BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo sapiens] (483 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 931 0.0 gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 917 0.0 gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 682 0.0 gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo s... 300 1e-81 gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 108 1e-23 gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 106 4e-23 gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 105 7e-23 gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 103 3e-22 gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 87 4e-17 gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 86 6e-17 gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 86 6e-17 gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 86 1e-16 gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 85 1e-16 gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 82 1e-15 gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 77 3e-14 gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 76 8e-14 gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 76 8e-14 gi|17402900 far upstream element-binding protein [Homo sapiens] 75 2e-13 gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 72 1e-12 gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 72 1e-12 gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 72 1e-12 gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 71 2e-12 gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 70 3e-12 gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 70 3e-12 gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a ... 70 3e-12 gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 69 7e-12 gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 67 5e-11 gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 64 2e-10 gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 61 2e-09 gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 61 2e-09 >gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo sapiens] Length = 483 Score = 931 bits (2405), Expect = 0.0 Identities = 483/483 (100%), Positives = 483/483 (100%) Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60 Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120 Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 180 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAW 180 Query: 181 VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN 240 VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN Sbjct: 181 VQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVAN 240 Query: 241 SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS 300 SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS Sbjct: 241 SNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLAS 300 Query: 301 YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA 360 YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA Sbjct: 301 YGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFA 360 Query: 361 LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL 420 LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL Sbjct: 361 LGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTL 420 Query: 421 VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ 480 VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ Sbjct: 421 VEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQ 480 Query: 481 KVG 483 KVG Sbjct: 481 KVG 483 >gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo sapiens] Length = 507 Score = 917 bits (2370), Expect = 0.0 Identities = 483/507 (95%), Positives = 483/507 (95%), Gaps = 24/507 (4%) Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60 Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120 Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQ------------------------VKIIVPN 156 REMPQNVAKTEPVSILQPQTTVNPDRIKQ VKIIVPN Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPN 180 Query: 157 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 216 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK Sbjct: 181 STAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQK 240 Query: 217 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 276 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF Sbjct: 241 IQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAF 300 Query: 277 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 336 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN Sbjct: 301 PAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAAN 360 Query: 337 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 396 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS Sbjct: 361 LLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGS 420 Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA Sbjct: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480 Query: 457 TQAAQYLITQRITYEQGVRAANPQKVG 483 TQAAQYLITQRITYEQGVRAANPQKVG Sbjct: 481 TQAAQYLITQRITYEQGVRAANPQKVG 507 >gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] Length = 492 Score = 682 bits (1761), Expect = 0.0 Identities = 370/492 (75%), Positives = 409/492 (83%), Gaps = 32/492 (6%) Query: 21 DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80 + PDSRKRPLE PPE TKR+NTGE+G+YFLKVLIPSYAAGSIIGKGGQTIVQLQKETG Sbjct: 4 EAPDSRKRPLETPPEVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 63 Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140 ATIKLSKSKDFYPGTTERVCL+QGT EALNAVH FIAEK+RE+PQ + K E V+ILQPQT Sbjct: 64 ATIKLSKSKDFYPGTTERVCLVQGTAEALNAVHSFIAEKVREIPQAMTKPEVVNILQPQT 123 Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 200 T+NPDR KQ K+IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP+GINLQERVVTVS Sbjct: 124 TMNPDRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVS 183 Query: 201 GEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLP---- 256 GEPEQ KAV I+QK+QEDPQS SCLNISYANV GPVANSNPTGSPYA+ A+VLP Sbjct: 184 GEPEQVHKAVSAIVQKVQEDPQSSSCLNISYANVAGPVANSNPTGSPYASPADVLPAAAA 243 Query: 257 -TAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQA 315 +AAAA+GLLG A LAGV AFPA L F+G DL+AI++ALNTLASYGYN N+LGLGL+ A Sbjct: 244 ASAAAASGLLGPAGLAGVGAFPAALPAFSGTDLLAISTALNTLASYGYNTNSLGLGLNSA 303 Query: 316 AATGALAAAAASANP-AAAAANLLATYASEASASGSTAGGTA-----GTFALGSLAAATA 369 AA+G LAA AA ANP AAAAANLLA+YA EA A AGG A ALGS A A A Sbjct: 304 AASGVLAAVAAGANPAAAAAANLLASYAGEAGA--GPAGGAAPPPPPPPGALGSFALA-A 360 Query: 370 ATNGYFGAAS---------PLAASA--------ILGTEK-STDGSKDVVEIAVPENLVGA 411 A NGY GA + PL A+A L EK + + +K++VEIAVPENLVGA Sbjct: 361 AANGYLGAGAGGGAGGGGGPLVAAAAAAGAAGGFLTAEKLAAESAKELVEIAVPENLVGA 420 Query: 412 ILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 471 ILGKGGKTLVEYQELTGARIQISKKGEF+PGTRNR+VTITG+PAATQAAQYLI+QR+TYE Sbjct: 421 ILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYE 480 Query: 472 QGVRAANPQKVG 483 QGVRA+NPQKVG Sbjct: 481 QGVRASNPQKVG 492 >gi|6031189 neuro-oncological ventral antigen 1 isoform 3 [Homo sapiens] Length = 181 Score = 300 bits (769), Expect = 1e-81 Identities = 151/158 (95%), Positives = 152/158 (96%) Query: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA Sbjct: 1 MMAAAPIQQNGTHTGVPIDLDPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYA 60 Query: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI Sbjct: 61 AGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120 Query: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNST 158 REMPQNVAKTEPVSILQPQTTVNPDRIKQ P +T Sbjct: 121 REMPQNVAKTEPVSILQPQTTVNPDRIKQTLPSSPTTT 158 Score = 65.1 bits (157), Expect = 1e-10 Identities = 35/92 (38%), Positives = 53/92 (57%), Gaps = 3/92 (3%) Query: 380 PLAASAILGTEKSTDGSKD---VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKK 436 PL A G+ K T+ +D +++ +P G+I+GKGG+T+V+ Q+ TGA I++SK Sbjct: 29 PLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKS 88 Query: 437 GEFVPGTRNRKVTITGTPAATQAAQYLITQRI 468 +F PGT R I GT A A I ++I Sbjct: 89 KDFYPGTTERVCLIQGTVEALNAVHGFIAEKI 120 Score = 50.8 bits (120), Expect = 3e-06 Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 1/86 (1%) Query: 139 QTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGI-NLQERVV 197 +T D +K+++P+ AG IIGKGG T+ + +++GA ++LS+ D ERV Sbjct: 41 RTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVC 100 Query: 198 TVSGEPEQNRKAVELIIQKIQEDPQS 223 + G E I +KI+E PQ+ Sbjct: 101 LIQGTVEALNAVHGFIAEKIREMPQN 126 >gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] Length = 361 Score = 108 bits (270), Expect = 1e-23 Identities = 109/424 (25%), Positives = 185/424 (43%), Gaps = 85/424 (20%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+ Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 I +K+ E + + T + +P T+ +++VP S G +IGKGG +K Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121 Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNI 229 + E +GA VQ++ P N ER +T++G P+ + V+ I + E P G + I Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG--VTI 176 Query: 230 SYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLV 289 Y P+ SP A G ++ + A+FP Sbjct: 177 PY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP------------ 206 Query: 290 AITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASG 349 +T S N + G L G A P + LA S Sbjct: 207 ------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHFPM-- 254 Query: 350 STAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLV 409 T G + +++ GY+G L ASA + E+ +P +L+ Sbjct: 255 -----THGNTGFSGIESSSPEVKGYWG----LDASAQTTSH----------ELTIPNDLI 295 Query: 410 GAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRIT 469 G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI R++ Sbjct: 296 GCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLINVRLS 352 Query: 470 YEQG 473 E G Sbjct: 353 SETG 356 >gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] Length = 362 Score = 106 bits (265), Expect = 4e-23 Identities = 108/424 (25%), Positives = 184/424 (43%), Gaps = 84/424 (19%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+ Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 I +K+ E + + T + +P T+ +++VP S G +IGKGG +K Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121 Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNI 229 + E +GA VQ++ P N ER +T++G P+ + V+ I + E P G + I Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG--VTI 176 Query: 230 SYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTGNDLV 289 Y P+ SP A G ++ + A+FP Sbjct: 177 PY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP------------ 206 Query: 290 AITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEASASG 349 +T S N + G L G A P + LA S Sbjct: 207 ------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHFPM-- 254 Query: 350 STAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLV 409 T G + +++ GY+ L ASA + E+ +P +L+ Sbjct: 255 -----THGNTGFSGIESSSPEVKGYWAG---LDASAQTTSH----------ELTIPNDLI 296 Query: 410 GAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRIT 469 G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI R++ Sbjct: 297 GCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLINVRLS 353 Query: 470 YEQG 473 E G Sbjct: 354 SETG 357 >gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] Length = 365 Score = 105 bits (263), Expect = 7e-23 Identities = 107/428 (25%), Positives = 188/428 (43%), Gaps = 89/428 (20%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+ Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 I +K+ E + + T + +P T+ +++VP S G +IGKGG +K Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121 Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSGS 225 + E +GA VQ++ P N ER +T++G P+ + V+ ++++ + + P G Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG- 177 Query: 226 CLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTG 285 + I Y P+ SP A G ++ + A+FP Sbjct: 178 -VTIPY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP-------- 210 Query: 286 NDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEA 345 +T S N + G L G A P + LA S Sbjct: 211 ----------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHF 256 Query: 346 SASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVP 405 T G + +++ GY+G L ASA + E+ +P Sbjct: 257 PM-------THGNTGFSGIESSSPEVKGYWG----LDASAQTTSH----------ELTIP 295 Query: 406 ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLIT 465 +L+G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI Sbjct: 296 NDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLIN 352 Query: 466 QRITYEQG 473 R++ E G Sbjct: 353 VRLSSETG 360 >gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] Length = 366 Score = 103 bits (258), Expect = 3e-22 Identities = 106/428 (24%), Positives = 187/428 (43%), Gaps = 88/428 (20%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+ Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 I +K+ E + + T + +P T+ +++VP S G +IGKGG +K Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121 Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSGS 225 + E +GA VQ++ P N ER +T++G P+ + V+ ++++ + + P G Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG- 177 Query: 226 CLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHANLAGVAAFPAVLSGFTG 285 + I Y P+ SP A G ++ + A+FP Sbjct: 178 -VTIPY--------RPKPSSSP----------VIFAGGQDRYSTGSDSASFP-------- 210 Query: 286 NDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASANPAAAAANLLATYASEA 345 +T S N + G L G A P + LA S Sbjct: 211 ----------HTTPSMCLNPDLEGPPLEAYTIQGQYAI----PQPDLTKLHQLAMQQSHF 256 Query: 346 SASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVP 405 T G + +++ GY+ L ASA + E+ +P Sbjct: 257 PM-------THGNTGFSGIESSSPEVKGYWAG---LDASAQTTSH----------ELTIP 296 Query: 406 ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLIT 465 +L+G I+G+ G + E ++++GA+I+I+ V G+ +R+VTITG+ A+ AQYLI Sbjct: 297 NDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGSTDRQVTITGSAASISLAQYLIN 353 Query: 466 QRITYEQG 473 R++ E G Sbjct: 354 VRLSSETG 361 >gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] Length = 318 Score = 86.7 bits (213), Expect = 4e-17 Identities = 80/329 (24%), Positives = 143/329 (43%), Gaps = 36/329 (10%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 +++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269 +II K++ED ++ + NS P V+P A+ L+G Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117 Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327 + + G+ L T T+A ++ + Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177 Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATA---ATNGYFGAASPLAAS 384 P +++ ++ + G A L LA + T+G G ++ L AS Sbjct: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDAS 237 Query: 385 AILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTR 444 A + E+ +P +L+G I+G+ G + E ++++GA+I+I+ V G+ Sbjct: 238 AQTTSH----------ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP---VEGST 284 Query: 445 NRKVTITGTPAATQAAQYLITQRITYEQG 473 +R+VTITG+ A+ AQYLI R++ E G Sbjct: 285 DRQVTITGSAASISLAQYLINVRLSSETG 313 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/175 (28%), Positives = 90/175 (51%), Gaps = 19/175 (10%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+ Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 I +K+ E + + T + +P T+ +++VP S G +IGKGG +K Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121 Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224 + E +GA VQ++ P N ER +T++G P+ + V+ I + E P G Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG 173 Score = 32.0 bits (71), Expect = 1.3 Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110 ++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++ Sbjct: 244 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 298 >gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] Length = 331 Score = 86.3 bits (212), Expect = 6e-17 Identities = 80/334 (23%), Positives = 142/334 (42%), Gaps = 33/334 (9%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 +++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269 +II K++ED ++ + NS P V+P A+ L+G Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117 Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327 + + G+ L T T+A ++ + Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIP 177 Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGAASPL 381 P +++ ++ + G A L LA T G+ G S Sbjct: 178 YRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIES-- 235 Query: 382 AASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEF 439 ++ + G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+ Sbjct: 236 SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANP--- 292 Query: 440 VPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 473 V G+ +R+VTITG+ A+ AQYLI R++ E G Sbjct: 293 VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 326 Score = 74.7 bits (182), Expect = 2e-13 Identities = 50/175 (28%), Positives = 90/175 (51%), Gaps = 19/175 (10%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+ Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 I +K+ E + + T + +P T+ +++VP S G +IGKGG +K Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121 Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224 + E +GA VQ++ P N ER +T++G P+ + V+ I + E P G Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLESPPKG 173 Score = 32.0 bits (71), Expect = 1.3 Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110 ++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++ Sbjct: 257 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 311 >gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] Length = 345 Score = 86.3 bits (212), Expect = 6e-17 Identities = 86/328 (26%), Positives = 140/328 (42%), Gaps = 43/328 (13%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 +++++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + KA Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269 +I K +ED + ++NS T P V+P A+ L+G Sbjct: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVP-ASQCGSLIGKGG 149 Query: 270 LA------GVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAA 323 A V N + T + + + + + +A + Sbjct: 150 SKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLEAYT---IQG 206 Query: 324 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAA 383 A +P + LA + G T G L ++ A N G +S L A Sbjct: 207 QYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKL--PLHSSEEAQN-LMGQSSGLDA 263 Query: 384 SAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT 443 S T E+ +P +L+G I+G+ G + E ++++GA+I+I+ E G+ Sbjct: 264 SPPASTH----------ELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATE---GS 310 Query: 444 RNRKVTITGTPAATQAAQYLITQRITYE 471 R++TITGTPA AQYLI R+T E Sbjct: 311 SERQITITGTPANISLAQYLINARLTSE 338 Score = 80.1 bits (196), Expect = 4e-15 Identities = 57/185 (30%), Positives = 91/185 (49%), Gaps = 22/185 (11%) Query: 34 PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90 P+ G + E G +++L+ GSIIGK G+T+ ++++E+GA I +S+ Sbjct: 27 PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85 Query: 91 FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150 ER+ I G +A+ IA K E N P + P T + Sbjct: 86 ----CPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------L 132 Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRK 208 +++VP S G +IGKGG+ +K + E +GA VQ++ P N ER VT+SG P+ + Sbjct: 133 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQ 189 Query: 209 AVELI 213 V+ I Sbjct: 190 CVKQI 194 Score = 35.4 bits (80), Expect = 0.12 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%) Query: 27 KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83 K PL + EA + ++G D ++ IP+ G IIG+ G I ++++ +GA I Sbjct: 242 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 301 Query: 84 KLSKSKDFYPGTTERVCLIQGT 105 K++ + + G++ER I GT Sbjct: 302 KIANATE---GSSERQITITGT 320 >gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] Length = 335 Score = 85.5 bits (210), Expect = 1e-16 Identities = 80/338 (23%), Positives = 146/338 (43%), Gaps = 37/338 (10%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 +++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEG----NCPERIITLAGPTNAIFKA 71 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269 +II K++ED ++ + NS P V+P A+ L+G Sbjct: 72 FAMIIDKLEED-------------ISSSMTNSTAASRPPVTLRLVVP-ASQCGSLIGKGG 117 Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNL----NTLGLGLSQAAATGALAA 323 + + G+ L T T+A ++ + + + + + Sbjct: 118 CKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177 Query: 324 AAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAA------TAATNGYFGA 377 P +++ ++ + G A L LA T G+ G Sbjct: 178 VTIPYRPKPSSSPVIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGI 237 Query: 378 ASPLAASAILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQISK 435 S ++ + G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+ Sbjct: 238 ES--SSPEVKGYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIAN 295 Query: 436 KGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQG 473 V G+ +R+VTITG+ A+ AQYLI R++ E G Sbjct: 296 P---VEGSTDRQVTITGSAASISLAQYLINVRLSSETG 330 Score = 72.0 bits (175), Expect = 1e-12 Identities = 48/179 (26%), Positives = 93/179 (51%), Gaps = 23/179 (12%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ + G A+ Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGN-----CPERIITLAGPTNAIFK 70 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 I +K+ E + + T + +P T+ +++VP S G +IGKGG +K Sbjct: 71 AFAMIIDKLEEDISS-SMTNSTAASRPPVTL--------RLVVPASQCGSLIGKGGCKIK 121 Query: 172 AVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQKIQEDPQSG 224 + E +GA VQ++ P N ER +T++G P+ + V+ ++++ + + P G Sbjct: 122 EIRESTGAQVQVAGDMLP---NSTERAITIAGIPQSIIECVKQICVVMLETLSQSPPKG 177 Score = 32.0 bits (71), Expect = 1.3 Identities = 17/58 (29%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALN 110 ++ IP+ G IIG+ G I ++++ +GA IK++ + G+T+R I G+ +++ Sbjct: 261 ELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE---GSTDRQVTITGSAASIS 315 >gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] Length = 371 Score = 85.1 bits (209), Expect = 1e-16 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 22/199 (11%) Query: 34 PEAGSTKRTNTGEDG---QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90 P+ G + E G +++L+ GSIIGK G+T+ ++++E+GA I +S+ Sbjct: 27 PQFGRRMESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGN- 85 Query: 91 FYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQV 150 ER+ I G +A+ IA K E N P + P T + Sbjct: 86 ----CPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSNSPATSKPPVT---------L 132 Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRK 208 +++VP S G +IGKGG+ +K + E +GA VQ++ P N ER VT+SG P+ + Sbjct: 133 RLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLP---NSTERAVTISGTPDAIIQ 189 Query: 209 AVELIIQKIQEDPQSGSCL 227 V+ I + E P G+ + Sbjct: 190 CVKQICVVMLESPPKGATI 208 Score = 85.1 bits (209), Expect = 1e-16 Identities = 85/337 (25%), Positives = 141/337 (41%), Gaps = 35/337 (10%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 +++++ G IIGK G TVK + E+SGA + +S+ N ER+VT++G + KA Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEG----NCPERIVTITGPTDAIFKA 103 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 268 +I K +ED + ++NS T P V+P + + + G + Sbjct: 104 FAMIAYKFEED-------------IINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGS 150 Query: 269 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASA 328 + + G+ L T T++ + + A Sbjct: 151 KIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDAIIQCVKQICVVMLESPPKGATIPY 210 Query: 329 NPAAAAANLLATYASEASASGSTAGGTAGTFA-LGSLAAATAA------TNGYF-GAASP 380 P A+ ++ + G A L LA TN F G P Sbjct: 211 RPKPASTPVIFAGGQAYTIQGQYAIPHPDQLTKLHQLAMQQTPFPPLGQTNPAFPGEKLP 270 Query: 381 LAASA----ILGTEKSTDGSKDVV--EIAVPENLVGAILGKGGKTLVEYQELTGARIQIS 434 L +S ++G D S E+ +P +L+G I+G+ G + E ++++GA+I+I+ Sbjct: 271 LHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQIKIA 330 Query: 435 KKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYE 471 E G+ R++TITGTPA AQYLI R+T E Sbjct: 331 NATE---GSSERQITITGTPANISLAQYLINARLTSE 364 Score = 35.4 bits (80), Expect = 0.12 Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%) Query: 27 KRPLEAPPEAGSTKRTNTGEDGQ---YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATI 83 K PL + EA + ++G D ++ IP+ G IIG+ G I ++++ +GA I Sbjct: 268 KLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 327 Query: 84 KLSKSKDFYPGTTERVCLIQGT 105 K++ + + G++ER I GT Sbjct: 328 KIANATE---GSSERQITITGT 346 >gi|222352151 poly(rC) binding protein 1 [Homo sapiens] Length = 356 Score = 82.0 bits (201), Expect = 1e-15 Identities = 87/360 (24%), Positives = 147/360 (40%), Gaps = 57/360 (15%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 +++++ G IIGK G +VK + E+SGA + +S+ N ER++T++G KA Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEG----NCPERIITLTGPTNAIFKA 71 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGL-LGHA 268 +II K++E ++ + NS P V+P + + G Sbjct: 72 FAMIIDKLEE-------------DINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGC 118 Query: 269 NLAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYN------------LNTLG------- 309 + + G+ L T T+A + L TL Sbjct: 119 KIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECVKQICLVMLETLSQSPQGRV 178 Query: 310 --LGLSQAAATGALAAAAASANPAAAAANLLATYASEA------SASGSTAGGTAGTFAL 361 + A+ + A + AA AT+ E S G L Sbjct: 179 MTIPYQPMPASSPVICAGGQDRCSDAAGYPHATHDLEGPPLDAYSIQGQHTISPLDLAKL 238 Query: 362 GSLA------AATAATNGYFGAASPLAASAILGTEKSTDGSKDVV-EIAVPENLVGAILG 414 +A A G+ G S ++ + G S D S E+ +P NL+G I+G Sbjct: 239 NQVARQQSHFAMMHGGTGFAGIDS--SSPEVKGYWASLDASTQTTHELTIPNNLIGCIIG 296 Query: 415 KGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGV 474 + G + E ++++GA+I+I+ V G+ R+VTITG+ A+ AQYLI R++ E+G+ Sbjct: 297 RQGANINEIRQMSGAQIKIANP---VEGSSGRQVTITGSAASISLAQYLINARLSSEKGM 353 Score = 77.0 bits (188), Expect = 3e-14 Identities = 56/208 (26%), Positives = 106/208 (50%), Gaps = 28/208 (13%) Query: 42 TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL 101 T +G + +++L+ GSIIGK G+++ ++++E+GA I +S+ ER+ Sbjct: 6 TESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGN-----CPERIIT 60 Query: 102 IQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGL 161 + G A+ I +K+ E N + T + +P T+ +++VP + G Sbjct: 61 LTGPTNAIFKAFAMIIDKLEE-DINSSMTNSTAASRPPVTL--------RLVVPATQCGS 111 Query: 162 IIGKGGATVKAVMEQSGAWVQLS--QKPDGINLQERVVTVSGEPEQNRKAVE----LIIQ 215 +IGKGG +K + E +GA VQ++ P N ER +T++G P+ + V+ ++++ Sbjct: 112 LIGKGGCKIKEIRESTGAQVQVAGDMLP---NSTERAITIAGVPQSVTECVKQICLVMLE 168 Query: 216 KIQEDPQSGSCLNISYANVTGPVANSNP 243 + + PQ G + I Y P+ S+P Sbjct: 169 TLSQSPQ-GRVMTIPYQ----PMPASSP 191 Score = 37.7 bits (86), Expect = 0.023 Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 2/74 (2%) Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210 ++ +PN+ G IIG+ GA + + + SGA ++++ +G + R VT++G A Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVEGSS--GRQVTITGSAASISLAQ 340 Query: 211 ELIIQKIQEDPQSG 224 LI ++ + G Sbjct: 341 YLINARLSSEKGMG 354 Score = 30.0 bits (66), Expect = 4.9 Identities = 17/68 (25%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112 ++ IP+ G IIG+ G I ++++ +GA IK++ + G++ R I G+ +++ Sbjct: 283 ELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIANPVE---GSSGRQVTITGSAASISLA 339 Query: 113 HGFIAEKI 120 I ++ Sbjct: 340 QYLINARL 347 >gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 isoform b [Homo sapiens] Length = 556 Score = 77.0 bits (188), Expect = 3e-14 Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 13/181 (7%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 LK+L + G +IGK G+ + +++ ETG I +S +D ER ++GTVEA + Sbjct: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336 Query: 112 VHGFIAEKIREMPQN---VAKTEP--VSILQPQTTVNP-------DRIKQVKIIVPNSTA 159 I +K+RE +N T S L P P + V + +P Sbjct: 337 AEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAV 396 Query: 160 GLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQE 219 G IIGK GA +K + +GA ++++ +G ++ ER+V ++G PE KA I K++E Sbjct: 397 GAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 455 Query: 220 D 220 + Sbjct: 456 E 456 Score = 69.3 bits (168), Expect = 7e-12 Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 19/177 (10%) Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108 Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441 Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168 G I K++E + P+ V + I VP+STAG +IGKGG Sbjct: 442 QFKAQGRIFGKLKEE----------NFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGK 487 Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQ 222 TV + + A V + + +E +V + G + ++ + I+Q++++ Q Sbjct: 488 TVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544 Score = 62.4 bits (150), Expect = 9e-10 Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 19/200 (9%) Query: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80 PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T Sbjct: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224 Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140 + + + + ++ G E+ I T E + I E +++ E + + Sbjct: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPL----- 277 Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTV 199 KI+ N G +IGK G +K + ++G + +S D I ER +TV Sbjct: 278 ----------KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327 Query: 200 SGEPEQNRKAVELIIQKIQE 219 G E A I++K++E Sbjct: 328 KGTVEACASAEIEIMKKLRE 347 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 1/71 (1%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 ++I+VP G IIGK G T+K + +Q+ + V + +K + E+ VT+ PE +A Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENS-GAAEKPVTIHATPEGTSEA 254 Query: 210 VELIIQKIQED 220 +I++ +Q++ Sbjct: 255 CRMILEIMQKE 265 Score = 41.2 bits (95), Expect = 0.002 Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%) Query: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47 A I+Q G I + P PD +R + PPEA G K N E+ Sbjct: 405 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 464 Query: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106 + + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G Sbjct: 465 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 522 Query: 107 EALNAVHGFIAEKIREMPQNVAKTE 131 A KIRE+ Q V + E Sbjct: 523 FASQTAQ----RKIREIVQQVKQQE 543 Score = 40.4 bits (93), Expect = 0.004 Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 2/67 (2%) Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459 + I VP VGAI+GK G T+ + T +R+ I +K G + VTI TP T Sbjct: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253 Query: 460 AQYLITQ 466 A +I + Sbjct: 254 ACRMILE 260 Score = 39.7 bits (91), Expect = 0.006 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%) Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456 +++V + +P VGAI+GK G + + GA I+I+ P R V ITG P A Sbjct: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441 Query: 457 TQAAQYLITQRITYE 471 AQ I ++ E Sbjct: 442 QFKAQGRIFGKLKEE 456 Score = 38.9 bits (89), Expect = 0.011 Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 6/95 (6%) Query: 390 EKSTDGSKDVVEIAVP----ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445 +K D +K EI + LVG ++GK G+ L + + TG +I IS + Sbjct: 263 QKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322 Query: 446 RKVTITGTPAATQAAQYLITQRI--TYEQGVRAAN 478 R +T+ GT A +A+ I +++ +E + A N Sbjct: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357 Score = 37.7 bits (86), Expect = 0.023 Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%) Query: 402 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQ 461 I VP + G ++GKGGKT+ E Q LT A + I + + V I G A+Q AQ Sbjct: 471 IRVPSSTAGRVIGKGGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQ 529 Query: 462 YLITQRITYEQGVRAANPQKV 482 I + + + PQ V Sbjct: 530 RKIREIVQQVKQQEQKYPQGV 550 >gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] Length = 403 Score = 75.9 bits (185), Expect = 8e-14 Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 +++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G A Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269 V +I K+ ED + AN P V+P A+ L+G A Sbjct: 76 VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121 Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327 + + G+ L T T++ + + A Sbjct: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181 Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 387 +P+ + +L + + G + G G + ++ A+P S + Sbjct: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233 Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447 G + T S E VP +L+G ++G+ G + E ++++GA I+I + E G R Sbjct: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288 Query: 448 VTITGTPAATQAAQYLITQRITYEQGVRAANP 479 VTITG+P + AQYLIT + + P Sbjct: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320 Score = 70.1 bits (170), Expect = 4e-12 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 19/178 (10%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ I G+ A+ Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 IA K+ E A ++ +P T+ ++++P S G +IGK G +K Sbjct: 75 AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125 Query: 172 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 227 + E +GA VQ++ P N ER VTVSG P+ V I I E P G+ + Sbjct: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180 Score = 63.2 bits (152), Expect = 5e-10 Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 63/261 (24%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 L+++IP+ GS+IGK G I ++++ TGA ++++ D P +TER + G +A+ Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161 Query: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRIKQVK---- 151 I I E P ++ + S+ V P + +++ Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221 Query: 152 ------------------------IIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187 +VPN G +IG+ G+ + + + SGA +++ + Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQA 281 Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG-- 245 +G ER VT++G P A LI +CL + + +G +S P Sbjct: 282 EGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPADLP 328 Query: 246 SPYANTAEVLPTAAAAAGLLG 266 +P++ LPT A GLLG Sbjct: 329 APFSPPLTALPT--APPGLLG 347 >gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] Length = 403 Score = 75.9 bits (185), Expect = 8e-14 Identities = 77/332 (23%), Positives = 132/332 (39%), Gaps = 33/332 (9%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 +++++ G IIGK G TVK + EQS A + +S+ + ER+ T++G A Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEG----SCPERITTITGSTAAVFHA 75 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269 V +I K+ ED + AN P V+P A+ L+G A Sbjct: 76 VSMIAFKLDED-------------LCAAPANGGNVSRPPVTLRLVIP-ASQCGSLIGKAG 121 Query: 270 --LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAAS 327 + + G+ L T T++ + + A Sbjct: 122 TKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIP 181 Query: 328 ANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAASPLAASAIL 387 +P+ + +L + + G + G G + ++ A+P S + Sbjct: 182 YHPSLSLGTVLLS-----ANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATP---SVVP 233 Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447 G + T S E VP +L+G ++G+ G + E ++++GA I+I + E G R Sbjct: 234 GLDPGTQTSSQ--EFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAE---GAGERH 288 Query: 448 VTITGTPAATQAAQYLITQRITYEQGVRAANP 479 VTITG+P + AQYLIT + + P Sbjct: 289 VTITGSPVSIALAQYLITACLETAKSTSGGTP 320 Score = 70.1 bits (170), Expect = 4e-12 Identities = 54/178 (30%), Positives = 88/178 (49%), Gaps = 19/178 (10%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 L++L+ GSIIGK G+T+ ++++++ A I +S+ ER+ I G+ A+ Sbjct: 20 LRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGS-----CPERITTITGSTAAVFH 74 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVK 171 IA K+ E A ++ +P T+ ++++P S G +IGK G +K Sbjct: 75 AVSMIAFKLDE-DLCAAPANGGNVSRPPVTL--------RLVIPASQCGSLIGKAGTKIK 125 Query: 172 AVMEQSGAWVQLSQK--PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCL 227 + E +GA VQ++ P N ER VTVSG P+ V I I E P G+ + Sbjct: 126 EIRETTGAQVQVAGDLLP---NSTERAVTVSGVPDAIILCVRQICAVILESPPKGATI 180 Score = 63.2 bits (152), Expect = 5e-10 Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 63/261 (24%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 L+++IP+ GS+IGK G I ++++ TGA ++++ D P +TER + G +A+ Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIIL 161 Query: 112 VHGFIAEKIREMPQN----------------VAKTEPVSILQPQTTVNPDRIKQVK---- 151 I I E P ++ + S+ V P + +++ Sbjct: 162 CVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSS 221 Query: 152 ------------------------IIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187 +VPN G +IG+ G+ + + + SGA +++ + Sbjct: 222 HAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQA 281 Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTG-- 245 +G ER VT++G P A LI +CL + + +G +S P Sbjct: 282 EGAG--ERHVTITGSPVSIALAQYLIT----------ACLETA-KSTSGGTPSSAPADLP 328 Query: 246 SPYANTAEVLPTAAAAAGLLG 266 +P++ LPT A GLLG Sbjct: 329 APFSPPLTALPT--APPGLLG 347 >gi|17402900 far upstream element-binding protein [Homo sapiens] Length = 644 Score = 74.7 bits (182), Expect = 2e-13 Identities = 56/211 (26%), Positives = 104/211 (49%), Gaps = 32/211 (15%) Query: 19 DLDPPDSRKRP-------LEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQT 71 D D PD++K + PP R+ E+ + +P G IIG+GG+ Sbjct: 69 DGDQPDAKKVAPQNDSFGTQLPPMHQQQSRSVMTEEYK------VPDGMVGFIIGRGGEQ 122 Query: 72 IVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGF---IAEKIREMPQNVA 128 I ++Q+E+G I+++ G ER C++ GT E++ + I EK R P Sbjct: 123 ISRIQQESGCKIQIAPDSG---GLPERSCMLTGTPESVQSAKRLLDQIVEKGRPAPGFHH 179 Query: 129 KTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD 188 P + +Q +I++P S AGL+IGKGG T+K + E++G + + Q Sbjct: 180 GDGPGNAVQ-------------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGP 226 Query: 189 GINLQERVVTVSGEPEQNRKAVELIIQKIQE 219 ++ + ++G+P + ++A E++++ I++ Sbjct: 227 QNTGADKPLRITGDPYKVQQAKEMVLELIRD 257 Score = 73.9 bits (180), Expect = 3e-13 Identities = 60/195 (30%), Positives = 92/195 (47%), Gaps = 18/195 (9%) Query: 31 EAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKD 90 E E GS N G D V IP +A G +IG+ G+ I ++Q + G I+ Sbjct: 263 EVRNEYGSRIGGNEGID------VPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDD- 315 Query: 91 FYPGTT-ERVCLIQGTVEALNAVHGFIAEKIREMPQ-NVAKTEPVSILQPQTTVN----- 143 GTT ER+ I G + I + +R + N P + + N Sbjct: 316 ---GTTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGP 372 Query: 144 PDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGE 202 P +++ IVP GLIIGKGG T+K++ +QSGA ++L + P + ++ T+ G Sbjct: 373 PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGT 432 Query: 203 PEQNRKAVELIIQKI 217 P+Q A +LI +KI Sbjct: 433 PQQIDYARQLIEEKI 447 Score = 47.8 bits (112), Expect = 2e-05 Identities = 24/66 (36%), Positives = 40/66 (60%), Gaps = 3/66 (4%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460 E VP+ +VG I+G+GG+ + Q+ +G +IQI+ +P R +TGTP + Q+A Sbjct: 104 EYKVPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSGGLP---ERSCMLTGTPESVQSA 160 Query: 461 QYLITQ 466 + L+ Q Sbjct: 161 KRLLDQ 166 Score = 45.1 bits (105), Expect = 1e-04 Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%) Query: 399 VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQ 458 V EI +P + G ++GKGG+T+ + QE G ++ + + G G ++ + ITG P Q Sbjct: 187 VQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA-DKPLRITGDPYKVQ 245 Query: 459 AAQYLITQRITYEQGVR 475 A+ ++ + I + G R Sbjct: 246 QAKEMVLELIRDQGGFR 262 Score = 42.0 bits (97), Expect = 0.001 Identities = 22/65 (33%), Positives = 34/65 (52%) Query: 404 VPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYL 463 VP G I+GKGG+T+ + +GARI++ + + TI GTP A+ L Sbjct: 383 VPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQL 442 Query: 464 ITQRI 468 I ++I Sbjct: 443 IEEKI 447 Score = 41.2 bits (95), Expect = 0.002 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 6/85 (7%) Query: 395 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 454 G + +++ +P VG ++G+ G+ + + Q G RIQ P R ITG P Sbjct: 273 GGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGTTP---ERIAQITGPP 329 Query: 455 AATQAAQYLITQRITYEQGVRAANP 479 Q A +IT + + V+A NP Sbjct: 330 DRCQHAAEIITDLL---RSVQAGNP 351 >gi|145312259 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 71.6 bits (174), Expect = 1e-12 Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%) Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94 E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93 Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152 ERV LI G P V K + IL T V+ ++ Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129 Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212 VP + G IIG+GG T++++ + SGA + ++ +G L R++ +SG ++ A L Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189 Query: 213 IIQKIQEDPQ 222 I++K+ ED + Sbjct: 190 ILEKVSEDEE 199 Score = 47.0 bits (110), Expect = 4e-05 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458 +++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184 Query: 459 AAQYLITQRITYEQGVR 475 AA++LI ++++ ++ +R Sbjct: 185 AAKHLILEKVSEDEELR 201 Score = 43.9 bits (102), Expect = 3e-04 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199 T V D I ++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ + Sbjct: 46 TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101 Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234 SG P Q KA I Q + E+ L++ +V Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136 Score = 32.7 bits (73), Expect = 0.75 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%) Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453 G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104 Query: 454 PAATQAAQYLITQRIT 469 P A+ I Q +T Sbjct: 105 PVQVCKAKAAIHQILT 120 >gi|145312270 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 71.6 bits (174), Expect = 1e-12 Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%) Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94 E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93 Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152 ERV LI G P V K + IL T V+ ++ Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129 Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212 VP + G IIG+GG T++++ + SGA + ++ +G L R++ +SG ++ A L Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189 Query: 213 IIQKIQEDPQ 222 I++K+ ED + Sbjct: 190 ILEKVSEDEE 199 Score = 47.0 bits (110), Expect = 4e-05 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458 +++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184 Query: 459 AAQYLITQRITYEQGVR 475 AA++LI ++++ ++ +R Sbjct: 185 AAKHLILEKVSEDEELR 201 Score = 43.9 bits (102), Expect = 3e-04 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199 T V D I ++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ + Sbjct: 46 TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101 Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234 SG P Q KA I Q + E+ L++ +V Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136 Score = 32.7 bits (73), Expect = 0.75 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%) Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453 G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104 Query: 454 PAATQAAQYLITQRIT 469 P A+ I Q +T Sbjct: 105 PVQVCKAKAAIHQILT 120 >gi|145312256 tudor and KH domain containing isoform a [Homo sapiens] Length = 561 Score = 71.6 bits (174), Expect = 1e-12 Identities = 56/190 (29%), Positives = 90/190 (47%), Gaps = 31/190 (16%) Query: 35 EAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 94 E+ + T GED +++ +P A IIG+ G I QL+K+TGA I + D Sbjct: 39 ESREERLTFVGED-DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV----DTEDV 93 Query: 95 TTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPV--SILQPQTTVNPDRIKQVKI 152 ERV LI G P V K + IL T V+ ++ Sbjct: 94 GDERVLLISG------------------FPVQVCKAKAAIHQILTENTPVSE------QL 129 Query: 153 IVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVEL 212 VP + G IIG+GG T++++ + SGA + ++ +G L R++ +SG ++ A L Sbjct: 130 SVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSRLIKISGTQKEVAAAKHL 189 Query: 213 IIQKIQEDPQ 222 I++K+ ED + Sbjct: 190 ILEKVSEDEE 199 Score = 47.0 bits (110), Expect = 4e-05 Identities = 25/77 (32%), Positives = 49/77 (63%), Gaps = 5/77 (6%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGT--RNRKVTITGTPAATQ 458 +++VP+ VG I+G+GG+T+ + +GA+I K+ E GT +R + I+GT Sbjct: 128 QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESE---GTLLLSRLIKISGTQKEVA 184 Query: 459 AAQYLITQRITYEQGVR 475 AA++LI ++++ ++ +R Sbjct: 185 AAKHLILEKVSEDEELR 201 Score = 43.9 bits (102), Expect = 3e-04 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 4/95 (4%) Query: 140 TTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTV 199 T V D I ++++ VP LIIG+ GA +K + +Q+GA + + + G ERV+ + Sbjct: 46 TFVGEDDI-EIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVG---DERVLLI 101 Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANV 234 SG P Q KA I Q + E+ L++ +V Sbjct: 102 SGFPVQVCKAKAAIHQILTENTPVSEQLSVPQRSV 136 Score = 32.7 bits (73), Expect = 0.75 Identities = 22/76 (28%), Positives = 38/76 (50%), Gaps = 5/76 (6%) Query: 395 GSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGT 453 G D+ +E+ VP+ V I+G+ G + + ++ TGARI + + R + I+G Sbjct: 49 GEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDV----GDERVLLISGF 104 Query: 454 PAATQAAQYLITQRIT 469 P A+ I Q +T Sbjct: 105 PVQVCKAKAAIHQILT 120 >gi|100816392 far upstream element (FUSE) binding protein 3 [Homo sapiens] Length = 572 Score = 71.2 bits (173), Expect = 2e-12 Identities = 62/240 (25%), Positives = 105/240 (43%), Gaps = 20/240 (8%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 ++V +P +A G +IG+ G+ I ++Q + G I+ P ER + G + Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312 Query: 112 VHGFIAEKI-----REMPQNVAKTEPVSILQPQTTVN-PDRIKQVKIIVPNSTAGLIIGK 165 I+E I R+ +A + +V P ++++ VP GL+IGK Sbjct: 313 AAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGK 372 Query: 166 GGATVKAVMEQSGAWVQLSQK-PDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQSG 224 GG +K++ +QSGA V+L + P + R T+ G P+Q A +LI +K+ Sbjct: 373 GGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKV------- 425 Query: 225 SCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA---AAAGLLGHANLAGVAAFPAVLS 281 N+ G S P P+ NT + AA + G+ + V+ PA L+ Sbjct: 426 GGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPPAFLT 485 Score = 70.1 bits (170), Expect = 4e-12 Identities = 45/171 (26%), Positives = 88/171 (51%), Gaps = 19/171 (11%) Query: 56 IPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVH-- 113 +P G IIG+GG+ I ++Q E+G I+++ G ER C++ GT E++ Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQIASESS---GIPERPCVLTGTPESIEQAKRL 140 Query: 114 -GFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKA 172 G I ++ R P + S +Q +I++P S GL+IG+GG T+K Sbjct: 141 LGQIVDRCRNGPGFHNDIDSNSTIQ-------------EILIPASKVGLVIGRGGETIKQ 187 Query: 173 VMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQEDPQS 223 + E++G + + Q ++ + ++G+ + ++A E++++ I+E Q+ Sbjct: 188 LQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQA 238 Score = 59.7 bits (143), Expect = 6e-09 Identities = 43/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%) Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112 ++LIP+ G +IG+GG+TI QLQ+ TG + + + P ++ I G + Sbjct: 166 EILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPL-PTGADKPLRITGDAFKVQQA 224 Query: 113 HGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKA 172 + E IRE Q + +++ VP G++IG+ G +K Sbjct: 225 REMVLEIIREKDQADFRGVRGDFNSRMGG------GSIEVSVPRFAVGIVIGRNGEMIKK 278 Query: 173 VMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKI 217 + +G +Q KPD ER V G P++ + A +I + I Sbjct: 279 IQNDAGVRIQF--KPDDGISPERAAQVMGPPDRCQHAAHIISELI 321 Score = 47.0 bits (110), Expect = 4e-05 Identities = 23/66 (34%), Positives = 39/66 (59%), Gaps = 3/66 (4%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460 E VP+ +VG I+G+GG+ + Q +G +IQI+ + +P R +TGTP + + A Sbjct: 81 EFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIP---ERPCVLTGTPESIEQA 137 Query: 461 QYLITQ 466 + L+ Q Sbjct: 138 KRLLGQ 143 Score = 46.2 bits (108), Expect = 7e-05 Identities = 23/81 (28%), Positives = 45/81 (55%), Gaps = 1/81 (1%) Query: 388 GTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRK 447 G D + + EI +P + VG ++G+GG+T+ + QE TG ++ + + G +P ++ Sbjct: 153 GFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGP-LPTGADKP 211 Query: 448 VTITGTPAATQAAQYLITQRI 468 + ITG Q A+ ++ + I Sbjct: 212 LRITGDAFKVQQAREMVLEII 232 Score = 42.4 bits (98), Expect = 0.001 Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 7/96 (7%) Query: 120 IREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGA 179 +++ P + + L Q TV + K VP+ G IIG+GG + + +SG Sbjct: 55 VQKRPLDDGVGNQLGALVHQRTVITEEFK-----VPDKMVGFIIGRGGEQISRIQAESGC 109 Query: 180 WVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQ 215 +Q++ + GI ER ++G PE +A L+ Q Sbjct: 110 KIQIASESSGI--PERPCVLTGTPESIEQAKRLLGQ 143 Score = 40.0 bits (92), Expect = 0.005 Identities = 18/74 (24%), Positives = 36/74 (48%) Query: 395 GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTP 454 G + VP + G ++GKGG+ + + +GA +++ + R+ TI G P Sbjct: 352 GGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVP 411 Query: 455 AATQAAQYLITQRI 468 + A+ LI +++ Sbjct: 412 QQIEVARQLIDEKV 425 Score = 38.1 bits (87), Expect = 0.018 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 3/73 (4%) Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459 +E++VP VG ++G+ G+ + + Q G RIQ P R + G P Q Sbjct: 256 IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISP---ERAAQVMGPPDRCQH 312 Query: 460 AQYLITQRITYEQ 472 A ++I++ I Q Sbjct: 313 AAHIISELILTAQ 325 >gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a [Homo sapiens] Length = 464 Score = 70.5 bits (171), Expect = 3e-12 Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%) Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86 KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ + Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79 Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137 S ER+ I +E + + I + E +P A +++ V L Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134 Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195 Q D ++++++ S AG IIG GA +K + E + ++L Q+ P + +R Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191 Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224 VV + G+P++ + +++I+ I E P G Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220 Score = 51.2 bits (121), Expect = 2e-06 Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460 ++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447 Query: 461 QYLITQRI 468 QYL+ + Sbjct: 448 QYLLQNSV 455 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%) Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112 +V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + + Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447 Query: 113 HGFIAEKIRE 122 + +++ Sbjct: 448 QYLLQNSVKQ 457 Score = 47.0 bits (110), Expect = 4e-05 Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%) Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210 ++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448 Query: 211 ELIIQKIQE 219 L+ +++ Sbjct: 449 YLLQNSVKQ 457 >gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b [Homo sapiens] Length = 463 Score = 70.5 bits (171), Expect = 3e-12 Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%) Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86 KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ + Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79 Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137 S ER+ I +E + + I + E +P A +++ V L Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134 Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195 Q D ++++++ S AG IIG GA +K + E + ++L Q+ P + +R Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191 Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224 VV + G+P++ + +++I+ I E P G Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220 Score = 52.0 bits (123), Expect = 1e-06 Identities = 26/73 (35%), Positives = 45/73 (61%), Gaps = 3/73 (4%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460 ++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447 Query: 461 QYLITQRITYEQG 473 QYL+ + G Sbjct: 448 QYLLQNSVKQYSG 460 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%) Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112 +V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + + Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447 Query: 113 HGFIAEKIRE 122 + +++ Sbjct: 448 QYLLQNSVKQ 457 Score = 47.0 bits (110), Expect = 4e-05 Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%) Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210 ++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448 Query: 211 ELIIQKIQE 219 L+ +++ Sbjct: 449 YLLQNSVKQ 457 >gi|14165437 heterogeneous nuclear ribonucleoprotein K isoform a [Homo sapiens] Length = 464 Score = 70.5 bits (171), Expect = 3e-12 Identities = 57/209 (27%), Positives = 102/209 (48%), Gaps = 20/209 (9%) Query: 27 KRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLS 86 KRP E E + KR+ D L++L+ S AG++IGKGG+ I L+ + A++ + Sbjct: 21 KRPAEDMEEEQAFKRSRN-TDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVP 79 Query: 87 KSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIRE---MPQNVA------KTEPVSILQ 137 S ER+ I +E + + I + E +P A +++ V L Sbjct: 80 DSSG-----PERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLN 134 Query: 138 PQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQK--PDGINLQER 195 Q D ++++++ S AG IIG GA +K + E + ++L Q+ P + +R Sbjct: 135 YQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCP---HSTDR 191 Query: 196 VVTVSGEPEQNRKAVELIIQKIQEDPQSG 224 VV + G+P++ + +++I+ I E P G Sbjct: 192 VVLIGGKPDRVVECIKIILDLISESPIKG 220 Score = 51.2 bits (121), Expect = 2e-06 Identities = 25/68 (36%), Positives = 44/68 (64%), Gaps = 3/68 (4%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460 ++ +P++L G+I+GKGG+ + + + +GA I+I E + G+ +R +TITGT Q A Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID---EPLEGSEDRIITITGTQDQIQNA 447 Query: 461 QYLITQRI 468 QYL+ + Sbjct: 448 QYLLQNSV 455 Score = 48.9 bits (115), Expect = 1e-05 Identities = 25/70 (35%), Positives = 42/70 (60%), Gaps = 3/70 (4%) Query: 53 KVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAV 112 +V IP AGSIIGKGGQ I Q++ E+GA+IK+ + + G+ +R+ I GT + + Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLE---GSEDRIITITGTQDQIQNA 447 Query: 113 HGFIAEKIRE 122 + +++ Sbjct: 448 QYLLQNSVKQ 457 Score = 47.0 bits (110), Expect = 4e-05 Identities = 20/69 (28%), Positives = 43/69 (62%), Gaps = 2/69 (2%) Query: 151 KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAV 210 ++ +P AG IIGKGG +K + +SGA +++ + +G ++R++T++G +Q + A Sbjct: 391 QVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEG--SEDRIITITGTQDQIQNAQ 448 Query: 211 ELIIQKIQE 219 L+ +++ Sbjct: 449 YLLQNSVKQ 457 >gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 isoform a [Homo sapiens] Length = 599 Score = 69.3 bits (168), Expect = 7e-12 Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 19/177 (10%) Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108 Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA Sbjct: 427 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 484 Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168 G I K++E + P+ V + I VP+STAG +IGKGG Sbjct: 485 QFKAQGRIFGKLKEE----------NFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGK 530 Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQ 222 TV + + A V + + +E +V + G + ++ + I+Q++++ Q Sbjct: 531 TVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 587 Score = 63.9 bits (154), Expect = 3e-10 Identities = 104/476 (21%), Positives = 170/476 (35%), Gaps = 62/476 (13%) Query: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80 PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T Sbjct: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224 Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140 + + + + ++ G E+ I T E + I E +++ E + + Sbjct: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPL----- 277 Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTV 199 KI+ N G +IGK G +K + ++G + +S D I ER +TV Sbjct: 278 ----------KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327 Query: 200 SGEPEQNRKAVELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAA 259 G E A I++K++E ++ AN+ P N + G ++ VL A Sbjct: 328 KGTVEACASAEIEIMKKLREAFENDMLAVNQQANLI-PGLNLSALGI-FSTGLSVLSPPA 385 Query: 260 AAAGLLGHANLAGVAAFPAVLSGFTGNDLVA------------ITSALNTLASYGYNLNT 307 G A S + I + + G + Sbjct: 386 GPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGK 445 Query: 308 LGLGLSQAAA-TGALAAAAASANPAAAAANLLATYASEASASGSTAGGTAGTFALGSLAA 366 G + Q A GA A + P + ++ T EA A G + Sbjct: 446 KGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFK-----------AQGRIFG 494 Query: 367 ATAATNGYFGAASPLAASAILGTEKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQEL 426 N +F + A + ST G ++GKGGKT+ E Q L Sbjct: 495 KLKEEN-FFNPKEEVKLEAHIRVPSSTAG---------------RVIGKGGKTVNELQNL 538 Query: 427 TGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQRITYEQGVRAANPQKV 482 T A + I + + V I G A+Q AQ I + + + PQ V Sbjct: 539 TSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGV 593 Score = 41.2 bits (95), Expect = 0.002 Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%) Query: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47 A I+Q G I + P PD +R + PPEA G K N E+ Sbjct: 448 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 507 Query: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106 + + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G Sbjct: 508 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 565 Query: 107 EALNAVHGFIAEKIREMPQNVAKTE 131 A KIRE+ Q V + E Sbjct: 566 FASQTAQ----RKIREIVQQVKQQE 586 >gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 [Homo sapiens] Length = 579 Score = 66.6 bits (161), Expect = 5e-11 Identities = 62/210 (29%), Positives = 92/210 (43%), Gaps = 21/210 (10%) Query: 18 IDLDPPDS-RKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQ 76 + L PP S P PP A + + + + IP+ + G+IIGK GQ I QL Sbjct: 373 LGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGAIIGKQGQHIKQLS 432 Query: 77 KETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSIL 136 + GA+IK++ ++ P R+ +I G EA G I KI+E V+ E V + Sbjct: 433 RFAGASIKIAPAEA--PDAKVRMVIITGPPEAQFKAQGRIYGKIKE-ENFVSPKEEVKL- 488 Query: 137 QPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 196 + I VP+ AG +IGKGG TV + S A V + + + V Sbjct: 489 ------------EAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVV 536 Query: 197 VTVSGE----PEQNRKAVELIIQKIQEDPQ 222 V ++G RK E++ Q Q Q Sbjct: 537 VKITGHFYACQVAQRKIQEILTQVKQHQQQ 566 Score = 65.5 bits (158), Expect = 1e-10 Identities = 55/211 (26%), Positives = 100/211 (47%), Gaps = 29/211 (13%) Query: 21 DPPDSRKRPLEAPP------EAGSTKRTNTGEDGQYF-----LKVLIPSYAAGSIIGKGG 69 D +++ PL+ P + GS+++ + G + L++L+P+ G+IIGK G Sbjct: 156 DEMAAQQNPLQQPRGRRGLGQRGSSRQGSPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEG 215 Query: 70 QTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAK 129 TI + K+T + I + + ++ G E+ I T E +A I E + + Q++ Sbjct: 216 ATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSAACKSILEIMHKEAQDIKF 273 Query: 130 TEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD- 188 TE + + KI+ N+ G +IGK G +K + + + + +S + Sbjct: 274 TEEIPL---------------KILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQEL 318 Query: 189 GINLQERVVTVSGEPEQNRKAVELIIQKIQE 219 + ER +TV G E KA E I++KI+E Sbjct: 319 TLYNPERTITVKGNVETCAKAEEEIMKKIRE 349 Score = 61.2 bits (147), Expect = 2e-09 Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 36/202 (17%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 LK+L + G +IGK G+ + +++++T I +S ++ ER ++G VE Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338 Query: 112 VHGFIAEKIREMPQN-------------------VAKTEPVSILQPQTTVNPDRI----- 147 I +KIRE +N + P S + P T+ P + Sbjct: 339 AEEEIMKKIRESYENDIASMNLQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYP 398 Query: 148 -------KQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQL--SQKPDGINLQERVVT 198 + V + +P + G IIGK G +K + +GA +++ ++ PD + R+V Sbjct: 399 QFEQSETETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAEAPDA---KVRMVI 455 Query: 199 VSGEPEQNRKAVELIIQKIQED 220 ++G PE KA I KI+E+ Sbjct: 456 ITGPPEAQFKAQGRIYGKIKEE 477 Score = 42.0 bits (97), Expect = 0.001 Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 20/138 (14%) Query: 7 IQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGEDGQ 49 I+Q G I + P PD++ R + PPEA G K N E+ + Sbjct: 428 IKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENFVSPKEEVK 487 Query: 50 YFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTVEA 108 + +PS+AAG +IGKGG+T+ +LQ + A + + +D P ++V + I G A Sbjct: 488 LEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVV--PRDQTPDENDQVVVKITGHFYA 545 Query: 109 LNAVHGFIAEKIREMPQN 126 I E + ++ Q+ Sbjct: 546 CQVAQRKIQEILTQVKQH 563 Score = 40.4 bits (93), Expect = 0.004 Identities = 19/73 (26%), Positives = 42/73 (57%), Gaps = 1/73 (1%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 ++++VP G IIGK GAT++ + +Q+ + + + +K + E+ +T+ PE A Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKSITILSTPEGTSAA 256 Query: 210 VELIIQKIQEDPQ 222 + I++ + ++ Q Sbjct: 257 CKSILEIMHKEAQ 269 Score = 40.0 bits (92), Expect = 0.005 Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 2/61 (3%) Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459 + + VP VGAI+GK G T+ + T ++I + +K G + +TI TP T A Sbjct: 198 LRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKEN--AGAAEKSITILSTPEGTSA 255 Query: 460 A 460 A Sbjct: 256 A 256 Score = 39.7 bits (91), Expect = 0.006 Identities = 27/77 (35%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Query: 398 DVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAAT 457 + V + +P VGAI+GK G+ + + GA I+I+ P + R V ITG P A Sbjct: 406 ETVHLFIPALSVGAIIGKQGQHIKQLSRFAGASIKIAPAE--APDAKVRMVIITGPPEAQ 463 Query: 458 QAAQYLITQRITYEQGV 474 AQ I +I E V Sbjct: 464 FKAQGRIYGKIKEENFV 480 Score = 37.7 bits (86), Expect = 0.023 Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%) Query: 402 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQAA 460 I VP G ++GKGGKT+ E Q L+ A + + + + P ++ V ITG A Q A Sbjct: 492 IRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPR--DQTPDENDQVVVKITGHFYACQVA 549 Query: 461 QYLITQRIT 469 Q I + +T Sbjct: 550 QRKIQEILT 558 Score = 37.0 bits (84), Expect = 0.040 Identities = 23/83 (27%), Positives = 40/83 (48%), Gaps = 2/83 (2%) Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459 ++I N VG ++GK G+ L + ++ T +I IS E R +T+ G Sbjct: 279 LKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAK 338 Query: 460 AQYLITQRI--TYEQGVRAANPQ 480 A+ I ++I +YE + + N Q Sbjct: 339 AEEEIMKKIRESYENDIASMNLQ 361 >gi|154355000 KH-type splicing regulatory protein [Homo sapiens] Length = 711 Score = 64.3 bits (155), Expect = 2e-10 Identities = 47/204 (23%), Positives = 91/204 (44%), Gaps = 21/204 (10%) Query: 21 DPPDSRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80 D S+ P+ PP T+ +P G IIG+GG+ I ++Q+++G Sbjct: 128 DSISSQLGPIHPPPRTSMTEEYR------------VPDGMVGLIIGRGGEQINKIQQDSG 175 Query: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140 +++S G ER + G E++ + + + + P Sbjct: 176 CKVQISPDSG---GLPERSVSLTGAPESVQKAKMMLDDIVSR-----GRGGPPGQFHDNA 227 Query: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVS 200 + Q +I++P AGL+IGKGG T+K + E++G + L Q ++ + + Sbjct: 228 NGGQNGTVQ-EIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRII 286 Query: 201 GEPEQNRKAVELIIQKIQEDPQSG 224 G+P + ++A E+++ ++E Q G Sbjct: 287 GDPYKVQQACEMVMDILRERDQGG 310 Score = 58.5 bits (140), Expect = 1e-08 Identities = 43/176 (24%), Positives = 82/176 (46%), Gaps = 13/176 (7%) Query: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111 + V +P ++ G +IG+ G+ I ++Q + G I+ + P E++ I G + Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTGP---EKIAHIMGPPDRCEH 381 Query: 112 VHGFIAEKIREMPQNVAKTEPVSILQP--------QTTVNPDRIKQVKIIVPNSTAGLII 163 I + ++ + + P Q P ++ +P GL+I Sbjct: 382 AARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPG-GEMTFSIPTHKCGLVI 440 Query: 164 GKGGATVKAVMEQSGAWVQLS-QKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQ 218 G+GG VKA+ +Q+GA+V++S Q P + ++ + G P+Q A +LI +KI+ Sbjct: 441 GRGGENVKAINQQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEEKIE 496 Score = 47.8 bits (112), Expect = 2e-05 Identities = 23/73 (31%), Positives = 44/73 (60%), Gaps = 3/73 (4%) Query: 401 EIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAA 460 E VP+ +VG I+G+GG+ + + Q+ +G ++QIS +P R V++TG P + Q A Sbjct: 148 EYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSGGLP---ERSVSLTGAPESVQKA 204 Query: 461 QYLITQRITYEQG 473 + ++ ++ +G Sbjct: 205 KMMLDDIVSRGRG 217 Score = 35.4 bits (80), Expect = 0.12 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 1/62 (1%) Query: 399 VVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQ 458 V EI +P G ++GKGG+T+ + QE G ++ + + G ++ + I G P Q Sbjct: 235 VQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNV-DKPLRIIGDPYKVQ 293 Query: 459 AA 460 A Sbjct: 294 QA 295 Score = 33.9 bits (76), Expect = 0.34 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 8/85 (9%) Query: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT-ITGTPAATQ 458 +++ VP + VG ++G+ G+ + + Q G RIQ + GT K+ I G P + Sbjct: 325 IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQD----DGTGPEKIAHIMGPPDRCE 380 Query: 459 AAQYLITQRITYEQGVRAANPQKVG 483 A +I + Q +R+ P G Sbjct: 381 HAARIINDLL---QSLRSGPPGPPG 402 Score = 33.5 bits (75), Expect = 0.44 Identities = 21/69 (30%), Positives = 40/69 (57%), Gaps = 6/69 (8%) Query: 403 AVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVP--GTRNRKV-TITGTPAATQA 459 ++P + G ++G+GG+ + + TGA ++IS++ +P G N K+ I G+P Sbjct: 430 SIPTHKCGLVIGRGGENVKAINQQTGAFVEISRQ---LPPNGDPNFKLFIIRGSPQQIDH 486 Query: 460 AQYLITQRI 468 A+ LI ++I Sbjct: 487 AKQLIEEKI 495 >gi|238624257 insulin-like growth factor 2 mRNA binding protein 1 isoform 2 [Homo sapiens] Length = 438 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 19/179 (10%) Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108 Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 323 Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168 G I K++E + P+ V + I VP S AG +IGKGG Sbjct: 324 QFKAQGRIYGKLKE----------ENFFGPKEEVK----LETHIRVPASAAGRVIGKGGK 369 Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQSG 224 TV + + A V + + + +V + G + ++ + I+ ++++ Q G Sbjct: 370 TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG 428 Score = 57.0 bits (136), Expect = 4e-08 Identities = 49/213 (23%), Positives = 92/213 (43%), Gaps = 32/213 (15%) Query: 39 TKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTER 98 + R T + + LK+L + G +IGK G+ + +++++T I +S +D ER Sbjct: 127 SNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPER 186 Query: 99 VCLIQGTVEALNAVHGFIAEKIREMPQN-VAKTEPVSILQP------------------- 138 ++G +E I +K+RE +N VA S L P Sbjct: 187 TITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPP 246 Query: 139 -----------QTTVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKP 187 + + + V++ +P G IIGK G +K + + A ++++ P Sbjct: 247 PPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIA-PP 305 Query: 188 DGINLQERVVTVSGEPEQNRKAVELIIQKIQED 220 + + + R+V ++G PE KA I K++E+ Sbjct: 306 ETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEE 338 Score = 40.0 bits (92), Expect = 0.005 Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%) Query: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456 +++V++ +P VGAI+GK G+ + + A I+I+ P ++ R V ITG P A Sbjct: 266 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPDSKVRMVIITGPPEA 323 Query: 457 TQAAQYLITQRITYE 471 AQ I ++ E Sbjct: 324 QFKAQGRIYGKLKEE 338 Score = 37.0 bits (84), Expect = 0.040 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%) Query: 390 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445 E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P + Sbjct: 337 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 394 Query: 446 RK-VTITGTPAATQAAQ 461 + V I G A+Q AQ Sbjct: 395 QVIVKIIGHFYASQMAQ 411 Score = 33.9 bits (76), Expect = 0.34 Identities = 23/93 (24%), Positives = 43/93 (46%), Gaps = 2/93 (2%) Query: 390 EKSTDGSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 449 E++ + ++I N VG ++GK G+ L + ++ T +I IS + R +T Sbjct: 130 EQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 189 Query: 450 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 480 + G A+ I +++ YE V A + Q Sbjct: 190 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 222 >gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 isoform 1 [Homo sapiens] Length = 577 Score = 61.2 bits (147), Expect = 2e-09 Identities = 50/179 (27%), Positives = 84/179 (46%), Gaps = 19/179 (10%) Query: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108 Q ++V IP+ A G+IIGK GQ I QL + A+IK++ + P + R+ +I G EA Sbjct: 405 QEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPET--PDSKVRMVIITGPPEA 462 Query: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168 G I K++E + P+ V + I VP S AG +IGKGG Sbjct: 463 QFKAQGRIYGKLKE----------ENFFGPKEEVK----LETHIRVPASAAGRVIGKGGK 508 Query: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQSG 224 TV + + A V + + + +V + G + ++ + I+ ++++ Q G Sbjct: 509 TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKG 567 Score = 60.5 bits (145), Expect = 3e-09 Identities = 61/269 (22%), Positives = 109/269 (40%), Gaps = 46/269 (17%) Query: 25 SRKRPLEAPPEAGSTKRTNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIK 84 SR +P + P A D L++L+P+ G+IIGK G TI + K+T + I Sbjct: 173 SRGQPRQGSPVAAGAPAKQQQVDIP--LRLLVPTQYVGAIIGKEGATIRNITKQTQSKID 230 Query: 85 LSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP 144 + + ++ G E+ + T E ++ I E + + ++ + V + Sbjct: 231 VHRKEN--AGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPL--------- 279 Query: 145 DRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTVSGEP 203 KI+ N+ G +IGK G +K V + + + +S D + ER +TV G Sbjct: 280 ------KILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAI 333 Query: 204 EQNRKAVELIIQKIQED--------------------------PQSGSCLNISYANVTGP 237 E +A + I++K++E P S S + ++VTG Sbjct: 334 ENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGA 393 Query: 238 VANSNPTGSPYANTAEVLPTAAAAAGLLG 266 S+ +P +V A A ++G Sbjct: 394 APYSSFMQAPEQEMVQVFIPAQAVGAIIG 422 Score = 53.9 bits (128), Expect = 3e-07 Identities = 72/329 (21%), Positives = 131/329 (39%), Gaps = 56/329 (17%) Query: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209 ++++VP G IIGK GAT++ + +Q+ + + + +K + E+ ++V PE A Sbjct: 198 LRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRK-ENAGAAEKAISVHSTPEGCSSA 256 Query: 210 VELIIQKIQEDPQSGSCLNISYANVTGPVANSNPTGSPYANTAEVLPTAAAAAGLLGHAN 269 ++I++ + ++ + TA+ +P +L H N Sbjct: 257 CKMILEIMHKEAKD-------------------------TKTADEVPLK-----ILAHNN 286 Query: 270 LAGVAAFPAVLSGFTGNDLVAITSALNTLASYGYNLNTLGLGLSQAAATGALAAAAASAN 329 G L G G +L + T + +L L L + T A Sbjct: 287 FVGR------LIGKEGRNLKKVEQDTETKITIS-SLQDLTLYNPERTITVKGAIENCCRA 339 Query: 330 PAAAAANLLATYASEASASGSTAGGTAGTFALGSLAAATAATNGYFGAAS---PLAASAI 386 + Y ++ +A + G +LAA G F A+S P S++ Sbjct: 340 EQEIMKKVREAYENDVAAMSLQSHLIPGL----NLAAV-----GLFPASSSAVPPPPSSV 390 Query: 387 LGTEKSTD----GSKDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPG 442 G + +++V++ +P VGAI+GK G+ + + A I+I+ P Sbjct: 391 TGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPE--TPD 448 Query: 443 TRNRKVTITGTPAATQAAQYLITQRITYE 471 ++ R V ITG P A AQ I ++ E Sbjct: 449 SKVRMVIITGPPEAQFKAQGRIYGKLKEE 477 Score = 37.0 bits (84), Expect = 0.040 Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 7/77 (9%) Query: 390 EKSTDGSKDVVE----IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445 E++ G K+ V+ I VP + G ++GKGGKT+ E Q LT A + + + + P + Sbjct: 476 EENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPR--DQTPDEND 533 Query: 446 RK-VTITGTPAATQAAQ 461 + V I G A+Q AQ Sbjct: 534 QVIVKIIGHFYASQMAQ 550 Score = 35.4 bits (80), Expect = 0.12 Identities = 22/95 (23%), Positives = 42/95 (44%), Gaps = 3/95 (3%) Query: 373 GYFGAASPLAASAILGTEKSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARI 431 G+ P S + + D+ + + VP VGAI+GK G T+ + T ++I Sbjct: 170 GFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKI 229 Query: 432 QISKKGEFVPGTRNRKVTITGTPAATQAAQYLITQ 466 + +K G + +++ TP +A +I + Sbjct: 230 DVHRKEN--AGAAEKAISVHSTPEGCSSACKMILE 262 Score = 33.5 bits (75), Expect = 0.44 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 3/93 (3%) Query: 391 KSTDGSKDV-VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVT 449 K T + +V ++I N VG ++GK G+ L + ++ T +I IS + R +T Sbjct: 269 KDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTIT 328 Query: 450 ITGTPAATQAAQYLITQRI--TYEQGVRAANPQ 480 + G A+ I +++ YE V A + Q Sbjct: 329 VKGAIENCCRAEQEIMKKVREAYENDVAAMSLQ 361 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.127 0.349 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,631,603 Number of Sequences: 37866 Number of extensions: 790990 Number of successful extensions: 5030 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 103 Number of HSP's successfully gapped in prelim test: 135 Number of HSP's that attempted gapping in prelim test: 3507 Number of HSP's gapped (non-prelim): 982 length of query: 483 length of database: 18,247,518 effective HSP length: 106 effective length of query: 377 effective length of database: 14,233,722 effective search space: 5366113194 effective search space used: 5366113194 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.