Guide to the Human Genome
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Name: HNF1A Sequence: fasta or formatted (631aa) NCBI GI: 134304844
Description:

hepatic nuclear factor-1-alpha

Referenced in:

Homeobox and Related Proteins
Liver

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.6         48           2
 C cysteine            0.5          3           1
 D aspartate           2.2         14           3
 E glutamate           6.8         43           2
 F phenylalanine       1.7         11           1
 G glycine             7.6         48           3
 H histidine           3.5         22           1
 I isoleucine          2.2         14           1
 K lysine              3.5         22           2
 L leucine            11.3         71           2
 M methionine          1.9         12           1
 N asparagine          2.9         18           1
 P proline             9.5         60           3
 Q glutamine           7.9         50           2
 R arginine            3.2         20           2
 S serine             11.6         73           4
 T threonine           8.1         51           2
 V valine              5.5         35           2
 W tryptophan          0.6          4           1
 Y tyrosine            1.9         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hepatic nuclear factor-1-alpha 
HNF1B                 0.422   transcription factor 2 
HMBOX1                0.041   homeobox containing 1 
HMBOX1                0.041   homeobox containing 1 
MUC6                  0.032   mucin 6, gastric 
RPRD2                 0.028   Regulation of nuclear pre-mRNA domain containing 2 ...
SRCAP                 0.024   Snf2-related CBP activator protein 
MUC2                  0.024   mucin 2 precursor 
MUC4                  0.024   mucin 4 isoform a 
MUC12                 0.024   PREDICTED: mucin 12 
ATN1                  0.023   atrophin-1 
ATN1                  0.023   atrophin-1 
FLJ22184              0.022   PREDICTED: hypothetical protein FLJ22184 
SAP130                0.022   Sin3A-associated protein, 130kDa isoform b 
SAP130                0.022   Sin3A-associated protein, 130kDa isoform a 
MUC5B                 0.022   mucin 5, subtype B, tracheobronchial 
CIC                   0.022   capicua homolog 
WNK1                  0.022   WNK lysine deficient protein kinase 1 
LOC100130716          0.020   PREDICTED: similar to Mucin-12 
RERE                  0.020   atrophin-1 like protein isoform b 
RERE                  0.020   atrophin-1 like protein isoform a 
RERE                  0.020   atrophin-1 like protein isoform a 
KIAA0754              0.020   hypothetical protein LOC643314 
ZNF469                0.020   zinc finger protein 469 
LOC100133714          0.019   PREDICTED: similar to Mucin-12, partial 
MUC12                 0.019   PREDICTED: mucin 12 
LOC100130716          0.019   PREDICTED: similar to mucin 11 
MUC3A                 0.019   PREDICTED: mucin 3A, intestinal 
LOC284297             0.018   hypothetical protein LOC284297 
LOC100131514          0.018   PREDICTED: similar to hCG1747327, partial 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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