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA
Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 323
Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
G I K++E + P+ V + I VP S AG +IGKGG
Sbjct: 324 QFKAQGRIYGKLKE----------ENFFGPKEEVK----LETHIRVPASAAGRVIGKGGK 369
Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQSG 224
TV + + A V + + + +V + G + ++ + I+ ++++ Q G
Sbjct: 370 TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG 428
Score = 57.0 bits (136), Expect = 4e-08
Identities = 49/213 (23%), Positives = 92/213 (43%), Gaps = 32/213 (15%)
Query: 39 TKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 98
+ R T + + LK+L + G +IGK G+ + +++++T I +S +D ER
Sbjct: 127 SNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPER 186
Query: 99 VCLIQGTVEALNAVHGFIAEKIREMPQN-VAKTEPVSILQP------------------- 138
++G +E I +K+RE +N VA S L P
Sbjct: 187 TITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPP 246
Query: 139 -----------QTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187
+ + + V++ +P G IIGK G +K + + A ++++ P
Sbjct: 247 PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA-PP 305
Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQED 220
+ + + R+V ++G PE KA I K++E+
Sbjct: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338
Score = 40.0 bits (92), Expect = 0.005
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
+++V++ +P VGAI+GK G+ + + A I+I+ P ++ R V ITG P A
Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEA 323
Query: 457 TQAAQYLITQRITYE 471
AQ I ++ E
Sbjct: 324 QFKAQGRIYGKLKEE 338
Score = 37.0 bits (84), Expect = 0.040
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 390 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P +
Sbjct: 337 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 394
Query: 446 RK-VTITGTPAATQAAQ 461
+ V I G A+Q AQ
Sbjct: 395 QVIVKIIGHFYASQMAQ 411
Score = 33.9 bits (76), Expect = 0.34
Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 2/93 (2%)
Query: 390 EKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 449
E++ + ++I N VG ++GK G+ L + ++ T +I IS + R +T
Sbjct: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189
Query: 450 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 480
+ G A+ I +++ YE V A + Q
Sbjct: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 222
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 61.2 bits (147), Expect = 2e-09
Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 19/179 (10%)
Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA
Sbjct: 405 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 462
Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
G I K++E + P+ V + I VP S AG +IGKGG
Sbjct: 463 QFKAQGRIYGKLKE----------ENFFGPKEEVK----LETHIRVPASAAGRVIGKGGK 508
Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQSG 224
TV + + A V + + + +V + G + ++ + I+ ++++ Q G
Sbjct: 509 TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG 567
Score = 60.5 bits (145), Expect = 3e-09
Identities = 61/269 (22%), Positives = 109/269 (40%), Gaps = 46/269 (17%)
Query: 25 SRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 84
SR +P + P A D L++L+P+ G+IIGK G TI + K+T + I
Sbjct: 173 SRGQPRQGSPVAAGAPAKQQQVDIP--LRLLVPTQYVGAIIGKEGATIRNITKQTQSKID 230
Query: 85 LSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP 144
+ + ++ G E+ + T E ++ I E + + ++ + V +
Sbjct: 231 VHRKEN--AGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPL--------- 279
Query: 145 DRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTVSGEP 203
KI+ N+ G +IGK G +K V + + + +S D + ER +TV G
Sbjct: 280 ------KILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAI 333
Query: 204 EQNRKAVELIIQKIQED--------------------------PQSGSCLNISYANVTGP 237
E +A + I++K++E P S S + ++VTG
Sbjct: 334 ENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGA 393
Query: 238 VANSNPTGSPYANTAEVLPTAAAAAGLLG 266
S+ +P +V A A ++G
Sbjct: 394 APYSSFMQAPEQEMVQVFIPAQAVGAIIG 422
Score = 53.9 bits (128), Expect = 3e-07
Identities = 72/329 (21%), Positives = 131/329 (39%), Gaps = 56/329 (17%)
Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
++++VP G IIGK GAT++ + +Q+ + + + +K + E+ ++V PE A
Sbjct: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKAISVHSTPEGCSSA 256
Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
++I++ + ++ + TA+ +P +L H N
Sbjct: 257 CKMILEIMHKEAKD-------------------------TKTADEVPLK-----ILAHNN 286
Query: 270 LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASAN 329
G L G G +L + T + +L L L + T A
Sbjct: 287 FVGR------LIGKEGRNLKKVEQDTETKITIS-SLQDLTLYNPERTITVKGAIENCCRA 339
Query: 330 PAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAAS---PLAASAI 386
+ Y ++ +A + G +LAA G F A+S P S++
Sbjct: 340 EQEIMKKVREAYENDVAAMSLQSHLIPGL----NLAAV-----GLFPASSSAVPPPPSSV 390
Query: 387 LGTEKSTD----GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPG 442
G + +++V++ +P VGAI+GK G+ + + A I+I+ P
Sbjct: 391 TGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPD 448
Query: 443 TRNRKVTITGTPAATQAAQYLITQRITYE 471
++ R V ITG P A AQ I ++ E
Sbjct: 449 SKVRMVIITGPPEAQFKAQGRIYGKLKEE 477
Score = 37.0 bits (84), Expect = 0.040
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 390 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P +
Sbjct: 476 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 533
Query: 446 RK-VTITGTPAATQAAQ 461
+ V I G A+Q AQ
Sbjct: 534 QVIVKIIGHFYASQMAQ 550
Score = 35.4 bits (80), Expect = 0.12
Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 373 GYFGAASPLAASAILGTEKSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARI 431
G+ P S + + D+ + + VP VGAI+GK G T+ + T ++I
Sbjct: 170 GFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKI 229
Query: 432 QISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQ 466
+ +K G + +++ TP +A +I +
Sbjct: 230 DVHRKEN--AGAAEKAISVHSTPEGCSSACKMILE 262
Score = 33.5 bits (75), Expect = 0.44
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 391 KSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 449
K T + +V ++I N VG ++GK G+ L + ++ T +I IS + R +T
Sbjct: 269 KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 328
Query: 450 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 480
+ G A+ I +++ YE V A + Q
Sbjct: 329 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 361
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,631,603
Number of Sequences: 37866
Number of extensions: 790990
Number of successful extensions: 5030
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 3507
Number of HSP's gapped (non-prelim): 982
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.