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Search of human proteins with 134288906
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134288906 tripartite motif-containing 67 [Homo sapiens]
(783 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134288906 tripartite motif-containing 67 [Homo sapiens] 1619 0.0
gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens] 978 0.0
gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens] 692 0.0
gi|223890259 midline 2 isoform 2 [Homo sapiens] 199 8e-51
gi|223890257 midline 2 isoform 1 [Homo sapiens] 189 9e-48
gi|148833499 midline 1 [Homo sapiens] 189 9e-48
gi|4557753 midline 1 [Homo sapiens] 189 9e-48
gi|15451852 midline 1 [Homo sapiens] 189 9e-48
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 165 1e-40
gi|47174859 tripartite motif-containing 46 [Homo sapiens] 159 9e-39
gi|89886468 fibronectin type III and SPRY domain containing 1-li... 109 9e-24
gi|223718222 fibronectin type III and SPRY domain containing 1-l... 108 2e-23
gi|13236585 fibronectin type III and SPRY domain containing 1 [H... 97 6e-20
gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens] 97 8e-20
gi|19924163 muscle specific ring finger protein 1 [Homo sapiens] 94 6e-19
gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens] 78 4e-14
gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens] 78 4e-14
gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens] 78 4e-14
gi|84993742 tripartite motif-containing 71 [Homo sapiens] 77 5e-14
gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens] 77 6e-14
gi|55741632 fibronectin type III and SPRY domain containing 2 [H... 76 1e-13
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 70 6e-12
gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens] 69 2e-11
gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens] 69 2e-11
gi|32454739 tripartite motif-containing 3 [Homo sapiens] 59 2e-08
gi|32454737 tripartite motif-containing 3 [Homo sapiens] 59 2e-08
gi|122937424 one cut homeobox 3 [Homo sapiens] 57 7e-08
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 57 9e-08
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 57 9e-08
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 57 9e-08
>gi|134288906 tripartite motif-containing 67 [Homo sapiens]
Length = 783
Score = 1619 bits (4193), Expect = 0.0
Identities = 783/783 (100%), Positives = 783/783 (100%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG 60
MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG
Sbjct: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG 60
Query: 61 AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPSLK 120
AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPSLK
Sbjct: 61 AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPSLK 120
Query: 121 SPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRGLRGFQRNR 180
SPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRGLRGFQRNR
Sbjct: 121 SPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRGLRGFQRNR 180
Query: 181 LLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHP 240
LLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHP
Sbjct: 181 LLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHP 240
Query: 241 SRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKF 300
SRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKF
Sbjct: 241 SRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKF 300
Query: 301 PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD 360
PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD
Sbjct: 301 PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD 360
Query: 361 KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL 420
KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL
Sbjct: 361 KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL 420
Query: 421 KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE 480
KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE
Sbjct: 421 KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE 480
Query: 481 PKVSAEFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFT 540
PKVSAEFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFT
Sbjct: 481 PKVSAEFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFT 540
Query: 541 HSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTV 600
HSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTV
Sbjct: 541 HSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTV 600
Query: 601 VLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDRY 660
VLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDRY
Sbjct: 601 VLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDRY 660
Query: 661 DNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVG 720
DNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVG
Sbjct: 661 DNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVG 720
Query: 721 VLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLEVPTNLGRPKL 780
VLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLEVPTNLGRPKL
Sbjct: 721 VLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLEVPTNLGRPKL 780
Query: 781 SGN 783
SGN
Sbjct: 781 SGN 783
>gi|190341104 tripartite motif protein 9 isoform 1 [Homo sapiens]
Length = 710
Score = 978 bits (2528), Expect = 0.0
Identities = 493/782 (63%), Positives = 570/782 (72%), Gaps = 95/782 (12%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG 60
MEEELKCPVCGS +REPIILPCSHN+C CAR I VQTP+ E PQ
Sbjct: 4 MEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESES--PQ------------- 48
Query: 61 AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSY----- 115
H AA G+G S L DK+SLYSE DSGYGSY
Sbjct: 49 -------SHRAA------GSGVSDYDYLD---------LDKMSLYSEADSGYGSYGGFAS 86
Query: 116 ---TPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRG 172
TP KSPNGVRV P PP + + A +S ITCPQCHRS LD RG
Sbjct: 87 APTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV-----PRNSCITCPQCHRSLILDDRG 141
Query: 173 LRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCS 232
LRGF +NR+LE ++ RYQQ + AA CQLC++ P E A +CEQCDV YC
Sbjct: 142 LRGFPKNRVLEGVIDRYQQSK---------AAALKCQLCEKAPKE-ATVMCEQCDVFYCD 191
Query: 233 ACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGAT 292
C+L+CHP RGP AKHRLV P AQG S
Sbjct: 192 PCRLRCHPPRGPLAKHRLVPP-----------------AQGRVSRR-------------- 220
Query: 293 GGSTARKFPTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLS 352
+ RK TC +HE+EN+SMYCV C+ PVCY CLEEG+H+ HEVK LGAMWK HK+QLS
Sbjct: 221 --LSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLS 278
Query: 353 QALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKV 412
QALNG+SD+AKEAKEFLVQL+N++QQIQEN +++EACLVAQCDAL+DAL R+KA+LL +V
Sbjct: 279 QALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARV 338
Query: 413 TKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQE 472
KE EHKLK+V DQI+HCT+KLRQ+TGLMEYCLEVIKENDPSGFLQISDALI+RV ++++
Sbjct: 339 NKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTED 398
Query: 473 QWVKGALEPKVSAEFDLTLDSEPLLQAIHQLDFIQMKCR--VPPVPLLQLEKCCTRNNSV 530
QW KG L P+++ +FDL+LD+ PLLQ+IHQLDF+Q+K VP P+LQLE+CCT NNS
Sbjct: 399 QWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSA 458
Query: 531 TLAWRMPPFTHSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNS 590
TL+W+ PP + P DGYILELDDG GGQFREVYVGKET+CT+DGLHFNSTYNARVKAFN
Sbjct: 459 TLSWKQPPLSTVPADGYILELDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNK 518
Query: 591 SGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSYDDRVVLGTAAFSKGV 650
+GV PYSKT+VLQTS+VAWF FDP S H DIILSNDN T TCSSYDDRVVLG FSKG+
Sbjct: 519 TGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIILSNDNLTVTCSSYDDRVVLGKTGFSKGI 578
Query: 651 HYWELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTE 710
HYWEL VDRYDNHPDPAFGVAR V+KD+MLGKDDKAWAMYVDNNRSWFMH NSHTNRTE
Sbjct: 579 HYWELTVDRYDNHPDPAFGVARMDVMKDVMLGKDDKAWAMYVDNNRSWFMHNNSHTNRTE 638
Query: 711 GGVCKGATVGVLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLE 770
GG+ KGAT+GVLLDLN+ LTFFIN +QQGP AF +V+G+F PA+SLNRNVQVTLHTGL
Sbjct: 639 GGITKGATIGVLLDLNRKNLTFFINDEQQGPIAFDNVEGLFFPAVSLNRNVQVTLHTGLP 698
Query: 771 VP 772
VP
Sbjct: 699 VP 700
>gi|16519559 tripartite motif protein 9 isoform 2 [Homo sapiens]
Length = 550
Score = 692 bits (1785), Expect = 0.0
Identities = 359/616 (58%), Positives = 425/616 (68%), Gaps = 95/616 (15%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG 60
MEEELKCPVCGS +REPIILPCSHN+C CAR I VQTP+ E PQ
Sbjct: 4 MEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPESES--PQ------------- 48
Query: 61 AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSY----- 115
H AA G+G S L DK+SLYSE DSGYGSY
Sbjct: 49 -------SHRAA------GSGVSDYDYLD---------LDKMSLYSEADSGYGSYGGFAS 86
Query: 116 ---TPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRG 172
TP KSPNGVRV P PP + + A +S ITCPQCHRS LD RG
Sbjct: 87 APTTPCQKSPNGVRVFPPAMPPPATHLSPALAPV-----PRNSCITCPQCHRSLILDDRG 141
Query: 173 LRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCS 232
LRGF +NR+LE ++ RYQQ + AA CQLC++ P E A +CEQCDV YC
Sbjct: 142 LRGFPKNRVLEGVIDRYQQSK---------AAALKCQLCEKAPKE-ATVMCEQCDVFYCD 191
Query: 233 ACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGAT 292
C+L+CHP RGP AKHRLV P AQG S
Sbjct: 192 PCRLRCHPPRGPLAKHRLVPP-----------------AQGRVSRR-------------- 220
Query: 293 GGSTARKFPTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLS 352
+ RK TC +HE+EN+SMYCV C+ PVCY CLEEG+H+ HEVK LGAMWK HK+QLS
Sbjct: 221 --LSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQLS 278
Query: 353 QALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKV 412
QALNG+SD+AKEAKEFLVQL+N++QQIQEN +++EACLVAQCDAL+DAL R+KA+LL +V
Sbjct: 279 QALNGLSDRAKEAKEFLVQLRNMVQQIQENSVEFEACLVAQCDALIDALNRRKAQLLARV 338
Query: 413 TKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQE 472
KE EHKLK+V DQI+HCT+KLRQ+TGLMEYCLEVIKENDPSGFLQISDALI+RV ++++
Sbjct: 339 NKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRRVHLTED 398
Query: 473 QWVKGALEPKVSAEFDLTLDSEPLLQAIHQLDFIQMKCR--VPPVPLLQLEKCCTRNNSV 530
QW KG L P+++ +FDL+LD+ PLLQ+IHQLDF+Q+K VP P+LQLE+CCT NNS
Sbjct: 399 QWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEECCTHNNSA 458
Query: 531 TLAWRMPPFTHSPVDGYILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNS 590
TL+W+ PP + P DGYILELDDG GGQFREVYVGKET+CT+DGLHFNSTYNARVKAFN
Sbjct: 459 TLSWKQPPLSTVPADGYILELDDGNGGQFREVYVGKETMCTVDGLHFNSTYNARVKAFNK 518
Query: 591 SGVGPYSKTVVLQTSD 606
+GV PYSKT+VLQTS+
Sbjct: 519 TGVSPYSKTLVLQTSE 534
>gi|223890259 midline 2 isoform 2 [Homo sapiens]
Length = 705
Score = 199 bits (506), Expect = 8e-51
Identities = 165/641 (25%), Positives = 273/641 (42%), Gaps = 114/641 (17%)
Query: 145 AACSSLSSSS--SSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQG---------- 192
++CSS S ++ CP C SL+HRGL G +RN L+ I+ R+Q+
Sbjct: 60 SSCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE 119
Query: 193 ----RGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKH 248
R P T+ ++ CQ C++ PP A C C+V YC C HP++ PF H
Sbjct: 120 SRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSH 179
Query: 249 RLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEM 308
RLV+P P T + TC +HE
Sbjct: 180 RLVEPVP---------------------------------------DTHLRGITCLDHEN 200
Query: 309 ENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEF 368
E +MYCVS +C LC GRH H+V L +++ K L L + + E +
Sbjct: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
Query: 369 LVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQIN 428
+ +L I QQ++ N +EA L+ +CD LV+ + ++K + K+ + + KL+ + Q+
Sbjct: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
Query: 429 HCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVS---A 485
+C L +ST L+ ++KEND + FLQ + + +RV ++ L P ++ A
Sbjct: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATAS--SQVLIPDINFNDA 378
Query: 486 EFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVD 545
+ LD + + LD++ P P ++ E C ++++T+ W +
Sbjct: 379 FENFALDFSREKKLLEGLDYL----TAPNPPSIREELCTASHDTITVHWISD--DEFSIS 432
Query: 546 GYILELDDGAG-GQFREVYVG----------KETLCTIDGLHFNSTYNARVKAFNSSGVG 594
Y L+ G F +Y K+ T+ GL + Y VKA N +G
Sbjct: 433 SYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAG-S 491
Query: 595 PYSKTVVLQTSDVAWFTFDPNSGHRDIILSND------NQTATCSSYDDRVVLGTAAF-- 646
S+ L+T+ F DP H+ + +SND ++++ S+ GT +
Sbjct: 492 RNSEPTRLKTNSQP-FKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGA 550
Query: 647 ------SKGVHYWELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWA--------MYV 692
G HYWE+ + + A G+A S K+ +GK+ +W +
Sbjct: 551 AGNIFIDSGCHYWEVVMGSSTWY---AIGIAYKSAPKNEWIGKNASSWVFSRCNSNFVVR 607
Query: 693 DNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLTFF 733
NN+ + H R +GVLLD + + L+F+
Sbjct: 608 HNNKEMLVDVPPHLKR----------LGVLLDYDNNMLSFY 638
Score = 51.2 bits (121), Expect = 4e-06
Identities = 18/38 (47%), Positives = 27/38 (71%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQT 38
+E EL CP+C LF +P++LPC+H++C CA I V +
Sbjct: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSS 61
>gi|223890257 midline 2 isoform 1 [Homo sapiens]
Length = 735
Score = 189 bits (480), Expect = 9e-48
Identities = 166/671 (24%), Positives = 275/671 (40%), Gaps = 144/671 (21%)
Query: 145 AACSSLSSSS--SSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQG---------- 192
++CSS S ++ CP C SL+HRGL G +RN L+ I+ R+Q+
Sbjct: 60 SSCSSGESIEPITAFQCPTCRYVISLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSE 119
Query: 193 ----RGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKH 248
R P T+ ++ CQ C++ PP A C C+V YC C HP++ PF H
Sbjct: 120 SRRERTYRPTTAMSSERIACQFCEQDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSH 179
Query: 249 RLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEM 308
RLV+P P T + TC +HE
Sbjct: 180 RLVEPVP---------------------------------------DTHLRGITCLDHEN 200
Query: 309 ENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEF 368
E +MYCVS +C LC GRH H+V L +++ K L L + + E +
Sbjct: 201 EKVNMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQ 260
Query: 369 LVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQIN 428
+ +L I QQ++ N +EA L+ +CD LV+ + ++K + K+ + + KL+ + Q+
Sbjct: 261 MAKLIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVA 320
Query: 429 HCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVS---A 485
+C L +ST L+ ++KEND + FLQ + + +RV ++ L P ++ A
Sbjct: 321 NCRQCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATAS--SQVLIPDINFNDA 378
Query: 486 EFDLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVD 545
+ LD + + LD++ P P ++ E C ++++T+ W +
Sbjct: 379 FENFALDFSREKKLLEGLDYL----TAPNPPSIREELCTASHDTITVHWISD--DEFSIS 432
Query: 546 GYILELDDGAG------------GQFREVYVGKETLC----------------------- 570
Y L+ G G + E+ KE +
Sbjct: 433 SYELQYTIFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLAGAPRGLYNSVDSWMIVPN 492
Query: 571 ------TIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILS 624
T+ GL + Y VKA N +G S+ L+T+ F DP H+ + +S
Sbjct: 493 IKQNHYTVHGLQSGTRYIFIVKAINQAG-SRNSEPTRLKTNSQP-FKLDPKMTHKKLKIS 550
Query: 625 ND------NQTATCSSYDDRVVLGTAAF--------SKGVHYWELHVDRYDNHPDPAFGV 670
ND ++++ S+ GT + G HYWE+ + + A G+
Sbjct: 551 NDGLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWY---AIGI 607
Query: 671 ARASVVKDMMLGKDDKAWA--------MYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVL 722
A S K+ +GK+ +W + NN+ + H R +GVL
Sbjct: 608 AYKSAPKNEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLKR----------LGVL 657
Query: 723 LDLNKHTLTFF 733
LD + + L+F+
Sbjct: 658 LDYDNNMLSFY 668
Score = 51.2 bits (121), Expect = 4e-06
Identities = 18/38 (47%), Positives = 27/38 (71%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQT 38
+E EL CP+C LF +P++LPC+H++C CA I V +
Sbjct: 24 LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSS 61
>gi|148833499 midline 1 [Homo sapiens]
Length = 667
Score = 189 bits (480), Expect = 9e-48
Identities = 158/620 (25%), Positives = 256/620 (41%), Gaps = 90/620 (14%)
Query: 153 SSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPG-------------- 198
S ++ CP C +L RGL G +RN L+ I+ R+Q+ + P
Sbjct: 50 SITAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDAN 109
Query: 199 TSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPP 258
T +A +CQ CD+ P + A C C+V YC C HP++ PF HRL++P P
Sbjct: 110 TMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPD-- 167
Query: 259 PPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEMENYSMYCVSC 318
S R C EHE E +MYCV+
Sbjct: 168 ------------------------------------SHIRGL-MCLEHEDEKVNMYCVTD 190
Query: 319 RTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQ 378
+C LC GRH H+V L + + K L L + + E + L +L Q
Sbjct: 191 DQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQH 250
Query: 379 IQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQST 438
++ N EA L +CD L++ + +++ + TK+ + + +L+ + QI +C + +S
Sbjct: 251 VEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSA 310
Query: 439 GLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEFD-LTLDSEPLL 497
L+ +KEND + FLQ + + +RV ++ E ++ FD LD
Sbjct: 311 SLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREK 370
Query: 498 QAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMP----------PFTHSPVDGY 547
+ + LD++ P P ++ E C +++T+ W +T
Sbjct: 371 KLLECLDYL----TAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQAN 426
Query: 548 ILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDV 607
++ L + A + K+ T+ GL + Y VKA N +G S+ L+T+
Sbjct: 427 VVSLCNSADSWMIVPNI-KQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQ 484
Query: 608 AWFTFDPNSGHRDIILSNDNQTA--------------TCSSYDDRVVLGTAAFSKGVHYW 653
F DP S HR + +S+DN T +S V G G HYW
Sbjct: 485 P-FKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYW 543
Query: 654 ELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGV 713
E+ + + A G+A S K +GK+ +WA+ NN +W + NS E
Sbjct: 544 EVVISGSTWY---AIGLAYKSAPKHEWIGKNSASWALCRCNN-NWVVRHNSKEIPIEPAP 599
Query: 714 CKGATVGVLLDLNKHTLTFF 733
VG+LLD + ++ F+
Sbjct: 600 -HLRRVGILLDYDNGSIAFY 618
Score = 50.4 bits (119), Expect = 6e-06
Identities = 18/36 (50%), Positives = 26/36 (72%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAV 36
+E EL CP+C LF +P++LPC+H++C CA I V
Sbjct: 4 LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILV 39
>gi|4557753 midline 1 [Homo sapiens]
Length = 667
Score = 189 bits (480), Expect = 9e-48
Identities = 158/620 (25%), Positives = 256/620 (41%), Gaps = 90/620 (14%)
Query: 153 SSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPG-------------- 198
S ++ CP C +L RGL G +RN L+ I+ R+Q+ + P
Sbjct: 50 SITAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDAN 109
Query: 199 TSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPP 258
T +A +CQ CD+ P + A C C+V YC C HP++ PF HRL++P P
Sbjct: 110 TMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPD-- 167
Query: 259 PPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEMENYSMYCVSC 318
S R C EHE E +MYCV+
Sbjct: 168 ------------------------------------SHIRGL-MCLEHEDEKVNMYCVTD 190
Query: 319 RTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQ 378
+C LC GRH H+V L + + K L L + + E + L +L Q
Sbjct: 191 DQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQH 250
Query: 379 IQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQST 438
++ N EA L +CD L++ + +++ + TK+ + + +L+ + QI +C + +S
Sbjct: 251 VEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSA 310
Query: 439 GLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEFD-LTLDSEPLL 497
L+ +KEND + FLQ + + +RV ++ E ++ FD LD
Sbjct: 311 SLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREK 370
Query: 498 QAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMP----------PFTHSPVDGY 547
+ + LD++ P P ++ E C +++T+ W +T
Sbjct: 371 KLLECLDYL----TAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQAN 426
Query: 548 ILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDV 607
++ L + A + K+ T+ GL + Y VKA N +G S+ L+T+
Sbjct: 427 VVSLCNSADSWMIVPNI-KQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQ 484
Query: 608 AWFTFDPNSGHRDIILSNDNQTA--------------TCSSYDDRVVLGTAAFSKGVHYW 653
F DP S HR + +S+DN T +S V G G HYW
Sbjct: 485 P-FKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYW 543
Query: 654 ELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGV 713
E+ + + A G+A S K +GK+ +WA+ NN +W + NS E
Sbjct: 544 EVVISGSTWY---AIGLAYKSAPKHEWIGKNSASWALCRCNN-NWVVRHNSKEIPIEPAP 599
Query: 714 CKGATVGVLLDLNKHTLTFF 733
VG+LLD + ++ F+
Sbjct: 600 -HLRRVGILLDYDNGSIAFY 618
Score = 50.4 bits (119), Expect = 6e-06
Identities = 18/36 (50%), Positives = 26/36 (72%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAV 36
+E EL CP+C LF +P++LPC+H++C CA I V
Sbjct: 4 LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILV 39
>gi|15451852 midline 1 [Homo sapiens]
Length = 667
Score = 189 bits (480), Expect = 9e-48
Identities = 158/620 (25%), Positives = 256/620 (41%), Gaps = 90/620 (14%)
Query: 153 SSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPG-------------- 198
S ++ CP C +L RGL G +RN L+ I+ R+Q+ + P
Sbjct: 50 SITAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDAN 109
Query: 199 TSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPP 258
T +A +CQ CD+ P + A C C+V YC C HP++ PF HRL++P P
Sbjct: 110 TMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPD-- 167
Query: 259 PPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEMENYSMYCVSC 318
S R C EHE E +MYCV+
Sbjct: 168 ------------------------------------SHIRGL-MCLEHEDEKVNMYCVTD 190
Query: 319 RTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQ 378
+C LC GRH H+V L + + K L L + + E + L +L Q
Sbjct: 191 DQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQH 250
Query: 379 IQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQST 438
++ N EA L +CD L++ + +++ + TK+ + + +L+ + QI +C + +S
Sbjct: 251 VEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSA 310
Query: 439 GLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEFD-LTLDSEPLL 497
L+ +KEND + FLQ + + +RV ++ E ++ FD LD
Sbjct: 311 SLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREK 370
Query: 498 QAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMP----------PFTHSPVDGY 547
+ + LD++ P P ++ E C +++T+ W +T
Sbjct: 371 KLLECLDYL----TAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQAN 426
Query: 548 ILELDDGAGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDV 607
++ L + A + K+ T+ GL + Y VKA N +G S+ L+T+
Sbjct: 427 VVSLCNSADSWMIVPNI-KQNHYTVHGLQSGTKYIFMVKAINQAG-SRSSEPGKLKTNSQ 484
Query: 608 AWFTFDPNSGHRDIILSNDNQTA--------------TCSSYDDRVVLGTAAFSKGVHYW 653
F DP S HR + +S+DN T +S V G G HYW
Sbjct: 485 P-FKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYW 543
Query: 654 ELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGV 713
E+ + + A G+A S K +GK+ +WA+ NN +W + NS E
Sbjct: 544 EVVISGSTWY---AIGLAYKSAPKHEWIGKNSASWALCRCNN-NWVVRHNSKEIPIEPAP 599
Query: 714 CKGATVGVLLDLNKHTLTFF 733
VG+LLD + ++ F+
Sbjct: 600 -HLRRVGILLDYDNGSIAFY 618
Score = 50.4 bits (119), Expect = 6e-06
Identities = 18/36 (50%), Positives = 26/36 (72%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAV 36
+E EL CP+C LF +P++LPC+H++C CA I V
Sbjct: 4 LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILV 39
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 165 bits (418), Expect = 1e-40
Identities = 138/541 (25%), Positives = 220/541 (40%), Gaps = 89/541 (16%)
Query: 148 SSLSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAI 207
+SL+ ++ CP C L RG+ G RN LE IV+RY+Q + AA +
Sbjct: 104 NSLTPRTTVFPCPGCEHDVDLGERGINGLFRNFTLETIVERYRQA-------ARAATAIM 156
Query: 208 CQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGP 267
C LC + PP+ + C C YC+ C HP A+H V P P
Sbjct: 157 CDLC-KPPPQESTKSCMDCSASYCNECFKIHHPWGTIKAQHEYVGPTTNFRP-------- 207
Query: 268 TGTAQGAPSGGGGCKSPGGAGAGATGGSTARKFPTCPEHEMENYSMYCVSCRTPVCYLCL 327
K CPEHE E +MYC CR PVC+LC
Sbjct: 208 -------------------------------KILMCPEHETERINMYCELCRRPVCHLCK 236
Query: 328 EEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYE 387
G HA H V + + +K K +LS+ ++ + K + K + +L ++++ + NG +
Sbjct: 237 LGGNHANHRVTTMSSAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAK 296
Query: 388 ACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEV 447
+ + L + L +K+ +L + ++ +L Q+ L ++ GL+ Y EV
Sbjct: 297 EEAITHFEKLFEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQ-GLLENNGLVGYAQEV 355
Query: 448 IKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEF-DLTLDSEPLLQAIHQLDFI 506
+KE D S F+Q + L R+Q + E + P F D +++ + + +L F
Sbjct: 356 LKETDQSCFVQTAKQLHLRIQKATES--LKSFRPAAQTSFEDYVVNTSKQTELLGELSFF 413
Query: 507 QMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVDGYILEL-----DDGAGGQFRE 561
VP + E+ N+ + W P D Y+LE DD E
Sbjct: 414 SSGIDVPEIN----EEQSKVYNNALINWHHP--EKDKADSYVLEYRKINRDDEMSWNEIE 467
Query: 562 VYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQT--SDVAWFTFDPNSGHR 619
V T I L +STY RV+A+ S P S+ ++L T + V F FD G+
Sbjct: 468 VC---GTSKIIQDLENSSTYAFRVRAYKGSICSPCSRELILHTPPAPVFSFLFDEKCGYN 524
Query: 620 D--------------------IILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDR 659
+ ++ + Q +S D ++G +KG H+W V+
Sbjct: 525 NEHLLLNLKRDRVESRAGFNLLLAAERIQVGYYTSLD--YIIGDTGITKGKHFWAFRVEP 582
Query: 660 Y 660
Y
Sbjct: 583 Y 583
Score = 46.6 bits (109), Expect = 9e-05
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPD 40
+E EL CP C LF P+ILPC H++C C + + + D
Sbjct: 27 IERELICPACKELFTHPLILPCQHSICHKCVKELLLTLDD 66
>gi|47174859 tripartite motif-containing 46 [Homo sapiens]
Length = 759
Score = 159 bits (402), Expect = 9e-39
Identities = 166/687 (24%), Positives = 265/687 (38%), Gaps = 143/687 (20%)
Query: 1 MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGSGLQAG 60
ME+EL CPVC ++++P++LPC+HNVC CAR +
Sbjct: 27 MEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVL------------------------- 61
Query: 61 AAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPSLK 120
G G G GGD + + + + T S
Sbjct: 62 --------------------------GQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRT 95
Query: 121 SPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRGLRGFQRNR 180
P R+ ++ + G+ RGA L CP C L RGL G RN
Sbjct: 96 LPKPDRLDRLLKSGFGTYPGRKRGA----LHPQVIMFPCPACQGDVELGERGLAGLFRNL 151
Query: 181 LLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHP 240
LE +V+RY+Q S A+ +CQLC + PP A C +C +C+ C HP
Sbjct: 152 TLERVVERYRQS------VSVGGAI-LCQLC-KPPPLEATKGCTECRATFCNECFKLFHP 203
Query: 241 SRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTARKF 300
A+H P T P G
Sbjct: 204 WGTQKAQHEPTLP----------------TLSFRPKG----------------------- 224
Query: 301 PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD 360
CP+H+ E + YC +C+ VC LC H+ H++ P+ + ++ K +L+++L +
Sbjct: 225 LMCPDHK-EEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILG 283
Query: 361 KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL 420
+ + +L+ ++ + +G + + L L ++A LL + + ++ +L
Sbjct: 284 NQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERL 343
Query: 421 KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE 480
+ QI L +GL+ Y EV+KE D F+Q + L R+ + E
Sbjct: 344 ARLSAQIQE-HRSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATE--ALQTFR 400
Query: 481 PKVSAEF-DLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNSVTLAWRMPPF 539
P S+ F LD ++ + +L+F+ RVP P++ ++ + + L WR+PP
Sbjct: 401 PAASSSFRHCQLDVGREMKLLTELNFL----RVPEAPVIDTQRTFA-YDQIFLCWRLPPH 455
Query: 540 T----HSPVDGYILELDDGAG---GQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSG 592
+ H V+ ++ G Q RE G L ++ S Y RV+ N +G
Sbjct: 456 SPPAWHYTVEFRRTDVPAQPGPTRWQRREEVRGTSAL--LENPDTGSVYVLRVRGCNKAG 513
Query: 593 VGPYSKTVVLQT--SDVAWFTFDPNSGHR-------------------DIILSNDNQTAT 631
G YS+ V L T + V F D G ++L+ D
Sbjct: 514 YGEYSEDVHLHTPPAPVLHFFLDSRWGASRERLAISKDQRAVRSVPGLPLLLAADRLLTG 573
Query: 632 CSSYDDRVVLGTAAFSKGVHYWELHVD 658
C D VVLG A ++G YW VD
Sbjct: 574 CHLSVD-VVLGDVAVTQGRSYWACAVD 599
>gi|89886468 fibronectin type III and SPRY domain containing 1-like
isoform 1 [Homo sapiens]
Length = 498
Score = 109 bits (273), Expect = 9e-24
Identities = 112/448 (25%), Positives = 192/448 (42%), Gaps = 69/448 (15%)
Query: 348 KAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAK 407
K L + ++ +++K E + F+ L + L+ +QEN + + L + D+L L K
Sbjct: 5 KEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKES 64
Query: 408 LLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRV 467
++ + +E+ K + + QI+ C L S L+E+ + +P F + + + RV
Sbjct: 65 MINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRV 124
Query: 468 QVSQEQWVKGALEPKVSAEF-DLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTR 526
++ + +L+PKVS L +D Q + L F+ VP P + +C
Sbjct: 125 TMASA--FRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLP----VPKAPEIDPVECLVA 178
Query: 527 NNSVTLAWRMPPFTHSPVDGYILE--------LDDGAGGQFREVYVG-KETLCTIDGLHF 577
+NSVT+AWRMP + +D +ILE L + E+ K T T+ GL F
Sbjct: 179 DNSVTVAWRMPE-EDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKF 237
Query: 578 NSTY-NARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIIL------------- 623
+S Y N RV+A N + G YS V L+T + F D +S H ++ +
Sbjct: 238 DSKYMNFRVRACNKAVAGEYSDPVTLETKALN-FNLDNSSSHLNLKVEDTCVEWDPTGGK 296
Query: 624 ---------SNDNQTATCS--------------------SYDDRVVLGTAAFSKGVHYWE 654
N ++ T S + + VLG A G HYWE
Sbjct: 297 GQESKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWE 356
Query: 655 LHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMH--CNSHTNRTEG- 711
+ + + + GVA ++ K LGK + +W ++V+N W + H N+ +
Sbjct: 357 VKAQK--DCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNN---WLQNTFAAKHNNKVKAL 411
Query: 712 GVCKGATVGVLLDLNKHTLTFFINGQQQ 739
V +GV D + L+F+ +Q
Sbjct: 412 DVTVPEKIGVFCDFDGGQLSFYDANSKQ 439
>gi|223718222 fibronectin type III and SPRY domain containing 1-like
isoform 3 [Homo sapiens]
Length = 530
Score = 108 bits (270), Expect = 2e-23
Identities = 111/445 (24%), Positives = 191/445 (42%), Gaps = 69/445 (15%)
Query: 351 LSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLT 410
L + ++ +++K E + F+ L + L+ +QEN + + L + D+L L K ++
Sbjct: 40 LQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDEVKESMIN 99
Query: 411 KVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVS 470
+ +E+ K + + QI+ C L S L+E+ + +P F + + + RV ++
Sbjct: 100 CIKQEQARKSQELQSQISQCNNALENSEELLEFATRSLDIKEPEEFSKAARQIKDRVTMA 159
Query: 471 QEQWVKGALEPKVSAEF-DLTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKCCTRNNS 529
+ +L+PKVS L +D Q + L F+ VP P + +C +NS
Sbjct: 160 SA--FRLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLP----VPKAPEIDPVECLVADNS 213
Query: 530 VTLAWRMPPFTHSPVDGYILE--------LDDGAGGQFREVYVG-KETLCTIDGLHFNST 580
VT+AWRMP + +D +ILE L + E+ K T T+ GL F+S
Sbjct: 214 VTVAWRMPE-EDNKIDHFILEHRKTNFDGLPRVKDERCWEIIDNIKGTEYTLSGLKFDSK 272
Query: 581 Y-NARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIIL---------------- 623
Y N RV+A N + G YS V L+T + F D +S H ++ +
Sbjct: 273 YMNFRVRACNKAVAGEYSDPVTLETKALN-FNLDNSSSHLNLKVEDTCVEWDPTGGKGQE 331
Query: 624 ------SNDNQTATCS--------------------SYDDRVVLGTAAFSKGVHYWELHV 657
N ++ T S + + VLG A G HYWE+
Sbjct: 332 SKIKGKENKGRSGTPSPKRTSVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKA 391
Query: 658 DRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMH--CNSHTNRTEG-GVC 714
+ + + GVA ++ K LGK + +W ++V+N W + H N+ + V
Sbjct: 392 QK--DCKSYSVGVAYKTLGKFDQLGKTNTSWCIHVNN---WLQNTFAAKHNNKVKALDVT 446
Query: 715 KGATVGVLLDLNKHTLTFFINGQQQ 739
+GV D + L+F+ +Q
Sbjct: 447 VPEKIGVFCDFDGGQLSFYDANSKQ 471
>gi|13236585 fibronectin type III and SPRY domain containing 1 [Homo
sapiens]
Length = 496
Score = 97.1 bits (240), Expect = 6e-20
Identities = 121/491 (24%), Positives = 208/491 (42%), Gaps = 78/491 (15%)
Query: 345 KQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQ 404
++ + L + + ++ K +E + F+ LK +L ++ N + L A+ +L L
Sbjct: 2 EEQREALRKIIKTLAVKNEEIQSFIYSLKQMLLNVEANSAKVQEDLEAEFQSLFSLLEEL 61
Query: 405 KAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALI 464
K +L K+ ++R + + +Q+ CT L S L+E + ++ D F Q + +
Sbjct: 62 KEGMLMKIKQDRASRTYELQNQLAACTRALESSEELLETANQTLQAMDSEDFPQAAKQI- 120
Query: 465 KRVQVSQEQWVKGALEPKVSAEFD-LTLDSEPLLQAIHQLDFIQMKCRVPPVPLLQLEKC 523
+ V+ + +L+ KVS L +D Q + L F+ VP P++ L +
Sbjct: 121 -KDGVTMAPAFRLSLKAKVSDNMSHLMVDFAQERQMLQALKFLP----VPSAPVIDLAES 175
Query: 524 CTRNNSVTLAWRMPPFTHSPVDGYILE---LDDGAGGQFRE-----VYVG-KETLCTIDG 574
+N VTL WRMP S +D Y+LE + + +E V G ++T T+ G
Sbjct: 176 LVADNCVTLVWRMPD-EDSKIDHYVLEYRRTNFEGPPRLKEDQPWMVIEGIRQTEYTLTG 234
Query: 575 LHFNSTY-NARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSN-------- 625
L F+ Y N RVKA N + G +S+ V L+T F D ++ H+++ + +
Sbjct: 235 LKFDMKYMNFRVKACNKAVAGEFSEPVTLET-PAFMFRLDASTSHQNLRVDDLSVEWDAM 293
Query: 626 ------------DNQTATCS-------------------------SYDDRVVLGTAAFSK 648
D + T S + + VLG
Sbjct: 294 GGKVQDIKAREKDGKGRTASPINSPARGTPSPKRMPSGRGGRDRFTAESYTVLGDTLIDG 353
Query: 649 GVHYWELHVDRYDNHPDP---AFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSH 705
G HYWE+ RY+ PD GVA S+ + LGK +W ++V NN H
Sbjct: 354 GEHYWEV---RYE--PDSKAFGVGVAYRSLGRFEQLGKTAASWCLHV-NNWLQVSFTAKH 407
Query: 706 TNRTEG-GVCKGATVGVLLDLNKHTLTFFINGQQQGPTAF-SHVDGVFMPALSL-NRNVQ 762
N+ + +GV D ++ L+F+ +Q F + +PA ++ + Q
Sbjct: 408 ANKVKVLDAPVPDCLGVHCDFHQGLLSFYNARTKQVLHTFKTRFTQPLLPAFTVWCGSFQ 467
Query: 763 VTLHTGLEVPT 773
VT TGL+VP+
Sbjct: 468 VT--TGLQVPS 476
>gi|78482626 ring finger protein 30 isoform 2 [Homo sapiens]
Length = 358
Score = 96.7 bits (239), Expect = 8e-20
Identities = 58/211 (27%), Positives = 104/211 (49%)
Query: 295 STARKFPTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQA 354
S A + C EHE E ++YC+SC P C LC G H EV PL ++K+ K++LS
Sbjct: 118 SKAEQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKSELSDG 177
Query: 355 LNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTK 414
+ + + + Q++ + Q I++N + L + ++L L +K +LL + +
Sbjct: 178 IAMLVAGNDRVQAVITQMEEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAR 237
Query: 415 EREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQW 474
E+E KL+ V I L S+ L+E ++ ++E + +LQ + LI +V +
Sbjct: 238 EQEEKLQRVRGLIRQYGDHLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVE 297
Query: 475 VKGALEPKVSAEFDLTLDSEPLLQAIHQLDF 505
+ G EP + T+ E + + + +DF
Sbjct: 298 LAGRPEPGYESMEQFTVRVEHVAEMLRTIDF 328
Score = 48.9 bits (115), Expect = 2e-05
Identities = 31/110 (28%), Positives = 45/110 (40%), Gaps = 12/110 (10%)
Query: 148 SSLSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAI 207
S+ SS CP C LD G+ G QRN L+E I+ Y+Q + A +
Sbjct: 67 STTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHL-- 124
Query: 208 CQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPP 257
+C+ E C C+V CS C++ F H+ + P P
Sbjct: 125 --MCEEHEEEKINIYCLSCEVPTCSLCKV--------FGAHKDCEVAPLP 164
Score = 44.7 bits (104), Expect = 3e-04
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 9/56 (16%)
Query: 1 MEEELKCPVCGSLFREPI-ILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGS 55
+E++L CP+C +F +P+ ILPC HN+C CA + PL SRGS
Sbjct: 20 LEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVF--------QASNPLWQSRGS 67
>gi|19924163 muscle specific ring finger protein 1 [Homo sapiens]
Length = 353
Score = 93.6 bits (231), Expect = 6e-19
Identities = 57/205 (27%), Positives = 101/205 (49%)
Query: 301 PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD 360
P C EHE E ++YC++C P C +C G H EV PL ++++ K +L+ ++ +
Sbjct: 120 PMCKEHEDEKINIYCLTCEVPTCSMCKVFGIHKACEVAPLQSVFQGQKTELNNCISMLVA 179
Query: 361 KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL 420
+ + QL++ + +EN + L + D L L +K++LL ++T+E+E KL
Sbjct: 180 GNDRVQTIITQLEDSRRVTKENSHQVKEELSQKFDTLYAILDEKKSELLQRITQEQEKKL 239
Query: 421 KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE 480
+ I +L +ST L+E ++ + E + FL + LIK + + + G E
Sbjct: 240 SFIEALIQQYQEQLDKSTKLVETAIQSLDEPGGATFLLTAKQLIKSIVEASKGCQLGKTE 299
Query: 481 PKVSAEFDLTLDSEPLLQAIHQLDF 505
TLD E + A+ +DF
Sbjct: 300 QGFENMDFFTLDLEHIADALRAIDF 324
Score = 48.5 bits (114), Expect = 2e-05
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 5/89 (5%)
Query: 148 SSLSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAI 207
SS+S S CP C +D G+ G QRN L+E I+ Y+Q + P +
Sbjct: 64 SSVSMSGGRFRCPTCRHEVIMDRHGVYGLQRNLLVENIIDIYKQECSSRPLQKGSH---- 119
Query: 208 CQLCDRTPPEPAATLCEQCDVLYCSACQL 236
+C E C C+V CS C++
Sbjct: 120 -PMCKEHEDEKINIYCLTCEVPTCSMCKV 147
Score = 43.9 bits (102), Expect = 6e-04
Identities = 17/35 (48%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 1 MEEELKCPVCGSLFREPI-ILPCSHNVCLPCARTI 34
+E++L CP+C +F +P+ ILPC HN+C CA I
Sbjct: 17 LEKQLICPICLEMFTKPVVILPCQHNLCRKCANDI 51
>gi|34878844 tripartite motif-containing 55 isoform 3 [Homo sapiens]
Length = 452
Score = 77.8 bits (190), Expect = 4e-14
Identities = 50/205 (24%), Positives = 99/205 (48%)
Query: 301 PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD 360
P C EHE E ++YC++C P C LC G H +V PL ++++ K++LS + +
Sbjct: 122 PMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVG 181
Query: 361 KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL 420
+ + QL++ + I+E + L + D L L +K ++ +T+ +E KL
Sbjct: 182 SNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKL 241
Query: 421 KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE 480
+ V I + L + L+E ++ + E + + FLQ + L+K++ + + + +E
Sbjct: 242 EHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIE 301
Query: 481 PKVSAEFDLTLDSEPLLQAIHQLDF 505
T++ + I ++DF
Sbjct: 302 HGYENMNHFTVNLNREEKIIREIDF 326
Score = 44.3 bits (103), Expect = 4e-04
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 152 SSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLC 211
+S CP C LD G+ G QRN L+E I+ Y+Q ++ + +C
Sbjct: 71 ASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ------ESTRPEKKSDQPMC 124
Query: 212 DRTPPEPAATLCEQCDVLYCSACQL 236
+ E C C+V CS C++
Sbjct: 125 EEHEEERINIYCLNCEVPTCSLCKV 149
Score = 43.5 bits (101), Expect = 8e-04
Identities = 17/35 (48%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 1 MEEELKCPVCGSLFREPI-ILPCSHNVCLPCARTI 34
+E++L CP+C +F +P+ ILPC HN+C CA I
Sbjct: 20 LEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54
>gi|34878836 tripartite motif-containing 55 isoform 1 [Homo sapiens]
Length = 548
Score = 77.8 bits (190), Expect = 4e-14
Identities = 50/205 (24%), Positives = 99/205 (48%)
Query: 301 PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD 360
P C EHE E ++YC++C P C LC G H +V PL ++++ K++LS + +
Sbjct: 122 PMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVG 181
Query: 361 KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL 420
+ + QL++ + I+E + L + D L L +K ++ +T+ +E KL
Sbjct: 182 SNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKL 241
Query: 421 KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE 480
+ V I + L + L+E ++ + E + + FLQ + L+K++ + + + +E
Sbjct: 242 EHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIE 301
Query: 481 PKVSAEFDLTLDSEPLLQAIHQLDF 505
T++ + I ++DF
Sbjct: 302 HGYENMNHFTVNLNREEKIIREIDF 326
Score = 44.3 bits (103), Expect = 4e-04
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 152 SSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLC 211
+S CP C LD G+ G QRN L+E I+ Y+Q ++ + +C
Sbjct: 71 ASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ------ESTRPEKKSDQPMC 124
Query: 212 DRTPPEPAATLCEQCDVLYCSACQL 236
+ E C C+V CS C++
Sbjct: 125 EEHEEERINIYCLNCEVPTCSLCKV 149
Score = 43.5 bits (101), Expect = 8e-04
Identities = 17/35 (48%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 1 MEEELKCPVCGSLFREPI-ILPCSHNVCLPCARTI 34
+E++L CP+C +F +P+ ILPC HN+C CA I
Sbjct: 20 LEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54
>gi|34878821 tripartite motif-containing 55 isoform 2 [Homo sapiens]
Length = 540
Score = 77.8 bits (190), Expect = 4e-14
Identities = 50/205 (24%), Positives = 99/205 (48%)
Query: 301 PTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSD 360
P C EHE E ++YC++C P C LC G H +V PL ++++ K++LS + +
Sbjct: 122 PMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAILVG 181
Query: 361 KAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKL 420
+ + QL++ + I+E + L + D L L +K ++ +T+ +E KL
Sbjct: 182 SNDRVQGVISQLEDTCKTIEECCRKQKQELCEKFDYLYGILEERKNEMTQVITRTQEEKL 241
Query: 421 KMVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALE 480
+ V I + L + L+E ++ + E + + FLQ + L+K++ + + + +E
Sbjct: 242 EHVRALIKKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLKKISEASKAFQMEKIE 301
Query: 481 PKVSAEFDLTLDSEPLLQAIHQLDF 505
T++ + I ++DF
Sbjct: 302 HGYENMNHFTVNLNREEKIIREIDF 326
Score = 44.3 bits (103), Expect = 4e-04
Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 6/85 (7%)
Query: 152 SSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLC 211
+S CP C LD G+ G QRN L+E I+ Y+Q ++ + +C
Sbjct: 71 ASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQ------ESTRPEKKSDQPMC 124
Query: 212 DRTPPEPAATLCEQCDVLYCSACQL 236
+ E C C+V CS C++
Sbjct: 125 EEHEEERINIYCLNCEVPTCSLCKV 149
Score = 43.5 bits (101), Expect = 8e-04
Identities = 17/35 (48%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 1 MEEELKCPVCGSLFREPI-ILPCSHNVCLPCARTI 34
+E++L CP+C +F +P+ ILPC HN+C CA I
Sbjct: 20 LEKQLICPICLEMFTKPVVILPCQHNLCRKCASDI 54
>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
Length = 868
Score = 77.4 bits (189), Expect = 5e-14
Identities = 114/523 (21%), Positives = 181/523 (34%), Gaps = 107/523 (20%)
Query: 11 GSLFREPIILPCSHNVCLPCARTIAVQTPDG-------EQHLP---QPLLLSRGSGLQAG 60
G+ R +LPC H C PC + G + P Q ++L+ +G+ A
Sbjct: 50 GAAARRLHVLPCLHAFCRPCLEAHRLPAAGGGAAGEPLKLRCPVCDQKVVLAEAAGMDAL 109
Query: 61 AAAAASLEH--DAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDSGYGSYTPS 118
++A L + DA A + G GAGG +H + ++
Sbjct: 110 PSSAFLLSNLLDAVVATADEPPPKNGRAGAPAGAGGHSNHR------------HHAHHAH 157
Query: 119 LKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSITCPQCHRSASLDHRGLRGFQR 178
++ LP P PP S +A G A S
Sbjct: 158 PRASASAPPLPQAPQPPAPSRSAPGGPAASP----------------------------- 188
Query: 179 NRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKC 238
A++ R G C CD A++ C C C C ++
Sbjct: 189 ----SALLLRRPHG---------------CSSCDEG--NAASSRCLDCQEHLCDNC-VRA 226
Query: 239 HPSRGPFAKHRLVQPPPPPPPPAEAASGPTGTAQGAPSGGGGCKSPGGAGAGATGGSTAR 298
H R K ++ PP P G A A G G PG S
Sbjct: 227 H-QRVRLTKDHYIERGPPGP----------GAAAAAQQLGLGPPFPGPPF------SILS 269
Query: 299 KFPT----CPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQA 354
FP C H+ E +YC +C P+C C GRH H L + +A Q
Sbjct: 270 VFPERLGFCQHHDDEVLHLYCDTCSVPICREC-TMGRHGGHSFIYLQEALQDSRALTIQL 328
Query: 355 LNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTK 414
L + + + Q + + +Q++ ++ + A AL ++ +LL KV K
Sbjct: 329 LADAQQGRQAIQLSIEQAQTVAEQVEMKAKVVQSEVKAVTARHKKALEERECELLWKVEK 388
Query: 415 EREHKLKMVWDQINHCTLKLRQSTGLMEYCL----EVIKENDPSGFLQISDALIKRVQVS 470
R+ K K ++ Q+ KLRQ+ +E + +V++E L D ++ QV
Sbjct: 389 IRQVKAKSLYLQVE----KLRQNLNKLESTISAVQQVLEEGRALDILLARDRML--AQVQ 442
Query: 471 QEQWVKGALEPKVSAEFDLTLDSEPLLQAIHQLDFIQMKCRVP 513
+ + V+ L+P+ T + L AI F+ P
Sbjct: 443 ELKTVRSLLQPQEDDRVMFTPPDQALYLAIKSFGFVSSGAFAP 485
>gi|78482627 ring finger protein 30 isoform 1 [Homo sapiens]
Length = 400
Score = 77.0 bits (188), Expect = 6e-14
Identities = 61/253 (24%), Positives = 104/253 (41%), Gaps = 42/253 (16%)
Query: 295 STARKFPTCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQ---- 350
S A + C EHE E ++YC+SC P C LC G H EV PL ++K+ K Q
Sbjct: 118 SKAEQHLMCEEHEEEKINIYCLSCEVPTCSLCKVFGAHKDCEVAPLPTIYKRQKKQDLTL 177
Query: 351 ---------------------------LSQALNGVSDKAKEAKEFLV-----------QL 372
SQ + + + LV Q+
Sbjct: 178 LPRLECSGTNTTYCSLDLPSSSDPPILASQNTKIIDSELSDGIAMLVAGNDRVQAVITQM 237
Query: 373 KNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTL 432
+ + Q I++N + L + ++L L +K +LL + +E+E KL+ V I
Sbjct: 238 EEVCQTIEDNSRRQKQLLNQRFESLCAVLEERKGELLQALAREQEEKLQRVRGLIRQYGD 297
Query: 433 KLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEFDLTLD 492
L S+ L+E ++ ++E + +LQ + LI +V + + G EP + T+
Sbjct: 298 HLEASSKLVESAIQSMEEPQMALYLQQAKELINKVGAMSKVELAGRPEPGYESMEQFTVR 357
Query: 493 SEPLLQAIHQLDF 505
E + + + +DF
Sbjct: 358 VEHVAEMLRTIDF 370
Score = 48.9 bits (115), Expect = 2e-05
Identities = 31/110 (28%), Positives = 45/110 (40%), Gaps = 12/110 (10%)
Query: 148 SSLSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAI 207
S+ SS CP C LD G+ G QRN L+E I+ Y+Q + A +
Sbjct: 67 STTVSSGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESSRPLHSKAEQHL-- 124
Query: 208 CQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPP 257
+C+ E C C+V CS C++ F H+ + P P
Sbjct: 125 --MCEEHEEEKINIYCLSCEVPTCSLCKV--------FGAHKDCEVAPLP 164
Score = 44.7 bits (104), Expect = 3e-04
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 9/56 (16%)
Query: 1 MEEELKCPVCGSLFREPI-ILPCSHNVCLPCARTIAVQTPDGEQHLPQPLLLSRGS 55
+E++L CP+C +F +P+ ILPC HN+C CA + PL SRGS
Sbjct: 20 LEKQLICPICLEMFSKPVVILPCQHNLCRKCANDVF--------QASNPLWQSRGS 67
>gi|55741632 fibronectin type III and SPRY domain containing 2 [Homo
sapiens]
Length = 749
Score = 75.9 bits (185), Expect = 1e-13
Identities = 73/309 (23%), Positives = 136/309 (44%), Gaps = 18/309 (5%)
Query: 305 EHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKE 364
E E E ++CV+C+TP+ H +HEV PL + K ++ + + + + E
Sbjct: 170 EDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIE 229
Query: 365 AKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVW 424
+ F L+ + ++EN E + + +++ L ++ + + + ++++ KL+ ++
Sbjct: 230 MENFANHLEEVFITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALY 289
Query: 425 DQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVS 484
Q+ C L LME E+ E I DA+ ++ + K +E
Sbjct: 290 GQLVSCGENLDTCKELMETIEEMCHEEKVD---FIKDAVAMADRLGKFLKTKTDVEISAQ 346
Query: 485 AEF-DLTLDSEPLLQAIHQLDFIQMKCRVPPVPLL--QLEKCCTRNNSVTLAWRMPPFTH 541
EF D TLD + Q + ++ I P P++ Q+ T +SV + W + ++
Sbjct: 347 PEFEDQTLDFSDVEQLMGSINTIP----APSAPVINPQVPNSAT-GSSVRVCWSL--YSD 399
Query: 542 SPVDGYILE---LDDGAGG--QFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPY 596
V+ Y L + D + G Q KET C++ L N+ Y V A N +G P
Sbjct: 400 DTVESYQLSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPS 459
Query: 597 SKTVVLQTS 605
S+ V T+
Sbjct: 460 SERAVYMTA 468
Score = 63.9 bits (154), Expect = 5e-10
Identities = 73/289 (25%), Positives = 118/289 (40%), Gaps = 37/289 (12%)
Query: 513 PPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVDGYILELDDGAGGQ---FREVYVGKETL 569
P P+++ ++ + +V + W +PVD Y +EL + E VG T
Sbjct: 469 PSPPIIKTKEIRSCEEAVLICWESGNL--NPVDSYTVELTQAESPEASGVTESVVGIPTC 526
Query: 570 CTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSNDNQT 629
++ L +Y V+A N G S+ + T ++F + ++ H + +S D T
Sbjct: 527 ESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVHTIG-SYFRLNKDTCHPWLTISEDGLT 585
Query: 630 ATCS---------SYDDR------VVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARAS 674
A S S D V+G +G HYWE+ V D H D GVA A
Sbjct: 586 AVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEV---DEHLDYRVGVAFAD 642
Query: 675 VVKDMMLGKDDKAWAM---YVDNNRSW-FMHCNSHTNRTEGGV---CKGATVGVLLDLNK 727
V K LG + +W M + + + F+H NRT + +G+LLD
Sbjct: 643 VRKQEDLGANCLSWCMRHTFASSRHKYEFLH-----NRTTPDIRITVPPKKIGILLDYEH 697
Query: 728 HTLTFFINGQQQGPTAFS-HVDGVFMPALSLNRNVQVTLHTGLEVPTNL 775
L+FF Q FS + P SL + + +H G+ +P ++
Sbjct: 698 SKLSFFNVDLSQHLYTFSCQLHEFVHPCFSLEKPGCLKVHNGISMPKHV 746
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 70.5 bits (171), Expect = 6e-12
Identities = 76/277 (27%), Positives = 118/277 (42%), Gaps = 28/277 (10%)
Query: 513 PPVPLLQLEKCCTRNNSVTLAWRMPPFTHSPVDGYILEL--DDGAGGQFREVYVGKETLC 570
P P+++ E C N+ T+ WR P T + Y LE G+ + G + L
Sbjct: 3804 PSTPVIRAEDCTVCWNTATIRWR--PTTPEATETYTLEYCRQHSPEGEGLRSFSGIKGLQ 3861
Query: 571 TIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSNDNQTA 630
L N Y V+A N+ G S+ ++ T F + H + +S+ +
Sbjct: 3862 LKVNLQPNDNYFFYVRAINAFGTSEQSEAALISTRGTR-FLLLRETAHPALHISS---SG 3917
Query: 631 TCSSYDDR-------VVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARASVVKDMMLGK 683
T S+ +R VLG S G HYWE V + P G+ +S V+ LG+
Sbjct: 3918 TVISFGERRRLTEIPSVLGEELPSCGQHYWETTV---TDCPAYRLGICSSSAVQAGALGQ 3974
Query: 684 DDKAWAMYV-DNNRSWFMHCN--SHTNRTEGGVCKGATVGVLLDLNKHTLTFFINGQQQG 740
+ +W M+ + R F + S + TE + A VG+LLD N L F +Q
Sbjct: 3975 GETSWYMHCSEPQRYTFFYSGIVSDVHVTE----RPARVGILLDYNNQRLIFINAESEQL 4030
Query: 741 PTAFSH--VDGVFMPALSLNRNVQVTLHTGLEVPTNL 775
H +GV PA +L + + TLH G+E P ++
Sbjct: 4031 LFIIRHRFNEGVH-PAFALEKPGKCTLHLGIEPPDSV 4066
Score = 61.6 bits (148), Expect = 3e-09
Identities = 63/300 (21%), Positives = 123/300 (41%), Gaps = 16/300 (5%)
Query: 314 YCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDKAKEAKEFLVQLK 373
YC +C+ P+ G H HEV L K QL++ L + +K+ + F+ +++
Sbjct: 3512 YCYTCKCPISATDKVFGTHKDHEVSTLDTAISAVKVQLAEFLENLQEKSLRIEAFVSEIE 3571
Query: 374 NILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLK 433
+ I+EN E L Q + ++ + Q + + ++ K++ + +Q+ H
Sbjct: 3572 SFFNTIEENCSKNEKRLEEQNEEMMKKVLAQYDEKAQSFEEVKKKKMEFLHEQMVHFLQS 3631
Query: 434 LRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEPKVSAEFDLTLDS 493
+ + +E + +E D + FL + + +R+ + E P + F+ DS
Sbjct: 3632 MDTAKDTLETIVREAEELDEAVFLTSFEEINERLLSAMESTASLEKMPAAFSLFEHYDDS 3691
Query: 494 EPLLQAIHQLDFIQMKCRVPPVPLLQ-LEKCCTRNNSVTLAWRMPPFTHSPVDG---YIL 549
+ D + + VP P L+ E + ++ + W M +D Y +
Sbjct: 3692 SA------RSDQMLKQVAVPQPPRLEPQEPNSATSTTIAVYWSMN--KEDVIDSFQVYCM 3743
Query: 550 E--LDDGAGGQFREVY--VGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTS 605
E DD + E Y KE+ C + L + Y V A N +G S+ + +T+
Sbjct: 3744 EEPQDDQEVNELVEEYRLTVKESYCIFEDLEPDRCYQVWVMAVNFTGCSLPSERAIFRTA 3803
>gi|194248081 tripartite motif-containing 2 isoform 2 [Homo sapiens]
Length = 744
Score = 68.9 bits (167), Expect = 2e-11
Identities = 48/205 (23%), Positives = 88/205 (42%), Gaps = 3/205 (1%)
Query: 302 TCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDK 361
+CP H+ YC SC T +C C E G HA+H PL + +QHKA L L+ V+ +
Sbjct: 117 SCPNHDGNVMEFYCQSCETAMCRECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAVNKR 175
Query: 362 AKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLK 421
E L + I+ Q+ + + D L L +K+ LL ++ K K
Sbjct: 176 LPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHK 235
Query: 422 MVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEP 481
++ Q++ + + + + L + + +++ +Q L P
Sbjct: 236 VLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQ--DFPLHP 293
Query: 482 KVSAEFDLTLDSEPLLQAIHQLDFI 506
+ + + D +++E L ++IH L I
Sbjct: 294 RENDQLDFIVETEGLKKSIHNLGTI 318
Score = 32.7 bits (73), Expect = 1.3
Identities = 22/108 (20%), Positives = 42/108 (38%), Gaps = 12/108 (11%)
Query: 150 LSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRG------AVPGTSAAA 203
+ + S +++CP C +++ L +G+ Q N + ++ Q+ G ++ T A
Sbjct: 51 IPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAV 110
Query: 204 AVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLV 251
A C C+ C+ C C + G A+H V
Sbjct: 111 AAGKPLSCPNHDGNVMEFYCQSCETAMCREC------TEGEHAEHPTV 152
>gi|194248079 tripartite motif-containing 2 isoform 1 [Homo sapiens]
Length = 771
Score = 68.9 bits (167), Expect = 2e-11
Identities = 48/205 (23%), Positives = 88/205 (42%), Gaps = 3/205 (1%)
Query: 302 TCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDK 361
+CP H+ YC SC T +C C E G HA+H PL + +QHKA L L+ V+ +
Sbjct: 144 SCPNHDGNVMEFYCQSCETAMCRECTE-GEHAEHPTVPLKDVVEQHKASLQVQLDAVNKR 202
Query: 362 AKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLK 421
E L + I+ Q+ + + D L L +K+ LL ++ K K
Sbjct: 203 LPEIDSALQFISEIIHQLTNQKASIVDDIHSTFDELQKTLNVRKSVLLMELEVNYGLKHK 262
Query: 422 MVWDQINHCTLKLRQSTGLMEYCLEVIKENDPSGFLQISDALIKRVQVSQEQWVKGALEP 481
++ Q++ + + + + L + + +++ +Q L P
Sbjct: 263 VLQSQLDTLLQGQESIKSCSNFTAQALNHGTETEVLLVKKQMSEKLNELADQ--DFPLHP 320
Query: 482 KVSAEFDLTLDSEPLLQAIHQLDFI 506
+ + + D +++E L ++IH L I
Sbjct: 321 RENDQLDFIVETEGLKKSIHNLGTI 345
Score = 32.7 bits (73), Expect = 1.3
Identities = 22/108 (20%), Positives = 42/108 (38%), Gaps = 12/108 (11%)
Query: 150 LSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRG------AVPGTSAAA 203
+ + S +++CP C +++ L +G+ Q N + ++ Q+ G ++ T A
Sbjct: 78 IPAHSLTLSCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRTPGSNAEESSILETVTAV 137
Query: 204 AVAICQLCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLV 251
A C C+ C+ C C + G A+H V
Sbjct: 138 AAGKPLSCPNHDGNVMEFYCQSCETAMCREC------TEGEHAEHPTV 179
>gi|32454739 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 58.9 bits (141), Expect = 2e-08
Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Query: 302 TCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDK 361
+CP HE + YC +C T +C C G H +H L + +QHKA L + L V +
Sbjct: 114 SCPNHEGKTMEFYCEACETAMCGEC-RAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGR 172
Query: 362 AKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLK 421
+ + + I QQ+QE + A + A + L AL ++K L++ + K K
Sbjct: 173 LPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQK 232
Query: 422 MVWDQIN 428
++ Q++
Sbjct: 233 VLQSQLD 239
Score = 36.2 bits (82), Expect = 0.12
Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 4/98 (4%)
Query: 150 LSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQ 209
+ + S +++CP C +++ L +G+ Q N + ++++ QQ +++
Sbjct: 50 IPAQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVA 109
Query: 210 ----LCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRG 243
C + CE C+ C C+ H G
Sbjct: 110 GRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHG 147
>gi|32454737 tripartite motif-containing 3 [Homo sapiens]
Length = 744
Score = 58.9 bits (141), Expect = 2e-08
Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 1/127 (0%)
Query: 302 TCPEHEMENYSMYCVSCRTPVCYLCLEEGRHAKHEVKPLGAMWKQHKAQLSQALNGVSDK 361
+CP HE + YC +C T +C C G H +H L + +QHKA L + L V +
Sbjct: 114 SCPNHEGKTMEFYCEACETAMCGEC-RAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGR 172
Query: 362 AKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLK 421
+ + + I QQ+QE + A + A + L AL ++K L++ + K K
Sbjct: 173 LPQLSAAIALVGGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQK 232
Query: 422 MVWDQIN 428
++ Q++
Sbjct: 233 VLQSQLD 239
Score = 36.2 bits (82), Expect = 0.12
Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 4/98 (4%)
Query: 150 LSSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQ 209
+ + S +++CP C +++ L +G+ Q N + ++++ QQ +++
Sbjct: 50 IPAQSLTLSCPVCRQTSILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVA 109
Query: 210 ----LCDRTPPEPAATLCEQCDVLYCSACQLKCHPSRG 243
C + CE C+ C C+ H G
Sbjct: 110 GRPLSCPNHEGKTMEFYCEACETAMCGECRAGEHREHG 147
>gi|122937424 one cut homeobox 3 [Homo sapiens]
Length = 494
Score = 57.0 bits (136), Expect = 7e-08
Identities = 76/286 (26%), Positives = 98/286 (34%), Gaps = 62/286 (21%)
Query: 54 GSGLQAGAAAAASLEHDAAAGPAC--------------GGAGGSAAGGLGGG--AGGGGD 97
G L G A +A+ +H P GG GG AGG GG AGGG D
Sbjct: 20 GELLSPGHARSAAAQHRGLVAPGRPGLVAGMASLLDGGGGGGGGGAGGAGGAGSAGGGAD 79
Query: 98 HADKLSLYSETDSGYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSSI 157
+L+ G P L + P+ PP ++ A ++ + + +
Sbjct: 80 FRGELAGPLHPAMGMACEAPGLGGTY-TTLTPLQHLPPLAAVADKFHQHAAAAAVAGAHG 138
Query: 158 TCPQCHRSASLDHRGLRGFQRNRLLEAIVQRYQQGRGAVPGTSAAAAVAICQLCDRTPPE 217
P H + QR L A V G + AA ++ L E
Sbjct: 139 GHPHAHPHPAAAPPPPPPPQR---LAASVS----GSFTLMRDERAALASVGHLYGPYGKE 191
Query: 218 PAATLCEQCDVLYCSACQLKCHPSRGPFAKHRLVQPPPPPPPPAEAASGPTG-------- 269
L L P+ P A H QPPPPPPPP AA GP G
Sbjct: 192 -----------LPAMGSPLSPLPNALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLL 240
Query: 270 ------------------TAQGAPSGGGGCKSPGGAGAGATGGSTA 297
A+G P GGGG S GGAG+G+ G A
Sbjct: 241 PPAAFEPHAALLGRAEDALARGLPGGGGGTGS-GGAGSGSAAGLLA 285
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 56.6 bits (135), Expect = 9e-08
Identities = 35/106 (33%), Positives = 53/106 (50%)
Query: 51 LSRGSGLQAGAAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDS 110
L R + + AAAAA++ G G GG + G GGG GGGG ++ + +
Sbjct: 54 LFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASN 113
Query: 111 GYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSS 156
G G + + GV + A GSS++++ ++ SS SSSSSS
Sbjct: 114 GSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSS 159
Score = 34.3 bits (77), Expect = 0.46
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 5/61 (8%)
Query: 240 PSRGPFAKH--RLVQPPPPPPPPAEAASGPT---GTAQGAPSGGGGCKSPGGAGAGATGG 294
PS GP A L +P P A AA+ + G G GGGG GG G G GG
Sbjct: 42 PSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGG 101
Query: 295 S 295
S
Sbjct: 102 S 102
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 56.6 bits (135), Expect = 9e-08
Identities = 35/106 (33%), Positives = 53/106 (50%)
Query: 51 LSRGSGLQAGAAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDS 110
L R + + AAAAA++ G G GG + G GGG GGGG ++ + +
Sbjct: 54 LFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASN 113
Query: 111 GYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSS 156
G G + + GV + A GSS++++ ++ SS SSSSSS
Sbjct: 114 GSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSS 159
Score = 34.3 bits (77), Expect = 0.46
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 5/61 (8%)
Query: 240 PSRGPFAKH--RLVQPPPPPPPPAEAASGPT---GTAQGAPSGGGGCKSPGGAGAGATGG 294
PS GP A L +P P A AA+ + G G GGGG GG G G GG
Sbjct: 42 PSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGG 101
Query: 295 S 295
S
Sbjct: 102 S 102
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 56.6 bits (135), Expect = 9e-08
Identities = 35/106 (33%), Positives = 53/106 (50%)
Query: 51 LSRGSGLQAGAAAAASLEHDAAAGPACGGAGGSAAGGLGGGAGGGGDHADKLSLYSETDS 110
L R + + AAAAA++ G G GG + G GGG GGGG ++ + +
Sbjct: 54 LFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASN 113
Query: 111 GYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLSSSSSS 156
G G + + GV + A GSS++++ ++ SS SSSSSS
Sbjct: 114 GSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSSSSSSSSS 159
Score = 34.3 bits (77), Expect = 0.46
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 5/61 (8%)
Query: 240 PSRGPFAKH--RLVQPPPPPPPPAEAASGPT---GTAQGAPSGGGGCKSPGGAGAGATGG 294
PS GP A L +P P A AA+ + G G GGGG GG G G GG
Sbjct: 42 PSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGG 101
Query: 295 S 295
S
Sbjct: 102 S 102
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,314,800
Number of Sequences: 37866
Number of extensions: 2051636
Number of successful extensions: 38336
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 652
Number of HSP's successfully gapped in prelim test: 726
Number of HSP's that attempted gapping in prelim test: 22331
Number of HSP's gapped (non-prelim): 11793
length of query: 783
length of database: 18,247,518
effective HSP length: 110
effective length of query: 673
effective length of database: 14,082,258
effective search space: 9477359634
effective search space used: 9477359634
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.