Guide to the Human Genome
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Search of human proteins with 56549651

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
         (483 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ...   931   0.0  
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ...   917   0.0  
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]         682   0.0  
gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo s...   300   1e-81
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]      108   1e-23
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]       106   4e-23
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]      105   7e-23
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]       103   3e-22
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]       87   4e-17
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]       86   6e-17
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]       86   6e-17
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]       86   1e-16
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]       85   1e-16
gi|222352151 poly(rC) binding protein 1 [Homo sapiens]                 82   1e-15
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ...    77   3e-14
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]        76   8e-14
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]        76   8e-14
gi|17402900 far upstream element-binding protein [Homo sapiens]        75   2e-13
gi|145312259 tudor and KH domain containing isoform a [Homo sapi...    72   1e-12
gi|145312270 tudor and KH domain containing isoform a [Homo sapi...    72   1e-12
gi|145312256 tudor and KH domain containing isoform a [Homo sapi...    72   1e-12
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo...    71   2e-12
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ...    70   3e-12
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ...    70   3e-12
gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ...    70   3e-12
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ...    69   7e-12
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ...    67   5e-11
gi|154355000 KH-type splicing regulatory protein [Homo sapiens]        64   2e-10
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1...    61   2e-09
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ...    61   2e-09

>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
           sapiens]
          Length = 483

 Score =  931 bits (2405), Expect = 0.0
 Identities = 483/483 (100%), Positives = 483/483 (100%)

Query: 1   MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
           MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1   MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60

Query: 61  AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
           AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61  AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120

Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 180
           REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 180

Query: 181 VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN 240
           VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN
Sbjct: 181 VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN 240

Query: 241 SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS 300
           SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS
Sbjct: 241 SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS 300

Query: 301 YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA 360
           YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA
Sbjct: 301 YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA 360

Query: 361 LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL 420
           LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL
Sbjct: 361 LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL 420

Query: 421 VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ 480
           VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ
Sbjct: 421 VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ 480

Query: 481 KVG 483
           KVG
Sbjct: 481 KVG 483


>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
           sapiens]
          Length = 507

 Score =  917 bits (2370), Expect = 0.0
 Identities = 483/507 (95%), Positives = 483/507 (95%), Gaps = 24/507 (4%)

Query: 1   MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
           MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1   MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60

Query: 61  AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
           AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61  AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120

Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQ------------------------VKIIVPN 156
           REMPQNVAKTEPVSILQPQTTVNPDRIKQ                        VKIIVPN
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPN 180

Query: 157 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 216
           STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK
Sbjct: 181 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 240

Query: 217 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 276
           IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF
Sbjct: 241 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 300

Query: 277 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 336
           PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN
Sbjct: 301 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 360

Query: 337 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 396
           LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS
Sbjct: 361 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 420

Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
           KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA
Sbjct: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480

Query: 457 TQAAQYLITQRITYEQGVRAANPQKVG 483
           TQAAQYLITQRITYEQGVRAANPQKVG
Sbjct: 481 TQAAQYLITQRITYEQGVRAANPQKVG 507


>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
          Length = 492

 Score =  682 bits (1761), Expect = 0.0
 Identities = 370/492 (75%), Positives = 409/492 (83%), Gaps = 32/492 (6%)

Query: 21  DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
           + PDSRKRPLE PPE   TKR+NTGE+G+YFLKVLIPSYAAGSIIGKGGQTIVQLQKETG
Sbjct: 4   EAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 63

Query: 81  ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
           ATIKLSKSKDFYPGTTERVCL+QGT EALNAVH FIAEK+RE+PQ + K E V+ILQPQT
Sbjct: 64  ATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQT 123

Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 200
           T+NPDR KQ K+IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP+GINLQERVVTVS
Sbjct: 124 TMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVS 183

Query: 201 GEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLP---- 256
           GEPEQ  KAV  I+QK+QEDPQS SCLNISYANV GPVANSNPTGSPYA+ A+VLP    
Sbjct: 184 GEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAA 243

Query: 257 -TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQA 315
            +AAAA+GLLG A LAGV AFPA L  F+G DL+AI++ALNTLASYGYN N+LGLGL+ A
Sbjct: 244 ASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSA 303

Query: 316 AATGALAAAAASANP-AAAAANLLATYASEASASGSTAGGTA-----GTFALGSLAAATA 369
           AA+G LAA AA ANP AAAAANLLA+YA EA A    AGG A        ALGS A A A
Sbjct: 304 AASGVLAAVAAGANPAAAAAANLLASYAGEAGA--GPAGGAAPPPPPPPGALGSFALA-A 360

Query: 370 ATNGYFGAAS---------PLAASA--------ILGTEK-STDGSKDVVEIAVPENLVGA 411
           A NGY GA +         PL A+A         L  EK + + +K++VEIAVPENLVGA
Sbjct: 361 AANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGA 420

Query: 412 ILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 471
           ILGKGGKTLVEYQELTGARIQISKKGEF+PGTRNR+VTITG+PAATQAAQYLI+QR+TYE
Sbjct: 421 ILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE 480

Query: 472 QGVRAANPQKVG 483
           QGVRA+NPQKVG
Sbjct: 481 QGVRASNPQKVG 492


>gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo
           sapiens]
          Length = 181

 Score =  300 bits (769), Expect = 1e-81
 Identities = 151/158 (95%), Positives = 152/158 (96%)

Query: 1   MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60
           MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA
Sbjct: 1   MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60

Query: 61  AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120
           AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI
Sbjct: 61  AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120

Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNST 158
           REMPQNVAKTEPVSILQPQTTVNPDRIKQ     P +T
Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTT 158



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 3/92 (3%)

Query: 380 PLAASAILGTEKSTDGSKD---VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 436
           PL A    G+ K T+  +D    +++ +P    G+I+GKGG+T+V+ Q+ TGA I++SK 
Sbjct: 29  PLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKS 88

Query: 437 GEFVPGTRNRKVTITGTPAATQAAQYLITQRI 468
            +F PGT  R   I GT  A  A    I ++I
Sbjct: 89  KDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 1/86 (1%)

Query: 139 QTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVV 197
           +T    D    +K+++P+  AG IIGKGG T+  + +++GA ++LS+  D      ERV 
Sbjct: 41  RTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVC 100

Query: 198 TVSGEPEQNRKAVELIIQKIQEDPQS 223
            + G  E        I +KI+E PQ+
Sbjct: 101 LIQGTVEALNAVHGFIAEKIREMPQN 126


>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
          Length = 361

 Score =  108 bits (270), Expect = 1e-23
 Identities = 109/424 (25%), Positives = 185/424 (43%), Gaps = 85/424 (20%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               I +K+ E   + + T   +  +P  T+        +++VP S  G +IGKGG  +K
Sbjct: 71  AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121

Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNI 229
            + E +GA VQ++    P   N  ER +T++G P+   + V+ I   + E P  G  + I
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG--VTI 176

Query: 230 SYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLV 289
            Y           P+ SP             A G   ++  +  A+FP            
Sbjct: 177 PY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP------------ 206

Query: 290 AITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASG 349
                 +T  S   N +  G  L      G  A       P     + LA   S      
Sbjct: 207 ------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHFPM-- 254

Query: 350 STAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLV 409
                T G      + +++    GY+G    L ASA   +           E+ +P +L+
Sbjct: 255 -----THGNTGFSGIESSSPEVKGYWG----LDASAQTTSH----------ELTIPNDLI 295

Query: 410 GAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRIT 469
           G I+G+ G  + E ++++GA+I+I+     V G+ +R+VTITG+ A+   AQYLI  R++
Sbjct: 296 GCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLINVRLS 352

Query: 470 YEQG 473
            E G
Sbjct: 353 SETG 356


>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
          Length = 362

 Score =  106 bits (265), Expect = 4e-23
 Identities = 108/424 (25%), Positives = 184/424 (43%), Gaps = 84/424 (19%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               I +K+ E   + + T   +  +P  T+        +++VP S  G +IGKGG  +K
Sbjct: 71  AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121

Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNI 229
            + E +GA VQ++    P   N  ER +T++G P+   + V+ I   + E P  G  + I
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG--VTI 176

Query: 230 SYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLV 289
            Y           P+ SP             A G   ++  +  A+FP            
Sbjct: 177 PY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP------------ 206

Query: 290 AITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASG 349
                 +T  S   N +  G  L      G  A       P     + LA   S      
Sbjct: 207 ------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHFPM-- 254

Query: 350 STAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLV 409
                T G      + +++    GY+     L ASA   +           E+ +P +L+
Sbjct: 255 -----THGNTGFSGIESSSPEVKGYWAG---LDASAQTTSH----------ELTIPNDLI 296

Query: 410 GAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRIT 469
           G I+G+ G  + E ++++GA+I+I+     V G+ +R+VTITG+ A+   AQYLI  R++
Sbjct: 297 GCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLINVRLS 353

Query: 470 YEQG 473
            E G
Sbjct: 354 SETG 357


>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
          Length = 365

 Score =  105 bits (263), Expect = 7e-23
 Identities = 107/428 (25%), Positives = 188/428 (43%), Gaps = 89/428 (20%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               I +K+ E   + + T   +  +P  T+        +++VP S  G +IGKGG  +K
Sbjct: 71  AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121

Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSGS 225
            + E +GA VQ++    P   N  ER +T++G P+   + V+    ++++ + + P  G 
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG- 177

Query: 226 CLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTG 285
            + I Y           P+ SP             A G   ++  +  A+FP        
Sbjct: 178 -VTIPY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP-------- 210

Query: 286 NDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEA 345
                     +T  S   N +  G  L      G  A       P     + LA   S  
Sbjct: 211 ----------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHF 256

Query: 346 SASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVP 405
                    T G      + +++    GY+G    L ASA   +           E+ +P
Sbjct: 257 PM-------THGNTGFSGIESSSPEVKGYWG----LDASAQTTSH----------ELTIP 295

Query: 406 ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLIT 465
            +L+G I+G+ G  + E ++++GA+I+I+     V G+ +R+VTITG+ A+   AQYLI 
Sbjct: 296 NDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLIN 352

Query: 466 QRITYEQG 473
            R++ E G
Sbjct: 353 VRLSSETG 360


>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
          Length = 366

 Score =  103 bits (258), Expect = 3e-22
 Identities = 106/428 (24%), Positives = 187/428 (43%), Gaps = 88/428 (20%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               I +K+ E   + + T   +  +P  T+        +++VP S  G +IGKGG  +K
Sbjct: 71  AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121

Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSGS 225
            + E +GA VQ++    P   N  ER +T++G P+   + V+    ++++ + + P  G 
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG- 177

Query: 226 CLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTG 285
            + I Y           P+ SP             A G   ++  +  A+FP        
Sbjct: 178 -VTIPY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP-------- 210

Query: 286 NDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEA 345
                     +T  S   N +  G  L      G  A       P     + LA   S  
Sbjct: 211 ----------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHF 256

Query: 346 SASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVP 405
                    T G      + +++    GY+     L ASA   +           E+ +P
Sbjct: 257 PM-------THGNTGFSGIESSSPEVKGYWAG---LDASAQTTSH----------ELTIP 296

Query: 406 ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLIT 465
            +L+G I+G+ G  + E ++++GA+I+I+     V G+ +R+VTITG+ A+   AQYLI 
Sbjct: 297 NDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLIN 353

Query: 466 QRITYEQG 473
            R++ E G
Sbjct: 354 VRLSSETG 361


>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
          Length = 318

 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 80/329 (24%), Positives = 143/329 (43%), Gaps = 36/329 (10%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           +++++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G      KA
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
             +II K++ED             ++  + NS     P      V+P A+    L+G   
Sbjct: 72  FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117

Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
             +  +           G+ L   T    T+A    ++      +               
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177

Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATA---ATNGYFGAASPLAAS 384
             P  +++ ++       +  G  A        L  LA   +    T+G  G ++ L AS
Sbjct: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDAS 237

Query: 385 AILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTR 444
           A   +           E+ +P +L+G I+G+ G  + E ++++GA+I+I+     V G+ 
Sbjct: 238 AQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGST 284

Query: 445 NRKVTITGTPAATQAAQYLITQRITYEQG 473
           +R+VTITG+ A+   AQYLI  R++ E G
Sbjct: 285 DRQVTITGSAASISLAQYLINVRLSSETG 313



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 50/175 (28%), Positives = 90/175 (51%), Gaps = 19/175 (10%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               I +K+ E   + + T   +  +P  T+        +++VP S  G +IGKGG  +K
Sbjct: 71  AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121

Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
            + E +GA VQ++    P   N  ER +T++G P+   + V+ I   + E P  G
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG 173



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   I G+  +++
Sbjct: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 298


>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
          Length = 331

 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 80/334 (23%), Positives = 142/334 (42%), Gaps = 33/334 (9%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           +++++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G      KA
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
             +II K++ED             ++  + NS     P      V+P A+    L+G   
Sbjct: 72  FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117

Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
             +  +           G+ L   T    T+A    ++      +               
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177

Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGAASPL 381
             P  +++ ++       +  G  A        L  LA        T    G+ G  S  
Sbjct: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIES-- 235

Query: 382 AASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEF 439
           ++  + G     D S      E+ +P +L+G I+G+ G  + E ++++GA+I+I+     
Sbjct: 236 SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP--- 292

Query: 440 VPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 473
           V G+ +R+VTITG+ A+   AQYLI  R++ E G
Sbjct: 293 VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 326



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 50/175 (28%), Positives = 90/175 (51%), Gaps = 19/175 (10%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               I +K+ E   + + T   +  +P  T+        +++VP S  G +IGKGG  +K
Sbjct: 71  AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121

Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
            + E +GA VQ++    P   N  ER +T++G P+   + V+ I   + E P  G
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG 173



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   I G+  +++
Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 311


>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
          Length = 345

 Score = 86.3 bits (212), Expect = 6e-17
 Identities = 86/328 (26%), Positives = 140/328 (42%), Gaps = 43/328 (13%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           +++++     G IIGK G TVK + E+SGA + +S+     N  ER+VT++G  +   KA
Sbjct: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
             +I  K +ED             +   ++NS  T  P      V+P A+    L+G   
Sbjct: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVP-ASQCGSLIGKGG 149

Query: 270 LA------GVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAA 323
                      A   V      N      +   T  +    +  + + + +A     +  
Sbjct: 150 SKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYT---IQG 206

Query: 324 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAA 383
             A  +P     + LA   +     G T     G      L ++  A N   G +S L A
Sbjct: 207 QYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL--PLHSSEEAQN-LMGQSSGLDA 263

Query: 384 SAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT 443
           S    T           E+ +P +L+G I+G+ G  + E ++++GA+I+I+   E   G+
Sbjct: 264 SPPASTH----------ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GS 310

Query: 444 RNRKVTITGTPAATQAAQYLITQRITYE 471
             R++TITGTPA    AQYLI  R+T E
Sbjct: 311 SERQITITGTPANISLAQYLINARLTSE 338



 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 57/185 (30%), Positives = 91/185 (49%), Gaps = 22/185 (11%)

Query: 34  PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
           P+ G    +   E G      +++L+     GSIIGK G+T+ ++++E+GA I +S+   
Sbjct: 27  PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85

Query: 91  FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150
                 ER+  I G  +A+      IA K  E   N     P +   P T         +
Sbjct: 86  ----CPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------L 132

Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRK 208
           +++VP S  G +IGKGG+ +K + E +GA VQ++    P   N  ER VT+SG P+   +
Sbjct: 133 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQ 189

Query: 209 AVELI 213
            V+ I
Sbjct: 190 CVKQI 194



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)

Query: 27  KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83
           K PL +  EA +    ++G D        ++ IP+   G IIG+ G  I ++++ +GA I
Sbjct: 242 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 301

Query: 84  KLSKSKDFYPGTTERVCLIQGT 105
           K++ + +   G++ER   I GT
Sbjct: 302 KIANATE---GSSERQITITGT 320


>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
          Length = 335

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 80/338 (23%), Positives = 146/338 (43%), Gaps = 37/338 (10%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           +++++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G      KA
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
             +II K++ED             ++  + NS     P      V+P A+    L+G   
Sbjct: 72  FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117

Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNL----NTLGLGLSQAAATGALAA 323
             +  +           G+ L   T    T+A    ++      + + + +  +      
Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177

Query: 324 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGA 377
                 P  +++ ++       +  G  A        L  LA        T    G+ G 
Sbjct: 178 VTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGI 237

Query: 378 ASPLAASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISK 435
            S  ++  + G     D S      E+ +P +L+G I+G+ G  + E ++++GA+I+I+ 
Sbjct: 238 ES--SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 295

Query: 436 KGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 473
               V G+ +R+VTITG+ A+   AQYLI  R++ E G
Sbjct: 296 P---VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 330



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 48/179 (26%), Positives = 93/179 (51%), Gaps = 23/179 (12%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  + G   A+  
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               I +K+ E   + + T   +  +P  T+        +++VP S  G +IGKGG  +K
Sbjct: 71  AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121

Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSG 224
            + E +GA VQ++    P   N  ER +T++G P+   + V+    ++++ + + P  G
Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G+T+R   I G+  +++
Sbjct: 261 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 315


>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
          Length = 371

 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 22/199 (11%)

Query: 34  PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
           P+ G    +   E G      +++L+     GSIIGK G+T+ ++++E+GA I +S+   
Sbjct: 27  PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85

Query: 91  FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150
                 ER+  I G  +A+      IA K  E   N     P +   P T         +
Sbjct: 86  ----CPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------L 132

Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRK 208
           +++VP S  G +IGKGG+ +K + E +GA VQ++    P   N  ER VT+SG P+   +
Sbjct: 133 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQ 189

Query: 209 AVELIIQKIQEDPQSGSCL 227
            V+ I   + E P  G+ +
Sbjct: 190 CVKQICVVMLESPPKGATI 208



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 85/337 (25%), Positives = 141/337 (41%), Gaps = 35/337 (10%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           +++++     G IIGK G TVK + E+SGA + +S+     N  ER+VT++G  +   KA
Sbjct: 48  IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 268
             +I  K +ED             +   ++NS  T  P      V+P +   + +  G +
Sbjct: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGS 150

Query: 269 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASA 328
            +  +           G+ L   T    T++     +      +           A    
Sbjct: 151 KIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPY 210

Query: 329 NPAAAAANLLATYASEASASGSTAGGTAGTFA-LGSLAAATAA------TNGYF-GAASP 380
            P  A+  ++       +  G  A         L  LA           TN  F G   P
Sbjct: 211 RPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLP 270

Query: 381 LAASA----ILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQIS 434
           L +S     ++G     D S      E+ +P +L+G I+G+ G  + E ++++GA+I+I+
Sbjct: 271 LHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA 330

Query: 435 KKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 471
              E   G+  R++TITGTPA    AQYLI  R+T E
Sbjct: 331 NATE---GSSERQITITGTPANISLAQYLINARLTSE 364



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)

Query: 27  KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83
           K PL +  EA +    ++G D        ++ IP+   G IIG+ G  I ++++ +GA I
Sbjct: 268 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 327

Query: 84  KLSKSKDFYPGTTERVCLIQGT 105
           K++ + +   G++ER   I GT
Sbjct: 328 KIANATE---GSSERQITITGT 346


>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
          Length = 356

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 87/360 (24%), Positives = 147/360 (40%), Gaps = 57/360 (15%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           +++++     G IIGK G +VK + E+SGA + +S+     N  ER++T++G      KA
Sbjct: 16  IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEG----NCPERIITLTGPTNAIFKA 71

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 268
             +II K++E             ++   + NS     P      V+P     + +  G  
Sbjct: 72  FAMIIDKLEE-------------DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGC 118

Query: 269 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYN------------LNTLG------- 309
            +  +           G+ L   T    T+A    +            L TL        
Sbjct: 119 KIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRV 178

Query: 310 --LGLSQAAATGALAAAAASANPAAAAANLLATYASEA------SASGSTAGGTAGTFAL 361
             +      A+  +  A      + AA    AT+  E       S  G           L
Sbjct: 179 MTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKL 238

Query: 362 GSLA------AATAATNGYFGAASPLAASAILGTEKSTDGSKDVV-EIAVPENLVGAILG 414
             +A      A      G+ G  S  ++  + G   S D S     E+ +P NL+G I+G
Sbjct: 239 NQVARQQSHFAMMHGGTGFAGIDS--SSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296

Query: 415 KGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGV 474
           + G  + E ++++GA+I+I+     V G+  R+VTITG+ A+   AQYLI  R++ E+G+
Sbjct: 297 RQGANINEIRQMSGAQIKIANP---VEGSSGRQVTITGSAASISLAQYLINARLSSEKGM 353



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 56/208 (26%), Positives = 106/208 (50%), Gaps = 28/208 (13%)

Query: 42  TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL 101
           T +G +    +++L+     GSIIGK G+++ ++++E+GA I +S+         ER+  
Sbjct: 6   TESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CPERIIT 60

Query: 102 IQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGL 161
           + G   A+      I +K+ E   N + T   +  +P  T+        +++VP +  G 
Sbjct: 61  LTGPTNAIFKAFAMIIDKLEE-DINSSMTNSTAASRPPVTL--------RLVVPATQCGS 111

Query: 162 IIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQ 215
           +IGKGG  +K + E +GA VQ++    P   N  ER +T++G P+   + V+    ++++
Sbjct: 112 LIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGVPQSVTECVKQICLVMLE 168

Query: 216 KIQEDPQSGSCLNISYANVTGPVANSNP 243
            + + PQ G  + I Y     P+  S+P
Sbjct: 169 TLSQSPQ-GRVMTIPYQ----PMPASSP 191



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%)

Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
           ++ +PN+  G IIG+ GA +  + + SGA ++++   +G +   R VT++G       A 
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS--GRQVTITGSAASISLAQ 340

Query: 211 ELIIQKIQEDPQSG 224
            LI  ++  +   G
Sbjct: 341 YLINARLSSEKGMG 354



 Score = 30.0 bits (66), Expect = 4.9
 Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 3/68 (4%)

Query: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
           ++ IP+   G IIG+ G  I ++++ +GA IK++   +   G++ R   I G+  +++  
Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVE---GSSGRQVTITGSAASISLA 339

Query: 113 HGFIAEKI 120
              I  ++
Sbjct: 340 QYLINARL 347


>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
           isoform b [Homo sapiens]
          Length = 556

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 13/181 (7%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           LK+L  +   G +IGK G+ + +++ ETG  I +S  +D      ER   ++GTVEA  +
Sbjct: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336

Query: 112 VHGFIAEKIREMPQN---VAKTEP--VSILQPQTTVNP-------DRIKQVKIIVPNSTA 159
               I +K+RE  +N      T     S L P     P          + V + +P    
Sbjct: 337 AEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAV 396

Query: 160 GLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
           G IIGK GA +K +   +GA ++++   +G ++ ER+V ++G PE   KA   I  K++E
Sbjct: 397 GAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 455

Query: 220 D 220
           +
Sbjct: 456 E 456



 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 19/177 (10%)

Query: 49  QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
           Q  + + IP+ A G+IIGK G  I QL +  GA+IK++ ++   P  +ER+ +I G  EA
Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441

Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
                G I  K++E           +   P+  V      +  I VP+STAG +IGKGG 
Sbjct: 442 QFKAQGRIFGKLKEE----------NFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGK 487

Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQ 222
           TV  +   + A V + +       +E +V + G     +  ++ +  I+Q++++  Q
Sbjct: 488 TVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 19/200 (9%)

Query: 22  PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
           PP   +R   +  E G     T+      + L++L+P+   G+IIGK G TI  + K+T 
Sbjct: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224

Query: 81  ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
           + + + + ++   G  E+   I  T E  +     I E +++        E + +     
Sbjct: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPL----- 277

Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTV 199
                     KI+  N   G +IGK G  +K +  ++G  + +S   D  I   ER +TV
Sbjct: 278 ----------KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327

Query: 200 SGEPEQNRKAVELIIQKIQE 219
            G  E    A   I++K++E
Sbjct: 328 KGTVEACASAEIEIMKKLRE 347



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 1/71 (1%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           ++I+VP    G IIGK G T+K + +Q+ + V + +K +     E+ VT+   PE   +A
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENS-GAAEKPVTIHATPEGTSEA 254

Query: 210 VELIIQKIQED 220
             +I++ +Q++
Sbjct: 255 CRMILEIMQKE 265



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)

Query: 5   APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
           A I+Q     G  I + P   PD  +R   +  PPEA         G  K  N     E+
Sbjct: 405 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 464

Query: 48  GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
            +    + +PS  AG +IGKGG+T+ +LQ  T A + +   +D  P   E V + I G  
Sbjct: 465 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 522

Query: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
            A          KIRE+ Q V + E
Sbjct: 523 FASQTAQ----RKIREIVQQVKQQE 543



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 2/67 (2%)

Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
           + I VP   VGAI+GK G T+    + T +R+ I +K     G   + VTI  TP  T  
Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253

Query: 460 AQYLITQ 466
           A  +I +
Sbjct: 254 ACRMILE 260



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
           +++V + +P   VGAI+GK G  + +     GA I+I+      P    R V ITG P A
Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441

Query: 457 TQAAQYLITQRITYE 471
              AQ  I  ++  E
Sbjct: 442 QFKAQGRIFGKLKEE 456



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 6/95 (6%)

Query: 390 EKSTDGSKDVVEIAVP----ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
           +K  D +K   EI +       LVG ++GK G+ L + +  TG +I IS   +       
Sbjct: 263 QKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322

Query: 446 RKVTITGTPAATQAAQYLITQRI--TYEQGVRAAN 478
           R +T+ GT  A  +A+  I +++   +E  + A N
Sbjct: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 402 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQ 461
           I VP +  G ++GKGGKT+ E Q LT A + I  + +         V I G   A+Q AQ
Sbjct: 471 IRVPSSTAGRVIGKGGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQ 529

Query: 462 YLITQRITYEQGVRAANPQKV 482
             I + +   +      PQ V
Sbjct: 530 RKIREIVQQVKQQEQKYPQGV 550


>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
          Length = 403

 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           +++++     G IIGK G TVK + EQS A + +S+     +  ER+ T++G       A
Sbjct: 20  LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
           V +I  K+ ED             +    AN      P      V+P A+    L+G A 
Sbjct: 76  VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121

Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
             +  +           G+ L   T    T++     +      +           A   
Sbjct: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181

Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 387
            +P+ +   +L +     +  G +  G  G      +      ++     A+P   S + 
Sbjct: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233

Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447
           G +  T  S    E  VP +L+G ++G+ G  + E ++++GA I+I  + E   G   R 
Sbjct: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288

Query: 448 VTITGTPAATQAAQYLITQRITYEQGVRAANP 479
           VTITG+P +   AQYLIT  +   +      P
Sbjct: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 19/178 (10%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           L++L+     GSIIGK G+T+ ++++++ A I +S+         ER+  I G+  A+  
Sbjct: 20  LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               IA K+ E     A     ++ +P  T+        ++++P S  G +IGK G  +K
Sbjct: 75  AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125

Query: 172 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 227
            + E +GA VQ++    P   N  ER VTVSG P+     V  I   I E P  G+ +
Sbjct: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 63/261 (24%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           L+++IP+   GS+IGK G  I ++++ TGA ++++   D  P +TER   + G  +A+  
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161

Query: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRIKQVK---- 151
               I   I E P                  ++  +  S+      V P  + +++    
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221

Query: 152 ------------------------IIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187
                                    +VPN   G +IG+ G+ +  + + SGA +++  + 
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQA 281

Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG-- 245
           +G    ER VT++G P     A  LI           +CL  +  + +G   +S P    
Sbjct: 282 EGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPADLP 328

Query: 246 SPYANTAEVLPTAAAAAGLLG 266
           +P++     LPT  A  GLLG
Sbjct: 329 APFSPPLTALPT--APPGLLG 347


>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
          Length = 403

 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           +++++     G IIGK G TVK + EQS A + +S+     +  ER+ T++G       A
Sbjct: 20  LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
           V +I  K+ ED             +    AN      P      V+P A+    L+G A 
Sbjct: 76  VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121

Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327
             +  +           G+ L   T    T++     +      +           A   
Sbjct: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181

Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 387
            +P+ +   +L +     +  G +  G  G      +      ++     A+P   S + 
Sbjct: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233

Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447
           G +  T  S    E  VP +L+G ++G+ G  + E ++++GA I+I  + E   G   R 
Sbjct: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288

Query: 448 VTITGTPAATQAAQYLITQRITYEQGVRAANP 479
           VTITG+P +   AQYLIT  +   +      P
Sbjct: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 19/178 (10%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           L++L+     GSIIGK G+T+ ++++++ A I +S+         ER+  I G+  A+  
Sbjct: 20  LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171
               IA K+ E     A     ++ +P  T+        ++++P S  G +IGK G  +K
Sbjct: 75  AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125

Query: 172 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 227
            + E +GA VQ++    P   N  ER VTVSG P+     V  I   I E P  G+ +
Sbjct: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 63/261 (24%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           L+++IP+   GS+IGK G  I ++++ TGA ++++   D  P +TER   + G  +A+  
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161

Query: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRIKQVK---- 151
               I   I E P                  ++  +  S+      V P  + +++    
Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221

Query: 152 ------------------------IIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187
                                    +VPN   G +IG+ G+ +  + + SGA +++  + 
Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQA 281

Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG-- 245
           +G    ER VT++G P     A  LI           +CL  +  + +G   +S P    
Sbjct: 282 EGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPADLP 328

Query: 246 SPYANTAEVLPTAAAAAGLLG 266
           +P++     LPT  A  GLLG
Sbjct: 329 APFSPPLTALPT--APPGLLG 347


>gi|17402900 far upstream element-binding protein [Homo sapiens]
          Length = 644

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 56/211 (26%), Positives = 104/211 (49%), Gaps = 32/211 (15%)

Query: 19  DLDPPDSRKRP-------LEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQT 71
           D D PD++K          + PP      R+   E+ +      +P    G IIG+GG+ 
Sbjct: 69  DGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYK------VPDGMVGFIIGRGGEQ 122

Query: 72  IVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGF---IAEKIREMPQNVA 128
           I ++Q+E+G  I+++       G  ER C++ GT E++ +       I EK R  P    
Sbjct: 123 ISRIQQESGCKIQIAPDSG---GLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHH 179

Query: 129 KTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD 188
              P + +Q             +I++P S AGL+IGKGG T+K + E++G  + + Q   
Sbjct: 180 GDGPGNAVQ-------------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGP 226

Query: 189 GINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
                ++ + ++G+P + ++A E++++ I++
Sbjct: 227 QNTGADKPLRITGDPYKVQQAKEMVLELIRD 257



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 18/195 (9%)

Query: 31  EAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90
           E   E GS    N G D      V IP +A G +IG+ G+ I ++Q + G  I+      
Sbjct: 263 EVRNEYGSRIGGNEGID------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD- 315

Query: 91  FYPGTT-ERVCLIQGTVEALNAVHGFIAEKIREMPQ-NVAKTEPVSILQPQTTVN----- 143
              GTT ER+  I G  +        I + +R +   N     P    + +   N     
Sbjct: 316 ---GTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGP 372

Query: 144 PDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGE 202
           P  +++   IVP    GLIIGKGG T+K++ +QSGA ++L +  P   +   ++ T+ G 
Sbjct: 373 PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGT 432

Query: 203 PEQNRKAVELIIQKI 217
           P+Q   A +LI +KI
Sbjct: 433 PQQIDYARQLIEEKI 447



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 3/66 (4%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
           E  VP+ +VG I+G+GG+ +   Q+ +G +IQI+     +P    R   +TGTP + Q+A
Sbjct: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGTPESVQSA 160

Query: 461 QYLITQ 466
           + L+ Q
Sbjct: 161 KRLLDQ 166



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%)

Query: 399 VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQ 458
           V EI +P +  G ++GKGG+T+ + QE  G ++ + + G    G  ++ + ITG P   Q
Sbjct: 187 VQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA-DKPLRITGDPYKVQ 245

Query: 459 AAQYLITQRITYEQGVR 475
            A+ ++ + I  + G R
Sbjct: 246 QAKEMVLELIRDQGGFR 262



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 22/65 (33%), Positives = 34/65 (52%)

Query: 404 VPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYL 463
           VP    G I+GKGG+T+    + +GARI++ +          +  TI GTP     A+ L
Sbjct: 383 VPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQL 442

Query: 464 ITQRI 468
           I ++I
Sbjct: 443 IEEKI 447



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%)

Query: 395 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 454
           G  + +++ +P   VG ++G+ G+ + + Q   G RIQ        P    R   ITG P
Sbjct: 273 GGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP---ERIAQITGPP 329

Query: 455 AATQAAQYLITQRITYEQGVRAANP 479
              Q A  +IT  +   + V+A NP
Sbjct: 330 DRCQHAAEIITDLL---RSVQAGNP 351


>gi|145312259 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%)

Query: 35  EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
           E+   + T  GED    +++ +P  A   IIG+ G  I QL+K+TGA I +    D    
Sbjct: 39  ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93

Query: 95  TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152
             ERV LI G                   P  V K +     IL   T V+       ++
Sbjct: 94  GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129

Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212
            VP  + G IIG+GG T++++ + SGA +   ++ +G  L  R++ +SG  ++   A  L
Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189

Query: 213 IIQKIQEDPQ 222
           I++K+ ED +
Sbjct: 190 ILEKVSEDEE 199



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458
           +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R + I+GT     
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184

Query: 459 AAQYLITQRITYEQGVR 475
           AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199
           T V  D I ++++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +
Sbjct: 46  TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101

Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234
           SG P Q  KA   I Q + E+      L++   +V
Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136



 Score = 32.7 bits (73), Expect = 0.75
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453
           G  D+ +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G 
Sbjct: 49  GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104

Query: 454 PAATQAAQYLITQRIT 469
           P     A+  I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120


>gi|145312270 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%)

Query: 35  EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
           E+   + T  GED    +++ +P  A   IIG+ G  I QL+K+TGA I +    D    
Sbjct: 39  ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93

Query: 95  TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152
             ERV LI G                   P  V K +     IL   T V+       ++
Sbjct: 94  GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129

Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212
            VP  + G IIG+GG T++++ + SGA +   ++ +G  L  R++ +SG  ++   A  L
Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189

Query: 213 IIQKIQEDPQ 222
           I++K+ ED +
Sbjct: 190 ILEKVSEDEE 199



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458
           +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R + I+GT     
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184

Query: 459 AAQYLITQRITYEQGVR 475
           AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199
           T V  D I ++++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +
Sbjct: 46  TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101

Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234
           SG P Q  KA   I Q + E+      L++   +V
Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136



 Score = 32.7 bits (73), Expect = 0.75
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453
           G  D+ +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G 
Sbjct: 49  GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104

Query: 454 PAATQAAQYLITQRIT 469
           P     A+  I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120


>gi|145312256 tudor and KH domain containing isoform a [Homo
           sapiens]
          Length = 561

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%)

Query: 35  EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94
           E+   + T  GED    +++ +P  A   IIG+ G  I QL+K+TGA I +    D    
Sbjct: 39  ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93

Query: 95  TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152
             ERV LI G                   P  V K +     IL   T V+       ++
Sbjct: 94  GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129

Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212
            VP  + G IIG+GG T++++ + SGA +   ++ +G  L  R++ +SG  ++   A  L
Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189

Query: 213 IIQKIQEDPQ 222
           I++K+ ED +
Sbjct: 190 ILEKVSEDEE 199



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458
           +++VP+  VG I+G+GG+T+    + +GA+I   K+ E   GT   +R + I+GT     
Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184

Query: 459 AAQYLITQRITYEQGVR 475
           AA++LI ++++ ++ +R
Sbjct: 185 AAKHLILEKVSEDEELR 201



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199
           T V  D I ++++ VP     LIIG+ GA +K + +Q+GA + +  +  G    ERV+ +
Sbjct: 46  TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101

Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234
           SG P Q  KA   I Q + E+      L++   +V
Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136



 Score = 32.7 bits (73), Expect = 0.75
 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%)

Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453
           G  D+ +E+ VP+  V  I+G+ G  + + ++ TGARI +  +         R + I+G 
Sbjct: 49  GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104

Query: 454 PAATQAAQYLITQRIT 469
           P     A+  I Q +T
Sbjct: 105 PVQVCKAKAAIHQILT 120


>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
           sapiens]
          Length = 572

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 62/240 (25%), Positives = 105/240 (43%), Gaps = 20/240 (8%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           ++V +P +A G +IG+ G+ I ++Q + G  I+        P   ER   + G  +    
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312

Query: 112 VHGFIAEKI-----REMPQNVAKTEPVSILQPQTTVN-PDRIKQVKIIVPNSTAGLIIGK 165
               I+E I     R+    +A        +   +V  P  ++++   VP    GL+IGK
Sbjct: 313 AAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGK 372

Query: 166 GGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
           GG  +K++ +QSGA V+L +  P   +   R  T+ G P+Q   A +LI +K+       
Sbjct: 373 GGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV------- 425

Query: 225 SCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA---AAAGLLGHANLAGVAAFPAVLS 281
              N+      G    S P   P+ NT     +      AA + G+ +   V+  PA L+
Sbjct: 426 GGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPPAFLT 485



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 45/171 (26%), Positives = 88/171 (51%), Gaps = 19/171 (11%)

Query: 56  IPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVH-- 113
           +P    G IIG+GG+ I ++Q E+G  I+++       G  ER C++ GT E++      
Sbjct: 84  VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS---GIPERPCVLTGTPESIEQAKRL 140

Query: 114 -GFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKA 172
            G I ++ R  P      +  S +Q             +I++P S  GL+IG+GG T+K 
Sbjct: 141 LGQIVDRCRNGPGFHNDIDSNSTIQ-------------EILIPASKVGLVIGRGGETIKQ 187

Query: 173 VMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQS 223
           + E++G  + + Q        ++ + ++G+  + ++A E++++ I+E  Q+
Sbjct: 188 LQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQA 238



 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%)

Query: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
           ++LIP+   G +IG+GG+TI QLQ+ TG  + + +     P   ++   I G    +   
Sbjct: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL-PTGADKPLRITGDAFKVQQA 224

Query: 113 HGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKA 172
              + E IRE  Q   +                    +++ VP    G++IG+ G  +K 
Sbjct: 225 REMVLEIIREKDQADFRGVRGDFNSRMGG------GSIEVSVPRFAVGIVIGRNGEMIKK 278

Query: 173 VMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKI 217
           +   +G  +Q   KPD     ER   V G P++ + A  +I + I
Sbjct: 279 IQNDAGVRIQF--KPDDGISPERAAQVMGPPDRCQHAAHIISELI 321



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
           E  VP+ +VG I+G+GG+ +   Q  +G +IQI+ +   +P    R   +TGTP + + A
Sbjct: 81  EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIP---ERPCVLTGTPESIEQA 137

Query: 461 QYLITQ 466
           + L+ Q
Sbjct: 138 KRLLGQ 143



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 23/81 (28%), Positives = 45/81 (55%), Gaps = 1/81 (1%)

Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447
           G     D +  + EI +P + VG ++G+GG+T+ + QE TG ++ + + G  +P   ++ 
Sbjct: 153 GFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP-LPTGADKP 211

Query: 448 VTITGTPAATQAAQYLITQRI 468
           + ITG     Q A+ ++ + I
Sbjct: 212 LRITGDAFKVQQAREMVLEII 232



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 7/96 (7%)

Query: 120 IREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGA 179
           +++ P +      +  L  Q TV  +  K     VP+   G IIG+GG  +  +  +SG 
Sbjct: 55  VQKRPLDDGVGNQLGALVHQRTVITEEFK-----VPDKMVGFIIGRGGEQISRIQAESGC 109

Query: 180 WVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQ 215
            +Q++ +  GI   ER   ++G PE   +A  L+ Q
Sbjct: 110 KIQIASESSGI--PERPCVLTGTPESIEQAKRLLGQ 143



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 18/74 (24%), Positives = 36/74 (48%)

Query: 395 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 454
           G    +   VP +  G ++GKGG+ +    + +GA +++ +          R+ TI G P
Sbjct: 352 GGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVP 411

Query: 455 AATQAAQYLITQRI 468
              + A+ LI +++
Sbjct: 412 QQIEVARQLIDEKV 425



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%)

Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
           +E++VP   VG ++G+ G+ + + Q   G RIQ        P    R   + G P   Q 
Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312

Query: 460 AQYLITQRITYEQ 472
           A ++I++ I   Q
Sbjct: 313 AAHIISELILTAQ 325


>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%)

Query: 27  KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
           KRP E   E  + KR+    D    L++L+ S  AG++IGKGG+ I  L+ +  A++ + 
Sbjct: 21  KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79

Query: 87  KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137
            S        ER+  I   +E +  +   I   + E   +P   A      +++ V  L 
Sbjct: 80  DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134

Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195
            Q     D   ++++++  S AG IIG  GA +K + E +   ++L Q+  P   +  +R
Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191

Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
           VV + G+P++  + +++I+  I E P  G
Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
           ++ +P++L G+I+GKGG+ + + +  +GA I+I    E + G+ +R +TITGT    Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447

Query: 461 QYLITQRI 468
           QYL+   +
Sbjct: 448 QYLLQNSV 455



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  I GT + +   
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447

Query: 113 HGFIAEKIRE 122
              +   +++
Sbjct: 448 QYLLQNSVKQ 457



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)

Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  +G   ++R++T++G  +Q + A 
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448

Query: 211 ELIIQKIQE 219
            L+   +++
Sbjct: 449 YLLQNSVKQ 457


>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
           [Homo sapiens]
          Length = 463

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%)

Query: 27  KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
           KRP E   E  + KR+    D    L++L+ S  AG++IGKGG+ I  L+ +  A++ + 
Sbjct: 21  KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79

Query: 87  KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137
            S        ER+  I   +E +  +   I   + E   +P   A      +++ V  L 
Sbjct: 80  DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134

Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195
            Q     D   ++++++  S AG IIG  GA +K + E +   ++L Q+  P   +  +R
Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191

Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
           VV + G+P++  + +++I+  I E P  G
Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
           ++ +P++L G+I+GKGG+ + + +  +GA I+I    E + G+ +R +TITGT    Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447

Query: 461 QYLITQRITYEQG 473
           QYL+   +    G
Sbjct: 448 QYLLQNSVKQYSG 460



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  I GT + +   
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447

Query: 113 HGFIAEKIRE 122
              +   +++
Sbjct: 448 QYLLQNSVKQ 457



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)

Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  +G   ++R++T++G  +Q + A 
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448

Query: 211 ELIIQKIQE 219
            L+   +++
Sbjct: 449 YLLQNSVKQ 457


>gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a
           [Homo sapiens]
          Length = 464

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%)

Query: 27  KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86
           KRP E   E  + KR+    D    L++L+ S  AG++IGKGG+ I  L+ +  A++ + 
Sbjct: 21  KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79

Query: 87  KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137
            S        ER+  I   +E +  +   I   + E   +P   A      +++ V  L 
Sbjct: 80  DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134

Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195
            Q     D   ++++++  S AG IIG  GA +K + E +   ++L Q+  P   +  +R
Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191

Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224
           VV + G+P++  + +++I+  I E P  G
Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
           ++ +P++L G+I+GKGG+ + + +  +GA I+I    E + G+ +R +TITGT    Q A
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447

Query: 461 QYLITQRI 468
           QYL+   +
Sbjct: 448 QYLLQNSV 455



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%)

Query: 53  KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112
           +V IP   AGSIIGKGGQ I Q++ E+GA+IK+ +  +   G+ +R+  I GT + +   
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447

Query: 113 HGFIAEKIRE 122
              +   +++
Sbjct: 448 QYLLQNSVKQ 457



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%)

Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210
           ++ +P   AG IIGKGG  +K +  +SGA +++ +  +G   ++R++T++G  +Q + A 
Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448

Query: 211 ELIIQKIQE 219
            L+   +++
Sbjct: 449 YLLQNSVKQ 457


>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
           isoform a [Homo sapiens]
          Length = 599

 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 19/177 (10%)

Query: 49  QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
           Q  + + IP+ A G+IIGK G  I QL +  GA+IK++ ++   P  +ER+ +I G  EA
Sbjct: 427 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 484

Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
                G I  K++E           +   P+  V      +  I VP+STAG +IGKGG 
Sbjct: 485 QFKAQGRIFGKLKEE----------NFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGK 530

Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQ 222
           TV  +   + A V + +       +E +V + G     +  ++ +  I+Q++++  Q
Sbjct: 531 TVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 104/476 (21%), Positives = 170/476 (35%), Gaps = 62/476 (13%)

Query: 22  PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
           PP   +R   +  E G     T+      + L++L+P+   G+IIGK G TI  + K+T 
Sbjct: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224

Query: 81  ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
           + + + + ++   G  E+   I  T E  +     I E +++        E + +     
Sbjct: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPL----- 277

Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTV 199
                     KI+  N   G +IGK G  +K +  ++G  + +S   D  I   ER +TV
Sbjct: 278 ----------KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327

Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA 259
            G  E    A   I++K++E  ++        AN+  P  N +  G  ++    VL   A
Sbjct: 328 KGTVEACASAEIEIMKKLREAFENDMLAVNQQANLI-PGLNLSALGI-FSTGLSVLSPPA 385

Query: 260 AAAGLLGHANLAGVAAFPAVLSGFTGNDLVA------------ITSALNTLASYGYNLNT 307
              G    A            S    +                I +      + G  +  
Sbjct: 386 GPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGK 445

Query: 308 LGLGLSQAAA-TGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAA 366
            G  + Q A   GA    A +  P  +   ++ T   EA              A G +  
Sbjct: 446 KGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFK-----------AQGRIFG 494

Query: 367 ATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQEL 426
                N +F     +   A +    ST G                ++GKGGKT+ E Q L
Sbjct: 495 KLKEEN-FFNPKEEVKLEAHIRVPSSTAG---------------RVIGKGGKTVNELQNL 538

Query: 427 TGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKV 482
           T A + I  + +         V I G   A+Q AQ  I + +   +      PQ V
Sbjct: 539 TSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGV 593



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)

Query: 5   APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
           A I+Q     G  I + P   PD  +R   +  PPEA         G  K  N     E+
Sbjct: 448 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 507

Query: 48  GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
            +    + +PS  AG +IGKGG+T+ +LQ  T A + +   +D  P   E V + I G  
Sbjct: 508 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 565

Query: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
            A          KIRE+ Q V + E
Sbjct: 566 FASQTAQ----RKIREIVQQVKQQE 586


>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
           [Homo sapiens]
          Length = 579

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 62/210 (29%), Positives = 92/210 (43%), Gaps = 21/210 (10%)

Query: 18  IDLDPPDS-RKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQ 76
           + L PP S    P   PP A +       +     + + IP+ + G+IIGK GQ I QL 
Sbjct: 373 LGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLS 432

Query: 77  KETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSIL 136
           +  GA+IK++ ++   P    R+ +I G  EA     G I  KI+E    V+  E V + 
Sbjct: 433 RFAGASIKIAPAEA--PDAKVRMVIITGPPEAQFKAQGRIYGKIKE-ENFVSPKEEVKL- 488

Query: 137 QPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 196
                       +  I VP+  AG +IGKGG TV  +   S A V + +        + V
Sbjct: 489 ------------EAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVV 536

Query: 197 VTVSGE----PEQNRKAVELIIQKIQEDPQ 222
           V ++G         RK  E++ Q  Q   Q
Sbjct: 537 VKITGHFYACQVAQRKIQEILTQVKQHQQQ 566



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 55/211 (26%), Positives = 100/211 (47%), Gaps = 29/211 (13%)

Query: 21  DPPDSRKRPLEAPP------EAGSTKRTNTGEDGQYF-----LKVLIPSYAAGSIIGKGG 69
           D   +++ PL+ P       + GS+++ + G   +       L++L+P+   G+IIGK G
Sbjct: 156 DEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEG 215

Query: 70  QTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAK 129
            TI  + K+T + I + + ++   G  E+   I  T E  +A    I E + +  Q++  
Sbjct: 216 ATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKF 273

Query: 130 TEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD- 188
           TE + +               KI+  N+  G +IGK G  +K + + +   + +S   + 
Sbjct: 274 TEEIPL---------------KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQEL 318

Query: 189 GINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
            +   ER +TV G  E   KA E I++KI+E
Sbjct: 319 TLYNPERTITVKGNVETCAKAEEEIMKKIRE 349



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 36/202 (17%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           LK+L  +   G +IGK G+ + +++++T   I +S  ++      ER   ++G VE    
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338

Query: 112 VHGFIAEKIREMPQN-------------------VAKTEPVSILQPQTTVNPDRI----- 147
               I +KIRE  +N                   +    P S + P T+  P  +     
Sbjct: 339 AEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYP 398

Query: 148 -------KQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQL--SQKPDGINLQERVVT 198
                  + V + +P  + G IIGK G  +K +   +GA +++  ++ PD    + R+V 
Sbjct: 399 QFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA---KVRMVI 455

Query: 199 VSGEPEQNRKAVELIIQKIQED 220
           ++G PE   KA   I  KI+E+
Sbjct: 456 ITGPPEAQFKAQGRIYGKIKEE 477



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 20/138 (14%)

Query: 7   IQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQ 49
           I+Q     G  I + P   PD++ R   +  PPEA         G  K  N     E+ +
Sbjct: 428 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK 487

Query: 50  YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTVEA 108
               + +PS+AAG +IGKGG+T+ +LQ  + A + +   +D  P   ++V + I G   A
Sbjct: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVV--PRDQTPDENDQVVVKITGHFYA 545

Query: 109 LNAVHGFIAEKIREMPQN 126
                  I E + ++ Q+
Sbjct: 546 CQVAQRKIQEILTQVKQH 563



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 19/73 (26%), Positives = 42/73 (57%), Gaps = 1/73 (1%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           ++++VP    G IIGK GAT++ + +Q+ + + + +K +     E+ +T+   PE    A
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKSITILSTPEGTSAA 256

Query: 210 VELIIQKIQEDPQ 222
            + I++ + ++ Q
Sbjct: 257 CKSILEIMHKEAQ 269



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%)

Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
           + + VP   VGAI+GK G T+    + T ++I + +K     G   + +TI  TP  T A
Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255

Query: 460 A 460
           A
Sbjct: 256 A 256



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%)

Query: 398 DVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAAT 457
           + V + +P   VGAI+GK G+ + +     GA I+I+      P  + R V ITG P A 
Sbjct: 406 ETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAE--APDAKVRMVIITGPPEAQ 463

Query: 458 QAAQYLITQRITYEQGV 474
             AQ  I  +I  E  V
Sbjct: 464 FKAQGRIYGKIKEENFV 480



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%)

Query: 402 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQAA 460
           I VP    G ++GKGGKT+ E Q L+ A + + +  +  P   ++ V  ITG   A Q A
Sbjct: 492 IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPR--DQTPDENDQVVVKITGHFYACQVA 549

Query: 461 QYLITQRIT 469
           Q  I + +T
Sbjct: 550 QRKIQEILT 558



 Score = 37.0 bits (84), Expect = 0.040
 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
           ++I    N VG ++GK G+ L + ++ T  +I IS   E       R +T+ G       
Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338

Query: 460 AQYLITQRI--TYEQGVRAANPQ 480
           A+  I ++I  +YE  + + N Q
Sbjct: 339 AEEEIMKKIRESYENDIASMNLQ 361


>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
          Length = 711

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 47/204 (23%), Positives = 91/204 (44%), Gaps = 21/204 (10%)

Query: 21  DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
           D   S+  P+  PP    T+               +P    G IIG+GG+ I ++Q+++G
Sbjct: 128 DSISSQLGPIHPPPRTSMTEEYR------------VPDGMVGLIIGRGGEQINKIQQDSG 175

Query: 81  ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
             +++S       G  ER   + G  E++      + + +        +  P        
Sbjct: 176 CKVQISPDSG---GLPERSVSLTGAPESVQKAKMMLDDIVSR-----GRGGPPGQFHDNA 227

Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 200
               +   Q +I++P   AGL+IGKGG T+K + E++G  + L Q        ++ + + 
Sbjct: 228 NGGQNGTVQ-EIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRII 286

Query: 201 GEPEQNRKAVELIIQKIQEDPQSG 224
           G+P + ++A E+++  ++E  Q G
Sbjct: 287 GDPYKVQQACEMVMDILRERDQGG 310



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 43/176 (24%), Positives = 82/176 (46%), Gaps = 13/176 (7%)

Query: 52  LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
           + V +P ++ G +IG+ G+ I ++Q + G  I+  +     P   E++  I G  +    
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGP---EKIAHIMGPPDRCEH 381

Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQP--------QTTVNPDRIKQVKIIVPNSTAGLII 163
               I + ++ +            + P        Q    P    ++   +P    GL+I
Sbjct: 382 AARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-GEMTFSIPTHKCGLVI 440

Query: 164 GKGGATVKAVMEQSGAWVQLS-QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQ 218
           G+GG  VKA+ +Q+GA+V++S Q P   +   ++  + G P+Q   A +LI +KI+
Sbjct: 441 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE 496



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 23/73 (31%), Positives = 44/73 (60%), Gaps = 3/73 (4%)

Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460
           E  VP+ +VG I+G+GG+ + + Q+ +G ++QIS     +P    R V++TG P + Q A
Sbjct: 148 EYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLP---ERSVSLTGAPESVQKA 204

Query: 461 QYLITQRITYEQG 473
           + ++   ++  +G
Sbjct: 205 KMMLDDIVSRGRG 217



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 399 VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQ 458
           V EI +P    G ++GKGG+T+ + QE  G ++ + + G       ++ + I G P   Q
Sbjct: 235 VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNV-DKPLRIIGDPYKVQ 293

Query: 459 AA 460
            A
Sbjct: 294 QA 295



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 8/85 (9%)

Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQ 458
           +++ VP + VG ++G+ G+ + + Q   G RIQ  +      GT   K+  I G P   +
Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQD----DGTGPEKIAHIMGPPDRCE 380

Query: 459 AAQYLITQRITYEQGVRAANPQKVG 483
            A  +I   +   Q +R+  P   G
Sbjct: 381 HAARIINDLL---QSLRSGPPGPPG 402



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 21/69 (30%), Positives = 40/69 (57%), Gaps = 6/69 (8%)

Query: 403 AVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVP--GTRNRKV-TITGTPAATQA 459
           ++P +  G ++G+GG+ +    + TGA ++IS++   +P  G  N K+  I G+P     
Sbjct: 430 SIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ---LPPNGDPNFKLFIIRGSPQQIDH 486

Query: 460 AQYLITQRI 468
           A+ LI ++I
Sbjct: 487 AKQLIEEKI 495


>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
           isoform 2 [Homo sapiens]
          Length = 438

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 19/179 (10%)

Query: 49  QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
           Q  ++V IP+ A G+IIGK GQ I QL +   A+IK++  +   P +  R+ +I G  EA
Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 323

Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
                G I  K++E           +   P+  V      +  I VP S AG +IGKGG 
Sbjct: 324 QFKAQGRIYGKLKE----------ENFFGPKEEVK----LETHIRVPASAAGRVIGKGGK 369

Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQSG 224
           TV  +   + A V + +        + +V + G     +  ++ +  I+ ++++  Q G
Sbjct: 370 TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG 428



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 49/213 (23%), Positives = 92/213 (43%), Gaps = 32/213 (15%)

Query: 39  TKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 98
           + R  T +  +  LK+L  +   G +IGK G+ + +++++T   I +S  +D      ER
Sbjct: 127 SNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPER 186

Query: 99  VCLIQGTVEALNAVHGFIAEKIREMPQN-VAKTEPVSILQP------------------- 138
              ++G +E        I +K+RE  +N VA     S L P                   
Sbjct: 187 TITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPP 246

Query: 139 -----------QTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187
                       + +     + V++ +P    G IIGK G  +K +   + A ++++  P
Sbjct: 247 PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA-PP 305

Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQED 220
           +  + + R+V ++G PE   KA   I  K++E+
Sbjct: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)

Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
           +++V++ +P   VGAI+GK G+ + +      A I+I+      P ++ R V ITG P A
Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEA 323

Query: 457 TQAAQYLITQRITYE 471
              AQ  I  ++  E
Sbjct: 324 QFKAQGRIYGKLKEE 338



 Score = 37.0 bits (84), Expect = 0.040
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)

Query: 390 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
           E++  G K+ V+    I VP +  G ++GKGGKT+ E Q LT A + + +  +  P   +
Sbjct: 337 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 394

Query: 446 RK-VTITGTPAATQAAQ 461
           +  V I G   A+Q AQ
Sbjct: 395 QVIVKIIGHFYASQMAQ 411



 Score = 33.9 bits (76), Expect = 0.34
 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 2/93 (2%)

Query: 390 EKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 449
           E++    +  ++I    N VG ++GK G+ L + ++ T  +I IS   +       R +T
Sbjct: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189

Query: 450 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 480
           + G       A+  I +++   YE  V A + Q
Sbjct: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 222


>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
           isoform 1 [Homo sapiens]
          Length = 577

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 19/179 (10%)

Query: 49  QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
           Q  ++V IP+ A G+IIGK GQ I QL +   A+IK++  +   P +  R+ +I G  EA
Sbjct: 405 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 462

Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
                G I  K++E           +   P+  V      +  I VP S AG +IGKGG 
Sbjct: 463 QFKAQGRIYGKLKE----------ENFFGPKEEVK----LETHIRVPASAAGRVIGKGGK 508

Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQSG 224
           TV  +   + A V + +        + +V + G     +  ++ +  I+ ++++  Q G
Sbjct: 509 TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG 567



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 61/269 (22%), Positives = 109/269 (40%), Gaps = 46/269 (17%)

Query: 25  SRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 84
           SR +P +  P A          D    L++L+P+   G+IIGK G TI  + K+T + I 
Sbjct: 173 SRGQPRQGSPVAAGAPAKQQQVDIP--LRLLVPTQYVGAIIGKEGATIRNITKQTQSKID 230

Query: 85  LSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP 144
           + + ++   G  E+   +  T E  ++    I E + +  ++    + V +         
Sbjct: 231 VHRKEN--AGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPL--------- 279

Query: 145 DRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTVSGEP 203
                 KI+  N+  G +IGK G  +K V + +   + +S   D  +   ER +TV G  
Sbjct: 280 ------KILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAI 333

Query: 204 EQNRKAVELIIQKIQED--------------------------PQSGSCLNISYANVTGP 237
           E   +A + I++K++E                           P S S +    ++VTG 
Sbjct: 334 ENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGA 393

Query: 238 VANSNPTGSPYANTAEVLPTAAAAAGLLG 266
              S+   +P     +V   A A   ++G
Sbjct: 394 APYSSFMQAPEQEMVQVFIPAQAVGAIIG 422



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 72/329 (21%), Positives = 131/329 (39%), Gaps = 56/329 (17%)

Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
           ++++VP    G IIGK GAT++ + +Q+ + + + +K +     E+ ++V   PE    A
Sbjct: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKAISVHSTPEGCSSA 256

Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269
            ++I++ + ++ +                            TA+ +P       +L H N
Sbjct: 257 CKMILEIMHKEAKD-------------------------TKTADEVPLK-----ILAHNN 286

Query: 270 LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASAN 329
             G       L G  G +L  +     T  +   +L  L L   +   T   A       
Sbjct: 287 FVGR------LIGKEGRNLKKVEQDTETKITIS-SLQDLTLYNPERTITVKGAIENCCRA 339

Query: 330 PAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAAS---PLAASAI 386
                  +   Y ++ +A    +    G     +LAA      G F A+S   P   S++
Sbjct: 340 EQEIMKKVREAYENDVAAMSLQSHLIPGL----NLAAV-----GLFPASSSAVPPPPSSV 390

Query: 387 LGTEKSTD----GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPG 442
            G    +       +++V++ +P   VGAI+GK G+ + +      A I+I+      P 
Sbjct: 391 TGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPD 448

Query: 443 TRNRKVTITGTPAATQAAQYLITQRITYE 471
           ++ R V ITG P A   AQ  I  ++  E
Sbjct: 449 SKVRMVIITGPPEAQFKAQGRIYGKLKEE 477



 Score = 37.0 bits (84), Expect = 0.040
 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%)

Query: 390 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
           E++  G K+ V+    I VP +  G ++GKGGKT+ E Q LT A + + +  +  P   +
Sbjct: 476 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 533

Query: 446 RK-VTITGTPAATQAAQ 461
           +  V I G   A+Q AQ
Sbjct: 534 QVIVKIIGHFYASQMAQ 550



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 3/95 (3%)

Query: 373 GYFGAASPLAASAILGTEKSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARI 431
           G+     P   S +     +     D+ + + VP   VGAI+GK G T+    + T ++I
Sbjct: 170 GFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKI 229

Query: 432 QISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQ 466
            + +K     G   + +++  TP    +A  +I +
Sbjct: 230 DVHRKEN--AGAAEKAISVHSTPEGCSSACKMILE 262



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 391 KSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 449
           K T  + +V ++I    N VG ++GK G+ L + ++ T  +I IS   +       R +T
Sbjct: 269 KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 328

Query: 450 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 480
           + G       A+  I +++   YE  V A + Q
Sbjct: 329 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 361


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,631,603
Number of Sequences: 37866
Number of extensions: 790990
Number of successful extensions: 5030
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 3507
Number of HSP's gapped (non-prelim): 982
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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