BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|55749451 transcription elongation factor A (SII)-like 4 [Homo sapiens] (215 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|55749459 transcription elongation factor A (SII)-like 4 [Homo... 444 e-125 gi|55749442 transcription elongation factor A (SII)-like 4 [Homo... 444 e-125 gi|65505873 transcription elongation factor A (SII)-like 4 [Homo... 444 e-125 gi|55749451 transcription elongation factor A (SII)-like 4 [Homo... 444 e-125 gi|17933774 transcription elongation factor A (SII)-like 2 [Homo... 355 2e-98 gi|61175239 transcription elongation factor A (SII)-like 5 [Homo... 184 4e-47 gi|55749431 transcription elongation factor A (SII)-like 3 [Homo... 182 2e-46 gi|14249718 transcription elongation factor A (SII)-like 3 [Homo... 182 2e-46 gi|118600971 transcription elongation factor A (SII)-like 6 [Hom... 157 5e-39 gi|55743140 WW domain binding protein 5 [Homo sapiens] 63 2e-10 gi|55743147 WW domain binding protein 5 [Homo sapiens] 63 2e-10 gi|10047100 WW domain binding protein 5 [Homo sapiens] 63 2e-10 gi|55743145 WW domain binding protein 5 [Homo sapiens] 63 2e-10 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 60 1e-09 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 59 4e-09 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 53 2e-07 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 52 3e-07 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 52 3e-07 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 51 8e-07 gi|21361639 DIPB protein [Homo sapiens] 50 1e-06 gi|11225260 DNA topoisomerase I [Homo sapiens] 50 2e-06 gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform... 50 2e-06 gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 49 3e-06 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 49 3e-06 gi|157738619 smoothelin-like 1 [Homo sapiens] 49 4e-06 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 48 7e-06 gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 47 9e-06 gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 47 9e-06 gi|4557509 cylicin 2 [Homo sapiens] 47 9e-06 gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 47 1e-05 >gi|55749459 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 444 bits (1141), Expect = e-125 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV Sbjct: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 >gi|55749442 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 444 bits (1141), Expect = e-125 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV Sbjct: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 >gi|65505873 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 444 bits (1141), Expect = e-125 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV Sbjct: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 >gi|55749451 transcription elongation factor A (SII)-like 4 [Homo sapiens] Length = 215 Score = 444 bits (1141), Expect = e-125 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK Sbjct: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED Sbjct: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL Sbjct: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 Query: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV Sbjct: 181 WMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 >gi|17933774 transcription elongation factor A (SII)-like 2 [Homo sapiens] Length = 227 Score = 355 bits (911), Expect = 2e-98 Identities = 179/228 (78%), Positives = 195/228 (85%), Gaps = 14/228 (6%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEKL++ENEGM SNQGK++NEEQP E KPEV C LEDKKLENEG TEN GK EE LK Sbjct: 1 MEKLFNENEGMPSNQGKIDNEEQPPHEGKPEVACILEDKKLENEGNTENTGKRV-EEPLK 59 Query: 61 DKGKPESEGEAK-EGKSEREGESEMEGGSEREGKPEIEGK------------PESEGEPG 107 DK KPES G+AK EGKSER+G+SEM+GGS+ EGKPE G+ PESEGEP Sbjct: 60 DKEKPESAGKAKGEGKSERKGKSEMQGGSKTEGKPERGGRAEGEGEPDSEREPESEGEPE 119 Query: 108 SETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQD 167 SETRAAGKRPAEDD+PRKAKRKTNKGLA YLK+YKEAIHDMNFSNEDMIREFDNMA+V+D Sbjct: 120 SETRAAGKRPAEDDIPRKAKRKTNKGLAQYLKQYKEAIHDMNFSNEDMIREFDNMARVED 179 Query: 168 EKRKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRDIEDIPYV 215 ++RKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRD EDIPYV Sbjct: 180 KRRKSKQKLGAFLWMQRNLQDPFYPRGPREFRGGCRAPRRDTEDIPYV 227 >gi|61175239 transcription elongation factor A (SII)-like 5 [Homo sapiens] Length = 206 Score = 184 bits (468), Expect = 4e-47 Identities = 100/217 (46%), Positives = 143/217 (65%), Gaps = 13/217 (5%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEKLY ENEG N+ +E+E +P+DE E ++ K + E K + +GKT E + Sbjct: 1 MEKLYKENEGKPENERNLESEGKPEDEGSTE-----DEGKSDEEEKPDMEGKTECEGKRE 55 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 D+G+P EG+ ++ EG E +G SE E KP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 56 DEGEPGDEGQLED-----EGNQEKQGKSEGEDKPQSEGKPASQAKPESQPRAAEKRPAED 110 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 111 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 169 Query: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 WMQR++QDPF PRG R RG G ++D+ED+PYV Sbjct: 170 WMQRDVQDPFAPRGQRGVRGVRGGGRGQKDLEDVPYV 206 >gi|55749431 transcription elongation factor A (SII)-like 3 [Homo sapiens] Length = 200 Score = 182 bits (462), Expect = 2e-46 Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163 Query: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 WMQR++QDPF PRG R RG G +R + DIPY+ Sbjct: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200 >gi|14249718 transcription elongation factor A (SII)-like 3 [Homo sapiens] Length = 200 Score = 182 bits (462), Expect = 2e-46 Identities = 103/217 (47%), Positives = 143/217 (65%), Gaps = 19/217 (8%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK DE Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDVEGKTECEGKREDE---- 51 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 G+P EG+ ++ EG E +G SE EGKP+ EGKP S+ +P S+ RAA KRPAED Sbjct: 52 --GEPGDEGQLED-----EGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRPAED 104 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163 Query: 181 WMQRNLQDPFYPRGPREFRG--GCRAPRRDIEDIPYV 215 WMQR++QDPF PRG R RG G +R + DIPY+ Sbjct: 164 WMQRDVQDPFAPRGQRGVRGVRGGGRGQRGLHDIPYL 200 >gi|118600971 transcription elongation factor A (SII)-like 6 [Homo sapiens] Length = 183 Score = 157 bits (398), Expect = 5e-39 Identities = 87/190 (45%), Positives = 126/190 (66%), Gaps = 17/190 (8%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 MEK Y++NEG N+GK E+E +P DE K + E++K + EGKTE +GK K Sbjct: 1 MEKPYNKNEGNLENEGKPEDEVEPDDEGKSD-----EEEKPDAEGKTECEGKR------K 49 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAED 120 +G+P EG+ ++ +G E +G SE EGKP+ EGKP S+ +P + RAA KRPA D Sbjct: 50 AEGEPGDEGQLED-----KGSQEKQGKSEGEGKPQGEGKPASQAKPEGQPRAAEKRPAGD 104 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFL 180 VPRKAKRKT++G K+ +E + + + S+E+M+RE ++++ Q+E RK KQK+G F Sbjct: 105 YVPRKAKRKTDRGTDDSPKDSQEDLQERHLSSEEMMRECGDVSRAQEELRK-KQKMGGFH 163 Query: 181 WMQRNLQDPF 190 WMQR++QDPF Sbjct: 164 WMQRDVQDPF 173 >gi|55743140 WW domain binding protein 5 [Homo sapiens] Length = 104 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 7/108 (6%) Query: 84 MEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKE 143 M+ + EGKPE E +P+ E EP E + + E++ KAK + L L+E+KE Sbjct: 1 MKSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--KAKGTFRERLIQSLQEFKE 58 Query: 144 AIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLW-MQRNLQDPF 190 IH+ + SNEDM RE D + DE R+ + KL W + RN P+ Sbjct: 59 DIHNRHLSNEDMFREVDEI----DEIRRVRNKLIVMRWKVNRNHPYPY 102 Score = 33.9 bits (76), Expect = 0.11 Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 5/40 (12%) Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTE 48 EG N+ + ++EE+P+ E KPE E++KLE E K + Sbjct: 8 EGKPENESEPKHEEEPKPEEKPE-----EEEKLEEEAKAK 42 >gi|55743147 WW domain binding protein 5 [Homo sapiens] Length = 104 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 7/108 (6%) Query: 84 MEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKE 143 M+ + EGKPE E +P+ E EP E + + E++ KAK + L L+E+KE Sbjct: 1 MKSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--KAKGTFRERLIQSLQEFKE 58 Query: 144 AIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLW-MQRNLQDPF 190 IH+ + SNEDM RE D + DE R+ + KL W + RN P+ Sbjct: 59 DIHNRHLSNEDMFREVDEI----DEIRRVRNKLIVMRWKVNRNHPYPY 102 Score = 33.9 bits (76), Expect = 0.11 Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 5/40 (12%) Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTE 48 EG N+ + ++EE+P+ E KPE E++KLE E K + Sbjct: 8 EGKPENESEPKHEEEPKPEEKPE-----EEEKLEEEAKAK 42 >gi|10047100 WW domain binding protein 5 [Homo sapiens] Length = 104 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 7/108 (6%) Query: 84 MEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKE 143 M+ + EGKPE E +P+ E EP E + + E++ KAK + L L+E+KE Sbjct: 1 MKSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--KAKGTFRERLIQSLQEFKE 58 Query: 144 AIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLW-MQRNLQDPF 190 IH+ + SNEDM RE D + DE R+ + KL W + RN P+ Sbjct: 59 DIHNRHLSNEDMFREVDEI----DEIRRVRNKLIVMRWKVNRNHPYPY 102 Score = 33.9 bits (76), Expect = 0.11 Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 5/40 (12%) Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTE 48 EG N+ + ++EE+P+ E KPE E++KLE E K + Sbjct: 8 EGKPENESEPKHEEEPKPEEKPE-----EEEKLEEEAKAK 42 >gi|55743145 WW domain binding protein 5 [Homo sapiens] Length = 104 Score = 63.2 bits (152), Expect = 2e-10 Identities = 40/108 (37%), Positives = 58/108 (53%), Gaps = 7/108 (6%) Query: 84 MEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKE 143 M+ + EGKPE E +P+ E EP E + + E++ KAK + L L+E+KE Sbjct: 1 MKSCQKMEGKPENESEPKHEEEPKPEEKPEEEEKLEEEA--KAKGTFRERLIQSLQEFKE 58 Query: 144 AIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGAFLW-MQRNLQDPF 190 IH+ + SNEDM RE D + DE R+ + KL W + RN P+ Sbjct: 59 DIHNRHLSNEDMFREVDEI----DEIRRVRNKLIVMRWKVNRNHPYPY 102 Score = 33.9 bits (76), Expect = 0.11 Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 5/40 (12%) Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTE 48 EG N+ + ++EE+P+ E KPE E++KLE E K + Sbjct: 8 EGKPENESEPKHEEEPKPEEKPE-----EEEKLEEEAKAK 42 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 60.5 bits (145), Expect = 1e-09 Identities = 52/199 (26%), Positives = 82/199 (41%), Gaps = 6/199 (3%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61 E+ E + + E E++ + ER+ E + K + + + + D E D Sbjct: 317 ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSD 376 Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRP-AED 120 + K S K ERE E E E ERE + E E + E E E E KR ED Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436 Query: 121 DVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKR----KSKQKL 176 + +RK + L Y+E + + RE++ A+ ++E+R K ++L Sbjct: 437 EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL 496 Query: 177 GAFLW-MQRNLQDPFYPRG 194 FL + DP Y RG Sbjct: 497 KEFLEDYDDDRDDPKYYRG 515 Score = 37.4 bits (85), Expect = 0.010 Identities = 36/159 (22%), Positives = 72/159 (45%), Gaps = 7/159 (4%) Query: 18 MENEEQPQDERKPEVTCTLED-KKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKS 76 +E EE +D E++ + KKLE E + K + +E+ K++ + E E E + + Sbjct: 267 IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKER---QEIEKERRERERERERERERR 323 Query: 77 EREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAH 136 ERE E E E E+E + E E + + + + E R + D R+ NK + Sbjct: 324 EREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSR 383 Query: 137 YLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175 ++ ++ + E RE + + + E+ + +++ Sbjct: 384 SREKSRDRERERERERE---RERERERERERERERERER 419 Score = 32.3 bits (72), Expect = 0.31 Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 17/110 (15%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDE-----EMLKDKGKPESEGEAKE 73 ++ + P+ R + L D++ E E ++ + +E + L +G P+ + E + Sbjct: 505 DDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQR 564 Query: 74 GKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKR--PAEDD 121 ME +ER +P+I+ +PESE E + KR P E++ Sbjct: 565 ----------MEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 58.5 bits (140), Expect = 4e-09 Identities = 44/121 (36%), Positives = 60/121 (49%), Gaps = 13/121 (10%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKK-----LENEGKTENKGKTGDEEMLKD 61 E EG +GK E EE+ ++ E E+++ E EGK E +G+ G+ E + Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872 Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGE-PGSETRAAGKRPAED 120 +G+ E E E EG+ E EGE E G E EG EG+ E EGE G E GK E Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGE---GEEEEG----EGEGEEEGEGEGEEEEGEGKGEEEG 925 Query: 121 D 121 + Sbjct: 926 E 926 Score = 58.2 bits (139), Expect = 5e-09 Identities = 41/106 (38%), Positives = 55/106 (51%), Gaps = 4/106 (3%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61 E+ E EG +G+ E EE +E + E E ++ E E + E G+EE + Sbjct: 827 EEEEEEGEG-EEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEG 885 Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPG 107 +G+ E EGE +E + E EGE E EG E E E EGK E EGE G Sbjct: 886 EGEEEGEGEGEEEEGEGEGEEEGEGEGEEE---EGEGKGEEEGEEG 928 Score = 57.8 bits (138), Expect = 7e-09 Identities = 43/128 (33%), Positives = 65/128 (50%), Gaps = 5/128 (3%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E EG +G+ E EE+ + E + E E ++ E EGK E +G+ G+ E +++G E Sbjct: 882 EGEGEGEEEGEGEGEEE-EGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEG--E 938 Query: 67 SEGEAKEGKSEREGESEMEGGSER-EGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRK 125 EGE EG+ E E E E EG E EG+ E EG+ E E G G+ E++ + Sbjct: 939 GEGEDGEGEGEEE-EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE 997 Query: 126 AKRKTNKG 133 + +G Sbjct: 998 EGEEEGEG 1005 Score = 55.5 bits (132), Expect = 3e-08 Identities = 48/170 (28%), Positives = 80/170 (47%), Gaps = 12/170 (7%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E EG +G+ E+ E +E + E E ++ E EG+ E +G+ EE + + E Sbjct: 934 EEEG----EGEGEDGEGEGEEEEGE----WEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985 Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGE-PGSETRAAGKRPAEDDVPRK 125 EGE +E + E EGE E EG E EG+ E E + E EGE G E G+ E++ + Sbjct: 986 GEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGE---EEEGEEE 1042 Query: 126 AKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175 + + +G + +E + ++ E + ++ K+ SK K Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIK 1092 Score = 54.3 bits (129), Expect = 8e-08 Identities = 42/120 (35%), Positives = 58/120 (48%), Gaps = 19/120 (15%) Query: 7 ENEGMASNQGKMENE-EQPQDERKPEVTCTLEDKKLENEGKTENKGKTGD--EEMLKDKG 63 E E +GK E E E+ + ER+ E ++++ E K E +G G+ EE + +G Sbjct: 746 EEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRG 805 Query: 64 KPESE------GEAKEGKSEREGESEMEGGSEREG----------KPEIEGKPESEGEPG 107 + + E GE +EGK ERE E E G E EG + E EGK E EGE G Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865 Score = 54.3 bits (129), Expect = 8e-08 Identities = 42/127 (33%), Positives = 61/127 (48%), Gaps = 10/127 (7%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E EG +G+ E ++E + E ED E EG+ E G+EE + +G+ E Sbjct: 916 EGEGKGEEEGEEGEGEGEEEEGEGEG----EDG--EGEGEEEEGEWEGEEEEGEGEGEEE 969 Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKA 126 EGE +EG+ E E E G E EG E EG+ E EGE E G+ E +V + Sbjct: 970 GEGEGEEGEGEGEEEEGEGEGEEEEG--EEEGEEEGEGE--EEGEGEGEEEEEGEVEGEV 1025 Query: 127 KRKTNKG 133 + + +G Sbjct: 1026 EGEEGEG 1032 Score = 53.1 bits (126), Expect = 2e-07 Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 14/114 (12%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61 E+ E EG +G+ E E + ++E + EV +E ++ E EG+ E + G+E Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEER---- 1046 Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGK 115 E EGE +E + RE E E EGK + G+ E+E + G E + K Sbjct: 1047 ----EKEGEGEENRRNREEE------EEEEGKYQETGEEENERQDGEEYKKVSK 1090 Score = 51.6 bits (122), Expect = 5e-07 Identities = 44/135 (32%), Positives = 66/135 (48%), Gaps = 15/135 (11%) Query: 2 EKLYSENEGMASNQGK-MENE-EQPQDERKPEVTCTLEDK-----------KLENEGKTE 48 E+ E EG +G+ +E E E+ + ERK E E+K + E EG+ E Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGE 806 Query: 49 NKGKTGDEEMLK-DKGKPESEGEAKEGKSERE-GESEMEGGSEREGKPEIEGKPESEGEP 106 K + G+ E + ++GK E E E +EG+ E E GE E E G E + E +G+ E E Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866 Query: 107 GSETRAAGKRPAEDD 121 G E G+ E++ Sbjct: 867 GEEEGEEGEGEGEEE 881 Score = 51.2 bits (121), Expect = 6e-07 Identities = 40/134 (29%), Positives = 64/134 (47%), Gaps = 4/134 (2%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGK-TENKGKTGDEEMLK 60 EK +E E G+ + +++ + + E +E+ E G+ E +G +EE + Sbjct: 693 EKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKE 752 Query: 61 DKGKPESEGEAKEGKSER-EGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAE 119 +GK E EGE EG+ E+ EGE + E + +E K E EG + EGE ET G+ E Sbjct: 753 GEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG-DQGEGEE-EETEGRGEEKEE 810 Query: 120 DDVPRKAKRKTNKG 133 + + KG Sbjct: 811 GGEVEGGEVEEGKG 824 Score = 51.2 bits (121), Expect = 6e-07 Identities = 42/142 (29%), Positives = 61/142 (42%), Gaps = 12/142 (8%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKT-----GDEEMLKD 61 E EG +G+ E EE + + E E+++ E EG+ E +G+ G+EE + Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE---E 1017 Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSER----EGKPEIEGKPESEGEPGSETRAAGKRP 117 +G+ E E E +EG+ E E E E G ER EG+ + E E E G + Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEEN 1077 Query: 118 AEDDVPRKAKRKTNKGLAHYLK 139 D K KG Y K Sbjct: 1078 ERQDGEEYKKVSKIKGSVKYGK 1099 Score = 50.1 bits (118), Expect = 1e-06 Identities = 42/102 (41%), Positives = 58/102 (56%), Gaps = 15/102 (14%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E EG +G+ E EE+ + E E+++ E EG+ E +G+ G+EE + +GK E Sbjct: 875 EGEG-EEEEGEGEGEEEGEGEG--------EEEEGEGEGEEEGEGE-GEEE--EGEGKGE 922 Query: 67 SEGEAKEGK-SEREGESEMEGGSEREGKPEIEGKPESEGEPG 107 EGE EG+ E EGE E E G E EG+ E EG+ E E E G Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDG-EGEGEEE-EGEWEGEEEEG 962 Score = 48.9 bits (115), Expect = 3e-06 Identities = 39/121 (32%), Positives = 61/121 (50%), Gaps = 9/121 (7%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTG-----DEEMLKD 61 E E ++G+ E E + E+ E+ E KK + E + + + + G ++EM + Sbjct: 673 EREKGEKDKGRGEMERPGEGEK--ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEG 730 Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPE-SEGEPGSETRAAGKRPAED 120 + EGE +EG E E E E EG E EG+ E+EG+ E EGE E RA + E+ Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE-EVEGEREKEEGERKKEERAGKEEKGEE 789 Query: 121 D 121 + Sbjct: 790 E 790 Score = 48.9 bits (115), Expect = 3e-06 Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 12/124 (9%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E EG +G+ E EE +E E E+++ E EG+ E +G+ G+EE + +G+ E Sbjct: 851 EEEG--EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE-GEEEEGEGEGEEE 907 Query: 67 SEGEAKE----GKSEREGES-----EMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRP 117 EGE +E GK E EGE E E G E EG+ E G E G+ Sbjct: 908 GEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGE 967 Query: 118 AEDD 121 E + Sbjct: 968 EEGE 971 Score = 44.3 bits (103), Expect = 8e-05 Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 10/120 (8%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78 E E+ +D+ + E+ E +K E K E K + G+E+ K++ +G KE E Sbjct: 673 EREKGEKDKGRGEMERPGEGEK-ELAEKEEWKKRDGEEQEQKER----EQGHQKERNQEM 727 Query: 79 E--GESEMEGGSEREGKPEIEGKPESEG-EPGSETRAAGKRPAEDDVPRKAKR--KTNKG 133 E GE E G E EG E E + E EG E G G+R E+ +K +R K KG Sbjct: 728 EEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKG 787 Score = 32.3 bits (72), Expect = 0.31 Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 8/126 (6%) Query: 8 NEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPES 67 +EG A + G+ E+ + + + E + + + E + K K E ++ G+ E Sbjct: 637 SEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGE--MERPGEGEK 694 Query: 68 EGEAKEGKSEREGES----EMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVP 123 E KE +R+GE E E G ++E E+E E E G E G R E++ Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE--GDREEEEEKE 752 Query: 124 RKAKRK 129 + K + Sbjct: 753 GEGKEE 758 Score = 29.3 bits (64), Expect = 2.6 Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 4/96 (4%) Query: 42 ENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKP----EIE 97 E EG ++KG +E+ ++ + ++ K+E + + EGK E E Sbjct: 589 EKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAE 648 Query: 98 GKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKG 133 PE G+ E ++G +D+ K ++ +G Sbjct: 649 DGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRG 684 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 53.1 bits (126), Expect = 2e-07 Identities = 34/114 (29%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78 E EE + E + E ++K+ E + E K KT + E K+K + E + + K K + Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71 Query: 79 EGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNK 132 E E E E E E K E E + EG + + ++ E++ +K +RKT K Sbjct: 72 EEEREEEEEEEEEEKEEEE---KEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122 Score = 30.4 bits (67), Expect = 1.2 Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 20/116 (17%) Query: 60 KDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAE 119 K + + E E E + E+EG+ + + +R+ E E +T+ KR + Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRK-----------EKEKKKKTKETEKRKEK 55 Query: 120 DDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175 ++ +K KRK K +E +E E+ E + K + +RK K+K Sbjct: 56 EEEEKKRKRKRKKKKEEEEREEEE---------EEEEEEKEEEEKEEGRRRKKKKK 102 Score = 29.3 bits (64), Expect = 2.6 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 8/87 (9%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E EG + K + +E+ + ++ E E ++ E + K + K K +EE +++ + E Sbjct: 24 EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEE 83 Query: 67 SEGEAKE--------GKSEREGESEME 85 E E +E K +R + E E Sbjct: 84 EEKEEEEKEEGRRRKKKKKRRRKEEEE 110 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 52.4 bits (124), Expect = 3e-07 Identities = 44/130 (33%), Positives = 61/130 (46%), Gaps = 20/130 (15%) Query: 19 ENEEQPQDE------RKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAK 72 E EE+P+ E +K V T + K E K E +G+ +EE +D+G +A+ Sbjct: 494 EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE--EDEG--AKSDQAE 549 Query: 73 EGKSEREGESEMEGGSEREGK-------PEIEGKPESEGEPGSETRAAGKRPAED---DV 122 EG SE+EG SE E G + EG+ E E K E + E SE A + D + Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 609 Query: 123 PRKAKRKTNK 132 P KAK K Sbjct: 610 PEKAKSPVPK 619 Score = 43.5 bits (101), Expect = 1e-04 Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 11/128 (8%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61 EK+ + E K + E ++E EV + K+ E +T+ +GK +E K+ Sbjct: 716 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 775 Query: 62 K----GKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEG-----EPGSETRA 112 K G E EG K K R+ + + G E EGK E+E + + +G E G T Sbjct: 776 KAGGEGGSEEEGSDKGAKGSRKEDIAVNG--EVEGKEEVEQETKEKGSGREEEKGVVTNG 833 Query: 113 AGKRPAED 120 PA++ Sbjct: 834 LDLSPADE 841 Score = 41.6 bits (96), Expect = 5e-04 Identities = 47/213 (22%), Positives = 87/213 (40%), Gaps = 28/213 (13%) Query: 17 KMENEEQPQDERKPEVT----CTLEDKKLENEGKTENKGKTGDEEMLKDKGK-------- 64 K+E+E+ +E +T +++++K E + E + + +EE+ K Sbjct: 461 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV 520 Query: 65 PESEGEAKEGKSEREGESEMEGGSE---REGKPEIEG---KPESEGEPGSETRAAGKRPA 118 E EGE +E + + E E E EG EG E EG K E E E G A A Sbjct: 521 KEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEA 580 Query: 119 EDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGA 178 E +K + K+ + + +E + D + + + V+++ + K Sbjct: 581 EAKEEKKVEEKSEE-----VATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP- 634 Query: 179 FLWMQRNLQDPFYPRGPREFRGGCRAPRRDIED 211 ++ + P P+ P E +G P+ +E+ Sbjct: 635 ---VEEKGKSP-VPKSPVEEKGKSPVPKSPVEE 663 Score = 39.7 bits (91), Expect = 0.002 Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 12/129 (9%) Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESE 68 EG + +G E EE Q+E + E E+ + + E K E K EE+ K E Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS----EEVAT---KEELV 602 Query: 69 GEAKEGKSEREGESEMEGGSEREGKPEIEGKP-ESEGE---PGSETRAAGKRPA-EDDVP 123 +AK K E+ + E +GK + P E +G+ P S GK P + V Sbjct: 603 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 662 Query: 124 RKAKRKTNK 132 K K +K Sbjct: 663 EKGKSPVSK 671 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 52.4 bits (124), Expect = 3e-07 Identities = 44/130 (33%), Positives = 61/130 (46%), Gaps = 20/130 (15%) Query: 19 ENEEQPQDE------RKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAK 72 E EE+P+ E +K V T + K E K E +G+ +EE +D+G +A+ Sbjct: 118 EKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEE--EDEG--AKSDQAE 173 Query: 73 EGKSEREGESEMEGGSEREGK-------PEIEGKPESEGEPGSETRAAGKRPAED---DV 122 EG SE+EG SE E G + EG+ E E K E + E SE A + D + Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233 Query: 123 PRKAKRKTNK 132 P KAK K Sbjct: 234 PEKAKSPVPK 243 Score = 43.5 bits (101), Expect = 1e-04 Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 11/128 (8%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61 EK+ + E K + E ++E EV + K+ E +T+ +GK +E K+ Sbjct: 340 EKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKE 399 Query: 62 K----GKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEG-----EPGSETRA 112 K G E EG K K R+ + + G E EGK E+E + + +G E G T Sbjct: 400 KAGGEGGSEEEGSDKGAKGSRKEDIAVNG--EVEGKEEVEQETKEKGSGREEEKGVVTNG 457 Query: 113 AGKRPAED 120 PA++ Sbjct: 458 LDLSPADE 465 Score = 41.6 bits (96), Expect = 5e-04 Identities = 47/213 (22%), Positives = 87/213 (40%), Gaps = 28/213 (13%) Query: 17 KMENEEQPQDERKPEVT----CTLEDKKLENEGKTENKGKTGDEEMLKDKGK-------- 64 K+E+E+ +E +T +++++K E + E + + +EE+ K Sbjct: 85 KVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEV 144 Query: 65 PESEGEAKEGKSEREGESEMEGGSE---REGKPEIEG---KPESEGEPGSETRAAGKRPA 118 E EGE +E + + E E E EG EG E EG K E E E G A A Sbjct: 145 KEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEA 204 Query: 119 EDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQKLGA 178 E +K + K+ + + +E + D + + + V+++ + K Sbjct: 205 EAKEEKKVEEKSEE-----VATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP- 258 Query: 179 FLWMQRNLQDPFYPRGPREFRGGCRAPRRDIED 211 ++ + P P+ P E +G P+ +E+ Sbjct: 259 ---VEEKGKSP-VPKSPVEEKGKSPVPKSPVEE 287 Score = 39.7 bits (91), Expect = 0.002 Identities = 37/129 (28%), Positives = 54/129 (41%), Gaps = 12/129 (9%) Query: 9 EGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESE 68 EG + +G E EE Q+E + E E+ + + E K E K EE+ K E Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKS----EEVAT---KEELV 226 Query: 69 GEAKEGKSEREGESEMEGGSEREGKPEIEGKP-ESEGE---PGSETRAAGKRPA-EDDVP 123 +AK K E+ + E +GK + P E +G+ P S GK P + V Sbjct: 227 ADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 286 Query: 124 RKAKRKTNK 132 K K +K Sbjct: 287 EKGKSPVSK 295 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 50.8 bits (120), Expect = 8e-07 Identities = 49/208 (23%), Positives = 88/208 (42%), Gaps = 25/208 (12%) Query: 3 KLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDK 62 ++ + EG + + + E + +++RK E E ++ GK E KG+ EE + K Sbjct: 44 EIETRKEGKKERESERKKERREREKRKRE----REKERKRERGKKEKKGERKKEERERKK 99 Query: 63 GKPESEGEAKEGKSEREGESEME-GGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDD 121 + E E + E K +R+ + + E G + +EGK E E K E + E E + ++ Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGK-ERERKEERKREERKERERKKEEREKER 158 Query: 122 VPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNE------------DMIREFDNMAKVQDEK 169 ++ K++ K + +E KE E RE K ++E+ Sbjct: 159 ERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEER 218 Query: 170 RKSKQKLGAFLWMQRNLQDPFYPRGPRE 197 +K +QK W ++ RG RE Sbjct: 219 KKERQKDRQTNWREKE-------RGKRE 239 Score = 43.5 bits (101), Expect = 1e-04 Identities = 35/166 (21%), Positives = 79/166 (47%), Gaps = 14/166 (8%) Query: 10 GMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEG 69 G S + E E + + E K E E ++ + + E + + ++E +++GK E +G Sbjct: 33 GWQSEIREREREIETRKEGKKE----RESERKKERREREKRKREREKERKRERGKKEKKG 88 Query: 70 EAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRK 129 E K K ERE + +EG+ + + K + + E G ++ +R +++ R+ +++ Sbjct: 89 ERK--KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146 Query: 130 TNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175 + KE +E + E RE + + ++E+++ ++K Sbjct: 147 RER-----KKEEREKERE---RKERKKRERKQVGEKEEERKEKERK 184 Score = 42.7 bits (99), Expect = 2e-04 Identities = 37/133 (27%), Positives = 59/133 (44%), Gaps = 8/133 (6%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKG-KTGDEEMLK 60 +K + G S +GK E + ++ERK E E KK E E + E K K + + + Sbjct: 116 KKKEKKERGRTSKEGK---ERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172 Query: 61 DKGKPESEGEAKEGK----SEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKR 116 +K + E E KE K + +E + E E RE K E + K E + E + + + Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE 232 Query: 117 PAEDDVPRKAKRK 129 RK ++K Sbjct: 233 KERGKRERKERKK 245 Score = 40.0 bits (92), Expect = 0.001 Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 10/149 (6%) Query: 32 VTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSERE 91 V+C+ K G + E + +GK E E E K+ + ERE + + E+E Sbjct: 20 VSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERRERE---KRKREREKE 76 Query: 92 GKPEIEGKPESEGEPGSETRAAGKR-----PAEDDVPRKAKRKTNKGLAHYLKEYKEAIH 146 K E GK E +GE E R KR E + K K+K K KE KE Sbjct: 77 RKRE-RGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135 Query: 147 DMNFSNEDMIREFDNMAKVQDEKRKSKQK 175 E+ +E + + ++++R+ K++ Sbjct: 136 KEERKREER-KERERKKEEREKERERKER 163 Score = 38.9 bits (89), Expect = 0.003 Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 10/162 (6%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENK-----GKTGDE 56 EK G +G+ + EE+ + +R+ E E ++ E K E K K G E Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKE-NKEGEEKEKRKKKEKKERGRTSKEGKE 132 Query: 57 EMLKDKGKPES--EGEAKEGKSEREGESEMEGGSERE--GKPEIEGKPESEGEPGSETRA 112 K++ K E E E K+ + E+E E + ER+ G+ E E K + E R Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192 Query: 113 AGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNED 154 +R E + + +RK + K+ ++ N+ ++ Sbjct: 193 RKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234 >gi|21361639 DIPB protein [Homo sapiens] Length = 344 Score = 50.1 bits (118), Expect = 1e-06 Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 10/117 (8%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E G + K+E E + + E E+ + E E ++E + +T EE +D+ E Sbjct: 74 EGAGKEEAEVKVEQEREIESEAG-------EESESEEESESEEESET--EEESEDESDEE 124 Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVP 123 SE +++E + E E ESE E ++ EG+ E EG+ E+E E E +R A+ P Sbjct: 125 SEEDSEE-EMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCP 180 Score = 46.2 bits (108), Expect = 2e-05 Identities = 32/112 (28%), Positives = 58/112 (51%), Gaps = 4/112 (3%) Query: 37 EDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEI 96 +++++E+E E++ + E + + + ESE E+ E +SE + E EME E E + + Sbjct: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDE-ESEEDSEEEMEDEQESEAEEDN 145 Query: 97 EGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKT---NKGLAHYLKEYKEAI 145 + + ESE E +E + E + R AKRK L+ Y +E ++ I Sbjct: 146 QEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLI 197 Score = 39.7 bits (91), Expect = 0.002 Identities = 30/88 (34%), Positives = 51/88 (57%), Gaps = 10/88 (11%) Query: 6 SENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKP 65 SE+E + ++ + E EE+ +DE E + ED + E E + E++ + ++E +G+ Sbjct: 99 SESEEESESEEESETEEESEDESDEE---SEEDSEEEMEDEQESEAEEDNQE----EGES 151 Query: 66 ESEGEAKEGKSEREGESEMEGGSEREGK 93 E+EGE E +SE + E EME +ER K Sbjct: 152 EAEGET-EAESEFDPEIEME--AERVAK 176 >gi|11225260 DNA topoisomerase I [Homo sapiens] Length = 765 Score = 49.7 bits (117), Expect = 2e-06 Identities = 50/201 (24%), Positives = 86/201 (42%), Gaps = 22/201 (10%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78 E++++ E+ +D + +++ K + K K G E KDK K + + KE K Sbjct: 37 EHKKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKVRA 96 Query: 79 EGESEMEGGSER--EGKPEIEGKPESEG--EPGSETRAAGKRPAEDD----VPRKAKRKT 130 G+++++ E P+I+ +PE +G P E KRP ++D P+K K + Sbjct: 97 SGDAKIKKEKENGFSSPPQIKDEPEDDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTED 156 Query: 131 NKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKV--QDEKRKSKQKLGAFLWMQRNLQD 188 K KE K + + + D KV D K+K +K W + ++ Sbjct: 157 TK------KEKKRKLEEEEDGKLKKPKNKDKDKKVPEPDNKKKKPKKEEEQKW--KWWEE 208 Query: 189 PFYPRGPR----EFRGGCRAP 205 YP G + E +G AP Sbjct: 209 ERYPEGIKWKFLEHKGPVFAP 229 Score = 30.0 bits (66), Expect = 1.5 Identities = 34/164 (20%), Positives = 63/164 (38%), Gaps = 9/164 (5%) Query: 18 MENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSE 77 + N+ Q + + + + +DK + E + + K D E K + E K E Sbjct: 6 LHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKEKDREKSKHSNSEHKDSEKKH--KE 63 Query: 78 REGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAG----KRPAEDDVPRKAKRKTNKG 133 +E +G SE+ + E E + RA+G K+ E+ + K Sbjct: 64 KEKTKHKDGSSEKHKDKHKDRDKEKRKE--EKVRASGDAKIKKEKENGFSSPPQIKDEPE 121 Query: 134 LAHYLKEYKEAIHDMNFSNEDMIREF-DNMAKVQDEKRKSKQKL 176 Y KE I + ++ ++ K +D K++ K+KL Sbjct: 122 DDGYFVPPKEDIKPLKRPRDEDDADYKPKKIKTEDTKKEKKRKL 165 >gi|69354671 ATP-binding cassette, sub-family F, member 1 isoform a [Homo sapiens] Length = 845 Score = 49.7 bits (117), Expect = 2e-06 Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 16/153 (10%) Query: 19 ENEEQPQDERKPEVTCTLE----DKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEG 74 ++EE+ ++E+ P E +K + E + KGK G EE K K KP+++ A + Sbjct: 139 QSEEEEEEEKHPPKPAKPEKNRINKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDN 198 Query: 75 KSE-REGESEMEGGSEREGK---PEIEGKPESEGEPGSETRAAGKRPAED---DVPRKAK 127 + E +E E E ++GK + E E EGE E G+ A+D + +K K Sbjct: 199 EEEDKEEEIIKEKEPPKQGKEKAKKAEQGSEEEGEGEEEEEEGGESKADDPYAHLSKKEK 258 Query: 128 RKTNKGLAH-----YLKEYKEAIHDMNFSNEDM 155 +K K + + LK A +D + S +M Sbjct: 259 KKLKKQMEYERQVASLKAANAAENDFSVSQAEM 291 Score = 39.3 bits (90), Expect = 0.003 Identities = 36/185 (19%), Positives = 81/185 (43%), Gaps = 19/185 (10%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61 +K E E + + + + ++Q Q ++K + K ++++G+ + E LK Sbjct: 49 DKQAGEEEKVLKEKEQQQQQQQQQQKKKRDTRKGRRKKDVDDDGEEKEL-----MERLKK 103 Query: 62 KGKPESEGEAKEGKSEREGESEMEGGS--------EREGKPEIEGKPESEGEPGSETRAA 113 P S+ E + + G + +GG+ + E + E E P +P E Sbjct: 104 LSVPTSDEEDEVPAPKPRGGKKTKGGNVFAALIQDQSEEEEEEEKHPPKPAKP--EKNRI 161 Query: 114 GKRPAEDDVP----RKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEK 169 K +E+ P +K K + +KG A ++ ++ E++I+E + + +++ Sbjct: 162 NKAVSEEQQPALKGKKGKEEKSKGKAKPQNKFAALDNEEEDKEEEIIKEKEPPKQGKEKA 221 Query: 170 RKSKQ 174 +K++Q Sbjct: 222 KKAEQ 226 >gi|13540523 nucleosomal binding protein 1 [Homo sapiens] Length = 282 Score = 48.9 bits (115), Expect = 3e-06 Identities = 39/107 (36%), Positives = 53/107 (49%), Gaps = 12/107 (11%) Query: 2 EKLYSENEGMASNQGKMENE---EQPQDERKPEVTCTLEDKKLENEGKTENKGK-TGDEE 57 E + +G GK E E+ +DE++ ED+K +GK GK GD++ Sbjct: 168 EDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEE------EDRKETGDGKENEDGKEKGDKK 221 Query: 58 MLKDKGKPESEGEAKEGKSEREGESEMEGGSEREG-KPEIEGKPESE 103 KD E E E ++GK E EG +E E G E+E K E EGK E E Sbjct: 222 EGKDVKVKEDEKEREDGK-EDEGGNEEEAGKEKEDLKEEEEGKEEDE 267 Score = 46.2 bits (108), Expect = 2e-05 Identities = 39/118 (33%), Positives = 54/118 (45%), Gaps = 3/118 (2%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61 E+ +E +G A + K E E+ E K ED K + +GK GK G+ E K+ Sbjct: 134 EEDQNEEKGEAGKEDKDEKGEEDGKEDK-NGNEKGEDAKEKEDGKKGEDGK-GNGEDGKE 191 Query: 62 KGKPESEGE-AKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPA 118 KG+ E E E KE +E E E G ++EGK + E E E G E + A Sbjct: 192 KGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEA 249 Score = 45.4 bits (106), Expect = 4e-05 Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 12/174 (6%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGK----TENKGKTGDEEMLKDK 62 EN A+ +G E +E E K E ED++ +NE K E+K + G+E+ +DK Sbjct: 103 ENIEDATEKGG-EKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDK 161 Query: 63 GKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPG-SETRAAGKRPAEDD 121 E +AKE + ++GE G + + K E E + E E G + GK + Sbjct: 162 NGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKK 221 Query: 122 VPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175 + K K ++ KE ++ D + E+ +E +++ + ++ K + + K Sbjct: 222 EGKDVKVKEDE------KEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIK 269 Score = 43.1 bits (100), Expect = 2e-04 Identities = 44/191 (23%), Positives = 82/191 (42%), Gaps = 25/191 (13%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLK 60 +E+ Y+EN + G+ + E P E++ +E K+ E TE G+ + + Sbjct: 72 VEEDYNEN----AKNGEAKITEAPASEKE-----IVEVKEENIEDATEKGGEKKEAVAAE 122 Query: 61 DKGKPESEGEAKEGKSEREGESEMEGGSER---EGKPEIEGKPESE----------GEPG 107 K + E + E +E ++E +GE+ E E+ +GK + G + E GE G Sbjct: 123 VKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDG 182 Query: 108 SETRAAGKRPAEDDVPRKAKRKTNKGLAH---YLKEYKEAIHDMNFSNEDMIREFDNMAK 164 GK ED+ + +++T G + K K+ D+ ++ RE + Sbjct: 183 KGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDE 242 Query: 165 VQDEKRKSKQK 175 +E+ K+K Sbjct: 243 GGNEEEAGKEK 253 Score = 31.2 bits (69), Expect = 0.70 Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 3/79 (3%) Query: 7 ENEGMASNQGKMENEEQPQ--DERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGK 64 E + + GK ENE+ + D+++ + ED+K +GK + G + K+ K Sbjct: 199 EEDRKETGDGK-ENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLK 257 Query: 65 PESEGEAKEGKSEREGESE 83 E EG+ ++ E +G+ E Sbjct: 258 EEEEGKEEDEIKEDDGKKE 276 Score = 30.0 bits (66), Expect = 1.5 Identities = 43/179 (24%), Positives = 70/179 (39%), Gaps = 31/179 (17%) Query: 13 SNQGKMENEEQPQDERKPEVTCTLEDKKLE---NEGKTENKGKTGDEEMLKDKGKPESEG 69 S+ KM+ + +E + + K E E EN K G+ ++ + P SE Sbjct: 40 SSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNEN-AKNGEAKITE---APASEK 95 Query: 70 EAKEGKSEREGESEMEGGSEREG------------KPEIEGKPESEGEPGSETR-AAGKR 116 E E K E ++ +GG ++E K + E + E +GE G E + G+ Sbjct: 96 EIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEE 155 Query: 117 PAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175 ++D K KG KE + D + E D K +DEK + +K Sbjct: 156 DGKED-----KNGNEKGEDAKEKEDGKKGEDGKGNGE------DGKEKGEDEKEEEDRK 203 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 48.9 bits (115), Expect = 3e-06 Identities = 40/120 (33%), Positives = 62/120 (51%), Gaps = 9/120 (7%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E EG A Q + E E P+ E + + +E + E E + E++G E + + +PE Sbjct: 2089 EAEGEA--QPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEA--EGEAQPE 2144 Query: 67 SEG-EAKEGKSEREGESE--MEGGSEREGKPEIEG--KPESEGEPGSETRAAGKRPAEDD 121 SEG EA++ + E + ESE +E E +PE+EG PE+EGE E+ AE + Sbjct: 2145 SEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGE 2204 Score = 46.6 bits (109), Expect = 2e-05 Identities = 43/125 (34%), Positives = 63/125 (50%), Gaps = 22/125 (17%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E+EG+ + E E QP+ E +E ++ E E + E +G E + + +PE Sbjct: 2144 ESEGVEAQDA--EGEAQPESEG-------IEAQEAEEEAQPELEGVEAPEA--EGEAQPE 2192 Query: 67 SEG-EAKEGKSEREGESEMEG----GSEREGKPEIEG--KPESEGE--PGSETRAAGKRP 117 SEG EA E +E E + E+EG +E E +PE EG PE+EGE P SE G++ Sbjct: 2193 SEGIEAPE--AEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKK 2250 Query: 118 AEDDV 122 V Sbjct: 2251 GSPQV 2255 Score = 46.2 bits (108), Expect = 2e-05 Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 15/132 (11%) Query: 2 EKLYSENEGMASNQGKM------ENEEQPQDERKPEVTCTLEDKKLENEGKTENKG---- 51 E+ E EG + ++ E E QP+ E + +E ++ E E + E++ Sbjct: 1944 EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAP 2003 Query: 52 -KTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSET 110 G+ + +++ +PES+G + KSE E E+EG ++ K E + +PES+G E Sbjct: 2004 EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQ---KTEGDAQPESDGVEAPEA 2060 Query: 111 RAAGKRPAEDDV 122 + AE +V Sbjct: 2061 EEEAQE-AEGEV 2071 Score = 41.2 bits (95), Expect = 7e-04 Identities = 38/121 (31%), Positives = 52/121 (42%), Gaps = 8/121 (6%) Query: 9 EGMASNQGKMENEEQPQ-DERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPES 67 E +G+ EE Q +E K E E +LE +TE +G+ +E L++ + Sbjct: 1305 ETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGG 1364 Query: 68 EGEAKEGKSEREGESEMEGGSEREGKPE---IEGKPESEGEPGSETRAA----GKRPAED 120 EG +EG E + EGG + E E EG PE G E A GK ED Sbjct: 1365 EGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQED 1424 Query: 121 D 121 D Sbjct: 1425 D 1425 Score = 40.0 bits (92), Expect = 0.001 Identities = 41/149 (27%), Positives = 64/149 (42%), Gaps = 20/149 (13%) Query: 6 SENEGMASNQG---KMENEEQPQDE-----RKPEVTCTLEDKKLENEGKTENKGKTGDEE 57 SE E +G K E + QP+ + E E + E EG+ + + D + Sbjct: 2029 SEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQ 2088 Query: 58 MLKDKGKPESEG-EAKEGKSEREG-------ESEMEGGSEREG--KPEIEGK--PESEGE 105 + + +PESEG EA E + E + E+E E E EG PE EG+ PESEG Sbjct: 2089 EAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGV 2148 Query: 106 PGSETRAAGKRPAEDDVPRKAKRKTNKGL 134 + + +E ++A+ + L Sbjct: 2149 EAQDAEGEAQPESEGIEAQEAEEEAQPEL 2177 Score = 39.7 bits (91), Expect = 0.002 Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 15/131 (11%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKL---ENEGKTENKGKTGDEEMLKDKG 63 E+E + + + + E + + +D PE ++ + E + E + +T E L+ +G Sbjct: 1870 ESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEG 1929 Query: 64 K--PESEG----EAKEGKSEREGESEMEGG------SEREGKPEIEGKPESEGEPGSETR 111 + PESEG EA+E E EG+++ E +E E +PE E E E ++ Sbjct: 1930 EDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEA 1989 Query: 112 AAGKRPAEDDV 122 +P +DV Sbjct: 1990 EGEAQPESEDV 2000 Score = 38.5 bits (88), Expect = 0.004 Identities = 34/112 (30%), Positives = 52/112 (46%), Gaps = 11/112 (9%) Query: 7 ENEGMASNQGKMENEEQPQ--DERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGK 64 E EG A Q ++E E P+ +E +PE +E + E E + E++G+T E+ KG Sbjct: 2200 EAEGEA--QPELEGVEAPEAEEEAQPEPE-GVETPEAEGEAQPESEGETQGEK----KGS 2252 Query: 65 PESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKR 116 P+ +G+SE ES +R P G PGS+T + R Sbjct: 2253 PQVS--LGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSR 2302 Score = 37.7 bits (86), Expect = 0.007 Identities = 29/101 (28%), Positives = 47/101 (46%), Gaps = 14/101 (13%) Query: 25 QDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEM 84 QD + + +E + E E + E++G PE+EG+A+E + E + ESE Sbjct: 1824 QDPGQSDGAEGIEAPEAEGEAQPESEGVEA----------PEAEGDAQEAEGEAQPESED 1873 Query: 85 EGGSEREGKPEIEGK----PESEGEPGSETRAAGKRPAEDD 121 E EG+ + E + PE+E E E+ A AE + Sbjct: 1874 VEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKE 1914 Score = 35.8 bits (81), Expect = 0.028 Identities = 35/154 (22%), Positives = 61/154 (39%), Gaps = 18/154 (11%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLED-KKLENEGKTENKGKTGDEEML 59 +E+ EG + ++ EE +E E LE+ K+ E EG+ E + + + E Sbjct: 1303 LEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEET 1362 Query: 60 KDKGKPESEGEAKEGKSEREGESE---MEGGSEREGKPEI--------------EGKPES 102 +G E + +E K EG + +E G + EG PE +GK Sbjct: 1363 GGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQ 1422 Query: 103 EGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAH 136 E +P E A + + P + + + +H Sbjct: 1423 EDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSH 1456 Score = 35.4 bits (80), Expect = 0.037 Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 17/123 (13%) Query: 6 SENEGMASN-QGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGK 64 +E + MA +GK N E E E + + G+T +G +G E+ L Sbjct: 1763 AEGDAMAQEREGKTHNSETSAGSELGEAE--QEGEGISERGETGGQG-SGHEDNL----- 1814 Query: 65 PESEGEAKEGKSEREGESEMEGG-----SEREGKPEIEGKPESEGEPGSETRAAGKRPAE 119 +GEA G + G+S+ G +E E +PE EG E E ++ +P Sbjct: 1815 ---QGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPES 1871 Query: 120 DDV 122 +DV Sbjct: 1872 EDV 1874 Score = 35.4 bits (80), Expect = 0.037 Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 10/110 (9%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEG-EAKEGKSE 77 E E++P+ E E+ E EG+T+ + + + + +++ +PESE EA E + E Sbjct: 1928 EGEDEPESEGAEAQEA--EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVE 1985 Query: 78 REGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAK 127 + E EG ++ E + ++E PE+EGE A +P D V + K Sbjct: 1986 TQ---EAEGEAQPESE-DVEA-PEAEGEMQEAEEEA--QPESDGVEAQPK 2028 Score = 32.0 bits (71), Expect = 0.41 Identities = 25/72 (34%), Positives = 34/72 (47%), Gaps = 5/72 (6%) Query: 42 ENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGE---SEMEGGSEREGKPEIEG 98 + G E + G + + +DK E E EREG+ SE GSE G+ E EG Sbjct: 1736 QGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSEL-GEAEQEG 1794 Query: 99 KPESE-GEPGSE 109 + SE GE G + Sbjct: 1795 EGISERGETGGQ 1806 Score = 30.0 bits (66), Expect = 1.5 Identities = 22/91 (24%), Positives = 40/91 (43%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78 E E +++R L + ++ E + E + + E L+++ E + +EG E Sbjct: 1275 EAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEE 1334 Query: 79 EGESEMEGGSEREGKPEIEGKPESEGEPGSE 109 + E +E EG+ E E + E E G E Sbjct: 1335 GVQLEETKETEGEGQQEEEAQLEEIEETGGE 1365 >gi|157738619 smoothelin-like 1 [Homo sapiens] Length = 512 Score = 48.5 bits (114), Expect = 4e-06 Identities = 35/117 (29%), Positives = 52/117 (44%), Gaps = 12/117 (10%) Query: 4 LYSENEGMASNQGKMENEEQPQ--DERKPEVTCTLEDKKLEN----------EGKTENKG 51 L SE + + K E+ ++ D KPE T+E++ + E TE K Sbjct: 150 LASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKE 209 Query: 52 KTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGS 108 K DEE + K E EAK E +G+ E + G++ E + E + E EPGS Sbjct: 210 KATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGS 266 Score = 33.5 bits (75), Expect = 0.14 Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 2/135 (1%) Query: 1 MEKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKK-LENEGKTENKGKTGDEEML 59 ++++ E++ A + E E + +D K E T ++ + E K+E K E L Sbjct: 91 LDEVKVESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTL 150 Query: 60 KDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAE 119 + + E EAK ++ ++ + + E + K S+ E G + + P E Sbjct: 151 ASEKQKAEEKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETG-QRKECSTEPKE 209 Query: 120 DDVPRKAKRKTNKGL 134 +AK ++ K + Sbjct: 210 KATDEEAKAESQKAV 224 Score = 30.4 bits (67), Expect = 1.2 Identities = 32/136 (23%), Positives = 51/136 (37%), Gaps = 22/136 (16%) Query: 17 KMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGE--AKEG 74 K +EE + +K V + + E +GK E K +E K++ + E E + Sbjct: 210 KATDEEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSE 269 Query: 75 KSEREGESEMEGG-----SEREGKPEIEGKPESEGE------------PGSETRAAGKRP 117 + E++ E E EGG S E PE P EG +T + Sbjct: 270 EQEQDVEKEPEGGAGVIPSSPEEWPE---SPTGEGHNLSTDGLGPDCVASGQTSPSASES 326 Query: 118 AEDDVPRKAKRKTNKG 133 + DVP+ + G Sbjct: 327 SPSDVPQSPPESPSSG 342 Score = 29.6 bits (65), Expect = 2.0 Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 25/159 (15%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKT--ENKGKTGDE-------E 57 E++ A + KME +E E V+ ++ ++ G E KG G E Sbjct: 8 ESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETKGTAGKAINEGPPTE 67 Query: 58 MLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSE-------- 109 K + P +G + E + E G E++ S+RE GK ++E E E Sbjct: 68 SGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAG----GKEDAEAELKKEDGEKEETT 123 Query: 110 ---TRAAGKRPAEDDVPRKAKRKTNKGLAHYLK-EYKEA 144 G++ P++A+ K + + K E KEA Sbjct: 124 VGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEA 162 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 47.8 bits (112), Expect = 7e-06 Identities = 33/115 (28%), Positives = 57/115 (49%), Gaps = 4/115 (3%) Query: 17 KMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKE--- 73 K+++EE+ + K E + +++ E TE + ++E +++GK E GE +E Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496 Query: 74 GKSEREGESEMEGGS-EREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAK 127 G+ E + E S E+E K ++ + +S E S + K PAE P KAK Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK 551 Score = 44.7 bits (104), Expect = 6e-05 Identities = 39/162 (24%), Positives = 65/162 (40%), Gaps = 5/162 (3%) Query: 18 MENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSE 77 ++ EE+PQ+ + E E++K KTE K + EE K + E KE E Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883 Query: 78 REGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHY 137 + ES++E E + PE E E + K + +V +K Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943 Query: 138 LKEYKEAIHDMNFSNEDMIREFDNMAKV-----QDEKRKSKQ 174 E KEA + + E+ ++ + K +D+K SK+ Sbjct: 944 PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985 Score = 42.0 bits (97), Expect = 4e-04 Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 5/114 (4%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78 E + P + + PE + E K+ + K+ ++E K + +S +AK E Sbjct: 536 EEAKSPAEVKSPEKA----KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE- 590 Query: 79 EGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNK 132 E +S E S + K ++ + +S E S + K PAE P KAK T + Sbjct: 591 EAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKE 644 Score = 36.2 bits (82), Expect = 0.022 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 2/77 (2%) Query: 15 QGKMENEEQPQDERKPEVTCTLEDK--KLENEGKTENKGKTGDEEMLKDKGKPESEGEAK 72 + K ++ + E PE T E+K K E + KTE K K D+ + K+ KP++E K Sbjct: 937 KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996 Query: 73 EGKSEREGESEMEGGSE 89 ++++ E +E Sbjct: 997 SSSTDQKDSKPPEKATE 1013 Score = 33.9 bits (76), Expect = 0.11 Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 7/124 (5%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78 E + P + + P E+ K E K+ K K+ +E K K +S E +E KS Sbjct: 610 EEAKSPAEAKSP----VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP-EKEEAKSPE 664 Query: 79 EGESEM--EGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAH 136 + +S + E S + K ++ + +S + S + K P + P K + K+ + Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724 Query: 137 YLKE 140 +KE Sbjct: 725 PVKE 728 Score = 32.7 bits (73), Expect = 0.24 Identities = 28/121 (23%), Positives = 52/121 (42%), Gaps = 11/121 (9%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E++ A + + ++ P E++ +++ E KTE K D+ K+ KP Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKE-KTEVAKKEPDDAKAKEPSKP- 944 Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKA 126 E KE E++ E E+ KPE KP++E + + + K P++ + Sbjct: 945 --AEKKEAAPEKKDTKE-----EKAKKPE--EKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995 Query: 127 K 127 K Sbjct: 996 K 996 Score = 32.3 bits (72), Expect = 0.31 Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 8/105 (7%) Query: 17 KMENEEQPQDERKPEVTCTLED--------KKLENEGKTENKGKTGDEEMLKDKGKPESE 68 K+E +E + + K EV D K E + K T +E+ K + KP++E Sbjct: 913 KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972 Query: 69 GEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAA 113 +AKE E + E + K E +E +AA Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017 Score = 31.2 bits (69), Expect = 0.70 Identities = 32/160 (20%), Positives = 64/160 (40%), Gaps = 4/160 (2%) Query: 19 ENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSER 78 E + P+ + PE TL+ K E + + + ++ + +K K + E K + + Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARS-PADKFPEKAKSPVKEEVKSPEKAK 800 Query: 79 EGESEMEGGSERE--GKPEIEGKPESEGEPGS-ETRAAGKRPAEDDVPRKAKRKTNKGLA 135 E E+E K E++ + E +P + + K+ E+ P K + K Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSK 860 Query: 136 HYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQK 175 KEA ++ E +KV+ +K +++ K Sbjct: 861 KEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900 Score = 29.3 bits (64), Expect = 2.6 Identities = 29/116 (25%), Positives = 53/116 (45%), Gaps = 11/116 (9%) Query: 19 ENEEQPQDERKP--EVTCTLEDKK--LENEGKTENKGKTGDEEMLKDKGKPESEGEAKEG 74 E + P+ + P E T E K ++ E K+ K K+ ++ D PE++ AKE Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE- 772 Query: 75 KSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKT 130 E S + E+ P ++ + +S + S + K P E ++P+K + K+ Sbjct: 773 ----EARSPADKFPEKAKSP-VKEEVKSPEKAKSPLKEDAKAP-EKEIPKKEEVKS 822 >gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] Length = 755 Score = 47.4 bits (111), Expect = 9e-06 Identities = 48/159 (30%), Positives = 65/159 (40%), Gaps = 31/159 (19%) Query: 22 EQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGE 81 E+P DE+K E T ED EG +EN K E ++G PE E E EG +R E Sbjct: 423 EEPIDEKKFEKT---EDGGEFEEGASENNAKESSPEKEAEEGCPEKESE--EGCPKRGFE 477 Query: 82 SEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRK-AKRKTNKGLAHYLKE 140 EG P R +E+D P+K +K+KT K Sbjct: 478 GSCSQKESEEGNP--------------------VRGSEEDSPKKESKKKTLKNDCEENGL 517 Query: 141 YKEAIHDMNFSNEDMI-----REFDNMAKVQDEKRKSKQ 174 KE+ D+N +E+ + E D+ K DE KQ Sbjct: 518 AKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ 556 Score = 38.1 bits (87), Expect = 0.006 Identities = 46/173 (26%), Positives = 76/173 (43%), Gaps = 18/173 (10%) Query: 6 SENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLE-NEGKTENKGKTGDEEMLKDKGK 64 SE E + K +EE + E V DK+LE N+ + G E++L ++G Sbjct: 561 SEREFEENGLEKDLDEEGSEKELHENVL----DKELEENDSENSEFEDDGSEKVLDEEG- 615 Query: 65 PESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPR 124 SE E E E+E E E E+ E + K + E AA K+ E D Sbjct: 616 --SEREFDEDSDEKE---EEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADE 670 Query: 125 KAKRKTNKGLAHYLKEYKEAI-HDMNFSNEDMIREFDNMAKVQDEKRKSKQKL 176 K +++ KE ++A ++ ++E + + D+ K+ DE+ S +KL Sbjct: 671 KLFEESDD------KEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717 Score = 36.2 bits (82), Expect = 0.022 Identities = 48/197 (24%), Positives = 74/197 (37%), Gaps = 30/197 (15%) Query: 9 EGMASNQGKMENEEQPQDERKPEVTCT-------LEDKKLENEGKTENKGKTGDEEMLKD 61 EG + N K + E+ +E PE E + E + N + +E+ K Sbjct: 442 EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKK 501 Query: 62 KGKP-------ESEGEAKEGKSEREGESEMEGGSEREG------KPEIEGKPESEGEPGS 108 + K E G AKE + + ESE E G +E K E E + E GS Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561 Query: 109 ETRAAGKRPAEDDVPRKAKRK------TNKGLAHYLKEYKEAIHDMN---FSNEDMIREF 159 E R + E D+ + K +K L E E D + E REF Sbjct: 562 E-REFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREF 620 Query: 160 DNMAKVQDEKRKSKQKL 176 D + ++E+ + +K+ Sbjct: 621 DEDSDEKEEEEDTYEKV 637 >gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] Length = 755 Score = 47.4 bits (111), Expect = 9e-06 Identities = 48/159 (30%), Positives = 65/159 (40%), Gaps = 31/159 (19%) Query: 22 EQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGE 81 E+P DE+K E T ED EG +EN K E ++G PE E E EG +R E Sbjct: 423 EEPIDEKKFEKT---EDGGEFEEGASENNAKESSPEKEAEEGCPEKESE--EGCPKRGFE 477 Query: 82 SEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRK-AKRKTNKGLAHYLKE 140 EG P R +E+D P+K +K+KT K Sbjct: 478 GSCSQKESEEGNP--------------------VRGSEEDSPKKESKKKTLKNDCEENGL 517 Query: 141 YKEAIHDMNFSNEDMI-----REFDNMAKVQDEKRKSKQ 174 KE+ D+N +E+ + E D+ K DE KQ Sbjct: 518 AKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ 556 Score = 38.1 bits (87), Expect = 0.006 Identities = 46/173 (26%), Positives = 76/173 (43%), Gaps = 18/173 (10%) Query: 6 SENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLE-NEGKTENKGKTGDEEMLKDKGK 64 SE E + K +EE + E V DK+LE N+ + G E++L ++G Sbjct: 561 SEREFEENGLEKDLDEEGSEKELHENVL----DKELEENDSENSEFEDDGSEKVLDEEG- 615 Query: 65 PESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPR 124 SE E E E+E E E E+ E + K + E AA K+ E D Sbjct: 616 --SEREFDEDSDEKE---EEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADE 670 Query: 125 KAKRKTNKGLAHYLKEYKEAI-HDMNFSNEDMIREFDNMAKVQDEKRKSKQKL 176 K +++ KE ++A ++ ++E + + D+ K+ DE+ S +KL Sbjct: 671 KLFEESDD------KEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717 Score = 36.2 bits (82), Expect = 0.022 Identities = 48/197 (24%), Positives = 74/197 (37%), Gaps = 30/197 (15%) Query: 9 EGMASNQGKMENEEQPQDERKPEVTCT-------LEDKKLENEGKTENKGKTGDEEMLKD 61 EG + N K + E+ +E PE E + E + N + +E+ K Sbjct: 442 EGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKK 501 Query: 62 KGKP-------ESEGEAKEGKSEREGESEMEGGSEREG------KPEIEGKPESEGEPGS 108 + K E G AKE + + ESE E G +E K E E + E GS Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561 Query: 109 ETRAAGKRPAEDDVPRKAKRK------TNKGLAHYLKEYKEAIHDMN---FSNEDMIREF 159 E R + E D+ + K +K L E E D + E REF Sbjct: 562 E-REFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREF 620 Query: 160 DNMAKVQDEKRKSKQKL 176 D + ++E+ + +K+ Sbjct: 621 DEDSDEKEEEEDTYEKV 637 >gi|4557509 cylicin 2 [Homo sapiens] Length = 348 Score = 47.4 bits (111), Expect = 9e-06 Identities = 48/204 (23%), Positives = 91/204 (44%), Gaps = 40/204 (19%) Query: 2 EKLYSENEGMASNQGKMENEE------QPQDERKPEVTCTLEDKKLENEGK---TENKGK 52 EKL ++ + S +GK + E+ + +DE+ +DKK N+GK TE++G+ Sbjct: 153 EKLDAKKD---SKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGE 209 Query: 53 TGDEEMLKDKGKPES----------EGEAKEGKSEREGESEMEGGSE-----------RE 91 G E KGK +S + + K + +G+ + G E ++ Sbjct: 210 KGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKK 269 Query: 92 GKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFS 151 GK + + ++ + + + K+ A D + AK+ T K A K+ K+ + Sbjct: 270 GKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKN------A 323 Query: 152 NEDMIREFDNMAKVQDEKRKSKQK 175 +D ++ AK +DEK+ +K+K Sbjct: 324 KKDAKKDAKKNAK-KDEKKDAKKK 346 Score = 44.7 bits (104), Expect = 6e-05 Identities = 35/168 (20%), Positives = 79/168 (47%), Gaps = 7/168 (4%) Query: 7 ENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPE 66 E + A+ GK ++ Q + + + KK +GK KGK +E++ K + Sbjct: 106 EVDSKAAEIGKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGK--EEKLDAKKDSKK 163 Query: 67 SEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSETRAAGKRPAEDDVPRKA 126 + +A++GK + +GG++++ K + K +S S T + G++ + +K Sbjct: 164 GKKDAEKGKDSATESEDEKGGAKKDNKKD---KKDSNKGKDSATESEGEKGGTEKDSKKG 220 Query: 127 KRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKRKSKQ 174 K+ + KG ++ +A+ +ED ++ + + +D K+ +K+ Sbjct: 221 KKDSKKGKDSAIE--LQAVKADEKKDEDGKKDANKGDESKDAKKDAKE 266 Score = 40.4 bits (93), Expect = 0.001 Identities = 26/98 (26%), Positives = 49/98 (50%), Gaps = 4/98 (4%) Query: 39 KKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSEREGESEMEGGSERE---GKPE 95 + +E + K GK G+++ + K +SE E K+GK + + ++E G E + K Sbjct: 103 RTVEVDSKAAEIGKKGEDKTTQ-KDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDS 161 Query: 96 IEGKPESEGEPGSETRAAGKRPAEDDVPRKAKRKTNKG 133 +GK ++E S T + ++ +K K+ +NKG Sbjct: 162 KKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKG 199 >gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] Length = 569 Score = 47.0 bits (110), Expect = 1e-05 Identities = 31/108 (28%), Positives = 59/108 (54%), Gaps = 3/108 (2%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKD 61 E+ YSE+E + + ++ +++Q + R + E ++ E + + E K K EE ++ Sbjct: 341 EEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMK-EKEEEEMKKEEEMKKKEEKEEEEEE 399 Query: 62 KGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSE 109 + K + E E K+E EGES+ E + +G + EG+P+ +PG+E Sbjct: 400 EMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ--DPGTE 445 Score = 45.1 bits (105), Expect = 5e-05 Identities = 33/108 (30%), Positives = 59/108 (54%), Gaps = 10/108 (9%) Query: 3 KLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDK 62 +L+S+++ + E +E+ ++E K E +++K E E + E K K +EE+ + Sbjct: 356 RLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK-EEEEEEEMKQKEEEEEI---R 411 Query: 63 GKPESEGEAKEGKSEREGESEMEGGSEREGKPEIE-GKPESEGEPGSE 109 K E EGE+K+ + E E +GG + EG+P+ + G E+ GE E Sbjct: 412 NKNEEEGESKDEEDEDE-----DGGQKPEGEPQQDPGTEETYGEVEEE 454 Score = 42.0 bits (97), Expect = 4e-04 Identities = 26/90 (28%), Positives = 42/90 (46%) Query: 20 NEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEEMLKDKGKPESEGEAKEGKSERE 79 NEE+ +DE E ++ K + K ++ +K+K + E + E + K E + Sbjct: 334 NEEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEEK 393 Query: 80 GESEMEGGSEREGKPEIEGKPESEGEPGSE 109 E E E ++E + EI K E EGE E Sbjct: 394 EEEEEEEMKQKEEEEEIRNKNEEEGESKDE 423 Score = 32.0 bits (71), Expect = 0.41 Identities = 31/180 (17%), Positives = 74/180 (41%), Gaps = 15/180 (8%) Query: 2 EKLYSENEGMASNQGKMENEEQPQDERKPEVTCTLEDKKLENEGKTENKGKTGDEE---- 57 +++ + E + +M+ +E+ ++E + E+ E++++ N+ + E + K ++E Sbjct: 371 QEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDG 430 Query: 58 -------MLKDKGKPESEGEAKEGKSEREGESEMEGGSEREGKPEIEGKPESEGEPGSET 110 +D G E+ GE +E + + +++ E E P P S Sbjct: 431 GQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME--PTFVHASSQTSGPTSGY 488 Query: 111 RAAGKRPAEDDVPRKAKRKTNKGLAHYLKEYKEAIHDMNFSNEDMIREFDNMAKVQDEKR 170 A A + + ++R+ + L E + +S+ +IR + + Q +R Sbjct: 489 HAENFLGASPPIIQPSRRRNQNRVP--LLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRR 546 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.304 0.128 0.359 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,973,507 Number of Sequences: 37866 Number of extensions: 549317 Number of successful extensions: 8387 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 343 Number of HSP's successfully gapped in prelim test: 591 Number of HSP's that attempted gapping in prelim test: 3174 Number of HSP's gapped (non-prelim): 3755 length of query: 215 length of database: 18,247,518 effective HSP length: 98 effective length of query: 117 effective length of database: 14,536,650 effective search space: 1700788050 effective search space used: 1700788050 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.