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Search of human proteins with 134142062
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
(2458 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens] 4934 0.0
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 3538 0.0
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 3538 0.0
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ... 3538 0.0
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ... 3533 0.0
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ... 3530 0.0
gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide ... 246 3e-64
gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide... 245 4e-64
gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) pr... 235 4e-61
gi|106049528 pyruvate carboxylase precursor [Homo sapiens] 215 4e-55
gi|106049295 pyruvate carboxylase precursor [Homo sapiens] 215 4e-55
gi|106049292 pyruvate carboxylase precursor [Homo sapiens] 215 4e-55
gi|119943100 propionyl Coenzyme A carboxylase, beta polypeptide ... 79 4e-14
gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarba... 66 4e-10
gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo sa... 54 2e-06
gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precurso... 54 2e-06
gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor... 54 2e-06
gi|11545863 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) [Hom... 48 1e-04
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 43 0.003
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 43 0.003
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 43 0.003
gi|19924103 synapsin II isoform IIa [Homo sapiens] 42 0.007
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 42 0.007
gi|164663810 ribosomal modification protein rimK-like family mem... 41 0.013
gi|167736355 mucin 4 isoform a [Homo sapiens] 41 0.017
gi|21361684 G patch domain containing 1 [Homo sapiens] 41 0.017
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 40 0.037
gi|209862975 MAP-kinase activating death domain-containing prote... 39 0.048
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 39 0.048
gi|49472835 bridging integrator 2 [Homo sapiens] 39 0.063
>gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
Length = 2458
Score = 4934 bits (12797), Expect = 0.0
Identities = 2458/2458 (100%), Positives = 2458/2458 (100%)
Query: 1 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR 60
MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR
Sbjct: 1 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR 60
Query: 61 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT 120
NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT
Sbjct: 61 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT 120
Query: 121 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV 180
GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV
Sbjct: 121 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV 180
Query: 181 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR 240
AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR
Sbjct: 181 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR 240
Query: 241 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT 300
DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT
Sbjct: 241 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT 300
Query: 301 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL 360
PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL
Sbjct: 301 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL 360
Query: 361 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK 420
PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK
Sbjct: 361 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK 420
Query: 421 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV 480
RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV
Sbjct: 421 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV 480
Query: 481 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP 540
QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP
Sbjct: 481 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP 540
Query: 541 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL 600
LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL
Sbjct: 541 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL 600
Query: 601 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE 660
PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE
Sbjct: 601 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE 660
Query: 661 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA 720
GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA
Sbjct: 661 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA 720
Query: 721 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL 780
LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL
Sbjct: 721 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL 780
Query: 781 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM 840
NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM
Sbjct: 781 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM 840
Query: 841 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP 900
NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP
Sbjct: 841 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP 900
Query: 901 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR 960
SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR
Sbjct: 901 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR 960
Query: 961 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK 1020
LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK
Sbjct: 961 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK 1020
Query: 1021 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP 1080
LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP
Sbjct: 1021 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP 1080
Query: 1081 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV 1140
SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV
Sbjct: 1081 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV 1140
Query: 1141 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD 1200
EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD
Sbjct: 1141 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD 1200
Query: 1201 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP 1260
ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP
Sbjct: 1201 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP 1260
Query: 1261 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV 1320
ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV
Sbjct: 1261 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV 1320
Query: 1321 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR 1380
VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR
Sbjct: 1321 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR 1380
Query: 1381 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP 1440
NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP
Sbjct: 1381 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP 1440
Query: 1441 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL 1500
ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL
Sbjct: 1441 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL 1500
Query: 1501 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY 1560
ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY
Sbjct: 1501 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY 1560
Query: 1561 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS 1620
LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS
Sbjct: 1561 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS 1620
Query: 1621 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF 1680
RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF
Sbjct: 1621 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF 1680
Query: 1681 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK 1740
GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK
Sbjct: 1681 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK 1740
Query: 1741 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG 1800
DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG
Sbjct: 1741 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG 1800
Query: 1801 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK 1860
SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK
Sbjct: 1801 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK 1860
Query: 1861 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL 1920
YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL
Sbjct: 1861 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL 1920
Query: 1921 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL 1980
AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL
Sbjct: 1921 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL 1980
Query: 1981 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR 2040
GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR
Sbjct: 1981 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR 2040
Query: 2041 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE 2100
APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE
Sbjct: 2041 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE 2100
Query: 2101 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF 2160
TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF
Sbjct: 2101 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF 2160
Query: 2161 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA 2220
SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA
Sbjct: 2161 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA 2220
Query: 2221 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK 2280
DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK
Sbjct: 2221 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK 2280
Query: 2281 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK 2340
AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK
Sbjct: 2281 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK 2340
Query: 2341 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR 2400
QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR
Sbjct: 2341 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR 2400
Query: 2401 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2458
ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST
Sbjct: 2401 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2458
>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 3538 bits (9173), Expect = 0.0
Identities = 1749/2334 (74%), Positives = 2009/2334 (86%), Gaps = 43/2334 (1%)
Query: 163 TNFILGSFDDYSSDEDSVAGSSR-----ESTRKGSRASLGALSLEAYLTTGEAETRVPTM 217
+ FI+GS + +S ED ++ + E S AS+G+ +L + + +
Sbjct: 17 SRFIIGSVSEDNS-EDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHI 75
Query: 218 RPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMR 277
R SMSGLHLVK+GR+ KK+D RDFTVASPAEFVTRFGG++VIEKVLIANNGIAAVKCMR
Sbjct: 76 RSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMR 135
Query: 278 SIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVD 337
SIRRW+YEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELI+D
Sbjct: 136 SIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILD 195
Query: 338 IAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQV 397
IAKRIPVQAVWAGWGHASENPKLPELL KNG+AF+GPPS+AMWALGDKIAS++VAQT +
Sbjct: 196 IAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGI 255
Query: 398 PTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASE 457
PTLPWSGSGL V+W E+D + + ++VP+++Y+KG VKDVD+GL+AAE +G+P+MIKASE
Sbjct: 256 PTLPWSGSGLRVDWQENDFSK-RILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASE 314
Query: 458 GGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLF 517
GGGGKGIRK +A+DFP LFRQVQ+E+PGSPIF+M+LA+ +RHLEVQILADQYGNA+SLF
Sbjct: 315 GGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLF 374
Query: 518 GRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFH 577
GRDCS+QRRHQKI+EEAPATIA A+FE MEQCA++LAK VGYVSAGTVEYLYSQDGSF+
Sbjct: 375 GRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFY 434
Query: 578 FLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFET 637
FLELNPRLQVEHPCTEM+ADVNLPAAQLQIAMG+PL+R+KDIR++YG SPWG +PI FE
Sbjct: 435 FLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFED 494
Query: 638 PSNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFAD 697
++ P RGHVIAARITSENPDEGFKPSSGTVQELNFRS+KNVWGYFSVAA GGLHEFAD
Sbjct: 495 SAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFAD 554
Query: 698 SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLD 757
SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLI LLETESFQ N IDTGWLD
Sbjct: 555 SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLD 614
Query: 758 YLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVEL 817
LIAEKVQAE+PD MLGVVCGAL+VAD R +++FLHSLERGQVLPA +LLN VDVEL
Sbjct: 615 RLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVEL 674
Query: 818 IYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSY 877
IY GVKY+LKV RQS +V+IMNG +E+D HRL+DGGLLLSY+G+SYTTYMKEEVD Y
Sbjct: 675 IYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRY 734
Query: 878 RITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQ 937
RITIGNKTCVFEKENDP+V+RSPSAGKL QY VEDGGHV AG YAE+EVMKM+MTL
Sbjct: 735 RITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAV 794
Query: 938 ERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFH 997
E G + Y+KRPGA L+ GCV+A+++LD+PSKV AE TG LP Q+ + GEKLH+VFH
Sbjct: 795 ESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFH 854
Query: 998 SVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPV 1057
VL+NL NVM+G+CLP+P FS K+K+WV++LM TLR PSLPLLELQ+IMTSV+GRIP V
Sbjct: 855 YVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNV 914
Query: 1058 EKSVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFINTQSIVQLVQR 1117
EKS+++ MAQYASNITSVLCQFPSQQIA ILD HAATL RK++REVFF+NTQSIVQLVQR
Sbjct: 915 EKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQR 974
Query: 1118 YRSGIRGYMKTVVLDLLRRYLRVEHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQV 1177
YRSGIRG+MK VV+DLLR+YLRVE FQ HYDKCV LRE+ K DM+ VL+ IFSHAQV
Sbjct: 975 YRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQV 1034
Query: 1178 AKKNQLVIMLIDELCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYE 1237
KKN LV MLID+LCG DP+L+DEL++IL ELTQLSK+ + KVALRARQ+LIASHLPSYE
Sbjct: 1035 TKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYE 1094
Query: 1238 LRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYV 1297
LRHNQVESIFLSAIDMYGHQFC ENL+KLILSET+IFDVLP FFYH+N+VV MA+LEVYV
Sbjct: 1095 LRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYV 1154
Query: 1298 RRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMTVPI--SITNPDLLRH------ 1349
RR YIAYELNS+QHRQL D TCVVEFQFMLP+SHPNR +P ++ L H
Sbjct: 1155 RRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHV 1214
Query: 1350 --STELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEA-RTSL 1406
+++ +D+ F+P CQRMG MV+FR FEDF R FDEV+ CF++ P +P F EA TSL
Sbjct: 1215 ASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSL 1274
Query: 1407 YSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNILVDYGLRRITFLIA 1466
Y ED K R+EPIHILNV+I+ +ED+ L + R F Q K LVD+G+RR+TFL+A
Sbjct: 1275 YDED--KVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVA 1332
Query: 1467 QE---------------KEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLT 1511
Q+ +EFPKFFTFRARD+F EDRIYRHLEPALAFQLELNRMRNFDLT
Sbjct: 1333 QKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLT 1392
Query: 1512 AVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLE 1571
A+PCANHKMHLYLGAAKV+ G EVTD+RFF+RAIIRHSDL+TKEASFEYLQNEGERLLLE
Sbjct: 1393 AIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLE 1452
Query: 1572 AMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAE 1631
AMDELEVAFNNT+VRTDCNHIFLNFVPTVIMDP KIEESVR MVMRYGSRLWKLRVLQAE
Sbjct: 1453 AMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAE 1512
Query: 1632 VKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGML 1691
+KINIR T TG A+PIRLF+TNESGYYLDISLYKEVTDSR+ IMF ++G+KQGP HGML
Sbjct: 1513 LKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGML 1572
Query: 1692 INTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGS--------PDKYPKDIL 1743
INTPYVTKDLLQ+KRFQAQ+LGTTYIYD PEMFRQ+L KLW S P D+L
Sbjct: 1573 INTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDML 1632
Query: 1744 TYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFG 1803
TYTELVLD QGQLV MNRLPGGNE+GMVA+KM FK+ EYPEGRD+IVIGNDIT+RIGSFG
Sbjct: 1633 TYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFG 1692
Query: 1804 PGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLY 1863
P EDLL+LRASE+ARAEGIP+IYV+ANSGARIG+AEEI+HMFHVAWVDPEDP+KG++YLY
Sbjct: 1693 PQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLY 1752
Query: 1864 LTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYE 1923
LTPQDY R+S+LNSVHC+H+E+ GESRY ITDIIGK++G+G ENLRGSGMIAGESSLAY
Sbjct: 1753 LTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYN 1812
Query: 1924 EIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGV 1983
EI+TISLVTCRAIGIGAYLVRLGQR IQVENSH+ILTGA ALNKVLGREVYTSNNQLGG+
Sbjct: 1813 EIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGI 1872
Query: 1984 QIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPY 2043
QIMH NGV+H TV DDFEGV+T+L WLSYMPK HS VP++ DPIDR IEF+P++ PY
Sbjct: 1873 QIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKTPY 1932
Query: 2044 DPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRT 2103
DPRWMLAGRPHPT KG W SGFFD+GSF EIM PWAQTVV GRARLGGIPVGV+AVETRT
Sbjct: 1933 DPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRT 1992
Query: 2104 VEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGG 2163
VE+++PADPANLDSEAKIIQQAGQVWFPDSA+KT QA+KDFNRE LPLM+FANWRGFSGG
Sbjct: 1993 VELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGG 2052
Query: 2164 MKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKE 2223
MKDMYDQVLKFGAYIVDGLR+ QP+L+YIPP AELRGGSWVVID++INP +EMYAD+E
Sbjct: 2053 MKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRE 2112
Query: 2224 SRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKARE 2283
SRG VLEPEGTVEIKFR+KDL+K+MRR+DP Y L E+LG P+LS +RK+LE +LK RE
Sbjct: 2113 SRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAERKELENKLKERE 2172
Query: 2284 DLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEI 2343
+ L+PIYHQVAVQFAD HDTPGRM EKGVISDIL+WKT+RTF YWRLRRLLLED VK++I
Sbjct: 2173 EFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKI 2232
Query: 2344 LQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENI 2403
A+ EL+ IQ+MLRRWFVE EG VKAY+WDNN+ + +WLE+ DG S I ENI
Sbjct: 2233 HNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENI 2292
Query: 2404 TYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAS 2457
+ D VLK IR LV+ NPEVA+D +I+++QHISP +RA+V+ +LSTMDSP++
Sbjct: 2293 KCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST 2346
>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 3538 bits (9173), Expect = 0.0
Identities = 1749/2334 (74%), Positives = 2009/2334 (86%), Gaps = 43/2334 (1%)
Query: 163 TNFILGSFDDYSSDEDSVAGSSR-----ESTRKGSRASLGALSLEAYLTTGEAETRVPTM 217
+ FI+GS + +S ED ++ + E S AS+G+ +L + + +
Sbjct: 17 SRFIIGSVSEDNS-EDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHI 75
Query: 218 RPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMR 277
R SMSGLHLVK+GR+ KK+D RDFTVASPAEFVTRFGG++VIEKVLIANNGIAAVKCMR
Sbjct: 76 RSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMR 135
Query: 278 SIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVD 337
SIRRW+YEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELI+D
Sbjct: 136 SIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILD 195
Query: 338 IAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQV 397
IAKRIPVQAVWAGWGHASENPKLPELL KNG+AF+GPPS+AMWALGDKIAS++VAQT +
Sbjct: 196 IAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGI 255
Query: 398 PTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASE 457
PTLPWSGSGL V+W E+D + + ++VP+++Y+KG VKDVD+GL+AAE +G+P+MIKASE
Sbjct: 256 PTLPWSGSGLRVDWQENDFSK-RILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASE 314
Query: 458 GGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLF 517
GGGGKGIRK +A+DFP LFRQVQ+E+PGSPIF+M+LA+ +RHLEVQILADQYGNA+SLF
Sbjct: 315 GGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLF 374
Query: 518 GRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFH 577
GRDCS+QRRHQKI+EEAPATIA A+FE MEQCA++LAK VGYVSAGTVEYLYSQDGSF+
Sbjct: 375 GRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFY 434
Query: 578 FLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFET 637
FLELNPRLQVEHPCTEM+ADVNLPAAQLQIAMG+PL+R+KDIR++YG SPWG +PI FE
Sbjct: 435 FLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFED 494
Query: 638 PSNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFAD 697
++ P RGHVIAARITSENPDEGFKPSSGTVQELNFRS+KNVWGYFSVAA GGLHEFAD
Sbjct: 495 SAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFAD 554
Query: 698 SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLD 757
SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLI LLETESFQ N IDTGWLD
Sbjct: 555 SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLD 614
Query: 758 YLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVEL 817
LIAEKVQAE+PD MLGVVCGAL+VAD R +++FLHSLERGQVLPA +LLN VDVEL
Sbjct: 615 RLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVEL 674
Query: 818 IYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSY 877
IY GVKY+LKV RQS +V+IMNG +E+D HRL+DGGLLLSY+G+SYTTYMKEEVD Y
Sbjct: 675 IYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRY 734
Query: 878 RITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQ 937
RITIGNKTCVFEKENDP+V+RSPSAGKL QY VEDGGHV AG YAE+EVMKM+MTL
Sbjct: 735 RITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAV 794
Query: 938 ERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFH 997
E G + Y+KRPGA L+ GCV+A+++LD+PSKV AE TG LP Q+ + GEKLH+VFH
Sbjct: 795 ESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFH 854
Query: 998 SVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPV 1057
VL+NL NVM+G+CLP+P FS K+K+WV++LM TLR PSLPLLELQ+IMTSV+GRIP V
Sbjct: 855 YVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNV 914
Query: 1058 EKSVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFINTQSIVQLVQR 1117
EKS+++ MAQYASNITSVLCQFPSQQIA ILD HAATL RK++REVFF+NTQSIVQLVQR
Sbjct: 915 EKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQR 974
Query: 1118 YRSGIRGYMKTVVLDLLRRYLRVEHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQV 1177
YRSGIRG+MK VV+DLLR+YLRVE FQ HYDKCV LRE+ K DM+ VL+ IFSHAQV
Sbjct: 975 YRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQV 1034
Query: 1178 AKKNQLVIMLIDELCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYE 1237
KKN LV MLID+LCG DP+L+DEL++IL ELTQLSK+ + KVALRARQ+LIASHLPSYE
Sbjct: 1035 TKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYE 1094
Query: 1238 LRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYV 1297
LRHNQVESIFLSAIDMYGHQFC ENL+KLILSET+IFDVLP FFYH+N+VV MA+LEVYV
Sbjct: 1095 LRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYV 1154
Query: 1298 RRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMTVPI--SITNPDLLRH------ 1349
RR YIAYELNS+QHRQL D TCVVEFQFMLP+SHPNR +P ++ L H
Sbjct: 1155 RRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHV 1214
Query: 1350 --STELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEA-RTSL 1406
+++ +D+ F+P CQRMG MV+FR FEDF R FDEV+ CF++ P +P F EA TSL
Sbjct: 1215 ASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSL 1274
Query: 1407 YSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNILVDYGLRRITFLIA 1466
Y ED K R+EPIHILNV+I+ +ED+ L + R F Q K LVD+G+RR+TFL+A
Sbjct: 1275 YDED--KVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVA 1332
Query: 1467 QE---------------KEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLT 1511
Q+ +EFPKFFTFRARD+F EDRIYRHLEPALAFQLELNRMRNFDLT
Sbjct: 1333 QKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLT 1392
Query: 1512 AVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLE 1571
A+PCANHKMHLYLGAAKV+ G EVTD+RFF+RAIIRHSDL+TKEASFEYLQNEGERLLLE
Sbjct: 1393 AIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLE 1452
Query: 1572 AMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAE 1631
AMDELEVAFNNT+VRTDCNHIFLNFVPTVIMDP KIEESVR MVMRYGSRLWKLRVLQAE
Sbjct: 1453 AMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAE 1512
Query: 1632 VKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGML 1691
+KINIR T TG A+PIRLF+TNESGYYLDISLYKEVTDSR+ IMF ++G+KQGP HGML
Sbjct: 1513 LKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGML 1572
Query: 1692 INTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGS--------PDKYPKDIL 1743
INTPYVTKDLLQ+KRFQAQ+LGTTYIYD PEMFRQ+L KLW S P D+L
Sbjct: 1573 INTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDML 1632
Query: 1744 TYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFG 1803
TYTELVLD QGQLV MNRLPGGNE+GMVA+KM FK+ EYPEGRD+IVIGNDIT+RIGSFG
Sbjct: 1633 TYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFG 1692
Query: 1804 PGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLY 1863
P EDLL+LRASE+ARAEGIP+IYV+ANSGARIG+AEEI+HMFHVAWVDPEDP+KG++YLY
Sbjct: 1693 PQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLY 1752
Query: 1864 LTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYE 1923
LTPQDY R+S+LNSVHC+H+E+ GESRY ITDIIGK++G+G ENLRGSGMIAGESSLAY
Sbjct: 1753 LTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYN 1812
Query: 1924 EIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGV 1983
EI+TISLVTCRAIGIGAYLVRLGQR IQVENSH+ILTGA ALNKVLGREVYTSNNQLGG+
Sbjct: 1813 EIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGI 1872
Query: 1984 QIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPY 2043
QIMH NGV+H TV DDFEGV+T+L WLSYMPK HS VP++ DPIDR IEF+P++ PY
Sbjct: 1873 QIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKTPY 1932
Query: 2044 DPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRT 2103
DPRWMLAGRPHPT KG W SGFFD+GSF EIM PWAQTVV GRARLGGIPVGV+AVETRT
Sbjct: 1933 DPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRT 1992
Query: 2104 VEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGG 2163
VE+++PADPANLDSEAKIIQQAGQVWFPDSA+KT QA+KDFNRE LPLM+FANWRGFSGG
Sbjct: 1993 VELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGG 2052
Query: 2164 MKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKE 2223
MKDMYDQVLKFGAYIVDGLR+ QP+L+YIPP AELRGGSWVVID++INP +EMYAD+E
Sbjct: 2053 MKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRE 2112
Query: 2224 SRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKARE 2283
SRG VLEPEGTVEIKFR+KDL+K+MRR+DP Y L E+LG P+LS +RK+LE +LK RE
Sbjct: 2113 SRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAERKELENKLKERE 2172
Query: 2284 DLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEI 2343
+ L+PIYHQVAVQFAD HDTPGRM EKGVISDIL+WKT+RTF YWRLRRLLLED VK++I
Sbjct: 2173 EFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKI 2232
Query: 2344 LQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENI 2403
A+ EL+ IQ+MLRRWFVE EG VKAY+WDNN+ + +WLE+ DG S I ENI
Sbjct: 2233 HNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENI 2292
Query: 2404 TYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAS 2457
+ D VLK IR LV+ NPEVA+D +I+++QHISP +RA+V+ +LSTMDSP++
Sbjct: 2293 KCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST 2346
>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
sapiens]
Length = 2383
Score = 3538 bits (9173), Expect = 0.0
Identities = 1749/2334 (74%), Positives = 2009/2334 (86%), Gaps = 43/2334 (1%)
Query: 163 TNFILGSFDDYSSDEDSVAGSSR-----ESTRKGSRASLGALSLEAYLTTGEAETRVPTM 217
+ FI+GS + +S ED ++ + E S AS+G+ +L + + +
Sbjct: 54 SRFIIGSVSEDNS-EDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHI 112
Query: 218 RPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMR 277
R SMSGLHLVK+GR+ KK+D RDFTVASPAEFVTRFGG++VIEKVLIANNGIAAVKCMR
Sbjct: 113 RSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMR 172
Query: 278 SIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVD 337
SIRRW+YEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELI+D
Sbjct: 173 SIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILD 232
Query: 338 IAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQV 397
IAKRIPVQAVWAGWGHASENPKLPELL KNG+AF+GPPS+AMWALGDKIAS++VAQT +
Sbjct: 233 IAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGI 292
Query: 398 PTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASE 457
PTLPWSGSGL V+W E+D + + ++VP+++Y+KG VKDVD+GL+AAE +G+P+MIKASE
Sbjct: 293 PTLPWSGSGLRVDWQENDFSK-RILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASE 351
Query: 458 GGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLF 517
GGGGKGIRK +A+DFP LFRQVQ+E+PGSPIF+M+LA+ +RHLEVQILADQYGNA+SLF
Sbjct: 352 GGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLF 411
Query: 518 GRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFH 577
GRDCS+QRRHQKI+EEAPATIA A+FE MEQCA++LAK VGYVSAGTVEYLYSQDGSF+
Sbjct: 412 GRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFY 471
Query: 578 FLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFET 637
FLELNPRLQVEHPCTEM+ADVNLPAAQLQIAMG+PL+R+KDIR++YG SPWG +PI FE
Sbjct: 472 FLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFED 531
Query: 638 PSNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFAD 697
++ P RGHVIAARITSENPDEGFKPSSGTVQELNFRS+KNVWGYFSVAA GGLHEFAD
Sbjct: 532 SAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFAD 591
Query: 698 SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLD 757
SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLI LLETESFQ N IDTGWLD
Sbjct: 592 SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLD 651
Query: 758 YLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVEL 817
LIAEKVQAE+PD MLGVVCGAL+VAD R +++FLHSLERGQVLPA +LLN VDVEL
Sbjct: 652 RLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVEL 711
Query: 818 IYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSY 877
IY GVKY+LKV RQS +V+IMNG +E+D HRL+DGGLLLSY+G+SYTTYMKEEVD Y
Sbjct: 712 IYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRY 771
Query: 878 RITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQ 937
RITIGNKTCVFEKENDP+V+RSPSAGKL QY VEDGGHV AG YAE+EVMKM+MTL
Sbjct: 772 RITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAV 831
Query: 938 ERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFH 997
E G + Y+KRPGA L+ GCV+A+++LD+PSKV AE TG LP Q+ + GEKLH+VFH
Sbjct: 832 ESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFH 891
Query: 998 SVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPV 1057
VL+NL NVM+G+CLP+P FS K+K+WV++LM TLR PSLPLLELQ+IMTSV+GRIP V
Sbjct: 892 YVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNV 951
Query: 1058 EKSVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFINTQSIVQLVQR 1117
EKS+++ MAQYASNITSVLCQFPSQQIA ILD HAATL RK++REVFF+NTQSIVQLVQR
Sbjct: 952 EKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQR 1011
Query: 1118 YRSGIRGYMKTVVLDLLRRYLRVEHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQV 1177
YRSGIRG+MK VV+DLLR+YLRVE FQ HYDKCV LRE+ K DM+ VL+ IFSHAQV
Sbjct: 1012 YRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQV 1071
Query: 1178 AKKNQLVIMLIDELCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYE 1237
KKN LV MLID+LCG DP+L+DEL++IL ELTQLSK+ + KVALRARQ+LIASHLPSYE
Sbjct: 1072 TKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYE 1131
Query: 1238 LRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYV 1297
LRHNQVESIFLSAIDMYGHQFC ENL+KLILSET+IFDVLP FFYH+N+VV MA+LEVYV
Sbjct: 1132 LRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYV 1191
Query: 1298 RRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMTVPI--SITNPDLLRH------ 1349
RR YIAYELNS+QHRQL D TCVVEFQFMLP+SHPNR +P ++ L H
Sbjct: 1192 RRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHV 1251
Query: 1350 --STELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEA-RTSL 1406
+++ +D+ F+P CQRMG MV+FR FEDF R FDEV+ CF++ P +P F EA TSL
Sbjct: 1252 ASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSL 1311
Query: 1407 YSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNILVDYGLRRITFLIA 1466
Y ED K R+EPIHILNV+I+ +ED+ L + R F Q K LVD+G+RR+TFL+A
Sbjct: 1312 YDED--KVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVA 1369
Query: 1467 QE---------------KEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLT 1511
Q+ +EFPKFFTFRARD+F EDRIYRHLEPALAFQLELNRMRNFDLT
Sbjct: 1370 QKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLT 1429
Query: 1512 AVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLE 1571
A+PCANHKMHLYLGAAKV+ G EVTD+RFF+RAIIRHSDL+TKEASFEYLQNEGERLLLE
Sbjct: 1430 AIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLE 1489
Query: 1572 AMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAE 1631
AMDELEVAFNNT+VRTDCNHIFLNFVPTVIMDP KIEESVR MVMRYGSRLWKLRVLQAE
Sbjct: 1490 AMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAE 1549
Query: 1632 VKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGML 1691
+KINIR T TG A+PIRLF+TNESGYYLDISLYKEVTDSR+ IMF ++G+KQGP HGML
Sbjct: 1550 LKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGML 1609
Query: 1692 INTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGS--------PDKYPKDIL 1743
INTPYVTKDLLQ+KRFQAQ+LGTTYIYD PEMFRQ+L KLW S P D+L
Sbjct: 1610 INTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDML 1669
Query: 1744 TYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFG 1803
TYTELVLD QGQLV MNRLPGGNE+GMVA+KM FK+ EYPEGRD+IVIGNDIT+RIGSFG
Sbjct: 1670 TYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFG 1729
Query: 1804 PGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLY 1863
P EDLL+LRASE+ARAEGIP+IYV+ANSGARIG+AEEI+HMFHVAWVDPEDP+KG++YLY
Sbjct: 1730 PQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLY 1789
Query: 1864 LTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYE 1923
LTPQDY R+S+LNSVHC+H+E+ GESRY ITDIIGK++G+G ENLRGSGMIAGESSLAY
Sbjct: 1790 LTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYN 1849
Query: 1924 EIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGV 1983
EI+TISLVTCRAIGIGAYLVRLGQR IQVENSH+ILTGA ALNKVLGREVYTSNNQLGG+
Sbjct: 1850 EIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGI 1909
Query: 1984 QIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPY 2043
QIMH NGV+H TV DDFEGV+T+L WLSYMPK HS VP++ DPIDR IEF+P++ PY
Sbjct: 1910 QIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKTPY 1969
Query: 2044 DPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRT 2103
DPRWMLAGRPHPT KG W SGFFD+GSF EIM PWAQTVV GRARLGGIPVGV+AVETRT
Sbjct: 1970 DPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRT 2029
Query: 2104 VEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGG 2163
VE+++PADPANLDSEAKIIQQAGQVWFPDSA+KT QA+KDFNRE LPLM+FANWRGFSGG
Sbjct: 2030 VELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGG 2089
Query: 2164 MKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKE 2223
MKDMYDQVLKFGAYIVDGLR+ QP+L+YIPP AELRGGSWVVID++INP +EMYAD+E
Sbjct: 2090 MKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRE 2149
Query: 2224 SRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKARE 2283
SRG VLEPEGTVEIKFR+KDL+K+MRR+DP Y L E+LG P+LS +RK+LE +LK RE
Sbjct: 2150 SRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAERKELENKLKERE 2209
Query: 2284 DLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEI 2343
+ L+PIYHQVAVQFAD HDTPGRM EKGVISDIL+WKT+RTF YWRLRRLLLED VK++I
Sbjct: 2210 EFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKI 2269
Query: 2344 LQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENI 2403
A+ EL+ IQ+MLRRWFVE EG VKAY+WDNN+ + +WLE+ DG S I ENI
Sbjct: 2270 HNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENI 2329
Query: 2404 TYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAS 2457
+ D VLK IR LV+ NPEVA+D +I+++QHISP +RA+V+ +LSTMDSP++
Sbjct: 2330 KCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST 2383
>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
sapiens]
Length = 2288
Score = 3533 bits (9162), Expect = 0.0
Identities = 1736/2274 (76%), Positives = 1983/2274 (87%), Gaps = 37/2274 (1%)
Query: 218 RPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMR 277
R SMSGLHLVK+GR+ KK+D RDFTVASPAEFVTRFGG++VIEKVLIANNGIAAVKCMR
Sbjct: 18 RSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMR 77
Query: 278 SIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVD 337
SIRRW+YEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELI+D
Sbjct: 78 SIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILD 137
Query: 338 IAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQV 397
IAKRIPVQAVWAGWGHASENPKLPELL KNG+AF+GPPS+AMWALGDKIAS++VAQT +
Sbjct: 138 IAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGI 197
Query: 398 PTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASE 457
PTLPWSGSGL V+W E+D + + ++VP+++Y+KG VKDVD+GL+AAE +G+P+MIKASE
Sbjct: 198 PTLPWSGSGLRVDWQENDFSK-RILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASE 256
Query: 458 GGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLF 517
GGGGKGIRK +A+DFP LFRQVQ+E+PGSPIF+M+LA+ +RHLEVQILADQYGNA+SLF
Sbjct: 257 GGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLF 316
Query: 518 GRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFH 577
GRDCS+QRRHQKI+EEAPATIA A+FE MEQCA++LAK VGYVSAGTVEYLYSQDGSF+
Sbjct: 317 GRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFY 376
Query: 578 FLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFET 637
FLELNPRLQVEHPCTEM+ADVNLPAAQLQIAMG+PL+R+KDIR++YG SPWG +PI FE
Sbjct: 377 FLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFED 436
Query: 638 PSNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFAD 697
++ P RGHVIAARITSENPDEGFKPSSGTVQELNFRS+KNVWGYFSVAA GGLHEFAD
Sbjct: 437 SAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFAD 496
Query: 698 SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLD 757
SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLI LLETESFQ N IDTGWLD
Sbjct: 497 SQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLD 556
Query: 758 YLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVEL 817
LIAEKVQAE+PD MLGVVCGAL+VAD R +++FLHSLERGQVLPA +LLN VDVEL
Sbjct: 557 RLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVEL 616
Query: 818 IYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSY 877
IY GVKY+LKV RQS +V+IMNG +E+D HRL+DGGLLLSY+G+SYTTYMKEEVD Y
Sbjct: 617 IYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRY 676
Query: 878 RITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQ 937
RITIGNKTCVFEKENDP+V+RSPSAGKL QY VEDGGHV AG YAE+EVMKM+MTL
Sbjct: 677 RITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAV 736
Query: 938 ERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFH 997
E G + Y+KRPGA L+ GCV+A+++LD+PSKV AE TG LP Q+ + GEKLH+VFH
Sbjct: 737 ESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFH 796
Query: 998 SVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPV 1057
VL+NL NVM+G+CLP+P FS K+K+WV++LM TLR PSLPLLELQ+IMTSV+GRIP V
Sbjct: 797 YVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNV 856
Query: 1058 EKSVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFINTQSIVQLVQR 1117
EKS+++ MAQYASNITSVLCQFPSQQIA ILD HAATL RK++REVFF+NTQSIVQLVQR
Sbjct: 857 EKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQR 916
Query: 1118 YRSGIRGYMKTVVLDLLRRYLRVEHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQV 1177
YRSGIRG+MK VV+DLLR+YLRVE FQ HYDKCV LRE+ K DM+ VL+ IFSHAQV
Sbjct: 917 YRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQV 976
Query: 1178 AKKNQLVIMLIDELCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYE 1237
KKN LV MLID+LCG DP+L+DEL++IL ELTQLSK+ + KVALRARQ+LIASHLPSYE
Sbjct: 977 TKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYE 1036
Query: 1238 LRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYV 1297
LRHNQVESIFLSAIDMYGHQFC ENL+KLILSET+IFDVLP FFYH+N+VV MA+LEVYV
Sbjct: 1037 LRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYV 1096
Query: 1298 RRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMTVPI--SITNPDLLRH------ 1349
RR YIAYELNS+QHRQL D TCVVEFQFMLP+SHPNR +P ++ L H
Sbjct: 1097 RRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHV 1156
Query: 1350 --STELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEA-RTSL 1406
+++ +D+ F+P CQRMG MV+FR FEDF R FDEV+ CF++ P +P F EA TSL
Sbjct: 1157 ASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSL 1216
Query: 1407 YSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNILVDYGLRRITFLIA 1466
Y ED K R+EPIHILNV+I+ +ED+ L + R F Q K LVD+G+RR+TFL+A
Sbjct: 1217 YDED--KVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVA 1274
Query: 1467 QE---------------KEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLT 1511
Q+ +EFPKFFTFRARD+F EDRIYRHLEPALAFQLELNRMRNFDLT
Sbjct: 1275 QKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLT 1334
Query: 1512 AVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLE 1571
A+PCANHKMHLYLGAAKV+ G EVTD+RFF+RAIIRHSDL+TKEASFEYLQNEGERLLLE
Sbjct: 1335 AIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLE 1394
Query: 1572 AMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAE 1631
AMDELEVAFNNT+VRTDCNHIFLNFVPTVIMDP KIEESVR MVMRYGSRLWKLRVLQAE
Sbjct: 1395 AMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAE 1454
Query: 1632 VKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGML 1691
+KINIR T TG A+PIRLF+TNESGYYLDISLYKEVTDSR+ IMF ++G+KQGP HGML
Sbjct: 1455 LKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGML 1514
Query: 1692 INTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGS--------PDKYPKDIL 1743
INTPYVTKDLLQ+KRFQAQ+LGTTYIYD PEMFRQ+L KLW S P D+L
Sbjct: 1515 INTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDML 1574
Query: 1744 TYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFG 1803
TYTELVLD QGQLV MNRLPGGNE+GMVA+KM FK+ EYPEGRD+IVIGNDIT+RIGSFG
Sbjct: 1575 TYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFG 1634
Query: 1804 PGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLY 1863
P EDLL+LRASE+ARAEGIP+IYV+ANSGARIG+AEEI+HMFHVAWVDPEDP+KG++YLY
Sbjct: 1635 PQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLY 1694
Query: 1864 LTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYE 1923
LTPQDY R+S+LNSVHC+H+E+ GESRY ITDIIGK++G+G ENLRGSGMIAGESSLAY
Sbjct: 1695 LTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYN 1754
Query: 1924 EIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGV 1983
EI+TISLVTCRAIGIGAYLVRLGQR IQVENSH+ILTGA ALNKVLGREVYTSNNQLGG+
Sbjct: 1755 EIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGI 1814
Query: 1984 QIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPY 2043
QIMH NGV+H TV DDFEGV+T+L WLSYMPK HS VP++ DPIDR IEF+P++ PY
Sbjct: 1815 QIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKTPY 1874
Query: 2044 DPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRT 2103
DPRWMLAGRPHPT KG W SGFFD+GSF EIM PWAQTVV GRARLGGIPVGV+AVETRT
Sbjct: 1875 DPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRT 1934
Query: 2104 VEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGG 2163
VE+++PADPANLDSEAKIIQQAGQVWFPDSA+KT QA+KDFNRE LPLM+FANWRGFSGG
Sbjct: 1935 VELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGG 1994
Query: 2164 MKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKE 2223
MKDMYDQVLKFGAYIVDGLR+ QP+L+YIPP AELRGGSWVVID++INP +EMYAD+E
Sbjct: 1995 MKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRE 2054
Query: 2224 SRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKARE 2283
SRG VLEPEGTVEIKFR+KDL+K+MRR+DP Y L E+LG P+LS +RK+LE +LK RE
Sbjct: 2055 SRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAERKELENKLKERE 2114
Query: 2284 DLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEI 2343
+ L+PIYHQVAVQFAD HDTPGRM EKGVISDIL+WKT+RTF YWRLRRLLLED VK++I
Sbjct: 2115 EFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKI 2174
Query: 2344 LQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENI 2403
A+ EL+ IQ+MLRRWFVE EG VKAY+WDNN+ + +WLE+ DG S I ENI
Sbjct: 2175 HNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENI 2234
Query: 2404 TYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAS 2457
+ D VLK IR LV+ NPEVA+D +I+++QHISP +RA+V+ +LSTMDSP++
Sbjct: 2235 KCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST 2288
>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
sapiens]
Length = 2268
Score = 3530 bits (9154), Expect = 0.0
Identities = 1734/2271 (76%), Positives = 1981/2271 (87%), Gaps = 37/2271 (1%)
Query: 221 MSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIR 280
MSGLHLVK+GR+ KK+D RDFTVASPAEFVTRFGG++VIEKVLIANNGIAAVKCMRSIR
Sbjct: 1 MSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIR 60
Query: 281 RWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAK 340
RW+YEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELI+DIAK
Sbjct: 61 RWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAK 120
Query: 341 RIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTL 400
RIPVQAVWAGWGHASENPKLPELL KNG+AF+GPPS+AMWALGDKIAS++VAQT +PTL
Sbjct: 121 RIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTL 180
Query: 401 PWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGG 460
PWSGSGL V+W E+D + + ++VP+++Y+KG VKDVD+GL+AAE +G+P+MIKASEGGG
Sbjct: 181 PWSGSGLRVDWQENDFSK-RILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGG 239
Query: 461 GKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRD 520
GKGIRK +A+DFP LFRQVQ+E+PGSPIF+M+LA+ +RHLEVQILADQYGNA+SLFGRD
Sbjct: 240 GKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRD 299
Query: 521 CSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLE 580
CS+QRRHQKI+EEAPATIA A+FE MEQCA++LAK VGYVSAGTVEYLYSQDGSF+FLE
Sbjct: 300 CSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLE 359
Query: 581 LNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSN 640
LNPRLQVEHPCTEM+ADVNLPAAQLQIAMG+PL+R+KDIR++YG SPWG +PI FE ++
Sbjct: 360 LNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFEDSAH 419
Query: 641 PPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQF 700
P RGHVIAARITSENPDEGFKPSSGTVQELNFRS+KNVWGYFSVAA GGLHEFADSQF
Sbjct: 420 VPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQF 479
Query: 701 GHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLI 760
GHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLI LLETESFQ N IDTGWLD LI
Sbjct: 480 GHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLI 539
Query: 761 AEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYG 820
AEKVQAE+PD MLGVVCGAL+VAD R +++FLHSLERGQVLPA +LLN VDVELIY
Sbjct: 540 AEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYE 599
Query: 821 GVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRIT 880
GVKY+LKV RQS +V+IMNG +E+D HRL+DGGLLLSY+G+SYTTYMKEEVD YRIT
Sbjct: 600 GVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRIT 659
Query: 881 IGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERG 940
IGNKTCVFEKENDP+V+RSPSAGKL QY VEDGGHV AG YAE+EVMKM+MTL E G
Sbjct: 660 IGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESG 719
Query: 941 RVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVL 1000
+ Y+KRPGA L+ GCV+A+++LD+PSKV AE TG LP Q+ + GEKLH+VFH VL
Sbjct: 720 CIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVL 779
Query: 1001 ENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKS 1060
+NL NVM+G+CLP+P FS K+K+WV++LM TLR PSLPLLELQ+IMTSV+GRIP VEKS
Sbjct: 780 DNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKS 839
Query: 1061 VRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRS 1120
+++ MAQYASNITSVLCQFPSQQIA ILD HAATL RK++REVFF+NTQSIVQLVQRYRS
Sbjct: 840 IKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRS 899
Query: 1121 GIRGYMKTVVLDLLRRYLRVEHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKK 1180
GIRG+MK VV+DLLR+YLRVE FQ HYDKCV LRE+ K DM+ VL+ IFSHAQV KK
Sbjct: 900 GIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKK 959
Query: 1181 NQLVIMLIDELCGPDPSLSDELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRH 1240
N LV MLID+LCG DP+L+DEL++IL ELTQLSK+ + KVALRARQ+LIASHLPSYELRH
Sbjct: 960 NLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRH 1019
Query: 1241 NQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRG 1300
NQVESIFLSAIDMYGHQFC ENL+KLILSET+IFDVLP FFYH+N+VV MA+LEVYVRR
Sbjct: 1020 NQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRA 1079
Query: 1301 YIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMTVPI--SITNPDLLRH--------S 1350
YIAYELNS+QHRQL D TCVVEFQFMLP+SHPNR +P ++ L H
Sbjct: 1080 YIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASV 1139
Query: 1351 TELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPKDTPLFSEA-RTSLYSE 1409
+++ +D+ F+P CQRMG MV+FR FEDF R FDEV+ CF++ P +P F EA TSLY E
Sbjct: 1140 SDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSLYDE 1199
Query: 1410 DDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNILVDYGLRRITFLIAQE- 1468
D K R+EPIHILNV+I+ +ED+ L + R F Q K LVD+G+RR+TFL+AQ+
Sbjct: 1200 D--KVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVAQKD 1257
Query: 1469 --------------KEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRNFDLTAVP 1514
+EFPKFFTFRARD+F EDRIYRHLEPALAFQLELNRMRNFDLTA+P
Sbjct: 1258 FRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIP 1317
Query: 1515 CANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGERLLLEAMD 1574
CANHKMHLYLGAAKV+ G EVTD+RFF+RAIIRHSDL+TKEASFEYLQNEGERLLLEAMD
Sbjct: 1318 CANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMD 1377
Query: 1575 ELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRVLQAEVKI 1634
ELEVAFNNT+VRTDCNHIFLNFVPTVIMDP KIEESVR MVMRYGSRLWKLRVLQAE+KI
Sbjct: 1378 ELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKI 1437
Query: 1635 NIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQHGMLINT 1694
NIR T TG A+PIRLF+TNESGYYLDISLYKEVTDSR+ IMF ++G+KQGP HGMLINT
Sbjct: 1438 NIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINT 1497
Query: 1695 PYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGS--------PDKYPKDILTYT 1746
PYVTKDLLQ+KRFQAQ+LGTTYIYD PEMFRQ+L KLW S P D+LTYT
Sbjct: 1498 PYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYT 1557
Query: 1747 ELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGE 1806
ELVLD QGQLV MNRLPGGNE+GMVA+KM FK+ EYPEGRD+IVIGNDIT+RIGSFGP E
Sbjct: 1558 ELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFGPQE 1617
Query: 1807 DLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTP 1866
DLL+LRASE+ARAEGIP+IYV+ANSGARIG+AEEI+HMFHVAWVDPEDP+KG++YLYLTP
Sbjct: 1618 DLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLYLTP 1677
Query: 1867 QDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIV 1926
QDY R+S+LNSVHC+H+E+ GESRY ITDIIGK++G+G ENLRGSGMIAGESSLAY EI+
Sbjct: 1678 QDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYNEII 1737
Query: 1927 TISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIM 1986
TISLVTCRAIGIGAYLVRLGQR IQVENSH+ILTGA ALNKVLGREVYTSNNQLGG+QIM
Sbjct: 1738 TISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIM 1797
Query: 1987 HYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPYDPR 2046
H NGV+H TV DDFEGV+T+L WLSYMPK HS VP++ DPIDR IEF+P++ PYDPR
Sbjct: 1798 HNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKTPYDPR 1857
Query: 2047 WMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEV 2106
WMLAGRPHPT KG W SGFFD+GSF EIM PWAQTVV GRARLGGIPVGV+AVETRTVE+
Sbjct: 1858 WMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVEL 1917
Query: 2107 AVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGGMKD 2166
++PADPANLDSEAKIIQQAGQVWFPDSA+KT QA+KDFNRE LPLM+FANWRGFSGGMKD
Sbjct: 1918 SIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKD 1977
Query: 2167 MYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRG 2226
MYDQVLKFGAYIVDGLR+ QP+L+YIPP AELRGGSWVVID++INP +EMYAD+ESRG
Sbjct: 1978 MYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRESRG 2037
Query: 2227 GVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKAREDLL 2286
VLEPEGTVEIKFR+KDL+K+MRR+DP Y L E+LG P+LS +RK+LE +LK RE+ L
Sbjct: 2038 SVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAERKELENKLKEREEFL 2097
Query: 2287 LPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQA 2346
+PIYHQVAVQFAD HDTPGRM EKGVISDIL+WKT+RTF YWRLRRLLLED VK++I A
Sbjct: 2098 IPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNA 2157
Query: 2347 SGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYL 2406
+ EL+ IQ+MLRRWFVE EG VKAY+WDNN+ + +WLE+ DG S I ENI +
Sbjct: 2158 NPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENIKCI 2217
Query: 2407 KHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAS 2457
D VLK IR LV+ NPEVA+D +I+++QHISP +RA+V+ +LSTMDSP++
Sbjct: 2218 SRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILSTMDSPST 2268
>gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide
isoform a precursor [Homo sapiens]
Length = 728
Score = 246 bits (627), Expect = 3e-64
Identities = 207/744 (27%), Positives = 342/744 (45%), Gaps = 113/744 (15%)
Query: 257 DRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADH 316
++ +K+L+AN G A + +R+ ++ + + D+ A++ ++KMAD
Sbjct: 60 EKTFDKILVANRGEIACRVIRTCKKMGIK-----------TVAIHSDVDASSVHVKMADE 108
Query: 317 YVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPS 376
V V P + +Y N++ I++ K+ QAV G+G SEN + L V F+GP +
Sbjct: 109 AVCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDT 168
Query: 377 EAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKD 436
A+ A+GDKI S ++A+ +V T+P +D G VKD
Sbjct: 169 HAIQAMGDKIESKLLAKKAEVNTIPG--------------------------FD-GVVKD 201
Query: 437 VDEGLEAAERIGFPLMIKASEGGGGKGIRKA----ESAEDFPILFRQVQSEIPGSPIFLM 492
+E + A IG+P+MIKAS GGGGKG+R A E+ + F + ++ S + +
Sbjct: 202 AEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIE 261
Query: 493 KLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAI 552
K + RH+E+Q+L D++GNA+ L R+CSIQRR+QK+VEEAP+ M + A+
Sbjct: 262 KFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAV 321
Query: 553 RLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVP 612
LA+ V Y SAGTVE+L +F+FLE+N RLQVEHP TE I ++L +++A G P
Sbjct: 322 ALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYP 381
Query: 613 L-HRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGF-KPSSGTVQ 670
L H+ DIR+ G + R+ +E+P + F PS G +
Sbjct: 382 LRHKQADIRI-----------------------NGWAVECRVYAEDPYKSFGLPSIGRLS 418
Query: 671 ELNFRSSKNVWGY---FSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 727
+ ++ ++ G + + + D ++G +R EA+ M AL IR
Sbjct: 419 Q--YQEPLHLPGVRVDSGIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIR 476
Query: 728 GDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAE------KVQAEKPDIMLGVVCGALN 781
G + L ++ F DI T +L + + ++EK + L
Sbjct: 477 G-VTHNIALLREVIINSRFVKGDISTKFLSDVYPDGFKGHMLTKSEKNQL--------LA 527
Query: 782 VADAMFRTCMTDFLHSLE--RGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLI 839
+A ++F H E R V+ D + V+L K VA + ++F +
Sbjct: 528 IASSLFVAFQLRAQHFQENSRMPVIKPDIANWELSVKL---HDKVHTVVASNNGSVFSVE 584
Query: 840 MNGCHIEI-DAHRLNDGGLLLSYNGNSYTTY-MKEEVDS----------YRITIGNKTC- 886
++G + + L L +S +G T + E Y++ I +
Sbjct: 585 VDGSKLNVTSTWNLASPLLSVSVDGTQRTVQCLSREAGGNMSIQFLGTVYKVNILTRLAA 644
Query: 887 -----VFEK--ENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQER 939
+ EK E+ +VLRSP G + +V+ G V G +E MKM ++ +
Sbjct: 645 ELNKFMLEKVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKT 704
Query: 940 GRVKYIK-RPGAVLEAGCVVARLE 962
G VK + + G + G ++ LE
Sbjct: 705 GTVKSVHCQAGDTVGEGDLLVELE 728
>gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide
isoform b [Homo sapiens]
Length = 702
Score = 245 bits (625), Expect = 4e-64
Identities = 207/743 (27%), Positives = 341/743 (45%), Gaps = 113/743 (15%)
Query: 258 RVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 317
+ +K+L+AN G A + +R+ ++ + + D+ A++ ++KMAD
Sbjct: 35 KTFDKILVANRGEIACRVIRTCKKMGIK-----------TVAIHSDVDASSVHVKMADEA 83
Query: 318 VPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSE 377
V V P + +Y N++ I++ K+ QAV G+G SEN + L V F+GP +
Sbjct: 84 VCVGPAPTSKSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTH 143
Query: 378 AMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDV 437
A+ A+GDKI S ++A+ +V T+P +D G VKD
Sbjct: 144 AIQAMGDKIESKLLAKKAEVNTIPG--------------------------FD-GVVKDA 176
Query: 438 DEGLEAAERIGFPLMIKASEGGGGKGIRKA----ESAEDFPILFRQVQSEIPGSPIFLMK 493
+E + A IG+P+MIKAS GGGGKG+R A E+ + F + ++ S + + K
Sbjct: 177 EEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEETRDGFRLSSQEAASSFGDDRLLIEK 236
Query: 494 LAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIR 553
+ RH+E+Q+L D++GNA+ L R+CSIQRR+QK+VEEAP+ M + A+
Sbjct: 237 FIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQKVVEEAPSIFLDAETRRAMGEQAVA 296
Query: 554 LAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPL 613
LA+ V Y SAGTVE+L +F+FLE+N RLQVEHP TE I ++L +++A G PL
Sbjct: 297 LARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEHPVTECITGLDLVQEMIRVAKGYPL 356
Query: 614 -HRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGF-KPSSGTVQE 671
H+ DIR+ G + R+ +E+P + F PS G + +
Sbjct: 357 RHKQADIRI-----------------------NGWAVECRVYAEDPYKSFGLPSIGRLSQ 393
Query: 672 LNFRSSKNVWGY---FSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRG 728
++ ++ G + + + D ++G +R EA+ M AL IRG
Sbjct: 394 --YQEPLHLPGVRVDSGIQPGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYVIRG 451
Query: 729 DFRTTVEYLINLLETESFQNNDIDTGWLDYLIAE------KVQAEKPDIMLGVVCGALNV 782
+ L ++ F DI T +L + + ++EK + L +
Sbjct: 452 -VTHNIALLREVIINSRFVKGDISTKFLSDVYPDGFKGHMLTKSEKNQL--------LAI 502
Query: 783 ADAMFRTCMTDFLHSLE--RGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM 840
A ++F H E R V+ D + V+L K VA + ++F + +
Sbjct: 503 ASSLFVAFQLRAQHFQENSRMPVIKPDIANWELSVKL---HDKVHTVVASNNGSVFSVEV 559
Query: 841 NGCHIEI-DAHRLNDGGLLLSYNGNSYTTY-MKEEVDS----------YRITIGNKTC-- 886
+G + + L L +S +G T + E Y++ I +
Sbjct: 560 DGSKLNVTSTWNLASPLLSVSVDGTQRTVQCLSREAGGNMSIQFLGTVYKVNILTRLAAE 619
Query: 887 ----VFEK--ENDPTVLRSPSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERG 940
+ EK E+ +VLRSP G + +V+ G V G +E MKM ++ + G
Sbjct: 620 LNKFMLEKVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTG 679
Query: 941 RVKYIK-RPGAVLEAGCVVARLE 962
VK + + G + G ++ LE
Sbjct: 680 TVKSVHCQAGDTVGEGDLLVELE 702
>gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
precursor [Homo sapiens]
Length = 725
Score = 235 bits (600), Expect = 4e-61
Identities = 211/749 (28%), Positives = 325/749 (43%), Gaps = 112/749 (14%)
Query: 258 RVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 317
R I KVLIAN G A + MR+ ++ ++ V + + D N+ ++ MAD
Sbjct: 47 RNITKVLIANRGEIACRVMRTAKKLG---------VQTVAVYSEAD--RNSMHVDMADEA 95
Query: 318 VPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSE 377
+ P+ +Y ++E I+ +AK QA+ G G SEN + EL + G+ F+GPP
Sbjct: 96 YSIGPAPSQQSYLSMEKIIQVAKTSAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPS 155
Query: 378 AMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDV 437
A+ +G K S + VP + ED D+ C+K
Sbjct: 156 AIRDMGIKSTSKSIMAAAGVPVVEGYHG--------------------EDQSDQ-CLK-- 192
Query: 438 DEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGS----PIFLMK 493
E A RIG+P+MIKA GGGGKG+R S ++F + E S + + K
Sbjct: 193 ----EHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQLESARREAKKSFNDDAMLIEK 248
Query: 494 LAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIR 553
RH+EVQ+ D +GNAV LF RDCS+QRRHQKI+EEAPA + + + + A+R
Sbjct: 249 FVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIEEAPAPGIKSEVRKKLGEAAVR 308
Query: 554 LAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPL 613
AK V YV AGTVE++ +F F+E+N RLQVEHP TEMI +L QL+IA G +
Sbjct: 309 AAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVTEMITGTDLVEWQLRIAAGEKI 368
Query: 614 HRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQELN 673
P+S E + +GH ARI +E+P F P +G + L+
Sbjct: 369 ------------------PLSQEEIT----LQGHAFEARIYAEDPSNNFMPVAGPLVHLS 406
Query: 674 F-RSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRT 732
R+ + V + D W +R+ A++ + +L++ +I G T
Sbjct: 407 TPRADPSTRIETGVRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVG-LHT 465
Query: 733 TVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMT 792
+++L+NL F+ ++ T ++ + + + K + AL + + MT
Sbjct: 466 NIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGL--ILKEKAMT 523
Query: 793 DFLHSLERGQVLPADS----LLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEID 848
D Q P S LN+ LK + ++ + V +
Sbjct: 524 DTFTLQAHDQFSPFSSSSGRRLNISYTR------NMTLKDGKNNVAIAVTYNHD-----G 572
Query: 849 AHRLNDGGLLLSYNGNSYT----TYMKEEVDSYR-----ITIGNKTCVFEKEND------ 893
++ + GN Y+ TY+K V+ I + N +F KE
Sbjct: 573 SYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIYLFSKEGSIEIDIP 632
Query: 894 -PTVLRS------------PSAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERG 940
P L S P G + + V+ G V+AG S M MKM T+ + G
Sbjct: 633 VPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDG 692
Query: 941 RVKYI-KRPGAVLEAGCVVARLELDDPSK 968
VK + R GA + E ++ K
Sbjct: 693 TVKKVFYREGAQANRHTPLVEFEEEESDK 721
>gi|106049528 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 215 bits (548), Expect = 4e-55
Identities = 156/509 (30%), Positives = 241/509 (47%), Gaps = 74/509 (14%)
Query: 260 IEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVP 319
I+KV++AN G A++ R+ E IR V + + +D K + Y+
Sbjct: 37 IKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAYLI 86
Query: 320 VPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAM 379
G Y ++ I+ +AK V AV G+G SE + GV F+GP E +
Sbjct: 87 GRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVV 146
Query: 380 WALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDE 439
+GDK+ + +A VP +P + + +T + E
Sbjct: 147 RKMGDKVEARAIAIAAGVPVVPGTDAPIT---------------------------SLHE 179
Query: 440 GLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSE----IPGSPIFLMKLA 495
E + GFP++ KA+ GGGG+G+R S E+ + + SE +F+ K
Sbjct: 180 AHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFI 239
Query: 496 QHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLA 555
+ RH+EVQIL DQYGN + L+ RDCSIQRRHQK+VE APA + + +++LA
Sbjct: 240 EKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
Query: 556 KTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLH- 614
K VGY +AGTVE+L + G +F+E+N RLQVEH TE I DV+L AQ+ +A G L
Sbjct: 300 KQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPD 359
Query: 615 ---RLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQE 671
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 360 LGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIEV 396
Query: 672 LNFRSSKNVWGYFSVAAT---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRG 728
FRS + + A+ + DS + G++ A + M AL E +RG
Sbjct: 397 --FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRG 454
Query: 729 DFRTTVEYLINLLETESFQNNDIDTGWLD 757
+T + +L N+L + F +DT ++D
Sbjct: 455 -VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
>gi|106049295 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 215 bits (548), Expect = 4e-55
Identities = 156/509 (30%), Positives = 241/509 (47%), Gaps = 74/509 (14%)
Query: 260 IEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVP 319
I+KV++AN G A++ R+ E IR V + + +D K + Y+
Sbjct: 37 IKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAYLI 86
Query: 320 VPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAM 379
G Y ++ I+ +AK V AV G+G SE + GV F+GP E +
Sbjct: 87 GRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVV 146
Query: 380 WALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDE 439
+GDK+ + +A VP +P + + +T + E
Sbjct: 147 RKMGDKVEARAIAIAAGVPVVPGTDAPIT---------------------------SLHE 179
Query: 440 GLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSE----IPGSPIFLMKLA 495
E + GFP++ KA+ GGGG+G+R S E+ + + SE +F+ K
Sbjct: 180 AHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFI 239
Query: 496 QHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLA 555
+ RH+EVQIL DQYGN + L+ RDCSIQRRHQK+VE APA + + +++LA
Sbjct: 240 EKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
Query: 556 KTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLH- 614
K VGY +AGTVE+L + G +F+E+N RLQVEH TE I DV+L AQ+ +A G L
Sbjct: 300 KQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPD 359
Query: 615 ---RLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQE 671
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 360 LGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIEV 396
Query: 672 LNFRSSKNVWGYFSVAAT---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRG 728
FRS + + A+ + DS + G++ A + M AL E +RG
Sbjct: 397 --FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRG 454
Query: 729 DFRTTVEYLINLLETESFQNNDIDTGWLD 757
+T + +L N+L + F +DT ++D
Sbjct: 455 -VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
>gi|106049292 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 215 bits (548), Expect = 4e-55
Identities = 156/509 (30%), Positives = 241/509 (47%), Gaps = 74/509 (14%)
Query: 260 IEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVP 319
I+KV++AN G A++ R+ E IR V + + +D K + Y+
Sbjct: 37 IKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAYLI 86
Query: 320 VPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAM 379
G Y ++ I+ +AK V AV G+G SE + GV F+GP E +
Sbjct: 87 GRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVV 146
Query: 380 WALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDE 439
+GDK+ + +A VP +P + + +T + E
Sbjct: 147 RKMGDKVEARAIAIAAGVPVVPGTDAPIT---------------------------SLHE 179
Query: 440 GLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSE----IPGSPIFLMKLA 495
E + GFP++ KA+ GGGG+G+R S E+ + + SE +F+ K
Sbjct: 180 AHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFI 239
Query: 496 QHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLA 555
+ RH+EVQIL DQYGN + L+ RDCSIQRRHQK+VE APA + + +++LA
Sbjct: 240 EKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
Query: 556 KTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLH- 614
K VGY +AGTVE+L + G +F+E+N RLQVEH TE I DV+L AQ+ +A G L
Sbjct: 300 KQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPD 359
Query: 615 ---RLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQE 671
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 360 LGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIEV 396
Query: 672 LNFRSSKNVWGYFSVAAT---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRG 728
FRS + + A+ + DS + G++ A + M AL E +RG
Sbjct: 397 --FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRG 454
Query: 729 DFRTTVEYLINLLETESFQNNDIDTGWLD 757
+T + +L N+L + F +DT ++D
Sbjct: 455 -VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
>gi|119943100 propionyl Coenzyme A carboxylase, beta polypeptide [Homo
sapiens]
Length = 539
Score = 79.3 bits (194), Expect = 4e-14
Identities = 94/419 (22%), Positives = 174/419 (41%), Gaps = 55/419 (13%)
Query: 1860 KYLYLTPQDYTRIS-SLNSVHCKHIEEGGESRYMI-TDIIGKDDG------LGVENLRGS 1911
+ +Y+ QD+T SL+ H + I + + + +IG +D GVE+L G
Sbjct: 117 RLVYVFSQDFTVFGGSLSGAHAQKICKIMDQAITVGAPVIGLNDSGGARIQEGVESLAGY 176
Query: 1912 GMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVEN-SHIILTGASALNKVLG 1970
I + A I ISL+ G Y L V++ S++ +TG + V
Sbjct: 177 ADIFLRNVTASGVIPQISLIMGPCAGGAVYSPALTDFTFMVKDTSYLFITGPDVVKSVTN 236
Query: 1971 REVYTSNNQLGGVQI-MHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDP 2029
+V + +LGG + +GV+H +D + + + ++ +Y+P + P P+ DP
Sbjct: 237 EDV--TQEELGGAKTHTTMSGVAHRAFENDVDALCNLRDFFNYLPLSSQDPAPVRECHDP 294
Query: 2030 IDREIEFLPSRAPYD--PRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRA 2087
DR + L + P + + + H + D F EIM +A+ ++ G A
Sbjct: 295 SDRLVPELDTIVPLESTKAYNMVDIIHSVV---------DEREFFEIMPNYAKNIIVGFA 345
Query: 2088 RLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNRE 2147
R+ G VG++ + + + +S+ K A+ V+ +
Sbjct: 346 RMNGRTVGIVGNQPKVASGCLDI---------------------NSSVKGARFVRFCDAF 384
Query: 2148 KLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVI 2207
+PL+ F + GF G Y +++ GA ++ + P + I A GG++ V+
Sbjct: 385 NIPLITFVDVPGFLPGTAQEYGGIIRHGAKLLYAFAEATVPKVTVITRKA--YGGAYDVM 442
Query: 2208 DATINPLCIEM-YADKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEP 2265
+ LC + YA + V+ +G VEI F K ++ A + +E+ P
Sbjct: 443 SS--KHLCGDTNYAWPTAEIAVMGAKGAVEIIF------KGHENVEAAQAEYIEKFANP 493
>gi|18105007 carbamoylphosphate synthetase 2/aspartate
transcarbamylase/dihydroorotase [Homo sapiens]
Length = 2225
Score = 66.2 bits (160), Expect = 4e-10
Identities = 50/219 (22%), Positives = 102/219 (46%), Gaps = 14/219 (6%)
Query: 408 TVEWTEDDLQQGKRIS-VPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRK 466
T+E TED R++ + E V +++ AAER+G+P++++A+ GG G
Sbjct: 508 TIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGF 567
Query: 467 AESAEDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQR- 525
A + E+ L + S + + K + + +E +++ D YGN V++ C+++
Sbjct: 568 ASNREELSALVAPAFAHT--SQVLVDKSLKGWKEIEYEVVRDAYGNCVTV----CNMENL 621
Query: 526 -----RHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEY-LYSQDGSFHFL 579
+ + AP+ ++ + Q AI++ + +G V V+Y L + ++ +
Sbjct: 622 DPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYII 681
Query: 580 ELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKD 618
E+N RL L ++A+G+PL L++
Sbjct: 682 EVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN 720
>gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo
sapiens]
Length = 1049
Score = 53.9 bits (128), Expect = 2e-06
Identities = 47/216 (21%), Positives = 97/216 (44%), Gaps = 14/216 (6%)
Query: 412 TED-DLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESA 470
TED L K + E + V+ +++ L+AA+ IG+P+MI+++ GG G +
Sbjct: 93 TEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNR 152
Query: 471 EDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQR----- 525
E ++ ++ + I + K + +E +++ D N V++ C+++
Sbjct: 153 E--TLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTV----CNMENVDAMG 206
Query: 526 -RHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEY-LYSQDGSFHFLELNP 583
V APA A F+ + + +I + + +G V +++ L+ + +E+N
Sbjct: 207 VHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNA 266
Query: 584 RLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDI 619
RL L +IA+G+PL +K++
Sbjct: 267 RLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNV 302
>gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precursor
[Homo sapiens]
Length = 1506
Score = 53.9 bits (128), Expect = 2e-06
Identities = 47/216 (21%), Positives = 97/216 (44%), Gaps = 14/216 (6%)
Query: 412 TED-DLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESA 470
TED L K + E + V+ +++ L+AA+ IG+P+MI+++ GG G +
Sbjct: 550 TEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNR 609
Query: 471 EDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQR----- 525
E ++ ++ + I + K + +E +++ D N V++ C+++
Sbjct: 610 E--TLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTV----CNMENVDAMG 663
Query: 526 -RHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEY-LYSQDGSFHFLELNP 583
V APA A F+ + + +I + + +G V +++ L+ + +E+N
Sbjct: 664 VHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNA 723
Query: 584 RLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDI 619
RL L +IA+G+PL +K++
Sbjct: 724 RLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNV 759
>gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor
[Homo sapiens]
Length = 1500
Score = 53.9 bits (128), Expect = 2e-06
Identities = 47/216 (21%), Positives = 97/216 (44%), Gaps = 14/216 (6%)
Query: 412 TED-DLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESA 470
TED L K + E + V+ +++ L+AA+ IG+P+MI+++ GG G +
Sbjct: 544 TEDRQLFSDKLNEINEKIAPSFAVESIEDALKAADTIGYPVMIRSAYALGGLGSGICPNR 603
Query: 471 EDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQR----- 525
E ++ ++ + I + K + +E +++ D N V++ C+++
Sbjct: 604 E--TLMDLSTKAFAMTNQILVEKSVTGWKEIEYEVVRDADDNCVTV----CNMENVDAMG 657
Query: 526 -RHQKIVEEAPATIAPLAIFEFMEQCAIRLAKTVGYVSAGTVEY-LYSQDGSFHFLELNP 583
V APA A F+ + + +I + + +G V +++ L+ + +E+N
Sbjct: 658 VHTGDSVVVAPAQTLSNAEFQMLRRTSINVVRHLGIVGECNIQFALHPTSMEYCIIEVNA 717
Query: 584 RLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDI 619
RL L +IA+G+PL +K++
Sbjct: 718 RLSRSSALASKATGYPLAFIAAKIALGIPLPEIKNV 753
>gi|11545863 methylcrotonoyl-Coenzyme A carboxylase 2 (beta) [Homo
sapiens]
Length = 563
Score = 47.8 bits (112), Expect = 1e-04
Identities = 79/337 (23%), Positives = 125/337 (37%), Gaps = 65/337 (19%)
Query: 1857 KGFKYLYLTPQDYTR---ISSLNSVHCKH-IEEGGESRYMITDIIGKDDGLGVENLRGSG 1912
KG Y +T + R I+ N + C + ++ GG D+ D G
Sbjct: 141 KGGAYYPVTVKKQLRAQEIAMQNRLPCIYLVDSGGAYLPRQADVFPDRDHFG-------R 193
Query: 1913 MIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLG-QRVIQVENSHIILTGASALNKVLGR 1971
++ ++ + I I++V GAY+ + + +I + I L G + G
Sbjct: 194 TFYNQAIMSSKNIAQIAVVMGSCTAGGAYVPAMADENIIVRKQGTIFLAGPPLVKAATGE 253
Query: 1972 EVYTSNNQLGGVQI-MHYNGVSHITVPDDFEGVYT---ILEWLSYMPKDNHSPVPIITPT 2027
EV S LGG + +GVS DD ++ ++ L+Y K
Sbjct: 254 EV--SAEDLGGADLHCRKSGVSDHWALDDHHALHLTRKVVRNLNYQKK------------ 299
Query: 2028 DPIDREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQ-----SGFFDHGSFKEIMAPWAQTV 2082
+D IE PS P P L G LK ++ + D F E A + T+
Sbjct: 300 --LDVTIE--PSEEPLFPADELYGIVGANLKRSFDVREVIARIVDGSRFTEFKAFYGDTL 355
Query: 2083 VTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVK 2142
VTG AR+ G PVG++ V F +SA K V+
Sbjct: 356 VTGFARIFGYPVGIVG--------------------------NNGVLFSESAKKGTHFVQ 389
Query: 2143 DFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIV 2179
+ +PL+ N GF G + + + K GA +V
Sbjct: 390 LCCQRNIPLLFLQNITGFMVGREYEAEGIAKDGAKMV 426
Score = 33.5 bits (75), Expect = 2.6
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 9/79 (11%)
Query: 1755 QLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGEDLLYLRAS 1814
QL + +PGG + + G + ++I ND T + G++ P LRA
Sbjct: 107 QLYDNEEVPGGGIITGIG---------RVSGVECMIIANDATVKGGAYYPVTVKKQLRAQ 157
Query: 1815 EMARAEGIPKIYVAANSGA 1833
E+A +P IY+ + GA
Sbjct: 158 EIAMQNRLPCIYLVDSGGA 176
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 9/140 (6%)
Query: 25 KMTDSKPITKS-KSEANLIPSQEPFPASDNSGETPQRNGEGHTLPKTPSQA-----EPAS 78
K+ + + TK+ +S + S + S+ GE PQ HTL TPS+ E A+
Sbjct: 1129 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAA 1188
Query: 79 HKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSAR 138
D SL + P P +S + +P+L ++ + + L A D A+
Sbjct: 1189 ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1248
Query: 139 PQGQQAG--SPSKEDKKQAN 156
PQ Q AG SP K+ A+
Sbjct: 1249 PQ-QAAGMLSPKTGGKEAAS 1267
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 9/140 (6%)
Query: 25 KMTDSKPITKS-KSEANLIPSQEPFPASDNSGETPQRNGEGHTLPKTPSQA-----EPAS 78
K+ + + TK+ +S + S + S+ GE PQ HTL TPS+ E A+
Sbjct: 1052 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAA 1111
Query: 79 HKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSAR 138
D SL + P P +S + +P+L ++ + + L A D A+
Sbjct: 1112 ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1171
Query: 139 PQGQQAG--SPSKEDKKQAN 156
PQ Q AG SP K+ A+
Sbjct: 1172 PQ-QAAGMLSPKTGGKEAAS 1190
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 9/140 (6%)
Query: 25 KMTDSKPITKS-KSEANLIPSQEPFPASDNSGETPQRNGEGHTLPKTPSQA-----EPAS 78
K+ + + TK+ +S + S + S+ GE PQ HTL TPS+ E A+
Sbjct: 1091 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAA 1150
Query: 79 HKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSAR 138
D SL + P P +S + +P+L ++ + + L A D A+
Sbjct: 1151 ESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1210
Query: 139 PQGQQAG--SPSKEDKKQAN 156
PQ Q AG SP K+ A+
Sbjct: 1211 PQ-QAAGMLSPKTGGKEAAS 1229
>gi|19924103 synapsin II isoform IIa [Homo sapiens]
Length = 582
Score = 42.0 bits (97), Expect = 0.007
Identities = 49/178 (27%), Positives = 78/178 (43%), Gaps = 29/178 (16%)
Query: 26 MTDSKPITKSKSEANLIPSQEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDA 85
++ +P+T + ++ + ++P D+S PQR P Q P +G +
Sbjct: 424 LSPQRPLTTQQPQSGTL--KDP----DSSKTPPQR---------PPPQGGPGQPQGMQPP 468
Query: 86 GR----RRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQG 141
G+ RR LPP PP + SSS ++ +P+ + G T G + ++ L+ + P
Sbjct: 469 GKVLPPRR--LPPGPSLPPSSSSSSSSSSSAPQ-RPGGPTTHGDAPSSSSSLAEAQPPL- 524
Query: 142 QQAGSPSKEDKKQANIKRQLMTN---FILGSFDDYSSDEDSVAGSSRESTRKGSRASL 196
A P K K Q +TN F SF S++ED + S RK S ASL
Sbjct: 525 --AAPPQKPQPHPQLNKSQSLTNAFSFSESSFFRSSANEDEAKAETIRSLRK-SFASL 579
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 42.0 bits (97), Expect = 0.007
Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 33 TKSKSEANLIPSQEPFPASDNSGETPQRNGEGHTLPKTPSQA---EPASHKGPKDAGRRR 89
+ S S ++ S +S +S + + EG +LP P A P+ PK+A R
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREG 2593
Query: 90 NSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQAGSPSK 149
P+ K R SSS ++ S ++ + + ++ ++ SSS+ + SP+K
Sbjct: 2594 RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653
Score = 37.4 bits (85), Expect = 0.18
Identities = 34/131 (25%), Positives = 53/131 (40%), Gaps = 14/131 (10%)
Query: 29 SKPITKSKSEANL---IPSQEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDA 85
S P +K+KS +L + P P S P+R+ G + PK S+ P +
Sbjct: 763 SSPRSKAKSRLSLRRSLSGSSPCP-KQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSP 821
Query: 86 GRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQA- 144
++ S PS Q S S ++P P++++ QG T S PQ +
Sbjct: 822 PPKQKSKTPSRQ-------SHSSSSPHPKVKSGTPPRQG-SITSPQANEQSVTPQRRSCF 873
Query: 145 -GSPSKEDKKQ 154
SP E K +
Sbjct: 874 ESSPDPELKSR 884
Score = 33.5 bits (75), Expect = 2.6
Identities = 30/131 (22%), Positives = 49/131 (37%), Gaps = 9/131 (6%)
Query: 34 KSKSEANLIPSQE-----PFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRR 88
K KS PS E P P + + G L TP EP + P +A
Sbjct: 343 KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN--PPSEASPT 400
Query: 89 RNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQAGSPS 148
R+ PP + P + P SSS + P Q + ++ + + + + SP+
Sbjct: 401 RDRSPP--KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT 458
Query: 149 KEDKKQANIKR 159
+++ KR
Sbjct: 459 SKNRSHGRAKR 469
Score = 32.3 bits (72), Expect = 5.9
Identities = 28/101 (27%), Positives = 40/101 (39%), Gaps = 7/101 (6%)
Query: 35 SKSEANLIPSQEPFPASDNSGETPQRNGE-GHTLPKTPSQAE-----PASHKGPKDAGRR 88
+K+ + + P PAS GE E G T + PS E P+S KD ++
Sbjct: 284 AKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKK 343
Query: 89 RNSLPPSHQKPPRNPLSSSDAAPSPEL-QANGTGTQGLEAT 128
S P R+ AP+P L + +G Q L T
Sbjct: 344 EKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATT 384
>gi|164663810 ribosomal modification protein rimK-like family member
A [Homo sapiens]
Length = 391
Score = 41.2 bits (95), Expect = 0.013
Identities = 40/173 (23%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 411 WTEDDLQQGKRISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESA 470
WT +L G + +P D + G +D + ++ AE +G+P+++K++ G GK + A
Sbjct: 113 WTFQELA-GHGVPMP-DTFSYGGHEDFSKMIDEAEPLGYPVVVKSTRGHRGKAVFLARDK 170
Query: 471 EDFPILFRQVQSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKI 530
+ ++ ++ P K + + +++++ G V CS R Q
Sbjct: 171 HHLSDICHLIRHDV---PYLFQKYVKESHGKDIRVVV--VGGQVIGSMLRCSTDGRMQSN 225
Query: 531 VEEAPATI-APLAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELN 582
+ PL E +Q AI+++ +G G ++ L DGSF E N
Sbjct: 226 CSLGGVGVKCPLT--EQGKQLAIQVSNILGMDFCG-IDLLIMDDGSFVVCEAN 275
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 40.8 bits (94), Expect = 0.017
Identities = 57/228 (25%), Positives = 93/228 (40%), Gaps = 39/228 (17%)
Query: 26 MTDSKPIT--------KSKSEANLIPSQEPFPASDNSGETPQRNGEGHTL--PKTPSQAE 75
MTD+K +T S + ++P P S + P G+GHT P T QA
Sbjct: 658 MTDTKTVTTPGSSFTASGHSPSEIVPQDAP-TISAATTFAPAPTGDGHTTQAPTTALQAA 716
Query: 76 PASHK---GP-------KDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGTGTQGL 125
P+SH GP K + S P +S+ A+ SP+ A T T
Sbjct: 717 PSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQA 776
Query: 126 EATDTNGLSSSARP---------QGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSD 176
E+T+ +G + ++ P G S S + + T+ G +SS+
Sbjct: 777 ESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTS---GETTRFSSN 833
Query: 177 EDSVAGSSRESTR-KGSRASLGALSLEAYLTTGEAETRVP-TMRPSMS 222
+ +++ +T + AS GA+ ++TG A + VP T P++S
Sbjct: 834 PSRDSHTTQSTTELLSASASHGAIP----VSTGMASSIVPGTFHPTLS 877
>gi|21361684 G patch domain containing 1 [Homo sapiens]
Length = 931
Score = 40.8 bits (94), Expect = 0.017
Identities = 40/166 (24%), Positives = 68/166 (40%), Gaps = 17/166 (10%)
Query: 42 IPSQEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPR 101
+P P + S E ++ G + PS+ + + H+ +D+ SL S +PP+
Sbjct: 653 LPETASLPTTQASSEKVSQH-RGPDKSRKPSRWDTSKHEKKEDSISEFLSLARSKAEPPK 711
Query: 102 ---NPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIK 158
+PL + + +PEL AN T + ++A G S +A S D+K ++
Sbjct: 712 QQSSPLVNKEEEHAPELSANQTVNKDVDA-QAEGEGSRPSMDLFRAIFASSSDEKSSS-- 768
Query: 159 RQLMTNFILGSFDDYSSDEDSVAGSSRESTRKGSRASLGALSLEAY 204
S D+ ED AGS + + LG S A+
Sbjct: 769 ----------SEDEQGDSEDDQAGSGEANFQSSQDTDLGETSSVAH 804
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 39.7 bits (91), Expect = 0.037
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 8/91 (8%)
Query: 31 PITKSKSEANLIPSQEPF-----PASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDA 85
P+++ S A PS P P PQR P + PAS P
Sbjct: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPV 395
Query: 86 GRRRNSLPPSHQKPP---RNPLSSSDAAPSP 113
+RR+ +PPS Q P R+P+ S AP P
Sbjct: 396 PQRRSPVPPSCQSPSPQRRSPVPPSCPAPQP 426
>gi|209862975 MAP-kinase activating death domain-containing protein
isoform b [Homo sapiens]
Length = 1565
Score = 39.3 bits (90), Expect = 0.048
Identities = 50/225 (22%), Positives = 88/225 (39%), Gaps = 22/225 (9%)
Query: 52 DNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAP 111
D +G+TP + H S+ E + K+A S + PP SS+ A+
Sbjct: 649 DINGDTPNVDPLTHAALGDASEVEIDELQNQKEAEEPGPDSENSQENPPLRSSSSTTASS 708
Query: 112 SPELQANGTGTQGLEATDTNGLS----SSARPQGQQAGSPSKEDKKQANI---KRQLMTN 164
SP +G ++ ++T+ + + S P + S D++QA I ++L+
Sbjct: 709 SPSTVIHGANSEPADSTEMDDKAAVGVSKPLPSVPPSIGKSNVDRRQAEIGEGAQKLLRP 768
Query: 165 FILGSFDDYSSDEDSVAGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGL 224
L D ++ DS A S + S G + ++ + R + S+S L
Sbjct: 769 NSLRLASDSDAESDSRASSPNSTVSNTSTEGFGGI-----MSFASSLYRNHSTSFSLSNL 823
Query: 225 HLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNG 269
L +G K A+P + FG + ++E V A G
Sbjct: 824 TLPTKGAREK----------ATPFPSLKVFGLNTLMEIVTEAGPG 858
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 39.3 bits (90), Expect = 0.048
Identities = 37/134 (27%), Positives = 58/134 (43%), Gaps = 8/134 (5%)
Query: 29 SKPITKSKSEANLIPSQEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRR 88
+KP +K+ +L Q P + D+S ++ + E KT A K K AG
Sbjct: 445 TKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEE-EKTSKSA--VKKKPQKVAGGA 501
Query: 89 RNSLPPSHQK---PPRNPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQA- 144
S P S +K N SS D++ E + G G+ +A NG S+ G+ A
Sbjct: 502 APSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAK 561
Query: 145 -GSPSKEDKKQANI 157
+E+KK+A +
Sbjct: 562 NSEEEEEEKKKAAV 575
Score = 32.0 bits (71), Expect = 7.7
Identities = 33/149 (22%), Positives = 56/149 (37%), Gaps = 21/149 (14%)
Query: 42 IPSQEPFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPR 101
+ Q+P +S++S + + E P T + A+ K PP +K
Sbjct: 313 VEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTK------------PPPAKKAAE 360
Query: 102 NPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQL 161
+ SSD+ S + +A T N + A A P+ K+ ++L
Sbjct: 361 SSSDSSDSDSSEDDEAPSKPA----GTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL 416
Query: 162 MTNFILGSFDDYSSDEDSVAGSSRESTRK 190
+T D SS E+ + S E T+K
Sbjct: 417 LTRKA-----DSSSSEEESSSSEEEKTKK 440
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 38.9 bits (89), Expect = 0.063
Identities = 36/142 (25%), Positives = 58/142 (40%), Gaps = 20/142 (14%)
Query: 34 KSKSEANLIPSQE-PFPASDNSGETPQRNGEGHTLPKTPSQAEPASHKGPKDAGRRRNSL 92
++KS+ ++PS P P S + + +T + +E S + K A +R S
Sbjct: 354 RAKSQEEVLPSSTTPSPGGALSPSGQPSSSATEVVLRTRTASE-GSEQPKKRASIQRTSA 412
Query: 93 PPSHQKPPR--------------NPLSSSDAAPSPELQANGTGTQGLEATDTNGLSSSAR 138
PPS PPR +P +S +P+ + GTGT A+ L S
Sbjct: 413 PPSRPPPPRATASPRPSSGNIPSSPTASGGGSPTSPRASLGTGT----ASPRTSLEVSPN 468
Query: 139 PQGQQAGSPSKEDKKQANIKRQ 160
P+ + + E K+ NI Q
Sbjct: 469 PEPPEKPVRTPEAKENENIHNQ 490
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,007,782
Number of Sequences: 37866
Number of extensions: 4361815
Number of successful extensions: 12947
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 12478
Number of HSP's gapped (non-prelim): 520
length of query: 2458
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2339
effective length of database: 13,741,464
effective search space: 32141284296
effective search space used: 32141284296
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.