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Search of human proteins with 55769585
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55769585 HEF-like protein [Homo sapiens]
(786 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55769585 HEF-like protein [Homo sapiens] 1577 0.0
gi|5453680 neural precursor cell expressed, developmentally down... 266 7e-71
gi|215422375 neural precursor cell expressed, developmentally do... 265 2e-70
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 199 8e-51
gi|78486553 neural precursor cell expressed, developmentally dow... 95 2e-19
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r... 92 1e-18
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 92 2e-18
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r... 91 5e-18
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r... 89 1e-17
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r... 89 1e-17
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 57 7e-08
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 51 5e-06
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 51 5e-06
gi|47132519 Ras association and pleckstrin homology domains 1 is... 51 5e-06
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 50 6e-06
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 50 6e-06
gi|182765466 FCH and double SH3 domains 2 [Homo sapiens] 50 6e-06
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 50 8e-06
gi|11321634 CD2-associated protein [Homo sapiens] 50 1e-05
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 49 2e-05
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] 48 4e-05
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s... 48 4e-05
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 46 2e-04
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 46 2e-04
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 45 2e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 45 3e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 45 3e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 45 3e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 45 3e-04
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom... 45 3e-04
>gi|55769585 HEF-like protein [Homo sapiens]
Length = 786
Score = 1577 bits (4083), Expect = 0.0
Identities = 786/786 (100%), Positives = 786/786 (100%)
Query: 1 MKGTGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQ 60
MKGTGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQ
Sbjct: 1 MKGTGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQ 60
Query: 61 GLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWA 120
GLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWA
Sbjct: 61 GLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWA 120
Query: 121 EGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQH 180
EGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQH
Sbjct: 121 EGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQH 180
Query: 181 RGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKS 240
RGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKS
Sbjct: 181 RGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKS 240
Query: 241 EWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPM 300
EWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPM
Sbjct: 241 EWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPM 300
Query: 301 QKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVS 360
QKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVS
Sbjct: 301 QKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVS 360
Query: 361 QAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDD 420
QAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDD
Sbjct: 361 QAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDD 420
Query: 421 SSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIH 480
SSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIH
Sbjct: 421 SSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIH 480
Query: 481 RSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNR 540
RSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNR
Sbjct: 481 RSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNR 540
Query: 541 NWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQL 600
NWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQL
Sbjct: 541 NWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQL 600
Query: 601 TPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQP 660
TPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQP
Sbjct: 601 TPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQP 660
Query: 661 SSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTL 720
SSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTL
Sbjct: 661 SSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTL 720
Query: 721 CMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQ 780
CMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQ
Sbjct: 721 CMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQ 780
Query: 781 FRGTLG 786
FRGTLG
Sbjct: 781 FRGTLG 786
>gi|5453680 neural precursor cell expressed, developmentally
down-regulated 9 isoform 1 [Homo sapiens]
Length = 834
Score = 266 bits (679), Expect = 7e-71
Identities = 248/873 (28%), Positives = 390/873 (44%), Gaps = 147/873 (16%)
Query: 12 KALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL 71
K L+ARALYDN P+C++ELAF +GDILT++EQ+ EGWW C LHGRQG+ P NR+++L
Sbjct: 4 KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
Query: 72 ----TEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGP--QP 125
E A+ P GL + ++ YQVP P+ +Y+ S+ Q
Sbjct: 64 IGPMQETASSHEQP--ASGLMQQTFGQQKLYQVPN-PQAAPRDTIYQVPPSYQNQGIYQV 120
Query: 126 PTA------QVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQ 179
PT +VY+ PP+ R I + + ++T PVR T VY+ P++
Sbjct: 121 PTGHGTQEQEVYQV--PPSVQRSIGGTSGPHVGKKVIT---PVR----TGHGYVYEYPSR 171
Query: 180 HRGPVVLKEPEKQQLYDIPASPKKAGLHP-PDSQASGQGVPLISVTTLRRGGYSTLPNPQ 238
+ ++ +YDIP S G++ P S A G P+ SV
Sbjct: 172 Y----------QKDVYDIPPSHTTQGVYDIPPSSAKG---PVFSVPV----------GEI 208
Query: 239 KSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSR-SLTPQLNNN 297
K + +YD P + G ++ P ++ +E+ L F P R L P+ +
Sbjct: 209 KPQGVYDIPPTKGVYAI---PPSACRDEA---GLREKDYDFPPPMRQAGRPDLRPEGVYD 262
Query: 298 VP--MQKKLSLPEIPSYGFLVPRGTFPL---DEDVSYKVPSSFLIPRVEQQNTKPNIYDI 352
+P K Y +P P+ + +S P L V QN + YD+
Sbjct: 263 IPPTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQN---DAYDV 319
Query: 353 PKATSSVSQAGKELEKAKEVSENSAG----HNSSWFSRRTTSPSPEPDRLSGSSSDSRAS 408
P+ + + EKA + HN ++ + +RLS SS+ S S
Sbjct: 320 PRGVQFLEPPAETSEKANPQERDGVYDVPLHNPP-DAKGSRDLVDGINRLSFSSTGSTRS 378
Query: 409 IVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRF 468
+S+ S+TS+ +SS S+S K L LD D A E + LQ + V+ LM V+ WR
Sbjct: 379 NMST-SSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALVTTDWRC 437
Query: 469 RDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYR 528
Y+E +I+ I + D +E ++E+L F +G A L + L N+++ ++Q + +S++
Sbjct: 438 YGYMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQ 497
Query: 529 ILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLF 588
IL +T L+ +W L +L + QN DDL+RFVMVA+ +P+D K+ + + N LF
Sbjct: 498 ILSQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALF 557
Query: 589 KRNCE----KEETVQLTPNAEF----KCEKYIQPPQRETESHQKSTP---STKQREDEHS 637
+ K + + E+ + + P + ++H K+ P S +Q D S
Sbjct: 558 RPGPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKALPPGLSKEQAPDCSS 617
Query: 638 S---------------------------ELLKKNRANICGQNPGPL-------------- 656
S ELL+K NI QN L
Sbjct: 618 SDGSERSWMDDYDYVHLQGKEEFERQQKELLEKE--NIMKQNKMQLEHHQLSQFQLLEQE 675
Query: 657 IPQPSSQQTPERKPRLS--------------------EHCRLYFGALFKAISAFHGSLSS 696
I +P + KP S + C +F +L AI A +SS
Sbjct: 676 ITKPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSS 735
Query: 697 SQPAEI-ITQSKLVIMVGQKLV---DTLCMETQERDVRNEILRGSSHLCSLLKDVALATK 752
+QP I + SK VI+ KLV DTL + +D+RN+++ S+ LC LK + +ATK
Sbjct: 736 AQPPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQLCEQLKTIVMATK 795
Query: 753 NAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTL 785
A L YPS AL + + L ++ + F+ +L
Sbjct: 796 MAALHYPSTTALQEMVHQVTDLSRNAQLFKRSL 828
>gi|215422375 neural precursor cell expressed, developmentally
down-regulated 9 isoform 3 [Homo sapiens]
Length = 834
Score = 265 bits (676), Expect = 2e-70
Identities = 247/871 (28%), Positives = 389/871 (44%), Gaps = 147/871 (16%)
Query: 14 LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL-- 71
L+ARALYDN P+C++ELAF +GDILT++EQ+ EGWW C LHGRQG+ P NR+++L
Sbjct: 6 LMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLLIG 65
Query: 72 --TEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGP--QPPT 127
E A+ P GL + ++ YQVP P+ +Y+ S+ Q PT
Sbjct: 66 PMQETASSHEQP--ASGLMQQTFGQQKLYQVPN-PQAAPRDTIYQVPPSYQNQGIYQVPT 122
Query: 128 A------QVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHR 181
+VY+ PP+ R I + + ++T PVR T VY+ P+++
Sbjct: 123 GHGTQEQEVYQV--PPSVQRSIGGTSGPHVGKKVIT---PVR----TGHGYVYEYPSRY- 172
Query: 182 GPVVLKEPEKQQLYDIPASPKKAGLHP-PDSQASGQGVPLISVTTLRRGGYSTLPNPQKS 240
++ +YDIP S G++ P S A G P+ SV K
Sbjct: 173 ---------QKDVYDIPPSHTTQGVYDIPPSSAKG---PVFSVPV----------GEIKP 210
Query: 241 EWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSR-SLTPQLNNNVP 299
+ +YD P + G ++ P ++ +E+ L F P R L P+ ++P
Sbjct: 211 QGVYDIPPTKGVYAI---PPSACRDEA---GLREKDYDFPPPMRQAGRPDLRPEGVYDIP 264
Query: 300 --MQKKLSLPEIPSYGFLVPRGTFPL---DEDVSYKVPSSFLIPRVEQQNTKPNIYDIPK 354
K Y +P P+ + +S P L V QN + YD+P+
Sbjct: 265 PTCTKPAGKDLHVKYNCDIPGAAEPVARRHQSLSPNHPPPQLGQSVGSQN---DAYDVPR 321
Query: 355 ATSSVSQAGKELEKAKEVSENSAG----HNSSWFSRRTTSPSPEPDRLSGSSSDSRASIV 410
+ + EKA + HN ++ + +RLS SS+ S S +
Sbjct: 322 GVQFLEPPAETSEKANPQERDGVYDVPLHNPP-DAKGSRDLVDGINRLSFSSTGSTRSNM 380
Query: 411 SSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRD 470
S+ S+TS+ +SS S+S K L LD D A E + LQ + V+ LM V+ WR
Sbjct: 381 ST-SSTSSKESSLSASPAQDKRLFLDPDTAIERLQRLQQALEMGVSSLMALVTTDWRCYG 439
Query: 471 YLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRIL 530
Y+E +I+ I + D +E ++E+L F +G A L + L N+++ ++Q + +S++IL
Sbjct: 440 YMERHINEIRTAVDKVELFLKEYLHFVKGAVANAACLPELILHNKMKRELQRVEDSHQIL 499
Query: 531 LETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKR 590
+T L+ +W L +L + QN DDL+RFVMVA+ +P+D K+ + + N LF+
Sbjct: 500 SQTSHDLNECSWSLNILAINKPQNKCDDLDRFVMVAKTVPDDAKQLTTTINTNAEALFRP 559
Query: 591 NCE----KEETVQLTPNAEF----KCEKYIQPPQRETESHQKSTP---STKQREDEHSS- 638
K + + E+ + + P + ++H K+ P S +Q D SS
Sbjct: 560 GPGSLHLKNGPESIMNSTEYPHGGSQGQLLHPGDHKAQAHNKALPPGLSKEQAPDCSSSD 619
Query: 639 --------------------------ELLKKNRANICGQNPGPL--------------IP 658
ELL+K NI QN L I
Sbjct: 620 GSERSWMDDYDYVHLQGKEEFERQQKELLEKE--NIMKQNKMQLEHHQLSQFQLLEQEIT 677
Query: 659 QPSSQQTPERKPRLS--------------------EHCRLYFGALFKAISAFHGSLSSSQ 698
+P + KP S + C +F +L AI A +SS+Q
Sbjct: 678 KPVENDISKWKPSQSLPTTNSGVSAQDRQLLCFYYDQCETHFISLLNAIDALFSCVSSAQ 737
Query: 699 PAEI-ITQSKLVIMVGQKLV---DTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNA 754
P I + SK VI+ KLV DTL + +D+RN+++ S+ LC LK + +ATK A
Sbjct: 738 PPRIFVAHSKFVILSAHKLVFIGDTLTRQVTAQDIRNKVMNSSNQLCEQLKTIVMATKMA 797
Query: 755 VLTYPSPAALGHLQAEAEKLEQHTRQFRGTL 785
L YPS AL + + L ++ + F+ +L
Sbjct: 798 ALHYPSTTALQEMVHQVTDLSRNAQLFKRSL 828
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 199 bits (506), Expect = 8e-51
Identities = 228/903 (25%), Positives = 356/903 (39%), Gaps = 173/903 (19%)
Query: 14 LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73
+LA+ALYDN + DEL+F +GDI+T+LEQ +GWW C LHGRQG+ P NRL+IL
Sbjct: 6 VLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNRLKILVG 65
Query: 74 VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129
+ +P P G PA + P P P P Q S P P AQ
Sbjct: 66 MYDKKPAGPG-PGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
Query: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVL 186
+Y+ P P P ++T +F KQ T P P+ + +Y VP GP
Sbjct: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVPPGPGGPA-- 175
Query: 187 KEPEKQQLYDIPASPKKAGLH------PPDSQA---SGQGVPLISVTTLRRGGYSTLPNP 237
Q +Y +P S AG+ PP G P V R G
Sbjct: 176 -----QDIYQVPPS---AGMGHDIYQVPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAA 227
Query: 238 QKSEWIYDTP---VSPGKASVRNT-PLTSFAEESRPHALPSSSSTFYNPPSGRSRSL--- 290
Q + YD P ++PG + + P+ + + P+GR L
Sbjct: 228 QPEQDEYDIPRHLLAPGPQDIYDVPPVRGLLPSQYGQEVYDTPPMAVKGPNGRDPLLEVY 287
Query: 291 --TPQLNNNVPMQKKLSLPEI-PSYGFLVPRGTFPLDEDVSYKVPSSF------------ 335
P + +P ++ ++ PS VP G PL + +Y VP +F
Sbjct: 288 DVPPSVEKGLPPSNHHAVYDVPPSVSKDVPDG--PLLREETYDVPPAFAKAKPFDPARTP 345
Query: 336 LIPRVEQQNTKP--NIYDIP---------------KATSSVSQAGKELEKAKEVSENSAG 378
L+ ++ P ++YD+P ++ +E EV++
Sbjct: 346 LVLAAPPPDSPPAEDVYDVPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEVADGGVV 405
Query: 379 HNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLD 438
+ + P P + R S S+ ST S+ +SS +E L+L+
Sbjct: 406 DSGVY-------AVPPPAEREAPAEGKRLSASSTGSTRSSQSASSLEVAGPGRE-PLELE 457
Query: 439 VAKETVMALQHKVVSSVAGLM-----LFVSRKWRF-RDYLEANIDAIHRSTDHIEESVRE 492
VA E + LQ V ++VA L+ + WR + E + + + ++ +V E
Sbjct: 458 VAVEALARLQQGVSATVAHLLDLAGSAGATGSWRSPSEPQEPLVQDLQAAVAAVQSAVHE 517
Query: 493 FLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLD-NRNWPLEVLVTDS 551
L+FAR G A + +D L ++ Q+Q + + ++ L+ ++LD R L
Sbjct: 518 LLEFARSAVGNAAHTSDRALHAKLSRQLQKMEDVHQTLVAHGQALDAGRGGSGATL---- 573
Query: 552 VQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPNAEFKCEKY 611
+DL+R V +R +PED K+ AS + N LLF+R T P E +
Sbjct: 574 -----EDLDRLVACSRAVPEDAKQLASFLHGNASLLFRR------TKATAPGPEGGGTLH 622
Query: 612 IQPPQRETESHQKSTPST-------------------------------KQREDEHSSEL 640
P + + + PS K+ ++ EL
Sbjct: 623 PNPTDKTSSIQSRPLPSPPKFTSQDSPDGQYENSEGGWMEDYDYVHLQGKEEFEKTQKEL 682
Query: 641 LKKNRANICGQN------------------------------PGPLIPQPSSQQTPERKP 670
L+K G++ PL P + P +
Sbjct: 683 LEKGSITRQGKSQLELQQLKQFERLEQEVSRPIDHDLANWTPAQPLAPGRTGGLGPSDRQ 742
Query: 671 RL---SEHCRLYFGALFKAISAFHGSLSSSQPAEI-ITQSKLVIMVGQKLV---DTLCME 723
L E C L A+ AF +++++QP +I + SK VI+ KLV DTL +
Sbjct: 743 LLLFYLEQCEANLTTLTNAVDAFFTAVATNQPPKIFVAHSKFVILSAHKLVFIGDTLSRQ 802
Query: 724 TQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRG 783
+ DVR+++ S+ LC LL+ + TK A L YPSP+A + ++L T+QFR
Sbjct: 803 AKAADVRSQVTHYSNLLCDLLRGIVATTKAAALQYPSPSAAQDMVERVKELGHSTQQFRR 862
Query: 784 TLG 786
LG
Sbjct: 863 VLG 865
>gi|78486553 neural precursor cell expressed, developmentally
down-regulated 9 isoform 2 [Homo sapiens]
Length = 174
Score = 95.1 bits (235), Expect = 2e-19
Identities = 55/135 (40%), Positives = 77/135 (57%), Gaps = 15/135 (11%)
Query: 12 KALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL 71
K L+ARALYDN P+C++ELAF +GDILT++EQ+ EGWW C LHGRQG+ P NR+++L
Sbjct: 4 KNLMARALYDNVPECAEELAFRKGDILTVIEQNTGGLEGWWLCSLHGRQGIVPGNRVKLL 63
Query: 72 ----TEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGP--QP 125
E A+ P GL + ++ YQVP P+ +Y+ S+ Q
Sbjct: 64 IGPMQETASSHEQP--ASGLMQQTFGQQKLYQVPN-PQAAPRDTIYQVPPSYQNQGIYQV 120
Query: 126 PTA------QVYEFP 134
PT +VY+ P
Sbjct: 121 PTGHGTQEQEVYQVP 135
>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 353
Score = 92.4 bits (228), Expect = 1e-18
Identities = 67/194 (34%), Positives = 90/194 (46%), Gaps = 22/194 (11%)
Query: 14 LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73
+LA+ALYDN + DEL+F +GDI+T+LEQ +GWW C LHGRQG+ P N L+IL
Sbjct: 6 VLAKALYDNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIMPGNHLKILVG 65
Query: 74 VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129
+ +P P G PA + P P P P Q S P P AQ
Sbjct: 66 MYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
Query: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVL 186
+Y+ P P P ++T +F KQ T P P+ + +Y V GP
Sbjct: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVSPGPGGPA-- 175
Query: 187 KEPEKQQLYDIPAS 200
Q +Y +P S
Sbjct: 176 -----QDIYQVPPS 184
>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
sapiens]
Length = 561
Score = 91.7 bits (226), Expect = 2e-18
Identities = 101/341 (29%), Positives = 143/341 (41%), Gaps = 60/341 (17%)
Query: 7 MDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPES-EGWWKCLLHGRQGLAPA 65
M A LARALYDN + EL+F RGD+L +L++ +GW C LHG+QG+ PA
Sbjct: 1 MAIATSTQLARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQQGIVPA 60
Query: 66 NRLQILTEVAADRP-----CPPFLRGLEEAPASSEETYQVPTLPRP----PTPGPVYEQM 116
NR+++L A +P P AP S E +V +P P PT GP
Sbjct: 61 NRVKLLPAGPAPKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPARPCPTSGP----- 115
Query: 117 RSWAEGPQPPTAQ-VYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYD 175
GP PP+ +Y+ P + L+ P+ A+ P A L S YD
Sbjct: 116 ---PAGPCPPSPDLIYKIPRASGT-------QLAAPRDALEVYDVPPTA-LRVPSSGPYD 164
Query: 176 VPTQHRGPVVLKEP----EKQQLYDIPASPKKAGLHPPDSQASG---QGVPLISV-TTLR 227
P P+ P E YD+P +PK PD + G G P+ + + L+
Sbjct: 165 CPASFSHPLTRVAPQPPGEDDAPYDVPLTPKPPAELEPDLEWEGGREPGPPIYAAPSNLK 224
Query: 228 RGGYSTLPN----PQK----------SEWIYDTPVSPGKASVRNTP---LTSFAEESRPH 270
R S L N P++ E IYD P+ +A P L S +++
Sbjct: 225 RA--SALLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAPPSPEPPGALASHDQDTLAQ 282
Query: 271 ALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPS 311
L S PP R R + + + P+ L +PE PS
Sbjct: 283 LLARSP-----PPPHRPRLPSAESLSRRPL-PALPVPEAPS 317
Score = 44.7 bits (104), Expect = 3e-04
Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 4/110 (3%)
Query: 676 CRLYFGALFKAISAFHGSLSSSQPAEI-ITQSKLVIMVGQKLV---DTLCMETQERDVRN 731
C+ ++ AL A++A S ++QP + + SK V++ +LV DTL +R
Sbjct: 443 CQSHYSALQAAVAALMSSTQANQPPRLFVPHSKRVVVAAHRLVFVGDTLGRLAASAPLRA 502
Query: 732 EILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQF 781
++ + L L+ LA K A L YPS A+ + +L QF
Sbjct: 503 QVRAAGTALGQALRATVLAVKGAALGYPSSPAIQEMVQCVTELAGQALQF 552
>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 232
Score = 90.5 bits (223), Expect = 5e-18
Identities = 74/232 (31%), Positives = 102/232 (43%), Gaps = 32/232 (13%)
Query: 14 LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73
+LA+ALY N + DEL+F +GDI+T+LEQ +GWW C LHGRQG+ P N L+IL
Sbjct: 6 VLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
Query: 74 VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129
+ +P P G PA + P P P P Q S P P AQ
Sbjct: 66 MYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
Query: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPV-- 184
+Y+ P P P ++T +F KQ T P P+ + +Y V GP
Sbjct: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVSPGPGGPAQD 177
Query: 185 VLKEPEK----QQLYDIPAS-----------PKKAGLHPPDSQASGQGVPLI 221
+ + P +Y +P+S P KA P A GQ V ++
Sbjct: 178 IYQVPPSAGMGHDIYQVPSSMDTRSWEGTKPPAKANPSPLMGHARGQQVRMV 229
>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 224
Score = 89.4 bits (220), Expect = 1e-17
Identities = 66/194 (34%), Positives = 89/194 (45%), Gaps = 22/194 (11%)
Query: 14 LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73
+LA+ALY N + DEL+F +GDI+T+LEQ +GWW C LHGRQG+ P N L+IL
Sbjct: 6 VLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
Query: 74 VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129
+ +P P G PA + P P P P Q S P P AQ
Sbjct: 66 MYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
Query: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVL 186
+Y+ P P P ++T +F KQ T P P+ + +Y V GP
Sbjct: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVSPGPGGPA-- 175
Query: 187 KEPEKQQLYDIPAS 200
Q +Y +P S
Sbjct: 176 -----QDIYQVPPS 184
>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 368
Score = 89.4 bits (220), Expect = 1e-17
Identities = 66/194 (34%), Positives = 89/194 (45%), Gaps = 22/194 (11%)
Query: 14 LLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTE 73
+LA+ALY N + DEL+F +GDI+T+LEQ +GWW C LHGRQG+ P N L+IL
Sbjct: 6 VLAKALYVNVAESPDELSFRKGDIMTVLEQDTQGLDGWWLCSLHGRQGIVPGNHLKILVG 65
Query: 74 VAADRPCPPFLRGLEEAPASSEETYQVPTLP----RPPTPGPVYEQMRSWAEGPQPPTAQ 129
+ +P P G PA + P P P P Q S P P AQ
Sbjct: 66 MYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKAQ 124
Query: 130 --VYEFPDP-PTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVL 186
+Y+ P P P ++T +F KQ T P P+ + +Y V GP
Sbjct: 125 QGLYQVPGPSPQFQSPPAKQTSTFSKQ---TPHHP----FPSPATDLYQVSPGPGGPA-- 175
Query: 187 KEPEKQQLYDIPAS 200
Q +Y +P S
Sbjct: 176 -----QDIYQVPPS 184
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 57.0 bits (136), Expect = 7e-08
Identities = 93/381 (24%), Positives = 146/381 (38%), Gaps = 52/381 (13%)
Query: 81 PPFLRGLEEAPASSEETY--QVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPT 138
P GL +P+SS T Q PT+ P P R+ + P PP+AQ P
Sbjct: 1071 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ-----SSPI 1125
Query: 139 SARIICEKTLSFPKQAILTL----PRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQL 194
A+ P Q + PRPV P Q P+ R P P +++
Sbjct: 1126 DAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA----PTRKEF 1181
Query: 195 YDIPA------------SPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTL-PNPQKSE 241
I A +PK G D+ Q P + GYST P
Sbjct: 1182 GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
Query: 242 WIYDTPVSPGKASV-RNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPM 300
+ P S +AS R TP E + S STF P + PQ + P
Sbjct: 1242 GVISAPQSHARASAGRLTP-----ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPA 1296
Query: 301 QKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVP---SSFLIPRVEQQNTKPNIYDIPKATS 357
Q +L P +P + G P E P SS +P + +++P + T+
Sbjct: 1297 Q-RLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLP--SEASSQPQV-----KTN 1348
Query: 358 SVSQAGKE----LEKAKEVSENSAGHNSSWFSRRTTS-PSPEPDRLSGSSSDSRASIVS- 411
+S +E ++ +++S N + + S +T+ P+P+P RL S ++++++S
Sbjct: 1349 GISDGKRESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSS 1408
Query: 412 -SCSTTSTDDSSSSSSEESAK 431
SC T + S S+E+ +
Sbjct: 1409 VSCMPTMPPIPARSQSQENMR 1429
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 50.8 bits (120), Expect = 5e-06
Identities = 55/246 (22%), Positives = 98/246 (39%), Gaps = 27/246 (10%)
Query: 17 RALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAA 76
R L+D P+ DELA RGD++ +L + E +GWW+ GR+G+ P N +
Sbjct: 187 RVLFDYQPEAPDELALRRGDVVKVLSK-TTEDKGWWEGECQGRRGVFPDNFV-------- 237
Query: 77 DRPCPPFLRGLEEAPASSEET-YQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPD 135
P PP + + S E + P P T P +++ + GP A+ P
Sbjct: 238 -LPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPS--KAKTSRTPS 294
Query: 136 PPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQ--VYDVPTQHRGPVVLKEPEKQQ 193
+ + + Q+ + + S P Q V +H PV ++
Sbjct: 295 RDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTP 354
Query: 194 LYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKA 253
+ D A+P++ P++ S + +P +P+P+K+ + D PG +
Sbjct: 355 MPDKTATPERP--PAPENAPSSKKIP----------APDKVPSPEKTLTLGDKASIPGNS 402
Query: 254 SVRNTP 259
+ P
Sbjct: 403 TSGKIP 408
Score = 39.3 bits (90), Expect = 0.014
Identities = 87/386 (22%), Positives = 145/386 (37%), Gaps = 84/386 (21%)
Query: 24 PDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL------------ 71
P+ +DEL G+I+ ++++ +GWW +G+ G P+N +++L
Sbjct: 96 PEQADELKLQAGEIVEMIKEI---EDGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDM 152
Query: 72 TEVAADRPCPPFLRGLE-EAP------ASSEETYQVPTLPRPPTP-------GPVYEQM- 116
V+ PP L L ++P S E Y+V +P P G V + +
Sbjct: 153 PSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLS 212
Query: 117 -----RSWAEGPQPPTAQVYEFPD-----PPTSARIICEKTLSFPKQAILTLPRPV--RA 164
+ W EG V FPD PP +++ K +S + A + P+ + +
Sbjct: 213 KTTEDKGWWEGECQGRRGV--FPDNFVLPPPPIKKLVPRKVVS-RESAPIKEPKKLMPKT 269
Query: 165 SLPTLPSQVYDVPTQHRGPVVLK-----EPEKQQLYDIPASP----KKAGLHPPDSQASG 215
SLPT V + T GP K + Q+L + P + G + P + S
Sbjct: 270 SLPT----VKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSK 325
Query: 216 QGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESR----PHA 271
P + + +S +P K+ + TP+ A+ P A S+ P
Sbjct: 326 TQTPQQRSVSSQEEEHS---SPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDK 382
Query: 272 LPSSSSTFY---------NPPSGR--SRSLTPQLNNNVPMQKKLSLPE---IPSYGFLV- 316
+PS T N SG+ + P V + K S+PE IP V
Sbjct: 383 VPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVD 442
Query: 317 ----PRGTFPLDEDVSYKVPSSFLIP 338
P F ++E + + P +P
Sbjct: 443 KPSTPERVFSVEESPALEAPPMDKVP 468
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 50.8 bits (120), Expect = 5e-06
Identities = 55/246 (22%), Positives = 98/246 (39%), Gaps = 27/246 (10%)
Query: 17 RALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAA 76
R L+D P+ DELA RGD++ +L + E +GWW+ GR+G+ P N +
Sbjct: 76 RVLFDYQPEAPDELALRRGDVVKVLSK-TTEDKGWWEGECQGRRGVFPDNFV-------- 126
Query: 77 DRPCPPFLRGLEEAPASSEET-YQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPD 135
P PP + + S E + P P T P +++ + GP A+ P
Sbjct: 127 -LPPPPIKKLVPRKVVSRESAPIKEPKKLMPKTSLPTVKKLATATTGPS--KAKTSRTPS 183
Query: 136 PPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQ--VYDVPTQHRGPVVLKEPEKQQ 193
+ + + Q+ + + S P Q V +H PV ++
Sbjct: 184 RDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHSSPVKAPSVKRTP 243
Query: 194 LYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKA 253
+ D A+P++ P++ S + +P +P+P+K+ + D PG +
Sbjct: 244 MPDKTATPERP--PAPENAPSSKKIP----------APDKVPSPEKTLTLGDKASIPGNS 291
Query: 254 SVRNTP 259
+ P
Sbjct: 292 TSGKIP 297
Score = 31.2 bits (69), Expect = 3.9
Identities = 81/361 (22%), Positives = 131/361 (36%), Gaps = 81/361 (22%)
Query: 49 EGWWKCLLHGRQGLAPANRLQIL------------TEVAADRPCPPFLRGLE-EAP---- 91
+GWW +G+ G P+N +++L V+ PP L L ++P
Sbjct: 7 DGWWLGKKNGQLGAFPSNFVELLDSGPPSLGNPDMPSVSPGPQRPPKLSSLAYDSPPDYL 66
Query: 92 --ASSEETYQVPTLPRPPTP-------GPVYEQM------RSWAEGPQPPTAQVYEFPD- 135
S E Y+V +P P G V + + + W EG V FPD
Sbjct: 67 QTVSHPEVYRVLFDYQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGV--FPDN 124
Query: 136 ----PPTSARIICEKTLSFPKQAILTLPRPV--RASLPTLPSQVYDVPTQHRGPVVLK-- 187
PP +++ K +S + A + P+ + + SLPT V + T GP K
Sbjct: 125 FVLPPPPIKKLVPRKVVS-RESAPIKEPKKLMPKTSLPT----VKKLATATTGPSKAKTS 179
Query: 188 ---EPEKQQLYDIPASP----KKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKS 240
+ Q+L + P + G + P + S P + + +S +P K+
Sbjct: 180 RTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEHS---SPVKA 236
Query: 241 EWIYDTPVSPGKASVRNTPLTSFAEESR----PHALPSSSSTFY---------NPPSGR- 286
+ TP+ A+ P A S+ P +PS T N SG+
Sbjct: 237 PSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKI 296
Query: 287 -SRSLTPQLNNNVPMQKKLSLPE---IPSYGFLV-----PRGTFPLDEDVSYKVPSSFLI 337
+ P V + K S+PE IP V P F ++E + + P +
Sbjct: 297 PAPDKVPTPEKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKV 356
Query: 338 P 338
P
Sbjct: 357 P 357
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 50.8 bits (120), Expect = 5e-06
Identities = 61/238 (25%), Positives = 92/238 (38%), Gaps = 18/238 (7%)
Query: 90 APASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLS 149
AP S++ V T PPTP P + QP Y P PPT + TL
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKK-----QPAFPASYIPPSPPTPPVPVPPPTL- 840
Query: 150 FPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPP 209
PKQ +P + L +PS V + +Q P E Q L +PA+ P
Sbjct: 841 -PKQQSF-CAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANV------AP 892
Query: 210 DSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIY-DTPVSPGKASVRNTPLTSFAEESR 268
S + + P +++ P P +S ++ P SP A P T+ +
Sbjct: 893 QSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDK 952
Query: 269 PHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPE--IPSYGFLVPRGTFPLD 324
+ P ++ + P G+ TPQ N+++ PE PS LV + T P +
Sbjct: 953 SGS-PGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAE 1009
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/229 (23%), Positives = 81/229 (35%), Gaps = 30/229 (13%)
Query: 100 VPTLPR---PPTPGPVYEQMRSWAEGPQ-------PPTAQVYEF--------PDPPTSAR 141
VP P PPTPG Q++ P PP ++++ P PP
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPP 768
Query: 142 IICEKTLSFPKQAILTLPRP--VRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPA 199
I P + ++T+P P + P + PT P K+P Y P+
Sbjct: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP-PVPPAKKQPAFPASYIPPS 827
Query: 200 SPKKAGLHPPDSQASGQGV-------PLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGK 252
P PP + Q PL V ++ + S P P + P+ P
Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887
Query: 253 ASV--RNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVP 299
A+V ++ P + +P ++P S F PP S P + VP
Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVP 936
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 50.4 bits (119), Expect = 6e-06
Identities = 22/61 (36%), Positives = 32/61 (52%)
Query: 18 ALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAAD 77
AL+D + DEL+F G+ +T+L + PE WW LHG++G P N + V
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQ 824
Query: 78 R 78
R
Sbjct: 825 R 825
Score = 30.8 bits (68), Expect = 5.1
Identities = 49/196 (25%), Positives = 68/196 (34%), Gaps = 16/196 (8%)
Query: 99 QVPTLPRPPTPGPVYEQMRSWA---EGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAI 155
Q T P+ PTP P + Q ++W EGP P ++ P+P + +
Sbjct: 427 QPQTQPQTPTPAPQHPQ-QTWPPVNEGPPKPPTELE--PEPEIEGLLTPVLEAGDVDEGP 483
Query: 156 LTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASG 215
+ P P LP + VP VL E + A PP +
Sbjct: 484 VARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQY 543
Query: 216 QGVPLISVTTLRRGGYST-LPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPS 274
Q +IS R GG P P+ S P++ G + R P P PS
Sbjct: 544 Q--QIISRLFHRHGGPGPGGPEPELS------PITEG-SEARAGPPAPAPPAPIPPPAPS 594
Query: 275 SSSTFYNPPSGRSRSL 290
SS P S RS+
Sbjct: 595 QSSPPEQPQSMEMRSV 610
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 50.4 bits (119), Expect = 6e-06
Identities = 22/61 (36%), Positives = 32/61 (52%)
Query: 18 ALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAAD 77
AL+D + DEL+F G+ +T+L + PE WW LHG++G P N + V
Sbjct: 765 ALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQ 824
Query: 78 R 78
R
Sbjct: 825 R 825
Score = 30.8 bits (68), Expect = 5.1
Identities = 49/196 (25%), Positives = 68/196 (34%), Gaps = 16/196 (8%)
Query: 99 QVPTLPRPPTPGPVYEQMRSWA---EGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAI 155
Q T P+ PTP P + Q ++W EGP P ++ P+P + +
Sbjct: 427 QPQTQPQTPTPAPQHPQ-QTWPPVNEGPPKPPTELE--PEPEIEGLLTPVLEAGDVDEGP 483
Query: 156 LTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASG 215
+ P P LP + VP VL E + A PP +
Sbjct: 484 VARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQY 543
Query: 216 QGVPLISVTTLRRGGYST-LPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPS 274
Q +IS R GG P P+ S P++ G + R P P PS
Sbjct: 544 Q--QIISRLFHRHGGPGPGGPEPELS------PITEG-SEARAGPPAPAPPAPIPPPAPS 594
Query: 275 SSSTFYNPPSGRSRSL 290
SS P S RS+
Sbjct: 595 QSSPPEQPQSMEMRSV 610
>gi|182765466 FCH and double SH3 domains 2 [Homo sapiens]
Length = 740
Score = 50.4 bits (119), Expect = 6e-06
Identities = 48/183 (26%), Positives = 83/183 (45%), Gaps = 19/183 (10%)
Query: 4 TGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLA 63
+G ++ +ALYD DEL+F G I+ IL + + +G+W+ +GR G+
Sbjct: 560 SGSLNGDASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFNGRIGVF 619
Query: 64 PANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGP 123
P+ ++ L+ A++ P++R ++ +P+ +LP P P+Y+Q S + P
Sbjct: 620 PSVLVEELS--ASENGDTPWMREIQISPSPKPHA----SLP----PLPLYDQPPS-SPYP 668
Query: 124 QPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLP-------RPVRASLPTLPSQVYDV 176
P FP P++ QA P RPVRA+ P P+Q +
Sbjct: 669 SPDKRSSLYFPRSPSANEKSLHAESPGFSQASRHTPETSYGKLRPVRAA-PPPPTQNHRR 727
Query: 177 PTQ 179
P +
Sbjct: 728 PAE 730
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 50.1 bits (118), Expect = 8e-06
Identities = 87/365 (23%), Positives = 141/365 (38%), Gaps = 62/365 (16%)
Query: 81 PPFLRGLEEAPASSEETY--QVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPT 138
P GL +P+SS T Q PT+ P P R+ + P PP+AQ
Sbjct: 1027 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ--------- 1077
Query: 139 SARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIP 198
S+ I + P++ +P+ P P V PT+ P
Sbjct: 1078 SSPIDAQPATPLPQK---DPAQPLEPKRPPPPRPVAP-PTR------------------P 1115
Query: 199 ASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTL-PNPQKSEWIYDTPVSPGKASV-R 256
A P++ PP Q P + GYST P + P S +AS R
Sbjct: 1116 APPQR----PPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1171
Query: 257 NTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLV 316
TP E + S STF P + PQ + P Q +L P +P +
Sbjct: 1172 LTP-----ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ-RLQEPLVPVAAPMP 1225
Query: 317 PRGTFPLDEDVSYKVP---SSFLIPRVEQQNTKPNIYDIPKATSSVSQAGKE----LEKA 369
G P E P SS +P + +++P + T+ +S +E ++
Sbjct: 1226 QSGPQPNLETPPQPPPRSRSSHSLP--SEASSQPQV-----KTNGISDGKRESPLKIDPF 1278
Query: 370 KEVSENSAGHNSSWFSRRTTS-PSPEPDRLSGSSSDSRASIVS--SCSTTSTDDSSSSSS 426
+++S N + + S +T+ P+P+P RL S ++++++S SC T + S S
Sbjct: 1279 EDLSFNLLAVSKAQLSVQTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTMPPIPARSQS 1338
Query: 427 EESAK 431
+E+ +
Sbjct: 1339 QENMR 1343
>gi|11321634 CD2-associated protein [Homo sapiens]
Length = 639
Score = 49.7 bits (117), Expect = 1e-05
Identities = 40/141 (28%), Positives = 63/141 (44%), Gaps = 13/141 (9%)
Query: 28 DELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAADRPCPPFLRGL 87
DEL F G+I+ ++ + E+ GWW+ L+G++G+ P N + E+ D P P
Sbjct: 286 DELTFKEGEIIHLISKETGEA-GWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPP 344
Query: 88 EEAPA------SSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSA- 140
+APA ++E+ Y P EQ S PQ P + P PPT A
Sbjct: 345 AKAPAPKPELIAAEKKY-FSLKPEEKDEKSTLEQKPSKPAAPQVPPKK----PTPPTKAS 399
Query: 141 RIICEKTLSFPKQAILTLPRP 161
++ +PK+ +P P
Sbjct: 400 NLLRSSGTVYPKRPEKPVPPP 420
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/90 (34%), Positives = 41/90 (45%), Gaps = 11/90 (12%)
Query: 17 RALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAA 76
+ L++ P DEL GDI+ I E+ EGWW L+ + GL P+N ++ L EV
Sbjct: 114 KVLFEYIPQNEDELELKVGDIIDINEE---VEEGWWSGTLNNKLGLFPSNFVKEL-EVTD 169
Query: 77 DRPCPPFLRGLEEAPASSEETYQVPTLPRP 106
D EA SE PT P P
Sbjct: 170 DGE-------THEAQDDSETVLAGPTSPIP 192
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/100 (34%), Positives = 50/100 (50%), Gaps = 6/100 (6%)
Query: 341 EQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSEN------SAGHNSSWFSRRTTSPSPE 394
E +++ + ++SS S +G E E +E +N + G N S S R SP+
Sbjct: 2556 ESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASS 2615
Query: 395 PDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELS 434
S SSS S +S SS S++S+ SSSSSS S+ S
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/74 (35%), Positives = 40/74 (54%)
Query: 357 SSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTT 416
+S S + + S +S+ +SS S ++S S S SSS S +S SS S+T
Sbjct: 2613 ASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 2672
Query: 417 STDDSSSSSSEESA 430
+ +DSS SS +E+A
Sbjct: 2673 TDEDSSCSSDDEAA 2686
Score = 40.8 bits (94), Expect = 0.005
Identities = 25/76 (32%), Positives = 41/76 (53%)
Query: 355 ATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCS 414
A+ + S + + S +S+ +SS S ++S S S SSS S +S SS S
Sbjct: 2610 ASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2669
Query: 415 TTSTDDSSSSSSEESA 430
+++TD+ SS SS++ A
Sbjct: 2670 SSTTDEDSSCSSDDEA 2685
Score = 39.3 bits (90), Expect = 0.014
Identities = 24/75 (32%), Positives = 42/75 (56%)
Query: 356 TSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCST 415
+++ S+A + S +S+ +SS S ++S S S SSS S +S SS S+
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
Query: 416 TSTDDSSSSSSEESA 430
+S+ SSSS+++E +
Sbjct: 2663 SSSSSSSSSTTDEDS 2677
Score = 38.9 bits (89), Expect = 0.019
Identities = 26/70 (37%), Positives = 38/70 (54%)
Query: 369 AKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEE 428
A S +S+ +SS S ++S S S SSS S +S SS S++S+ SSSSSS
Sbjct: 2613 ASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 2672
Query: 429 SAKELSLDLD 438
+ ++ S D
Sbjct: 2673 TDEDSSCSSD 2682
Score = 38.5 bits (88), Expect = 0.024
Identities = 27/84 (32%), Positives = 41/84 (48%)
Query: 357 SSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTT 416
S+ S + S +S+ +SS S ++S S S SSS S +S SS S++
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
Query: 417 STDDSSSSSSEESAKELSLDLDVA 440
S+ SSSSS+ + S D + A
Sbjct: 2663 SSSSSSSSSTTDEDSSCSSDDEAA 2686
Score = 37.0 bits (84), Expect = 0.071
Identities = 24/76 (31%), Positives = 40/76 (52%)
Query: 355 ATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCS 414
+ +S A + S +S+ +SS S ++S S S SSS S +S SS S
Sbjct: 2603 SAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2662
Query: 415 TTSTDDSSSSSSEESA 430
++S+ SSS++ E+S+
Sbjct: 2663 SSSSSSSSSTTDEDSS 2678
Score = 31.6 bits (70), Expect = 3.0
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 14/96 (14%)
Query: 353 PKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSD-------- 404
PK+ E+++ S +S+G +SS S ++ E + + D
Sbjct: 2541 PKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600
Query: 405 ------SRASIVSSCSTTSTDDSSSSSSEESAKELS 434
SRA+ +S S++S+ SSSSSS S+ S
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSS 2636
>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
Length = 352
Score = 47.8 bits (112), Expect = 4e-05
Identities = 24/55 (43%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 17 RALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL 71
RALYD P+ EL F GDI+T+ Q E W++ +LHG G P N ++IL
Sbjct: 296 RALYDFEPENEGELGFKEGDIITLTNQ---IDENWYEGMLHGHSGFFPINYVEIL 347
>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
sapiens]
Length = 486
Score = 47.8 bits (112), Expect = 4e-05
Identities = 25/56 (44%), Positives = 34/56 (60%), Gaps = 3/56 (5%)
Query: 16 ARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL 71
A ALYD + SDEL+F D++T +E EGWW+ HG GL PAN +++L
Sbjct: 433 AVALYDYQGEGSDELSFDPDDVITDIEM---VDEGWWRGRCHGHFGLFPANYVKLL 485
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 45.8 bits (107), Expect = 2e-04
Identities = 20/56 (35%), Positives = 36/56 (64%), Gaps = 3/56 (5%)
Query: 19 LYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEV 74
+YD DELAF++G I+ +L + P+ WWK ++G+ GL P+N +++ T++
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKEDPD---WWKGEVNGQVGLFPSNYVKLTTDM 1215
Score = 36.6 bits (83), Expect = 0.093
Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 12 KALLARALYDNCPDCSDELAFSRGDILTILEQHVPESE----GWWKCLLHGRQGLAPANR 67
K + RALY DE+ GDI+ + + V ES+ GW L G+ G PAN
Sbjct: 741 KVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANY 800
Query: 68 LQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPV 112
+ + E P P + APA P L TP P+
Sbjct: 801 AEKIPENEVPAPVKP-VTDSTSAPA--------PKLALRETPAPL 836
Score = 35.0 bits (79), Expect = 0.27
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 6/82 (7%)
Query: 12 KALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL 71
+ L A+ALY + L F++ D++T+LEQ + WW + G++G P + ++++
Sbjct: 914 EGLQAQALYPWRAKKDNHLNFNKNDVITVLEQ----QDMWWFGEVQGQKGWFPKSYVKLI 969
Query: 72 TEVAADRPCPPFLRGLEEAPAS 93
+ R G E+PAS
Sbjct: 970 S--GPIRKSTSMDSGSSESPAS 989
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 45.8 bits (107), Expect = 2e-04
Identities = 20/56 (35%), Positives = 36/56 (64%), Gaps = 3/56 (5%)
Query: 19 LYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEV 74
+YD DELAF++G I+ +L + P+ WWK ++G+ GL P+N +++ T++
Sbjct: 1163 MYDYTAQNDDELAFNKGQIINVLNKEDPD---WWKGEVNGQVGLFPSNYVKLTTDM 1215
Score = 36.6 bits (83), Expect = 0.093
Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 13/105 (12%)
Query: 12 KALLARALYDNCPDCSDELAFSRGDILTILEQHVPESE----GWWKCLLHGRQGLAPANR 67
K + RALY DE+ GDI+ + + V ES+ GW L G+ G PAN
Sbjct: 741 KVVYYRALYPFESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANY 800
Query: 68 LQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPV 112
+ + E P P + APA P L TP P+
Sbjct: 801 AEKIPENEVPAPVKP-VTDSTSAPA--------PKLALRETPAPL 836
Score = 35.0 bits (79), Expect = 0.27
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 6/82 (7%)
Query: 12 KALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQIL 71
+ L A+ALY + L F++ D++T+LEQ + WW + G++G P + ++++
Sbjct: 914 EGLQAQALYPWRAKKDNHLNFNKNDVITVLEQ----QDMWWFGEVQGQKGWFPKSYVKLI 969
Query: 72 TEVAADRPCPPFLRGLEEAPAS 93
+ R G E+PAS
Sbjct: 970 S--GPIRKSTSMDSGSSESPAS 989
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 45.4 bits (106), Expect = 2e-04
Identities = 63/238 (26%), Positives = 85/238 (35%), Gaps = 27/238 (11%)
Query: 81 PPFLRGLEEAPASSEETY--QVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPT 138
P GL +P+SS T Q PT+ P P R+ + P PP+AQ P
Sbjct: 1032 PSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ-----SSPI 1086
Query: 139 SARIICEKTLSFPKQAILTL----PRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQL 194
A+ P Q + PRPV P Q P+ R P P +++
Sbjct: 1087 DAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA----PTRKEF 1142
Query: 195 YDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTL-PNPQKSEWIYDTPVSPGKA 253
+PK G D+ Q P + GYST P + P S +A
Sbjct: 1143 ----GAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARA 1198
Query: 254 SV-RNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIP 310
S R TP E + S STF P + PQ + P Q +L P +P
Sbjct: 1199 SAGRLTP-----ESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQ-RLQEPLVP 1250
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 45.1 bits (105), Expect = 3e-04
Identities = 81/368 (22%), Positives = 131/368 (35%), Gaps = 64/368 (17%)
Query: 88 EEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQP-----PTAQVYEFPDP----PT 138
E AP + +E PT P+ P P E + +G P P + P P PT
Sbjct: 545 EPAPTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602
Query: 139 SAR----IICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQL 194
+ + C+K P T P + PT P + + P LKEP
Sbjct: 603 TTKEPTSTTCDKPA--PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP----- 655
Query: 195 YDIPASPKKAG---LHP-----PDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDT 246
P +PKK L P P S S + P TT + +T P + T
Sbjct: 656 --APTTPKKPAPKELAPTTTKGPTSTTSDKPAP----TTPKETAPTTPKEPAPT-----T 704
Query: 247 PVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGR---SRSLTPQLNNNVPMQKK 303
P P + P T+ +E S P ++ +P S TP+ N P +
Sbjct: 705 PKKPAPTTPETPPPTT-SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-- 761
Query: 304 LSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAG 363
P +P+ P T P + + + T+ ++ P+ T++ +
Sbjct: 762 ---PGVPT--TKTPAATKP------------EMTTTAKDKTTERDLRTTPETTTAAPKMT 804
Query: 364 KELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSS 423
KE E + S ++ TT+ P +++ + + A V++ T T
Sbjct: 805 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 864
Query: 424 SSSEESAK 431
+ EE+AK
Sbjct: 865 NKPEETAK 872
Score = 38.9 bits (89), Expect = 0.019
Identities = 48/234 (20%), Positives = 81/234 (34%), Gaps = 13/234 (5%)
Query: 88 EEAPASSEE-----TYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARI 142
E AP +++E T PT P+ P P + + + P P T + P A
Sbjct: 277 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336
Query: 143 ICEKTLSFPKQAILTLPR-----PVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDI 197
E + PK+ T P+ + PT P + T+ P KEP
Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396
Query: 198 PASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRN 257
P + K+ P ++++ S TT + +T P + P +P K
Sbjct: 397 PTTTKEPA--PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPT 453
Query: 258 TPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPS 311
TP ++ A + P + + +L P + + PE P+
Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 507
Score = 37.7 bits (86), Expect = 0.042
Identities = 52/257 (20%), Positives = 79/257 (30%), Gaps = 11/257 (4%)
Query: 58 GRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTL--PRPPTPGPVYEQ 115
G++ A Q + + +A + P + L + +E T + P L P+ PTP E
Sbjct: 166 GKEKTTSAKETQSIEKTSA-KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 224
Query: 116 MRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYD 175
+ + P P T + P T T S P P + PT P +
Sbjct: 225 ASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280
Query: 176 VPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLP 235
T+ P K P +PKK P + P T + T
Sbjct: 281 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTK 338
Query: 236 NPQKSEWIYDTPVSPGK--ASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQ 293
P + P +P K + P + +E P S T P+ + P
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 398
Query: 294 LNNNVPMQKKLSLPEIP 310
S P P
Sbjct: 399 TTKEPAPTTTKSAPTTP 415
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 45.1 bits (105), Expect = 3e-04
Identities = 81/368 (22%), Positives = 131/368 (35%), Gaps = 64/368 (17%)
Query: 88 EEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQP-----PTAQVYEFPDP----PT 138
E AP + +E PT P+ P P E + +G P P + P P PT
Sbjct: 586 EPAPTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643
Query: 139 SAR----IICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQL 194
+ + C+K P T P + PT P + + P LKEP
Sbjct: 644 TTKEPTSTTCDKPA--PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP----- 696
Query: 195 YDIPASPKKAG---LHP-----PDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDT 246
P +PKK L P P S S + P TT + +T P + T
Sbjct: 697 --APTTPKKPAPKELAPTTTKGPTSTTSDKPAP----TTPKETAPTTPKEPAPT-----T 745
Query: 247 PVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGR---SRSLTPQLNNNVPMQKK 303
P P + P T+ +E S P ++ +P S TP+ N P +
Sbjct: 746 PKKPAPTTPETPPPTT-SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-- 802
Query: 304 LSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAG 363
P +P+ P T P + + + T+ ++ P+ T++ +
Sbjct: 803 ---PGVPT--TKTPAATKP------------EMTTTAKDKTTERDLRTTPETTTAAPKMT 845
Query: 364 KELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSS 423
KE E + S ++ TT+ P +++ + + A V++ T T
Sbjct: 846 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 905
Query: 424 SSSEESAK 431
+ EE+AK
Sbjct: 906 NKPEETAK 913
Score = 38.9 bits (89), Expect = 0.019
Identities = 48/234 (20%), Positives = 81/234 (34%), Gaps = 13/234 (5%)
Query: 88 EEAPASSEE-----TYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARI 142
E AP +++E T PT P+ P P + + + P P T + P A
Sbjct: 318 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377
Query: 143 ICEKTLSFPKQAILTLPR-----PVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDI 197
E + PK+ T P+ + PT P + T+ P KEP
Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437
Query: 198 PASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRN 257
P + K+ P ++++ S TT + +T P + P +P K
Sbjct: 438 PTTTKEPA--PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPT 494
Query: 258 TPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPS 311
TP ++ A + P + + +L P + + PE P+
Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 548
Score = 37.7 bits (86), Expect = 0.042
Identities = 52/257 (20%), Positives = 79/257 (30%), Gaps = 11/257 (4%)
Query: 58 GRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTL--PRPPTPGPVYEQ 115
G++ A Q + + +A + P + L + +E T + P L P+ PTP E
Sbjct: 207 GKEKTTSAKETQSIEKTSA-KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 265
Query: 116 MRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYD 175
+ + P P T + P T T S P P + PT P +
Sbjct: 266 ASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321
Query: 176 VPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLP 235
T+ P K P +PKK P + P T + T
Sbjct: 322 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTK 379
Query: 236 NPQKSEWIYDTPVSPGK--ASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQ 293
P + P +P K + P + +E P S T P+ + P
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 439
Query: 294 LNNNVPMQKKLSLPEIP 310
S P P
Sbjct: 440 TTKEPAPTTTKSAPTTP 456
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 45.1 bits (105), Expect = 3e-04
Identities = 81/368 (22%), Positives = 131/368 (35%), Gaps = 64/368 (17%)
Query: 88 EEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQP-----PTAQVYEFPDP----PT 138
E AP + +E PT P+ P P E + +G P P + P P PT
Sbjct: 638 EPAPTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695
Query: 139 SAR----IICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQL 194
+ + C+K P T P + PT P + + P LKEP
Sbjct: 696 TTKEPTSTTCDKPA--PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP----- 748
Query: 195 YDIPASPKKAG---LHP-----PDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDT 246
P +PKK L P P S S + P TT + +T P + T
Sbjct: 749 --APTTPKKPAPKELAPTTTKGPTSTTSDKPAP----TTPKETAPTTPKEPAPT-----T 797
Query: 247 PVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGR---SRSLTPQLNNNVPMQKK 303
P P + P T+ +E S P ++ +P S TP+ N P +
Sbjct: 798 PKKPAPTTPETPPPTT-SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-- 854
Query: 304 LSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAG 363
P +P+ P T P + + + T+ ++ P+ T++ +
Sbjct: 855 ---PGVPT--TKTPAATKP------------EMTTTAKDKTTERDLRTTPETTTAAPKMT 897
Query: 364 KELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSS 423
KE E + S ++ TT+ P +++ + + A V++ T T
Sbjct: 898 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 957
Query: 424 SSSEESAK 431
+ EE+AK
Sbjct: 958 NKPEETAK 965
Score = 38.9 bits (89), Expect = 0.019
Identities = 48/234 (20%), Positives = 81/234 (34%), Gaps = 13/234 (5%)
Query: 88 EEAPASSEE-----TYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARI 142
E AP +++E T PT P+ P P + + + P P T + P A
Sbjct: 370 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429
Query: 143 ICEKTLSFPKQAILTLPR-----PVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDI 197
E + PK+ T P+ + PT P + T+ P KEP
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489
Query: 198 PASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRN 257
P + K+ P ++++ S TT + +T P + P +P K
Sbjct: 490 PTTTKEPA--PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPT 546
Query: 258 TPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPS 311
TP ++ A + P + + +L P + + PE P+
Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 600
Score = 37.7 bits (86), Expect = 0.042
Identities = 52/257 (20%), Positives = 79/257 (30%), Gaps = 11/257 (4%)
Query: 58 GRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTL--PRPPTPGPVYEQ 115
G++ A Q + + +A + P + L + +E T + P L P+ PTP E
Sbjct: 259 GKEKTTSAKETQSIEKTSA-KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 317
Query: 116 MRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYD 175
+ + P P T + P T T S P P + PT P +
Sbjct: 318 ASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 373
Query: 176 VPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLP 235
T+ P K P +PKK P + P T + T
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTK 431
Query: 236 NPQKSEWIYDTPVSPGK--ASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQ 293
P + P +P K + P + +E P S T P+ + P
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491
Query: 294 LNNNVPMQKKLSLPEIP 310
S P P
Sbjct: 492 TTKEPAPTTTKSAPTTP 508
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 45.1 bits (105), Expect = 3e-04
Identities = 81/368 (22%), Positives = 131/368 (35%), Gaps = 64/368 (17%)
Query: 88 EEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQP-----PTAQVYEFPDP----PT 138
E AP + +E PT P+ P P E + +G P P + P P PT
Sbjct: 679 EPAPTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736
Query: 139 SAR----IICEKTLSFPKQAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQL 194
+ + C+K P T P + PT P + + P LKEP
Sbjct: 737 TTKEPTSTTCDKPA--PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP----- 789
Query: 195 YDIPASPKKAG---LHP-----PDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDT 246
P +PKK L P P S S + P TT + +T P + T
Sbjct: 790 --APTTPKKPAPKELAPTTTKGPTSTTSDKPAP----TTPKETAPTTPKEPAPT-----T 838
Query: 247 PVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGR---SRSLTPQLNNNVPMQKK 303
P P + P T+ +E S P ++ +P S TP+ N P +
Sbjct: 839 PKKPAPTTPETPPPTT-SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-- 895
Query: 304 LSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAG 363
P +P+ P T P + + + T+ ++ P+ T++ +
Sbjct: 896 ---PGVPT--TKTPAATKP------------EMTTTAKDKTTERDLRTTPETTTAAPKMT 938
Query: 364 KELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSS 423
KE E + S ++ TT+ P +++ + + A V++ T T
Sbjct: 939 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 998
Query: 424 SSSEESAK 431
+ EE+AK
Sbjct: 999 NKPEETAK 1006
Score = 38.9 bits (89), Expect = 0.019
Identities = 48/234 (20%), Positives = 81/234 (34%), Gaps = 13/234 (5%)
Query: 88 EEAPASSEE-----TYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARI 142
E AP +++E T PT P+ P P + + + P P T + P A
Sbjct: 411 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470
Query: 143 ICEKTLSFPKQAILTLPR-----PVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDI 197
E + PK+ T P+ + PT P + T+ P KEP
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530
Query: 198 PASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRN 257
P + K+ P ++++ S TT + +T P + P +P K
Sbjct: 531 PTTTKEPA--PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-KEPAPT 587
Query: 258 TPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPS 311
TP ++ A + P + + +L P + + PE P+
Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 641
Score = 37.7 bits (86), Expect = 0.042
Identities = 52/257 (20%), Positives = 79/257 (30%), Gaps = 11/257 (4%)
Query: 58 GRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTL--PRPPTPGPVYEQ 115
G++ A Q + + +A + P + L + +E T + P L P+ PTP E
Sbjct: 300 GKEKTTSAKETQSIEKTSA-KDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEP 358
Query: 116 MRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRPVRASLPTLPSQVYD 175
+ + P P T + P T T S P P + PT P +
Sbjct: 359 ASTTPKEPTPTTIK----SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 414
Query: 176 VPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLP 235
T+ P K P +PKK P + P T + T
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPA--PTTPKEPAPTTPKEPTPTTPKEPAPTTK 472
Query: 236 NPQKSEWIYDTPVSPGK--ASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQ 293
P + P +P K + P + +E P S T P+ + P
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532
Query: 294 LNNNVPMQKKLSLPEIP 310
S P P
Sbjct: 533 TTKEPAPTTTKSAPTTP 549
>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 44.7 bits (104), Expect = 3e-04
Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 5/90 (5%)
Query: 8 DCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANR 67
D + L+ RA ++ DEL+FS+GD++ + E GWW+ L+GR G P+N
Sbjct: 3 DNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRV---EEGGWWEGTLNGRTGWFPSNY 59
Query: 68 LQILTEVAADRPCPPFLRGLEEAPASSEET 97
++ + A+++P P L+ P + T
Sbjct: 60 VREVK--ASEKPVSPKSGTLKSPPKGFDTT 87
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,393,140
Number of Sequences: 37866
Number of extensions: 1890555
Number of successful extensions: 9828
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 427
Number of HSP's that attempted gapping in prelim test: 7863
Number of HSP's gapped (non-prelim): 1692
length of query: 786
length of database: 18,247,518
effective HSP length: 110
effective length of query: 676
effective length of database: 14,082,258
effective search space: 9519606408
effective search space used: 9519606408
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.