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Search of human proteins with 55770886
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
(520 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 1089 0.0
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 205 9e-53
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 205 9e-53
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 204 1e-52
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 199 7e-51
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 196 6e-50
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 195 7e-50
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 195 7e-50
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 195 7e-50
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 193 4e-49
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 179 5e-45
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 174 1e-43
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 174 1e-43
gi|21361749 ubiquitin thioesterase 49 [Homo sapiens] 171 1e-42
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 149 6e-36
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 149 6e-36
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 144 3e-34
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 141 2e-33
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 141 2e-33
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 140 2e-33
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 140 2e-33
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 138 1e-32
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 138 1e-32
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 137 3e-32
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 137 3e-32
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 132 1e-30
gi|183397136 ubiquitin specific protease 20 [Homo sapiens] 132 1e-30
gi|183397134 ubiquitin specific protease 20 [Homo sapiens] 132 1e-30
gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ... 130 3e-30
gi|45267835 ubiquitin specific protease 50 [Homo sapiens] 129 5e-30
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 1089 bits (2816), Expect = 0.0
Identities = 520/520 (100%), Positives = 520/520 (100%)
Query: 1 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH 60
MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH
Sbjct: 1 MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKH 60
Query: 61 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN 120
YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN
Sbjct: 61 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQN 120
Query: 121 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI 180
LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI
Sbjct: 121 LENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNI 180
Query: 181 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE 240
EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE
Sbjct: 181 EQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPE 240
Query: 241 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK 300
SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK
Sbjct: 241 SLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNK 300
Query: 301 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP 360
CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP
Sbjct: 301 CCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP 360
Query: 361 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL 420
VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL
Sbjct: 361 VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYL 420
Query: 421 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG 480
RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG
Sbjct: 421 RNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG 480
Query: 481 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 520
RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL
Sbjct: 481 RWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 520
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 205 bits (521), Expect = 9e-53
Identities = 154/482 (31%), Positives = 226/482 (46%), Gaps = 82/482 (17%)
Query: 109 GLVQKVREHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTT------AICATGLR 162
GL Q + +++ A T K K+L S N KV+ S+ TGLR
Sbjct: 218 GLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSE-NEISQKVSDSSVKRRPIVTPGVTGLR 276
Query: 163 NLGNTCFMNAILQSLSNIEQFCCYFKEL--------------------PAVE-------- 194
NLGNTC+MN++LQ LS++ F F +L P +
Sbjct: 277 NLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNE 336
Query: 195 -------------------LRNGKTAGRRT--YHTRSQGDNNVSLVEEFRKTLCALWQGS 233
L G + GR+ + +SL E +W G
Sbjct: 337 CQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGK 396
Query: 234 QTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENS 293
SP ++ + VW+++P FRGY QQDA EF+ LLD + EL+ G S A+
Sbjct: 397 WALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELE--TTGTSLPAL----- 449
Query: 294 TLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRS 353
+ S + I VV IF G L ++V CL C +S +PF DLSL+ P +++
Sbjct: 450 -IPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCS-G 507
Query: 354 KNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQK-----------STKKFWIQK 402
K+ + P C + + L FT+ E L E ++Y+C +C K++ + K+ I
Sbjct: 508 KDIASQP-CLVTEMLAKFTETEAL-EGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICH 565
Query: 403 LPKVLCLHLKRFHWTA-YLRNKVDTYVEF-PLRGLDMKCYLLEPENSGPESCLYDLAAVV 460
LP+VL LHLKRF W+ R K+ +V F + ++ C ++ PE +YDL+AVV
Sbjct: 566 LPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVV 625
Query: 461 VHHGSGVGSGHYTAYA--THEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSD 518
+HHG G GSGHYTAY + G W H NDS +++ + V KA+AYILFY + + G
Sbjct: 626 MHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHS 685
Query: 519 KL 520
KL
Sbjct: 686 KL 687
Score = 75.9 bits (185), Expect = 8e-14
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Query: 23 SPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQH 82
+P W C C + +S W CL+CS V CGRY+ HA KH++++ H
Sbjct: 23 NPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKHFQES----------------SH 66
Query: 83 TVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLENST 141
V ++ + +CY CDD+V+ND G ++ +R L +++ + R L T
Sbjct: 67 PVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFLRSMGT 125
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 205 bits (521), Expect = 9e-53
Identities = 154/482 (31%), Positives = 226/482 (46%), Gaps = 82/482 (17%)
Query: 109 GLVQKVREHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTT------AICATGLR 162
GL Q + +++ A T K K+L S N KV+ S+ TGLR
Sbjct: 218 GLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSE-NEISQKVSDSSVKRRPIVTPGVTGLR 276
Query: 163 NLGNTCFMNAILQSLSNIEQFCCYFKEL--------------------PAVE-------- 194
NLGNTC+MN++LQ LS++ F F +L P +
Sbjct: 277 NLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNE 336
Query: 195 -------------------LRNGKTAGRRT--YHTRSQGDNNVSLVEEFRKTLCALWQGS 233
L G + GR+ + +SL E +W G
Sbjct: 337 CQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGK 396
Query: 234 QTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENS 293
SP ++ + VW+++P FRGY QQDA EF+ LLD + EL+ G S A+
Sbjct: 397 WALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELE--TTGTSLPAL----- 449
Query: 294 TLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRS 353
+ S + I VV IF G L ++V CL C +S +PF DLSL+ P +++
Sbjct: 450 -IPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCS-G 507
Query: 354 KNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQK-----------STKKFWIQK 402
K+ + P C + + L FT+ E L E ++Y+C +C K++ + K+ I
Sbjct: 508 KDIASQP-CLVTEMLAKFTETEAL-EGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICH 565
Query: 403 LPKVLCLHLKRFHWTA-YLRNKVDTYVEF-PLRGLDMKCYLLEPENSGPESCLYDLAAVV 460
LP+VL LHLKRF W+ R K+ +V F + ++ C ++ PE +YDL+AVV
Sbjct: 566 LPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVV 625
Query: 461 VHHGSGVGSGHYTAYA--THEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSD 518
+HHG G GSGHYTAY + G W H NDS +++ + V KA+AYILFY + + G
Sbjct: 626 MHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHS 685
Query: 519 KL 520
KL
Sbjct: 686 KL 687
Score = 75.9 bits (185), Expect = 8e-14
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Query: 23 SPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQH 82
+P W C C + +S W CL+CS V CGRY+ HA KH++++ H
Sbjct: 23 NPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKHFQES----------------SH 66
Query: 83 TVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLENST 141
V ++ + +CY CDD+V+ND G ++ +R L +++ + R L T
Sbjct: 67 PVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFLRSMGT 125
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 204 bits (520), Expect = 1e-52
Identities = 157/521 (30%), Positives = 234/521 (44%), Gaps = 88/521 (16%)
Query: 26 SWCCSVCRSNKSPW-VCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQHTV 84
S C VC ++ + CL+C V G + H KH E Q H +
Sbjct: 233 SCICHVCSTHMNRLHSCLSC--VFFGCFTEKHIHKHAETKQ----------------HHL 274
Query: 85 CMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHK---------KRK 135
+D YC+ C D+V + + ++ +E + L S T H+ K+
Sbjct: 275 AVDLYHGVIYCFMCKDYVYDKDIEQIAKETKEKILRLLTSTSTDVSHQQFMTSGFEDKQS 334
Query: 136 LLENSTLNSKLLKVNG-----STTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKEL 190
E KL+K S + GL NLGNTCFMN I+Q+L++I +F
Sbjct: 335 TCETKEQEPKLVKPKKKRRKKSVYTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFLS- 393
Query: 191 PAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIM 250
H ++ LV E A++ GS+T P L +++W
Sbjct: 394 --------------DKHKCIMTSPSLCLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHA 439
Query: 251 PNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVV 310
+ GY+QQDAHEF+ +LD LH + G QE A+N C N ++
Sbjct: 440 EHLAGYRQQDAHEFLIAILDVLHRHSKDDSGG-------QE-----ANNPNCCN---CII 484
Query: 311 TAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP---------- 360
IF G LQ++V C C + S DP D+SLD+P + S+N E
Sbjct: 485 DQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRDDHIP 544
Query: 361 -VCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAY 419
+ SL DCL+ FT E L + C+ C+ Q+STK+ ++KLP V C HLKRF
Sbjct: 545 GIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFEHVGK 604
Query: 420 LRNKVDTYVEFPLRGLDMKCYLLE------PENSGPESCL-----YDLAAVVVHHGSGVG 468
R K++T++ FPL LDM +L E P C+ Y L AV+ HHG+ +
Sbjct: 605 QRRKINTFISFPLE-LDMTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVINHHGT-LE 662
Query: 469 SGHYTAYATHE-GRWFHFNDSTVTLTDEETVVKAKAYILFY 508
SGHYT++ + +WF +D+ +T E ++ ++ Y+LFY
Sbjct: 663 SGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYSEGYLLFY 703
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 199 bits (505), Expect = 7e-51
Identities = 143/382 (37%), Positives = 196/382 (51%), Gaps = 38/382 (9%)
Query: 136 LLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCY-FKELPAVE 194
LL ++ + L K S +A GLRNLGNTCFMN+ILQ LSN + Y + L +
Sbjct: 35 LLLSTFVGLLLNKAKNSKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRD 94
Query: 195 LRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT-AFSPESLFYVVWKIMPNF 253
L +G A HT +LVEEF K + +W S SP + + P F
Sbjct: 95 LHHGSNA-----HT--------ALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRF 141
Query: 254 RGYQQQDAHEFMRYLLDHLHLE-----LQGGFNGVSRSAILQENSTLSASNKCCINGAST 308
GY QQDA EF+R+LLD LH E L+ N + + + K + +
Sbjct: 142 VGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKY-LEREDS 200
Query: 309 VVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCL 368
+ +F G L++ + C CG S FDPF DLSL I +KR P +L DC+
Sbjct: 201 RIGDLFVGQLKSSLTCTDCGYCSTVFDPFWDLSLPI-----AKRGY-----PEVTLMDCM 250
Query: 369 RSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYV 428
R FT + LD E C +C+ +++ KKF IQ+ PK+L LHLKRF + +K+ T+V
Sbjct: 251 RLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFV 310
Query: 429 EFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAY--ATHEGRWFHFN 486
FPLR LD++ + E N +Y+L AV H G+ +G GHYTAY + G W FN
Sbjct: 311 NFPLRDLDLREFASENTN----HAVYNLYAVSNHSGTTMG-GHYTAYCRSPGTGEWHTFN 365
Query: 487 DSTVTLTDEETVVKAKAYILFY 508
DS+VT V + AY+LFY
Sbjct: 366 DSSVTPMSSSQVRTSDAYLLFY 387
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 196 bits (497), Expect = 6e-50
Identities = 139/366 (37%), Positives = 189/366 (51%), Gaps = 38/366 (10%)
Query: 152 STTAICATGLRNLGNTCFMNAILQSLSNIEQFCCY-FKELPAVELRNGKTAGRRTYHTRS 210
S +A GLRNLGNTCFMN+ILQ LSN + Y + L +L +G A HT
Sbjct: 260 SKSAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGSNA-----HT-- 312
Query: 211 QGDNNVSLVEEFRKTLCALWQGSQT-AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLL 269
+LVEEF K + +W S SP + + P F GY QQDA EF+R+LL
Sbjct: 313 ------ALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLL 366
Query: 270 DHLHLE-----LQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNC 324
D LH E L+ N + + + K + + + +F G L++ + C
Sbjct: 367 DGLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKY-LEREDSRIGDLFVGQLKSSLTC 425
Query: 325 LICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYM 384
CG S FDPF DLSL I +KR P +L DC+R FT + LD E
Sbjct: 426 TDCGYCSTVFDPFWDLSLPI-----AKRGY-----PEVTLMDCMRLFTKEDVLDGDEKPT 475
Query: 385 CHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEP 444
C +C+ +++ KKF IQ+ PK+L LHLKRF + +K+ T+V FPLR LD++ + E
Sbjct: 476 CCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASEN 535
Query: 445 ENSGPESCLYDLAAVVVHHGSGVGSGHYTAY--ATHEGRWFHFNDSTVTLTDEETVVKAK 502
N +Y+L AV H G+ +G GHYTAY + G W FNDS+VT V +
Sbjct: 536 TN----HAVYNLYAVSNHSGTTMG-GHYTAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSD 590
Query: 503 AYILFY 508
AY+LFY
Sbjct: 591 AYLLFY 596
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 195 bits (496), Expect = 7e-50
Identities = 126/363 (34%), Positives = 181/363 (49%), Gaps = 46/363 (12%)
Query: 159 TGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVS- 217
TGLRNLGNTC+MN+ILQ L N YF R Y N +
Sbjct: 777 TGLRNLGNTCYMNSILQCLCNAPHLADYFN--------------RNCYQDDINRSNLLGH 822
Query: 218 ---LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHL 274
+ EEF + ALW G SP+ + KI F GY QQD+ E + +L+D LH
Sbjct: 823 KGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHE 882
Query: 275 ELQGGFNGVSRSAILQENSTLSASNKCCING-------ASTVVTAIFGGILQNEVNCLIC 327
+L N R +EN+ K + +++ A+F G ++ V CL C
Sbjct: 883 DLNKADN---RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTC 939
Query: 328 GTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHK 387
+SR F+ F+ LSL + S + C+L+DCLR F+ E+L + + C
Sbjct: 940 HKKSRTFEAFMYLSLPLASTSK------------CTLQDCLRLFSKEEKLTDNNRFYCSH 987
Query: 388 CKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENS 447
C+ ++ S KK I KLP VL +HLKRF + + K+ T V+FPL LD+ Y++ P+N+
Sbjct: 988 CRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNN 1047
Query: 448 GPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG--RWFHFNDSTVTLTDEETVVKAKAYI 505
+ Y+L +V H+G G+ GHYTAY + RWF F+D V+ +V + AYI
Sbjct: 1048 LKK---YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYI 1103
Query: 506 LFY 508
LFY
Sbjct: 1104 LFY 1106
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 195 bits (496), Expect = 7e-50
Identities = 126/363 (34%), Positives = 181/363 (49%), Gaps = 46/363 (12%)
Query: 159 TGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVS- 217
TGLRNLGNTC+MN+ILQ L N YF R Y N +
Sbjct: 777 TGLRNLGNTCYMNSILQCLCNAPHLADYFN--------------RNCYQDDINRSNLLGH 822
Query: 218 ---LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHL 274
+ EEF + ALW G SP+ + KI F GY QQD+ E + +L+D LH
Sbjct: 823 KGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHE 882
Query: 275 ELQGGFNGVSRSAILQENSTLSASNKCCING-------ASTVVTAIFGGILQNEVNCLIC 327
+L N R +EN+ K + +++ A+F G ++ V CL C
Sbjct: 883 DLNKADN---RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTC 939
Query: 328 GTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHK 387
+SR F+ F+ LSL + S + C+L+DCLR F+ E+L + + C
Sbjct: 940 HKKSRTFEAFMYLSLPLASTSK------------CTLQDCLRLFSKEEKLTDNNRFYCSH 987
Query: 388 CKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENS 447
C+ ++ S KK I KLP VL +HLKRF + + K+ T V+FPL LD+ Y++ P+N+
Sbjct: 988 CRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNN 1047
Query: 448 GPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG--RWFHFNDSTVTLTDEETVVKAKAYI 505
+ Y+L +V H+G G+ GHYTAY + RWF F+D V+ +V + AYI
Sbjct: 1048 LKK---YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYI 1103
Query: 506 LFY 508
LFY
Sbjct: 1104 LFY 1106
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 195 bits (496), Expect = 7e-50
Identities = 126/363 (34%), Positives = 181/363 (49%), Gaps = 46/363 (12%)
Query: 159 TGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVS- 217
TGLRNLGNTC+MN+ILQ L N YF R Y N +
Sbjct: 777 TGLRNLGNTCYMNSILQCLCNAPHLADYFN--------------RNCYQDDINRSNLLGH 822
Query: 218 ---LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHL 274
+ EEF + ALW G SP+ + KI F GY QQD+ E + +L+D LH
Sbjct: 823 KGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHE 882
Query: 275 ELQGGFNGVSRSAILQENSTLSASNKCCING-------ASTVVTAIFGGILQNEVNCLIC 327
+L N R +EN+ K + +++ A+F G ++ V CL C
Sbjct: 883 DLNKADN---RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTC 939
Query: 328 GTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHK 387
+SR F+ F+ LSL + S + C+L+DCLR F+ E+L + + C
Sbjct: 940 HKKSRTFEAFMYLSLPLASTSK------------CTLQDCLRLFSKEEKLTDNNRFYCSH 987
Query: 388 CKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENS 447
C+ ++ S KK I KLP VL +HLKRF + + K+ T V+FPL LD+ Y++ P+N+
Sbjct: 988 CRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNN 1047
Query: 448 GPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG--RWFHFNDSTVTLTDEETVVKAKAYI 505
+ Y+L +V H+G G+ GHYTAY + RWF F+D V+ +V + AYI
Sbjct: 1048 LKK---YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYI 1103
Query: 506 LFY 508
LFY
Sbjct: 1104 LFY 1106
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 193 bits (490), Expect = 4e-49
Identities = 152/496 (30%), Positives = 221/496 (44%), Gaps = 82/496 (16%)
Query: 41 CLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDD 100
CL C C KKH + H K+++ H + +D YC+ C D
Sbjct: 76 CLYCVFFGC------FTKKHIHE-------HAKAKR-----HNLAIDLMYGGIYCFLCQD 117
Query: 101 FVVNDTKLGLVQKVREH----LQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAI 156
++ D + ++ K + +Q + T + K+ LE N K K+ + T I
Sbjct: 118 YIY-DKDMEIIAKEEQRKAWKMQGVGEKFSTWEPTKRE--LELLKHNPKRRKITSNCT-I 173
Query: 157 CATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNV 216
GL NLGNTCFMN I+Q+L++ +F H +
Sbjct: 174 GLRGLINLGNTCFMNCIVQALTHTPLLRDFFLS---------------DRHRCEMQSPSS 218
Query: 217 SLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLEL 276
LV E + G ++ P L ++VW + GY+QQDAHEF+ LD LH
Sbjct: 219 CLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHC 278
Query: 277 QGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDP 336
+G NG A+N N + ++ IF G LQ++V C +C S DP
Sbjct: 279 KGDDNGKK------------ANNP---NHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDP 323
Query: 337 FLDLSLDIPSQ------FRSKRSKNQENGP-----VCSLRDCLRSFTDLEELDETELYMC 385
F D+SLD+P N NG +L DCLR FT E L + C
Sbjct: 324 FWDISLDLPGSSTPFWPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKC 383
Query: 386 HKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLL--- 442
C Q+STK+ ++KLP V C HLKRF +A LR K+ TYV FPL LDM ++
Sbjct: 384 SGCHSYQESTKQLTMKKLPIVACFHLKRFEHSAKLRRKITTYVSFPLE-LDMTPFMASSK 442
Query: 443 ---------EPENSGPESCLYDLAAVVVHHGSGVGSGHYTAY-ATHEGRWFHFNDSTVTL 492
+P +S Y L AVV H G+ + SGHYT++ H+ +WF +D+ +T
Sbjct: 443 ESRMNGQYQQPTDSLNNDNKYSLFAVVNHQGT-LESGHYTSFIRQHKDQWFKCDDAIITK 501
Query: 493 TDEETVVKAKAYILFY 508
+ V+ ++ Y+LFY
Sbjct: 502 ASIKDVLDSEGYLLFY 517
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 179 bits (454), Expect = 5e-45
Identities = 131/398 (32%), Positives = 189/398 (47%), Gaps = 67/398 (16%)
Query: 152 STTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFK------ELPAVELRNGKTAGRRT 205
S+ I GL NLGNTCFMN I+Q+L++ +F E+P+ EL
Sbjct: 71 SSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPEL---------- 120
Query: 206 YHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFM 265
LV E L+ G+ + P L ++VW + GY+QQDAHEF+
Sbjct: 121 -----------CLVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFL 169
Query: 266 RYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCL 325
LD LH +G G + A+N N + ++ IF G LQ++V C
Sbjct: 170 IAALDVLHRHCKGDDVGKA------------ANNP---NHCNCIIDQIFTGGLQSDVTCQ 214
Query: 326 ICGTESRKFDPFLDLSLDIPSQFRS--------KRSKNQENG--PVCSLRDCLRSFTDLE 375
C S DP D+SLD+P S + S N E+ + +L DCLR FT E
Sbjct: 215 ACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPE 274
Query: 376 ELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGL 435
L + C C+ Q+STK+ + KLP V C H KRF +A R K+ TY+ FPL L
Sbjct: 275 HLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLE-L 333
Query: 436 DMKCYLLE------------PENSGPESCLYDLAAVVVHHGSGVGSGHYTAYAT-HEGRW 482
DM ++ P NSG Y L AVV H G+ + SGHYT++ H+ +W
Sbjct: 334 DMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGT-LESGHYTSFIRHHKDQW 392
Query: 483 FHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSDKL 520
F +D+ +T + V+ ++ Y+LFY + + S+K+
Sbjct: 393 FKCDDAVITKASIKDVLDSEGYLLFYHKQVLEHESEKV 430
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 174 bits (442), Expect = 1e-43
Identities = 127/373 (34%), Positives = 175/373 (46%), Gaps = 54/373 (14%)
Query: 160 GLRNLGNTCFMNAILQSLSN---IEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNV 216
GLRNLGNTCF+NA+LQ LS+ + FC RR + G
Sbjct: 213 GLRNLGNTCFLNAVLQCLSSTRPLRDFCL-----------------RRDFRQEVPGGGRA 255
Query: 217 S-LVEEFRKTLCALWQ-GSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHL 274
L E F + ALW S A +P V K +P+F GY QQDA EF++ L++ LHL
Sbjct: 256 QELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHL 315
Query: 275 ELQGG--------FNGV-----SRSAILQENSTLSASNKC------CINGASTVVTAIFG 315
E+ NG R L E LS ++ + + + +F
Sbjct: 316 EINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFV 375
Query: 316 GILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLE 375
G L++ + C CG S F+ F DLSL IP K G V SLRDC FT E
Sbjct: 376 GQLKSCLKCQACGYRSTTFEVFCDLSLPIPK-------KGFAGGKV-SLRDCFNLFTKEE 427
Query: 376 ELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGL 435
EL+ +C +C++K +STKK +Q+ P++L LHL RF + K V+FPL+ L
Sbjct: 428 ELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRL 487
Query: 436 DMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDE 495
+ + + S +Y L A+ H GS V GHYTA + W +NDS V+ E
Sbjct: 488 SLGDFASDKAGSP----VYQLYALCNHSGS-VHYGHYTALCRCQTGWHVYNDSRVSPVSE 542
Query: 496 ETVVKAKAYILFY 508
V ++ Y+LFY
Sbjct: 543 NQVASSEGYVLFY 555
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 174 bits (442), Expect = 1e-43
Identities = 127/373 (34%), Positives = 175/373 (46%), Gaps = 54/373 (14%)
Query: 160 GLRNLGNTCFMNAILQSLSN---IEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNV 216
GLRNLGNTCF+NA+LQ LS+ + FC RR + G
Sbjct: 213 GLRNLGNTCFLNAVLQCLSSTRPLRDFCL-----------------RRDFRQEVPGGGRA 255
Query: 217 S-LVEEFRKTLCALWQ-GSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHL 274
L E F + ALW S A +P V K +P+F GY QQDA EF++ L++ LHL
Sbjct: 256 QELTEAFADVIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHL 315
Query: 275 ELQGG--------FNGV-----SRSAILQENSTLSASNKC------CINGASTVVTAIFG 315
E+ NG R L E LS ++ + + + +F
Sbjct: 316 EINRRGRRAPPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFV 375
Query: 316 GILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLE 375
G L++ + C CG S F+ F DLSL IP K G V SLRDC FT E
Sbjct: 376 GQLKSCLKCQACGYRSTTFEVFCDLSLPIPK-------KGFAGGKV-SLRDCFNLFTKEE 427
Query: 376 ELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGL 435
EL+ +C +C++K +STKK +Q+ P++L LHL RF + K V+FPL+ L
Sbjct: 428 ELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRL 487
Query: 436 DMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDE 495
+ + + S +Y L A+ H GS V GHYTA + W +NDS V+ E
Sbjct: 488 SLGDFASDKAGSP----VYQLYALCNHSGS-VHYGHYTALCRCQTGWHVYNDSRVSPVSE 542
Query: 496 ETVVKAKAYILFY 508
V ++ Y+LFY
Sbjct: 543 NQVASSEGYVLFY 555
>gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]
Length = 640
Score = 171 bits (434), Expect = 1e-42
Identities = 123/377 (32%), Positives = 180/377 (47%), Gaps = 70/377 (18%)
Query: 159 TGLRNLGNTCFMNAILQSLSNIEQFC-CYFKELPAV------ELRNGKT--AGRRTYHTR 209
TGLRNLGNTC+MN+ILQ LS++++F C+ P+ + NGKT +G+ T +
Sbjct: 253 TGLRNLGNTCYMNSILQVLSHLQKFRECFLNLDPSKTEHLFPKATNGKTQLSGKPTNSSA 312
Query: 210 SQ------------------------------------GDNNVSLVEEFRKTLCALWQGS 233
++ ++SL E +W G
Sbjct: 313 TELSLRNDRAEACEREGFCWNGRASISRSLELIQNKEPSSKHISLCRELHTLFRVMWSGK 372
Query: 234 QTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENS 293
SP ++ + VW ++P FRGY QQDA EF+ LL + EL+ G +R +
Sbjct: 373 WALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQELES--EGTTRRIL----- 425
Query: 294 TLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRS-KR 352
+ S + VV IF G L ++V C+ C +S +PF DLSL+ P ++ ++
Sbjct: 426 -IPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYHCIEK 484
Query: 353 SKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKST-----------KKFWIQ 401
N C L + L FT+ E L E +Y C +C K++ + K+ I
Sbjct: 485 GFVPLNQTECLLTEMLAKFTETEAL-EGRIYACDQCNSKRRKSNPKPLVLSEARKQLMIY 543
Query: 402 KLPKVLCLHLKRFHWTA-YLRNKVDTYVEFPLRGLDMKCYLLEPENSG--PESCLYDLAA 458
+LP+VL LHLKRF W+ R K+ +V F + L M+ Y S E+ YDL+A
Sbjct: 544 RLPQVLRLHLKRFRWSGRNHREKIGVHVVFD-QVLTMEPYCCRDMLSSLDKETFAYDLSA 602
Query: 459 VVVHHGSGVGSGHYTAY 475
VV+HHG G GSGHYTAY
Sbjct: 603 VVMHHGKGFGSGHYTAY 619
Score = 75.1 bits (183), Expect = 1e-13
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 16/96 (16%)
Query: 23 SPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQH 82
+P WCC C + +S W CL CS V CGRY+ HA KH+E+ H
Sbjct: 20 NPQKWCCLECATTESVWACLKCSHVACGRYIEDHALKHFEE----------------TGH 63
Query: 83 TVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHL 118
+ M+ +CY C D+V+ND G ++ +R L
Sbjct: 64 PLAMEVRDLYVFCYLCKDYVLNDNPEGDLKLLRSSL 99
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 149 bits (376), Expect = 6e-36
Identities = 109/360 (30%), Positives = 163/360 (45%), Gaps = 71/360 (19%)
Query: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLV 219
GL NLGNTCF+NA +Q L+ Y H RS + ++
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLSKE---------------HARSCHQGSFCML 167
Query: 220 EEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGG 279
+ + + S A P S + KI +FR Q+DAHEF+RY +D
Sbjct: 168 CVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTID--------- 218
Query: 280 FNGVSRSAILQENSTLSASNKCCING---------ASTVVTAIFGGILQNEVNCLICGTE 330
A K C+NG A+T+V IFGG L++ V C +C +
Sbjct: 219 -----------------AMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSV 261
Query: 331 SRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKK 390
S +DP+LD++L+I R+ L F + L YMC KCKK
Sbjct: 262 SDTYDPYLDVALEIRQAANIVRA--------------LELFVKADVLSGENAYMCAKCKK 307
Query: 391 KQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPE 450
K ++K+F I + VL L LKRF + K+ V +P L+++ Y+ +N+G +
Sbjct: 308 KVPASKRFTIHRTSNVLTLSLKRF--ANFSGGKITKDVGYP-EFLNIRPYM--SQNNG-D 361
Query: 451 SCLYDLAAVVVHHGSGVGSGHYTAYA-THEGRWFHFNDSTVTLTDEETVVKAKAYILFYV 509
+Y L AV+VH G +GHY Y G+W+ NDS V ++ + V+ +AY+LFY+
Sbjct: 362 PVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKVVLNQQAYVLFYL 421
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 149 bits (376), Expect = 6e-36
Identities = 108/361 (29%), Positives = 162/361 (44%), Gaps = 54/361 (14%)
Query: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLV 219
GL+NLGNTCF NA LQ L+ Y H+++ ++
Sbjct: 112 GLQNLGNTCFANAALQCLTYTPPLANYMLSHE---------------HSKTCHAEGFCMM 156
Query: 220 EEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGG 279
+ + P + + +I +FR Q+DAHEF++Y +D + G
Sbjct: 157 CTMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNG 216
Query: 280 FNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLD 339
N + R A+T+V IFGG L++ V CL C S FDP+LD
Sbjct: 217 SNKLDRHT-----------------QATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLD 259
Query: 340 LSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFW 399
++L+I + S+ L F E+LD Y C KCKK ++K+F
Sbjct: 260 ITLEIKA--------------AQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFT 305
Query: 400 IQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAV 459
I + VL L LKRF + K+ V++P LD++ Y+ +P E +Y L AV
Sbjct: 306 IHRSSNVLTLSLKRF--ANFTGGKIAKDVKYP-EYLDIRPYMSQPNG---EPIVYVLYAV 359
Query: 460 VVHHGSGVGSGHYTAY-ATHEGRWFHFNDSTVTLTDEETVVKAKAYILFYV-EHQAKAGS 517
+VH G +GHY Y G W+ NDS V+ +D +V+ +AY+LFY+ H K G
Sbjct: 360 LVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQAYVLFYIRSHDVKNGG 419
Query: 518 D 518
+
Sbjct: 420 E 420
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 144 bits (362), Expect = 3e-34
Identities = 115/369 (31%), Positives = 163/369 (44%), Gaps = 62/369 (16%)
Query: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLV 219
GL N GNTC+ N++LQ+L FC F+E + +SQ SL+
Sbjct: 40 GLVNFGNTCYCNSVLQAL----YFCRPFRE--------------KVLAYKSQPRKKESLL 81
Query: 220 EEFRKTLCALWQGSQT------AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLH 273
L L+ T P+ + K F Y QQDAHEF+ YLL+ +
Sbjct: 82 T----CLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIA 137
Query: 274 LELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRK 333
LQ ++ L + + +N + T V IF G L NE CL C T S K
Sbjct: 138 DILQEERKQEKQNGRLPNGNIDNENNNSTPD--PTWVDEIFQGTLTNETRCLTCETISSK 195
Query: 334 FDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQK 393
+ FLDLS+D+ S+ CLR F++ E L Y C +C+ KQ+
Sbjct: 196 DEDFLDLSVDVEQN--------------TSITHCLRGFSNTETLCSEYKYYCEECRSKQE 241
Query: 394 STKKFWIQKLPKVLCLHLKRFHWTAYLR--NKVDTYVEFPLRGLDMKCYLLEPENSGPES 451
+ K+ ++KLP +L LHLKRF + L K+ V FP L+++ + + + P+
Sbjct: 242 AHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFP---LELRLFNTSGDATNPDR 298
Query: 452 CLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVK----------- 500
+YDL AVVVH GSG GHY A W F+D V D + + +
Sbjct: 299 -MYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKN 357
Query: 501 -AKAYILFY 508
YILFY
Sbjct: 358 SESGYILFY 366
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 141 bits (355), Expect = 2e-33
Identities = 83/246 (33%), Positives = 123/246 (50%), Gaps = 37/246 (15%)
Query: 308 TVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQ-------------------- 347
+V++ IF G + + V CL C S + F DLSL IP +
Sbjct: 473 SVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGS 532
Query: 348 ------------FRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKST 395
F + K+ GPV +L+DCL +F +EL +Y C KCKK +
Sbjct: 533 CGEAYAPQGWIAFFMEYVKSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGV 592
Query: 396 KKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYD 455
K +Q P++LC+HLKRF K+ T+V FPL GLD++ +L ++S + YD
Sbjct: 593 KFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFL--AKDSPAQIVTYD 650
Query: 456 LAAVVVHHGSGVGSGHYTAYATH--EGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQA 513
L +V+ HHG+ SGHY AY + W+ F+D +VT E TV A+AY+LFY +
Sbjct: 651 LLSVICHHGT-ASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQNAEAYVLFYRKSSE 709
Query: 514 KAGSDK 519
+A ++
Sbjct: 710 EAQKER 715
Score = 101 bits (251), Expect = 2e-21
Identities = 84/292 (28%), Positives = 126/292 (43%), Gaps = 59/292 (20%)
Query: 3 CPHLSSSVCIAPDSAKFPNGSPSSWCCSVCR-SNKSPWVCLT--CSSVHCGRYVNGHAKK 59
CPHL S I + S C C+ + W CL CS V CG H+
Sbjct: 39 CPHLDSVGEITKEDLI----QKSLGTCQDCKVQGPNLWACLENRCSYVGCGESQVDHSTI 94
Query: 60 HYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGL---VQKVRE 116
H ++ + H + ++ ++ +CY C V D KLG + VR+
Sbjct: 95 HSQETK----------------HYLTVNLTTLRVWCYACSKEVFLDRKLGTQPSLPHVRQ 138
Query: 117 HLQNLENSAFTADRHKKRKLLENSTLNSKLLKV----------NGSTTAICATGLRNLGN 166
Q ENS + K+ N+TL + L+ V A TGL+N+GN
Sbjct: 139 PHQIQENSV------QDFKIPSNTTLKTPLVAVFDDLDIEADEEDELRARGLTGLKNIGN 192
Query: 167 TCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTL 226
TC+MNA LQ+LSN +F + + ++ D ++ + + K +
Sbjct: 193 TCYMNAALQALSNCPPLTQFFLDCGGL----------------ARTDKKPAICKSYLKLM 236
Query: 227 CALWQGSQT-AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
LW S+ + P +LF + + P FRGY QQDA EF+R L+D LH EL+
Sbjct: 237 TELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELK 288
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 141 bits (355), Expect = 2e-33
Identities = 69/160 (43%), Positives = 106/160 (66%), Gaps = 6/160 (3%)
Query: 360 PVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAY 419
P L+DC+ FT E+L + + C CK+ Q++TKK + LP VL +HLKRF ++ Y
Sbjct: 755 PFVKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRY 814
Query: 420 LRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATH- 478
+R+K+DT V+FP+ LDM +L+ P N+GP C Y+L AV H+G G+G GHYTA+A +
Sbjct: 815 MRDKLDTLVDFPINDLDMSEFLINP-NAGP--CRYNLIAVSNHYG-GMGGGHYTAFAKNK 870
Query: 479 -EGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGS 517
+G+W++F+DS+V+ E+ +V AY+LFY +G+
Sbjct: 871 DDGKWYYFDDSSVSTASEDQIVSKAAYVLFYQRQDTFSGT 910
Score = 84.3 bits (207), Expect = 2e-16
Identities = 63/208 (30%), Positives = 89/208 (42%), Gaps = 32/208 (15%)
Query: 150 NGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTR 209
N +C GL NLGNTCFMN+ +Q LSN YF N K Y
Sbjct: 253 NNEQPGLC--GLSNLGNTCFMNSAIQCLSNTPPLTEYFL--------NDK------YQEE 296
Query: 210 SQGDNNVSLVEEFRKTLCAL----WQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFM 265
DN + + E K+ L W G + +P + V + P F GYQQQD E +
Sbjct: 297 LNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELL 356
Query: 266 RYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGA--------STVVTAIFGGI 317
+LLD LH +L N + + +Q +K A +++ IF G+
Sbjct: 357 AFLLDGLHEDL----NRIRKKPYIQLKDADGRPDKVVAEEAWENHLKRNDSIIVDIFHGL 412
Query: 318 LQNEVNCLICGTESRKFDPFLDLSLDIP 345
++ + C C S FDPF L+L +P
Sbjct: 413 FKSTLVCPECAKISVTFDPFCYLTLPLP 440
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 140 bits (354), Expect = 2e-33
Identities = 70/148 (47%), Positives = 101/148 (68%), Gaps = 6/148 (4%)
Query: 363 SLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRN 422
+LRDC+ FT +E L E + + C CKK Q++TKKF + LPK+L +HLKRF + Y R+
Sbjct: 777 ALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRD 836
Query: 423 KVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHE--G 480
K+DT VEFP+RGL+M ++ N +YDL AV H+G+ +G GHYTAYA ++ G
Sbjct: 837 KLDTVVEFPIRGLNMSEFVC---NLSARPYVYDLIAVSNHYGA-MGVGHYTAYAKNKLNG 892
Query: 481 RWFHFNDSTVTLTDEETVVKAKAYILFY 508
+W++F+DS V+L E+ +V AY+LFY
Sbjct: 893 KWYYFDDSNVSLASEDQIVTKAAYVLFY 920
Score = 83.6 bits (205), Expect = 4e-16
Identities = 58/195 (29%), Positives = 84/195 (43%), Gaps = 24/195 (12%)
Query: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYF-KELPAVELRNGKTAGRRTYHTRSQGDNNVSL 218
GL NLGNTCFMN+ LQ LSN YF K+ E+ G + +
Sbjct: 303 GLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKG-----------EI 351
Query: 219 VEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQG 278
E + + + +W G +P V + P F GYQQQD+ E + +LLD LH +L
Sbjct: 352 AEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDL-- 409
Query: 279 GFNGVSRSAILQENSTLSASNKCCINGA--------STVVTAIFGGILQNEVNCLICGTE 330
N V + L+ + A +V+ F G+ ++ + C C
Sbjct: 410 --NRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKV 467
Query: 331 SRKFDPFLDLSLDIP 345
S FDPF L+L +P
Sbjct: 468 SVTFDPFCYLTLPLP 482
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 140 bits (354), Expect = 2e-33
Identities = 70/148 (47%), Positives = 101/148 (68%), Gaps = 6/148 (4%)
Query: 363 SLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRN 422
+LRDC+ FT +E L E + + C CKK Q++TKKF + LPK+L +HLKRF + Y R+
Sbjct: 730 ALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRD 789
Query: 423 KVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATHE--G 480
K+DT VEFP+RGL+M ++ N +YDL AV H+G+ +G GHYTAYA ++ G
Sbjct: 790 KLDTVVEFPIRGLNMSEFVC---NLSARPYVYDLIAVSNHYGA-MGVGHYTAYAKNKLNG 845
Query: 481 RWFHFNDSTVTLTDEETVVKAKAYILFY 508
+W++F+DS V+L E+ +V AY+LFY
Sbjct: 846 KWYYFDDSNVSLASEDQIVTKAAYVLFY 873
Score = 84.3 bits (207), Expect = 2e-16
Identities = 71/260 (27%), Positives = 107/260 (41%), Gaps = 47/260 (18%)
Query: 116 EHLQNLENSAFTADRHKKRKLL-----ENSTLNSKLLKVNGS----------------TT 154
E L L+N+ A ++ + L+ E+ T + L+ NGS
Sbjct: 193 EQLSKLDNTVQDAGLYQGQVLVIEPQNEDGTWPRQTLQSNGSGFSASYNCQEPPSSHIQP 252
Query: 155 AICATGLRNLGNTCFMNAILQSLSNIEQFCCYF-KELPAVELRNGKTAGRRTYHTRSQGD 213
+C GL NLGNTCFMN+ LQ LSN YF K+ E+ G +
Sbjct: 253 GLC--GLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKG-------- 302
Query: 214 NNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLH 273
+ E + + + +W G +P V + P F GYQQQD+ E + +LLD LH
Sbjct: 303 ---EIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLH 359
Query: 274 LELQGGFNGVSRSAILQENSTLSASNKCCINGA--------STVVTAIFGGILQNEVNCL 325
+L N V + L+ + A +V+ F G+ ++ + C
Sbjct: 360 EDL----NRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCP 415
Query: 326 ICGTESRKFDPFLDLSLDIP 345
C S FDPF L+L +P
Sbjct: 416 ECAKVSVTFDPFCYLTLPLP 435
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
sapiens]
Length = 359
Score = 138 bits (347), Expect = 1e-32
Identities = 114/366 (31%), Positives = 158/366 (43%), Gaps = 56/366 (15%)
Query: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNV--S 217
GL N GNTC+ N++LQ+L FC F+E Y + + N+
Sbjct: 29 GLVNFGNTCYCNSVLQAL----YFCRPFRE------------NVLAYKAQQKKKENLLTC 72
Query: 218 LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
L + F A + P+ + K F Y QQDAHEF+ YLL+ + LQ
Sbjct: 73 LADLFHSI--ATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQ 130
Query: 278 GGFNGVSRSAILQE-NSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDP 336
++ L+ N A N T V IF G L NE CL C T S K +
Sbjct: 131 EEKKQEKQNGKLKNGNMNEPAENN---KPELTWVHEIFQGTLTNETRCLNCETVSSKDED 187
Query: 337 FLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTK 396
FLDLS+D+ S+ CLR F++ E L + Y C C KQ++ K
Sbjct: 188 FLDLSVDVEQN--------------TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQK 233
Query: 397 KFWIQKLPKVLCLHLKRFHWTAYLR--NKVDTYVEFPLRGLDMKCYLLEPENSGPESCLY 454
+ ++KLP +L LHLKRF + L K+ V FP L+++ + + + +Y
Sbjct: 234 RMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFP---LELRLFNTSSDAVNLDR-MY 289
Query: 455 DLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVK------------AK 502
DL AVVVH GSG GHY G W F+D V D + + +
Sbjct: 290 DLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES 349
Query: 503 AYILFY 508
YILFY
Sbjct: 350 GYILFY 355
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
Length = 366
Score = 138 bits (347), Expect = 1e-32
Identities = 114/366 (31%), Positives = 158/366 (43%), Gaps = 56/366 (15%)
Query: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNV--S 217
GL N GNTC+ N++LQ+L FC F+E Y + + N+
Sbjct: 36 GLVNFGNTCYCNSVLQAL----YFCRPFRE------------NVLAYKAQQKKKENLLTC 79
Query: 218 LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
L + F A + P+ + K F Y QQDAHEF+ YLL+ + LQ
Sbjct: 80 LADLFHSI--ATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQ 137
Query: 278 GGFNGVSRSAILQE-NSTLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDP 336
++ L+ N A N T V IF G L NE CL C T S K +
Sbjct: 138 EEKKQEKQNGKLKNGNMNEPAENN---KPELTWVHEIFQGTLTNETRCLNCETVSSKDED 194
Query: 337 FLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTK 396
FLDLS+D+ S+ CLR F++ E L + Y C C KQ++ K
Sbjct: 195 FLDLSVDVEQN--------------TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQK 240
Query: 397 KFWIQKLPKVLCLHLKRFHWTAYLR--NKVDTYVEFPLRGLDMKCYLLEPENSGPESCLY 454
+ ++KLP +L LHLKRF + L K+ V FP L+++ + + + +Y
Sbjct: 241 RMRVKKLPMILALHLKRFKYMEQLHRYTKLSYRVVFP---LELRLFNTSSDAVNLDR-MY 296
Query: 455 DLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDSTVTLTDEETVVK------------AK 502
DL AVVVH GSG GHY G W F+D V D + + +
Sbjct: 297 DLVAVVVHCGSGPNRGHYITIVKSHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSES 356
Query: 503 AYILFY 508
YILFY
Sbjct: 357 GYILFY 362
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 137 bits (344), Expect = 3e-32
Identities = 81/254 (31%), Positives = 122/254 (48%), Gaps = 45/254 (17%)
Query: 308 TVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQEN--------- 358
+V++ IF G + + V CL C S + F DLSL IP + + + +
Sbjct: 473 SVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGS 532
Query: 359 -------------------------------GPVCSLRDCLRSFTDLEELDETELYMCHK 387
GPV +L+DCL +F +EL +Y C K
Sbjct: 533 CGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEK 592
Query: 388 CKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENS 447
CKK + K +Q P++LC+HLKRF K+ T+V FPL GLD++ +L ++S
Sbjct: 593 CKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFL--AKDS 650
Query: 448 GPESCLYDLAAVVVHHGSGVGSGHYTAYATH--EGRWFHFNDSTVTLTDEETVVKAKAYI 505
+ YDL +V+ HHG+ SGHY AY + W+ F+D +VT E TV A+AY+
Sbjct: 651 PAQIVTYDLLSVICHHGT-ASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQNAEAYV 709
Query: 506 LFYVEHQAKAGSDK 519
LFY + +A ++
Sbjct: 710 LFYRKSSEEAQKER 723
Score = 101 bits (251), Expect = 2e-21
Identities = 84/292 (28%), Positives = 126/292 (43%), Gaps = 59/292 (20%)
Query: 3 CPHLSSSVCIAPDSAKFPNGSPSSWCCSVCR-SNKSPWVCLT--CSSVHCGRYVNGHAKK 59
CPHL S I + S C C+ + W CL CS V CG H+
Sbjct: 39 CPHLDSVGEITKEDLI----QKSLGTCQDCKVQGPNLWACLENRCSYVGCGESQVDHSTI 94
Query: 60 HYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGL---VQKVRE 116
H ++ + H + ++ ++ +CY C V D KLG + VR+
Sbjct: 95 HSQETK----------------HYLTVNLTTLRVWCYACSKEVFLDRKLGTQPSLPHVRQ 138
Query: 117 HLQNLENSAFTADRHKKRKLLENSTLNSKLLKV----------NGSTTAICATGLRNLGN 166
Q ENS + K+ N+TL + L+ V A TGL+N+GN
Sbjct: 139 PHQIQENSV------QDFKIPSNTTLKTPLVAVFDDLDIEADEEDELRARGLTGLKNIGN 192
Query: 167 TCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTL 226
TC+MNA LQ+LSN +F + + ++ D ++ + + K +
Sbjct: 193 TCYMNAALQALSNCPPLTQFFLDCGGL----------------ARTDKKPAICKSYLKLM 236
Query: 227 CALWQGSQT-AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
LW S+ + P +LF + + P FRGY QQDA EF+R L+D LH EL+
Sbjct: 237 TELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELK 288
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 137 bits (344), Expect = 3e-32
Identities = 81/254 (31%), Positives = 122/254 (48%), Gaps = 45/254 (17%)
Query: 308 TVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQEN--------- 358
+V++ IF G + + V CL C S + F DLSL IP + + + +
Sbjct: 442 SVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVKAGS 501
Query: 359 -------------------------------GPVCSLRDCLRSFTDLEELDETELYMCHK 387
GPV +L+DCL +F +EL +Y C K
Sbjct: 502 CGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEK 561
Query: 388 CKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENS 447
CKK + K +Q P++LC+HLKRF K+ T+V FPL GLD++ +L ++S
Sbjct: 562 CKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFL--AKDS 619
Query: 448 GPESCLYDLAAVVVHHGSGVGSGHYTAYATH--EGRWFHFNDSTVTLTDEETVVKAKAYI 505
+ YDL +V+ HHG+ SGHY AY + W+ F+D +VT E TV A+AY+
Sbjct: 620 PAQIVTYDLLSVICHHGT-ASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTVQNAEAYV 678
Query: 506 LFYVEHQAKAGSDK 519
LFY + +A ++
Sbjct: 679 LFYRKSSEEAQKER 692
Score = 101 bits (251), Expect = 2e-21
Identities = 84/292 (28%), Positives = 126/292 (43%), Gaps = 59/292 (20%)
Query: 3 CPHLSSSVCIAPDSAKFPNGSPSSWCCSVCR-SNKSPWVCLT--CSSVHCGRYVNGHAKK 59
CPHL S I + S C C+ + W CL CS V CG H+
Sbjct: 8 CPHLDSVGEITKEDLI----QKSLGTCQDCKVQGPNLWACLENRCSYVGCGESQVDHSTI 63
Query: 60 HYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGL---VQKVRE 116
H ++ + H + ++ ++ +CY C V D KLG + VR+
Sbjct: 64 HSQETK----------------HYLTVNLTTLRVWCYACSKEVFLDRKLGTQPSLPHVRQ 107
Query: 117 HLQNLENSAFTADRHKKRKLLENSTLNSKLLKV----------NGSTTAICATGLRNLGN 166
Q ENS + K+ N+TL + L+ V A TGL+N+GN
Sbjct: 108 PHQIQENSV------QDFKIPSNTTLKTPLVAVFDDLDIEADEEDELRARGLTGLKNIGN 161
Query: 167 TCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTL 226
TC+MNA LQ+LSN +F + + ++ D ++ + + K +
Sbjct: 162 TCYMNAALQALSNCPPLTQFFLDCGGL----------------ARTDKKPAICKSYLKLM 205
Query: 227 CALWQGSQT-AFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
LW S+ + P +LF + + P FRGY QQDA EF+R L+D LH EL+
Sbjct: 206 TELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELK 257
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 132 bits (331), Expect = 1e-30
Identities = 87/273 (31%), Positives = 130/273 (47%), Gaps = 46/273 (16%)
Query: 286 SAILQENSTLSA-SNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDI 344
S +L++ LSA S + +V++ IF G + + V CL C S + F DLSL I
Sbjct: 420 SYVLKKAQVLSAGSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
Query: 345 PSQ--FRSKRSKNQEN--------------------------------------GPVCSL 364
P + S +N GPV +L
Sbjct: 480 PGKEDLAKLHSAIYQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTL 539
Query: 365 RDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKV 424
DCL +F +EL +Y C +CKK + K + +LP++LC+HLKRF K+
Sbjct: 540 EDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKI 599
Query: 425 DTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATH--EGRW 482
+++V FPL GLD++ +L + S + YDL +V+ HHG+ GSGHY AY + G+W
Sbjct: 600 NSHVSFPLEGLDLRPFLAKECTS--QITTYDLLSVICHHGT-AGSGHYIAYCQNVINGQW 656
Query: 483 FHFNDSTVTLTDEETVVKAKAYILFYVEHQAKA 515
+ F+D VT E V A+ Y+LFY + +A
Sbjct: 657 YEFDDQYVTEVHETVVQNAEGYVLFYRKSSEEA 689
Score = 81.3 bits (199), Expect = 2e-15
Identities = 74/283 (26%), Positives = 119/283 (42%), Gaps = 50/283 (17%)
Query: 3 CPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCL--TCSSVHCGRYVNGHAKKH 60
CPHL S + + + C S + + W CL C V CG H+
Sbjct: 8 CPHLDSIGEVTKEDLLLKS---KGTCQSCGVTGPNLWACLQVACPYVGCGESFADHS--- 61
Query: 61 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKL-----GLVQKVR 115
T H +++K H + ++ +++ +CY C+ V + +L G K
Sbjct: 62 --------TIHAQAKK-----HNLTVNLTTFRLWCYACEKEVFLEQRLAAPLLGSSSKFS 108
Query: 116 EHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQ 175
E + A E+ + + L K G TG++NLGN+C+MNA LQ
Sbjct: 109 EQDSPPPSHPLKAVPIAVADEGESESEDDDL-KPRG------LTGMKNLGNSCYMNAALQ 161
Query: 176 SLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT 235
+LSN +F E + + K A L + ++K + +W +
Sbjct: 162 ALSNCPPLTQFFLECGGLVRTDKKPA----------------LCKSYQKLVSEVWHKKRP 205
Query: 236 AFS-PESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
++ P SL + + + P FRGY QQD EF+R L+D LH EL+
Sbjct: 206 SYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELK 248
>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 132 bits (331), Expect = 1e-30
Identities = 87/273 (31%), Positives = 130/273 (47%), Gaps = 46/273 (16%)
Query: 286 SAILQENSTLSA-SNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDI 344
S +L++ LSA S + +V++ IF G + + V CL C S + F DLSL I
Sbjct: 420 SYVLKKAQVLSAGSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
Query: 345 PSQ--FRSKRSKNQEN--------------------------------------GPVCSL 364
P + S +N GPV +L
Sbjct: 480 PGKEDLAKLHSAIYQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTL 539
Query: 365 RDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKV 424
DCL +F +EL +Y C +CKK + K + +LP++LC+HLKRF K+
Sbjct: 540 EDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKI 599
Query: 425 DTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATH--EGRW 482
+++V FPL GLD++ +L + S + YDL +V+ HHG+ GSGHY AY + G+W
Sbjct: 600 NSHVSFPLEGLDLRPFLAKECTS--QITTYDLLSVICHHGT-AGSGHYIAYCQNVINGQW 656
Query: 483 FHFNDSTVTLTDEETVVKAKAYILFYVEHQAKA 515
+ F+D VT E V A+ Y+LFY + +A
Sbjct: 657 YEFDDQYVTEVHETVVQNAEGYVLFYRKSSEEA 689
Score = 81.3 bits (199), Expect = 2e-15
Identities = 74/283 (26%), Positives = 119/283 (42%), Gaps = 50/283 (17%)
Query: 3 CPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCL--TCSSVHCGRYVNGHAKKH 60
CPHL S + + + C S + + W CL C V CG H+
Sbjct: 8 CPHLDSIGEVTKEDLLLKS---KGTCQSCGVTGPNLWACLQVACPYVGCGESFADHS--- 61
Query: 61 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKL-----GLVQKVR 115
T H +++K H + ++ +++ +CY C+ V + +L G K
Sbjct: 62 --------TIHAQAKK-----HNLTVNLTTFRLWCYACEKEVFLEQRLAAPLLGSSSKFS 108
Query: 116 EHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQ 175
E + A E+ + + L K G TG++NLGN+C+MNA LQ
Sbjct: 109 EQDSPPPSHPLKAVPIAVADEGESESEDDDL-KPRG------LTGMKNLGNSCYMNAALQ 161
Query: 176 SLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT 235
+LSN +F E + + K A L + ++K + +W +
Sbjct: 162 ALSNCPPLTQFFLECGGLVRTDKKPA----------------LCKSYQKLVSEVWHKKRP 205
Query: 236 AFS-PESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
++ P SL + + + P FRGY QQD EF+R L+D LH EL+
Sbjct: 206 SYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELK 248
>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 132 bits (331), Expect = 1e-30
Identities = 87/273 (31%), Positives = 130/273 (47%), Gaps = 46/273 (16%)
Query: 286 SAILQENSTLSA-SNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDI 344
S +L++ LSA S + +V++ IF G + + V CL C S + F DLSL I
Sbjct: 420 SYVLKKAQVLSAGSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
Query: 345 PSQ--FRSKRSKNQEN--------------------------------------GPVCSL 364
P + S +N GPV +L
Sbjct: 480 PGKEDLAKLHSAIYQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTL 539
Query: 365 RDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKV 424
DCL +F +EL +Y C +CKK + K + +LP++LC+HLKRF K+
Sbjct: 540 EDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKI 599
Query: 425 DTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAYATH--EGRW 482
+++V FPL GLD++ +L + S + YDL +V+ HHG+ GSGHY AY + G+W
Sbjct: 600 NSHVSFPLEGLDLRPFLAKECTS--QITTYDLLSVICHHGT-AGSGHYIAYCQNVINGQW 656
Query: 483 FHFNDSTVTLTDEETVVKAKAYILFYVEHQAKA 515
+ F+D VT E V A+ Y+LFY + +A
Sbjct: 657 YEFDDQYVTEVHETVVQNAEGYVLFYRKSSEEA 689
Score = 81.3 bits (199), Expect = 2e-15
Identities = 74/283 (26%), Positives = 119/283 (42%), Gaps = 50/283 (17%)
Query: 3 CPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCL--TCSSVHCGRYVNGHAKKH 60
CPHL S + + + C S + + W CL C V CG H+
Sbjct: 8 CPHLDSIGEVTKEDLLLKS---KGTCQSCGVTGPNLWACLQVACPYVGCGESFADHS--- 61
Query: 61 YEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKL-----GLVQKVR 115
T H +++K H + ++ +++ +CY C+ V + +L G K
Sbjct: 62 --------TIHAQAKK-----HNLTVNLTTFRLWCYACEKEVFLEQRLAAPLLGSSSKFS 108
Query: 116 EHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQ 175
E + A E+ + + L K G TG++NLGN+C+MNA LQ
Sbjct: 109 EQDSPPPSHPLKAVPIAVADEGESESEDDDL-KPRG------LTGMKNLGNSCYMNAALQ 161
Query: 176 SLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQT 235
+LSN +F E + + K A L + ++K + +W +
Sbjct: 162 ALSNCPPLTQFFLECGGLVRTDKKPA----------------LCKSYQKLVSEVWHKKRP 205
Query: 236 AFS-PESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
++ P SL + + + P FRGY QQD EF+R L+D LH EL+
Sbjct: 206 SYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELK 248
>gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo
sapiens]
Length = 559
Score = 130 bits (327), Expect = 3e-30
Identities = 103/365 (28%), Positives = 168/365 (46%), Gaps = 59/365 (16%)
Query: 147 LKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTY 206
L ++ A GL+N+GNTC++NA LQ L+ Y +T
Sbjct: 68 LPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLS----------REHSQTC 117
Query: 207 HTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMR 266
H R +G ++ + L +P + + F +Q+DAHEF+
Sbjct: 118 H-RHKGCMLCTMQAHITRAL----------HNPGHVIQPSQALAAGFHRGKQEDAHEFLM 166
Query: 267 YLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVNCLI 326
+ +D + + A L + + +K +T++ IFGG ++++ CL
Sbjct: 167 FTVDAM------------KKACLPGHKQVDHHSK-----DTTLIHQIFGGYWRSQIKCLH 209
Query: 327 CGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCH 386
C S FDP+LD++LDI + S++ L EEL+ Y C
Sbjct: 210 CHGISDTFDPYLDIALDIQA--------------AQSVQQALEQLVKPEELNGENAYHCG 255
Query: 387 KCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPEN 446
C ++ ++K + KVL L LKRF + NK+D V++P LDMK Y+ + N
Sbjct: 256 VCLQRAPASKTLTLHTSAKVLILVLKRF--SDVTGNKIDKNVQYP-ECLDMKLYMSQ-TN 311
Query: 447 SGPESCLYDLAAVVVHHGSGVGSGHYTAYA-THEGRWFHFNDSTVTLTDEETVVKAKAYI 505
SGP +Y L AV+VH G +GHY +Y EG+W+ +D+ VT + +V+ +AY+
Sbjct: 312 SGP--LVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYV 369
Query: 506 LFYVE 510
LFY++
Sbjct: 370 LFYIQ 374
>gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
Length = 339
Score = 129 bits (325), Expect = 5e-30
Identities = 102/321 (31%), Positives = 146/321 (45%), Gaps = 37/321 (11%)
Query: 159 TGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVE-LRNGKTAGRRTYHTRSQGDNNVS 217
TGL NLGNTC +NAI Q L +I LP VE GK + V+
Sbjct: 44 TGLWNLGNTCCVNAISQCLCSI---------LPLVEYFLTGKYITALQKFLLPSDCSEVA 94
Query: 218 LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQ 277
F + +W G SPE + + + P F QQDA EF+ +L+ LH L+
Sbjct: 95 TA--FAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALK 152
Query: 278 GGFNGVSRSAILQENSTLSASNKCC---INGASTVVTAIFGGILQNEVNCLICGTESRKF 334
SR ++ ST +CC I ++++T +F L + CL C + K
Sbjct: 153 KYH--YSRRRSYEKGST----QRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKN 206
Query: 335 DPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQKS 394
+ F SL IPS++ CSLRDCL+ F + L C C+ KQ++
Sbjct: 207 EVFTVFSLPIPSKYE------------CSLRDCLQCFFQQDALTWNNEIHCSFCETKQET 254
Query: 395 TKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLY 454
+ I K PK++ HLKRF + K+ T + +PL LD+ Y+ P+ Y
Sbjct: 255 AVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPK---Y 311
Query: 455 DLAAVVVHHGSGVGSGHYTAY 475
+L AVV H G + GHYTA+
Sbjct: 312 NLCAVVNHFGD-LDGGHYTAF 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,736,365
Number of Sequences: 37866
Number of extensions: 949129
Number of successful extensions: 2779
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 2198
Number of HSP's gapped (non-prelim): 246
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.