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Search of human proteins with 134142348
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134142348 myotubularin related protein 6 [Homo sapiens]
(621 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134142348 myotubularin related protein 6 [Homo sapiens] 1271 0.0
gi|225543474 myotubularin related protein 7 [Homo sapiens] 734 0.0
gi|21361759 myotubularin related protein 8 [Homo sapiens] 714 0.0
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 371 e-102
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 371 e-102
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 371 e-102
gi|4557896 myotubularin [Homo sapiens] 360 3e-99
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 347 1e-95
gi|19923424 myotubularin related protein 9 [Homo sapiens] 324 1e-88
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 280 4e-75
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 280 4e-75
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 280 4e-75
gi|217272865 myotubularin related protein 4 [Homo sapiens] 269 6e-72
gi|124028527 myotubularin related protein 10 [Homo sapiens] 130 3e-30
gi|239735519 SET binding factor 1 [Homo sapiens] 126 7e-29
gi|29788755 SET binding factor 2 [Homo sapiens] 118 1e-26
gi|94721263 myotubularin related protein 12 [Homo sapiens] 118 2e-26
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 99 9e-21
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 99 9e-21
gi|117938274 jumpy isoform 3 [Homo sapiens] 37 0.054
gi|117938272 jumpy isoform 1 [Homo sapiens] 37 0.054
gi|117938270 jumpy isoform 2 [Homo sapiens] 37 0.054
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 35 0.21
gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-l... 34 0.35
gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-l... 34 0.35
gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-l... 34 0.35
gi|169208016 PREDICTED: similar to golgi autoantigen, golgin sub... 34 0.35
gi|24497453 nucleoporin 88kDa [Homo sapiens] 34 0.46
gi|125490354 spermatogenesis associated 1 [Homo sapiens] 34 0.46
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 33 0.78
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 1271 bits (3290), Expect = 0.0
Identities = 621/621 (100%), Positives = 621/621 (100%)
Query: 1 MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSHQKETWILHHHIASVEKLA 60
MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSHQKETWILHHHIASVEKLA
Sbjct: 1 MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSHQKETWILHHHIASVEKLA 60
Query: 61 LTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDSE 120
LTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDSE
Sbjct: 61 LTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDSE 120
Query: 121 RLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKF 180
RLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKF
Sbjct: 121 RLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKF 180
Query: 181 RSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVMDTR 240
RSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVMDTR
Sbjct: 181 RSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVMDTR 240
Query: 241 PKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYS 300
PKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYS
Sbjct: 241 PKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYS 300
Query: 301 GLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRT 360
GLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRT
Sbjct: 301 GLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRT 360
Query: 361 IKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEA 420
IKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEA
Sbjct: 361 IKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEA 420
Query: 421 FLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRF 480
FLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRF
Sbjct: 421 FLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRF 480
Query: 481 TVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQR 540
TVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQR
Sbjct: 481 TVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQR 540
Query: 541 KNKQTDGILTKELLHSVHPESPNLKTSLCFKEQTLLPVNDALRTIEGSSPADNRYSEYAE 600
KNKQTDGILTKELLHSVHPESPNLKTSLCFKEQTLLPVNDALRTIEGSSPADNRYSEYAE
Sbjct: 541 KNKQTDGILTKELLHSVHPESPNLKTSLCFKEQTLLPVNDALRTIEGSSPADNRYSEYAE 600
Query: 601 EFSKSEPAVVSLEYGVARMTC 621
EFSKSEPAVVSLEYGVARMTC
Sbjct: 601 EFSKSEPAVVSLEYGVARMTC 621
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 734 bits (1896), Expect = 0.0
Identities = 349/550 (63%), Positives = 447/550 (81%), Gaps = 7/550 (1%)
Query: 1 MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSH---QKETWILHHHIASVE 57
MEHIRT KVE V+L+DR S +L GTLYLTATH++F+++ +KETWILH I+++E
Sbjct: 1 MEHIRTPKVENVRLVDRVSPKKAAL-GTLYLTATHVIFVENSPDPRKETWILHSQISTIE 59
Query: 58 KLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQN 117
K A T +GCPL+I+CKNF+ + I+P+ERDCHD+Y SL++L++ KYE+LY FS+NP +
Sbjct: 60 KQATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYEELYCFSFNPMLD 119
Query: 118 DSERLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGS 177
ER QGW LIDL+EEY RMG+PN +WQLSD NRDY++C++YP ELYVP+ A+ IIVGS
Sbjct: 120 KEEREQGWVLIDLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGS 179
Query: 178 SKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVM 237
SKFRS+ RFPVLSYY++D A+ICR SQPLSGFSARCLEDE +LQAI KANP + ++YV+
Sbjct: 180 SKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVV 239
Query: 238 DTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVND 297
DTRPKLNAMANRAAGKGYENEDNYSNI+FQF+GIENIHVMR+SLQK+LEV K S++D
Sbjct: 240 DTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSD 299
Query: 298 FYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSY 357
F GLE+SGWLRHIKA+MDA IF+AKA++ E ASVLVHCSDGWDRT+QVCS+ SLLLD +
Sbjct: 300 FLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPH 359
Query: 358 YRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEF 417
YRT+KGFMVLIEKDWISFGHKF+ R G LDGDPKE+SPV QF+ECVW L EQFP AFEF
Sbjct: 360 YRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEF 419
Query: 418 SEAFLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSES 477
+E FL+ I HI+SCQFGNFL N QKER ELK++E+TYSLW L +++ YLNPL+ ++
Sbjct: 420 NERFLIHIQHHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADH 479
Query: 478 HRF--TVLEPNT-VSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLE 534
+ T+ P T +F +KFW MY++F++ + PRQSV + +M + E+ +QLE++++ LE
Sbjct: 480 SQTQGTLHLPTTPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALE 539
Query: 535 SKIKQRKNKQ 544
++++ + Q
Sbjct: 540 ERLEKIQKVQ 549
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 714 bits (1844), Expect = 0.0
Identities = 334/543 (61%), Positives = 431/543 (79%), Gaps = 5/543 (0%)
Query: 1 MEHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFIDSH---QKETWILHHHIASVE 57
M+HI KVE VKL+DR+ S K G LYLTATHL+++++ +KETWI HHIA+VE
Sbjct: 1 MDHITVPKVENVKLVDRY-VSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVE 59
Query: 58 KLALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQN 117
KL +T+ GCPL ++CKNFR HF++ + CH++Y SLL+LS+ A EDLYAFSYNPK +
Sbjct: 60 KLPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSS 119
Query: 118 DSERLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGS 177
R GW+LID ++ RMG+PN +W ++DANR+Y+IC TYP E+ VP+ + +VGS
Sbjct: 120 KEMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGS 179
Query: 178 SKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVM 237
SKFRSK R PVLSY +++ AAICRCSQPLSGF RC++DE LL+AIS+ NP +++MYV+
Sbjct: 180 SKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVV 239
Query: 238 DTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVND 297
DTRPKLNAMANRAAGKGYENEDNY+NIRF+F+GIENIHVMRSSLQKLLEV K ++++
Sbjct: 240 DTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSE 299
Query: 298 FYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSY 357
F SGLESSGWLRHIKA+MDA IF+ KA+ VE ASVLVHCSDGWDRT+QVCS+ S+LLD +
Sbjct: 300 FLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPF 359
Query: 358 YRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEF 417
YRT KG M+LIEK+WIS GHKFS+RCG LDGD KEVSP+FTQFL+C+W L EQFP AFEF
Sbjct: 360 YRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEF 419
Query: 418 SEAFLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSES 477
+E FLL+IH+H+ SCQFGNFLGNCQK+RE+L++ EKT+S+WPFL++ + + NPLY +
Sbjct: 420 NENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFT 479
Query: 478 HRFTVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKI 537
+ VL P+TV +N +FW MY++FD+ L P+QS+ ++ + +Q LE D+ +LE K+
Sbjct: 480 -MYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKL 538
Query: 538 KQR 540
K R
Sbjct: 539 KVR 541
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 371 bits (952), Expect = e-102
Identities = 203/535 (37%), Positives = 308/535 (57%), Gaps = 19/535 (3%)
Query: 24 SLTGTLYLTATHLLFIDSHQKETWILHHHIA---SVEKLALTTS----GCPLVIQCKNFR 76
++ GTL +T L F + ++L + VEK+ +S L CK+ R
Sbjct: 100 AVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIR 159
Query: 77 TVHFI-VPRERDCHDIYNSLLQLSKQAKYE-DLYAFSYNPKQNDSERLQGWQLIDLAEEY 134
+ F P R I+ +L++ + L+AF Y ++ GW+L D EY
Sbjct: 160 NLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----GWKLYDPLLEY 215
Query: 135 KRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQ 194
+R G+PN W+++ N Y++C+TYP L VP + + FRS+GR PVLS+ H
Sbjct: 216 RRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHP 275
Query: 195 DKEAAICRCSQPLSGFSA-RCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGK 253
+ +A I RCSQP+ G S R EDE LQAI +N + +++ D RP +NA+AN+A G
Sbjct: 276 ESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGG 335
Query: 254 GYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKA 313
GYE+ED Y N F+ I NIHVMR SL+KL E+ + + S LES+ WL HIK
Sbjct: 336 GYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV-YPNIEETHWLSNLESTHWLEHIKL 394
Query: 314 VMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWI 373
++ A+ +A + SV+VHCSDGWDRT+Q+ SL L+LD YYRTI+GF VL+EK+W+
Sbjct: 395 ILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWL 454
Query: 374 SFGHKFSERCGQLDGDPKEV--SPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHS 431
SFGH+F R G D + + SPVF QF++CVW +T QFP AFEF+E FL+ I +H++S
Sbjct: 455 SFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYS 514
Query: 432 CQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFN 491
C FG FL N +++R + L ++T SLW ++ + + NPLY S S+ VL P +
Sbjct: 515 CLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH--VLYPVASMRH 572
Query: 492 FKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQTD 546
+ W Y +++ + P++ + N + + +L+K +++L+ +I R ++
Sbjct: 573 LELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSE 627
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 371 bits (952), Expect = e-102
Identities = 203/535 (37%), Positives = 308/535 (57%), Gaps = 19/535 (3%)
Query: 24 SLTGTLYLTATHLLFIDSHQKETWILHHHIA---SVEKLALTTS----GCPLVIQCKNFR 76
++ GTL +T L F + ++L + VEK+ +S L CK+ R
Sbjct: 28 AVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIR 87
Query: 77 TVHFI-VPRERDCHDIYNSLLQLSKQAKYE-DLYAFSYNPKQNDSERLQGWQLIDLAEEY 134
+ F P R I+ +L++ + L+AF Y ++ GW+L D EY
Sbjct: 88 NLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----GWKLYDPLLEY 143
Query: 135 KRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQ 194
+R G+PN W+++ N Y++C+TYP L VP + + FRS+GR PVLS+ H
Sbjct: 144 RRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHP 203
Query: 195 DKEAAICRCSQPLSGFSA-RCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGK 253
+ +A I RCSQP+ G S R EDE LQAI +N + +++ D RP +NA+AN+A G
Sbjct: 204 ESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGG 263
Query: 254 GYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKA 313
GYE+ED Y N F+ I NIHVMR SL+KL E+ + + S LES+ WL HIK
Sbjct: 264 GYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV-YPNIEETHWLSNLESTHWLEHIKL 322
Query: 314 VMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWI 373
++ A+ +A + SV+VHCSDGWDRT+Q+ SL L+LD YYRTI+GF VL+EK+W+
Sbjct: 323 ILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWL 382
Query: 374 SFGHKFSERCGQLDGDPKEV--SPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHS 431
SFGH+F R G D + + SPVF QF++CVW +T QFP AFEF+E FL+ I +H++S
Sbjct: 383 SFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYS 442
Query: 432 CQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFN 491
C FG FL N +++R + L ++T SLW ++ + + NPLY S S+ VL P +
Sbjct: 443 CLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH--VLYPVASMRH 500
Query: 492 FKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQTD 546
+ W Y +++ + P++ + N + + +L+K +++L+ +I R ++
Sbjct: 501 LELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSE 555
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 371 bits (952), Expect = e-102
Identities = 203/535 (37%), Positives = 308/535 (57%), Gaps = 19/535 (3%)
Query: 24 SLTGTLYLTATHLLFIDSHQKETWILHHHIA---SVEKLALTTS----GCPLVIQCKNFR 76
++ GTL +T L F + ++L + VEK+ +S L CK+ R
Sbjct: 28 AVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIR 87
Query: 77 TVHFI-VPRERDCHDIYNSLLQLSKQAKYE-DLYAFSYNPKQNDSERLQGWQLIDLAEEY 134
+ F P R I+ +L++ + L+AF Y ++ GW+L D EY
Sbjct: 88 NLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----GWKLYDPLLEY 143
Query: 135 KRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQ 194
+R G+PN W+++ N Y++C+TYP L VP + + FRS+GR PVLS+ H
Sbjct: 144 RRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHP 203
Query: 195 DKEAAICRCSQPLSGFSA-RCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGK 253
+ +A I RCSQP+ G S R EDE LQAI +N + +++ D RP +NA+AN+A G
Sbjct: 204 ESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGG 263
Query: 254 GYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKA 313
GYE+ED Y N F+ I NIHVMR SL+KL E+ + + S LES+ WL HIK
Sbjct: 264 GYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV-YPNIEETHWLSNLESTHWLEHIKL 322
Query: 314 VMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWI 373
++ A+ +A + SV+VHCSDGWDRT+Q+ SL L+LD YYRTI+GF VL+EK+W+
Sbjct: 323 ILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWL 382
Query: 374 SFGHKFSERCGQLDGDPKEV--SPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHS 431
SFGH+F R G D + + SPVF QF++CVW +T QFP AFEF+E FL+ I +H++S
Sbjct: 383 SFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYS 442
Query: 432 CQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFN 491
C FG FL N +++R + L ++T SLW ++ + + NPLY S S+ VL P +
Sbjct: 443 CLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH--VLYPVASMRH 500
Query: 492 FKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQTD 546
+ W Y +++ + P++ + N + + +L+K +++L+ +I R ++
Sbjct: 501 LELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSE 555
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 360 bits (923), Expect = 3e-99
Identities = 198/501 (39%), Positives = 298/501 (59%), Gaps = 19/501 (3%)
Query: 22 NKSLTGTLYLTATHLLFIDSHQKETWILHHH---IASVEKLALTTS----GCPLVIQCKN 74
N + G +Y+T L + IL I+ +EK+ TS L I CK+
Sbjct: 56 NGPIKGRVYITNYRLYLRSLETDSSLILDVPLGVISRIEKMGGATSRGENSYGLDITCKD 115
Query: 75 FRTVHFIVPRE-RDCHDIYNSLLQLSKQAKYE-DLYAFSYNPKQNDSERLQGWQLIDLAE 132
R + F + +E D++ L + + + L+AF K N + GW + + E
Sbjct: 116 MRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLPLFAFLNEEKFN----VDGWTVYNPVE 171
Query: 133 EYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYY 192
EY+R G+PN HW+++ N+ Y++C+TYP L VP AS + + FRS+ R PVLS+
Sbjct: 172 EYRRQGLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWI 231
Query: 193 HQDKEAAICRCSQPLSGFSA-RCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAA 251
H + + I RCSQPL G S R +DE L I + N + + D RP +NA+AN+A
Sbjct: 232 HPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARPSVNAVANKAT 291
Query: 252 GKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHI 311
G GYE++D Y N F+ I NIHVMR SL+K+ ++ + + + S LES+ WL HI
Sbjct: 292 GGGYESDDAYHNAELFFLDIHNIHVMRESLKKVKDIV-YPNVEESHWLSSLESTHWLEHI 350
Query: 312 KAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKD 371
K V+ AI +A ++ +SVLVHCSDGWDRT+Q+ SL L+LDS+YR+I+GF +L++K+
Sbjct: 351 KLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIEGFEILVQKE 410
Query: 372 WISFGHKFSERCGQLDGDPKEV--SPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHI 429
WISFGHKF+ R G D + + SP+F QF++CVW +++QFP AFEF+E FL+ I +H+
Sbjct: 411 WISFGHKFASRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQFLIIILDHL 470
Query: 430 HSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVS 489
+SC+FG FL NC+ RE K+ E+T SLW + +++K+ NP Y+ E +R VL P
Sbjct: 471 YSCRFGTFLFNCESARERQKVTERTVSLWSLINSNKEKFKNPFYTKEINR--VLYPVASM 528
Query: 490 FNFKFWRNMYHQFDRTLHPRQ 510
+ + W N Y +++ + +Q
Sbjct: 529 RHLELWVNYYIRWNPRIKQQQ 549
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 347 bits (891), Expect = 1e-95
Identities = 196/529 (37%), Positives = 302/529 (57%), Gaps = 20/529 (3%)
Query: 24 SLTGTLYLTATHLLFIDSHQKETWILHHH---IASVEKLALTTSG---CPLVIQCKNFRT 77
+++GTL +T L F + + +IL I+ VEK+ + G C + I CK+ R
Sbjct: 122 AVSGTLTVTDFKLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCGIEIVCKDMRN 181
Query: 78 VHFIVPRERDCH-DIYNSLLQLS-KQAKYEDLYAFSYNPKQNDSERLQGWQLIDLAEEYK 135
+ +E I+ +L + + + + L+AFSY K + GW++ D EYK
Sbjct: 182 LRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKFP----INGWKVYDPVSEYK 237
Query: 136 RMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQD 195
R G+PN W++S N +Y+ C+TYP + VP + + FR+KGR PVLS+ H +
Sbjct: 238 RQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKDDDLSKVAAFRAKGRVPVLSWIHPE 297
Query: 196 KEAAICRCSQPLSGFS-ARCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGKG 254
+A I RCSQPL G + RC EDE LQ I AN + + + D R A N+ G G
Sbjct: 298 SQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQSHKLIIFDARQNSVADTNKTKGGG 357
Query: 255 YENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAV 314
YE+E Y N F+ I NIHVMR SL+KL E+ + + S ++ + WL +I+ +
Sbjct: 358 YESESAYPNAELVFLEIHNIHVMRESLRKLKEIV-YPSIDEARWLSNVDGTHWLEYIRML 416
Query: 315 MDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWIS 374
+ A+ +A I SV+VHCSDGWDRT+Q+ SL L+LDSYYRTIKGF L+EK+WIS
Sbjct: 417 LAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAMLMLDSYYRTIKGFETLVEKEWIS 476
Query: 375 FGHKFSERCGQLDGDPKEV--SPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSC 432
FGH+F+ R G + + + SP+F QF++CVW +T QFP AFEF+E FL+ I +H++SC
Sbjct: 477 FGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTRQFPSAFEFNELFLITILDHLYSC 536
Query: 433 QFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLY-SSESHRFTVLEPNTVSFN 491
FG FL NC+++R + + KT SLW ++ ++ NP + + E+H VL P +
Sbjct: 537 LFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFSNPFFVNYENH---VLYPVASLSH 593
Query: 492 FKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQR 540
+ W N Y +++ + P+ + + + +L+K ++ L+ ++ R
Sbjct: 594 LELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVEGLQREVATR 642
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 324 bits (831), Expect = 1e-88
Identities = 188/546 (34%), Positives = 303/546 (55%), Gaps = 20/546 (3%)
Query: 2 EHIRTTKVEQVKLLDRFSTSNKSLTGTLYLTATHLLFID--SHQKETWILHHHIASVEKL 59
E I+T +V+ V L F + + GTL LT HL+ + +E W+LH +I +++K
Sbjct: 5 ELIKTPRVDNVVLHRPFYPA---VEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDKR 61
Query: 60 ALTTSGCPLVIQCKNFRTVHFIVPRERDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQNDS 119
+ + G ++I+CK+FR + +P +C +I +S+ LS +Y F Y P
Sbjct: 62 FVGSLGT-IIIKCKDFRIIQLDIPGMEECLNIASSIEALSTLDSITLMYPFFYRPMFEVI 120
Query: 120 ERLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSK 179
E GW +E++ S W+LS N+++ +C +YP + VP+ + +
Sbjct: 121 E--DGWHSFLPEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVAT 178
Query: 180 FRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSAR-CLEDEHLLQAISKANPVNRYMYVMD 238
FR GRFPVLSYYH+ I R QPL+G + R C EDE L+ A +A + Y++D
Sbjct: 179 FRHGGRFPVLSYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAG---KRGYIID 235
Query: 239 TRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDF 298
TR A RA G G+E E +Y R IE H+++ SL KL+E + +++ +
Sbjct: 236 TRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACNDQTHNMDRW 295
Query: 299 YSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYY 358
S LE+S WL HIK ++ A A+ I E AS+L+H ++G D T QV SL ++L+
Sbjct: 296 LSKLEASNWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRS 355
Query: 359 RTIKGFMVLIEKDWISFGHKFSERCGQ---LDGDPKEVSPVFTQFLECVWHLTEQFPQAF 415
RTI+GF LIE++W+ GH F +RC Q + K +PVF FL+CVW + QFP +F
Sbjct: 356 RTIRGFEALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSF 415
Query: 416 EFSEAFLLQIHEHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLE--DQKKYLNPLY 473
EF+E FL+ + EH ++ QFG FLGN + ER +LKL++KT SLW ++ + + K+ NPL+
Sbjct: 416 EFNENFLIMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLF 475
Query: 474 SSESHRFTVLEPNTVSFNFKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDL 533
+ + V+ P+ + W ++ +++R+ + ++N+ E NK+L+ + L
Sbjct: 476 EANN---LVIWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNIL 532
Query: 534 ESKIKQ 539
++ +
Sbjct: 533 RRQLAE 538
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 280 bits (715), Expect = 4e-75
Identities = 176/493 (35%), Positives = 253/493 (51%), Gaps = 64/493 (12%)
Query: 68 LVIQCKNFRTVHFIVPRERDCHDIYNSLLQ-LSKQAKYEDLYAFSYNP---KQNDSERLQ 123
L + CK+ + + C + L + AK EDL++F+Y+ + SE+ Q
Sbjct: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
Query: 124 GWQLIDLAE--------EYKRMGVP-NSHWQLSDANRDYKICETYPRELYVPRIASKPII 174
L E E +RMG N+ W++S+ N YK+C +YP+EL VP + +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
Query: 175 VGSSKFRSKGRFPVLSYYHQDKEAAICRCSQP-LSGFSARCLEDEHLLQAISKANPVN-- 231
S FRS R P + Y HQ A I RC QP +S + R +DEHL+Q+++KA +
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
Query: 232 -------------------------------------------RYMYVMDTRPKLNAMAN 248
+ + ++D R A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
Query: 249 RAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWL 308
RA G G E + Y N F+G+ NIH +R S Q L + T+ ++ S LES+ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSL-RLLCTQMPDPGNWLSALESTKWL 385
Query: 309 RHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLI 368
H+ ++ +A+ + A+ + VLVHCSDGWDRT Q+ +L LLLD YYRTI+GF VL+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 369 EKDWISFGHKFSERC--GQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIH 426
E +W+ FGHKF++RC G+ D E PVF Q+L+CV L QFP +FEF+EAFL+++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 427 EHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPN 486
+H +SC FG FL N KER E +E+T S+W L K + N LYSS+S VL P
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSE--AVLYPV 563
Query: 487 TVSFNFKFWRNMY 499
N W +Y
Sbjct: 564 CHVRNLMLWSAVY 576
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 280 bits (715), Expect = 4e-75
Identities = 176/493 (35%), Positives = 253/493 (51%), Gaps = 64/493 (12%)
Query: 68 LVIQCKNFRTVHFIVPRERDCHDIYNSLLQ-LSKQAKYEDLYAFSYNP---KQNDSERLQ 123
L + CK+ + + C + L + AK EDL++F+Y+ + SE+ Q
Sbjct: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
Query: 124 GWQLIDLAE--------EYKRMGVP-NSHWQLSDANRDYKICETYPRELYVPRIASKPII 174
L E E +RMG N+ W++S+ N YK+C +YP+EL VP + +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
Query: 175 VGSSKFRSKGRFPVLSYYHQDKEAAICRCSQP-LSGFSARCLEDEHLLQAISKANPVN-- 231
S FRS R P + Y HQ A I RC QP +S + R +DEHL+Q+++KA +
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
Query: 232 -------------------------------------------RYMYVMDTRPKLNAMAN 248
+ + ++D R A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
Query: 249 RAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWL 308
RA G G E + Y N F+G+ NIH +R S Q L + T+ ++ S LES+ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSL-RLLCTQMPDPGNWLSALESTKWL 385
Query: 309 RHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLI 368
H+ ++ +A+ + A+ + VLVHCSDGWDRT Q+ +L LLLD YYRTI+GF VL+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 369 EKDWISFGHKFSERC--GQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIH 426
E +W+ FGHKF++RC G+ D E PVF Q+L+CV L QFP +FEF+EAFL+++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 427 EHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPN 486
+H +SC FG FL N KER E +E+T S+W L K + N LYSS+S VL P
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSE--AVLYPV 563
Query: 487 TVSFNFKFWRNMY 499
N W +Y
Sbjct: 564 CHVRNLMLWSAVY 576
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 280 bits (715), Expect = 4e-75
Identities = 176/493 (35%), Positives = 253/493 (51%), Gaps = 64/493 (12%)
Query: 68 LVIQCKNFRTVHFIVPRERDCHDIYNSLLQ-LSKQAKYEDLYAFSYNP---KQNDSERLQ 123
L + CK+ + + C + L + AK EDL++F+Y+ + SE+ Q
Sbjct: 87 LHLTCKDCKVIRCQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQ 146
Query: 124 GWQLIDLAE--------EYKRMGVP-NSHWQLSDANRDYKICETYPRELYVPRIASKPII 174
L E E +RMG N+ W++S+ N YK+C +YP+EL VP + +
Sbjct: 147 HGDLCRPGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKEL 206
Query: 175 VGSSKFRSKGRFPVLSYYHQDKEAAICRCSQP-LSGFSARCLEDEHLLQAISKANPVN-- 231
S FRS R P + Y HQ A I RC QP +S + R +DEHL+Q+++KA +
Sbjct: 207 ESVSSFRSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSR 266
Query: 232 -------------------------------------------RYMYVMDTRPKLNAMAN 248
+ + ++D R A+AN
Sbjct: 267 SSGSKLSTRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVAN 326
Query: 249 RAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWL 308
RA G G E + Y N F+G+ NIH +R S Q L + T+ ++ S LES+ WL
Sbjct: 327 RAKGGGCECPEYYPNCEVVFMGMANIHSIRRSFQSL-RLLCTQMPDPGNWLSALESTKWL 385
Query: 309 RHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLI 368
H+ ++ +A+ + A+ + VLVHCSDGWDRT Q+ +L LLLD YYRTI+GF VL+
Sbjct: 386 HHLSVLLKSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLV 445
Query: 369 EKDWISFGHKFSERC--GQLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIH 426
E +W+ FGHKF++RC G+ D E PVF Q+L+CV L QFP +FEF+EAFL+++
Sbjct: 446 EMEWLDFGHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLV 505
Query: 427 EHIHSCQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPN 486
+H +SC FG FL N KER E +E+T S+W L K + N LYSS+S VL P
Sbjct: 506 QHTYSCLFGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSE--AVLYPV 563
Query: 487 TVSFNFKFWRNMY 499
N W +Y
Sbjct: 564 CHVRNLMLWSAVY 576
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 269 bits (687), Expect = 6e-72
Identities = 169/487 (34%), Positives = 254/487 (52%), Gaps = 58/487 (11%)
Query: 68 LVIQCKNFRTVHFIVPRERDCHDIYNSLLQLS-KQAKYEDLYAFSYNP-------KQNDS 119
L I CK+ + V + C + + L + + + AK EDL+AF+Y+ + +
Sbjct: 87 LHISCKDSKVVRCHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHT 146
Query: 120 ERLQGWQLIDLAEEYK--RMGVPNSH-WQLSDANRDYKICETYPRELYVPRIASKPIIVG 176
Q + I +E + RMG + W++S N +YK+C +YP++L VP + +
Sbjct: 147 HLCQPGEHIRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELEN 206
Query: 177 SSKFRSKGRFPVLSYYHQDKEAAICRCSQP-LSGFSARCLEDEHLLQAISKANPVN---- 231
+ FRS R PV+ Y H AAI RCSQP +S + R +DE+L+ +I+KA ++
Sbjct: 207 VASFRSWKRIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTR 266
Query: 232 -------------------------------------RYMYVMDTRPKLNAMANRAAGKG 254
+ + ++D R A+ANRA G G
Sbjct: 267 ATGGSLSTGNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGG 326
Query: 255 YENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAV 314
E E+ Y N F+G+ NIH +R+S Q L V +++ S LES+ WL+H+ +
Sbjct: 327 CECEEYYPNCEVVFMGMANIHAIRNSFQYLRAVCSQMP-DPSNWLSALESTKWLQHLSVM 385
Query: 315 MDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWIS 374
+ AA+ +A + E VLVHCSDGWDRT Q+ +L +LLD YYRT++GF VL+E DW+
Sbjct: 386 LKAAVLVANTVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLD 445
Query: 375 FGHKFSERCGQLDG--DPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSC 432
FGHKF +RCG + D E PVF Q+L+ V L +QFP FEF+EAFL+++ +H +SC
Sbjct: 446 FGHKFGDRCGHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSC 505
Query: 433 QFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFNF 492
+G FL N ERE+ + ++T S+W L K + N LY+ S VL P
Sbjct: 506 LYGTFLANNPCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSD--MVLHPVCHVRAL 563
Query: 493 KFWRNMY 499
W +Y
Sbjct: 564 HLWTAVY 570
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 130 bits (328), Expect = 3e-30
Identities = 121/460 (26%), Positives = 199/460 (43%), Gaps = 82/460 (17%)
Query: 68 LVIQCKNFRTVHFIVPRE--RDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQ--NDSERLQ 123
L+I CK+FR V F + ++ S+ + L+AF Y K+ N + ++
Sbjct: 134 LIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKIN 193
Query: 124 G--------------------WQLIDLAEEY-------KRMGVPNSHWQLSDANRDYKIC 156
G Q L E Y KR G S W++ N Y I
Sbjct: 194 GIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMIS 251
Query: 157 ETYPRELYVP-RIASKPIIVGSSKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCL 215
P + VP +A + + + S F + R P+ + H + +A+ R + R +
Sbjct: 252 TCLPEYIVVPSSLADQDLKIFSHSFVGR-RMPLWCWSHSN-GSALVRMALIKDVLQQRKI 309
Query: 216 EDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIH 275
D+ + AI+K++P +Y D L N ++ FV +
Sbjct: 310 -DQRICNAITKSHPQRSDVYKSDLDKTL---------------PNIQEVQAAFVKL---- 349
Query: 276 VMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVH 335
K L VN + + S LE++ WL +++A + + L + ++ SV++
Sbjct: 350 -------KQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQ 402
Query: 336 CSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSP 395
+G D + V SL ++LD Y+RTI GF LI+K+W+ G++F +RC L KE SP
Sbjct: 403 EEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE-SP 461
Query: 396 VFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKER---------- 445
+F FL+ W L EQ+P AFEFSE +L +++ FG FL N +R
Sbjct: 462 LFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAIS 521
Query: 446 EELKLKE----KTYSLW----PFLLEDQKKYLNPLYSSES 477
+ ++L + K S+W F +D+ + NP Y +S
Sbjct: 522 KNIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKS 561
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 126 bits (316), Expect = 7e-29
Identities = 96/281 (34%), Positives = 145/281 (51%), Gaps = 26/281 (9%)
Query: 235 YVMDTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHV--MRSSLQKLLE--VNGT 290
++ R L + ++A KG ++ +++ V IE +++S +KLL+ V G
Sbjct: 1344 FLRPQRAALYILGDKAQLKGVRSDPLQ---QWELVPIEVFEARQVKASFKKLLKACVPGC 1400
Query: 291 KGL--SVNDFYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCS 348
S F LE S WL I ++ ++ + + + +SVLV DGWD T+QV S
Sbjct: 1401 PAAEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLD-SGSSVLVGLEDGWDITTQVVS 1459
Query: 349 LGSLLLDSYYRTIKGFMVLIEKDWISFGHKFSER-CGQLDGDPKEVSPVFTQFLECVWHL 407
L LL D +YRT++GF +L+EK+W+SFGH+FS R L G +PVF QFL+CV +
Sbjct: 1460 LVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQSSGFTPVFLQFLDCVHQV 1519
Query: 408 TEQFPQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKEREELKL--KEK--------TYSL 457
QFP FEFS+ +L + H S +F FL + ER EL L +EK S+
Sbjct: 1520 HLQFPMEFEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGERRGQVPCRSV 1579
Query: 458 WPFLLEDQKK---YLNPLYSSESHRFTVLEPNTVSFNFKFW 495
W ++ K+ + N +Y+ E VL P + N K W
Sbjct: 1580 WEYVDRLSKRTPVFHNYMYAPEDAE--VLRPYSNVSNLKVW 1618
Score = 37.4 bits (85), Expect = 0.041
Identities = 35/141 (24%), Positives = 60/141 (42%), Gaps = 30/141 (21%)
Query: 119 SERLQGWQLIDLA--EEYKRMGV----------PNSHWQLSDANRDYKICETYPRELYVP 166
S+R+ L++ A +Y+R+G+ + +++S NR Y IC +YP L VP
Sbjct: 1113 SDRMTMSSLVERACCRDYQRLGLGTLSSSLSRAKSEPFRISPVNRMYAICRSYPGLLIVP 1172
Query: 167 RIASKPIIVGSSKFRSKGRFPVLSYYHQDKEAAICRC---------------SQPLSGFS 211
+ + S+ + RFPV+ + +A + R + P G S
Sbjct: 1173 QSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVLLRSGGLHGKGVVGLFKAQNAPSPGQS 1232
Query: 212 ---ARCLEDEHLLQAISKANP 229
+ LE E LQA+ + P
Sbjct: 1233 QADSSSLEQEKYLQAVVSSMP 1253
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 118 bits (296), Expect = 1e-26
Identities = 120/483 (24%), Positives = 198/483 (40%), Gaps = 109/483 (22%)
Query: 119 SERLQGWQLIDLA--EEYKRMGVPN----------SHWQLSDANRDYKICETYPRELYVP 166
SE+ QL++ A +Y+R+G+ +++++ +NR Y +C +YP L VP
Sbjct: 1101 SEKSTMEQLVEKACFRDYQRLGLGTISGSSSRSRPEYFRITASNRMYSLCRSYPGLLVVP 1160
Query: 167 RIASKPIIVGSSKFRSKGRFPVLSYYHQDKEAAICRC-------------------SQPL 207
+ + ++ R PV+ + + + R + P
Sbjct: 1161 QAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAAPT 1220
Query: 208 SGF-SARCLEDEHLLQAISKANPVNRYM---YVMDTRPKLNA------------------ 245
S S+ +E E LQA+ A V++ + + RP
Sbjct: 1221 SSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLTVRPAFALSPGVWASLRSSTRLISSP 1280
Query: 246 -----MANRAAGK----GYENEDNYSN--------------------------IRFQFVG 270
+ R AGK + N N + +FV
Sbjct: 1281 TSFIDVGARLAGKDHSASFSNSSYLQNQLLKRQAALYIFGEKSQLRNFKVEFALNCEFVP 1340
Query: 271 IE--NIHVMRSSLQKLLEVNGTKGLSVND---FYSGLESSGWLRHIKAVMDAAIFLAKAI 325
+E I +++S +KL+ + + F L S W + +M A+ +++ +
Sbjct: 1341 VEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVL 1400
Query: 326 TVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWISFGHKFSERCG- 384
+SVLV +GWD T+QV SL LL D +YRT++GF +L+EK+W+SFGHKFS+R
Sbjct: 1401 E-NGSSVLVCLEEGWDITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKFSQRSSL 1459
Query: 385 QLDGDPKEVSPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKE 444
L+ +PVF QFL+CV + Q+P FEF+ +L + H S +F FL + E
Sbjct: 1460 TLNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYE 1519
Query: 445 REE---------LKLKEKTYSLWPFLLEDQKK---YLNPLYSSESHRFTVLEPNTVSFNF 492
R E K +K +W + K+ + N LYS L+PN +
Sbjct: 1520 RLEHGTLFDDKGEKHAKKGVCIWECIDRMHKRSPIFFNYLYS--PLEIEALKPNVNVSSL 1577
Query: 493 KFW 495
K W
Sbjct: 1578 KKW 1580
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 118 bits (295), Expect = 2e-26
Identities = 117/431 (27%), Positives = 192/431 (44%), Gaps = 53/431 (12%)
Query: 68 LVIQCKNFRTVHFIV--PRERDCHDIYNSLLQLSKQAKY-EDLYAFSY-NPKQNDS---- 119
L+I CK+ R F + +E + I + ++ ++ K + L+ FSY QN++
Sbjct: 139 LIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDP 198
Query: 120 --ERLQGWQLIDLAEEYKRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGS 177
+ L D E +R N ++ N YK+CE P VP + +
Sbjct: 199 KNHTVMFDTLKDWCWELERTK-GNMKYKAVSVNEGYKVCERLPAYFVVPTPLPEENV--- 254
Query: 178 SKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNRYMYVM 237
+F+ G P+ + + A + + P +D+ +LQ I K+ Y +
Sbjct: 255 QRFQGHG-IPIWCWSCHNGSALLKMSALPKE-------QDDGILQ-IQKSFLDGIYKTIH 305
Query: 238 DTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVND 297
RP + + ED SN F+ ++ I S ++L ++ + D
Sbjct: 306 --RPPYEIV---------KTEDLSSN----FLSLQEIQTAYSKFKQLFLIDNSTEFWDTD 350
Query: 298 --FYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLD 355
++S LESS WL I+ + AI + + + +N +VL+ + D + SL L++D
Sbjct: 351 IKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMMD 410
Query: 356 SYYRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQFPQAF 415
+ RT GF LI+K+W+ GH F +RC L + KE PVF FL+CVW L Q P AF
Sbjct: 411 PHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAF 470
Query: 416 EFSEAFLLQIHEHIHSCQFGNFLGNC--QKE----REELKLKEKTYSL-----WPFLLED 464
EF+E +L + + ++ F F N QK+ RE + K +L W E
Sbjct: 471 EFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDWSVQFEP 530
Query: 465 QKKYL--NPLY 473
+ + L NPLY
Sbjct: 531 KAQTLLKNPLY 541
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 99.4 bits (246), Expect = 9e-21
Identities = 87/334 (26%), Positives = 148/334 (44%), Gaps = 39/334 (11%)
Query: 116 QNDSERLQGWQLIDLAEEYK--RMGVPNSHWQLSDANRDYKICETYPRELYVP-RIASKP 172
Q R L++ AE+++ R W++S N + + + PR +VP RI
Sbjct: 184 QGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSE 243
Query: 173 IIVGSSKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNR 232
+ F +GR P LS++H + + RC GF ++ ++A+
Sbjct: 244 VRRAFGHFH-QGRGPRLSWHHPGG-SDLLRCG----GFYTASDPNKEDIRAVELMLQAGH 297
Query: 233 YMYVM-DTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTK 291
V+ DT +L ++A+ ++ + + + + SS+ +
Sbjct: 298 SDVVLVDTMDELPSLAD---------------VQLAHLRLRALCLPDSSVAE-------- 334
Query: 292 GLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGS 351
+ + S LE + WL +++A + A ++ +T SV++ D + SL
Sbjct: 335 ----DKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQ 390
Query: 352 LLLDSYYRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQF 411
LL RT+ GF L++++W++ GH F R G E +PVF FL+CVW L +QF
Sbjct: 391 LLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGAS--EEAPVFLLFLDCVWQLLQQF 448
Query: 412 PQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKER 445
P FEFSE FLL +H+ + FL N ER
Sbjct: 449 PADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 482
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 99.4 bits (246), Expect = 9e-21
Identities = 87/334 (26%), Positives = 148/334 (44%), Gaps = 39/334 (11%)
Query: 116 QNDSERLQGWQLIDLAEEYK--RMGVPNSHWQLSDANRDYKICETYPRELYVP-RIASKP 172
Q R L++ AE+++ R W++S N + + + PR +VP RI
Sbjct: 112 QGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSE 171
Query: 173 IIVGSSKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCLEDEHLLQAISKANPVNR 232
+ F +GR P LS++H + + RC GF ++ ++A+
Sbjct: 172 VRRAFGHFH-QGRGPRLSWHHPGG-SDLLRCG----GFYTASDPNKEDIRAVELMLQAGH 225
Query: 233 YMYVM-DTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTK 291
V+ DT +L ++A+ ++ + + + + SS+ +
Sbjct: 226 SDVVLVDTMDELPSLAD---------------VQLAHLRLRALCLPDSSVAE-------- 262
Query: 292 GLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGS 351
+ + S LE + WL +++A + A ++ +T SV++ D + SL
Sbjct: 263 ----DKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQ 318
Query: 352 LLLDSYYRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSPVFTQFLECVWHLTEQF 411
LL RT+ GF L++++W++ GH F R G E +PVF FL+CVW L +QF
Sbjct: 319 LLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGAS--EEAPVFLLFLDCVWQLLQQF 376
Query: 412 PQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKER 445
P FEFSE FLL +H+ + FL N ER
Sbjct: 377 PADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
>gi|117938274 jumpy isoform 3 [Homo sapiens]
Length = 538
Score = 37.0 bits (84), Expect = 0.054
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
Query: 328 ENASVLVHCSDGWDRTSQVCSLGSL------LLDSYYRTIKGFMVLIEKDWISFGHKFSE 381
+++ +LVHC GWDRT SL L L+ + + + + + DW FGH +
Sbjct: 322 DDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVD 381
Query: 382 R 382
R
Sbjct: 382 R 382
>gi|117938272 jumpy isoform 1 [Homo sapiens]
Length = 598
Score = 37.0 bits (84), Expect = 0.054
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
Query: 328 ENASVLVHCSDGWDRTSQVCSLGSL------LLDSYYRTIKGFMVLIEKDWISFGHKFSE 381
+++ +LVHC GWDRT SL L L+ + + + + + DW FGH +
Sbjct: 322 DDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVD 381
Query: 382 R 382
R
Sbjct: 382 R 382
>gi|117938270 jumpy isoform 2 [Homo sapiens]
Length = 650
Score = 37.0 bits (84), Expect = 0.054
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
Query: 328 ENASVLVHCSDGWDRTSQVCSLGSL------LLDSYYRTIKGFMVLIEKDWISFGHKFSE 381
+++ +LVHC GWDRT SL L L+ + + + + + DW FGH +
Sbjct: 322 DDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVD 381
Query: 382 R 382
R
Sbjct: 382 R 382
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 35.0 bits (79), Expect = 0.21
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 516 IMNMNEQNKQLEKDIKDLESKIKQRKNKQTDGILTKELLHSVHPESPNLKTSLCFKEQTL 575
++N+N Q KQ ++ L + KQR ++ + ++ K S + KT E TL
Sbjct: 737 LINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTL 796
Query: 576 LPVNDALRTIEGSSPADNRYSEYAEEFSKSEPAVVSLEYGVARM 619
N L+ IE EY ++ +KS + L+ ++ +
Sbjct: 797 EKANSKLKQIE---------KEYTQKLAKSSQIIAELQTTISSL 831
>gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 2 [Homo sapiens]
Length = 595
Score = 34.3 bits (77), Expect = 0.35
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 500 HQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQT 545
H+ R L QSVF + N N+ QLE+ +K+L+ K+ + K +T
Sbjct: 353 HEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKETET 398
>gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 2 [Homo sapiens]
Length = 595
Score = 34.3 bits (77), Expect = 0.35
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 500 HQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQT 545
H+ R L QSVF + N N+ QLE+ +K+L+ K+ + K +T
Sbjct: 353 HEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKETET 398
>gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 595
Score = 34.3 bits (77), Expect = 0.35
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 500 HQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQT 545
H+ R L QSVF + N N+ QLE+ +K+L+ K+ + K +T
Sbjct: 353 HEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKETET 398
>gi|169208016 PREDICTED: similar to golgi autoantigen, golgin
subfamily a, 8E isoform 1 [Homo sapiens]
Length = 594
Score = 34.3 bits (77), Expect = 0.35
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 500 HQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQT 545
H+ R L QSVF + N N+ QLE+ +K+L+ K+ + K +T
Sbjct: 352 HEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKETET 397
>gi|24497453 nucleoporin 88kDa [Homo sapiens]
Length = 741
Score = 33.9 bits (76), Expect = 0.46
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 6/100 (6%)
Query: 521 EQNKQLEKDIKDLESKIKQRKNKQTDGI-LTKELLHSVHPESPNLKTSLCFKEQTLLPVN 579
E+ K L + + L K ++ K KQ D + K+LLHS H E P L S ++ L +
Sbjct: 610 EERKSLREMAERLADKYEEAKEKQEDIMNRMKKLLHSFHSELPVLSDSERDMKKELQLIP 669
Query: 580 DALRTIEGSSPADNRYSEYAEE-----FSKSEPAVVSLEY 614
D LR + + +Y ++ S +P ++ Y
Sbjct: 670 DQLRHLGNAIKQVTMKKDYQQQKMEKVLSLPKPTIILSAY 709
>gi|125490354 spermatogenesis associated 1 [Homo sapiens]
Length = 459
Score = 33.9 bits (76), Expect = 0.46
Identities = 40/162 (24%), Positives = 72/162 (44%), Gaps = 14/162 (8%)
Query: 443 KEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFNFKFWRNMYHQF 502
KE++E +LK K+++ P+ L+ + YL P+ H V P+TV + + N ++
Sbjct: 111 KEKQESELKLKSFAP-PYALQPEL-YLLPVMD---HLGNVYSPSTVILDERQTNNGVNEA 165
Query: 503 DRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQ----RKNKQTDGILTKELLHSVH 558
D T+H SV + LE +K+L +K ++ + + I ++ +S
Sbjct: 166 DGTIHRPISVTLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSEL 225
Query: 559 PESPNLKTSLCF---KEQTLLPVND--ALRTIEGSSPADNRY 595
P S + CF K Q L D A+ + + A+ Y
Sbjct: 226 PGSLEDSNNDCFGTKKSQCLWENEDDTAISRRQDNQTAEKEY 267
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 33.1 bits (74), Expect = 0.78
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 11/83 (13%)
Query: 534 ESKIKQRKNKQTDGILTKELLHSVH-PESPNLKTSLCFKEQTLLPVNDALRT--IEGSSP 590
ES++K+R K+ ++++HS+H PNL C Q LL + LR+ IE ++
Sbjct: 1014 ESQLKERLEKRY-----QDIIHSIHLARKPNLGLKSCDGNQELL---NFLRSDLIEVATR 1065
Query: 591 ADNRYSEYAEEFSKSEPAVVSLE 613
Y EE S+ E V+SLE
Sbjct: 1066 LQKGGLGYVEETSEFEARVISLE 1088
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,252,033
Number of Sequences: 37866
Number of extensions: 1049679
Number of successful extensions: 3249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 3103
Number of HSP's gapped (non-prelim): 134
length of query: 621
length of database: 18,247,518
effective HSP length: 108
effective length of query: 513
effective length of database: 14,157,990
effective search space: 7263048870
effective search space used: 7263048870
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.