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Search of human proteins with 55956916
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55956916 myosin IE [Homo sapiens]
(1108 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55956916 myosin IE [Homo sapiens] 2241 0.0
gi|27544941 myosin IF [Homo sapiens] 1605 0.0
gi|194328685 myosin IB isoform 1 [Homo sapiens] 624 e-178
gi|44889481 myosin IB isoform 2 [Homo sapiens] 624 e-178
gi|240120050 myosin IB isoform 1 [Homo sapiens] 624 e-178
gi|124494247 myosin IC isoform b [Homo sapiens] 608 e-174
gi|124494238 myosin IC isoform a [Homo sapiens] 608 e-174
gi|124494240 myosin IC isoform c [Homo sapiens] 608 e-174
gi|254028267 myosin 1H [Homo sapiens] 582 e-166
gi|4885503 myosin IA [Homo sapiens] 581 e-165
gi|51100974 myosin ID [Homo sapiens] 564 e-160
gi|239582755 myosin IG [Homo sapiens] 531 e-150
gi|153945715 myosin VC [Homo sapiens] 484 e-136
gi|122937345 myosin VB [Homo sapiens] 480 e-135
gi|215982794 myosin VA isoform 2 [Homo sapiens] 478 e-134
gi|215982791 myosin VA isoform 1 [Homo sapiens] 478 e-134
gi|154354979 myosin X [Homo sapiens] 474 e-133
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 474 e-133
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 474 e-133
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 474 e-133
gi|122937512 myosin VIIB [Homo sapiens] 462 e-129
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 454 e-127
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 452 e-127
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 452 e-127
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 451 e-126
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 451 e-126
gi|118402590 myosin XV [Homo sapiens] 451 e-126
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 450 e-126
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 450 e-126
gi|156104908 myosin heavy chain 6 [Homo sapiens] 439 e-123
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 2241 bits (5808), Expect = 0.0
Identities = 1108/1108 (100%), Positives = 1108/1108 (100%)
Query: 1 MGSKGVYQYHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVN 60
MGSKGVYQYHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVN
Sbjct: 1 MGSKGVYQYHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVN 60
Query: 61 PFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTV 120
PFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTV
Sbjct: 61 PFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTV 120
Query: 121 AAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSP 180
AAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSP
Sbjct: 121 AAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSP 180
Query: 181 GGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSL 240
GGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSL
Sbjct: 181 GGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSL 240
Query: 241 SGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVE 300
SGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVE
Sbjct: 241 SGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVE 300
Query: 301 SEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH 360
SEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH
Sbjct: 301 SEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH 360
Query: 361 ARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 420
ARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT
Sbjct: 361 ARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 420
Query: 421 LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT 480
LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT
Sbjct: 421 LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT 480
Query: 481 LLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELP 540
LLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELP
Sbjct: 481 LLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELP 540
Query: 541 FIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEE 600
FIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEE
Sbjct: 541 FIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEE 600
Query: 601 SRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQ 660
SRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQ
Sbjct: 601 SRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQ 660
Query: 661 SVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMRE 720
SVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMRE
Sbjct: 661 SVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMRE 720
Query: 721 EASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGV 780
EASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGV
Sbjct: 721 EASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGV 780
Query: 781 KRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQE 840
KRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQE
Sbjct: 781 KRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQE 840
Query: 841 YDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFH 900
YDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFH
Sbjct: 841 YDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFH 900
Query: 901 QGFGDLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPPG 960
QGFGDLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPPG
Sbjct: 901 QGFGDLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPPG 960
Query: 961 YHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLKV 1020
YHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLKV
Sbjct: 961 YHQNGVIRNQYVPYPHAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPESLDFLKV 1020
Query: 1021 PDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDI 1080
PDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDI
Sbjct: 1021 PDQGAAGVRRQTTSRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSFNANDIIDI 1080
Query: 1081 IKEDPSGWWTGRLRGKQGLFPNNYVTKI 1108
IKEDPSGWWTGRLRGKQGLFPNNYVTKI
Sbjct: 1081 IKEDPSGWWTGRLRGKQGLFPNNYVTKI 1108
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 1605 bits (4157), Expect = 0.0
Identities = 796/1116 (71%), Positives = 933/1116 (83%), Gaps = 26/1116 (2%)
Query: 1 MGSKGVYQYHWQSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVN 60
MGSK ++HWQSHNVK SGVDDMVLL +ITE++I NL+KR+MDDYIFTYIGSVLISVN
Sbjct: 1 MGSKE--RFHWQSHNVKQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVN 58
Query: 61 PFKQMPYFGEKEIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTV 120
PFKQMPYF ++EI++YQGAAQYENPPHIYAL DNMYRNM+ID ENQCVIISGESGAGKTV
Sbjct: 59 PFKQMPYFTDREIDLYQGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTV 118
Query: 121 AAKYIMSYISRVSGGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSP 180
AAKYIM YIS+VSGGG KVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFS
Sbjct: 119 AAKYIMGYISKVSGGGEKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSR 178
Query: 181 GGEPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSL 240
GGEPDGGKISNFLLEKSRVVM+N ER+FHI+YQL+EGAS EQ+ +LG+ + DYYYYL+
Sbjct: 179 GGEPDGGKISNFLLEKSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQ 238
Query: 241 SGSYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVE 300
S +Y+VD DDR +F ETL AM VIGI Q LVLQ+VAGILHLGNISF E GNYA VE
Sbjct: 239 SDTYQVDGTDDRSDFGETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISFCEDGNYARVE 298
Query: 301 SEEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH 360
S + LAFPAYLLGI+ RL+EKLTSR+MDS+WGG+SESI+VTLNVEQA YTRDALAK L+
Sbjct: 299 SVDLLAFPAYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLY 358
Query: 361 ARVFDFLVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 420
AR+FDFLV++IN+AM+K EEY+IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT
Sbjct: 359 ARLFDFLVEAINRAMQKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 418
Query: 421 LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT 480
LKAEQEEYVQEGIRWTPI+YFNNK+VCDLIENK++PPGIMS+LDDVCATMHA G GADQT
Sbjct: 419 LKAEQEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQT 478
Query: 481 LLQKLQMQIGSHEHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELP 540
LLQKLQ +G+HEHFNSW+ GF+IHHYAGKVSYD+ GFCERNRDVLF DLIELMQ+SE
Sbjct: 479 LLQKLQAAVGTHEHFNSWSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQA 538
Query: 541 FIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEE 600
F++ LFPE L DKKGRP+TAGSKIKKQANDLV+TLM+CTPHYIRCIKPNETK+PRDWEE
Sbjct: 539 FLRMLFPEKLDGDKKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEE 598
Query: 601 SRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQ 660
+RVKHQVEYLGLKENIRVRRAG+AYRR F KFLQRYAILT TWP W+G+E+QGV HLL+
Sbjct: 599 NRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLR 658
Query: 661 SVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMRE 720
+VNM+ DQ+Q+G +KVF+K PESLFLLEE+RERK+DG+AR IQK+WR+ VA +KY +MRE
Sbjct: 659 AVNMEPDQYQMGSTKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMRE 718
Query: 721 EASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYDRRFKGV 780
EAS++LLNKKERRRNSINRNF+GDY+G+EE PEL+QF+GKRE++DFAD+VTKYDRRFK +
Sbjct: 719 EASNILLNKKERRRNSINRNFVGDYLGLEERPELRQFLGKRERVDFADSVTKYDRRFKPI 778
Query: 781 KRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQE 840
KRDL+LTPKC+Y+IGREKVK+GP+KG V EVLK+K++I+ + VSLST QDD FIL E
Sbjct: 779 KRDLILTPKCVYVIGREKVKKGPEKGQVCEVLKKKVDIQALRGVSLSTRQDDFFILQEDA 838
Query: 841 YDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFH 900
DS LESVFKTEF+SLL KR+EE T++ LPL FS+TL+ ++KKE WG GG+R V F
Sbjct: 839 ADSFLESVFKTEFVSLLCKRFEEATRRPLPLTFSDTLQFRVKKEGWG---GGGTRSVTFS 895
Query: 901 QGFGDLAVLKPSNKVLQVSIGPGLPKNSRPTRRNTTQNTGYSSGTQNANYPVRAAPPPP- 959
+GFGDLAVLK + L VS+G GLPK+S+PTR+ + +++ P RAAP PP
Sbjct: 896 RGFGDLAVLKVGGRTLTVSVGDGLPKSSKPTRKGMAK----GKPRRSSQAPTRAAPAPPR 951
Query: 960 GYHQNGV---IRNQYVPYP--HAPGSQRSNQKSLYTSMARPPLPRQQSTSSDRVSQTPES 1014
G +NGV R +P G+ R + TS+ PR + S +
Sbjct: 952 GMDRNGVPPSARGGPLPLEIMSGGGTHRPPRGPPSTSLGASRRPRARPPSE-------HN 1004
Query: 1015 LDFLKVPDQGAAGVRRQTT--SRPPPAGGRPKPQPKPKPQVPQCKALYAYDAQDTDELSF 1072
+FL VPDQG AG++R+ + RP P GRPKPQ P+ P+C+ALY Y QD DELSF
Sbjct: 1005 TEFLNVPDQGMAGMQRKRSVGQRPVPGVGRPKPQ--PRTHGPRCRALYQYVGQDVDELSF 1062
Query: 1073 NANDIIDIIKEDPSGWWTGRLRGKQGLFPNNYVTKI 1108
N N++I+I+ EDPSGWW GRL G++GLFP NYV KI
Sbjct: 1063 NVNEVIEILMEDPSGWWKGRLHGQEGLFPGNYVEKI 1098
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 624 bits (1608), Expect = e-178
Identities = 335/724 (46%), Positives = 469/724 (64%), Gaps = 33/724 (4%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
GV DMVLL + E + + NLKKR+ I+TYIGSV+ISVNP++ +P + +++E Y+
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKV 139
YE PHI+AL+D YR++ ++QC++I+GESGAGKT A+K +MSY++ V G G +V
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 140 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRV 199
VK+ +LQSNP+LEAFGNAKTVRN+NSSRFGKY +I+F G+P GG ISN+LLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 200 VMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQET 258
V + GER+FH+FYQL+ GAS E + L + Y YLSL S KV+ +DD F+
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLD-SAKVNGVDDAANFRTV 254
Query: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVG-----NYAAVESEEFLAFPAYLLG 313
+AM ++G E VL +VA +L LGNI FK + + ++ + L L G
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 314 INQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINK 373
I+Q L+ + R +++ K E + TLNV QA Y RDALAK L++R+F +LV+ IN+
Sbjct: 315 IDQSVLERAFSFRTVEA----KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINE 370
Query: 374 AMEKDHE--EYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQE 431
+++ + + +GVLDIYGFEIF+ N FEQF IN+ NEKLQQIFIELTLK EQEEY++E
Sbjct: 371 SIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 432 GIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGS 491
I WT I+YFNN I+CDLIEN N GI+++LD+ C G D+T L+KL +
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTN--GILAMLDEECL---RPGTVTDETFLEKLNQVCAT 485
Query: 492 HEHFNSW--------------NQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSS 537
H+HF S + F I HYAGKV Y ++GF ++N D+L+ DL + M +
Sbjct: 486 HQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKA 545
Query: 538 ELPFIKSLFPENLQAD-KKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
IKSLFPE A RP TAGS+ K L+ L P+YIRCIKPN+ K
Sbjct: 546 SHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAH 605
Query: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656
+ E+ V HQ+ YLGL EN+RVRRAGYA+R+ ++ L+RY +L K TWP W+G + GV
Sbjct: 606 IFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVE 665
Query: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716
L + + +++ GRSK+FI+ P +LF LE++R+++ + A +IQK +R + R ++
Sbjct: 666 VLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFL 725
Query: 717 QMRE 720
M++
Sbjct: 726 LMKK 729
Score = 50.1 bits (118), Expect = 1e-05
Identities = 78/344 (22%), Positives = 146/344 (42%), Gaps = 63/344 (18%)
Query: 599 EESRVKHQVE-----YLGLKENIRVRRAGYA------YRRIFQKFLQRYAILTKATWPSW 647
EE+R KH V +LGLK R+ A Y Q+ +Q+Y + K PS
Sbjct: 833 EEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSL 892
Query: 648 QGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWR 707
+K N S + LFL +E K + +K
Sbjct: 893 SPIDK----------NWPSRPY--------------LFLDSTHKELKRIFHLWRCKKYRD 928
Query: 708 KFVARKKYV-QMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGK-REKID 765
+F ++K + + + EAS+L +KK +S+ + F G Y+ + ++P+ ++ EKI
Sbjct: 929 QFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKII 988
Query: 766 FADTVTKYDR-RFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSV 824
A+ V K +R K R LLT L L ++ + +K ++ + + V
Sbjct: 989 IAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQ-----------IKSEVPLVDVTKV 1037
Query: 825 SLSTMQDDIFILHEQE-------YDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTL 877
S+S+ D F +H +E D L S E + L + +T+++L ++ S+
Sbjct: 1038 SMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEF 1097
Query: 878 ELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLK-PSNKVLQVSI 920
++ +++ + +Q +Q G + K +N++L+V++
Sbjct: 1098 LVQFRQDK------VCVKFIQGNQKNGSVPTCKRKNNRLLEVAV 1135
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 624 bits (1608), Expect = e-178
Identities = 335/724 (46%), Positives = 469/724 (64%), Gaps = 33/724 (4%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
GV DMVLL + E + + NLKKR+ I+TYIGSV+ISVNP++ +P + +++E Y+
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKV 139
YE PHI+AL+D YR++ ++QC++I+GESGAGKT A+K +MSY++ V G G +V
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 140 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRV 199
VK+ +LQSNP+LEAFGNAKTVRN+NSSRFGKY +I+F G+P GG ISN+LLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 200 VMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQET 258
V + GER+FH+FYQL+ GAS E + L + Y YLSL S KV+ +DD F+
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLD-SAKVNGVDDAANFRTV 254
Query: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVG-----NYAAVESEEFLAFPAYLLG 313
+AM ++G E VL +VA +L LGNI FK + + ++ + L L G
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 314 INQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINK 373
I+Q L+ + R +++ K E + TLNV QA Y RDALAK L++R+F +LV+ IN+
Sbjct: 315 IDQSVLERAFSFRTVEA----KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINE 370
Query: 374 AMEKDHE--EYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQE 431
+++ + + +GVLDIYGFEIF+ N FEQF IN+ NEKLQQIFIELTLK EQEEY++E
Sbjct: 371 SIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 432 GIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGS 491
I WT I+YFNN I+CDLIEN N GI+++LD+ C G D+T L+KL +
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTN--GILAMLDEECL---RPGTVTDETFLEKLNQVCAT 485
Query: 492 HEHFNSW--------------NQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSS 537
H+HF S + F I HYAGKV Y ++GF ++N D+L+ DL + M +
Sbjct: 486 HQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKA 545
Query: 538 ELPFIKSLFPENLQAD-KKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
IKSLFPE A RP TAGS+ K L+ L P+YIRCIKPN+ K
Sbjct: 546 SHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAH 605
Query: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656
+ E+ V HQ+ YLGL EN+RVRRAGYA+R+ ++ L+RY +L K TWP W+G + GV
Sbjct: 606 IFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVE 665
Query: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716
L + + +++ GRSK+FI+ P +LF LE++R+++ + A +IQK +R + R ++
Sbjct: 666 VLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFL 725
Query: 717 QMRE 720
M++
Sbjct: 726 LMKK 729
Score = 46.6 bits (109), Expect = 1e-04
Identities = 56/248 (22%), Positives = 115/248 (46%), Gaps = 28/248 (11%)
Query: 684 LFLLEEMRERKYDGYARVIQKSWRKFVARKKYV-QMREEASDLLLNKKERRRNSINRNFI 742
LFL +E K + +K +F ++K + + + EAS+L +KK +S+ + F
Sbjct: 847 LFLDSTHKELKRIFHLWRCKKYRDQFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQ 906
Query: 743 GDYIGMEEHPELQQFVGK-REKIDFADTVTKYDR-RFKGVKRDLLLTPKCLYLIGREKVK 800
G Y+ + ++P+ ++ EKI A+ V K +R K R LLT L L ++ +
Sbjct: 907 GAYLEINKNPKYKKLKDAIEEKIIIAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQ 966
Query: 801 QGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIFILHEQE-------YDSLLESVFKTEF 853
+K ++ + + VS+S+ D F +H +E D L S E
Sbjct: 967 -----------IKSEVPLVDVTKVSMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEM 1015
Query: 854 LSLLAKRYEEKTQKQLPLKFSNTLELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLK-PS 912
+ L + +T+++L ++ S+ ++ +++ + +Q +Q G + K +
Sbjct: 1016 ATKLYRTTLSQTKQKLNIEISDEFLVQFRQDK------VCVKFIQGNQKNGSVPTCKRKN 1069
Query: 913 NKVLQVSI 920
N++L+V++
Sbjct: 1070 NRLLEVAV 1077
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 624 bits (1608), Expect = e-178
Identities = 335/724 (46%), Positives = 469/724 (64%), Gaps = 33/724 (4%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
GV DMVLL + E + + NLKKR+ I+TYIGSV+ISVNP++ +P + +++E Y+
Sbjct: 16 GVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNR 75
Query: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKV 139
YE PHI+AL+D YR++ ++QC++I+GESGAGKT A+K +MSY++ V G G +V
Sbjct: 76 NFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEV 135
Query: 140 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRV 199
VK+ +LQSNP+LEAFGNAKTVRN+NSSRFGKY +I+F G+P GG ISN+LLEKSRV
Sbjct: 136 NQVKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRV 195
Query: 200 VMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQET 258
V + GER+FH+FYQL+ GAS E + L + Y YLSL S KV+ +DD F+
Sbjct: 196 VKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLD-SAKVNGVDDAANFRTV 254
Query: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVG-----NYAAVESEEFLAFPAYLLG 313
+AM ++G E VL +VA +L LGNI FK + + ++ + L L G
Sbjct: 255 RNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKNELKEICELTG 314
Query: 314 INQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINK 373
I+Q L+ + R +++ K E + TLNV QA Y RDALAK L++R+F +LV+ IN+
Sbjct: 315 IDQSVLERAFSFRTVEA----KQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINE 370
Query: 374 AMEKDHE--EYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQE 431
+++ + + +GVLDIYGFEIF+ N FEQF IN+ NEKLQQIFIELTLK EQEEY++E
Sbjct: 371 SIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIRE 430
Query: 432 GIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGS 491
I WT I+YFNN I+CDLIEN N GI+++LD+ C G D+T L+KL +
Sbjct: 431 DIEWTHIDYFNNAIICDLIENNTN--GILAMLDEECL---RPGTVTDETFLEKLNQVCAT 485
Query: 492 HEHFNSW--------------NQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSS 537
H+HF S + F I HYAGKV Y ++GF ++N D+L+ DL + M +
Sbjct: 486 HQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKA 545
Query: 538 ELPFIKSLFPENLQAD-KKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
IKSLFPE A RP TAGS+ K L+ L P+YIRCIKPN+ K
Sbjct: 546 SHALIKSLFPEGNPAKINLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAH 605
Query: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656
+ E+ V HQ+ YLGL EN+RVRRAGYA+R+ ++ L+RY +L K TWP W+G + GV
Sbjct: 606 IFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVE 665
Query: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716
L + + +++ GRSK+FI+ P +LF LE++R+++ + A +IQK +R + R ++
Sbjct: 666 VLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFL 725
Query: 717 QMRE 720
M++
Sbjct: 726 LMKK 729
Score = 50.1 bits (118), Expect = 1e-05
Identities = 78/344 (22%), Positives = 146/344 (42%), Gaps = 63/344 (18%)
Query: 599 EESRVKHQVE-----YLGLKENIRVRRAGYA------YRRIFQKFLQRYAILTKATWPSW 647
EE+R KH V +LGLK R+ A Y Q+ +Q+Y + K PS
Sbjct: 833 EEARRKHAVAVIWAYWLGLKVRREYRKFFRANAGKKIYEFTLQRIVQKYFLEMKNKMPSL 892
Query: 648 QGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWR 707
+K N S + LFL +E K + +K
Sbjct: 893 SPIDK----------NWPSRPY--------------LFLDSTHKELKRIFHLWRCKKYRD 928
Query: 708 KFVARKKYV-QMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGK-REKID 765
+F ++K + + + EAS+L +KK +S+ + F G Y+ + ++P+ ++ EKI
Sbjct: 929 QFTDQQKLIYEEKLEASELFKDKKALYPSSVGQPFQGAYLEINKNPKYKKLKDAIEEKII 988
Query: 766 FADTVTKYDR-RFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSV 824
A+ V K +R K R LLT L L ++ + +K ++ + + V
Sbjct: 989 IAEVVNKINRANGKSTSRIFLLTNNNLLLADQKSGQ-----------IKSEVPLVDVTKV 1037
Query: 825 SLSTMQDDIFILHEQE-------YDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTL 877
S+S+ D F +H +E D L S E + L + +T+++L ++ S+
Sbjct: 1038 SMSSQNDGFFAVHLKEGSEAASKGDFLFSSDHLIEMATKLYRTTLSQTKQKLNIEISDEF 1097
Query: 878 ELKLKKENWGPWSAGGSRQVQFHQGFGDLAVLK-PSNKVLQVSI 920
++ +++ + +Q +Q G + K +N++L+V++
Sbjct: 1098 LVQFRQDK------VCVKFIQGNQKNGSVPTCKRKNNRLLEVAV 1135
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 608 bits (1569), Expect = e-174
Identities = 331/726 (45%), Positives = 467/726 (64%), Gaps = 34/726 (4%)
Query: 20 GVDDMVLLSKIT-ENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78
GV D VLL T E + +ENL++R+ ++ I+TYIG VL+SVNP++ + + + +E Y+G
Sbjct: 28 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 87
Query: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138
+ YE PPH++A+AD +YR + +R +Q V+ISGESGAGKT A K ++ + + +
Sbjct: 88 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 147
Query: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198
V+D +LQSNP+LEAFGNAKT+RN+NSSRFGKY ++QF G P GG I ++LLEKSR
Sbjct: 148 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 207
Query: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQE 257
VV +N GER+FHIFYQL+EG E LG+ + Y YL KV I+D+ +++
Sbjct: 208 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 267
Query: 258 TLHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEEFLAFPAYLLGIN 315
A+ VI +E +L IVA +LHLGNI F E N A V +E L + LL +
Sbjct: 268 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVE 326
Query: 316 QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM 375
L+E LT R++ + K E + LN+EQA Y RDALAKA+++R F +LV IN+++
Sbjct: 327 GSTLREALTHRKIIA----KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 382
Query: 376 -EKDHEEYN------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 428
KD E + +G+LDIYGFE+FQ N FEQFCIN+ NEKLQQ+FIELTLK+EQEEY
Sbjct: 383 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 442
Query: 429 VQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQ 488
EGI W P++YFNNKI+CDL+E K GI+SILD+ C GE D T L+KL+
Sbjct: 443 EAEGIAWEPVQYFNNKIICDLVEEKFK--GIISILDEECL---RPGEATDLTFLEKLEDT 497
Query: 489 IGSHEHF-----------NSWNQG-FIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQS 536
+ H HF S +G F + HYAG+V+Y + GF ++N D+LF +L E M S
Sbjct: 498 VKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 557
Query: 537 SELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
S+ P + F + +DKK RP T ++ K LV L P Y+RCIKPN+ K+P
Sbjct: 558 SKNPIMSQCFDRSELSDKK-RPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 616
Query: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656
++E ++HQV+YLGL EN+RVRRAG+AYRR ++ FLQRY L TWP+W G + GV
Sbjct: 617 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 676
Query: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716
L++ + +++++GR+K+FI+ P++LF E+ E + A IQ +WR F R+K++
Sbjct: 677 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 736
Query: 717 QMREEA 722
+++ A
Sbjct: 737 RVKRSA 742
Score = 69.3 bits (168), Expect = 2e-11
Identities = 47/148 (31%), Positives = 74/148 (50%), Gaps = 22/148 (14%)
Query: 698 YARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEE-HPELQQ 756
Y R I W K+ +Q + AS++ KK+ S+ R FI +G +E P + Q
Sbjct: 840 YCRSISPEW------KQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQ 893
Query: 757 FVGKREKIDFADTVTKYDRR-FKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRK 815
+G E I +A V KYDR+ +K R LLLTP + ++ KVKQ +
Sbjct: 894 ALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQ-------------R 939
Query: 816 IEIERILSVSLSTMQDDIFILHEQEYDS 843
I+ + +S+S++ D +F+LH Q D+
Sbjct: 940 IDYANLTGISVSSLSDSLFVLHVQRADN 967
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 608 bits (1569), Expect = e-174
Identities = 331/726 (45%), Positives = 467/726 (64%), Gaps = 34/726 (4%)
Query: 20 GVDDMVLLSKIT-ENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78
GV D VLL T E + +ENL++R+ ++ I+TYIG VL+SVNP++ + + + +E Y+G
Sbjct: 47 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 106
Query: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138
+ YE PPH++A+AD +YR + +R +Q V+ISGESGAGKT A K ++ + + +
Sbjct: 107 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 166
Query: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198
V+D +LQSNP+LEAFGNAKT+RN+NSSRFGKY ++QF G P GG I ++LLEKSR
Sbjct: 167 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 226
Query: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQE 257
VV +N GER+FHIFYQL+EG E LG+ + Y YL KV I+D+ +++
Sbjct: 227 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 286
Query: 258 TLHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEEFLAFPAYLLGIN 315
A+ VI +E +L IVA +LHLGNI F E N A V +E L + LL +
Sbjct: 287 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVE 345
Query: 316 QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM 375
L+E LT R++ + K E + LN+EQA Y RDALAKA+++R F +LV IN+++
Sbjct: 346 GSTLREALTHRKIIA----KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 401
Query: 376 -EKDHEEYN------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 428
KD E + +G+LDIYGFE+FQ N FEQFCIN+ NEKLQQ+FIELTLK+EQEEY
Sbjct: 402 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 461
Query: 429 VQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQ 488
EGI W P++YFNNKI+CDL+E K GI+SILD+ C GE D T L+KL+
Sbjct: 462 EAEGIAWEPVQYFNNKIICDLVEEKFK--GIISILDEECL---RPGEATDLTFLEKLEDT 516
Query: 489 IGSHEHF-----------NSWNQG-FIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQS 536
+ H HF S +G F + HYAG+V+Y + GF ++N D+LF +L E M S
Sbjct: 517 VKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 576
Query: 537 SELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
S+ P + F + +DKK RP T ++ K LV L P Y+RCIKPN+ K+P
Sbjct: 577 SKNPIMSQCFDRSELSDKK-RPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 635
Query: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656
++E ++HQV+YLGL EN+RVRRAG+AYRR ++ FLQRY L TWP+W G + GV
Sbjct: 636 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 695
Query: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716
L++ + +++++GR+K+FI+ P++LF E+ E + A IQ +WR F R+K++
Sbjct: 696 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 755
Query: 717 QMREEA 722
+++ A
Sbjct: 756 RVKRSA 761
Score = 69.3 bits (168), Expect = 2e-11
Identities = 47/148 (31%), Positives = 74/148 (50%), Gaps = 22/148 (14%)
Query: 698 YARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEE-HPELQQ 756
Y R I W K+ +Q + AS++ KK+ S+ R FI +G +E P + Q
Sbjct: 859 YCRSISPEW------KQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQ 912
Query: 757 FVGKREKIDFADTVTKYDRR-FKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRK 815
+G E I +A V KYDR+ +K R LLLTP + ++ KVKQ +
Sbjct: 913 ALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQ-------------R 958
Query: 816 IEIERILSVSLSTMQDDIFILHEQEYDS 843
I+ + +S+S++ D +F+LH Q D+
Sbjct: 959 IDYANLTGISVSSLSDSLFVLHVQRADN 986
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 608 bits (1569), Expect = e-174
Identities = 331/726 (45%), Positives = 467/726 (64%), Gaps = 34/726 (4%)
Query: 20 GVDDMVLLSKIT-ENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78
GV D VLL T E + +ENL++R+ ++ I+TYIG VL+SVNP++ + + + +E Y+G
Sbjct: 12 GVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRG 71
Query: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138
+ YE PPH++A+AD +YR + +R +Q V+ISGESGAGKT A K ++ + + +
Sbjct: 72 VSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPER 131
Query: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198
V+D +LQSNP+LEAFGNAKT+RN+NSSRFGKY ++QF G P GG I ++LLEKSR
Sbjct: 132 GGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSR 191
Query: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQE 257
VV +N GER+FHIFYQL+EG E LG+ + Y YL KV I+D+ +++
Sbjct: 192 VVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKGQCAKVSSINDKSDWKV 251
Query: 258 TLHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEEFLAFPAYLLGIN 315
A+ VI +E +L IVA +LHLGNI F E N A V +E L + LL +
Sbjct: 252 VRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESN-AQVTTENQLKYLTRLLSVE 310
Query: 316 QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM 375
L+E LT R++ + K E + LN+EQA Y RDALAKA+++R F +LV IN+++
Sbjct: 311 GSTLREALTHRKIIA----KGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSL 366
Query: 376 -EKDHEEYN------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 428
KD E + +G+LDIYGFE+FQ N FEQFCIN+ NEKLQQ+FIELTLK+EQEEY
Sbjct: 367 ASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEY 426
Query: 429 VQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQ 488
EGI W P++YFNNKI+CDL+E K GI+SILD+ C GE D T L+KL+
Sbjct: 427 EAEGIAWEPVQYFNNKIICDLVEEKFK--GIISILDEECL---RPGEATDLTFLEKLEDT 481
Query: 489 IGSHEHF-----------NSWNQG-FIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQS 536
+ H HF S +G F + HYAG+V+Y + GF ++N D+LF +L E M S
Sbjct: 482 VKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCS 541
Query: 537 SELPFIKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
S+ P + F + +DKK RP T ++ K LV L P Y+RCIKPN+ K+P
Sbjct: 542 SKNPIMSQCFDRSELSDKK-RPETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPG 600
Query: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656
++E ++HQV+YLGL EN+RVRRAG+AYRR ++ FLQRY L TWP+W G + GV
Sbjct: 601 RFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVA 660
Query: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716
L++ + +++++GR+K+FI+ P++LF E+ E + A IQ +WR F R+K++
Sbjct: 661 VLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFL 720
Query: 717 QMREEA 722
+++ A
Sbjct: 721 RVKRSA 726
Score = 69.3 bits (168), Expect = 2e-11
Identities = 47/148 (31%), Positives = 74/148 (50%), Gaps = 22/148 (14%)
Query: 698 YARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEE-HPELQQ 756
Y R I W K+ +Q + AS++ KK+ S+ R FI +G +E P + Q
Sbjct: 824 YCRSISPEW------KQQLQQKAVASEIFKGKKDNYPQSVPRLFISTRLGTDEISPRVLQ 877
Query: 757 FVGKREKIDFADTVTKYDRR-FKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRK 815
+G E I +A V KYDR+ +K R LLLTP + ++ KVKQ +
Sbjct: 878 ALGS-EPIQYAVPVVKYDRKGYKPRSRQLLLTPNAVVIVEDAKVKQ-------------R 923
Query: 816 IEIERILSVSLSTMQDDIFILHEQEYDS 843
I+ + +S+S++ D +F+LH Q D+
Sbjct: 924 IDYANLTGISVSSLSDSLFVLHVQRADN 951
>gi|254028267 myosin 1H [Homo sapiens]
Length = 1022
Score = 582 bits (1499), Expect = e-166
Identities = 322/769 (41%), Positives = 477/769 (62%), Gaps = 41/769 (5%)
Query: 20 GVDDMVLLSKIT-ENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78
GV D VLL T E++ V+NL+KR+ ++ I+TYIG++L+SVNP++++ + ++E+YQG
Sbjct: 12 GVQDFVLLDAYTSESAFVDNLRKRFSENLIYTYIGTLLVSVNPYQELGIYTVSQMELYQG 71
Query: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138
+E PPH+YA+ADN YR M + N ++ISGESGAGKT A+K I+ Y +
Sbjct: 72 VNFFELPPHVYAIADNAYRMMCAELNNHFILISGESGAGKTEASKKILEYFAVTCPMTQS 131
Query: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198
+Q +D +L SNP+LEAFGNA+T+RN+NSSRFGKY +IQF G P GG I ++L+EKSR
Sbjct: 132 LQIARDRLLFSNPVLEAFGNARTLRNDNSSRFGKYMDIQFDFQGIPVGGHIISYLIEKSR 191
Query: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQE 257
VV +N GER+FHIFYQL+ G E+ LG+ Y YLS K I D+ +++
Sbjct: 192 VVYQNEGERNFHIFYQLLAGGEEERLSYLGLERDPQLYKYLSQGHCAKESSISDKNDWKT 251
Query: 258 TLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVG-NYAAVESEEFLAFPAYLLGINQ 316
+A +VI + + I+A +LHLGNI F+E A + + + A LLG++
Sbjct: 252 VSNAFSVIDFTEADLENLFGIIASVLHLGNIGFEEDDQGCATIPDTHEIKWIAKLLGVHP 311
Query: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM- 375
L E LT R++++ K+E + L +E + Y RDA+AKA++ R F +LV+ IN ++
Sbjct: 312 SVLLEALTHRKIEA----KTEEVICPLTLELSVYARDAMAKAVYGRTFTWLVNKINSSLV 367
Query: 376 EKDHEEYN-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIR 434
KD IG+LDIYGFE+F KNGFEQFCIN+ NEKLQQ+ IE TLKAEQ EY EGI
Sbjct: 368 NKDFTRKTVIGLLDIYGFEVFDKNGFEQFCINYCNEKLQQLLIERTLKAEQAEYEMEGIE 427
Query: 435 WTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEH 494
W PI+YFNNKI+CDL+E + GI+SILD+ C G D + L+KL+ ++G H H
Sbjct: 428 WEPIKYFNNKIICDLVEER--HKGIISILDEECI---RPGPATDLSFLEKLEEKVGKHAH 482
Query: 495 FNS-------------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPF 541
F + W + F + HYAG+V+Y GF E+N D+L+ L E++ S+
Sbjct: 483 FETRKLAGPKGRKRIGWME-FRLLHYAGEVTYCTKGFLEKNNDLLYRHLKEVLCKSKNII 541
Query: 542 IKSLFPENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEES 601
++ F + + + RP T G++ K + L+ TL+ P YIRCIKPN+ K+P +++
Sbjct: 542 LRECF-LLAELENRRRPPTVGTQFKNSLSSLLETLISKEPSYIRCIKPNDRKEPSKFDDF 600
Query: 602 RVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQS 661
++HQ++YLGL E++RVRRAG+AYRR ++ FLQRY L TWP W G +GV L++
Sbjct: 601 LIRHQIKYLGLMEHLRVRRAGFAYRRKYEHFLQRYKSLCPDTWPHWHGPPAEGVERLIKY 660
Query: 662 VNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREE 721
+ ++++LG++K+FI+ P +LF E+ E IQ ++++ + R++YV+ R+
Sbjct: 661 IGYKPEEYKLGKTKIFIRFPRTLFATEDAFEFSKHQLVARIQATYKRCLGRREYVKKRQA 720
Query: 722 ASDL-------LLNKKERRRN---SINRNFIGDYIGMEEH--PELQQFV 758
A L L K +RR I R FI +I + P+ ++F+
Sbjct: 721 AIKLEAHWRGALARKAIQRRKWAVRIIRKFIKGFISRNKPLCPDNEEFI 769
Score = 67.4 bits (163), Expect = 7e-11
Identities = 67/264 (25%), Positives = 117/264 (44%), Gaps = 25/264 (9%)
Query: 583 YIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKA 642
Y RC+ E K R ++ +K + + G ++R +A R I +KF++ + K
Sbjct: 705 YKRCLGRREYVKKR---QAAIKLEAHWRGALARKAIQRRKWAVR-IIRKFIKGFISRNKP 760
Query: 643 TWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVI 702
P EE + +N+ + K +++ P L ++ + ++
Sbjct: 761 LCPD--NEEFIVFVRKNYILNLRYHLPKTVLDKSWLRPPGILENASDLLRKMC--VRNLV 816
Query: 703 QKSWRKFVA-RKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEE-HPELQQFVGK 760
QK R A RK +Q + S++ +K+ S+N+ F+ I + +P++ Q +
Sbjct: 817 QKYCRGITAERKAMMQQKVVTSEIFRGRKDGYTESLNQPFVNSRIDEGDINPKVLQLIS- 875
Query: 761 REKIDFADTVTKYDRR-FKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIE 819
EKI + V KYDR+ FK +R L+LT K Y++ K+KQ KIE
Sbjct: 876 HEKIQYGVPVIKYDRKGFKARQRQLILTQKAAYVVELAKIKQ-------------KIEYS 922
Query: 820 RILSVSLSTMQDDIFILHEQEYDS 843
+ VS S + D I ++H DS
Sbjct: 923 ALKGVSTSNLSDGILVIHVSPEDS 946
>gi|4885503 myosin IA [Homo sapiens]
Length = 1043
Score = 581 bits (1497), Expect = e-165
Identities = 321/724 (44%), Positives = 465/724 (64%), Gaps = 33/724 (4%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
GV+D+VLL + E S+++NL+ RY + I+TYIG+V+ISVNP++Q+P +G + I YQ
Sbjct: 9 GVEDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDY 68
Query: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKV 139
YE PHIYALA+ Y+++ +QC++I+GESG+GKT A+K +MSY++ V G G +V
Sbjct: 69 TFYELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQV 128
Query: 140 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRV 199
VK+ +LQSNP+LEAFGNAKT+RNNNSSRFGKY +I+F G P GG I+N+LLEKSR+
Sbjct: 129 NSVKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRL 188
Query: 200 VMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQET 258
V + GER+FHIFYQL+ GA + +L + Y YL+ S +VD +DD F+
Sbjct: 189 VKQLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLNHEVS-RVDGMDDASSFRAV 247
Query: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNI----SFKEVGNYAA-VESEEFLAFPAYLLG 313
AM VIG EE VL++ + +L LGN+ F+ G A+ + + ++G
Sbjct: 248 QSAMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGVREIGEMVG 307
Query: 314 INQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINK 373
+N + ++ L SR M++ E + LNV QA Y RDALAK +++R+FD++V+ IN+
Sbjct: 308 LNSEEVERALCSRTMET----AKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363
Query: 374 AMEKDHEEYN--IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQE 431
+++ E +GVLDIYGFEI + N FEQF IN+ NEKLQQ+FIE+TLK EQEEY +E
Sbjct: 364 SIKVGIGEKKKVMGVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEEYKRE 423
Query: 432 GIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGS 491
GI WT ++YF+N I+C LIE+ N GI+++LD+ C V +D T L KL
Sbjct: 424 GIPWTKVDYFDNGIICKLIEH--NQRGILAMLDEECLRPGVV---SDSTFLAKLNQLFSK 478
Query: 492 HEHFNS-----------WNQG---FIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSS 537
H H+ S G F I HYAGKV+Y++ F ++N D+LF DL++ M +
Sbjct: 479 HGHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKA 538
Query: 538 ELPFIKSLFPE-NLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
+ P ++SLFPE N + RP TAG++ K L+ L +P+YIRCIKPNE ++
Sbjct: 539 QHPLLRSLFPEGNPKQASLKRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRG 598
Query: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVL 656
+ V Q YLGL EN+RVRRAGYA+R+ + FL+RY +L+++TWP W G +++GV
Sbjct: 599 QFSSDLVATQARYLGLLENVRVRRAGYAHRQGYGPFLERYRLLSRSTWPHWNGGDREGVE 658
Query: 657 HLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYV 716
+L ++M S + G++K+FI++P++LF LEE R + A +IQK +R + R Y
Sbjct: 659 KVLGELSMSSGELAFGKTKIFIRSPKTLFYLEEQRRLRLQQLATLIQKIYRGWRCRTHYQ 718
Query: 717 QMRE 720
MR+
Sbjct: 719 LMRK 722
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/193 (27%), Positives = 93/193 (48%), Gaps = 22/193 (11%)
Query: 704 KSWRKFVARKKYVQMREE--ASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKR 761
K +R ++ K+ +RE+ AS+L KK S+ F GDYIG++ +P+LQ+ G
Sbjct: 830 KRFRDQLSPKQVEILREKLCASELFKGKKASYPQSVPIPFCGDYIGLQGNPKLQKLKGGE 889
Query: 762 E-KIDFADTVTKYDR-RFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIE 819
E + A+ V K +R K R LLLT + L +K + K I ++
Sbjct: 890 EGPVLMAEAVKKVNRGNGKTSSRILLLTKGHVILTDTKKSQ-----------AKIVIGLD 938
Query: 820 RILSVSLSTMQDDIFILHEQEY-------DSLLESVFKTEFLSLLAKRYEEKTQKQLPLK 872
+ VS+++++D +F LH E D LL S E L+ + + + TQ+QL +
Sbjct: 939 NVAGVSVTSLKDGLFSLHLSEMSSVGSKGDFLLVSEHVIELLTKMYRAVLDATQRQLTVT 998
Query: 873 FSNTLELKLKKEN 885
+ ++ K+ +
Sbjct: 999 VTEKFSVRFKENS 1011
>gi|51100974 myosin ID [Homo sapiens]
Length = 1006
Score = 564 bits (1453), Expect = e-160
Identities = 308/720 (42%), Positives = 448/720 (62%), Gaps = 35/720 (4%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
G D VL+ ++ + NL+ R+ I+T+IG V++SVNP+K + +G IE Y+G
Sbjct: 10 GKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGR 69
Query: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK- 138
YE PPH++A+AD Y+ M ++ C++ISGESGAGKT A+KYIM YI+ ++ +
Sbjct: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
Query: 139 -VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKS 197
V+ VK+++L+SN +LEAFGNAKT RN+NSSRFGKY +I F G+P GG I+N+LLEKS
Sbjct: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKS 189
Query: 198 RVVMRNPGERSFHIFYQLIEGASAEQKHSLGI-TSMDYYYYLSLSGSYKVDDIDDRREFQ 256
RV+++ PGERSFH FYQL++G S + SL + S+ Y Y+ + K I+D EF+
Sbjct: 190 RVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLK-SSINDAAEFR 248
Query: 257 ETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFPAYLLGINQ 316
AM VIG EE V +I+A ILHLGN+ F G+ +E+ + ++ A LL
Sbjct: 249 VVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKT 308
Query: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAME 376
D +++ L R + + + I ++A Y RDA AKA++ R+F ++V IN +E
Sbjct: 309 DMVEKALLYRTVAT----GRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIE 364
Query: 377 KDHEEYN-------IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYV 429
+ + IGVLDIYGFEIF N FEQFCIN+ NEKLQQ+FI+L LK EQEEY
Sbjct: 365 VKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQ 424
Query: 430 QEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQI 489
+EGI W I+YFNN+I+ DL+E + GI++ILDD C VG+ D+ L+ L ++
Sbjct: 425 REGIPWKHIDYFNNQIIVDLVEQQ--HKGIIAILDDACMN---VGKVTDEMFLEALNSKL 479
Query: 490 GSHEHFNS-----------WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSE 538
G H HF+S +++ F I HYAG V Y + GF ++N+D LF D LM +S
Sbjct: 480 GKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSS 539
Query: 539 LPFIKSLFPENLQA--DKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPR 596
P +K+++PE + + RP TA + K LV L P+Y+RCIKPN+ K P+
Sbjct: 540 NPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQ 599
Query: 597 DWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQ-GEEKQGV 655
+++ R +HQVEYLGL EN+RVRRAG+A+R+ ++KFL RY ++++ TWP+ +K+ V
Sbjct: 600 IFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAV 659
Query: 656 LHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKY 715
L++ D G++K+FI+ P +LF LEE+R + +QK WR +AR +Y
Sbjct: 660 KKLIERCGF-QDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRY 718
>gi|239582755 myosin IG [Homo sapiens]
Length = 1018
Score = 531 bits (1367), Expect = e-150
Identities = 307/735 (41%), Positives = 433/735 (58%), Gaps = 45/735 (6%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
G D VLL ++T + NL+ R+ I+TYIG VL+SVNP++++P +G + I YQG
Sbjct: 10 GKPDFVLLDQVTMEDFMRNLQLRFEKGRIYTYIGEVLVSVNPYQELPLYGPEAIARYQGR 69
Query: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGG--T 137
YE PPH+YA+A+ Y+ M + C++ISGESGAGKT A+K+IM YI+ V+
Sbjct: 70 ELYERPPHLYAVANAAYKAMKHRSRDTCIVISGESGAGKTEASKHIMQYIAAVTNPSQRA 129
Query: 138 KVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKS 197
+V+ VKD++L+S +LEAFGNA+T RN+NSSRFGKY +I F G+P GG I ++LLEKS
Sbjct: 130 EVERVKDVLLKSTCVLEAFGNARTNRNHNSSRFGKYMDINFDFKGDPIGGHIHSYLLEKS 189
Query: 198 RVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGS------YKVDDIDD 251
RV+ ++ GER+FH FYQL+ G+ +Q H L + Y + G+ + D D
Sbjct: 190 RVLKQHVGERNFHAFYQLLRGSEDKQLHELHLERNPAVYNFTHQGAGLNMTVHSALD-SD 248
Query: 252 RREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYA------AVESEEFL 305
+ Q AM VIG EE V +I+A ILHLGNI F E AV E +
Sbjct: 249 EQSHQAVTEAMRVIGFSPEEVESVHRILAAILHLGNIEFVETEEGGLQKEGLAVAEEALV 308
Query: 306 AFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFD 365
A L +D + L +R + S G E I +A Y RDA AKA++ R+F+
Sbjct: 309 DHVAELTATPRDLVLRSLLARTVAS---GGRELIEKGHTAAEASYARDACAKAVYQRLFE 365
Query: 366 FLVDSINKAME-------KDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIE 418
++V+ IN ME +D ++ IGVLDIYGFE+F N FEQFCIN+ NEKLQQ+FI+
Sbjct: 366 WVVNRINSVMEPRGRDPRRDGKDTVIGVLDIYGFEVFPVNSFEQFCINYCNEKLQQLFIQ 425
Query: 419 LTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGAD 478
L LK EQEEY +EGI W +EYFNN + DL+E GI+++LD+ C+ + G D
Sbjct: 426 LILKQEQEEYEREGITWQSVEYFNNATIVDLVERPHR--GILAVLDEACS---SAGTITD 480
Query: 479 QTLLQKLQMQIGSHEHFNS-----------WNQGFIIHHYAGKVSYDMDGFCERNRDVLF 527
+ LQ L M H H+ S + + F I HYAG V+Y ++GF ++NRD LF
Sbjct: 481 RIFLQTLDMHHRHHLHYTSRQLCPTDKTMEFGRDFRIKHYAGDVTYSVEGFIDKNRDFLF 540
Query: 528 MDLIELMQSSELPFIKSLFPENLQ--ADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIR 585
D L+ +S P +++++P+ Q + RP TAG+ K LV L P Y+R
Sbjct: 541 QDFKRLLYNSTDPTLRAMWPDGQQDITEVTKRPLTAGTLFKNSMVALVENLASKEPFYVR 600
Query: 586 CIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWP 645
CIKPNE K +E+ +HQV YLGL EN+RVRRAG+A R+ + +FL RY + + TWP
Sbjct: 601 CIKPNEDKVAGKLDENHCRHQVAYLGLLENVRVRRAGFASRQPYSRFLLRYKMTCEYTWP 660
Query: 646 S-WQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQK 704
+ G +K V LL+ + D G SK+FI++P +L LE+ R R ++QK
Sbjct: 661 NHLLGSDKAAVSALLEQHGLQGD-VAFGHSKLFIRSPRTLVTLEQSRARLIPIIVLLLQK 719
Query: 705 SWRKFVARKKYVQMR 719
+WR +AR + ++R
Sbjct: 720 AWRGTLARWRCRRLR 734
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 484 bits (1246), Expect = e-136
Identities = 281/747 (37%), Positives = 434/747 (58%), Gaps = 43/747 (5%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDD-YIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78
G +D+ LS + E +++ NL+ R+ + I+TY G +L+++NP+KQ+P +G+ I Y G
Sbjct: 68 GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSG 127
Query: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138
+ PHI+A+A+ Y+ M + NQ +I+SGESGAGKTV+A+Y M Y + VS G+
Sbjct: 128 QNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSN 187
Query: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198
HV+D +L SNP+ EA GNAKT RN+NSSRFGKY EI F + G +S +LLEKSR
Sbjct: 188 A-HVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSR 246
Query: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQET 258
VV ++ ER++HIFYQL A + L + S + + Y + G+ ++ ++DR E ET
Sbjct: 247 VVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVET 306
Query: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEE--FLAFPAYLLGINQ 316
++G + Q V +I+A ILHLGN+ VGN + SE+ L LLG+
Sbjct: 307 QKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFCELLGLES 366
Query: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAME 376
R+ + L +R++ + SE++ + QA RDALAK ++A +FDF+V+ IN+A++
Sbjct: 367 GRVAQWLCNRKIVT----SSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQALQ 422
Query: 377 KDHEEYN-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRW 435
+++ IGVLDIYGFE F N FEQFCIN+ NEKLQQ F K EQEEY++E I W
Sbjct: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482
Query: 436 TPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSH--- 492
T I++++N+ V DLIE K+ GI+ +LD+ C H G D+ LQKL +
Sbjct: 483 TLIDFYDNQPVIDLIEAKM---GILELLDEECLLPH----GTDENWLQKLYNNFVNRNPL 535
Query: 493 -EHFNSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPEN-- 549
E N F+I H+A KV Y +GF E+NRD ++ L+E++++S+ + F EN
Sbjct: 536 FEKPRMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPT 595
Query: 550 -----------------LQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNET 592
++ + K TT GSK + L+ TL TPHY+RCIKPN+
Sbjct: 596 PPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDE 655
Query: 593 KKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEK 652
K P +++ R+ Q+ G+ E IR+ Y R + +F RY IL S+ ++K
Sbjct: 656 KLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSF-SDKK 714
Query: 653 QGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVAR 712
+ +L + DS+Q+Q G++K+F +A + + LE++R K ++QK R ++ R
Sbjct: 715 EVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAY-LEKLRLDKLRQSCVMVQKHMRGWLQR 773
Query: 713 KKYVQMREEASDLLLNKKERRRNSINR 739
KK+ +RE + L++ + R + ++ +
Sbjct: 774 KKF--LRERRAALIIQQYFRGQQTVRK 798
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 480 bits (1236), Expect = e-135
Identities = 268/734 (36%), Positives = 434/734 (59%), Gaps = 49/734 (6%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMD-DYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78
G +D+ LS + E +++ NLK R+++ ++I+TY G VL+++NP++Q+P +G+ I Y G
Sbjct: 70 GENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSG 129
Query: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138
+ PHI+A+A+ Y+ M D +NQ +I+SGESGAGKTV+AKY M Y + V GG
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATV-GGSAS 188
Query: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198
++++ +L S+P++EA GNAKT RN+NSSRFGKY +I F G + +LLEKSR
Sbjct: 189 ETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSR 248
Query: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQET 258
VV + ER++HIFYQL A + L +TS + ++Y S G ++ +DD +F++T
Sbjct: 249 VVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKT 308
Query: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEE-FLAFPAYLLGIN 315
A ++G+ Q + +I+A ILHLG+++ + G+ ++ ++ +L+ LLG+
Sbjct: 309 RQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRLLGVE 368
Query: 316 QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM 375
+++ L R++ + SE+ T++++Q R+ALAK ++A++F ++V+ INKA+
Sbjct: 369 HSQMEHWLCHRKLVT----TSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKAL 424
Query: 376 EKDHEEYN-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIR 434
++++ IGVLDIYGFE F+ N FEQFCIN+ NEKLQQ F K EQEEY++E I
Sbjct: 425 HTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484
Query: 435 WTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEH 494
WT I++++N+ DLIE K+ GI+ +LD+ C V +G DQ QKL + S +H
Sbjct: 485 WTLIDFYDNQPCIDLIEAKL---GILDLLDEEC----KVPKGTDQNWAQKLYDRHSSSQH 537
Query: 495 FNS---WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLFPEN-- 549
F N FII H+A KV Y DGF E+NRD ++ + I ++++S+ P + LF ++
Sbjct: 538 FQKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKD 597
Query: 550 -----------------------LQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRC 586
++ K T G + + + L+ TL TPHY+RC
Sbjct: 598 PVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRC 657
Query: 587 IKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPS 646
IKPN+ K P ++ R Q+ G+ E IR+ AGY R + F RY +L K
Sbjct: 658 IKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR--E 715
Query: 647 WQGEEKQGVLH-LLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKS 705
+K+ + +L+++ D D+FQ GR+K+F +A + + LE++R K+ +IQK+
Sbjct: 716 LANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAY-LEKLRADKFRTATIMIQKT 774
Query: 706 WRKFVARKKYVQMR 719
R ++ + KY +++
Sbjct: 775 VRGWLQKVKYHRLK 788
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 478 bits (1231), Expect = e-134
Identities = 277/744 (37%), Positives = 433/744 (58%), Gaps = 61/744 (8%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDD-YIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78
G +D+ LS + E +++ NL+ R++D I+TY G VL+++NP++Q+P +GE I Y G
Sbjct: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129
Query: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138
+ PHI+A+A+ Y+ M D NQ +I+SGESGAGKTV+AKY M Y + VSG ++
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189
Query: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198
+V++ +L SNP++E+ GNAKT RN+NSSRFGKY EI F G + +LLEKSR
Sbjct: 190 A-NVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248
Query: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQET 258
VV + ER++HIFYQL A + L + + D + Y GS ++ +DD +E T
Sbjct: 249 VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHT 308
Query: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEEFLAFPAYLLGINQ 316
A ++GI Q + +I+AGILHLGN+ F ++ + E L L+G++
Sbjct: 309 RQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMGVDY 368
Query: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAME 376
+ + L R++ + +E+ ++ QA RDALAK ++A++F+++VD++N+A+
Sbjct: 369 EEMCHWLCHRKLAT----ATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
Query: 377 KDHEEYN-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRW 435
++++ IGVLDIYGFE F+ N FEQFCIN+ NEKLQQ F K EQEEY++E I W
Sbjct: 425 SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPW 484
Query: 436 TPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHF 495
T I++++N+ +LIE+K+ GI+ +LD+ C + +G D T QKL + H
Sbjct: 485 TLIDFYDNQPCINLIESKL---GILDLLDEEC----KMPKGTDDTWAQKLY-----NTHL 532
Query: 496 NSW---------NQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLF 546
N N+ FII H+A KV Y +GF E+N+D +F + I++++SS+ + LF
Sbjct: 533 NKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELF 592
Query: 547 PENLQA--------------------DKKGRP--------TTAGSKIKKQANDLVSTLMK 578
++ +A KGRP T G + + + L+ TL
Sbjct: 593 QDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNA 652
Query: 579 CTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAI 638
TPHY+RCIKPN+ K P ++E R Q+ G+ E IR+ AG+ R +Q+F RY +
Sbjct: 653 TTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRV 712
Query: 639 LTKATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGY 698
L K + KQ ++L+ + +D D++Q G++K+F +A + + LE++R K
Sbjct: 713 LMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRADKLRAA 769
Query: 699 ARVIQKSWRKFVARKKYVQMREEA 722
IQK+ R ++ RKKY++MR+ A
Sbjct: 770 CIRIQKTIRGWLLRKKYLRMRKAA 793
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 478 bits (1231), Expect = e-134
Identities = 277/744 (37%), Positives = 433/744 (58%), Gaps = 61/744 (8%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDD-YIFTYIGSVLISVNPFKQMPYFGEKEIEMYQG 78
G +D+ LS + E +++ NL+ R++D I+TY G VL+++NP++Q+P +GE I Y G
Sbjct: 70 GENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSG 129
Query: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTK 138
+ PHI+A+A+ Y+ M D NQ +I+SGESGAGKTV+AKY M Y + VSG ++
Sbjct: 130 QNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASE 189
Query: 139 VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSR 198
+V++ +L SNP++E+ GNAKT RN+NSSRFGKY EI F G + +LLEKSR
Sbjct: 190 A-NVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSR 248
Query: 199 VVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQET 258
VV + ER++HIFYQL A + L + + D + Y GS ++ +DD +E T
Sbjct: 249 VVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHT 308
Query: 259 LHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEEFLAFPAYLLGINQ 316
A ++GI Q + +I+AGILHLGN+ F ++ + E L L+G++
Sbjct: 309 RQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLMGVDY 368
Query: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAME 376
+ + L R++ + +E+ ++ QA RDALAK ++A++F+++VD++N+A+
Sbjct: 369 EEMCHWLCHRKLAT----ATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
Query: 377 KDHEEYN-IGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRW 435
++++ IGVLDIYGFE F+ N FEQFCIN+ NEKLQQ F K EQEEY++E I W
Sbjct: 425 SAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIPW 484
Query: 436 TPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHF 495
T I++++N+ +LIE+K+ GI+ +LD+ C + +G D T QKL + H
Sbjct: 485 TLIDFYDNQPCINLIESKL---GILDLLDEEC----KMPKGTDDTWAQKLY-----NTHL 532
Query: 496 NSW---------NQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLF 546
N N+ FII H+A KV Y +GF E+N+D +F + I++++SS+ + LF
Sbjct: 533 NKCALFEKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELF 592
Query: 547 PENLQA--------------------DKKGRP--------TTAGSKIKKQANDLVSTLMK 578
++ +A KGRP T G + + + L+ TL
Sbjct: 593 QDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNA 652
Query: 579 CTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAI 638
TPHY+RCIKPN+ K P ++E R Q+ G+ E IR+ AG+ R +Q+F RY +
Sbjct: 653 TTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRV 712
Query: 639 LTKATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGY 698
L K + KQ ++L+ + +D D++Q G++K+F +A + + LE++R K
Sbjct: 713 LMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAY-LEKLRADKLRAA 769
Query: 699 ARVIQKSWRKFVARKKYVQMREEA 722
IQK+ R ++ RKKY++MR+ A
Sbjct: 770 CIRIQKTIRGWLLRKKYLRMRKAA 793
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 474 bits (1221), Expect = e-133
Identities = 316/890 (35%), Positives = 490/890 (55%), Gaps = 70/890 (7%)
Query: 14 HNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKE- 72
H GVDDM L+++ SI+ NL +RY + I+TYIGS+L SVNP++ + E
Sbjct: 58 HPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPAT 117
Query: 73 IEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRV 132
+E Y E PPHI+A+A+ YR + +NQC++ISGESGAGKT + K I+ ++S +
Sbjct: 118 MEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVI 177
Query: 133 SGGGT------KVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDG 186
S K V+ IL+S+P++EAFGNAKTV NNNSSRFGK+ ++ G G
Sbjct: 178 SQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQG 237
Query: 187 GKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKV 246
G+I ++LLEK+RVV +NPGER++HIFY L+ G E++ +++ + Y+YL+ SG +
Sbjct: 238 GRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVED 297
Query: 247 DDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLA 306
I D+ F+E + AM+V+ EE V +++AGILHLGNI F G A V + L
Sbjct: 298 KTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGG-AQVSFKTALG 356
Query: 307 FPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDF 366
A LLG++ +L + LT R M + E I LNV+QA +RD+LA AL+A F++
Sbjct: 357 RSAELLGLDPTQLTDALTQRSMFL----RGEEILTPLNVQQAVDSRDSLAMALYACCFEW 412
Query: 367 LVDSINKAMEKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQE 426
++ IN ++ + + +IG+LDI+GFE F+ N FEQF IN+ NEKLQ+ F + EQ
Sbjct: 413 VIKKINSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQL 472
Query: 427 EYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQ 486
EY +EG+ W I++ +N DLIE K+ G+++++++ A D TLL+KL
Sbjct: 473 EYSREGLVWEDIDWIDNGECLDLIEKKL---GLLALINEESHFPQA----TDSTLLEKLH 525
Query: 487 MQIGSHEHFNSWN---QGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIK 543
Q ++ + F + HYAG+V YD+ G E+NRD DL+ L++ S FI
Sbjct: 526 SQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIY 585
Query: 544 SLF--------PENLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKP 595
LF + L+ K R T S+ K + L++TL P ++RCIKPN K P
Sbjct: 586 DLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMP 645
Query: 596 RDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGV 655
++++ V +Q+ Y G+ E +R+R+AGYA RR FQ F +RY +L + + + +
Sbjct: 646 DQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL--ALPEDVRGKC 703
Query: 656 LHLLQSVNMDSDQFQLGRSKVFIKAPESL-FLLEEMRERKYDGYARVIQKSWRKFVARKK 714
LLQ + + ++QLG++KVF++ ESL LE+ RE + A VI+ F+ARK+
Sbjct: 704 TSLLQLYDASNSEWQLGKTKVFLR--ESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQ 761
Query: 715 YVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGKREKIDFADTVTKYD 774
Y R+ +++ +K R + R F+ L++ +K +
Sbjct: 762 Y---RKVLYCVVIIQKNYRAFLLRRRFL----------HLKKAAIVFQKQLRGQIARRVY 808
Query: 775 RRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEIERILSVSLSTMQDDIF 834
R+ KR+ EK KQ ++ +E +R+ E ER L Q++
Sbjct: 809 RQLLAEKRE-----------QEEKKKQEEEEKKKREEEERERERER-REAELRAQQEE-E 855
Query: 835 ILHEQEYDSLLESVFKTEFLSLLAKRYEEKTQKQLPLKFSNTLELKLKKE 884
+QE ++L +S + E L K+ E K +++ L+L+KE
Sbjct: 856 TRKQQELEALQKSQKEAELTRELEKQKENKQVEEI---------LRLEKE 896
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 474 bits (1220), Expect = e-133
Identities = 281/748 (37%), Positives = 428/748 (57%), Gaps = 40/748 (5%)
Query: 14 HNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEI 73
H GV+DM+ L + E I+ NL RY D I+TY GS+L++VNP++ + + + I
Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119
Query: 74 EMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVS 133
Y E PPHI+A+ADN Y NM + +QC IISGESGAGKT + K I+ +++ +S
Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 134 GGGTKVQH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISN 191
G QH ++ +L++ P+LEAFGNAKT+RN+NSSRFGKY +I F+ G +G KI
Sbjct: 180 G-----QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQ 234
Query: 192 FLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDD 251
+LLEKSRV + ER++H+FY ++EG S +QK LG+ Y YL++ + D
Sbjct: 235 YLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD 294
Query: 252 RREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFP--- 308
+E+ AM V+ E + +++A ILHLGN+ + E + +++ E L P
Sbjct: 295 SQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY-EARTFENLDACEVLFSPSLA 353
Query: 309 --AYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDF 366
A LL +N L LTSR + + + E++ L+ EQA RDA K ++ R+F +
Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLIT----RGETVSTPLSREQALDVRDAFVKGIYGRLFVW 409
Query: 367 LVDSINKAMEK------DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 420
+VD IN A+ K + +IG+LDI+GFE F N FEQ CINF NE LQQ F+
Sbjct: 410 IVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469
Query: 421 LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT 480
K EQEEY E I W IE+ +N+ D+I NK P I+S++D+ +G D T
Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANK--PMNIISLIDE----ESKFPKGTDTT 523
Query: 481 LLQKLQMQIGSHEHF----NSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQS 536
+L KL Q + ++ N+ F I+H+AG V Y+ GF E+NRD L D+I+L+ S
Sbjct: 524 MLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHS 583
Query: 537 SELPFIKSLFPEN--LQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKK 594
S FIK +F + + A+ + R T S+ K+ L+ TL C P ++RCIKPNE KK
Sbjct: 584 SRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK 643
Query: 595 PRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSW-QGEEKQ 653
P ++ Q+ Y G+ E IR+RRAGY R F +F++RY +L P++ QG+ +
Sbjct: 644 PMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRG 703
Query: 654 GVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARK 713
+ ++V D +Q+G++K+F+K + LLE R++ ++QK R F R
Sbjct: 704 TCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM-LLEVERDKAITDRVILLQKVIRGFKDRS 762
Query: 714 KYVQMREEASDLLLNKKERRRNSINRNF 741
+++++ A+ L ++ R ++ +N+
Sbjct: 763 NFLKLKNAAT---LIQRHWRGHNCRKNY 787
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 474 bits (1220), Expect = e-133
Identities = 281/748 (37%), Positives = 428/748 (57%), Gaps = 40/748 (5%)
Query: 14 HNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEI 73
H GV+DM+ L + E I+ NL RY D I+TY GS+L++VNP++ + + + I
Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119
Query: 74 EMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVS 133
Y E PPHI+A+ADN Y NM + +QC IISGESGAGKT + K I+ +++ +S
Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 134 GGGTKVQH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISN 191
G QH ++ +L++ P+LEAFGNAKT+RN+NSSRFGKY +I F+ G +G KI
Sbjct: 180 G-----QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQ 234
Query: 192 FLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDD 251
+LLEKSRV + ER++H+FY ++EG S +QK LG+ Y YL++ + D
Sbjct: 235 YLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD 294
Query: 252 RREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFP--- 308
+E+ AM V+ E + +++A ILHLGN+ + E + +++ E L P
Sbjct: 295 SQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY-EARTFENLDACEVLFSPSLA 353
Query: 309 --AYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDF 366
A LL +N L LTSR + + + E++ L+ EQA RDA K ++ R+F +
Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLIT----RGETVSTPLSREQALDVRDAFVKGIYGRLFVW 409
Query: 367 LVDSINKAMEK------DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 420
+VD IN A+ K + +IG+LDI+GFE F N FEQ CINF NE LQQ F+
Sbjct: 410 IVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469
Query: 421 LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT 480
K EQEEY E I W IE+ +N+ D+I NK P I+S++D+ +G D T
Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANK--PMNIISLIDE----ESKFPKGTDTT 523
Query: 481 LLQKLQMQIGSHEHF----NSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQS 536
+L KL Q + ++ N+ F I+H+AG V Y+ GF E+NRD L D+I+L+ S
Sbjct: 524 MLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHS 583
Query: 537 SELPFIKSLFPEN--LQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKK 594
S FIK +F + + A+ + R T S+ K+ L+ TL C P ++RCIKPNE KK
Sbjct: 584 SRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK 643
Query: 595 PRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSW-QGEEKQ 653
P ++ Q+ Y G+ E IR+RRAGY R F +F++RY +L P++ QG+ +
Sbjct: 644 PMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRG 703
Query: 654 GVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARK 713
+ ++V D +Q+G++K+F+K + LLE R++ ++QK R F R
Sbjct: 704 TCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM-LLEVERDKAITDRVILLQKVIRGFKDRS 762
Query: 714 KYVQMREEASDLLLNKKERRRNSINRNF 741
+++++ A+ L ++ R ++ +N+
Sbjct: 763 NFLKLKNAAT---LIQRHWRGHNCRKNY 787
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 474 bits (1220), Expect = e-133
Identities = 281/748 (37%), Positives = 428/748 (57%), Gaps = 40/748 (5%)
Query: 14 HNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEI 73
H GV+DM+ L + E I+ NL RY D I+TY GS+L++VNP++ + + + I
Sbjct: 60 HPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHI 119
Query: 74 EMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVS 133
Y E PPHI+A+ADN Y NM + +QC IISGESGAGKT + K I+ +++ +S
Sbjct: 120 RQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS 179
Query: 134 GGGTKVQH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISN 191
G QH ++ +L++ P+LEAFGNAKT+RN+NSSRFGKY +I F+ G +G KI
Sbjct: 180 G-----QHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQ 234
Query: 192 FLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDD 251
+LLEKSRV + ER++H+FY ++EG S +QK LG+ Y YL++ + D
Sbjct: 235 YLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD 294
Query: 252 RREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESEEFLAFP--- 308
+E+ AM V+ E + +++A ILHLGN+ + E + +++ E L P
Sbjct: 295 SQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQY-EARTFENLDACEVLFSPSLA 353
Query: 309 --AYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDF 366
A LL +N L LTSR + + + E++ L+ EQA RDA K ++ R+F +
Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLIT----RGETVSTPLSREQALDVRDAFVKGIYGRLFVW 409
Query: 367 LVDSINKAMEK------DHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 420
+VD IN A+ K + +IG+LDI+GFE F N FEQ CINF NE LQQ F+
Sbjct: 410 IVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHV 469
Query: 421 LKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQT 480
K EQEEY E I W IE+ +N+ D+I NK P I+S++D+ +G D T
Sbjct: 470 FKLEQEEYDLESIDWLHIEFTDNQDALDMIANK--PMNIISLIDE----ESKFPKGTDTT 523
Query: 481 LLQKLQMQIGSHEHF----NSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQS 536
+L KL Q + ++ N+ F I+H+AG V Y+ GF E+NRD L D+I+L+ S
Sbjct: 524 MLHKLNSQHKLNANYIPPKNNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHS 583
Query: 537 SELPFIKSLFPEN--LQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKK 594
S FIK +F + + A+ + R T S+ K+ L+ TL C P ++RCIKPNE KK
Sbjct: 584 SRNKFIKQIFQADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK 643
Query: 595 PRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSW-QGEEKQ 653
P ++ Q+ Y G+ E IR+RRAGY R F +F++RY +L P++ QG+ +
Sbjct: 644 PMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRG 703
Query: 654 GVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARK 713
+ ++V D +Q+G++K+F+K + LLE R++ ++QK R F R
Sbjct: 704 TCQRMAEAVLGTHDDWQIGKTKIFLKDHHDM-LLEVERDKAITDRVILLQKVIRGFKDRS 762
Query: 714 KYVQMREEASDLLLNKKERRRNSINRNF 741
+++++ A+ L ++ R ++ +N+
Sbjct: 763 NFLKLKNAAT---LIQRHWRGHNCRKNY 787
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 462 bits (1188), Expect = e-129
Identities = 272/744 (36%), Positives = 417/744 (56%), Gaps = 54/744 (7%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
GVDDM+ L + E +V NL RY I+TY GS+L++VNPF+ +P + +++++Y
Sbjct: 66 GVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQLYYSR 125
Query: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKV 139
E PPH++A+A+N Y +M ++ +QC IISGESGAGKT K I+ +++ +SG
Sbjct: 126 HMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISG----- 180
Query: 140 QH--VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKS 197
QH ++ +L++NP+LEAFGNAKT+RN+NSSRFGKY +I F+P G +G +I FLLEKS
Sbjct: 181 QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLEKS 240
Query: 198 RVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQE 257
RV + P ER++HIFY ++ G SAE K L + + Y+YL++ + ++D +++
Sbjct: 241 RVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDYAH 300
Query: 258 TLHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVESEEFLAFPAY--LLG 313
AM ++ E V++++A ILHLGN+ F N A + E AFP LL
Sbjct: 301 IRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKLLE 360
Query: 314 INQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINK 373
+ L++ L + + E + +LN+ QA RDA K ++ +F ++V IN
Sbjct: 361 VQHQELRDCLIKHTILI----RGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINA 416
Query: 374 AM------EKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEE 427
A+ + + IG+LDI+GFE F+ N FEQ CINF NE LQQ F++ EQEE
Sbjct: 417 AIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEE 476
Query: 428 YVQEGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQM 487
Y E I W I Y +N+ DL+ K P I+S+LD+ +G D T+LQKL
Sbjct: 477 YRSENISWDYIHYTDNRPTLDLLALK--PMSIISLLDE----ESRFPQGTDLTMLQKLNS 530
Query: 488 QIGSHEHF----NSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIK 543
+++ F N + F I H+AG+V Y +GF E+NRDVL D++ L+ SS+ F++
Sbjct: 531 VHANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLR 590
Query: 544 SLFPENL---------------------QADKKGRPTTAGSKIKKQANDLVSTLMKCTPH 582
+F L AD RP+T GS+ K+ + L+ L C P+
Sbjct: 591 EIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPY 650
Query: 583 YIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAI-LTK 641
+IRCIKPNE KKP ++ Q+ Y G+ E + +R++G+ R F++F QR+ + L
Sbjct: 651 FIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPN 710
Query: 642 ATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARV 701
A QG+ +Q L + ++ G++K+F++ + LLE R + D A
Sbjct: 711 AMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDT-LLEVQRSQVLDRAALS 769
Query: 702 IQKSWRKFVARKKYVQMREEASDL 725
IQK R + RK++++ R A L
Sbjct: 770 IQKVLRGYRYRKEFLRQRRAAVTL 793
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 454 bits (1167), Expect = e-127
Identities = 277/738 (37%), Positives = 415/738 (56%), Gaps = 44/738 (5%)
Query: 17 KHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMY 76
K S V+DM L+ + E S++ NLK+RY I+TY G + +NP+K +P + E+ +EMY
Sbjct: 79 KFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMY 138
Query: 77 QGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGG 136
+G ++E PPHIYA+ D YR+M+ DRE+Q ++ +GESGAGKT K ++ Y++ V+
Sbjct: 139 KGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSH 198
Query: 137 TKVQHVKDI---ILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFL 193
+ ++ +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G G I +L
Sbjct: 199 KSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYL 258
Query: 194 LEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRR 253
LEKSR + + ER+FHIFY L+ GA K L + + Y +LS +G + D+
Sbjct: 259 LEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLS-NGHVTIPGQQDKD 317
Query: 254 EFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGN--YAAVESEEFLAFPAYL 311
FQET+ AM ++GI EEQ +L++++G+L LGNI FK+ N A++ ++L
Sbjct: 318 MFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHL 377
Query: 312 LGIN-QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDS 370
LGIN D + LT R + + + EQA + +ALAKA + R+F +LV
Sbjct: 378 LGINVTDFTRGILTPRIKVGR-----DYVQKAQTKEQADFAIEALAKATYERMFRWLVLR 432
Query: 371 INKAMEKDHEE--YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEY 428
INKA++K + IG+LDI GFEIF N FEQ CIN+ NEKLQQ+F EQEEY
Sbjct: 433 INKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 492
Query: 429 VQEGIRWTPIEYFNNKIVC-DLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQM 487
+EGI W I++ + C DLIE PPGI+++LD+ C A D++ ++K+
Sbjct: 493 QREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKA----TDKSFVEKVMQ 548
Query: 488 QIGSHEHFNSWNQ-----GFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFI 542
+ G+H F Q F I HYAGKV Y D + +N D L ++ L+ S F+
Sbjct: 549 EQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFV 608
Query: 543 KSLFPE-------------------NLQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHY 583
L+ + +KG T G K+Q L++TL P++
Sbjct: 609 SELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNF 668
Query: 584 IRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKAT 643
+RCI PN KK + V Q+ G+ E IR+ R G+ R +FQ+F QRY ILT +
Sbjct: 669 VRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNS 728
Query: 644 WPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQ 703
P + KQ + +++++ +DS+ +++G+SKVF +A L LEE R+ K Q
Sbjct: 729 IPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRA-GVLAHLEEERDLKITDVIIGFQ 787
Query: 704 KSWRKFVARKKYVQMREE 721
R ++ARK + + +++
Sbjct: 788 ACCRGYLARKAFAKRQQQ 805
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 452 bits (1164), Expect = e-127
Identities = 293/864 (33%), Positives = 466/864 (53%), Gaps = 58/864 (6%)
Query: 17 KHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMY 76
K S V+DM L+ + E S++ NL++RY I+TY G + VNP+K +P + EK ++MY
Sbjct: 83 KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142
Query: 77 QGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGG- 135
+G ++E PPHIYA+AD YR+M+ DRE+Q ++ +GESGAGKT K ++ Y++ V+
Sbjct: 143 KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202
Query: 136 -GTK----VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKIS 190
G K ++ +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G G I
Sbjct: 203 KGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
Query: 191 NFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDID 250
+LLEKSR + + ER+FHIFY +I GA + + L + + Y +LS +G +
Sbjct: 263 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQ 321
Query: 251 DRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGN--YAAVESEEFLAFP 308
D FQET+ AM ++G EEQ +L++V+ +L LGNI FK+ N A++
Sbjct: 322 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 381
Query: 309 AYLLGIN-QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFL 367
+L+GIN D + LT R + + + EQA + +ALAKA + R+F ++
Sbjct: 382 CHLMGINVTDFTRSILTPRIKVGR-----DVVQKAQTKEQADFAVEALAKATYERLFRWI 436
Query: 368 VDSINKAMEKDHEE--YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQ 425
+ +NKA++K H + +G+LDI GFEIF+ N FEQ CIN+ NEKLQQ+F EQ
Sbjct: 437 LTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQ 496
Query: 426 EEYVQEGIRWTPIEYFNNKIVC-DLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQK 484
EEY +EGI W I++ + C +LIE NPPG++++LD+ C A D++ ++K
Sbjct: 497 EEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKA----TDKSFVEK 552
Query: 485 LQMQIGSHEHFNSWNQ-----GFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSEL 539
L + GSH F Q F I HYAGKV Y+ + +N D L ++ L+ +S
Sbjct: 553 LCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSD 612
Query: 540 PFIKSLFPE-------------------NLQADKKGRPTTAGSKIKKQANDLVSTLMKCT 580
F+ L+ + + KKG T G K+Q L++TL T
Sbjct: 613 KFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTT 672
Query: 581 PHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILT 640
P+++RCI PN K+ + V Q+ G+ E IR+ R G+ R +FQ+F QRY IL
Sbjct: 673 PNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILA 732
Query: 641 KATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYAR 700
P + KQ + +++++ +D + +++G+SK+F + L LEE R+ K
Sbjct: 733 ANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDVIM 791
Query: 701 VIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGK 760
Q R ++ARK + + +++ + + + ++ RN+ + + P LQ +
Sbjct: 792 AFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQE 851
Query: 761 REKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEI-- 818
E D + K R + + + L + ++ + +K L++E L+ + E+
Sbjct: 852 EEMQAKEDELQKTKERQQKAENE-------LKELEQKHSQLTEEKNLLQEQLQAETELYA 904
Query: 819 -ERILSVSLSTMQDDI-FILHEQE 840
+ V L+ + ++ ILHE E
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEME 928
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 452 bits (1164), Expect = e-127
Identities = 293/864 (33%), Positives = 466/864 (53%), Gaps = 58/864 (6%)
Query: 17 KHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMY 76
K S V+DM L+ + E S++ NL++RY I+TY G + VNP+K +P + EK ++MY
Sbjct: 83 KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142
Query: 77 QGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGG- 135
+G ++E PPHIYA+AD YR+M+ DRE+Q ++ +GESGAGKT K ++ Y++ V+
Sbjct: 143 KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202
Query: 136 -GTK----VQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKIS 190
G K ++ +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G G I
Sbjct: 203 KGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
Query: 191 NFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDID 250
+LLEKSR + + ER+FHIFY +I GA + + L + + Y +LS +G +
Sbjct: 263 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQ 321
Query: 251 DRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGN--YAAVESEEFLAFP 308
D FQET+ AM ++G EEQ +L++V+ +L LGNI FK+ N A++
Sbjct: 322 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 381
Query: 309 AYLLGIN-QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFL 367
+L+GIN D + LT R + + + EQA + +ALAKA + R+F ++
Sbjct: 382 CHLMGINVTDFTRSILTPRIKVGR-----DVVQKAQTKEQADFAVEALAKATYERLFRWI 436
Query: 368 VDSINKAMEKDHEE--YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQ 425
+ +NKA++K H + +G+LDI GFEIF+ N FEQ CIN+ NEKLQQ+F EQ
Sbjct: 437 LTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQ 496
Query: 426 EEYVQEGIRWTPIEYFNNKIVC-DLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQK 484
EEY +EGI W I++ + C +LIE NPPG++++LD+ C A D++ ++K
Sbjct: 497 EEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKA----TDKSFVEK 552
Query: 485 LQMQIGSHEHFNSWNQ-----GFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSEL 539
L + GSH F Q F I HYAGKV Y+ + +N D L ++ L+ +S
Sbjct: 553 LCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSD 612
Query: 540 PFIKSLFPE-------------------NLQADKKGRPTTAGSKIKKQANDLVSTLMKCT 580
F+ L+ + + KKG T G K+Q L++TL T
Sbjct: 613 KFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTT 672
Query: 581 PHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILT 640
P+++RCI PN K+ + V Q+ G+ E IR+ R G+ R +FQ+F QRY IL
Sbjct: 673 PNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILA 732
Query: 641 KATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYAR 700
P + KQ + +++++ +D + +++G+SK+F + L LEE R+ K
Sbjct: 733 ANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDLKITDVIM 791
Query: 701 VIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPELQQFVGK 760
Q R ++ARK + + +++ + + + ++ RN+ + + P LQ +
Sbjct: 792 AFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQE 851
Query: 761 REKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLKRKIEI-- 818
E D + K R + + + L + ++ + +K L++E L+ + E+
Sbjct: 852 EEMQAKEDELQKTKERQQKAENE-------LKELEQKHSQLTEEKNLLQEQLQAETELYA 904
Query: 819 -ERILSVSLSTMQDDI-FILHEQE 840
+ V L+ + ++ ILHE E
Sbjct: 905 EAEEMRVRLAAKKQELEEILHEME 928
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 451 bits (1161), Expect = e-126
Identities = 285/748 (38%), Positives = 412/748 (55%), Gaps = 44/748 (5%)
Query: 12 QSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEK 71
Q + K ++DM +L+ + E +++ NLK RY I+TY G ++VNP+K +P + +
Sbjct: 78 QQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPE 137
Query: 72 EIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISR 131
+ Y+G + E PPHI++++DN Y+ M+ DRENQ ++I+GESGAGKTV K ++ Y +
Sbjct: 138 VVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAV 197
Query: 132 VSGGGTKVQH--------VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGE 183
++ G + + ++D I+Q+NP LEAFGNAKTVRN+NSSRFGK+ I F G+
Sbjct: 198 IAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGK 257
Query: 184 PDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGS 243
I +LLEKSRV+ + ER +HIFYQ++ E L IT+ Y Y G
Sbjct: 258 LASADIETYLLEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGE 317
Query: 244 YKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISF--KEVGNYAAVES 301
V IDD E T +A +V+G +EE+ + ++ I+H GN+ F K+ A +
Sbjct: 318 TTVASIDDAEELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDG 377
Query: 302 EEFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHA 361
E AYL+G+N L + L ++ K G +E + NV+Q Y ALAKA++
Sbjct: 378 TEEADKSAYLMGLNSADLLKGLCHPRV--KVG--NEYVTKGQNVQQVIYATGALAKAVYE 433
Query: 362 RVFDFLVDSINKAME-KDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELT 420
R+F+++V IN +E K +Y IGVLDI GFEIF N FEQ CINF NEKLQQ F
Sbjct: 434 RMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHM 493
Query: 421 LKAEQEEYVQEGIRWTPIEYFNNKIVC-DLIENKVNPPGIMSILDDVCATMHAVGEGADQ 479
EQEEY +EGI WT I++ + C DLIE P GIMSIL++ C A D
Sbjct: 494 FVLEQEEYKKEGIEWTFIDFGMDLQACIDLIE---KPMGIMSILEEECMFPKA----TDM 546
Query: 480 TLLQKL-QMQIGSHEHFNSWNQ-------GFIIHHYAGKVSYDMDGFCERNRDVLFMDLI 531
T KL +G +F F + HYAG V Y++ G+ ++N+D L ++
Sbjct: 547 TFKAKLFDNHLGKSANFQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVV 606
Query: 532 ELMQSSELPFIKSLFPENLQAD----------KKGRP-TTAGSKIKKQANDLVSTLMKCT 580
L Q S L + +LF AD KKG T + ++ N L++ L
Sbjct: 607 GLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTH 666
Query: 581 PHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILT 640
PH++RCI PNETK P + V HQ+ G+ E IR+ R G+ R ++ F QRY IL
Sbjct: 667 PHFVRCIIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 726
Query: 641 KATWPSWQG-EEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYA 699
A P Q + ++G LL S+++D +Q++ G +KVF KA L LLEEMR+ +
Sbjct: 727 PAAIPEGQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKA-GLLGLLEEMRDERLSRII 785
Query: 700 RVIQKSWRKFVARKKYVQMREEASDLLL 727
IQ R +AR +Y ++ E LL+
Sbjct: 786 TRIQAQSRGVLARMEYKKLLERRDSLLV 813
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 451 bits (1161), Expect = e-126
Identities = 276/744 (37%), Positives = 415/744 (55%), Gaps = 45/744 (6%)
Query: 17 KHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMY 76
K S V+DM L+ + E S++ NLK RY I+TY G + +NP+K +P + E IEMY
Sbjct: 83 KFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMY 142
Query: 77 QGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGG- 135
+G ++E PPHIYA++++ YR M+ DRE+Q ++ +GESGAGKT K ++ Y++ V+
Sbjct: 143 RGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSH 202
Query: 136 -GTKVQHV----KDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKIS 190
G K ++ + +LQ+NP+LE+FGNAKTV+N+NSSRFGK+ I F G G I
Sbjct: 203 KGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 262
Query: 191 NFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDID 250
+LLEKSR V + ER+FHIFYQL+ GA K L + + Y +LS +G +
Sbjct: 263 TYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLS-NGYIPIPGQQ 321
Query: 251 DRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGN--YAAVESEEFLAFP 308
D+ FQET+ AM+++G EE +L++V+ +L GNISFK+ N A++
Sbjct: 322 DKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKL 381
Query: 309 AYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLV 368
+LLG+N + + ++ K G + + EQA + +ALAKA + R+F +LV
Sbjct: 382 CHLLGMNVMEFTRAILTPRI--KVG--RDYVQKAQTKEQADFAVEALAKATYERLFRWLV 437
Query: 369 DSINKAMEKDHEE--YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQE 426
INKA+++ + IG+LDI GFEIF+ N FEQ CIN+ NEKLQQ+F EQE
Sbjct: 438 HRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQE 497
Query: 427 EYVQEGIRWTPIEYFNNKIVC-DLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKL 485
EY +EGI W I++ + C DLIE NPPG++++LD+ C A D+T ++KL
Sbjct: 498 EYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKA----TDKTFVEKL 553
Query: 486 QMQIGSHEHFNSWNQ-----GFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELP 540
+ GSH F Q F I HYAGKV Y D + +N D L ++ L+ S
Sbjct: 554 VQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDR 613
Query: 541 FIKSLFPE-------------------NLQADKKGRPTTAGSKIKKQANDLVSTLMKCTP 581
F+ L+ + + KKG T G K+ L++TL P
Sbjct: 614 FVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNP 673
Query: 582 HYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTK 641
+++RCI PN K+ + V Q+ G+ E IR+ R G+ R +FQ+F QRY ILT
Sbjct: 674 NFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTP 733
Query: 642 ATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARV 701
P + KQ +++++ +D + +++G+SK+F +A L LEE R+ K
Sbjct: 734 NAIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRA-GVLAHLEEERDLKITDIIIF 792
Query: 702 IQKSWRKFVARKKYVQMREEASDL 725
Q R ++ARK + + +++ S L
Sbjct: 793 FQAVCRGYLARKAFAKKQQQLSAL 816
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 451 bits (1160), Expect = e-126
Identities = 270/735 (36%), Positives = 421/735 (57%), Gaps = 42/735 (5%)
Query: 20 GVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGA 79
GV+DM L + E +++ NLK R+ + I+TYIGS+L+SVNP++ +G ++++ Y G
Sbjct: 1223 GVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGR 1282
Query: 80 AQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKV 139
A ENPPH++A+A+ + M+ ++NQC+IISGESG+GKT A K I+ Y++ ++ +
Sbjct: 1283 ALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVM 1342
Query: 140 QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRV 199
Q +K IL++ PLLE+FGNAKTVRN+NSSRFGK+ EI F GG G S +LLEKSR+
Sbjct: 1343 QQIK--ILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRI 1399
Query: 200 VMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDDRREFQETL 259
V + ER++HIFY+L+ G A+ + + + + YYYL+ G+ ++ D +F+ L
Sbjct: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLL 1459
Query: 260 HAMNVIGIFAEEQTLVLQIVAGILHLGNISFK----EVGNYAAVESEEFLAFPAYLLGIN 315
AM V+G +E+Q + +I+A ILHLGN+ F+ + A+V S + A LL I+
Sbjct: 1460 AAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQIS 1519
Query: 316 QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM 375
+ L++ +T + ++ E I L VE A RDA+AK L+A +F +L+ +N +
Sbjct: 1520 PEGLQKAITFKVTET----MREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV 1575
Query: 376 EKDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRW 435
+ +I +LDIYGFE N FEQ CIN+ NE LQ +F ++ + EQEEY++E I W
Sbjct: 1576 SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDW 1635
Query: 436 TPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIGSHEHF 495
I + +N+ +LI K P GI+ ILDD C A D T LQK G++ +
Sbjct: 1636 QEITFADNQPCINLISLK--PYGILRILDDQCCFPQA----TDHTFLQKCHYHHGANPLY 1689
Query: 496 NSWNQ---GFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSLF------ 546
+ F I HYAGKV+Y + F ++N D + D+++L S + LF
Sbjct: 1690 SKPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQ 1749
Query: 547 --PENL----QADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEE 600
P+ L + + T +K ++ DLV + +C P ++RC+KPN K+P +E
Sbjct: 1750 AAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEP 1809
Query: 601 SRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILT--KATWPSWQGEEKQGVLHL 658
V Q+ Y G+ E +R+R+ G+ R FQ F+ RY L K P+ G+ VL
Sbjct: 1810 DVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLVALKHDLPA-NGDMCVSVLSR 1868
Query: 659 LQSVNMDSDQFQLGRSKVFIKAPESLF-LLEEMRERKYDGYARVIQKSWRKFVARKKYVQ 717
L V + +++G SK+F+K E L+ LLE MRE + A +Q+ R F ++++
Sbjct: 1869 LCKVM--PNMYRVGVSKLFLK--EHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRS 1924
Query: 718 MREEASDLLLNKKER 732
+R + +LL + R
Sbjct: 1925 LRHKI--ILLQSRAR 1937
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 450 bits (1158), Expect = e-126
Identities = 292/871 (33%), Positives = 465/871 (53%), Gaps = 65/871 (7%)
Query: 17 KHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMY 76
K S V+DM L+ + E S++ NL++RY I+TY G + VNP+K +P + EK ++MY
Sbjct: 83 KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142
Query: 77 QGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVS--- 133
+G ++E PPHIYA+AD YR+M+ DRE+Q ++ +GESGAGKT K ++ Y++ V+
Sbjct: 143 KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202
Query: 134 ----------GGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGE 183
G ++ +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G
Sbjct: 203 KGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGY 262
Query: 184 PDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGS 243
G I +LLEKSR + + ER+FHIFY +I GA + + L + + Y +LS +G
Sbjct: 263 IVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGF 321
Query: 244 YKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGN--YAAVES 301
+ D FQET+ AM ++G EEQ +L++V+ +L LGNI FK+ N A++
Sbjct: 322 VPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPD 381
Query: 302 EEFLAFPAYLLGIN-QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH 360
+L+GIN D + LT R + + + EQA + +ALAKA +
Sbjct: 382 NTAAQKVCHLMGINVTDFTRSILTPRIKVGR-----DVVQKAQTKEQADFAVEALAKATY 436
Query: 361 ARVFDFLVDSINKAMEKDHEE--YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIE 418
R+F +++ +NKA++K H + +G+LDI GFEIF+ N FEQ CIN+ NEKLQQ+F
Sbjct: 437 ERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNH 496
Query: 419 LTLKAEQEEYVQEGIRWTPIEYFNNKIVC-DLIENKVNPPGIMSILDDVCATMHAVGEGA 477
EQEEY +EGI W I++ + C +LIE NPPG++++LD+ C A
Sbjct: 497 TMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKA----T 552
Query: 478 DQTLLQKLQMQIGSHEHFNSWNQ-----GFIIHHYAGKVSYDMDGFCERNRDVLFMDLIE 532
D++ ++KL + GSH F Q F I HYAGKV Y+ + +N D L ++
Sbjct: 553 DKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTS 612
Query: 533 LMQSSELPFIKSLFPE-------------------NLQADKKGRPTTAGSKIKKQANDLV 573
L+ +S F+ L+ + + KKG T G K+Q L+
Sbjct: 613 LLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLM 672
Query: 574 STLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFL 633
+TL TP+++RCI PN K+ + V Q+ G+ E IR+ R G+ R +FQ+F
Sbjct: 673 TTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFR 732
Query: 634 QRYAILTKATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRER 693
QRY IL P + KQ + +++++ +D + +++G+SK+F + L LEE R+
Sbjct: 733 QRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDL 791
Query: 694 KYDGYARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPE 753
K Q R ++ARK + + +++ + + + ++ RN+ + + P
Sbjct: 792 KITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPL 851
Query: 754 LQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLK 813
LQ + E D + K R + + + L + ++ + +K L++E L+
Sbjct: 852 LQVTRQEEEMQAKEDELQKTKERQQKAENE-------LKELEQKHSQLTEEKNLLQEQLQ 904
Query: 814 RKIEI---ERILSVSLSTMQDDI-FILHEQE 840
+ E+ + V L+ + ++ ILHE E
Sbjct: 905 AETELYAEAEEMRVRLAAKKQELEEILHEME 935
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 450 bits (1158), Expect = e-126
Identities = 292/871 (33%), Positives = 465/871 (53%), Gaps = 65/871 (7%)
Query: 17 KHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMY 76
K S V+DM L+ + E S++ NL++RY I+TY G + VNP+K +P + EK ++MY
Sbjct: 83 KFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY 142
Query: 77 QGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVS--- 133
+G ++E PPHIYA+AD YR+M+ DRE+Q ++ +GESGAGKT K ++ Y++ V+
Sbjct: 143 KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSH 202
Query: 134 ----------GGGTKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGE 183
G ++ +LQ+NP+LEAFGNAKTV+N+NSSRFGK+ I F G
Sbjct: 203 KGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGY 262
Query: 184 PDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGS 243
G I +LLEKSR + + ER+FHIFY +I GA + + L + + Y +LS +G
Sbjct: 263 IVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGF 321
Query: 244 YKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGN--YAAVES 301
+ D FQET+ AM ++G EEQ +L++V+ +L LGNI FK+ N A++
Sbjct: 322 VPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPD 381
Query: 302 EEFLAFPAYLLGIN-QDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH 360
+L+GIN D + LT R + + + EQA + +ALAKA +
Sbjct: 382 NTAAQKVCHLMGINVTDFTRSILTPRIKVGR-----DVVQKAQTKEQADFAVEALAKATY 436
Query: 361 ARVFDFLVDSINKAMEKDHEE--YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIE 418
R+F +++ +NKA++K H + +G+LDI GFEIF+ N FEQ CIN+ NEKLQQ+F
Sbjct: 437 ERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNH 496
Query: 419 LTLKAEQEEYVQEGIRWTPIEYFNNKIVC-DLIENKVNPPGIMSILDDVCATMHAVGEGA 477
EQEEY +EGI W I++ + C +LIE NPPG++++LD+ C A
Sbjct: 497 TMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKA----T 552
Query: 478 DQTLLQKLQMQIGSHEHFNSWNQ-----GFIIHHYAGKVSYDMDGFCERNRDVLFMDLIE 532
D++ ++KL + GSH F Q F I HYAGKV Y+ + +N D L ++
Sbjct: 553 DKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTS 612
Query: 533 LMQSSELPFIKSLFPE-------------------NLQADKKGRPTTAGSKIKKQANDLV 573
L+ +S F+ L+ + + KKG T G K+Q L+
Sbjct: 613 LLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLM 672
Query: 574 STLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFL 633
+TL TP+++RCI PN K+ + V Q+ G+ E IR+ R G+ R +FQ+F
Sbjct: 673 TTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFR 732
Query: 634 QRYAILTKATWPSWQGEEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRER 693
QRY IL P + KQ + +++++ +D + +++G+SK+F + L LEE R+
Sbjct: 733 QRYEILAANAIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRT-GVLAHLEEERDL 791
Query: 694 KYDGYARVIQKSWRKFVARKKYVQMREEASDLLLNKKERRRNSINRNFIGDYIGMEEHPE 753
K Q R ++ARK + + +++ + + + ++ RN+ + + P
Sbjct: 792 KITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPL 851
Query: 754 LQQFVGKREKIDFADTVTKYDRRFKGVKRDLLLTPKCLYLIGREKVKQGPDKGLVKEVLK 813
LQ + E D + K R + + + L + ++ + +K L++E L+
Sbjct: 852 LQVTRQEEEMQAKEDELQKTKERQQKAENE-------LKELEQKHSQLTEEKNLLQEQLQ 904
Query: 814 RKIEI---ERILSVSLSTMQDDI-FILHEQE 840
+ E+ + V L+ + ++ ILHE E
Sbjct: 905 AETELYAEAEEMRVRLAAKKQELEEILHEME 935
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 439 bits (1129), Expect = e-123
Identities = 279/750 (37%), Positives = 411/750 (54%), Gaps = 46/750 (6%)
Query: 12 QSHNVKHSGVDDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEK 71
Q + K ++DM +L+ + E +++ NLK+RY I+TY G ++VNP+K +P + +
Sbjct: 78 QQNPPKFDKIEDMAMLTFLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAE 137
Query: 72 EIEMYQGAAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISR 131
+ Y+G + E PPHI++++DN Y+ M+ DRENQ ++I+GESGAGKTV K ++ Y +
Sbjct: 138 VVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAS 197
Query: 132 VSGGGTKVQH---------VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGG 182
++ G + + ++D I+Q+NP LEAFGNAKTVRN+NSSRFGK+ I F G
Sbjct: 198 IAAIGDRGKKDNANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATG 257
Query: 183 EPDGGKISNFLLEKSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSG 242
+ I +LLEKSRV+ + ER++HIFYQ++ E L +T+ Y Y G
Sbjct: 258 KLASADIETYLLEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQG 317
Query: 243 SYKVDDIDDRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEVGNYAAVESE 302
V IDD E T A +V+G +EE+ V ++ I+H GN+ FK+ E +
Sbjct: 318 EVSVASIDDSEELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPD 377
Query: 303 --EFLAFPAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALH 360
E AYL+G+N L + L ++ K G +E + +V+Q Y+ ALAKA++
Sbjct: 378 GTEDADKSAYLMGLNSADLLKGLCHPRV--KVG--NEYVTKGQSVQQVYYSIGALAKAVY 433
Query: 361 ARVFDFLVDSINKAME-KDHEEYNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIEL 419
++F+++V IN +E K +Y IGVLDI GFEIF N FEQ CINF NEKLQQ F
Sbjct: 434 EKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHH 493
Query: 420 TLKAEQEEYVQEGIRWTPIEYFNNKIVC-DLIENKVNPPGIMSILDDVCATMHAVGEGAD 478
EQEEY +EGI WT I++ + C DLIE P GIMSIL++ C A D
Sbjct: 494 MFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIE---KPMGIMSILEEECMFPKA----TD 546
Query: 479 QTLLQKL-QMQIGSHEHF-------NSWNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDL 530
T KL +G +F F + HYAG V Y++ G+ E+N+D L +
Sbjct: 547 MTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETV 606
Query: 531 IELMQSSELPFIKSLFPENLQAD-----------KKGRP-TTAGSKIKKQANDLVSTLMK 578
+ L Q S L + +LF AD KKG T + ++ N L++ L
Sbjct: 607 VALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRT 666
Query: 579 CTPHYIRCIKPNETKKPRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAI 638
PH++RCI PNE K P + V HQ+ G+ E IR+ R G+ R ++ F QRY I
Sbjct: 667 THPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRI 726
Query: 639 LTKATWPSWQG-EEKQGVLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDG 697
L P Q + ++G LL S+++D +Q++ G +KVF KA L LLEEMR+ +
Sbjct: 727 LNPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKA-GLLGLLEEMRDERLSR 785
Query: 698 YARVIQKSWRKFVARKKYVQMREEASDLLL 727
+Q R + R ++ ++ E LL+
Sbjct: 786 IITRMQAQARGQLMRIEFKKIVERRDALLV 815
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,295,525
Number of Sequences: 37866
Number of extensions: 2098612
Number of successful extensions: 10414
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 248
Number of HSP's successfully gapped in prelim test: 252
Number of HSP's that attempted gapping in prelim test: 8832
Number of HSP's gapped (non-prelim): 1277
length of query: 1108
length of database: 18,247,518
effective HSP length: 113
effective length of query: 995
effective length of database: 13,968,660
effective search space: 13898816700
effective search space used: 13898816700
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.