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Search of human proteins with 55741864
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55741864 zinc finger, FYVE domain containing 28 [Homo
sapiens]
(887 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 1801 0.0
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 80 6e-15
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 80 6e-15
gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens] 78 3e-14
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 78 4e-14
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 77 9e-14
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 77 9e-14
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 77 9e-14
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 75 2e-13
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 74 6e-13
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens] 73 1e-12
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 71 5e-12
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 70 9e-12
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 70 9e-12
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 70 9e-12
gi|217272865 myotubularin related protein 4 [Homo sapiens] 68 3e-11
gi|153791377 apoptosis-inducing protein D [Homo sapiens] 68 3e-11
gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens] 67 6e-11
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 67 6e-11
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 67 6e-11
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 67 6e-11
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 65 2e-10
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 65 3e-10
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom... 65 3e-10
gi|13375827 phafin 2 [Homo sapiens] 65 4e-10
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 65 4e-10
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 65 4e-10
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 64 6e-10
gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens] 62 2e-09
gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens] 57 6e-08
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 1801 bits (4664), Expect = 0.0
Identities = 887/887 (100%), Positives = 887/887 (100%)
Query: 1 MMNRFRKWLYKPKRSDPQLLARFYYADEELNQVAAELDSLDGRKDPQRCTLLVSQFRSCQ 60
MMNRFRKWLYKPKRSDPQLLARFYYADEELNQVAAELDSLDGRKDPQRCTLLVSQFRSCQ
Sbjct: 1 MMNRFRKWLYKPKRSDPQLLARFYYADEELNQVAAELDSLDGRKDPQRCTLLVSQFRSCQ 60
Query: 61 DNVLNIINQIMDECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELE 120
DNVLNIINQIMDECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELE
Sbjct: 61 DNVLNIINQIMDECIPQDRAPRDFCVKFPEEIRHDNLAGQLWFGAECLAAGSIIMNRELE 120
Query: 121 SMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMV 180
SMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMV
Sbjct: 121 SMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDVLFAEFELSYVSAMV 180
Query: 181 PVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFSIPRLAIVCGLVVYA 240
PVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFSIPRLAIVCGLVVYA
Sbjct: 181 PVKSPREYYVQQEVIVLFCETVERALDFGYLTQDMIDDYEPALMFSIPRLAIVCGLVVYA 240
Query: 241 DGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQTLTEEELHTLERNLCISQDVEFPIRADV 300
DGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQTLTEEELHTLERNLCISQDVEFPIRADV
Sbjct: 241 DGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQTLTEEELHTLERNLCISQDVEFPIRADV 300
Query: 301 QGPAALAPALSAPLPPEGPLSAKAKDPDAELACSMQYDDQELEQLSRMVHRAGDEMSSLL 360
QGPAALAPALSAPLPPEGPLSAKAKDPDAELACSMQYDDQELEQLSRMVHRAGDEMSSLL
Sbjct: 301 QGPAALAPALSAPLPPEGPLSAKAKDPDAELACSMQYDDQELEQLSRMVHRAGDEMSSLL 360
Query: 361 SPPIACQSPAHRPGAEGSPGGEASPGRPRLRSGSDEEERVFFMDDVEGTAEALARPESPA 420
SPPIACQSPAHRPGAEGSPGGEASPGRPRLRSGSDEEERVFFMDDVEGTAEALARPESPA
Sbjct: 361 SPPIACQSPAHRPGAEGSPGGEASPGRPRLRSGSDEEERVFFMDDVEGTAEALARPESPA 420
Query: 421 GPFGWAGSTWADPQEKGQGGPGGAAGISLPASEKEEDLSNNNLEAEGTDGASLAGTSSCS 480
GPFGWAGSTWADPQEKGQGGPGGAAGISLPASEKEEDLSNNNLEAEGTDGASLAGTSSCS
Sbjct: 421 GPFGWAGSTWADPQEKGQGGPGGAAGISLPASEKEEDLSNNNLEAEGTDGASLAGTSSCS 480
Query: 481 CLDSRLHLDGWEVGADDAETAEMIAHRTGGMKLSATVIFNPKSPTSLDSAVATQEAASEP 540
CLDSRLHLDGWEVGADDAETAEMIAHRTGGMKLSATVIFNPKSPTSLDSAVATQEAASEP
Sbjct: 481 CLDSRLHLDGWEVGADDAETAEMIAHRTGGMKLSATVIFNPKSPTSLDSAVATQEAASEP 540
Query: 541 VAEGMDGGPHKLSTGATNCLLHSCVCCGSCGDSREDVVERLREKCSPGGVIGASYAAGLA 600
VAEGMDGGPHKLSTGATNCLLHSCVCCGSCGDSREDVVERLREKCSPGGVIGASYAAGLA
Sbjct: 541 VAEGMDGGPHKLSTGATNCLLHSCVCCGSCGDSREDVVERLREKCSPGGVIGASYAAGLA 600
Query: 601 KASDRAPERQEEAPPPSEDASNGREPKAPTSDKCLPHTSGSQVDTASGLQGEAGVAGQQE 660
KASDRAPERQEEAPPPSEDASNGREPKAPTSDKCLPHTSGSQVDTASGLQGEAGVAGQQE
Sbjct: 601 KASDRAPERQEEAPPPSEDASNGREPKAPTSDKCLPHTSGSQVDTASGLQGEAGVAGQQE 660
Query: 661 PEARELHAGSPPAHEAPQALSGSSSSTAGSCSSDKMGPEAAPAATHAAPQATREKIRSRF 720
PEARELHAGSPPAHEAPQALSGSSSSTAGSCSSDKMGPEAAPAATHAAPQATREKIRSRF
Sbjct: 661 PEARELHAGSPPAHEAPQALSGSSSSTAGSCSSDKMGPEAAPAATHAAPQATREKIRSRF 720
Query: 721 HGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLR 780
HGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLR
Sbjct: 721 HGSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLR 780
Query: 781 SAALEDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCR 840
SAALEDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCR
Sbjct: 781 SAALEDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCR 840
Query: 841 SCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKAGL 887
SCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKAGL
Sbjct: 841 SCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKAGL 887
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 80.5 bits (197), Expect = 6e-15
Identities = 117/494 (23%), Positives = 184/494 (37%), Gaps = 65/494 (13%)
Query: 431 ADPQEKGQGGPGGAAGISLPASEKEEDLSNNNLEAEGTDGASLAGTSSCSCLDS---RLH 487
A +E G P AGI + E +ED T AS G L R H
Sbjct: 696 ATKEESGVEEPAHRAGIEI--QEGKEDPLLEKESRRKTPEASAIGLHQDPELGDAALRSH 753
Query: 488 LD-GWEVGADDAETAEMIAHRTGGMK-LSATVIFNPKSPTSLDSAVATQEAASEPVAEGM 545
LD W + ++ I+ + G+ L +++ P+ SL+ V ++ E +AEG
Sbjct: 754 LDMSWPL------FSQGISEQQSGLSVLLSSLQVPPRGEDSLE--VPVEQFRIEEIAEGR 805
Query: 546 DGGPHKL--------STGATNCLLHSCVCCGSCG---DSREDVVERLREKCSPGGVIGAS 594
+ + T + LL S V + G DS D++ + K S G G
Sbjct: 806 EEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGPNVDSSTDMLVEDKVK-SVSGPQGHH 864
Query: 595 YAAGLAKASDRAPERQEEAPPPSEDA--------------SNGREPKAPTSDKCLPHTSG 640
+ + DR P+ E P PSE + S G S LP
Sbjct: 865 RSCLVNSGKDRLPQTME--PSPSETSLVERPQVGSVVHRTSLGSTLSLTRSPCALPLAEC 922
Query: 641 SQVDTASGLQGEAGVAGQQEPEARELHAGSPPAHEAPQALSGSSSST------AGSCSSD 694
+ +G A +Q P L P +G S + A SCSS
Sbjct: 923 KEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSCSSA 982
Query: 695 KM-----------GPEAAPAATHAAPQATREKIRSRFHGSHD--LIHRLFVCISGVADQL 741
+ P+AT + Q +R + + + RL SG ++
Sbjct: 983 HLHSRNLHHKWLHSHSGRPSATSSPDQPSRSHLDDDGMSVYTDTIQQRLRQIESGHQQEV 1042
Query: 742 QT--NYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSEL 799
+T +L+S L++ + + D +++ + + S ++C T SE
Sbjct: 1043 ETLKKQVQELKSRLESQYLTSSLHFNGDFGDEVTSIPDS-ESNLDQNCLSRCSTEIFSEA 1101
Query: 800 AAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPR 859
+ + D + W+PD C AC + F + RKHHCR+CG +FCS C + P+P
Sbjct: 1102 SWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPS 1161
Query: 860 YGQVKPVRVCTHCY 873
+P RVC CY
Sbjct: 1162 QQLFEPSRVCKSCY 1175
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 80.5 bits (197), Expect = 6e-15
Identities = 33/63 (52%), Positives = 37/63 (58%)
Query: 810 DPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVC 869
+ P+WVPD+ C C C A F + RKHHCR CGK FC RC S PL R V PVR C
Sbjct: 37 EEPQWVPDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQC 96
Query: 870 THC 872
C
Sbjct: 97 AEC 99
>gi|189217917 FYVE, RhoGEF and PH domain containing 2 [Homo sapiens]
Length = 655
Score = 78.2 bits (191), Expect = 3e-14
Identities = 39/108 (36%), Positives = 61/108 (56%), Gaps = 11/108 (10%)
Query: 770 EKLRKVTQTLRSAAL-EDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKA 828
+++ K +T ++AA + + ++ L S EL + P+WV D+ C C+
Sbjct: 418 DQIEKRNETFKAAAQGPEGDIQEQELQSEELGLRA--------PQWVRDKMVTMCMRCQE 469
Query: 829 PFTVI-RRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMF 875
PF + RR+HHCR+CG + C+RCS + A L +Y +P RVC HCY F
Sbjct: 470 PFNALTRRRHHCRACGYVVCARCSDYRAEL-KYDDNRPNRVCLHCYAF 516
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 77.8 bits (190), Expect = 4e-14
Identities = 119/493 (24%), Positives = 175/493 (35%), Gaps = 100/493 (20%)
Query: 431 ADPQEKGQGGPGGAAGISLPASEKEEDLSNNNLEAEGTDGASLAGTSSCSCLDS---RLH 487
A +E G P AGI + E +ED T AS G L R H
Sbjct: 696 ATKEESGVEEPAHRAGIEI--QEGKEDPLLEKESRRKTPEASAIGLHQDPELGDAALRSH 753
Query: 488 LD-GWEVGADDAETAEMIAHRTGGMK-LSATVIFNPKSPTSLDSAVATQEAASEPVAEGM 545
LD W + ++ I+ + G+ L +++ P+ SL+ V ++ E +AEG
Sbjct: 754 LDMSWPL------FSQGISEQQSGLSVLLSSLQVPPRGEDSLE--VPVEQFRIEEIAEGR 805
Query: 546 DGGPHKL--------STGATNCLLHSCVCCGSCG---DSREDVVERLREKCSPGGVIGAS 594
+ + T + LL S V + G DS D++ + K S G G
Sbjct: 806 EEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGPNVDSSTDMLVEDKVK-SVSGPQGHH 864
Query: 595 YAAGLAKASDRAPERQEEAPPPSEDA--------------SNGREPKAPTSDKCLPHTSG 640
+ + DR P+ E P PSE + S G S LP
Sbjct: 865 RSCLVNSGKDRLPQTME--PSPSETSLVERPQVGSVVHRTSLGSTLSLTRSPCALPLAEC 922
Query: 641 SQVDTASGLQGEAGVAGQQEPEARELHAGSPPAHEAPQALSGSSSST------AGSCSSD 694
+ +G A +Q P L P +G S + A SCSS
Sbjct: 923 KEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSCSSA 982
Query: 695 KM-----------GPEAAPAATHAAPQATREKIRSRFHGSHDLIHRLFVCISGVADQLQT 743
+ P+AT + Q +R S + D +
Sbjct: 983 HLHSRNLHHKWLHSHSGRPSATSSPDQPSR---------------------SHLDDDGMS 1021
Query: 744 NYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSELAAKT 803
Y ++ L+ + + E L+K Q L+S L S L +
Sbjct: 1022 VYTDTIQQRLRQI-----ESGHQQEVETLKKQVQELKSR-----------LESQYLTSSL 1065
Query: 804 R-DGDFEDP--PEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRY 860
+GDF D W+PD C AC + F + RKHHCR+CG +FCS C + P+P
Sbjct: 1066 HFNGDFGDEVMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVPVPSQ 1125
Query: 861 GQVKPVRVCTHCY 873
+P RVC CY
Sbjct: 1126 QLFEPSRVCKSCY 1138
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 76.6 bits (187), Expect = 9e-14
Identities = 50/145 (34%), Positives = 77/145 (53%), Gaps = 21/145 (14%)
Query: 740 QLQTNYASDLRSILKT-LFEVMATKPET----DDKEKLRKVTQTLRSAALEDCALCQETL 794
Q + + D S+L+ L +V K E D+K +L+K+ + + AL++ L L
Sbjct: 454 QRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEE-QEQALQEMGL---HL 509
Query: 795 SSSELAAKTRDGDFEDPPE------WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCS 848
S S+L + D ++ + W+ D+ C C+ F++ RRKHHCR+CG IFC+
Sbjct: 510 SQSKLKME----DIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCN 565
Query: 849 RCSSHSAPLPRYGQVKPVRVCTHCY 873
CSS+ LP Y KPVRVC C+
Sbjct: 566 TCSSNELALPSY--PKPVRVCDSCH 588
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 76.6 bits (187), Expect = 9e-14
Identities = 50/145 (34%), Positives = 77/145 (53%), Gaps = 21/145 (14%)
Query: 740 QLQTNYASDLRSILKT-LFEVMATKPET----DDKEKLRKVTQTLRSAALEDCALCQETL 794
Q + + D S+L+ L +V K E D+K +L+K+ + + AL++ L L
Sbjct: 454 QRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEE-QEQALQEMGL---HL 509
Query: 795 SSSELAAKTRDGDFEDPPE------WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCS 848
S S+L + D ++ + W+ D+ C C+ F++ RRKHHCR+CG IFC+
Sbjct: 510 SQSKLKME----DIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCN 565
Query: 849 RCSSHSAPLPRYGQVKPVRVCTHCY 873
CSS+ LP Y KPVRVC C+
Sbjct: 566 TCSSNELALPSY--PKPVRVCDSCH 588
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 76.6 bits (187), Expect = 9e-14
Identities = 50/145 (34%), Positives = 77/145 (53%), Gaps = 21/145 (14%)
Query: 740 QLQTNYASDLRSILKT-LFEVMATKPET----DDKEKLRKVTQTLRSAALEDCALCQETL 794
Q + + D S+L+ L +V K E D+K +L+K+ + + AL++ L L
Sbjct: 562 QRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEE-QEQALQEMGL---HL 617
Query: 795 SSSELAAKTRDGDFEDPPE------WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCS 848
S S+L + D ++ + W+ D+ C C+ F++ RRKHHCR+CG IFC+
Sbjct: 618 SQSKLKME----DIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCN 673
Query: 849 RCSSHSAPLPRYGQVKPVRVCTHCY 873
CSS+ LP Y KPVRVC C+
Sbjct: 674 TCSSNELALPSY--PKPVRVCDSCH 696
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 75.5 bits (184), Expect = 2e-13
Identities = 42/120 (35%), Positives = 61/120 (50%), Gaps = 10/120 (8%)
Query: 754 KTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSELAAKTRDGDFEDPPE 813
K L+ + A ++ K + V T + +E + S + AA E P+
Sbjct: 107 KILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAA-------ERAPD 159
Query: 814 WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
WV E C C+ F V+ RKHHCR+CG+IFC +CSS + +P++G K VRVC CY
Sbjct: 160 WVDAEECH---RCRVQFGVMTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCY 216
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 73.9 bits (180), Expect = 6e-13
Identities = 31/74 (41%), Positives = 41/74 (55%), Gaps = 2/74 (2%)
Query: 799 LAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLP 858
+ K++D D + W+PD C C C FT RR+HHCR CG+IFCSRC + P
Sbjct: 142 MEGKSQDSDLKQ--YWMPDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGK 199
Query: 859 RYGQVKPVRVCTHC 872
G +R CT+C
Sbjct: 200 FMGYTGDLRACTYC 213
>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
Length = 1430
Score = 72.8 bits (177), Expect = 1e-12
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
Query: 722 GSHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLRS 781
G + L + L + V Q Y ++L+ +++ T+ E L +++ +
Sbjct: 1125 GMYKLNNMLSLAGMKVRKPTQEAYQNELKIESVERSFILSASSATERDEWLEAISRAIEE 1184
Query: 782 AALEDCALC-QETLSSSELAAKTRDGDF-EDPPEWVPDEACGFCTACKAPFTVIRRKHHC 839
A + C +L ++ K P W+PD C C + FT+ R+HHC
Sbjct: 1185 YAKKRITFCPSRSLDEADSENKEEVSPLGSKAPIWIPDTRATMCMICTSEFTLTWRRHHC 1244
Query: 840 RSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
R+CGKI C CSS+ L Y + +P RVC HC+
Sbjct: 1245 RACGKIVCQACSSNKYGLD-YLKNQPARVCEHCF 1277
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 70.9 bits (172), Expect = 5e-12
Identities = 28/60 (46%), Positives = 39/60 (65%), Gaps = 2/60 (3%)
Query: 814 WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
W+ D+ C C+ F++ +RKHHCR+CG+IFC+ CS + PLP KPVRVC C+
Sbjct: 572 WLKDKEATHCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLP--SSPKPVRVCDSCH 629
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 70.1 bits (170), Expect = 9e-12
Identities = 119/502 (23%), Positives = 175/502 (34%), Gaps = 109/502 (21%)
Query: 431 ADPQEKGQGGPGGAAGISLPASEKEEDLSNNNLEAEGTDGASLAGTSSCSCLDS---RLH 487
A +E G P AGI + E +ED T AS G L R H
Sbjct: 696 ATKEESGVEEPAHRAGIEI--QEGKEDPLLEKESRRKTPEASAIGLHQDPELGDAALRSH 753
Query: 488 LD-GWEVGADDAETAEMIAHRTGGMK-LSATVIFNPKSPTSLDSAVATQEAASEPVAEGM 545
LD W + ++ I+ + G+ L +++ P+ SL+ V ++ E +AEG
Sbjct: 754 LDMSWPL------FSQGISEQQSGLSVLLSSLQVPPRGEDSLE--VPVEQFRIEEIAEGR 805
Query: 546 DGGPHKL--------STGATNCLLHSCVCCGSCG---DSREDVVERLREKCSPGGVIGAS 594
+ + T + LL S V + G DS D++ + K S G G
Sbjct: 806 EEAVLPIPVDAKVGYGTSQSCSLLPSQVPFETRGPNVDSSTDMLVEDKVK-SVSGPQGHH 864
Query: 595 YAAGLAKASDRAPERQEEAPPPSEDA--------------SNGREPKAPTSDKCLPHTSG 640
+ + DR P+ E P PSE + S G S LP
Sbjct: 865 RSCLVNSGKDRLPQTME--PSPSETSLVERPQVGSVVHRTSLGSTLSLTRSPCALPLAEC 922
Query: 641 SQVDTASGLQGEAGVAGQQEPEARELHAGSPPAHEAPQALSGSSSST------AGSCSSD 694
+ +G A +Q P L P +G S + A SCSS
Sbjct: 923 KEGLVCNGAPETENRASEQPPGLSTLQMYPTPNGHCANGEAGRSKDSLSRQLSAMSCSSA 982
Query: 695 KM-----------GPEAAPAATHAAPQATREKIRSRFHGSHDLIHRLFVCISGVADQLQT 743
+ P+AT + Q +R S + D +
Sbjct: 983 HLHSRNLHHKWLHSHSGRPSATSSPDQPSR---------------------SHLDDDGMS 1021
Query: 744 NYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSELAAKT 803
Y ++ L+ + + E L+K Q L+S L S L +
Sbjct: 1022 VYTDTIQQRLRQI-----ESGHQQEVETLKKQVQELKSR-----------LESQYLTSSL 1065
Query: 804 R-DGDFEDP--PEWVPDEACGFCTACKAPFTVIRRKHHCR---------SCGKIFCSRCS 851
+GDF D W+PD C AC + F + RKHHCR +CG +FCS C
Sbjct: 1066 HFNGDFGDEVMTRWLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGNVFCSSCC 1125
Query: 852 SHSAPLPRYGQVKPVRVCTHCY 873
+ P+P +P RVC CY
Sbjct: 1126 NQKVPVPSQQLFEPSRVCKSCY 1147
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 70.1 bits (170), Expect = 9e-12
Identities = 26/60 (43%), Positives = 37/60 (61%)
Query: 814 WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
WV DE C+ C F++ R+HHCR+CG++FC +CS + + R PVRVC +CY
Sbjct: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 70.1 bits (170), Expect = 9e-12
Identities = 26/60 (43%), Positives = 37/60 (61%)
Query: 814 WVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
WV DE C+ C F++ R+HHCR+CG++FC +CS + + R PVRVC +CY
Sbjct: 3451 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 3510
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 68.2 bits (165), Expect = 3e-11
Identities = 35/105 (33%), Positives = 46/105 (43%), Gaps = 8/105 (7%)
Query: 769 KEKLRKVTQTLRSAALEDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKA 828
KE T+ S EDC SE + + D + WVPD C C
Sbjct: 1074 KESDGSDTEDFGSDHSEDCL--------SEASWEPVDKKETEVTRWVPDHMASHCYNCDC 1125
Query: 829 PFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
F + +R+HHCR+CG +FC+ C P+P PV VC CY
Sbjct: 1126 EFWLAKRRHHCRNCGNVFCAGCCHLKLPIPDQQLYDPVLVCNSCY 1170
>gi|153791377 apoptosis-inducing protein D [Homo sapiens]
Length = 279
Score = 68.2 bits (165), Expect = 3e-11
Identities = 32/77 (41%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 798 ELAAKTRDGDFEDPPEWVPDEACGFCTAC-KAPFTVIRRKHHCRSCGKIFCSRCSSHSAP 856
+L A R E W+PD+A C C + F+ + R+HHCR CG + C+ CS
Sbjct: 133 QLRATGRPPSTEHAAPWIPDKATDICMRCTQTRFSALTRRHHCRKCGFVVCAECSRQRFL 192
Query: 857 LPRYGQVKPVRVCTHCY 873
LPR KPVRVC+ CY
Sbjct: 193 LPRLSP-KPVRVCSLCY 208
>gi|198041928 FYVE, RhoGEF and PH domain containing 4 [Homo sapiens]
Length = 766
Score = 67.4 bits (163), Expect = 6e-11
Identities = 42/135 (31%), Positives = 64/135 (47%), Gaps = 20/135 (14%)
Query: 740 QLQTNYASDLRSILKTLFEVMATKPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSEL 799
+LQ + A D +K L E + + + +T R+A +D + E +S++EL
Sbjct: 500 ELQASSAQDKEEWIKALQETI---------DAFHQRHETFRNAIAKDNDIHSE-VSTAEL 549
Query: 800 AAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVI-RRKHHCRSCGKIFCSRCSSHSAPLP 858
+ P W+ D C CK PF + RR+HHCR+CG + C +CS + A L
Sbjct: 550 GKRA--------PRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQL- 600
Query: 859 RYGQVKPVRVCTHCY 873
Y K +VC CY
Sbjct: 601 EYDGGKLSKVCKDCY 615
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 67.4 bits (163), Expect = 6e-11
Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 809 EDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRV 868
E P WVPD C C+A FT +R+HHCR+CGK+FC+ C S L Y K RV
Sbjct: 691 EVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKL-LYMDRKEARV 749
Query: 869 CTHCY 873
C C+
Sbjct: 750 CVICH 754
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 67.4 bits (163), Expect = 6e-11
Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 809 EDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRV 868
E P WVPD C C+A FT +R+HHCR+CGK+FC+ C S L Y K RV
Sbjct: 691 EVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKL-LYMDRKEARV 749
Query: 869 CTHCY 873
C C+
Sbjct: 750 CVICH 754
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 67.4 bits (163), Expect = 6e-11
Identities = 30/65 (46%), Positives = 37/65 (56%), Gaps = 1/65 (1%)
Query: 809 EDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRV 868
E P WVPD C C+A FT +R+HHCR+CGK+FC+ C S L Y K RV
Sbjct: 691 EVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKL-LYMDRKEARV 749
Query: 869 CTHCY 873
C C+
Sbjct: 750 CVICH 754
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 65.5 bits (158), Expect = 2e-10
Identities = 39/111 (35%), Positives = 54/111 (48%), Gaps = 12/111 (10%)
Query: 763 KPETDDKEKLRKVTQTLRSAALEDCALCQETLSSSELAAKTRDGDFEDPPEWVPDEACGF 822
K +T E RK+ T +AA+++ ++L A R +W D
Sbjct: 1308 KLQTKVLELQRKLDNT--TAAVQELGRENQSLQIKHTQALNR--------KWAEDNEVQN 1357
Query: 823 CTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
C AC F+V R+HHCR CG IFC+ CS+ +A P KPVRVC C+
Sbjct: 1358 CMACGKGFSVTVRRHHCRQCGNIFCAECSAKNALTP--SSKKPVRVCDACF 1406
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 65.1 bits (157), Expect = 3e-10
Identities = 28/66 (42%), Positives = 35/66 (53%)
Query: 807 DFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPV 866
D P WVPD C C+ F++ KHHCR+CG+ FC CS +P G PV
Sbjct: 290 DAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPV 349
Query: 867 RVCTHC 872
RVC +C
Sbjct: 350 RVCFNC 355
Score = 61.6 bits (148), Expect = 3e-09
Identities = 28/64 (43%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Query: 811 PPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYG-QVKPVRVC 869
P W P+ C C F KHHCR+CG+ FC CSS + P+P G PVRVC
Sbjct: 177 PAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVC 236
Query: 870 THCY 873
+CY
Sbjct: 237 DNCY 240
>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
sapiens]
Length = 777
Score = 65.1 bits (157), Expect = 3e-10
Identities = 28/66 (42%), Positives = 35/66 (53%)
Query: 807 DFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPV 866
D P WVPD C C+ F++ KHHCR+CG+ FC CS +P G PV
Sbjct: 705 DAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRACGQGFCDECSHDRRAVPSRGWDHPV 764
Query: 867 RVCTHC 872
RVC +C
Sbjct: 765 RVCFNC 770
Score = 61.6 bits (148), Expect = 3e-09
Identities = 28/64 (43%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Query: 811 PPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYG-QVKPVRVC 869
P W P+ C C F KHHCR+CG+ FC CSS + P+P G PVRVC
Sbjct: 592 PAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVPERGWGPAPVRVC 651
Query: 870 THCY 873
+CY
Sbjct: 652 DNCY 655
>gi|13375827 phafin 2 [Homo sapiens]
Length = 249
Score = 64.7 bits (156), Expect = 4e-10
Identities = 29/61 (47%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Query: 814 WVPDEACGFCTAC-KAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHC 872
WVPD C C KA FT + R+HHCR CG + C CS LP KPVR+C C
Sbjct: 149 WVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSS-KPVRICDFC 207
Query: 873 Y 873
Y
Sbjct: 208 Y 208
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 64.7 bits (156), Expect = 4e-10
Identities = 28/62 (45%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 812 PEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTH 871
P WVPD C C+ FT +R+HHCR+CGK+FC C + L +Y + K RVC
Sbjct: 742 PTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL-QYLE-KEARVCVV 799
Query: 872 CY 873
CY
Sbjct: 800 CY 801
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 64.7 bits (156), Expect = 4e-10
Identities = 28/62 (45%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Query: 812 PEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTH 871
P WVPD C C+ FT +R+HHCR+CGK+FC C + L +Y + K RVC
Sbjct: 742 PTWVPDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKL-QYLE-KEARVCVV 799
Query: 872 CY 873
CY
Sbjct: 800 CY 801
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 63.9 bits (154), Expect = 6e-10
Identities = 29/80 (36%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Query: 794 LSSSELAAKTRDGDFEDPPEWVPDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSH 853
+++ +L + D ++PP W +C C A F V RKHHCR CG++ C +CS+
Sbjct: 1086 VATKQLLFRLLDMLSKEPP-WCDGS---YCYECTARFGVTTRKHHCRHCGRLLCHKCSTK 1141
Query: 854 SAPLPRYGQVKPVRVCTHCY 873
P+ ++ KPVRVC C+
Sbjct: 1142 EIPIIKFDLNKPVRVCNICF 1161
>gi|38202205 zinc finger, FYVE domain containing 26 [Homo sapiens]
Length = 2539
Score = 62.4 bits (150), Expect = 2e-09
Identities = 26/64 (40%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query: 813 EWVPDEACGFC-TACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTH 871
+WVPDE C C+ FT+ R+HHCR CG++ CS CS+ + + P RVC
Sbjct: 1808 QWVPDETESICMVCCREHFTMFNRRHHCRRCGRLVCSSCSTKKMVVEGCRE-NPARVCDQ 1866
Query: 872 CYMF 875
CY +
Sbjct: 1867 CYSY 1870
>gi|18482373 WD repeat and FYVE domain containing 1 [Homo sapiens]
Length = 410
Score = 57.4 bits (137), Expect = 6e-08
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 14/90 (15%)
Query: 795 SSSELAAKTRDGDFEDPPEWVPDEACGFCTACKAPF-----------TVIRRKHHCRSCG 843
S +A D E+ P+W+ ++C C+ PF T+ R+HHCR CG
Sbjct: 262 SDGGIAVWNMDVSREEAPQWLESDSC---QKCEQPFFWNIKQMWDTKTLGLRQHHCRKCG 318
Query: 844 KIFCSRCSSHSAPLPRYGQVKPVRVCTHCY 873
+ C +CSS + P G VRVC CY
Sbjct: 319 QAVCGKCSSKRSSYPVMGFEFQVRVCDSCY 348
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,165,379
Number of Sequences: 37866
Number of extensions: 2038421
Number of successful extensions: 15153
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 396
Number of HSP's that attempted gapping in prelim test: 12029
Number of HSP's gapped (non-prelim): 3060
length of query: 887
length of database: 18,247,518
effective HSP length: 111
effective length of query: 776
effective length of database: 14,044,392
effective search space: 10898448192
effective search space used: 10898448192
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.