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Search of human proteins with 56090548
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56090548 insulin-like growth factor binding protein-like 1
[Homo sapiens]
(278 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56090548 insulin-like growth factor binding protein-like 1 [H... 588 e-168
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 225 3e-59
gi|19923632 Kazal-type serine peptidase inhibitor domain 1 precu... 174 8e-44
gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens] 88 9e-18
gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens] 84 1e-16
gi|22129776 HtrA serine peptidase 3 [Homo sapiens] 73 2e-13
gi|144226847 obscurin-like 1 [Homo sapiens] 59 5e-09
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 56 3e-08
gi|193083136 leucine-rich repeat, immunoglobulin-like and transm... 54 2e-07
gi|62243068 insulin-like growth factor binding protein 3 isoform... 51 1e-06
gi|62243248 insulin-like growth factor binding protein 3 isoform... 51 1e-06
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 51 1e-06
gi|118572606 hemicentin 1 [Homo sapiens] 50 2e-06
gi|54873613 agrin [Homo sapiens] 50 2e-06
gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens] 50 2e-06
gi|4507923 WNT1 inducible signaling pathway protein 2 precursor ... 50 3e-06
gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 49 5e-06
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 48 8e-06
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 48 8e-06
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 48 8e-06
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 48 8e-06
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 48 8e-06
gi|134244585 putative neuronal cell adhesion molecule [Homo sapi... 48 8e-06
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 48 1e-05
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 47 2e-05
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 47 2e-05
gi|13994372 keratin associated protein 17-1 [Homo sapiens] 46 3e-05
gi|208022668 endothelial cell-specific molecule 1 isoform b prec... 46 4e-05
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 46 4e-05
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ... 46 4e-05
>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
sapiens]
Length = 278
Score = 588 bits (1516), Expect = e-168
Identities = 278/278 (100%), Positives = 278/278 (100%)
Query: 1 MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISAL 60
MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISAL
Sbjct: 1 MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISAL 60
Query: 61 DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGR 120
DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGR
Sbjct: 61 DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGR 120
Query: 121 SYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRA 180
SYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRA
Sbjct: 121 SYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRA 180
Query: 181 VPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGV 240
VPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGV
Sbjct: 181 VPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGV 240
Query: 241 YQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM 278
YQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM
Sbjct: 241 YQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAPDDRM 278
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 225 bits (574), Expect = 3e-59
Identities = 115/263 (43%), Positives = 141/263 (53%), Gaps = 22/263 (8%)
Query: 11 LLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISALDECGCCARCL 70
LLLLLLPL S CGPC P CP P D CGCC C
Sbjct: 16 LLLLLLPLSSSSSSDT-----------CGPCEPASCPPLPPLGCLLGETRDACGCCPMCA 64
Query: 71 GAEGASCGGRAGGR--CGPGLVCASQ---------AAGAAPEGTGLCVCAQRGTVCGSDG 119
EG CGG GR C PG+ C AA P +G+CVC R VCGSDG
Sbjct: 65 RGEGEPCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDG 124
Query: 120 RSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVR 179
+YPS C LR ++ + + G CE P +V PP+ + NVTGAQV LSCEV
Sbjct: 125 TTYPSGCQLRAASQRAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVI 184
Query: 180 AVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEG 239
+PTPV+ W KV + G Q E LPGD N+A+Q RGGP HE T W+L++PL KED G
Sbjct: 185 GIPTPVLIWNKVKRGHYGVQRTELLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAG 244
Query: 240 VYQCHAANMVGEAESHSTVTVLD 262
Y+CHA+N G+A + + +TV+D
Sbjct: 245 EYECHASNSQGQASASAKITVVD 267
>gi|19923632 Kazal-type serine peptidase inhibitor domain 1
precursor [Homo sapiens]
Length = 304
Score = 174 bits (441), Expect = 8e-44
Identities = 111/288 (38%), Positives = 136/288 (47%), Gaps = 29/288 (10%)
Query: 2 PRLSLLLPLLLLLLLPLLPPL-----SPSLGIRDVGGRR-----PKCGPCRPEGCPAPAP 51
P +L LP+LLLLL+ L PP SP G R C PCRPE C AP
Sbjct: 7 PAAALALPVLLLLLVVLTPPPTGARPSPGPDYLRRGWMRLLAEGEGCAPCRPEECAAPRG 66
Query: 52 CPAPGISALDECGCCARCLGAEGASC----GGRAGGRCGPGLVCASQAAGAAPEGT---G 104
C A + D CGCC C EG C G CG L C G G
Sbjct: 67 CLAGRVR--DACGCCWECANLEGQLCDLDPSAHFYGHCGEQLECRLDTGGDLSRGEVPEP 124
Query: 105 LCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSV 164
LC C + +CGSDG +Y +C L+ AR P A+ L A GPCE P +V P
Sbjct: 125 LCACRSQSPLCGSDGHTYSQICRLQEAARARPDAN---LTVAHPGPCESGPQIVSHPYDT 181
Query: 165 HNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEA 224
NVTG V CEV A P I WRK +G +LPGD +I+VQ RGGP E
Sbjct: 182 WNVTGQDVIFGCEVFAYPMASIEWRK-----DGLDI--QLPGDDPHISVQFRGGPQRFEV 234
Query: 225 TAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSFHFP 272
T W+ I +R DEG Y+C N +G+ E+ +++TVL + S P
Sbjct: 235 TGWLQIQAVRPSDEGTYRCLGRNALGQVEAPASLTVLTPDQLNSTGIP 282
>gi|4506141 HtrA serine peptidase 1 precursor [Homo sapiens]
Length = 480
Score = 87.8 bits (216), Expect = 9e-18
Identities = 59/157 (37%), Positives = 73/157 (46%), Gaps = 10/157 (6%)
Query: 1 MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISAL 60
+PR +LL LLLLL P LS + + P C P CP P P G A
Sbjct: 3 IPRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPD--RCEPARCP-PQPEHCEGGRAR 59
Query: 61 DECGCCARCLGAEGASCGGRAGGRCGPGLVCA------SQAAGAAPEGTGLCVCAQRGTV 114
D CGCC C EGA+CG + G CG GL C + A GLCVCA V
Sbjct: 60 DACGCCEVCGAPEGAACGLQEGP-CGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPV 118
Query: 115 CGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPC 151
CGSD +Y ++C LR +R + R H + + G C
Sbjct: 119 CGSDANTYANLCQLRAASRRSERLHRPPVIVLQRGAC 155
>gi|24308541 HtrA serine peptidase 4 precursor [Homo sapiens]
Length = 476
Score = 84.3 bits (207), Expect = 1e-16
Identities = 53/132 (40%), Positives = 60/132 (45%), Gaps = 9/132 (6%)
Query: 7 LLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKC-GPCRPEGCPAPAPCPAPGISALDECGC 65
LLP LLLLL+P+L + L + P C C+P CPA C D C C
Sbjct: 15 LLPGLLLLLVPVLWAGAEKLHTQ------PSCPAVCQPTRCPALPTCALGTTPVFDLCRC 68
Query: 66 CARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGRSYPSV 125
C C AE CGG G C PGL C P G G VCGSD R+YPS+
Sbjct: 69 CRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLG--GAVCGSDRRTYPSM 126
Query: 126 CALRLRARHTPR 137
CALR R R
Sbjct: 127 CALRAENRAARR 138
>gi|22129776 HtrA serine peptidase 3 [Homo sapiens]
Length = 453
Score = 73.2 bits (178), Expect = 2e-13
Identities = 51/166 (30%), Positives = 65/166 (39%), Gaps = 25/166 (15%)
Query: 1 MPRLSLLLPLLLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISAL 60
M +LLL L L L PP +P DV CP+P PG
Sbjct: 1 MQARALLLAALAALALAREPPAAPCPARCDVSR------------CPSPR---CPGGYVP 45
Query: 61 DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGR 120
D C CC C +EG CGG CG L C GLC C VCG+DG
Sbjct: 46 DLCNCCLVCAASEGEPCGGPLDSPCGESLECVR----------GLCRCRWSHAVCGTDGH 95
Query: 121 SYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHN 166
+Y +VCAL+ +R + + + + G C + PR N
Sbjct: 96 TYANVCALQAASRRALQLSGTPVRQLQKGACPLGLHQLSSPRYKFN 141
>gi|144226847 obscurin-like 1 [Homo sapiens]
Length = 1896
Score = 58.9 bits (141), Expect = 5e-09
Identities = 48/164 (29%), Positives = 68/164 (41%), Gaps = 12/164 (7%)
Query: 98 AAPEGTGLCVCAQRGTVCGSDGRSYPSVCALRLRARHT-PRAHPGHLHKARDGPCEFAPV 156
A P G+ VC R G +Y + L + P P G E APV
Sbjct: 74 ALPTDAGVYVCRARNAA----GEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPV 129
Query: 157 VVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVR 216
+ PRS + GA+V L+C +P P + W K AL+E+ D + A+Q
Sbjct: 130 FLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEK------DGMALDEV-WDSSHFALQPG 182
Query: 217 GGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
A+ + I R D GVY CHA N G A++ + + V
Sbjct: 183 RAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV 226
Score = 50.4 bits (119), Expect = 2e-06
Identities = 37/118 (31%), Positives = 49/118 (41%), Gaps = 16/118 (13%)
Query: 145 KARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEEL 204
KA G P + PR V V+GA+ L C V P PV+ W K + ++ L
Sbjct: 2 KASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERL-SF 60
Query: 205 PGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
P D A +L+ D GVY C A N GEA + + VTVL+
Sbjct: 61 PAD---------------GAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLE 103
Score = 33.1 bits (74), Expect = 0.27
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 24/115 (20%)
Query: 155 PVVVVPPRS---VHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
PV +V PR VH +T V L+CEV PV ++ + E + E G H
Sbjct: 805 PVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEVEESDFVVLENEGPHRR- 863
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKY 266
+++ + D G +QC + G+ ++ TVT+ D+S +
Sbjct: 864 ----------------LVLPATQPSDGGEFQC----VAGDECAYFTVTITDVSSW 898
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 56.2 bits (134), Expect = 3e-08
Identities = 79/318 (24%), Positives = 114/318 (35%), Gaps = 66/318 (20%)
Query: 1 MPRLSLLLPLLLLLLLP----LLP-----------PLSPSLGIRDVGGRRPKCGPCRPEG 45
MP L LLPLLLLL L LLP LSP+L + +C R +
Sbjct: 1 MPALRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERECS--RDQD 58
Query: 46 CPAPAPCPAPGISALDECGCCARCLGAE--GASCGGRAGGRCGPGLVCASQAAGAAP-EG 102
C A C ++ CG + C+ A G+ C G VC Q + +G
Sbjct: 59 CAAAEKC------CINVCGLHS-CVAARFPGSPAAPTTAASC-EGFVCPQQGSDCDIWDG 110
Query: 103 TGLCVCAQR-----GTVCGSDGRSYPSVCALR----LRARHT-----------PRAHPGH 142
+C C R C SDG +Y + C + LR H P + PG
Sbjct: 111 QPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHIVPCKHVLSWPPSSPGP 170
Query: 143 LH---KARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEG-T 198
+ G P + P G L C+V P P +TW K + E
Sbjct: 171 PETTARPTPGAAPVPPALYSSPSPQAVQVGGTASLHCDVSGRPPPAVTWEKQSHQRENLI 230
Query: 199 QALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTV 258
+++ G+ V ++ +++ R ED G+Y C A N G + +
Sbjct: 231 MRPDQMYGNVVVTSI------------GQLVLYNARPEDAGLYTCTARNAAGLLRADFPL 278
Query: 259 TVLDLSKYRSF--HFPAP 274
+V+ R PAP
Sbjct: 279 SVVQREPARDAAPSIPAP 296
>gi|193083136 leucine-rich repeat, immunoglobulin-like and
transmembrane domains 3 [Homo sapiens]
Length = 634
Score = 53.5 bits (127), Expect = 2e-07
Identities = 31/110 (28%), Positives = 50/110 (45%), Gaps = 14/110 (12%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P V+ + + G+ V L C+ PTP ITW + SP ++E P + V ++
Sbjct: 209 PSVMTSATKIMSALGSNVLLRCDATGFPTPQITWTRSDSSPVNYTVIQESPEEGVRWSIM 268
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLS 264
G + +D G Y+C A N+ G +E+ TVTVL ++
Sbjct: 269 SLTG--------------ISSKDAGDYKCKAKNLAGMSEAVVTVTVLGIT 304
>gi|62243068 insulin-like growth factor binding protein 3 isoform b
precursor [Homo sapiens]
Length = 291
Score = 51.2 bits (121), Expect = 1e-06
Identities = 42/115 (36%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 3 RLSLLLPLLLLLLLPLLPPLSPSLGIRDVG-GRRPKCGPCRPEGCPAPAPCPAPGISALD 61
R +L L LL+L PP++ + G G G +C PC AP PA +
Sbjct: 5 RPTLWAAALTLLVLLRGPPVARA-GASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVR 63
Query: 62 E--CGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAP-----EGTGLCVCA 109
E CGCC C +EG CG RCG GL C A P +G GLCV A
Sbjct: 64 EPGCGCCLTCALSEGQPCGIYT-ERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117
>gi|62243248 insulin-like growth factor binding protein 3 isoform a
precursor [Homo sapiens]
Length = 297
Score = 51.2 bits (121), Expect = 1e-06
Identities = 42/115 (36%), Positives = 51/115 (44%), Gaps = 10/115 (8%)
Query: 3 RLSLLLPLLLLLLLPLLPPLSPSLGIRDVG-GRRPKCGPCRPEGCPAPAPCPAPGISALD 61
R +L L LL+L PP++ + G G G +C PC AP PA +
Sbjct: 5 RPTLWAAALTLLVLLRGPPVARA-GASSAGLGPVVRCEPCDARALAQCAPPPAVCAELVR 63
Query: 62 E--CGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAP-----EGTGLCVCA 109
E CGCC C +EG CG RCG GL C A P +G GLCV A
Sbjct: 64 EPGCGCCLTCALSEGQPCGIYT-ERCGSGLRCQPSPDEARPLQALLDGRGLCVNA 117
>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
[Homo sapiens]
Length = 328
Score = 51.2 bits (121), Expect = 1e-06
Identities = 44/134 (32%), Positives = 52/134 (38%), Gaps = 29/134 (21%)
Query: 1 MPRLSL-LLPLLLLLLLPLLPPLSPSLGIRDVGGRRP-----KCGPCRPE---GCPAPAP 51
+PR+ LPL LLPLLP L LG GG +C PC PE C P
Sbjct: 2 LPRVGCPALPLPPPPLLPLLPLLLLLLGASGGGGGARAEVLFRCPPCTPERLAACGPPPV 61
Query: 52 CPAPGISAL--------------DECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAG 97
P ++A+ CGCC+ C EG +CG RCG GL C
Sbjct: 62 APPAAVAAVAGGARMPCAELVREPGCGCCSVCARLEGEACGVYT-PRCGQGLRCYPHPGS 120
Query: 98 AAP-----EGTGLC 106
P G G C
Sbjct: 121 ELPLQALVMGEGTC 134
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 50.4 bits (119), Expect = 2e-06
Identities = 35/109 (32%), Positives = 50/109 (45%), Gaps = 14/109 (12%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
PV + P V G+ V L C V+ P P I WR++ P ++ V+ Q
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFS------VSSISQ 846
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDL 263
+R G A ++N L D+G Y C A N G+ +S +TVTV L
Sbjct: 847 LRTG-------ALFILN-LWASDKGTYICEAENQFGKIQSETTVTVTGL 887
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/128 (31%), Positives = 51/128 (39%), Gaps = 28/128 (21%)
Query: 143 LHKARDGPCEFAPVVVVPPR---------SVHNVT-GAQVGLSCEVRAVPTPVITWRKVT 192
+++A + +F+ V VPP SV NV G V L CE AVP PVITW K
Sbjct: 3038 INQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYK-- 3095
Query: 193 KSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEA 252
G E HV I + G H I D G Y C A N+ G
Sbjct: 3096 ---NGRMITE---STHVEI---LADGQMLH-------IKKAEVSDTGQYVCRAINVAGRD 3139
Query: 253 ESHSTVTV 260
+ + + V
Sbjct: 3140 DKNFHLNV 3147
Score = 40.0 bits (92), Expect = 0.002
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 18/90 (20%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P + + G +V L CEV+++P P+ITW K TQ + H + PS
Sbjct: 1086 PVEISVLAGEEVTLPCEVKSLPPPIITWAK------ETQLISPFSPRHTFL-------PS 1132
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVG 250
+ I R D G+Y C A N+ G
Sbjct: 1133 GS-----MKITETRTSDSGMYLCVATNIAG 1157
Score = 39.7 bits (91), Expect = 0.003
Identities = 36/127 (28%), Positives = 48/127 (37%), Gaps = 26/127 (20%)
Query: 126 CALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPV 185
C R A R H+H+ PV+ P +H + + L CE P+P
Sbjct: 3967 CVARNAAGSAHRHVTLHVHEP--------PVIQPQPSELHVILNNPILLPCEATGTPSPF 4018
Query: 186 ITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHA 245
ITW+K EG + N AV GG + I+ +ED G Y C A
Sbjct: 4019 ITWQK-----EGI----NVNTSGRNHAVLPSGG---------LQISRAVREDAGTYMCVA 4060
Query: 246 ANMVGEA 252
N G A
Sbjct: 4061 QNPAGTA 4067
Score = 38.1 bits (87), Expect = 0.009
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 16/89 (17%)
Query: 172 VGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILIN 231
V L+C+ +P P I W K K E + +LE V++ G S + I
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLE----------VRILSGGSK------LQIA 3212
Query: 232 PLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ D G Y C A+NM G+A+ + +++
Sbjct: 3213 RSQHSDSGNYTCIASNMEGKAQKYYFLSI 3241
Score = 37.7 bits (86), Expect = 0.011
Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 18/100 (18%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
PR + + QV L C+ AVP PVITW + + + T + L G
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR------------ 3675
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
++ IN D Y C A+N+ G+ +TV
Sbjct: 3676 ------YLQINNADLGDTANYTCVASNIAGKTTREFILTV 3709
Score = 37.4 bits (85), Expect = 0.015
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 18/106 (16%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P + P+ + G +V + C + P PVITW K G+ L + G+H
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSK-----GGSTML--VDGEH------ 1217
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
S+ + T + I+ D G+Y C A N+ G E+ T+ V
Sbjct: 1218 ---HVSNPDGT--LSIDQATPSDAGIYTCVATNIAGTDETEITLHV 1258
Score = 36.6 bits (83), Expect = 0.025
Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 24/110 (21%)
Query: 157 VVVPP------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN 210
V VPP ++V + V L C+ A+P P +TW K +G L+
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLK-----DGHPLLK-------- 2146
Query: 211 IAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ G S E + + I + +D G Y C A N+ G+ E + V +
Sbjct: 2147 -----KPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNI 2191
Score = 35.8 bits (81), Expect = 0.042
Identities = 26/90 (28%), Positives = 35/90 (38%), Gaps = 20/90 (22%)
Query: 172 VGLSCEVRAVPTPVITWRKVTKS-PEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILI 230
+ L CE R +P P ITW K + +QAL G +++I
Sbjct: 1565 IKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIP------------------ 1606
Query: 231 NPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ D Y CH AN+ G AE V V
Sbjct: 1607 -RAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 35.8 bits (81), Expect = 0.042
Identities = 22/100 (22%), Positives = 37/100 (37%), Gaps = 18/100 (18%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P + G + L CEV+ +P P +TW K + +E L H+
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHI----------- 2347
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + + D G Y C A N+ G + ++V
Sbjct: 2348 -------LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 35.0 bits (79), Expect = 0.072
Identities = 33/117 (28%), Positives = 40/117 (34%), Gaps = 24/117 (20%)
Query: 146 ARDGPCEFAPVVVVPPRSVHN-------VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGT 198
A D EF V VPP + V V L C +P P ITW K +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTA 1870
Query: 199 QALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESH 255
Q N+ +Q G + I ED G Y C A N GE + H
Sbjct: 1871 QG---------NLKIQSSGRV--------LQIAKTLLEDAGRYTCVATNAAGETQQH 1910
Score = 35.0 bits (79), Expect = 0.072
Identities = 26/90 (28%), Positives = 32/90 (35%), Gaps = 18/90 (20%)
Query: 172 VGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILIN 231
+ L CE A P P +TW K + + LPG V + I
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRV------------------LQIP 2836
Query: 232 PLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+ ED G Y C A N GE V VL
Sbjct: 2837 RAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866
Score = 34.7 bits (78), Expect = 0.094
Identities = 31/113 (27%), Positives = 41/113 (36%), Gaps = 27/113 (23%)
Query: 155 PVVVVPPRSVHNVT---GAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN- 210
P V+ V NV+ L CEV P+P+I W K + Q E VN
Sbjct: 1358 PPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYK-----DNVQVTESSTIQTVNN 1412
Query: 211 --IAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
I R P ED G Y C A N+ G ++ + + VL
Sbjct: 1413 GKILKLFRATP----------------EDAGRYSCKAINIAGTSQKYFNIDVL 1449
Score = 34.3 bits (77), Expect = 0.12
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 18/100 (18%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P+ V + L CE A+P+ ++W K Q L+ DHVNIA +
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYK------DGQPLKS--DDHVNIAA------N 2726
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
H + I + D G Y C A+N+ GE E V +
Sbjct: 2727 GHT----LQIKEAQISDTGRYTCVASNIAGEDELDFDVNI 2762
Score = 34.3 bits (77), Expect = 0.12
Identities = 31/105 (29%), Positives = 40/105 (38%), Gaps = 24/105 (22%)
Query: 152 EFAPVVVVPP------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELP 205
EF V VPP +S+ + L C VPTP ITWRK +G L
Sbjct: 3704 EFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRK-----DGA----VLA 3754
Query: 206 GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVG 250
G+H ++ G ++ I D G Y C A N G
Sbjct: 3755 GNHARYSILENG---------FLHIQSAHVTDTGRYLCMATNAAG 3790
Score = 33.5 bits (75), Expect = 0.21
Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 26/111 (23%)
Query: 157 VVVPPRSVHNVTG-------AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
V VPPR + + G +Q L C +PTP I W+K D+V
Sbjct: 4165 VHVPPR-IRSTEGHYTVNENSQAILPCVADGIPTPAINWKK----------------DNV 4207
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+A + G E +++ + ED G Y C A N GE ++TV
Sbjct: 4208 LLANLL--GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTV 4256
Score = 33.1 bits (74), Expect = 0.27
Identities = 23/94 (24%), Positives = 40/94 (42%), Gaps = 16/94 (17%)
Query: 167 VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATA 226
+ G + L CE +P P + W+K +G+ L + G V++ G
Sbjct: 2209 IEGNLISLLCESSGIPPPNLIWKK-----KGSPVLTDSMG-----RVRILSGGRQ----- 2253
Query: 227 WILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ I+ K D +Y C A+N+ G A+ + V
Sbjct: 2254 -LQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 33.1 bits (74), Expect = 0.27
Identities = 25/100 (25%), Positives = 35/100 (35%), Gaps = 18/100 (18%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P V + + L CE + P ITW K E + + LPG
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRT----------- 2630
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ I ++++ G Y C A N GE H V V
Sbjct: 2631 -------LQILNAQEDNAGRYSCVATNEAGEMIKHYEVKV 2663
Score = 32.7 bits (73), Expect = 0.36
Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 16/93 (17%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P V + G V L C +PTP+I W K K G+ I V G
Sbjct: 3253 PSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIAS--------GETERIRVSANG--- 3301
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAE 253
+ + I D G Y C A N GE +
Sbjct: 3302 -----STLNIYGALTSDTGKYTCVATNPAGEED 3329
Score = 32.7 bits (73), Expect = 0.36
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 19/89 (21%)
Query: 172 VGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILIN 231
+ LSCE +P P ITW K +G +E +I +V S + I
Sbjct: 4096 ITLSCEADGLPPPDITWHK-----DGRAIVE-------SIRQRVLSSGS-------LQIA 4136
Query: 232 PLRKEDEGVYQCHAANMVGEAESHSTVTV 260
++ D G Y C AAN+ G + + + +TV
Sbjct: 4137 FVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 32.7 bits (73), Expect = 0.36
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 19/92 (20%)
Query: 169 GAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWI 228
G L+CEV+ PTP I W + E + + +L + I V
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTV------------- 4410
Query: 229 LINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
ED G Y C A N G E ++T+
Sbjct: 4411 ------NEDAGDYTCVATNEAGVVERSMSLTL 4436
Score = 32.7 bits (73), Expect = 0.36
Identities = 21/96 (21%), Positives = 37/96 (38%), Gaps = 19/96 (19%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P++ + P G ++ L+C+ P P ITW + S + L + + IA
Sbjct: 4440 PIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIA-- 4497
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVG 250
+KED ++C A N++G
Sbjct: 4498 -----------------DAQKEDTSEFECVARNLMG 4516
Score = 32.3 bits (72), Expect = 0.47
Identities = 27/100 (27%), Positives = 39/100 (39%), Gaps = 17/100 (17%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P V V V L C+V+ P P I W K K GD N+ + RG
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGK--------PLFLGD-PNVELLDRG--- 1507
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + R+ D+G YQC +N G+ +T+
Sbjct: 1508 -----QVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 32.3 bits (72), Expect = 0.47
Identities = 27/102 (26%), Positives = 37/102 (36%), Gaps = 21/102 (20%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEG--TQALEELPGDHVNI 211
AP + V V V L CE R +P P +TW K SP + L+ L G +
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLK-DGSPVSSFSNGLQVLSGGRI-- 2067
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAE 253
+ + + D G Y C A N GE +
Sbjct: 2068 ----------------LALTSAQISDTGRYTCVAVNAAGEKQ 2093
Score = 32.3 bits (72), Expect = 0.47
Identities = 23/106 (21%), Positives = 41/106 (38%), Gaps = 16/106 (15%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P + P ++ + Q L+CE +P P I WRK H+ Q
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRK---------------NGHLLNVDQ 3848
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + + ++I+P +D Y+C N G+ + +TV
Sbjct: 3849 NQNSYRLLSSGSLVIISP-SVDDTATYECTVTNGAGDDKRTVDLTV 3893
Score = 32.0 bits (71), Expect = 0.61
Identities = 22/82 (26%), Positives = 31/82 (37%), Gaps = 18/82 (21%)
Query: 172 VGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILIN 231
V L C+ P PVITW K + G+ ++ L + I I
Sbjct: 1938 VQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI------------------IDIE 1979
Query: 232 PLRKEDEGVYQCHAANMVGEAE 253
+ D G+Y+C A N G E
Sbjct: 1980 SAQISDAGIYKCVAINSAGATE 2001
Score = 31.6 bits (70), Expect = 0.80
Identities = 33/127 (25%), Positives = 47/127 (37%), Gaps = 27/127 (21%)
Query: 141 GHLHKARDGPCEFAPVVVVPPRSVHNVTGAQ---VGLSCEVRAVPTPVITWRKVTKSPEG 197
G K D P ++ RS N++ + V L+CE +P P ITW K
Sbjct: 2370 GMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFK------- 2422
Query: 198 TQALEELPGDHVNIAVQVR---GGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAES 254
G V+++ VR GG + + ED G Y C N GE
Sbjct: 2423 -------DGWPVSLSNSVRILSGG-------RMLRLMQTTMEDAGQYTCVVRNAAGEERK 2468
Query: 255 HSTVTVL 261
++VL
Sbjct: 2469 IFGLSVL 2475
Score = 31.2 bits (69), Expect = 1.0
Identities = 29/108 (26%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 155 PVVVVPPRSVHN--VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIA 212
P V+ P+S + V + L+CEV P P ++W K E P
Sbjct: 2963 PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLK-----------NEQPIKLNTNT 3011
Query: 213 VQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ V GG + + I + D G Y C A N GE++ ++TV
Sbjct: 3012 LIVPGGRT-------LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV 3052
Score = 30.8 bits (68), Expect = 1.4
Identities = 24/94 (25%), Positives = 35/94 (37%), Gaps = 18/94 (19%)
Query: 169 GAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWI 228
G+ ++C P P + W + P G A H+ + S H +
Sbjct: 3450 GSSTSMACITDGTPAPSMAWLR-DGQPLGLDA-------HLTV--------STHGMVLQL 3493
Query: 229 LINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
L ED G Y C A+N GE H + VL+
Sbjct: 3494 L--KAETEDSGKYTCIASNEAGEVSKHFILKVLE 3525
Score = 30.4 bits (67), Expect = 1.8
Identities = 31/116 (26%), Positives = 44/116 (37%), Gaps = 26/116 (22%)
Query: 153 FAPVVVVPPRSVHNVT--------GAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEEL 204
F V+VPP V T V L+CEV P P ITW K Q L+E
Sbjct: 2470 FGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHK------DGQPLQED 2523
Query: 205 PGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
H+ + GG ++ I ++ G Y C A++ G ++ V
Sbjct: 2524 EAHHI-----ISGG-------RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 30.4 bits (67), Expect = 1.8
Identities = 21/87 (24%), Positives = 34/87 (39%), Gaps = 18/87 (20%)
Query: 174 LSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPL 233
L+C +P P +TW K + T ++ L G V + I+
Sbjct: 3548 LTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEV------------------LRISTA 3589
Query: 234 RKEDEGVYQCHAANMVGEAESHSTVTV 260
+ ED G Y C A++ G+ + V V
Sbjct: 3590 QVEDTGRYTCLASSPAGDDDKEYLVRV 3616
Score = 29.3 bits (64), Expect = 4.0
Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 18/87 (20%)
Query: 174 LSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPL 233
L C V P P I W K Q ++E G + + G ++I
Sbjct: 1754 LDCHVTGSPPPTIMWLK------DGQLIDERDG----FKILLNGRK--------LVIAQA 1795
Query: 234 RKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + G+Y+C AAN G+ + VTV
Sbjct: 1796 QVSNTGLYRCMAANTAGDHKKEFEVTV 1822
Score = 28.9 bits (63), Expect = 5.2
Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 20/108 (18%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAV-PTPVITWRKVTKSPEGTQALEELPGDHVNIA 212
AP++ + P + + G Q+ L C + A P P W K L+ N
Sbjct: 889 APLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIK-----NSAMLLQ-------NPY 936
Query: 213 VQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ VR S H I ++ +D G Y C A+N+ G ++V V
Sbjct: 937 ITVRSDGSLH-------IERVQLQDGGEYTCVASNVAGTNNKTTSVVV 977
Score = 28.9 bits (63), Expect = 5.2
Identities = 25/101 (24%), Positives = 39/101 (38%), Gaps = 18/101 (17%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P + V + L C+ P+P++TW K +G N +++ G
Sbjct: 1648 PLNKQVVIAHSLTLECKAAGNPSPILTWLK-----DGVPV-------KANDNIRIEAGGK 1695
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
E I ++ D G Y C A ++ GE E V VL
Sbjct: 1696 KLE------IMSAQEIDRGQYICVATSVAGEKEIKYEVDVL 1730
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 50.1 bits (118), Expect = 2e-06
Identities = 54/184 (29%), Positives = 61/184 (33%), Gaps = 48/184 (26%)
Query: 40 PCRPEGCPAPAPCPAPGISALDECGCCARCL-----GAEGASCGGRAG------------ 82
PC C A C A EC L G++G + G
Sbjct: 467 PCLGVQCAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREI 526
Query: 83 --GRCGPGLVCASQAAGAAPEG-TGLCVC-----AQRGTVCGSDGRSYPSVCALRLRARH 134
R GP C GA E TG CVC A VCGSDG +YPS C L + A
Sbjct: 527 QVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHA-- 584
Query: 135 TPRAHPGHLHKARDGPCEFAPVVVV-------------------PPRSVHNVTGAQVGLS 175
H LH A GPCE V PP V G G +
Sbjct: 585 --CTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGSDGVTYGSA 642
Query: 176 CEVR 179
CE+R
Sbjct: 643 CELR 646
Score = 48.1 bits (113), Expect = 8e-06
Identities = 33/85 (38%), Positives = 38/85 (44%), Gaps = 17/85 (20%)
Query: 77 CGGR---AGGRCGPGLVCASQAAGAAPEGTGLCVC------AQRGTVCGSDGRSYPSVCA 127
CG R + C G CA A G T C+C A GTVCGSDG YP C
Sbjct: 242 CGSRDPCSNVTCSFGSTCARSADGL----TASCLCPATCRGAPEGTVCGSDGADYPGECQ 297
Query: 128 LRLRARHTPRAHPGHLHKARDGPCE 152
L RA A ++ K DGPC+
Sbjct: 298 LLRRA----CARQENVFKKFDGPCD 318
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/138 (30%), Positives = 55/138 (39%), Gaps = 26/138 (18%)
Query: 34 RRPKCGPCRPEGCPA-PAP-CPAPGISALDECGCCARCLGAEGASCG--------GRAGG 83
RRP+ RPE CPA AP C G++ ++C +G GA+ G G+ G
Sbjct: 338 RRPEM-LLRPESCPARQAPVCGDDGVTYENDC-----VMGRSGAARGLLLQKVRSGQCQG 391
Query: 84 RCGPGLVCASQAAGAAPEGTGLCVCAQ------RGTVCGSDGRSYPSVCALRLRARHTPR 137
R C A + G C C + VC DGR+Y S C + R
Sbjct: 392 RDQCPEPCRFNAVCLSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQR 451
Query: 138 AHPGHLHKARDGPCEFAP 155
A P GPC+ AP
Sbjct: 452 AIP----SKHQGPCDQAP 465
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/140 (30%), Positives = 55/140 (39%), Gaps = 19/140 (13%)
Query: 55 PGISALDECGCC--ARCLGAEGASCGGRAGGRCGPGLVCASQAAGAAPEGTGLCVC---- 108
PG++ +CG C R LG G A C + C A G+ CVC
Sbjct: 870 PGVAG-PKCGQCPDGRALGPAGCEADASAPATCAE-MRCEFGARCVEESGSAHCVCPMLT 927
Query: 109 ---AQRGTVCGSDGRSYPSVCALRLRARHTPRAHPG-HLHKARDGPCEFAPVVVVPPRSV 164
A VCGSDG +Y + C L+ T G + GPC+ A P S
Sbjct: 928 CPEANATKVCGSDGVTYGNECQLK-----TIACRQGLQISIQSLGPCQEAVAPSTHPTSA 982
Query: 165 HNVTGAQVGLSCEVRAVPTP 184
+VT GL +A+P P
Sbjct: 983 -SVTVTTPGLLLS-QALPAP 1000
Score = 36.2 bits (82), Expect = 0.032
Identities = 42/152 (27%), Positives = 50/152 (32%), Gaps = 33/152 (21%)
Query: 39 GPCRPEGCPAPAPCPAPGISALDECGCC---------------ARCLGAEGASCGGRAGG 83
G C C P P P G + C AR E A CG G
Sbjct: 616 GQCVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSG 675
Query: 84 RCGPG---LVCASQAAGAAPEGT--GLCVC------AQRGTVCGSDGRSYPSVCALRLRA 132
G Q G E + G CVC VCGSDG +Y + C L+
Sbjct: 676 SGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGSPVCGSDGVTYSTECELKKAR 735
Query: 133 RHTPRAHPGHLHKARDGPCE---FAPVVVVPP 161
+ R L+ A G C FAP+ V P
Sbjct: 736 CESQRG----LYVAAQGACRGPTFAPLPPVAP 763
Score = 33.5 bits (75), Expect = 0.21
Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 9/54 (16%)
Query: 82 GGRCGPGLVCASQAAGAAPEGTGLCVCAQR------GTVCGSDGRSYPSVCALR 129
G CG G VC A G G CVC + VCGSD +Y + C L+
Sbjct: 174 GMLCGFGAVCEPNAEGP---GRASCVCKKSPCPSVVAPVCGSDASTYSNECELQ 224
Score = 33.5 bits (75), Expect = 0.21
Identities = 41/158 (25%), Positives = 52/158 (32%), Gaps = 46/158 (29%)
Query: 35 RPKCG---PCRPEGCPAPAPCPAPGISALDECGCCARCLGA-EGASCGGRAGGRCGPG-- 88
R CG PC C + C C C A C GA EG CG + G PG
Sbjct: 239 RGPCGSRDPCSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCG--SDGADYPGEC 296
Query: 89 ----LVCASQ-------------AAGAAPEGTGLCVC-----------------AQRGTV 114
CA Q GA P+ + C A++ V
Sbjct: 297 QLLRRACARQENVFKKFDGPCDPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPV 356
Query: 115 CGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCE 152
CG DG +Y + C + + A L K R G C+
Sbjct: 357 CGDDGVTYENDCVM----GRSGAARGLLLQKVRSGQCQ 390
Score = 32.3 bits (72), Expect = 0.47
Identities = 32/112 (28%), Positives = 37/112 (33%), Gaps = 18/112 (16%)
Query: 37 KCG--PCRPEGCPAPAPCPAPGISALDECGCCARCLGAEGASCGGRAGGRCGPGLVCASQ 94
+CG PC P C APC C C G G +C C P +
Sbjct: 1547 ECGDHPCLPNPCHGGAPCQNLEAGRF-HCQCPP---GRVGPTCADEK-SPCQPNPCHGAA 1601
Query: 95 AAGAAPEGTGLCVC--AQRGTVC----GSDG-----RSYPSVCALRLRARHT 135
PEG C C + GT C G DG + L LR HT
Sbjct: 1602 PCRVLPEGGAQCECPLGREGTFCQTASGQDGSGPFLADFNGFSHLELRGLHT 1653
>gi|4505423 nephroblastoma overexpressed precursor [Homo sapiens]
Length = 357
Score = 50.1 bits (118), Expect = 2e-06
Identities = 34/89 (38%), Positives = 38/89 (42%), Gaps = 4/89 (4%)
Query: 37 KCGPCRPEGCPAPAPCPAPGISA-LDECGCCARCLGAEGASCGGRAGGRCGPGLVCASQA 95
+C P P CPA P APG+ A LD C CC C G SC GL C A
Sbjct: 34 RCPPQCPGRCPATPPTCAPGVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSA 93
Query: 96 AGAAPEGTGLCVCAQRGTVCGSDGRSYPS 124
+ TG+C A G C DG Y S
Sbjct: 94 DPS--NQTGICT-AVEGDNCVFDGVIYRS 119
>gi|4507923 WNT1 inducible signaling pathway protein 2 precursor
[Homo sapiens]
Length = 250
Score = 49.7 bits (117), Expect = 3e-06
Identities = 33/89 (37%), Positives = 39/89 (43%), Gaps = 11/89 (12%)
Query: 42 RPEGCPAPAPCPAP------GIS-ALDECGCCARCLGAEGASCGGRAGGRCGPGLVCASQ 94
R + CP P CP P G+ LD CGCC C G C GLVC
Sbjct: 22 RTQLCPTPCTCPWPPPRCPLGVPLVLDGCGCCRVCARRLGEPCDQLHVCDASQGLVC--- 78
Query: 95 AAGAAPEGTG-LCVCAQRGTVCGSDGRSY 122
GA P G G LC+ A+ + C +GR Y
Sbjct: 79 QPGAGPGGRGALCLLAEDDSSCEVNGRLY 107
>gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens]
Length = 1036
Score = 48.9 bits (115), Expect = 5e-06
Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 10/83 (12%)
Query: 11 LLLLLLPLLPPLSPSLGIRDVGGRRPKCGPCRPEGCPAPAPCPAPGISALDECGCCARCL 70
LL+ LL LL L+ S G R C PC C P CP + + CGCC C
Sbjct: 16 LLVSLLGLLLLLARS------GTRALVCLPCDESKCEEPRNCPGSIVQGV--CGCCYTCA 67
Query: 71 GAEGASCGGRAG--GRCGPGLVC 91
SCGG G G C GL C
Sbjct: 68 SQRNESCGGTFGIYGTCDRGLRC 90
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 48.1 bits (113), Expect = 8e-06
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 16/111 (14%)
Query: 152 EFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
E P + P+ V+G C+ P P +TW K K +Q E +
Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN-SQRFETIE------ 82
Query: 212 AVQVRGGPSDHEATAWILINPLRK-EDEGVYQCHAANMVGEAESHSTVTVL 261
D A A + I PLR DE VY+C A N VGE H+ +TVL
Sbjct: 83 --------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL 125
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 48.1 bits (113), Expect = 8e-06
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 16/111 (14%)
Query: 152 EFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
E P + P+ V+G C+ P P +TW K K +Q E +
Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN-SQRFETIE------ 82
Query: 212 AVQVRGGPSDHEATAWILINPLRK-EDEGVYQCHAANMVGEAESHSTVTVL 261
D A A + I PLR DE VY+C A N VGE H+ +TVL
Sbjct: 83 --------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL 125
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 48.1 bits (113), Expect = 8e-06
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 16/111 (14%)
Query: 152 EFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
E P + P+ V+G C+ P P +TW K K +Q E +
Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN-SQRFETIE------ 82
Query: 212 AVQVRGGPSDHEATAWILINPLRK-EDEGVYQCHAANMVGEAESHSTVTVL 261
D A A + I PLR DE VY+C A N VGE H+ +TVL
Sbjct: 83 --------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL 125
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 48.1 bits (113), Expect = 8e-06
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 16/111 (14%)
Query: 152 EFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
E P + P+ V+G C+ P P +TW K K +Q E +
Sbjct: 30 EEPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVN-SQRFETIE------ 82
Query: 212 AVQVRGGPSDHEATAWILINPLRK-EDEGVYQCHAANMVGEAESHSTVTVL 261
D A A + I PLR DE VY+C A N VGE H+ +TVL
Sbjct: 83 --------FDESAGAVLRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVL 125
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 48.1 bits (113), Expect = 8e-06
Identities = 61/230 (26%), Positives = 76/230 (33%), Gaps = 45/230 (19%)
Query: 45 GCPAPAPCPAPGISALDECGCCAR---CLGAEGASCGGRAGGRCGPGLVCASQAAGAAPE 101
G P PC P +A C R C G E G CGP C P
Sbjct: 278 GSVRPLPC-GPQEAACRNGHCIPRDYLCDGQEDCEDGSDELD-CGPPPPCEPNEF---PC 332
Query: 102 GTGLCV-----------CAQRGTVCGSDGRSYPSVCA-LRLRARHTPRAHPGHLHKARDG 149
G G C C R + VC + R T P H +
Sbjct: 333 GNGHCALKLWRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEES 392
Query: 150 PC-----EFA---PVVVVPPR-SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQA 200
C EF P VV PPR S+ G V +C VPTP+I WR
Sbjct: 393 DCPDRSDEFGCMPPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWR---------LN 443
Query: 201 LEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVG 250
+P H + V GG ++I +++ D+G Y C A N G
Sbjct: 444 WGHIP-SHPRVTVTSEGG------RGTLIIRDVKESDQGAYTCEAMNARG 486
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 19/110 (17%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P V V P G V L C VP+ ITWRK EG + + +IA
Sbjct: 1956 PRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRK-----EGGSLPPQARSERTDIAT- 2009
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLS 264
+LI + D G Y C A + G A++ V VL S
Sbjct: 2010 -------------LLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSAS 2046
Score = 33.9 bits (76), Expect = 0.16
Identities = 31/127 (24%), Positives = 45/127 (35%), Gaps = 35/127 (27%)
Query: 143 LHKARDGPCEFAPV------VVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPE 196
LH GP + PV + + P S H G + L+C V +TW K
Sbjct: 2135 LHGTHSGP-SYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHK------ 2187
Query: 197 GTQALEELPGDHVNIAVQVRGG--PSDHEATAWIL-INPLRKEDEGVYQCHAANMVGEAE 253
RGG P+ H+ +L ++ + D G Y CH G E
Sbjct: 2188 -------------------RGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLE 2228
Query: 254 SHSTVTV 260
+ VT+
Sbjct: 2229 ASVLVTI 2235
Score = 33.5 bits (75), Expect = 0.21
Identities = 25/94 (26%), Positives = 33/94 (35%), Gaps = 22/94 (23%)
Query: 167 VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATA 226
V G V C P P +TW KV G H+ + GG
Sbjct: 3501 VVGHAVEFECLALGDPKPQVTWSKV--------------GGHLRPGIVQSGGV------- 3539
Query: 227 WILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ I + D G Y+C A N G +SH + V
Sbjct: 3540 -VRIAHVELADAGQYRCTATNAAGTTQSHVLLLV 3572
Score = 31.2 bits (69), Expect = 1.0
Identities = 23/100 (23%), Positives = 37/100 (37%), Gaps = 22/100 (22%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P+ V G+ C PTP I+W K+ S LP P
Sbjct: 3581 PQEVRVPAGSAAVFPCIASGYPTPDISWSKLDGS---------LP-------------PD 3618
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+++ +R +D G Y C A N G+ ++ + + V
Sbjct: 3619 SRLENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658
Score = 30.0 bits (66), Expect = 2.3
Identities = 26/110 (23%), Positives = 42/110 (38%), Gaps = 28/110 (25%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
+P + + S V G + L+C V P +ITW K
Sbjct: 2629 SPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYK----------------------- 2665
Query: 214 QVRGG--PSDHEA-TAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
RGG PS H+ + + ++ + D G Y C A N + E+ ++V
Sbjct: 2666 --RGGSLPSRHQTHGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISV 2713
Score = 30.0 bits (66), Expect = 2.3
Identities = 26/110 (23%), Positives = 37/110 (33%), Gaps = 28/110 (25%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
AP + + P S G + L C V +TW K
Sbjct: 2826 APPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHK----------------------- 2862
Query: 214 QVRGG--PSDHEATAWIL-INPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
RGG P+ H+ +L +N + D G Y C G E+ VT+
Sbjct: 2863 --RGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTI 2910
Score = 29.3 bits (64), Expect = 4.0
Identities = 26/101 (25%), Positives = 39/101 (38%), Gaps = 22/101 (21%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
AP V + G L C P P I W K+ +SP LP H
Sbjct: 3211 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKL-RSP--------LPWQH----- 3256
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAES 254
++ G ++I + ++D G Y C+A + G AE+
Sbjct: 3257 RLEGDT--------LIIPRVAQQDSGQYICNATSPAGHAEA 3289
Score = 29.3 bits (64), Expect = 4.0
Identities = 28/109 (25%), Positives = 33/109 (30%), Gaps = 22/109 (20%)
Query: 152 EFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
E P P G V L C P W +V S LPG
Sbjct: 3296 ESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---------LPG----- 3341
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
R E A ED G Y+C N VG AE+ + + V
Sbjct: 3342 RATARNELLHFERAA--------PEDSGRYRCRVTNKVGSAEAFAQLLV 3382
Score = 28.9 bits (63), Expect = 5.2
Identities = 36/138 (26%), Positives = 46/138 (33%), Gaps = 26/138 (18%)
Query: 36 PKCGPCRP-------EGCPAPA---PC---PAPGISA----LDECG---CCARCLGAEGA 75
P+C C+P G P PC PA G +A LD G C A G G
Sbjct: 1185 PRCEQCQPGYYGDAQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGR 1244
Query: 76 SCGGRAGGRCG---PGLVCASQAAGAAPEGTGLCVCAQRGTVCGSDGRSYPSVCALRLRA 132
C A G G G C + P G C C +G+V + C ++
Sbjct: 1245 HCERCAPGYYGNPSQGQPCQRDSQVPGPIG---CNCDPQGSVSSQCDAAGQCQCKAQVEG 1301
Query: 133 RHTPRAHPGHLHKARDGP 150
P H H + P
Sbjct: 1302 LTCSHCRPHHFHLSASNP 1319
Score = 28.9 bits (63), Expect = 5.2
Identities = 26/104 (25%), Positives = 37/104 (35%), Gaps = 22/104 (21%)
Query: 157 VVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVR 216
V + S G + L+C V + ITW K S LP H + ++R
Sbjct: 2536 VRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGS---------LPSRHQIVGSRLR 2586
Query: 217 GGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
I + D G Y CH +N G E+ VT+
Sbjct: 2587 -------------IPQVTPADSGEYVCHVSNGAGSRETSLIVTI 2617
Score = 28.9 bits (63), Expect = 5.2
Identities = 26/105 (24%), Positives = 37/105 (35%), Gaps = 16/105 (15%)
Query: 156 VVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQV 215
V V+P V G V L C P W +++ +P + Q
Sbjct: 3114 VSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPAKLE--------------QR 3159
Query: 216 RGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
G D A + I+ + D G Y C A N +G A+ V V
Sbjct: 3160 TYGLMDSHAV--LQISSAKPSDAGTYVCLAQNALGTAQKQVEVIV 3202
Score = 28.1 bits (61), Expect = 8.8
Identities = 25/107 (23%), Positives = 39/107 (36%), Gaps = 21/107 (19%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
APVV + P + G C PTP + W T P G +LP
Sbjct: 1865 APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW---TGGPGG-----QLPA-----KA 1911
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
Q+ GG + + + D+ Y C A + G+ + + + V
Sbjct: 1912 QIHGG--------ILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHV 1950
>gi|134244585 putative neuronal cell adhesion molecule [Homo
sapiens]
Length = 814
Score = 48.1 bits (113), Expect = 8e-06
Identities = 39/137 (28%), Positives = 58/137 (42%), Gaps = 24/137 (17%)
Query: 125 VCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTP 184
VCA R G L P EF V P+S+ G +C+ + P P
Sbjct: 306 VCAANRPGTRVRRTAQGRL--VVQAPAEF----VQHPQSISRPAGTTAMFTCQAQGEPPP 359
Query: 185 VITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCH 244
+TW K Q L PG HV + ++ +T + I+ + EDE +YQC
Sbjct: 360 HVTWLK------NGQVLG--PGGHVRL--------KNNNST--LTISGIGPEDEAIYQCV 401
Query: 245 AANMVGEAESHSTVTVL 261
A N G +++ + +TVL
Sbjct: 402 AENSAGSSQASARLTVL 418
Score = 35.4 bits (80), Expect = 0.055
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 18/115 (15%)
Query: 159 VPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGG 218
V P++ G C++ +P P+ITW K + P T D+ + +G
Sbjct: 143 VHPQATVGEEGGVARFQCQIHGLPKPLITWEK-NRVPIDT--------DNERYTLLPKG- 192
Query: 219 PSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSFHFPA 273
+ I LR ED G++ C A+N+ SH + S ++ PA
Sbjct: 193 --------VLQITGLRAEDGGIFHCVASNIASIRISHGARLTVSGSGSGAYKEPA 239
Score = 32.0 bits (71), Expect = 0.61
Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 20/96 (20%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P ++V P ++ L C P P+++W ++ P G + ++ L
Sbjct: 238 PAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIGVEGIQVL---------- 287
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVG 250
T ++I+ + + GVY C AAN G
Sbjct: 288 ---------GTGNLIISDVTVQHSGVYVC-AANRPG 313
Score = 31.6 bits (70), Expect = 0.80
Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 19/95 (20%)
Query: 159 VPPRSVHNVTGAQVGLSCEVRAVPTPVITWRK-VTKSPEGTQALEELPGDHV--NIAVQV 215
V P V G + L C V P ITWRK + PE T + G + + ++
Sbjct: 46 VEPSDDVAVPGQPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLMIRHFRLEP 105
Query: 216 RGGPSDHEATAWILINPLRKEDEGVYQCHAANMVG 250
G PS DEG Y+C A N G
Sbjct: 106 GGSPS----------------DEGDYECVAQNRFG 124
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/119 (32%), Positives = 49/119 (41%), Gaps = 26/119 (21%)
Query: 156 VVVVPPR----SVHNVT--GAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
VV VPPR + H++T G L C VP P ITW K T + G H
Sbjct: 971 VVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSR-------GPHY 1023
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVG--EAESHSTVTVLDLSKY 266
N++ + +LI +D G Y C A N VG E +V L LSKY
Sbjct: 1024 NVSKE-----------GTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKY 1071
Score = 46.6 bits (109), Expect = 2e-05
Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 29/113 (25%)
Query: 150 PCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
P EF VVV V G+ V L CE R VP P+++W K P +Q+LE+
Sbjct: 3409 PVEFQNDVVV-------VRGSLVELPCEARGVPLPLVSWMK-DGEPLLSQSLEQ------ 3454
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
GPS + + + D G Y C A + GEA H +TV++
Sbjct: 3455 --------GPS-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 3492
Score = 45.8 bits (107), Expect = 4e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 19/109 (17%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
AP V + S H G +V +SC PTP I+W + +QAL+E HV
Sbjct: 607 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSR------ESQALQEDSRIHV---- 656
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
+A ++I + ED G Y C A N VG + T+ D
Sbjct: 657 ---------DAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD 696
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 18/90 (20%)
Query: 172 VGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILIN 231
+ L CE A P+P ITW K E ++ ++ LPG H + I
Sbjct: 2559 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH------------------GLQIL 2600
Query: 232 PLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+KED G Y C N +GEA + V VL
Sbjct: 2601 NAQKEDAGQYTCVVTNELGEAVKNYHVEVL 2630
Score = 42.7 bits (99), Expect = 3e-04
Identities = 36/123 (29%), Positives = 50/123 (40%), Gaps = 25/123 (20%)
Query: 153 FAPVVVVPP-------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELP 205
F V VPP +V V G+ + L+C+V VP P +TW K + P + A+
Sbjct: 3116 FTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK-DRMPVESSAVH--- 3171
Query: 206 GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSK 265
V RGG + ++ L+ G Y C A N EA V VL +
Sbjct: 3172 ------GVVSRGGR--------LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPR 3217
Query: 266 YRS 268
RS
Sbjct: 3218 IRS 3220
Score = 42.7 bits (99), Expect = 3e-04
Identities = 36/124 (29%), Positives = 48/124 (38%), Gaps = 19/124 (15%)
Query: 137 RAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPE 196
R G HK + +PVV P V V +V L CE +P P ITW+K +
Sbjct: 3930 RNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVA 3989
Query: 197 GTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHS 256
+ + LPG + IA H + ED G Y C A N G A +
Sbjct: 3990 TGVSTQVLPGGQLRIA---------HAS----------PEDAGNYLCIAKNSAGSAMGKT 4030
Query: 257 TVTV 260
+ V
Sbjct: 4031 RLVV 4034
Score = 42.0 bits (97), Expect = 6e-04
Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 25/112 (22%)
Query: 157 VVVPPR-------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
V VPPR V + + V L C+V A P P +TW K +++ + + LPG H
Sbjct: 2933 VQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT 2992
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+ + R D G+Y C A N G + ++VL
Sbjct: 2993 ------------------LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL 3026
Score = 42.0 bits (97), Expect = 6e-04
Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 19/107 (17%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
APV V P+ + +G V L C+ PTP I W + + ++ L LP
Sbjct: 4308 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP-------- 4359
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + W + + D G Y C A N++G A + + + V
Sbjct: 4360 ---------DGSLW--LENVETGDAGTYDCVAHNLLGSATARAFLVV 4395
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 25/117 (21%)
Query: 141 GHLHKARDGPCEFAPVVVVPPRSVHNVT---GAQVGLSCEVRAVPTPVITWRKVTKSPEG 197
GH K + APV P R H +T G LSCE R VP P I+WRK +G
Sbjct: 2148 GHSEKHYNLNVWVAPVF--PLRESHTLTVREGHPTSLSCECRGVPFPKISWRK-----DG 2200
Query: 198 TQALEELPGDHVNIAVQVRGGPSDHEATA--WILINPLRKEDEGVYQCHAANMVGEA 252
+ LPG+ G H + + + + EG Y C +N+VG +
Sbjct: 2201 ----QPLPGE---------GAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNS 2244
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/171 (26%), Positives = 72/171 (42%), Gaps = 32/171 (18%)
Query: 101 EGTGLCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVP 160
E G V A+ G + G+S + R +A HT R + A +F V+VP
Sbjct: 2293 ERDGQPVGAELGLQLQNQGQS---LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVP 2349
Query: 161 PRSVH------NVTGA---QVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
P + N+T A + L CE +P P I W + G + + PG+ +
Sbjct: 2350 PELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR------GEEPVS--PGEDTYL 2401
Query: 212 AVQVRGGPSDHEATAWIL-INPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
A W+L + +++D G+Y C A+N GEA + +V VL
Sbjct: 2402 L-----------AGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVL 2441
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/128 (26%), Positives = 48/128 (37%), Gaps = 28/128 (21%)
Query: 156 VVVVPP------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
VV VPP + G+ L C+ R P P ITW K + G +
Sbjct: 4033 VVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE---------- 4082
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSF 269
G + + +L+ L +D G Y C A N VG A +T+L L + +
Sbjct: 4083 --------GKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTL 4134
Query: 270 HFPAPDDR 277
P DR
Sbjct: 4135 ----PGDR 4138
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 20/90 (22%)
Query: 172 VGLSCEVRAVPTPVITWRK-VTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILI 230
V L CE R VPTP ITW K P T+ V RGG + +
Sbjct: 1520 VQLLCEARGVPTPNITWFKDGALLPTSTK------------VVYTRGGRQ-------LQL 1560
Query: 231 NPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ D GVY C A+N VG AE + + V
Sbjct: 1561 GRAQSSDAGVYTCKASNAVGAAEKATRLDV 1590
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 28/107 (26%)
Query: 161 PRSVHNVTGAQVG----LSCEVRAVPTPVITWRKVTKS---PEGTQALEELPGDHVNIAV 213
PR + +VG LSCE A+P P +TW K + + TQAL
Sbjct: 3035 PRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL------------ 3082
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
RGG + I + D+G+Y C +N+ GEA T+TV
Sbjct: 3083 --RGGQR-------LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV 3120
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/109 (28%), Positives = 44/109 (40%), Gaps = 24/109 (22%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN---I 211
P ++ +V V V L C+ A+P PV++W K + LE PG H++
Sbjct: 2071 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWK------DGRPLEPRPGVHLSADKA 2124
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+QV A W D G Y C A N G +E H + V
Sbjct: 2125 LLQV------DRADVW---------DAGHYTCEALNQAGHSEKHYNLNV 2158
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 24/118 (20%)
Query: 152 EFAPVVVVPPR--------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEE 203
+F V+V PR H + G +V L CE P P + W K +G+ ++
Sbjct: 3207 DFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLK-----DGSPLGQD 3261
Query: 204 LPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+ G H+ + GG +++ LR D G Y C A N GE TV VL
Sbjct: 3262 M-GPHLRFYLD--GGS--------LVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVL 3308
Score = 39.7 bits (91), Expect = 0.003
Identities = 27/97 (27%), Positives = 37/97 (38%), Gaps = 17/97 (17%)
Query: 164 VHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHE 223
+ V G L C R P P +TWRK S + L PG +AV G
Sbjct: 1216 LERVAGENASLPCPARGTPKPQVTWRKGPSS----EPLHGQPG----VAVLEEGS----- 1262
Query: 224 ATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + + D G Y+C A N VG + + V
Sbjct: 1263 ----LFLASVSPADSGDYECQATNEVGSTSRRAKLVV 1295
Score = 39.3 bits (90), Expect = 0.004
Identities = 26/107 (24%), Positives = 41/107 (38%), Gaps = 12/107 (11%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
AP + PR V G L+C P P +TWR+ P G +
Sbjct: 785 APQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLR------------LG 832
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
RG S + + + ED+ Y C A N+ G+ ++ + + V
Sbjct: 833 AGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 879
Score = 37.7 bits (86), Expect = 0.011
Identities = 28/100 (28%), Positives = 37/100 (37%), Gaps = 21/100 (21%)
Query: 155 PVVVVPPRSVHNV-TGAQVGLSCEVRAVPTPVITWRKVTK--SPEGTQALEELPGDHVNI 211
P + +PP V V L+C P+P + W K SP GT L+ PG V
Sbjct: 1977 PRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-- 2034
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGE 251
+ + R D G Y C A + VGE
Sbjct: 2035 ----------------LTLASARASDSGRYSCVAVSAVGE 2058
Score = 36.2 bits (82), Expect = 0.032
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 36/121 (29%)
Query: 145 KARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEEL 204
+AR G E+ +V P ++ C+ A+P P +TW + E+
Sbjct: 2751 EARGGVTEYREIVENNPAYLY----------CDTNAIPPPDLTWYR-----------EDQ 2789
Query: 205 P---GDHVNIAVQVRGGPSDHEATAWILINPL-RKEDEGVYQCHAANMVGEAESHSTVTV 260
P GD V++ ++GG +L PL R E+ G Y C A+N VGE H + V
Sbjct: 2790 PLSAGDEVSV---LQGGR--------VLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 2838
Query: 261 L 261
L
Sbjct: 2839 L 2839
Score = 35.0 bits (79), Expect = 0.072
Identities = 31/118 (26%), Positives = 40/118 (33%), Gaps = 21/118 (17%)
Query: 154 APVVVVPPRSVHNVTG---AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN 210
AP +V PR V G Q+ L C V A P P ITW +
Sbjct: 3578 APPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR------------------DG 3619
Query: 211 IAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRS 268
I +Q E ++ + L D G Y C A N G V + + RS
Sbjct: 3620 IVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRS 3677
Score = 33.9 bits (76), Expect = 0.16
Identities = 33/129 (25%), Positives = 50/129 (38%), Gaps = 32/129 (24%)
Query: 144 HKARDGPCEFAPVVVVPPRSVHN---------VTGAQVGLSCEVRAVPTPVITWRKVTKS 194
++A + F+ V+VPP S+ N + G L C V P P +TW K +
Sbjct: 2427 NEAGEARRNFSVEVLVPP-SIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRP 2485
Query: 195 PEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKE--DEGVYQCHAANMVGEA 252
+ G + H + +L+ L+ G Y C AAN VGE
Sbjct: 2486 --------------------LARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK 2525
Query: 253 ESHSTVTVL 261
H ++VL
Sbjct: 2526 TKHFQLSVL 2534
Score = 33.9 bits (76), Expect = 0.16
Identities = 38/144 (26%), Positives = 54/144 (37%), Gaps = 28/144 (19%)
Query: 110 QRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTG 169
QR V D +Y VC R T H+ +A E +V P G
Sbjct: 4183 QRAAVSREDSGTY--VCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEP-------VG 4233
Query: 170 AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWIL 229
+ L C VR P P I W K + LP ++ Q++ G +
Sbjct: 4234 GSIQLDCVVRGDPVPDIHWIK-----------DGLPLRGSHLRHQLQNGS--------LT 4274
Query: 230 INPLRKEDEGVYQCHAANMVGEAE 253
I+ ++D G YQC A N +G A+
Sbjct: 4275 IHRTERDDAGRYQCLAENEMGVAK 4298
Score = 33.5 bits (75), Expect = 0.21
Identities = 26/106 (24%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P+ V + V + + L CE AVP P I W K + + L+ L +
Sbjct: 2640 PLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL----- 2694
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ I P + D G Y C A N+ GE + V +
Sbjct: 2695 -------------LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLI 2727
Score = 33.5 bits (75), Expect = 0.21
Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 20/106 (18%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
PV P G ++ L C R PTP I W V P
Sbjct: 4129 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWT-VNDRP------------------- 4168
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
V G S+ + + + + +ED G Y C A N VG ++ S V V
Sbjct: 4169 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHV 4214
Score = 32.7 bits (73), Expect = 0.36
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 26/123 (21%)
Query: 146 ARDGPCEFAPVVVVPPR--------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEG 197
A + +++ V VPP+ V + G + L C+ P P I W +
Sbjct: 1673 AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL------QN 1726
Query: 198 TQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHST 257
+ EEL G V +A Q G + H I+ + + G++ C A N G A +
Sbjct: 1727 GRPAEELAG--VQVASQ---GTTLH-------IDHVELDHSGLFACQATNEAGTAGAEVE 1774
Query: 258 VTV 260
V+V
Sbjct: 1775 VSV 1777
Score = 32.7 bits (73), Expect = 0.36
Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 18/108 (16%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P + P +V+ L C+ VP P+++WRK + +P D + +
Sbjct: 3673 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRK-----------DRVPLDPRSPRFE 3721
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
+ S + I P+ +D G Y C A+N G + VL+
Sbjct: 3722 ILPEGS-------LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE 3762
Score = 32.0 bits (71), Expect = 0.61
Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 27/109 (24%)
Query: 152 EFAPVVVVPP--------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEE 203
+F +V+ PP + V + GA V L C VPTP + W K + P
Sbjct: 1398 DFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK-DRQP-------V 1449
Query: 204 LP-GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGE 251
LP G H+ + E + I DEG YQC A + G+
Sbjct: 1450 LPGGPHLQV----------QEDGQVLRITGSHVGDEGRYQCVAFSPAGQ 1488
Score = 31.6 bits (70), Expect = 0.80
Identities = 29/108 (26%), Positives = 42/108 (38%), Gaps = 24/108 (22%)
Query: 152 EFAPVVVVPPRSVHN------VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELP 205
E A V+VPP + A V L C VP P ++W K G Q +
Sbjct: 1877 EVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFK------GHQPVSSWM 1930
Query: 206 GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAE 253
G V++ +V + I + D G Y+C A+N+ G E
Sbjct: 1931 GVTVSVDGRV------------LRIEQAQLSDAGSYRCVASNVAGSTE 1966
Score = 30.8 bits (68), Expect = 1.4
Identities = 26/102 (25%), Positives = 35/102 (34%), Gaps = 18/102 (17%)
Query: 160 PPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGP 219
PP V V L C P P +TW + P G + +L G
Sbjct: 2264 PPTQVSVVQDGVATLECNATGKPPPTVTWER-DGQPVGAELGLQLQNQ----------GQ 2312
Query: 220 SDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
S H + + G Y C A N+ G AE ++VL
Sbjct: 2313 SLH-------VERAQAAHTGRYSCVAENLAGRAERKFELSVL 2347
Score = 30.4 bits (67), Expect = 1.8
Identities = 28/118 (23%), Positives = 46/118 (38%), Gaps = 31/118 (26%)
Query: 165 HNVTGAQVGL-SCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHE 223
HN G L + V PT + + +G+ L PG+ V + VRG P H
Sbjct: 3293 HNPAGEDARLHTVNVLVPPT-------IKQGADGSGTLVSRPGELVTMVCPVRGSPPIH- 3344
Query: 224 ATAW---------------------ILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+W + I+ ++ D G++ C AA+ G A+ + T+ V
Sbjct: 3345 -VSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQV 3401
Score = 30.0 bits (66), Expect = 2.3
Identities = 50/229 (21%), Positives = 71/229 (31%), Gaps = 48/229 (20%)
Query: 44 EGCPAPAPC-----PAPGISALDECGCCARC-----LGAEGASCGGRAGGRCGPGLVC-A 92
EG PA PC PAP I+ E + EG + + VC A
Sbjct: 989 EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTA 1048
Query: 93 SQAAGAAPEGTGLCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCE 152
+ G + + L V R + Y + + LR GH P
Sbjct: 1049 TNTVGFSSQEMRLSV--NRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAG 1106
Query: 153 FA-----------PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQAL 201
A P V PR + + G + L+C P P ++W K
Sbjct: 1107 SASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSK----------- 1155
Query: 202 EELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVG 250
+ +Q RG A +R D G Y+C A+N G
Sbjct: 1156 -------DGVVLQGRGPQGSVHFAA------IRTSDAGRYRCEASNSAG 1191
Score = 30.0 bits (66), Expect = 2.3
Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 25/100 (25%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P + GA + L C+ + P P ITW K QAL L +
Sbjct: 3502 PTELSLTPGAPMELLCDAQGTPQPNITWHK------DGQALTRL--------------EN 3541
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ AT LR D G+Y C A + G E V V
Sbjct: 3542 NSRAT-----RVLRVRDAGLYTCLAESPAGAIEKSFRVRV 3576
Score = 29.3 bits (64), Expect = 4.0
Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 29/96 (30%)
Query: 169 GAQVGLSCEVRAVPTPVITWRK----VTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEA 224
G + L CE VP P + W + + +PEG+ +
Sbjct: 712 GEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGS-------------------------S 746
Query: 225 TAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + I ++ D G Y C A N +G+A + + V
Sbjct: 747 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 29.3 bits (64), Expect = 4.0
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 5/41 (12%)
Query: 226 AWILINPLRKE-----DEGVYQCHAANMVGEAESHSTVTVL 261
A+ L PL+ E DEG+Y C A N+ GE++ + VL
Sbjct: 1843 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVL 1883
Score = 28.5 bits (62), Expect = 6.8
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 20/101 (19%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITW-RKVTKSPEGTQALEELPGDHVNIAVQVRGGP 219
P V V G V L C R P+P ++W + E ++ E G + +
Sbjct: 1603 PYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRL-------E 1655
Query: 220 SDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
S EA++ G+Y C A++ GEA +V V
Sbjct: 1656 SPGEASS------------GLYSCVASSPAGEAVLQYSVEV 1684
Score = 28.1 bits (61), Expect = 8.8
Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 16/106 (15%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P + P ++ L CE P P++ W K G ++ +Q
Sbjct: 3764 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK--------------DGQKLDFRLQ 3809
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+G + A +L P +D ++C +N VGEA VTV
Sbjct: 3810 -QGAYRLLPSNALLLTAP-GPQDSAQFECVVSNEVGEAHRLYQVTV 3853
Score = 28.1 bits (61), Expect = 8.8
Identities = 28/110 (25%), Positives = 37/110 (33%), Gaps = 24/110 (21%)
Query: 157 VVVPPRSVHNVTG------AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN 210
V VPP + T A V L+C +P P ++W K G Q
Sbjct: 3853 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKA-----GAQ----------- 3896
Query: 211 IAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ RG + + I G Y C A N G A H +TV
Sbjct: 3897 --LGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 3944
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 46.6 bits (109), Expect = 2e-05
Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 29/113 (25%)
Query: 150 PCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
P EF VVV V G+ V L CE R VP P+++W K P +Q+LE+
Sbjct: 2218 PVEFQNDVVV-------VRGSLVELPCEARGVPLPLVSWMK-DGEPLLSQSLEQ------ 2263
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
GPS + + + D G Y C A + GEA H +TV++
Sbjct: 2264 --------GPS-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 2301
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 18/90 (20%)
Query: 172 VGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILIN 231
+ L CE A P+P ITW K E ++ ++ LPG H + I
Sbjct: 1368 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH------------------GLQIL 1409
Query: 232 PLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+KED G Y C N +GEA + V VL
Sbjct: 1410 NAQKEDAGQYTCVVTNELGEAVKNYHVEVL 1439
Score = 42.7 bits (99), Expect = 3e-04
Identities = 36/123 (29%), Positives = 50/123 (40%), Gaps = 25/123 (20%)
Query: 153 FAPVVVVPP-------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELP 205
F V VPP +V V G+ + L+C+V VP P +TW K + P + A+
Sbjct: 1925 FTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK-DRMPVESSAVH--- 1980
Query: 206 GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSK 265
V RGG + ++ L+ G Y C A N EA V VL +
Sbjct: 1981 ------GVVSRGGR--------LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPR 2026
Query: 266 YRS 268
RS
Sbjct: 2027 IRS 2029
Score = 42.7 bits (99), Expect = 3e-04
Identities = 36/124 (29%), Positives = 48/124 (38%), Gaps = 19/124 (15%)
Query: 137 RAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPE 196
R G HK + +PVV P V V +V L CE +P P ITW+K +
Sbjct: 2739 RNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVA 2798
Query: 197 GTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHS 256
+ + LPG + IA H + ED G Y C A N G A +
Sbjct: 2799 TGVSTQVLPGGQLRIA---------HAS----------PEDAGNYLCIAKNSAGSAMGKT 2839
Query: 257 TVTV 260
+ V
Sbjct: 2840 RLVV 2843
Score = 42.0 bits (97), Expect = 6e-04
Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 25/112 (22%)
Query: 157 VVVPPR-------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
V VPPR V + + V L C+V A P P +TW K +++ + + LPG H
Sbjct: 1742 VQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT 1801
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+ + R D G+Y C A N G + ++VL
Sbjct: 1802 ------------------LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL 1835
Score = 42.0 bits (97), Expect = 6e-04
Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 19/107 (17%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
APV V P+ + +G V L C+ PTP I W + + ++ L LP
Sbjct: 3117 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP-------- 3168
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + W + + D G Y C A N++G A + + + V
Sbjct: 3169 ---------DGSLW--LENVETGDAGTYDCVAHNLLGSATARAFLVV 3204
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/171 (26%), Positives = 72/171 (42%), Gaps = 32/171 (18%)
Query: 101 EGTGLCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVP 160
E G V A+ G + G+S + R +A HT R + A +F V+VP
Sbjct: 1102 ERDGQPVGAELGLQLQNQGQS---LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVP 1158
Query: 161 PRSVH------NVTGA---QVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
P + N+T A + L CE +P P I W + G + + PG+ +
Sbjct: 1159 PELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR------GEEPVS--PGEDTYL 1210
Query: 212 AVQVRGGPSDHEATAWIL-INPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
A W+L + +++D G+Y C A+N GEA + +V VL
Sbjct: 1211 L-----------AGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVL 1250
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/128 (26%), Positives = 48/128 (37%), Gaps = 28/128 (21%)
Query: 156 VVVVPP------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
VV VPP + G+ L C+ R P P ITW K + G +
Sbjct: 2842 VVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE---------- 2891
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSF 269
G + + +L+ L +D G Y C A N VG A +T+L L + +
Sbjct: 2892 --------GKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTL 2943
Query: 270 HFPAPDDR 277
P DR
Sbjct: 2944 ----PGDR 2947
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 20/90 (22%)
Query: 172 VGLSCEVRAVPTPVITWRK-VTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILI 230
V L CE R VPTP ITW K P T+ V RGG + +
Sbjct: 329 VQLLCEARGVPTPNITWFKDGALLPTSTK------------VVYTRGGRQ-------LQL 369
Query: 231 NPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ D GVY C A+N VG AE + + V
Sbjct: 370 GRAQSSDAGVYTCKASNAVGAAEKATRLDV 399
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 23/100 (23%)
Query: 158 VVPPRSVHNVT---GAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
V P R H +T G LSCE R VP P I+WRK +G + LPG+
Sbjct: 972 VFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRK-----DG----QPLPGE------- 1015
Query: 215 VRGGPSDHEATA--WILINPLRKEDEGVYQCHAANMVGEA 252
G H + + + + EG Y C +N+VG +
Sbjct: 1016 --GAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNS 1053
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 28/107 (26%)
Query: 161 PRSVHNVTGAQVG----LSCEVRAVPTPVITWRKVTKS---PEGTQALEELPGDHVNIAV 213
PR + +VG LSCE A+P P +TW K + + TQAL
Sbjct: 1844 PRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL------------ 1891
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
RGG + I + D+G+Y C +N+ GEA T+TV
Sbjct: 1892 --RGGQR-------LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV 1929
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/109 (28%), Positives = 44/109 (40%), Gaps = 24/109 (22%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN---I 211
P ++ +V V V L C+ A+P PV++W K + LE PG H++
Sbjct: 880 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWK------DGRPLEPRPGVHLSADKA 933
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+QV A W D G Y C A N G +E H + V
Sbjct: 934 LLQV------DRADVW---------DAGHYTCEALNQAGRSEKHYNLNV 967
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 24/118 (20%)
Query: 152 EFAPVVVVPPR--------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEE 203
+F V+V PR H + G +V L CE P P + W K +G+ ++
Sbjct: 2016 DFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLK-----DGSPLGQD 2070
Query: 204 LPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+ G H+ + GG +++ LR D G Y C A N GE TV VL
Sbjct: 2071 M-GPHLRFYLD--GGS--------LVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVL 2117
Score = 37.7 bits (86), Expect = 0.011
Identities = 28/100 (28%), Positives = 37/100 (37%), Gaps = 21/100 (21%)
Query: 155 PVVVVPPRSVHNV-TGAQVGLSCEVRAVPTPVITWRKVTK--SPEGTQALEELPGDHVNI 211
P + +PP V V L+C P+P + W K SP GT L+ PG V
Sbjct: 786 PRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-- 843
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGE 251
+ + R D G Y C A + VGE
Sbjct: 844 ----------------LTLASARASDSGRYSCVAVSAVGE 867
Score = 36.2 bits (82), Expect = 0.032
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 36/121 (29%)
Query: 145 KARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEEL 204
+AR G E+ +V P ++ C+ A+P P +TW + E+
Sbjct: 1560 EARGGVTEYREIVENNPAYLY----------CDTNAIPPPDLTWYR-----------EDQ 1598
Query: 205 P---GDHVNIAVQVRGGPSDHEATAWILINPL-RKEDEGVYQCHAANMVGEAESHSTVTV 260
P GD V++ ++GG +L PL R E+ G Y C A+N VGE H + V
Sbjct: 1599 PLSAGDEVSV---LQGGR--------VLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 1647
Query: 261 L 261
L
Sbjct: 1648 L 1648
Score = 35.0 bits (79), Expect = 0.072
Identities = 31/118 (26%), Positives = 40/118 (33%), Gaps = 21/118 (17%)
Query: 154 APVVVVPPRSVHNVTG---AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN 210
AP +V PR V G Q+ L C V A P P ITW +
Sbjct: 2387 APPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR------------------DG 2428
Query: 211 IAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRS 268
I +Q E ++ + L D G Y C A N G V + + RS
Sbjct: 2429 IVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRS 2486
Score = 33.9 bits (76), Expect = 0.16
Identities = 33/129 (25%), Positives = 50/129 (38%), Gaps = 32/129 (24%)
Query: 144 HKARDGPCEFAPVVVVPPRSVHN---------VTGAQVGLSCEVRAVPTPVITWRKVTKS 194
++A + F+ V+VPP S+ N + G L C V P P +TW K +
Sbjct: 1236 NEAGEARRNFSVEVLVPP-SIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRP 1294
Query: 195 PEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKE--DEGVYQCHAANMVGEA 252
+ G + H + +L+ L+ G Y C AAN VGE
Sbjct: 1295 --------------------LARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK 1334
Query: 253 ESHSTVTVL 261
H ++VL
Sbjct: 1335 TKHFQLSVL 1343
Score = 33.9 bits (76), Expect = 0.16
Identities = 38/144 (26%), Positives = 54/144 (37%), Gaps = 28/144 (19%)
Query: 110 QRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTG 169
QR V D +Y VC R T H+ +A E +V P G
Sbjct: 2992 QRAAVSREDSGTY--VCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEP-------VG 3042
Query: 170 AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWIL 229
+ L C VR P P I W K + LP ++ Q++ G +
Sbjct: 3043 GSIQLDCVVRGDPVPDIHWIK-----------DGLPLRGSHLRHQLQNGS--------LT 3083
Query: 230 INPLRKEDEGVYQCHAANMVGEAE 253
I+ ++D G YQC A N +G A+
Sbjct: 3084 IHRTERDDAGRYQCLAENEMGVAK 3107
Score = 33.5 bits (75), Expect = 0.21
Identities = 26/106 (24%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P+ V + V + + L CE AVP P I W K + + L+ L +
Sbjct: 1449 PLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL----- 1503
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ I P + D G Y C A N+ GE + V +
Sbjct: 1504 -------------LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLI 1536
Score = 33.5 bits (75), Expect = 0.21
Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 20/106 (18%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
PV P G ++ L C R PTP I W V P
Sbjct: 2938 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWT-VNDRP------------------- 2977
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
V G S+ + + + + +ED G Y C A N VG ++ S V V
Sbjct: 2978 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHV 3023
Score = 32.7 bits (73), Expect = 0.36
Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 18/92 (19%)
Query: 169 GAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWI 228
G + G C P P +TWRK S + L PG +AV G +
Sbjct: 18 GLEAG-GCGTHGTPKPQVTWRKGPSS----EPLHGQPG----VAVLEEGS---------L 59
Query: 229 LINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + D G Y+C A N VG + + V
Sbjct: 60 FLASVSPADSGDYECQATNEVGSTSRRAKLVV 91
Score = 32.7 bits (73), Expect = 0.36
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 26/123 (21%)
Query: 146 ARDGPCEFAPVVVVPPR--------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEG 197
A + +++ V VPP+ V + G + L C+ P P I W +
Sbjct: 482 AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL------QN 535
Query: 198 TQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHST 257
+ EEL G V +A Q G + H I+ + + G++ C A N G A +
Sbjct: 536 GRPAEELAG--VQVASQ---GTTLH-------IDHVELDHSGLFACQATNEAGTAGAEVE 583
Query: 258 VTV 260
V+V
Sbjct: 584 VSV 586
Score = 32.7 bits (73), Expect = 0.36
Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 18/108 (16%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P + P +V+ L C+ VP P+++WRK + +P D + +
Sbjct: 2482 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRK-----------DRVPLDPRSPRFE 2530
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
+ S + I P+ +D G Y C A+N G + VL+
Sbjct: 2531 ILPEGS-------LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE 2571
Score = 31.6 bits (70), Expect = 0.80
Identities = 29/108 (26%), Positives = 42/108 (38%), Gaps = 24/108 (22%)
Query: 152 EFAPVVVVPPRSVHN------VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELP 205
E A V+VPP + A V L C VP P ++W K G Q +
Sbjct: 686 EVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFK------GHQPVSSWM 739
Query: 206 GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAE 253
G V++ +V + I + D G Y+C A+N+ G E
Sbjct: 740 GVTVSVDGRV------------LRIEQAQLSDAGSYRCVASNVAGSTE 775
Score = 30.8 bits (68), Expect = 1.4
Identities = 26/102 (25%), Positives = 35/102 (34%), Gaps = 18/102 (17%)
Query: 160 PPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGP 219
PP V V L C P P +TW + P G + +L G
Sbjct: 1073 PPTQVSVVQDGVATLECNATGKPPPTVTWER-DGQPVGAELGLQLQNQ----------GQ 1121
Query: 220 SDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
S H + + G Y C A N+ G AE ++VL
Sbjct: 1122 SLH-------VERAQAAHTGRYSCVAENLAGRAERKFELSVL 1156
Score = 30.4 bits (67), Expect = 1.8
Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 19/91 (20%)
Query: 162 RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELP-GDHVNIAVQVRGGPS 220
+ V + GA V L C VPTP + W K + P LP G H+ +
Sbjct: 225 QEVLGLAGADVELQCWTSGVPTPQVEWTK-DRQP-------VLPGGPHLQV--------- 267
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGE 251
E + I DEG YQC A + G+
Sbjct: 268 -QEDGQVLRITGSHVGDEGRYQCVAFSPAGQ 297
Score = 30.4 bits (67), Expect = 1.8
Identities = 28/118 (23%), Positives = 46/118 (38%), Gaps = 31/118 (26%)
Query: 165 HNVTGAQVGL-SCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHE 223
HN G L + V PT + + +G+ L PG+ V + VRG P H
Sbjct: 2102 HNPAGEDARLHTVNVLVPPT-------IKQGADGSGTLVSRPGELVTMVCPVRGSPPIH- 2153
Query: 224 ATAW---------------------ILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+W + I+ ++ D G++ C AA+ G A+ + T+ V
Sbjct: 2154 -VSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQV 2210
Score = 30.0 bits (66), Expect = 2.3
Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 25/100 (25%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P + GA + L C+ + P P ITW K QAL L +
Sbjct: 2311 PTELSLTPGAPMELLCDAQGTPQPNITWHK------DGQALTRL--------------EN 2350
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ AT LR D G+Y C A + G E V V
Sbjct: 2351 NSRAT-----RVLRVRDAGLYTCLAESPAGAIEKSFRVRV 2385
Score = 29.3 bits (64), Expect = 4.0
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 5/41 (12%)
Query: 226 AWILINPLRKE-----DEGVYQCHAANMVGEAESHSTVTVL 261
A+ L PL+ E DEG+Y C A N+ GE++ + VL
Sbjct: 652 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVL 692
Score = 28.5 bits (62), Expect = 6.8
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 20/101 (19%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITW-RKVTKSPEGTQALEELPGDHVNIAVQVRGGP 219
P V V G V L C R P+P ++W + E ++ E G + +
Sbjct: 412 PYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRL-------E 464
Query: 220 SDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
S EA++ G+Y C A++ GEA +V V
Sbjct: 465 SPGEASS------------GLYSCVASSPAGEAVLQYSVEV 493
Score = 28.1 bits (61), Expect = 8.8
Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 16/106 (15%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P + P ++ L CE P P++ W K G ++ +Q
Sbjct: 2573 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK--------------DGQKLDFRLQ 2618
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+G + A +L P +D ++C +N VGEA VTV
Sbjct: 2619 -QGAYRLLPSNALLLTAP-GPQDSAQFECVVSNEVGEAHRLYQVTV 2662
Score = 28.1 bits (61), Expect = 8.8
Identities = 28/110 (25%), Positives = 37/110 (33%), Gaps = 24/110 (21%)
Query: 157 VVVPPRSVHNVTG------AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN 210
V VPP + T A V L+C +P P ++W K G Q
Sbjct: 2662 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKA-----GAQ----------- 2705
Query: 211 IAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ RG + + I G Y C A N G A H +TV
Sbjct: 2706 --LGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 2753
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 46.6 bits (109), Expect = 2e-05
Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 29/113 (25%)
Query: 150 PCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
P EF VVV V G+ V L CE R VP P+++W K P +Q+LE+
Sbjct: 2127 PVEFQNDVVV-------VRGSLVELPCEARGVPLPLVSWMK-DGEPLLSQSLEQ------ 2172
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
GPS + + + D G Y C A + GEA H +TV++
Sbjct: 2173 --------GPS-------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 2210
Score = 43.1 bits (100), Expect = 3e-04
Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 18/90 (20%)
Query: 172 VGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILIN 231
+ L CE A P+P ITW K E ++ ++ LPG H + I
Sbjct: 1277 ISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTH------------------GLQIL 1318
Query: 232 PLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+KED G Y C N +GEA + V VL
Sbjct: 1319 NAQKEDAGQYTCVVTNELGEAVKNYHVEVL 1348
Score = 42.7 bits (99), Expect = 3e-04
Identities = 36/123 (29%), Positives = 50/123 (40%), Gaps = 25/123 (20%)
Query: 153 FAPVVVVPP-------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELP 205
F V VPP +V V G+ + L+C+V VP P +TW K + P + A+
Sbjct: 1834 FTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLK-DRMPVESSAVH--- 1889
Query: 206 GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSK 265
V RGG + ++ L+ G Y C A N EA V VL +
Sbjct: 1890 ------GVVSRGGR--------LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAPR 1935
Query: 266 YRS 268
RS
Sbjct: 1936 IRS 1938
Score = 42.7 bits (99), Expect = 3e-04
Identities = 36/124 (29%), Positives = 48/124 (38%), Gaps = 19/124 (15%)
Query: 137 RAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPE 196
R G HK + +PVV P V V +V L CE +P P ITW+K +
Sbjct: 2648 RNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVA 2707
Query: 197 GTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHS 256
+ + LPG + IA H + ED G Y C A N G A +
Sbjct: 2708 TGVSTQVLPGGQLRIA---------HAS----------PEDAGNYLCIAKNSAGSAMGKT 2748
Query: 257 TVTV 260
+ V
Sbjct: 2749 RLVV 2752
Score = 42.0 bits (97), Expect = 6e-04
Identities = 30/112 (26%), Positives = 45/112 (40%), Gaps = 25/112 (22%)
Query: 157 VVVPPR-------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
V VPPR V + + V L C+V A P P +TW K +++ + + LPG H
Sbjct: 1651 VQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHT 1710
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+ + R D G+Y C A N G + ++VL
Sbjct: 1711 ------------------LQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVL 1744
Score = 42.0 bits (97), Expect = 6e-04
Identities = 27/107 (25%), Positives = 44/107 (41%), Gaps = 19/107 (17%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
APV V P+ + +G V L C+ PTP I W + + ++ L LP
Sbjct: 3026 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLP-------- 3077
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + W + + D G Y C A N++G A + + + V
Sbjct: 3078 ---------DGSLW--LENVETGDAGTYDCVAHNLLGSATARAFLVV 3113
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/171 (26%), Positives = 72/171 (42%), Gaps = 32/171 (18%)
Query: 101 EGTGLCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVP 160
E G V A+ G + G+S + R +A HT R + A +F V+VP
Sbjct: 1011 ERDGQPVGAELGLQLQNQGQS---LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVP 1067
Query: 161 PRSVH------NVTGA---QVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNI 211
P + N+T A + L CE +P P I W + G + + PG+ +
Sbjct: 1068 PELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR------GEEPVS--PGEDTYL 1119
Query: 212 AVQVRGGPSDHEATAWIL-INPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
A W+L + +++D G+Y C A+N GEA + +V VL
Sbjct: 1120 L-----------AGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVL 1159
Score = 41.2 bits (95), Expect = 0.001
Identities = 34/128 (26%), Positives = 48/128 (37%), Gaps = 28/128 (21%)
Query: 156 VVVVPP------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHV 209
VV VPP + G+ L C+ R P P ITW K + G +
Sbjct: 2751 VVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAE---------- 2800
Query: 210 NIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSF 269
G + + +L+ L +D G Y C A N VG A +T+L L + +
Sbjct: 2801 --------GKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTL 2852
Query: 270 HFPAPDDR 277
P DR
Sbjct: 2853 ----PGDR 2856
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/90 (34%), Positives = 38/90 (42%), Gaps = 20/90 (22%)
Query: 172 VGLSCEVRAVPTPVITWRK-VTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILI 230
V L CE R VPTP ITW K P T+ V RGG + +
Sbjct: 238 VQLLCEARGVPTPNITWFKDGALLPTSTK------------VVYTRGGRQ-------LQL 278
Query: 231 NPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ D GVY C A+N VG AE + + V
Sbjct: 279 GRAQSSDAGVYTCKASNAVGAAEKATRLDV 308
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/117 (30%), Positives = 49/117 (41%), Gaps = 25/117 (21%)
Query: 141 GHLHKARDGPCEFAPVVVVPPRSVHNVT---GAQVGLSCEVRAVPTPVITWRKVTKSPEG 197
GH K + APV P R H +T G LSCE R VP P I+WRK +G
Sbjct: 866 GHSEKHYNLNVWVAPVF--PLRESHTLTVREGHPTRLSCECRGVPFPKISWRK-----DG 918
Query: 198 TQALEELPGDHVNIAVQVRGGPSDHEATA--WILINPLRKEDEGVYQCHAANMVGEA 252
+ LPG+ G H + + + + EG Y C +N+VG +
Sbjct: 919 ----QPLPGE---------GAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNS 962
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 28/107 (26%)
Query: 161 PRSVHNVTGAQVG----LSCEVRAVPTPVITWRKVTKS---PEGTQALEELPGDHVNIAV 213
PR + +VG LSCE A+P P +TW K + + TQAL
Sbjct: 1753 PRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQAL------------ 1800
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
RGG + I + D+G+Y C +N+ GEA T+TV
Sbjct: 1801 --RGGQR-------LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTV 1838
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/109 (28%), Positives = 44/109 (40%), Gaps = 24/109 (22%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN---I 211
P ++ +V V V L C+ A+P PV++W K + LE PG H++
Sbjct: 789 PSILGEELNVSVVANESVALECQSHAMPPPVLSWWK------DGRPLEPRPGVHLSADKA 842
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+QV A W D G Y C A N G +E H + V
Sbjct: 843 LLQV------DRADVW---------DAGHYTCEALNQAGHSEKHYNLNV 876
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/118 (28%), Positives = 49/118 (41%), Gaps = 24/118 (20%)
Query: 152 EFAPVVVVPPR--------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEE 203
+F V+V PR H + G +V L CE P P + W K +G+ ++
Sbjct: 1925 DFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLK-----DGSPLGQD 1979
Query: 204 LPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
+ G H+ + GG +++ LR D G Y C A N GE TV VL
Sbjct: 1980 M-GPHLRFYLD--GGS--------LVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVL 2026
Score = 37.7 bits (86), Expect = 0.011
Identities = 28/100 (28%), Positives = 37/100 (37%), Gaps = 21/100 (21%)
Query: 155 PVVVVPPRSVHNV-TGAQVGLSCEVRAVPTPVITWRKVTK--SPEGTQALEELPGDHVNI 211
P + +PP V V L+C P+P + W K SP GT L+ PG V
Sbjct: 695 PRITLPPSLPGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-- 752
Query: 212 AVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGE 251
+ + R D G Y C A + VGE
Sbjct: 753 ----------------LTLASARASDSGRYSCVAVSAVGE 776
Score = 36.2 bits (82), Expect = 0.032
Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 36/121 (29%)
Query: 145 KARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEEL 204
+AR G E+ +V P ++ C+ A+P P +TW + E+
Sbjct: 1469 EARGGVTEYREIVENNPAYLY----------CDTNAIPPPDLTWYR-----------EDQ 1507
Query: 205 P---GDHVNIAVQVRGGPSDHEATAWILINPL-RKEDEGVYQCHAANMVGEAESHSTVTV 260
P GD V++ ++GG +L PL R E+ G Y C A+N VGE H + V
Sbjct: 1508 PLSAGDEVSV---LQGGR--------VLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 1556
Query: 261 L 261
L
Sbjct: 1557 L 1557
Score = 35.0 bits (79), Expect = 0.072
Identities = 31/118 (26%), Positives = 40/118 (33%), Gaps = 21/118 (17%)
Query: 154 APVVVVPPRSVHNVTG---AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN 210
AP +V PR V G Q+ L C V A P P ITW +
Sbjct: 2296 APPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR------------------DG 2337
Query: 211 IAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRS 268
I +Q E ++ + L D G Y C A N G V + + RS
Sbjct: 2338 IVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRS 2395
Score = 34.7 bits (78), Expect = 0.094
Identities = 26/106 (24%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P+ V + V + + L CE AVP P I W K + + L+ L +
Sbjct: 1358 PLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL----- 1412
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ I P + D G Y C A N+ GE + V +
Sbjct: 1413 -------------LQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLI 1445
Score = 33.9 bits (76), Expect = 0.16
Identities = 33/129 (25%), Positives = 50/129 (38%), Gaps = 32/129 (24%)
Query: 144 HKARDGPCEFAPVVVVPPRSVHN---------VTGAQVGLSCEVRAVPTPVITWRKVTKS 194
++A + F+ V+VPP S+ N + G L C V P P +TW K +
Sbjct: 1145 NEAGEARRNFSVEVLVPP-SIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRP 1203
Query: 195 PEGTQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKE--DEGVYQCHAANMVGEA 252
+ G + H + +L+ L+ G Y C AAN VGE
Sbjct: 1204 --------------------LARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEK 1243
Query: 253 ESHSTVTVL 261
H ++VL
Sbjct: 1244 TKHFQLSVL 1252
Score = 33.5 bits (75), Expect = 0.21
Identities = 29/106 (27%), Positives = 39/106 (36%), Gaps = 20/106 (18%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
PV P G ++ L C R PTP I W V P
Sbjct: 2847 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWT-VNDRP------------------- 2886
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
V G S+ + + + + +ED G Y C A N VG ++ S V V
Sbjct: 2887 VTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHV 2932
Score = 33.5 bits (75), Expect = 0.21
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 28/144 (19%)
Query: 110 QRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVVVPPRSVHNVTG 169
QR V D +Y VC R T H+ +A E +V P G
Sbjct: 2901 QRAAVSREDSGTY--VCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYLVEP-------VG 2951
Query: 170 AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEATAWIL 229
+ L C VR P P I W K + LP ++ Q++ G +
Sbjct: 2952 GSIQLDCVVRGDPVPDIHWIK-----------DGLPLRGSHLRHQLQNGS--------LT 2992
Query: 230 INPLRKEDEGVYQCHAANMVGEAE 253
I ++D G YQC A N +G A+
Sbjct: 2993 IRRTERDDAGRYQCLAENEMGVAK 3016
Score = 32.7 bits (73), Expect = 0.36
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 26/123 (21%)
Query: 146 ARDGPCEFAPVVVVPPR--------SVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEG 197
A + +++ V VPP+ V + G + L C+ P P I W +
Sbjct: 391 AGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWL------QN 444
Query: 198 TQALEELPGDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHST 257
+ EEL G V +A Q G + H I+ + + G++ C A N G A +
Sbjct: 445 GRPAEELAG--VQVASQ---GTTLH-------IDHVELDHSGLFACQATNEAGTAGAEVE 492
Query: 258 VTV 260
V+V
Sbjct: 493 VSV 495
Score = 32.7 bits (73), Expect = 0.36
Identities = 25/108 (23%), Positives = 43/108 (39%), Gaps = 18/108 (16%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P + P +V+ L C+ VP P+++WRK + +P D + +
Sbjct: 2391 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRK-----------DRVPLDPRSPRFE 2439
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
+ S + I P+ +D G Y C A+N G + VL+
Sbjct: 2440 ILPEGS-------LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLE 2480
Score = 32.0 bits (71), Expect = 0.61
Identities = 31/109 (28%), Positives = 43/109 (39%), Gaps = 27/109 (24%)
Query: 152 EFAPVVVVPP--------RSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEE 203
+F +V+ PP + V + GA V L C VPTP + W K + P
Sbjct: 116 DFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK-DRQP-------V 167
Query: 204 LP-GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGE 251
LP G H+ + E + I DEG YQC A + G+
Sbjct: 168 LPGGPHLQV----------QEDGQVLRITGSHVGDEGRYQCVAFSPAGQ 206
Score = 31.6 bits (70), Expect = 0.80
Identities = 29/108 (26%), Positives = 42/108 (38%), Gaps = 24/108 (22%)
Query: 152 EFAPVVVVPPRSVHN------VTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELP 205
E A V+VPP + A V L C VP P ++W K G Q +
Sbjct: 595 EVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFK------GHQPVSSWM 648
Query: 206 GDHVNIAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAE 253
G V++ +V + I + D G Y+C A+N+ G E
Sbjct: 649 GVTVSVDGRV------------LRIEQAQLSDAGSYRCVASNVAGSTE 684
Score = 30.8 bits (68), Expect = 1.4
Identities = 26/102 (25%), Positives = 35/102 (34%), Gaps = 18/102 (17%)
Query: 160 PPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGP 219
PP V V L C P P +TW + P G + +L G
Sbjct: 982 PPTQVSVVQDGVATLECNATGKPPPTVTWER-DGQPVGAELGLQLQNQ----------GQ 1030
Query: 220 SDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVL 261
S H + + G Y C A N+ G AE ++VL
Sbjct: 1031 SLH-------VERAQAAHTGRYSCVAENLAGRAERKFELSVL 1065
Score = 30.4 bits (67), Expect = 1.8
Identities = 28/118 (23%), Positives = 46/118 (38%), Gaps = 31/118 (26%)
Query: 165 HNVTGAQVGL-SCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPSDHE 223
HN G L + V PT + + +G+ L PG+ V + VRG P H
Sbjct: 2011 HNPAGEDARLHTVNVLVPPT-------IKQGADGSGTLVSRPGELVTMVCPVRGSPPIH- 2062
Query: 224 ATAW---------------------ILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+W + I+ ++ D G++ C AA+ G A+ + T+ V
Sbjct: 2063 -VSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVADRNFTLQV 2119
Score = 30.0 bits (66), Expect = 2.3
Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 25/100 (25%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQVRGGPS 220
P + GA + L C+ + P P ITW K QAL L +
Sbjct: 2220 PTELSLTPGAPMELLCDAQGTPQPNITWHK------DGQALTRL--------------EN 2259
Query: 221 DHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ AT LR D G+Y C A + G E V V
Sbjct: 2260 NSRAT-----RVLRVRDAGLYTCLAESPAGAIEKSFRVRV 2294
Score = 29.3 bits (64), Expect = 4.0
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 5/41 (12%)
Query: 226 AWILINPLRKE-----DEGVYQCHAANMVGEAESHSTVTVL 261
A+ L PL+ E DEG+Y C A N+ GE++ + VL
Sbjct: 561 AYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVL 601
Score = 28.5 bits (62), Expect = 6.8
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 20/101 (19%)
Query: 161 PRSVHNVTGAQVGLSCEVRAVPTPVITW-RKVTKSPEGTQALEELPGDHVNIAVQVRGGP 219
P V V G V L C R P+P ++W + E ++ E G + +
Sbjct: 321 PYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRL-------E 373
Query: 220 SDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
S EA++ G+Y C A++ GEA +V V
Sbjct: 374 SPGEASS------------GLYSCVASSPAGEAVLQYSVEV 402
Score = 28.1 bits (61), Expect = 8.8
Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 16/106 (15%)
Query: 155 PVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAVQ 214
P + P ++ L CE P P++ W K G ++ +Q
Sbjct: 2482 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWK--------------DGQKLDFRLQ 2527
Query: 215 VRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+G + A +L P +D ++C +N VGEA VTV
Sbjct: 2528 -QGAYRLLPSNALLLTAP-GPQDSAQFECVVSNEVGEAHRLYQVTV 2571
Score = 28.1 bits (61), Expect = 8.8
Identities = 28/110 (25%), Positives = 37/110 (33%), Gaps = 24/110 (21%)
Query: 157 VVVPPRSVHNVTG------AQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVN 210
V VPP + T A V L+C +P P ++W K G Q
Sbjct: 2571 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKA-----GAQ----------- 2614
Query: 211 IAVQVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ RG + + I G Y C A N G A H +TV
Sbjct: 2615 --LGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTV 2662
>gi|13994372 keratin associated protein 17-1 [Homo sapiens]
Length = 105
Score = 46.2 bits (108), Expect = 3e-05
Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 6/80 (7%)
Query: 41 CRPEGCPAPAPCPAPGISALDECGCCARCLGAE--GASCGGRAG-GRCGPGLVCASQAAG 97
C+P C C G S GC C G+ G+ CGG G G CG G C S G
Sbjct: 24 CQPGCCGCCGSCCGCGGSGCGGSGCGGSCCGSSCCGSGCGGCGGCGGCGGG-CCGSSCCG 82
Query: 98 AAPEGTGLC--VCAQRGTVC 115
++ G+G C VC Q +C
Sbjct: 83 SSCCGSGCCGPVCCQPTPIC 102
Score = 43.5 bits (101), Expect = 2e-04
Identities = 27/79 (34%), Positives = 30/79 (37%), Gaps = 9/79 (11%)
Query: 52 CPAPGISALDECGCCARCLGAEGASCGGR-AGGRCGPGLVCAS---QAAGAAPEGTGLCV 107
C PG CGCC C G G+ CGG GG C C S G G G C
Sbjct: 23 CCQPGC-----CGCCGSCCGCGGSGCGGSGCGGSCCGSSCCGSGCGGCGGCGGCGGGCCG 77
Query: 108 CAQRGTVCGSDGRSYPSVC 126
+ G+ C G P C
Sbjct: 78 SSCCGSSCCGSGCCGPVCC 96
Score = 35.8 bits (81), Expect = 0.042
Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 9/78 (11%)
Query: 46 CPAPA-PCPAPGISALDECGCCARCLGAEGASCG----GRAGGRCGPGLVCASQAAGAAP 100
CP C + +EC C C G G+ CG G G CG G C S G+
Sbjct: 4 CPGDCFTCCTQEQNCCEECCCQPGCCGCCGSCCGCGGSGCGGSGCG-GSCCGSSCCGSGC 62
Query: 101 EGTGLC-VCAQRGTVCGS 117
G G C C G CGS
Sbjct: 63 GGCGGCGGCG--GGCCGS 78
>gi|208022668 endothelial cell-specific molecule 1 isoform b
precursor [Homo sapiens]
Length = 134
Score = 45.8 bits (107), Expect = 4e-05
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 8/80 (10%)
Query: 41 CRPEGCPAPAPCPAPGISALDECGCCARCLGAEGASC----GGRAGGRCGPGLVCASQAA 96
C C + C + LD+CGCC C G +C G G +CGPGL C +
Sbjct: 32 CDSSECKSSPRCKR---TVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRC-QPSN 87
Query: 97 GAAPEGTGLCVCAQRGTVCG 116
G P G +C + G
Sbjct: 88 GEDPFGEEFGICKEHDMASG 107
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 45.8 bits (107), Expect = 4e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 19/109 (17%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
AP V + S H G +V +SC PTP I+W + +QAL+E HV
Sbjct: 490 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSR------ESQALQEDSRIHV---- 539
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
+A ++I + ED G Y C A N VG + T+ D
Sbjct: 540 ---------DAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD 579
Score = 45.4 bits (106), Expect = 5e-05
Identities = 60/237 (25%), Positives = 81/237 (34%), Gaps = 56/237 (23%)
Query: 44 EGCPAPAPC-----PAPGISALDECGCCARCLGAEGASCGGRAGGRCGPGLVCASQAAGA 98
EG PA PC PAP I+ E L + G G L+ A +A
Sbjct: 872 EGVPASLPCVASGVPAPTITWTKE----TNALTSRGPHYNVSKEGT----LLIAQPSA-- 921
Query: 99 APEGTGLCVCAQRGTVCGSDGRSYPSVCALRLRARHTPRAHPGHLHKARDGPCEFAPVVV 158
+ G VC TV S +RL PR H A
Sbjct: 922 --QDAGAYVCTATNTVGFSSQE-------MRLSVNTKPRIHMNGSRNAN----------- 961
Query: 159 VPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKS-PEGTQALEELPGDHVNIAVQVRG 217
P V G +V L CE + P P++TW K ++ P T LP + +A QV+
Sbjct: 962 -VPLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLA-QVQV 1019
Query: 218 GPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLDLSKYRSFHFPAP 274
G S H Y+C A+N G A + V + ++ P P
Sbjct: 1020 GDSGH------------------YECTASNPAGSASHRYVLGVQGRTSWQPQSLPVP 1058
Score = 39.3 bits (90), Expect = 0.004
Identities = 26/107 (24%), Positives = 41/107 (38%), Gaps = 12/107 (11%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
AP + PR V G L+C P P +TWR+ P G +
Sbjct: 668 APQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLR------------LG 715
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
RG S + + + ED+ Y C A N+ G+ ++ + + V
Sbjct: 716 AGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 762
Score = 29.3 bits (64), Expect = 4.0
Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 29/96 (30%)
Query: 169 GAQVGLSCEVRAVPTPVITWRK----VTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEA 224
G + L CE VP P + W + + +PEG+ +
Sbjct: 595 GEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGS-------------------------S 629
Query: 225 TAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + I ++ D G Y C A N +G+A + + V
Sbjct: 630 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 665
>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
sapiens]
Length = 790
Score = 45.8 bits (107), Expect = 4e-05
Identities = 33/109 (30%), Positives = 46/109 (42%), Gaps = 19/109 (17%)
Query: 154 APVVVVPPRSVHNVTGAQVGLSCEVRAVPTPVITWRKVTKSPEGTQALEELPGDHVNIAV 213
AP V + S H G +V +SC PTP I+W + +QAL+E HV
Sbjct: 606 APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSR------ESQALQEDSRIHV---- 655
Query: 214 QVRGGPSDHEATAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTVLD 262
+A ++I + ED G Y C A N VG + T+ D
Sbjct: 656 ---------DAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD 695
Score = 29.3 bits (64), Expect = 4.0
Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 29/96 (30%)
Query: 169 GAQVGLSCEVRAVPTPVITWRK----VTKSPEGTQALEELPGDHVNIAVQVRGGPSDHEA 224
G + L CE VP P + W + + +PEG+ +
Sbjct: 711 GEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGS-------------------------S 745
Query: 225 TAWILINPLRKEDEGVYQCHAANMVGEAESHSTVTV 260
+ + I ++ D G Y C A N +G+A + + V
Sbjct: 746 SGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 781
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,567,769
Number of Sequences: 37866
Number of extensions: 900127
Number of successful extensions: 7227
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 220
Number of HSP's successfully gapped in prelim test: 362
Number of HSP's that attempted gapping in prelim test: 4912
Number of HSP's gapped (non-prelim): 2006
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.