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Search of human proteins with 13430848
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13430848 nuclear receptor subfamily 1, group D, member 1
[Homo sapiens]
(614 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom... 1249 0.0
gi|224177491 nuclear receptor subfamily 1, group D, member 2 iso... 519 e-147
gi|224177493 nuclear receptor subfamily 1, group D, member 2 iso... 496 e-140
gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens] 220 3e-57
gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens] 220 3e-57
gi|50348666 peroxisome proliferative activated receptor, alpha [... 137 4e-32
gi|7549811 peroxisome proliferative activated receptor, alpha [H... 137 4e-32
gi|116284373 peroxisome proliferative activated receptor gamma i... 135 1e-31
gi|20336229 peroxisome proliferative activated receptor gamma is... 135 1e-31
gi|116284368 peroxisome proliferative activated receptor gamma i... 135 1e-31
gi|116284370 peroxisome proliferative activated receptor gamma i... 135 1e-31
gi|29171750 peroxisome proliferative activated receptor, delta i... 133 4e-31
gi|5453940 peroxisome proliferative activated receptor, delta is... 133 4e-31
gi|19743907 RAR-related orphan receptor B [Homo sapiens] 133 5e-31
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens] 131 2e-30
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens] 129 1e-29
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens] 128 2e-29
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens] 128 2e-29
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso... 126 7e-29
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso... 126 7e-29
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 123 6e-28
gi|7706625 retinoic acid receptor, beta isoform 2 [Homo sapiens] 123 6e-28
gi|223718070 retinoic acid receptor, alpha isoform 4 [Homo sapiens] 121 2e-27
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 121 2e-27
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 121 2e-27
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 121 2e-27
gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Hom... 120 3e-27
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 120 4e-27
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 120 4e-27
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 114 3e-25
>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
sapiens]
Length = 614
Score = 1249 bits (3233), Expect = 0.0
Identities = 614/614 (100%), Positives = 614/614 (100%)
Query: 1 MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL 60
MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL
Sbjct: 1 MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL 60
Query: 61 TQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTS 120
TQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTS
Sbjct: 61 TQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTS 120
Query: 121 NITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRI 180
NITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRI
Sbjct: 121 NITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRI 180
Query: 181 NRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETS 240
NRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETS
Sbjct: 181 NRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETS 240
Query: 241 PTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIF 300
PTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIF
Sbjct: 241 PTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIF 300
Query: 301 TYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQ 360
TYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQ
Sbjct: 301 TYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQ 360
Query: 361 APSSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPM 420
APSSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPM
Sbjct: 361 APSSYPPTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEGKAPANSPRQGNSKNVLLACPM 420
Query: 421 NMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVL 480
NMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVL
Sbjct: 421 NMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVL 480
Query: 481 MVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLF 540
MVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLF
Sbjct: 481 MVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLF 540
Query: 541 TAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNN 600
TAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNN
Sbjct: 541 TAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNN 600
Query: 601 MHSEKLLSFRVDAQ 614
MHSEKLLSFRVDAQ
Sbjct: 601 MHSEKLLSFRVDAQ 614
>gi|224177491 nuclear receptor subfamily 1, group D, member 2
isoform 1 [Homo sapiens]
Length = 579
Score = 519 bits (1337), Expect = e-147
Identities = 313/615 (50%), Positives = 382/615 (62%), Gaps = 53/615 (8%)
Query: 9 NTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSLTQDPAR-S 67
N GGVI YI SS S+ +SP S +S+ S SFQS + P+ P S +P
Sbjct: 4 NAGGVIAYISSSSSA---SSPASCHSEGSENSFQSSSSSVPS-SPNSSNSDTNGNPKNGD 59
Query: 68 FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTSNITKLNG 127
+I L +D S +S SS+ PG +KS S +TK +G
Sbjct: 60 LANIEGILKNDRIDCSMKTSKSSA--------PGM-------------TKSHSGVTKFSG 98
Query: 128 MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQ 187
MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYK+CLKNENCSI+R+NRNRCQQ
Sbjct: 99 MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQ 158
Query: 188 CRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAM-NLANNQLSSQCPLETSPTQH-P 245
CRFKKCLSVGMSRDAVRFGRIPKREKQRML EMQSAM + N+Q S +T H
Sbjct: 159 CRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQ 218
Query: 246 TPGPMGPSPPPAPVPSPLVGFSQFPQQ-LTPPRSPSPEPTVEDVISQVARAHREIFTYAH 304
T P P P Q Q+ + PS + E+VI V RAH++ F Y
Sbjct: 219 TALPAQEQLRPKP---------QLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQ 269
Query: 305 DKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQAPSS 364
++ +S + P + + C + + + LNG Q
Sbjct: 270 EQQENSAESMQPQRGERIPKNMEQYNLNHDHCGNGLSSH--FPCSESQQHLNG--QFKGR 325
Query: 365 YPPTWPPGPA-----HHSCHQSNSNGHRLC---PTHVYAAPEGKAPANSPRQGNSKNVLL 416
+P G A H + SN+ R+C P ++ E K NS + L
Sbjct: 326 NIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPIDGFSQNENK---NSYLCNTGGRMHL 382
Query: 417 ACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGT 476
CPM+ P+ ++ EIWE+FSMSFTPAV+EVVEFAK IPGFRDLSQHDQV LLKAGT
Sbjct: 383 VCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGT 442
Query: 477 FEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEE 536
FEVLMVRFASLF+ K++TV FLS YS+ +L +MG GDLL++MF+FSEKLN+L L++EE
Sbjct: 443 FEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEE 502
Query: 537 LGLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLR 596
+ LFTAVVLVSADRSG+EN SVE LQETL+RALR L++KN P E S FTKLLLKLPDLR
Sbjct: 503 MSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLR 562
Query: 597 TLNNMHSEKLLSFRV 611
+LNNMHSE+LL+F+V
Sbjct: 563 SLNNMHSEELLAFKV 577
>gi|224177493 nuclear receptor subfamily 1, group D, member 2
isoform 2 [Homo sapiens]
Length = 504
Score = 496 bits (1276), Expect = e-140
Identities = 286/514 (55%), Positives = 345/514 (67%), Gaps = 29/514 (5%)
Query: 110 SSRVSPSKSTSNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRC 169
SS +KS S +TK +GMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYK+C
Sbjct: 6 SSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKC 65
Query: 170 LKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-LAN 228
LKNENCSI+R+NRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRML EMQSAM + N
Sbjct: 66 LKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMN 125
Query: 229 NQLSSQCPLETSPTQHP-TPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSP-SPEPTVE 286
+Q S +T H T P P P Q Q+ SP S + E
Sbjct: 126 SQFSGHLQNDTLVEHHEQTALPAQEQLRPKP---------QLEQENIKSSSPPSSDFAKE 176
Query: 287 DVISQVARAHREIFTYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTL 346
+VI V RAH++ F Y ++ +S + P + + C + +
Sbjct: 177 EVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDHCGNGLSSHFPC 236
Query: 347 A-AQRHNEALNGLRQAPSSYPPTWPPGPA-----HHSCHQSNSNGHRLC---PTHVYAAP 397
+ +Q+H LNG Q +P G A H + SN+ R+C P ++
Sbjct: 237 SESQQH---LNG--QFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPIDGFSQN 291
Query: 398 EGKAPANSPRQGNSKNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHI 457
E K NS + L CPM+ P+ ++ EIWE+FSMSFTPAV+EVVEFAK I
Sbjct: 292 ENK---NSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRI 348
Query: 458 PGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLL 517
PGFRDLSQHDQV LLKAGTFEVLMVRFASLF+ K++TV FLS YS+ +L +MG GDLL
Sbjct: 349 PGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLL 408
Query: 518 SAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKN 577
++MF+FSEKLN+L L++EE+ LFTAVVLVSADRSG+EN SVE LQETL+RALR L++KN
Sbjct: 409 NSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKN 468
Query: 578 RPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRV 611
P E S FTKLLLKLPDLR+LNNMHSE+LL+F+V
Sbjct: 469 HPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKV 502
>gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]
Length = 497
Score = 220 bits (561), Expect = 3e-57
Identities = 163/499 (32%), Positives = 245/499 (49%), Gaps = 56/499 (11%)
Query: 129 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQC 188
V+ CK+CGD +SG HYGV CEGCKGFFRRS + N Y C + +NC I R +RNRCQ C
Sbjct: 7 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYS-CTRQQNCPIDRTSRNRCQHC 65
Query: 189 RFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPTPG 248
R +KCL++GMSRDAV+FGR+ K+++ + AE+Q L Q Q P+ +P
Sbjct: 66 RLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQK--QLQQRQQQQQEPVVKTP------- 116
Query: 249 PMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHD--K 306
P A L P P S P + +A +Y+++ K
Sbjct: 117 -----PAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAK 171
Query: 307 LGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQAPSSYP 366
G + + + ++ A + + G P+ + + L L Q P SY
Sbjct: 172 AGLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSY- 230
Query: 367 PTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEG-----KAPANSPRQGNSKNV--LLACP 419
S R P YA+ ++ S R+ + LL
Sbjct: 231 ---------------GSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQR 275
Query: 420 MNMYPH----GRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAG 475
N++ G +++ E+WE + T A++ VVEFAK + GF +L Q+DQ+ LLKAG
Sbjct: 276 SNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAG 335
Query: 476 TFEVLMVRFASLFNVKDQTVMFLSRTTYSLQEL-GAMGMGDLLSAMFDFSEKLNSLALTE 534
EV++VR +N ++TV F + Y EL A+G +L+S++FDFS L++L +E
Sbjct: 336 AMEVVLVRMCRAYNADNRTVFFEGK--YGGMELFRALGCSELISSIFDFSHSLSALHFSE 393
Query: 535 EELGLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLP- 593
+E+ L+TA+VL++A R G++ VEQLQ L L + +T R +L KLP
Sbjct: 394 DEIALYTALVLINAHRPGLQEKRKVEQLQYNL-----ELAFHHHLCKTHR-QSILAKLPP 447
Query: 594 --DLRTLNNMHSEKLLSFR 610
LR+L + H E+L F+
Sbjct: 448 KGKLRSLCSQHVERLQIFQ 466
>gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]
Length = 518
Score = 220 bits (561), Expect = 3e-57
Identities = 163/499 (32%), Positives = 245/499 (49%), Gaps = 56/499 (11%)
Query: 129 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQC 188
V+ CK+CGD +SG HYGV CEGCKGFFRRS + N Y C + +NC I R +RNRCQ C
Sbjct: 28 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYS-CTRQQNCPIDRTSRNRCQHC 86
Query: 189 RFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPTPG 248
R +KCL++GMSRDAV+FGR+ K+++ + AE+Q L Q Q P+ +P
Sbjct: 87 RLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQK--QLQQRQQQQQEPVVKTP------- 137
Query: 249 PMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHD--K 306
P A L P P S P + +A +Y+++ K
Sbjct: 138 -----PAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAK 192
Query: 307 LGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLAAQRHNEALNGLRQAPSSYP 366
G + + + ++ A + + G P+ + + L L Q P SY
Sbjct: 193 AGLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSY- 251
Query: 367 PTWPPGPAHHSCHQSNSNGHRLCPTHVYAAPEG-----KAPANSPRQGNSKNV--LLACP 419
S R P YA+ ++ S R+ + LL
Sbjct: 252 ---------------GSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQR 296
Query: 420 MNMYPH----GRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAG 475
N++ G +++ E+WE + T A++ VVEFAK + GF +L Q+DQ+ LLKAG
Sbjct: 297 SNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAG 356
Query: 476 TFEVLMVRFASLFNVKDQTVMFLSRTTYSLQEL-GAMGMGDLLSAMFDFSEKLNSLALTE 534
EV++VR +N ++TV F + Y EL A+G +L+S++FDFS L++L +E
Sbjct: 357 AMEVVLVRMCRAYNADNRTVFFEGK--YGGMELFRALGCSELISSIFDFSHSLSALHFSE 414
Query: 535 EELGLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLP- 593
+E+ L+TA+VL++A R G++ VEQLQ L L + +T R +L KLP
Sbjct: 415 DEIALYTALVLINAHRPGLQEKRKVEQLQYNL-----ELAFHHHLCKTHR-QSILAKLPP 468
Query: 594 --DLRTLNNMHSEKLLSFR 610
LR+L + H E+L F+
Sbjct: 469 KGKLRSLCSQHVERLQIFQ 487
>gi|50348666 peroxisome proliferative activated receptor, alpha
[Homo sapiens]
Length = 468
Score = 137 bits (344), Expect = 4e-32
Identities = 72/155 (46%), Positives = 98/155 (63%), Gaps = 21/155 (13%)
Query: 83 SSSSSSSSSSSF------YNGSPPGSLQVAMEDSSRVSPSKSTSNIT-----------KL 125
S S SS SF Y GS PGS + D+ +SP+ S S++T
Sbjct: 38 SQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDT--LSPASSPSSVTYPVVPGSVDESPS 95
Query: 126 NGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRC 185
+ + C++CGD ASG+HYGVHACEGCKGFFRR+I+ + Y +C + +C I + NRN+C
Sbjct: 96 GALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKC--DRSCKIQKKNRNKC 153
Query: 186 QQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEM 220
Q CRF KCLSVGMS +A+RFGR+P+ EK ++ AE+
Sbjct: 154 QYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEI 188
Score = 100 bits (248), Expect = 5e-21
Identities = 57/160 (35%), Positives = 90/160 (56%), Gaps = 3/160 (1%)
Query: 447 VREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQ 506
V E+ EFAK IPGF +L +DQVTLLK G +E + +S+ N KD ++ + +
Sbjct: 284 VTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMN-KDGMLVAYGNGFITRE 342
Query: 507 ELGAMGMG--DLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQE 564
L ++ D++ FDF+ K N+L L + ++ LF A ++ DR G+ N +E++QE
Sbjct: 343 FLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQE 402
Query: 565 TLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSE 604
++ LR + N P + F KLL K+ DLR L H++
Sbjct: 403 GIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQ 442
>gi|7549811 peroxisome proliferative activated receptor, alpha [Homo
sapiens]
Length = 468
Score = 137 bits (344), Expect = 4e-32
Identities = 72/155 (46%), Positives = 98/155 (63%), Gaps = 21/155 (13%)
Query: 83 SSSSSSSSSSSF------YNGSPPGSLQVAMEDSSRVSPSKSTSNIT-----------KL 125
S S SS SF Y GS PGS + D+ +SP+ S S++T
Sbjct: 38 SQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDT--LSPASSPSSVTYPVVPGSVDESPS 95
Query: 126 NGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRC 185
+ + C++CGD ASG+HYGVHACEGCKGFFRR+I+ + Y +C + +C I + NRN+C
Sbjct: 96 GALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKC--DRSCKIQKKNRNKC 153
Query: 186 QQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEM 220
Q CRF KCLSVGMS +A+RFGR+P+ EK ++ AE+
Sbjct: 154 QYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEI 188
Score = 100 bits (248), Expect = 5e-21
Identities = 57/160 (35%), Positives = 90/160 (56%), Gaps = 3/160 (1%)
Query: 447 VREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQ 506
V E+ EFAK IPGF +L +DQVTLLK G +E + +S+ N KD ++ + +
Sbjct: 284 VTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMN-KDGMLVAYGNGFITRE 342
Query: 507 ELGAMGMG--DLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQE 564
L ++ D++ FDF+ K N+L L + ++ LF A ++ DR G+ N +E++QE
Sbjct: 343 FLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQE 402
Query: 565 TLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSE 604
++ LR + N P + F KLL K+ DLR L H++
Sbjct: 403 GIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQ 442
>gi|116284373 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 135 bits (340), Expect = 1e-31
Identities = 60/101 (59%), Positives = 81/101 (80%), Gaps = 2/101 (1%)
Query: 128 MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQ 187
M + C+VCGD ASGFHYGVHACEGCKGFFRR+I+ + Y RC + NC I + +RN+CQ
Sbjct: 107 MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQY 164
Query: 188 CRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLAN 228
CRF+KCL+VGMS +A+RFGR+P+ EK+++LAE+ S ++ N
Sbjct: 165 CRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLN 205
Score = 108 bits (271), Expect = 1e-23
Identities = 62/163 (38%), Positives = 96/163 (58%), Gaps = 3/163 (1%)
Query: 446 AVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSL 505
AV+E+ E+AK IPGF +L +DQVTLLK G E++ ASL N KD ++ + +
Sbjct: 292 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMN-KDGVLISEGQGFMTR 350
Query: 506 QELGAMG--MGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQ 563
+ L ++ GD + F+F+ K N+L L + +L +F AV+++S DR G+ N +E +Q
Sbjct: 351 EFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQ 410
Query: 564 ETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKL 606
+ LL+AL + N P + F KLL K+ DLR + H + L
Sbjct: 411 DNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLL 453
>gi|20336229 peroxisome proliferative activated receptor gamma
isoform 2 [Homo sapiens]
Length = 505
Score = 135 bits (340), Expect = 1e-31
Identities = 60/101 (59%), Positives = 81/101 (80%), Gaps = 2/101 (1%)
Query: 128 MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQ 187
M + C+VCGD ASGFHYGVHACEGCKGFFRR+I+ + Y RC + NC I + +RN+CQ
Sbjct: 135 MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQY 192
Query: 188 CRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLAN 228
CRF+KCL+VGMS +A+RFGR+P+ EK+++LAE+ S ++ N
Sbjct: 193 CRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLN 233
Score = 108 bits (271), Expect = 1e-23
Identities = 62/163 (38%), Positives = 96/163 (58%), Gaps = 3/163 (1%)
Query: 446 AVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSL 505
AV+E+ E+AK IPGF +L +DQVTLLK G E++ ASL N KD ++ + +
Sbjct: 320 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMN-KDGVLISEGQGFMTR 378
Query: 506 QELGAMG--MGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQ 563
+ L ++ GD + F+F+ K N+L L + +L +F AV+++S DR G+ N +E +Q
Sbjct: 379 EFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQ 438
Query: 564 ETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKL 606
+ LL+AL + N P + F KLL K+ DLR + H + L
Sbjct: 439 DNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLL 481
>gi|116284368 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 135 bits (340), Expect = 1e-31
Identities = 60/101 (59%), Positives = 81/101 (80%), Gaps = 2/101 (1%)
Query: 128 MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQ 187
M + C+VCGD ASGFHYGVHACEGCKGFFRR+I+ + Y RC + NC I + +RN+CQ
Sbjct: 107 MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQY 164
Query: 188 CRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLAN 228
CRF+KCL+VGMS +A+RFGR+P+ EK+++LAE+ S ++ N
Sbjct: 165 CRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLN 205
Score = 108 bits (271), Expect = 1e-23
Identities = 62/163 (38%), Positives = 96/163 (58%), Gaps = 3/163 (1%)
Query: 446 AVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSL 505
AV+E+ E+AK IPGF +L +DQVTLLK G E++ ASL N KD ++ + +
Sbjct: 292 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMN-KDGVLISEGQGFMTR 350
Query: 506 QELGAMG--MGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQ 563
+ L ++ GD + F+F+ K N+L L + +L +F AV+++S DR G+ N +E +Q
Sbjct: 351 EFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQ 410
Query: 564 ETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKL 606
+ LL+AL + N P + F KLL K+ DLR + H + L
Sbjct: 411 DNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLL 453
>gi|116284370 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 135 bits (340), Expect = 1e-31
Identities = 60/101 (59%), Positives = 81/101 (80%), Gaps = 2/101 (1%)
Query: 128 MVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQ 187
M + C+VCGD ASGFHYGVHACEGCKGFFRR+I+ + Y RC + NC I + +RN+CQ
Sbjct: 107 MAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQY 164
Query: 188 CRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLAN 228
CRF+KCL+VGMS +A+RFGR+P+ EK+++LAE+ S ++ N
Sbjct: 165 CRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLN 205
Score = 108 bits (271), Expect = 1e-23
Identities = 62/163 (38%), Positives = 96/163 (58%), Gaps = 3/163 (1%)
Query: 446 AVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSL 505
AV+E+ E+AK IPGF +L +DQVTLLK G E++ ASL N KD ++ + +
Sbjct: 292 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMN-KDGVLISEGQGFMTR 350
Query: 506 QELGAMG--MGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQ 563
+ L ++ GD + F+F+ K N+L L + +L +F AV+++S DR G+ N +E +Q
Sbjct: 351 EFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQ 410
Query: 564 ETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKL 606
+ LL+AL + N P + F KLL K+ DLR + H + L
Sbjct: 411 DNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLL 453
>gi|29171750 peroxisome proliferative activated receptor, delta
isoform 2 [Homo sapiens]
Length = 361
Score = 133 bits (335), Expect = 4e-31
Identities = 64/144 (44%), Positives = 94/144 (65%), Gaps = 18/144 (12%)
Query: 78 DGSPSSSSSSSSSSSSFYNGSPPG---SLQVAMEDSSRVSPSKSTSNITKLNGMVLLCKV 134
+G P + SSS + + SPP LQ+ + +S + + C+V
Sbjct: 30 NGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGAS-------------CGSLNMECRV 76
Query: 135 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCL 194
CGD ASGFHYGVHACEGCKGFFRR+I+ ++Y++C +C I + NRN+CQ CRF+KCL
Sbjct: 77 CGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKC--ERSCKIQKKNRNKCQYCRFQKCL 134
Query: 195 SVGMSRDAVRFGRIPKREKQRMLA 218
++GMS +A+RFGR+P+ EK++++A
Sbjct: 135 ALGMSHNAIRFGRMPEAEKRKLVA 158
Score = 62.0 bits (149), Expect = 2e-09
Identities = 37/102 (36%), Positives = 57/102 (55%), Gaps = 3/102 (2%)
Query: 447 VREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQ 506
VRE+ EFAK IP F L +DQVTLLK G E + AS+ N KD ++ + +
Sbjct: 257 VRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVN-KDGLLVANGSGFVTRE 315
Query: 507 ELGAM--GMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLV 546
L ++ D++ F+F+ K N+L L + +L LF A +++
Sbjct: 316 FLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIIL 357
>gi|5453940 peroxisome proliferative activated receptor, delta
isoform 1 [Homo sapiens]
Length = 441
Score = 133 bits (335), Expect = 4e-31
Identities = 64/144 (44%), Positives = 94/144 (65%), Gaps = 18/144 (12%)
Query: 78 DGSPSSSSSSSSSSSSFYNGSPPG---SLQVAMEDSSRVSPSKSTSNITKLNGMVLLCKV 134
+G P + SSS + + SPP LQ+ + +S + + C+V
Sbjct: 30 NGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGAS-------------CGSLNMECRV 76
Query: 135 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCL 194
CGD ASGFHYGVHACEGCKGFFRR+I+ ++Y++C +C I + NRN+CQ CRF+KCL
Sbjct: 77 CGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKC--ERSCKIQKKNRNKCQYCRFQKCL 134
Query: 195 SVGMSRDAVRFGRIPKREKQRMLA 218
++GMS +A+RFGR+P+ EK++++A
Sbjct: 135 ALGMSHNAIRFGRMPEAEKRKLVA 158
Score = 100 bits (250), Expect = 3e-21
Identities = 61/162 (37%), Positives = 90/162 (55%), Gaps = 3/162 (1%)
Query: 447 VREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQ 506
VRE+ EFAK IP F L +DQVTLLK G E + AS+ N KD ++ + +
Sbjct: 257 VRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVN-KDGLLVANGSGFVTRE 315
Query: 507 ELGAMG--MGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQE 564
L ++ D++ F+F+ K N+L L + +L LF A +++ DR G+ N VE +Q+
Sbjct: 316 FLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQD 375
Query: 565 TLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKL 606
T+LRAL + N P F KLL K+ DLR L H++ +
Sbjct: 376 TILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMM 417
>gi|19743907 RAR-related orphan receptor B [Homo sapiens]
Length = 459
Score = 133 bits (334), Expect = 5e-31
Identities = 71/178 (39%), Positives = 112/178 (62%), Gaps = 2/178 (1%)
Query: 433 QEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKD 492
+ +W+ ++ T A++ VVEFAK I GF +L Q+DQ+ LLK+G EV++VR FN +
Sbjct: 256 EALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLKSGCLEVVLVRMCRAFNPLN 315
Query: 493 QTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSG 552
TV+F + +Q A+G DL++ FDF++ L SL LTEEE+ LF++ VL+S DR+
Sbjct: 316 NTVLFEGKYG-GMQMFKALGSDDLVNEAFDFAKNLCSLQLTEEEIALFSSAVLISPDRAW 374
Query: 553 MENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610
+ V++LQE + AL+ ++ KN L+ KL+ K+P + + N+H EKL F+
Sbjct: 375 LIEPRKVQKLQEKIYFALQHVIQKNH-LDDETLAKLIAKIPTITAVCNLHGEKLQVFK 431
Score = 127 bits (319), Expect = 3e-29
Identities = 58/106 (54%), Positives = 72/106 (67%), Gaps = 1/106 (0%)
Query: 129 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQC 188
V+ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + NC I R NRNRCQ C
Sbjct: 7 VIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYS-CPRQRNCLIDRTNRNRCQHC 65
Query: 189 RFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQ 234
R +KCL++GMSRDAV+FGR+ K+++ + AE+Q Q Q
Sbjct: 66 RLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQQRLQEQRQQQ 111
>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
Length = 523
Score = 131 bits (329), Expect = 2e-30
Identities = 72/175 (41%), Positives = 100/175 (57%), Gaps = 9/175 (5%)
Query: 73 PSLSDDGSPSSSSSSSS-----SSSSFYNGSPPGSLQVAMEDSSRVSPSKSTSNITKLNG 127
P+ S+ GS + +++ S + S PP V + S S S + T +
Sbjct: 10 PAASEPGSSGADAAAGSRETPLNQESARKSEPPAP--VRRQSYSSTSRGISVTKKTHTSQ 67
Query: 128 MVLL-CKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQ 186
+ ++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I R +RNRCQ
Sbjct: 68 IEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQ 126
Query: 187 QCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSP 241
CR +KCL+VGMSRDAV+FGR+ K+++ + AE+Q + Q P E P
Sbjct: 127 HCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP 181
Score = 128 bits (321), Expect = 2e-29
Identities = 70/176 (39%), Positives = 112/176 (63%), Gaps = 2/176 (1%)
Query: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
+W+ ++ T A++ VVEFAK I GF +L Q+DQ+ LLKAG+ EV+ +R F+ ++ T
Sbjct: 319 MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNT 378
Query: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
V F + S ++G D +S +F+F + L S+ LTE+E+ LF+A VL+SADRS ++
Sbjct: 379 VYFDGKYA-SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ 437
Query: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610
+E+LQ+ + AL+ ++ KN E TKL+ K+ LR L H+EKL++F+
Sbjct: 438 EKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFK 492
>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
Length = 548
Score = 129 bits (323), Expect = 1e-29
Identities = 73/179 (40%), Positives = 103/179 (57%), Gaps = 13/179 (7%)
Query: 70 SIPPSLSDDGSPSSSSSSSSSSSSF-------YNGSPPGSLQVAMEDSSRVSPSKSTSNI 122
S P+ + +G+ SSS+ SS S + ++G+ + E S + P+ + I
Sbjct: 34 SATPTPAGEGARSSSTCSSLSRLFWSQLEHINWDGATAKNFINLREFFSFLLPALRKAQI 93
Query: 123 TKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINR 182
++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I R +R
Sbjct: 94 E-----IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSR 147
Query: 183 NRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSP 241
NRCQ CR +KCL+VGMSRDAV+FGR+ K+++ + AE+Q + Q P E P
Sbjct: 148 NRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP 206
Score = 128 bits (321), Expect = 2e-29
Identities = 70/176 (39%), Positives = 112/176 (63%), Gaps = 2/176 (1%)
Query: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
+W+ ++ T A++ VVEFAK I GF +L Q+DQ+ LLKAG+ EV+ +R F+ ++ T
Sbjct: 344 MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNT 403
Query: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
V F + S ++G D +S +F+F + L S+ LTE+E+ LF+A VL+SADRS ++
Sbjct: 404 VYFDGKYA-SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ 462
Query: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610
+E+LQ+ + AL+ ++ KN E TKL+ K+ LR L H+EKL++F+
Sbjct: 463 EKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFK 517
>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
Length = 468
Score = 128 bits (321), Expect = 2e-29
Identities = 70/176 (39%), Positives = 112/176 (63%), Gaps = 2/176 (1%)
Query: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
+W+ ++ T A++ VVEFAK I GF +L Q+DQ+ LLKAG+ EV+ +R F+ ++ T
Sbjct: 264 MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNT 323
Query: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
V F + S ++G D +S +F+F + L S+ LTE+E+ LF+A VL+SADRS ++
Sbjct: 324 VYFDGKYA-SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ 382
Query: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610
+E+LQ+ + AL+ ++ KN E TKL+ K+ LR L H+EKL++F+
Sbjct: 383 EKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFK 437
Score = 127 bits (318), Expect = 4e-29
Identities = 59/113 (52%), Positives = 76/113 (67%), Gaps = 1/113 (0%)
Query: 129 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQC 188
++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I R +RNRCQ C
Sbjct: 15 IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHC 73
Query: 189 RFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSP 241
R +KCL+VGMSRDAV+FGR+ K+++ + AE+Q + Q P E P
Sbjct: 74 RLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP 126
>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
Length = 556
Score = 128 bits (321), Expect = 2e-29
Identities = 66/146 (45%), Positives = 86/146 (58%), Gaps = 10/146 (6%)
Query: 96 NGSPPGSLQVAMEDSSRVSPSKSTSNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGF 155
NG PP S ++ V + I ++ CK+CGD +SG HYGV CEGCKGF
Sbjct: 79 NGKPPYS----QKEDKEVQTGYMNAQIE-----IIPCKICGDKSSGIHYGVITCEGCKGF 129
Query: 156 FRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQR 215
FRRS Q N Y C + +NC I R +RNRCQ CR +KCL+VGMSRDAV+FGR+ K+++
Sbjct: 130 FRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDS 188
Query: 216 MLAEMQSAMNLANNQLSSQCPLETSP 241
+ AE+Q + Q P E P
Sbjct: 189 LYAEVQKHRMQQQQRDHQQQPGEAEP 214
Score = 128 bits (321), Expect = 2e-29
Identities = 70/176 (39%), Positives = 112/176 (63%), Gaps = 2/176 (1%)
Query: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
+W+ ++ T A++ VVEFAK I GF +L Q+DQ+ LLKAG+ EV+ +R F+ ++ T
Sbjct: 352 MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNT 411
Query: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
V F + S ++G D +S +F+F + L S+ LTE+E+ LF+A VL+SADRS ++
Sbjct: 412 VYFDGKYA-SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ 470
Query: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610
+E+LQ+ + AL+ ++ KN E TKL+ K+ LR L H+EKL++F+
Sbjct: 471 EKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFK 525
>gi|194294519 nuclear receptor subfamily 1, group H, member 3
isoform c [Homo sapiens]
Length = 402
Score = 126 bits (316), Expect = 7e-29
Identities = 66/194 (34%), Positives = 115/194 (59%), Gaps = 3/194 (1%)
Query: 419 PMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFE 478
PM PH R R Q+ + F+ +V+E+V+FAK +PGF LS+ DQ+ LLK E
Sbjct: 194 PMAPDPHSREAR--QQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIE 251
Query: 479 VLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMG-DLLSAMFDFSEKLNSLALTEEEL 537
V+++ + +N +++ FL +Y+ ++ G+ + ++ +F+FS +N L L + E
Sbjct: 252 VMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEF 311
Query: 538 GLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRT 597
L A+ + SADR +++ VE+LQ T + AL A V + P + F ++L+KL LRT
Sbjct: 312 ALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRT 371
Query: 598 LNNMHSEKLLSFRV 611
L+++HSE++ + R+
Sbjct: 372 LSSVHSEQVFALRL 385
Score = 87.0 bits (214), Expect = 5e-17
Identities = 58/181 (32%), Positives = 79/181 (43%), Gaps = 40/181 (22%)
Query: 131 LCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRF 190
LC VCGD ASGFHY V +CEGCKGFFRRS+ + Y C +C + R +CQ+CR
Sbjct: 52 LCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHY-ICHSGGHCPMDTYMRRKCQECRL 110
Query: 191 KKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPTPGPM 250
+KC GM + V L+E Q + Q Q H T P
Sbjct: 111 RKCRQAGMREECV-------------LSEEQIRLKKLKRQEEEQA--------HATSLPP 149
Query: 251 GPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDKLGSS 310
S PP Q+ P SP +E +++ + +R F+ D+L +
Sbjct: 150 RASSPP---------------QILPQLSPEQLGMIEKLVAAQQQCNRRSFS---DRLRVT 191
Query: 311 P 311
P
Sbjct: 192 P 192
>gi|194294517 nuclear receptor subfamily 1, group H, member 3
isoform a [Homo sapiens]
Length = 447
Score = 126 bits (316), Expect = 7e-29
Identities = 66/194 (34%), Positives = 115/194 (59%), Gaps = 3/194 (1%)
Query: 419 PMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFE 478
PM PH R R Q+ + F+ +V+E+V+FAK +PGF LS+ DQ+ LLK E
Sbjct: 239 PMAPDPHSREAR--QQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIE 296
Query: 479 VLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMG-DLLSAMFDFSEKLNSLALTEEEL 537
V+++ + +N +++ FL +Y+ ++ G+ + ++ +F+FS +N L L + E
Sbjct: 297 VMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEF 356
Query: 538 GLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRT 597
L A+ + SADR +++ VE+LQ T + AL A V + P + F ++L+KL LRT
Sbjct: 357 ALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRT 416
Query: 598 LNNMHSEKLLSFRV 611
L+++HSE++ + R+
Sbjct: 417 LSSVHSEQVFALRL 430
Score = 87.0 bits (214), Expect = 5e-17
Identities = 58/181 (32%), Positives = 79/181 (43%), Gaps = 40/181 (22%)
Query: 131 LCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRF 190
LC VCGD ASGFHY V +CEGCKGFFRRS+ + Y C +C + R +CQ+CR
Sbjct: 97 LCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHY-ICHSGGHCPMDTYMRRKCQECRL 155
Query: 191 KKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPTPGPM 250
+KC GM + V L+E Q + Q Q H T P
Sbjct: 156 RKCRQAGMREECV-------------LSEEQIRLKKLKRQEEEQA--------HATSLPP 194
Query: 251 GPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVEDVISQVARAHREIFTYAHDKLGSS 310
S PP Q+ P SP +E +++ + +R F+ D+L +
Sbjct: 195 RASSPP---------------QILPQLSPEQLGMIEKLVAAQQQCNRRSFS---DRLRVT 236
Query: 311 P 311
P
Sbjct: 237 P 237
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 123 bits (308), Expect = 6e-28
Identities = 59/178 (33%), Positives = 106/178 (59%)
Query: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
+W+ FS T + ++VEFAK +PGF L+ DQ+TLLKA ++L++R + + + T
Sbjct: 217 LWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDT 276
Query: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
+ F T + ++ G G L +F F+ +L L + + E GL +A+ L+ DR +E
Sbjct: 277 MTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLE 336
Query: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVD 612
V++LQE LL AL+ + K RP + F K+L+K+ DLR+++ +E++++ +++
Sbjct: 337 EPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKME 394
Score = 105 bits (263), Expect = 9e-23
Identities = 47/82 (57%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Query: 132 CKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFK 191
C VC D +SG+HYGV ACEGCKGFFRRSIQ+N+ Y C +++NC I ++ RNRCQ CR +
Sbjct: 81 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIY-TCHRDKNCVINKVTRNRCQYCRLQ 139
Query: 192 KCLSVGMSRDAVRFGRIPKREK 213
KC VGMS+++VR R K+++
Sbjct: 140 KCFEVGMSKESVRNDRNKKKKE 161
>gi|7706625 retinoic acid receptor, beta isoform 2 [Homo sapiens]
Length = 336
Score = 123 bits (308), Expect = 6e-28
Identities = 59/178 (33%), Positives = 106/178 (59%)
Query: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
+W+ FS T + ++VEFAK +PGF L+ DQ+TLLKA ++L++R + + + T
Sbjct: 105 LWDKFSELATKCIIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDT 164
Query: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
+ F T + ++ G G L +F F+ +L L + + E GL +A+ L+ DR +E
Sbjct: 165 MTFSDGLTLNRTQMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLE 224
Query: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVD 612
V++LQE LL AL+ + K RP + F K+L+K+ DLR+++ +E++++ +++
Sbjct: 225 EPTKVDKLQEPLLEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKME 282
Score = 53.1 bits (126), Expect = 7e-07
Identities = 21/45 (46%), Positives = 33/45 (73%)
Query: 169 CLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREK 213
C +++NC I ++ RNRCQ CR +KC VGMS+++VR R K+++
Sbjct: 5 CHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKE 49
>gi|223718070 retinoic acid receptor, alpha isoform 4 [Homo sapiens]
Length = 365
Score = 121 bits (303), Expect = 2e-27
Identities = 60/179 (33%), Positives = 104/179 (58%)
Query: 434 EIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQ 493
++W+ FS T + + VEFAK +PGF L+ DQ+TLLKA ++L++R + + +
Sbjct: 126 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 185
Query: 494 TVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGM 553
T+ F T + ++ G G L +F F+ +L L + + E GL +A+ L+ DR +
Sbjct: 186 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 245
Query: 554 ENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVD 612
E V+ LQE LL AL+ V K RP F K+L+K+ DLR+++ +E++++ +++
Sbjct: 246 EQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKME 304
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 121 bits (303), Expect = 2e-27
Identities = 60/179 (33%), Positives = 104/179 (58%)
Query: 434 EIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQ 493
++W+ FS T + + VEFAK +PGF L+ DQ+TLLKA ++L++R + + +
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282
Query: 494 TVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGM 553
T+ F T + ++ G G L +F F+ +L L + + E GL +A+ L+ DR +
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 342
Query: 554 ENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVD 612
E V+ LQE LL AL+ V K RP F K+L+K+ DLR+++ +E++++ +++
Sbjct: 343 EQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKME 401
Score = 110 bits (274), Expect = 5e-24
Identities = 58/143 (40%), Positives = 84/143 (58%), Gaps = 4/143 (2%)
Query: 72 PPSLSDDGSPSSSSSSSSSSS-SFYNGSPPGSLQVAMEDSSRVSPSKSTSNITKLNGMVL 130
PP L P + ++ S Y+ P +++ S + PS + L +
Sbjct: 29 PPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSP--PPLPRIYK 86
Query: 131 LCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRF 190
C VC D +SG+HYGV ACEGCKGFFRRSIQ+N+ Y C +++NC I ++ RNRCQ CR
Sbjct: 87 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVY-TCHRDKNCIINKVTRNRCQYCRL 145
Query: 191 KKCLSVGMSRDAVRFGRIPKREK 213
+KC VGMS+++VR R K+++
Sbjct: 146 QKCFEVGMSKESVRNDRNKKKKE 168
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 121 bits (303), Expect = 2e-27
Identities = 60/179 (33%), Positives = 104/179 (58%)
Query: 434 EIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQ 493
++W+ FS T + + VEFAK +PGF L+ DQ+TLLKA ++L++R + + +
Sbjct: 218 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 277
Query: 494 TVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGM 553
T+ F T + ++ G G L +F F+ +L L + + E GL +A+ L+ DR +
Sbjct: 278 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 337
Query: 554 ENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVD 612
E V+ LQE LL AL+ V K RP F K+L+K+ DLR+++ +E++++ +++
Sbjct: 338 EQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKME 396
Score = 112 bits (279), Expect = 1e-24
Identities = 59/139 (42%), Positives = 85/139 (61%), Gaps = 4/139 (2%)
Query: 75 LSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTSNITKLNGMVLLCKV 134
L + G P+ S+ + +NGS S++ S + PS + L + C V
Sbjct: 29 LPEKGLPAPGPYSTPLRTPLWNGSNH-SIETQSSSSEEIVPSPPSP--PPLPRIYKPCFV 85
Query: 135 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCL 194
C D +SG+HYGV ACEGCKGFFRRSIQ+N+ Y C +++NC I ++ RNRCQ CR +KC
Sbjct: 86 CQDKSSGYHYGVSACEGCKGFFRRSIQKNMVY-TCHRDKNCIINKVTRNRCQYCRLQKCF 144
Query: 195 SVGMSRDAVRFGRIPKREK 213
VGMS+++VR R K+++
Sbjct: 145 EVGMSKESVRNDRNKKKKE 163
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 121 bits (303), Expect = 2e-27
Identities = 60/179 (33%), Positives = 104/179 (58%)
Query: 434 EIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQ 493
++W+ FS T + + VEFAK +PGF L+ DQ+TLLKA ++L++R + + +
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282
Query: 494 TVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGM 553
T+ F T + ++ G G L +F F+ +L L + + E GL +A+ L+ DR +
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 342
Query: 554 ENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVD 612
E V+ LQE LL AL+ V K RP F K+L+K+ DLR+++ +E++++ +++
Sbjct: 343 EQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKME 401
Score = 110 bits (274), Expect = 5e-24
Identities = 58/143 (40%), Positives = 84/143 (58%), Gaps = 4/143 (2%)
Query: 72 PPSLSDDGSPSSSSSSSSSSS-SFYNGSPPGSLQVAMEDSSRVSPSKSTSNITKLNGMVL 130
PP L P + ++ S Y+ P +++ S + PS + L +
Sbjct: 29 PPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSP--PPLPRIYK 86
Query: 131 LCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRF 190
C VC D +SG+HYGV ACEGCKGFFRRSIQ+N+ Y C +++NC I ++ RNRCQ CR
Sbjct: 87 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVY-TCHRDKNCIINKVTRNRCQYCRL 145
Query: 191 KKCLSVGMSRDAVRFGRIPKREK 213
+KC VGMS+++VR R K+++
Sbjct: 146 QKCFEVGMSKESVRNDRNKKKKE 168
>gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Homo
sapiens]
Length = 461
Score = 120 bits (302), Expect = 3e-27
Identities = 65/194 (33%), Positives = 111/194 (57%), Gaps = 3/194 (1%)
Query: 419 PMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFE 478
P+ P R R Q+ + F+ +V+E+V+FAK +PGF L + DQ+ LLKA T E
Sbjct: 253 PLGADPQSRDAR--QQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIE 310
Query: 479 VLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMG-DLLSAMFDFSEKLNSLALTEEEL 537
++++ A +N + + + FL TYS + G+ + ++ +F+FS + L L + E
Sbjct: 311 IMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEY 370
Query: 538 GLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRT 597
L A+ + SADR ++ VE LQ+ + AL + RP + RF ++L+KL LRT
Sbjct: 371 ALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRT 430
Query: 598 LNNMHSEKLLSFRV 611
L+++HSE++ + R+
Sbjct: 431 LSSVHSEQVFALRL 444
Score = 94.0 bits (232), Expect = 4e-19
Identities = 65/208 (31%), Positives = 96/208 (46%), Gaps = 19/208 (9%)
Query: 37 SNGSFQSLTQGCPTYFPPSPTGSLTQDPARSFGSIP-PSLSDDGSPSSSSSSSSSSSSFY 95
S+ + SL P PP P + + G P P D P + +SS+ S+ +
Sbjct: 2 SSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWV 61
Query: 96 NGSPPGSLQVAMEDSSRVSPSKSTSNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGF 155
P E+ R + K+ G L C+VCGD ASGFHY V +CEGCKGF
Sbjct: 62 IPDPE-------EEPER---KRKKGPAPKMLGHEL-CRVCGDKASGFHYNVLSCEGCKGF 110
Query: 156 FRRS-IQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGM------SRDAVRFGRI 208
FRRS ++ + C C + R +CQQCR +KC GM S + +R +I
Sbjct: 111 FRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKI 170
Query: 209 PKREKQRMLAEMQSAMNLANNQLSSQCP 236
K+++Q ++ QS + + S+ P
Sbjct: 171 RKQQQQESQSQSQSPVGPQGSSSSASGP 198
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 120 bits (301), Expect = 4e-27
Identities = 60/178 (33%), Positives = 103/178 (57%)
Query: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
+W+ FS T + ++VEFAK +PGF LS DQ+TLLKA ++LM+R + + + T
Sbjct: 215 LWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDT 274
Query: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
+ F T + ++ G G L +F F+ +L L + + E GL +A+ L+ DR +E
Sbjct: 275 MTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLE 334
Query: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVD 612
V++LQE LL ALR + RP + F ++L+K+ DLR ++ +E+ ++ +++
Sbjct: 335 EPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKME 392
Score = 107 bits (266), Expect = 4e-23
Identities = 47/82 (57%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Query: 132 CKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFK 191
C VC D +SG+HYGV +CEGCKGFFRRSIQ+N+ Y C +++NC I ++ RNRCQ CR +
Sbjct: 79 CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVY-TCHRDKNCIINKVTRNRCQYCRLQ 137
Query: 192 KCLSVGMSRDAVRFGRIPKREK 213
KC VGMS++AVR R K+++
Sbjct: 138 KCFEVGMSKEAVRNDRNKKKKE 159
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 120 bits (301), Expect = 4e-27
Identities = 60/178 (33%), Positives = 103/178 (57%)
Query: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
+W+ FS T + ++VEFAK +PGF LS DQ+TLLKA ++LM+R + + + T
Sbjct: 226 LWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDT 285
Query: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
+ F T + ++ G G L +F F+ +L L + + E GL +A+ L+ DR +E
Sbjct: 286 MTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLE 345
Query: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRVD 612
V++LQE LL ALR + RP + F ++L+K+ DLR ++ +E+ ++ +++
Sbjct: 346 EPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKME 403
Score = 107 bits (266), Expect = 4e-23
Identities = 47/82 (57%), Positives = 63/82 (76%), Gaps = 1/82 (1%)
Query: 132 CKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFK 191
C VC D +SG+HYGV +CEGCKGFFRRSIQ+N+ Y C +++NC I ++ RNRCQ CR +
Sbjct: 90 CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVY-TCHRDKNCIINKVTRNRCQYCRLQ 148
Query: 192 KCLSVGMSRDAVRFGRIPKREK 213
KC VGMS++AVR R K+++
Sbjct: 149 KCFEVGMSKEAVRNDRNKKKKE 170
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 114 bits (285), Expect = 3e-25
Identities = 84/247 (34%), Positives = 122/247 (49%), Gaps = 31/247 (12%)
Query: 24 PSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTG----SLTQDPARSFGSIPPSLSDDG 79
P SP L+S S S G P SP G S+ P F + P LS
Sbjct: 39 PGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPM 98
Query: 80 SPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKSTSNITKLNGMVLLCKVCGDVA 139
+P SSS PP L ++ + PS + ++ TK +C +CGD +
Sbjct: 99 NPVSSSEDIK---------PPLGLNGVLKVPAH--PSGNMASFTKH-----ICAICGDRS 142
Query: 140 SGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQCRFKKCLSVGMS 199
SG HYGV++CEGCKGFF+R++++++ Y C N++C I + RNRCQ CR++KCL++GM
Sbjct: 143 SGKHYGVYSCEGCKGFFKRTVRKDLTY-TCRDNKDCLIDKRQRNRCQYCRYQKCLAMGMK 201
Query: 200 RDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSPTQHPTPGP-------MGP 252
R+AV+ R +R K R E++S + AN + + LE P + P
Sbjct: 202 REAVQEER--QRGKDRNENEVESTSS-ANEDMPVERILEAELAVEPKTETYVEANMGLNP 258
Query: 253 SPPPAPV 259
S P PV
Sbjct: 259 SSPNDPV 265
Score = 82.0 bits (201), Expect = 1e-15
Identities = 51/163 (31%), Positives = 82/163 (50%), Gaps = 1/163 (0%)
Query: 450 VVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELG 509
+VE+AK IP F +L DQV LL+AG E+L+ F+ ++ +
Sbjct: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338
Query: 510 AMGMGDLLSAMF-DFSEKLNSLALTEEELGLFTAVVLVSADRSGMENSASVEQLQETLLR 568
+ G+G + + + K+ + + + ELG A+VL + D G+ N A VE L+E +
Sbjct: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398
Query: 569 ALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFRV 611
+L A P + RF KLLL+LP LR++ E L F++
Sbjct: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKL 441
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,866,264
Number of Sequences: 37866
Number of extensions: 1656794
Number of successful extensions: 24405
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 346
Number of HSP's successfully gapped in prelim test: 762
Number of HSP's that attempted gapping in prelim test: 15120
Number of HSP's gapped (non-prelim): 6632
length of query: 614
length of database: 18,247,518
effective HSP length: 108
effective length of query: 506
effective length of database: 14,157,990
effective search space: 7163942940
effective search space used: 7163942940
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.