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Search of human proteins with 55741845
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo
sapiens]
(1063 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens] 2188 0.0
gi|5454158 valyl-tRNA synthetase [Homo sapiens] 1008 0.0
gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] 184 4e-46
gi|94721239 isoleucine tRNA synthetase [Homo sapiens] 122 1e-27
gi|94721241 isoleucine tRNA synthetase [Homo sapiens] 122 1e-27
gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho... 67 7e-11
gi|74271888 lipin 3 [Homo sapiens] 36 0.22
gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens] 36 0.22
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su... 33 1.1
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su... 33 1.1
gi|108773810 leucyl-tRNA synthetase [Homo sapiens] 33 1.4
gi|13376259 nucleoporin 85 [Homo sapiens] 33 1.4
gi|18959210 WIRE protein [Homo sapiens] 33 1.4
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor... 33 1.9
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor... 33 1.9
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor... 33 1.9
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor... 33 1.9
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] 32 2.4
gi|4885185 distal-less homeobox 3 [Homo sapiens] 32 3.2
gi|169214926 PREDICTED: similar to IQ motif and SEC7 domain-cont... 32 3.2
gi|113428915 PREDICTED: similar to IQ motif and SEC7 domain-cont... 32 3.2
gi|21359974 vitrin [Homo sapiens] 32 3.2
gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens] 31 5.4
gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens] 31 5.4
gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform ... 31 7.1
gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform ... 31 7.1
gi|24497609 nucleoporin 62kDa [Homo sapiens] 31 7.1
gi|24497607 nucleoporin 62kDa [Homo sapiens] 31 7.1
gi|24497605 nucleoporin 62kDa [Homo sapiens] 31 7.1
gi|24497603 nucleoporin 62kDa [Homo sapiens] 31 7.1
>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
Length = 1063
Score = 2188 bits (5670), Expect = 0.0
Identities = 1063/1063 (100%), Positives = 1063/1063 (100%)
Query: 1 MPHLPLASFRPPFWGLRHSRGLPRFHSVSTQSEPHGSPISRRNREAKQKRLREKQATLEA 60
MPHLPLASFRPPFWGLRHSRGLPRFHSVSTQSEPHGSPISRRNREAKQKRLREKQATLEA
Sbjct: 1 MPHLPLASFRPPFWGLRHSRGLPRFHSVSTQSEPHGSPISRRNREAKQKRLREKQATLEA 60
Query: 61 EIAGESKSPAESIKAWRPKELVLYEIPTKPGEKKDVSGPLPPAYSPRYVEAAWYPWWVRE 120
EIAGESKSPAESIKAWRPKELVLYEIPTKPGEKKDVSGPLPPAYSPRYVEAAWYPWWVRE
Sbjct: 61 EIAGESKSPAESIKAWRPKELVLYEIPTKPGEKKDVSGPLPPAYSPRYVEAAWYPWWVRE 120
Query: 121 GFFKPEYQARLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWV 180
GFFKPEYQARLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWV
Sbjct: 121 GFFKPEYQARLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWV 180
Query: 181 PGSDHAGIATQAVVEKQLWKERGVRRHELSREAFLREVWQWKEAKGGEICEQLRALGASL 240
PGSDHAGIATQAVVEKQLWKERGVRRHELSREAFLREVWQWKEAKGGEICEQLRALGASL
Sbjct: 181 PGSDHAGIATQAVVEKQLWKERGVRRHELSREAFLREVWQWKEAKGGEICEQLRALGASL 240
Query: 241 DWDRECFTMDVGSSVAVTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGH 300
DWDRECFTMDVGSSVAVTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGH
Sbjct: 241 DWDRECFTMDVGSSVAVTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGH 300
Query: 301 TQLRLPGCPTPVSFGLLFSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDSRYTHL 360
TQLRLPGCPTPVSFGLLFSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDSRYTHL
Sbjct: 301 TQLRLPGCPTPVSFGLLFSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDSRYTHL 360
Query: 361 HGRQLRHPLMGQPLPLITDYAVQPHVGTGAVKVTPAHSPADAEMGARHGLSPLNVIAEDG 420
HGRQLRHPLMGQPLPLITDYAVQPHVGTGAVKVTPAHSPADAEMGARHGLSPLNVIAEDG
Sbjct: 361 HGRQLRHPLMGQPLPLITDYAVQPHVGTGAVKVTPAHSPADAEMGARHGLSPLNVIAEDG 420
Query: 421 TMTSLCGDWLQGLHRFVAREKIMSVLSEWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQW 480
TMTSLCGDWLQGLHRFVAREKIMSVLSEWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQW
Sbjct: 421 TMTSLCGDWLQGLHRFVAREKIMSVLSEWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQW 480
Query: 481 FVRCQEMGARAAKAVESGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHQIPAYLVVE 540
FVRCQEMGARAAKAVESGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHQIPAYLVVE
Sbjct: 481 FVRCQEMGARAAKAVESGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHQIPAYLVVE 540
Query: 541 DHAQGEEDCWVVGRSEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWP 600
DHAQGEEDCWVVGRSEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWP
Sbjct: 541 DHAQGEEDCWVVGRSEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWP 600
Query: 601 QETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMS 660
QETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMS
Sbjct: 601 QETPDLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMS 660
Query: 661 KSLGNVLDPRDIISGVEMQVLQEKLRSGNLDPAELAIVAAAQKKDFPHGIPECGTDALRF 720
KSLGNVLDPRDIISGVEMQVLQEKLRSGNLDPAELAIVAAAQKKDFPHGIPECGTDALRF
Sbjct: 661 KSLGNVLDPRDIISGVEMQVLQEKLRSGNLDPAELAIVAAAQKKDFPHGIPECGTDALRF 720
Query: 721 TLCSHGVQAGDLHLSVSEVQSCRHFCNKIWNALRFILNALGEKFVPQPAEELSPSSPMDA 780
TLCSHGVQAGDLHLSVSEVQSCRHFCNKIWNALRFILNALGEKFVPQPAEELSPSSPMDA
Sbjct: 721 TLCSHGVQAGDLHLSVSEVQSCRHFCNKIWNALRFILNALGEKFVPQPAEELSPSSPMDA 780
Query: 781 WILSRLALAAQECERGFLTRELSLVTHALHHFWLHNLCDVYLEAVKPVLWHSPRPLGPPQ 840
WILSRLALAAQECERGFLTRELSLVTHALHHFWLHNLCDVYLEAVKPVLWHSPRPLGPPQ
Sbjct: 781 WILSRLALAAQECERGFLTRELSLVTHALHHFWLHNLCDVYLEAVKPVLWHSPRPLGPPQ 840
Query: 841 VLFSCADLGLRLLAPLMPFLAEELWQRLPPRPGCPPAPSISVAPYPSACSLEHWRQPELE 900
VLFSCADLGLRLLAPLMPFLAEELWQRLPPRPGCPPAPSISVAPYPSACSLEHWRQPELE
Sbjct: 841 VLFSCADLGLRLLAPLMPFLAEELWQRLPPRPGCPPAPSISVAPYPSACSLEHWRQPELE 900
Query: 901 RRFSRVQEVVQVLRALRATYQLTKARPRVLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGL 960
RRFSRVQEVVQVLRALRATYQLTKARPRVLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGL
Sbjct: 901 RRFSRVQEVVQVLRALRATYQLTKARPRVLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGL 960
Query: 961 LPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYKLQKQLDSLTARTPSE 1020
LPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYKLQKQLDSLTARTPSE
Sbjct: 961 LPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYKLQKQLDSLTARTPSE 1020
Query: 1021 GEAGTQRQQKLSSLQLELSKLDKAASHLQQLMDEPPAPGSPEL 1063
GEAGTQRQQKLSSLQLELSKLDKAASHLQQLMDEPPAPGSPEL
Sbjct: 1021 GEAGTQRQQKLSSLQLELSKLDKAASHLQQLMDEPPAPGSPEL 1063
>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
Length = 1264
Score = 1008 bits (2607), Expect = 0.0
Identities = 524/1059 (49%), Positives = 688/1059 (64%), Gaps = 28/1059 (2%)
Query: 18 HSRGLPRFHSVSTQSEPHGSPISRRNREAKQK----RLREKQATLEAEIAGESKSPAESI 73
+S P H ++ ++ +EAK++ + ++KQ + + K P
Sbjct: 210 YSGARPLSHQPGPEAPALPKTAAQLKKEAKKREKLEKFQQKQKIQQQQPPPGEKKPKPEK 269
Query: 74 KAWRPKELVLYEIPTKPGEKKDVSGPLPPAYSPRYVEAAWYPWWVREGFFKPEYQARLPQ 133
+ R ++ Y++PT PGEKKDVSGP+P +YSPRYVEAAWYPWW ++GFFKPEY
Sbjct: 270 REKRDPGVITYDLPTPPGEKKDVSGPMPDSYSPRYVEAAWYPWWEQQGFFKPEYGRPNVS 329
Query: 134 ATGE--TFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQ 191
A F MCIPPPNVTGSLH+GHALT AIQD+L RWHRMRG+ LW PG DHAGIATQ
Sbjct: 330 AANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRGETTLWNPGCDHAGIATQ 389
Query: 192 AVVEKQLWKERGVRRHELSREAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDV 251
VVEK+LW+E+G+ RH+L REAFL+EVW+WKE KG I QL+ LG+SLDWDR CFTMD
Sbjct: 390 VVVEKKLWREQGLSRHQLGREAFLQEVWKWKEEKGDRIYHQLKKLGSSLDWDRACFTMDP 449
Query: 252 GSSVAVTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGHTQLRLPGCPTP 311
S AVTEAFVRL++ G++YR+ +LVNWSC L SAISDIEV+ + L G T L +PG
Sbjct: 450 KLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGRTLLSVPGYKEK 509
Query: 312 VSFGLLFSVAFPVDG-EPDAEVVVGTTRPETLPGDVAVAVHPDDSRYTHLHGRQLRHPLM 370
V FG+L S A+ V G + D EVVV TTR ET+ GDVAVAVHP D+RY HL G+ + HP +
Sbjct: 510 VEFGVLVSFAYKVQGSDSDEEVVVATTRIETMLGDVAVAVHPKDTRYQHLKGKNVIHPFL 569
Query: 371 GQPLPLITDYAVQPHVGTGAVKVTPAHSPADAEMGARHGLSPLNVIAEDGTMTSLCGDWL 430
+ LP++ D V GTGAVK+TPAH D E+G RHGL ++++ G + ++ +L
Sbjct: 570 SRSLPIVFDEFVDMDFGTGAVKITPAHDQNDYEVGQRHGLEAISIMDSRGALINVPPPFL 629
Query: 431 QGLHRFVAREKIMSVLSEWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQWFVRCQEMGAR 490
GL RF AR+ ++ L E GLFRG++++PMV+P+C+RS DV+E LL+ QW+VRC EM
Sbjct: 630 -GLPRFEARKAVLVALKERGLFRGIEDNPMVVPLCNRSKDVVEPLLRPQWYVRCGEMAQA 688
Query: 491 AAKAVESGALELSPSFHQKNWQHWFSHIGDWCVSRQLWWGHQIPAYLV-VEDHA--QGEE 547
A+ AV G L + P HQ+ W W +I +WC+SRQLWWGH+IPAY V V D A GE+
Sbjct: 689 ASAAVTRGDLRILPEAHQRTWHAWMDNIREWCISRQLWWGHRIPAYFVTVSDPAVPPGED 748
Query: 548 D---CWVVGRSEAEAREVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWPQETP 604
WV GR+EAEARE AA+ G +++L++D DVLDTWFSS LFP S LGWP ++
Sbjct: 749 PDGRYWVSGRNEAEAREKAAKEFGVSPDKISLQQDEDVLDTWFSSGLFPLSILGWPNQSE 808
Query: 605 DLARFYPLSLLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMSKSLG 664
DL+ FYP +LLETG D+L FWV RMVMLG +LTG+LPF +V LH +VRD GRKMSKSLG
Sbjct: 809 DLSVFYPGTLLETGHDILFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAHGRKMSKSLG 868
Query: 665 NVLDPRDIISGVEMQVLQEKLRSGNLDPAELAIVAAAQKKDFPHGIPECGTDALRFTLCS 724
NV+DP D+I G+ +Q L +L + NLDP+E+ QK DFP GIPECGTDALRF LC+
Sbjct: 869 NVIDPLDVIYGISLQGLHNQLLNSNLDPSEVEKAKEGQKADFPAGIPECGTDALRFGLCA 928
Query: 725 HGVQAGDLHLSVSEVQSCRHFCNKIWNALRFILNALGEKFVPQPAEEL-SPSSPMDAWIL 783
+ Q D++L V+ + RHFCNK+WNA +F L LG+ FVP P + S +D WI
Sbjct: 929 YMSQGRDINLDVNRILGYRHFCNKLWNATKFALRGLGKGFVPSPTSQPGGHESLVDRWIR 988
Query: 784 SRLALAAQECERGFLTRELSLVTHALHHFWLHNLCDVYLEAVKPVLWHSPRPLG--PPQV 841
SRL A + +GF + VT A + FWL+ LCDVYLE +KPVL + Q
Sbjct: 989 SRLTEAVRLSNQGFQAYDFPAVTTAQYSFWLYELCDVYLECLKPVLNGVDQVAAECARQT 1048
Query: 842 LFSCADLGLRLLAPLMPFLAEELWQRLPPR-PGCPPAPSISVAPYPSACSLEHWRQPELE 900
L++C D+GLRLL+P MPF+ EEL+QRLP R P PP+ ++ P PS CS W+ PE E
Sbjct: 1049 LYTCLDVGLRLLSPFMPFVTEELFQRLPRRMPQAPPSLCVTPYPEPSECS---WKDPEAE 1105
Query: 901 RRFSRVQEVVQVLRALRATYQLTKARPRVLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGL 960
+ + +R+LRA Y LT+ RP L+ ++ L A + L G V +
Sbjct: 1106 AALELALSITRAVRSLRADYNLTRIRPDCFLEVADEATGALASAVSGYVQALASAGVVAV 1165
Query: 961 LPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYKLQKQLDSLTARTPSE 1020
L GA AP G A A SD ++++LQGLVDP +L L A+R + Q+Q L R +
Sbjct: 1166 LALGAPAPQGCAVALASDRCSIHLQLQGLVDPARELGKLQAKRVEAQRQAQRLRERRAAS 1225
Query: 1021 G-------EAGTQRQQKLSSLQLELSKLDKAASHLQQLM 1052
G E + KL + EL K+D+A + Q+++
Sbjct: 1226 GYPVKVPLEVQEADEAKLQQTEAELRKVDEAIALFQKML 1264
>gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]
Length = 1012
Score = 184 bits (467), Expect = 4e-46
Identities = 196/824 (23%), Positives = 324/824 (39%), Gaps = 130/824 (15%)
Query: 145 PPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQAVVEKQLWKERGV 204
PP G H+GHAL ++D R+H M G ++ +VPG D G+ +E ++ E G
Sbjct: 115 PPYANGDPHVGHALNKILKDIANRFHMMNGSKIHFVPGWDCHGLP----IEIKVLSELGR 170
Query: 205 RRHELSREAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVAVTEAFVRL 264
LS ++ + +A + G DW+ +T D F ++
Sbjct: 171 EAQNLSAMEIRKKARSFAKAAIEKQKSAFIRWGIMADWNNCYYTFDGKYEAKQLRTFYQM 230
Query: 265 YKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGHTQLRLPGCPTPVSFGLLF---SVA 321
Y GL+YR+++ V WS + R+A+++ E+E P H + V F LL +A
Sbjct: 231 YDKGLVYRSYKPVFWSPSSRTALAEAELEYNP--EHVSRSIY-----VKFPLLKPSPKLA 283
Query: 322 FPVDGEPDAEVVVGTTRPETLPGDVAVAVHPDDSRY------------------------ 357
+DG ++V TT+P T+P + AV P+ S+Y
Sbjct: 284 SLIDGSSPVSILVWTTQPWTIPANEAVCYMPE-SKYAVVKCSKSGDLYVLAADKVASVAS 342
Query: 358 ---------THLHGRQLRHPLMGQPL------PLITDYAVQPHVGTGAVKVTPAHSPADA 402
+ L G L + PL PL+ V GTG V PAH D
Sbjct: 343 TLETTFETISTLSGVDLENGTCSHPLIPDKASPLLPANHVTMAKGTGLVHTAPAHGMEDY 402
Query: 403 EMGARHGLSPLNVIAEDGTMTSLCGDWLQGLHRFVAREKIMSVLSEWGLFRGLQNHPMVL 462
+ ++H L ++ EDG T + G LQ ++ V E V+ + L ++
Sbjct: 403 GVASQHNLPMDCLVDEDGVFTDVAGPELQ--NKAVLEEGTDVVIKMLQTAKNLLKEEKLV 460
Query: 463 ---PICSRSGDVIEYLLKNQWFVRCQEMGARAAKAVESGALELSPSFHQKNWQHWFSHIG 519
P R+ + QWF+ ++ A + ++ ++ P
Sbjct: 461 HSYPYDWRTKKPVVIRASKQWFINITDIKTAAKELLKK--VKFIPGSALNGMVEMMDRRP 518
Query: 520 DWCVSRQLWWGHQIPA--------YLV-----------VEDHAQGEEDCWVVGRSEAEAR 560
WC+SRQ WG IP YL+ VE H G + W + + +
Sbjct: 519 YWCISRQRVWGVPIPVFHHKTKDEYLINSQTTEHIVKLVEQH--GSDIWWTLPPEQLLPK 576
Query: 561 EVAAELTGRPGAELTLERDPDVLDTWFSSALFPFSALGWPQETPDLARFYPLSLLETGSD 620
EV +E+ G E +D +LD WF S L P + DL LE G D
Sbjct: 577 EVLSEVGGPDALEYVPGQD--ILDIWFDSGTSWSYVLPGPDQRADL-------YLE-GKD 626
Query: 621 LLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMSKSLGNVLDPRDIISGVEMQV 680
L W ++ + P+ V++H +G KMSKSLGNV+ P +++G + Q
Sbjct: 627 QLGGWFQSSLLTSVAARKRAPYKTVIVHGFTLGEKGEKMSKSLGNVIHPDVVVNGGQDQS 686
Query: 681 LQEKLRSGNLDPAELAIVAAAQKKDFPHGIPECGTDALRFTLCSHGVQAGDLHLSVSEVQ 740
+ P G D LR+ + V ++ + S +
Sbjct: 687 KE----------------------------PPYGADVLRWWVADSNVFT-EVAIGPSVLN 717
Query: 741 SCRHFCNKIWNALRFILNALGEKFVPQPAEELSPSSPMDAWILSRLALAAQECERGFLTR 800
+ R +K+ N LRF+L + + + ++ +D ++L L A + +
Sbjct: 718 AARDDISKLRNTLRFLLGNVADFNPETDSIPVNDMYVIDQYMLHLLQDLANKITELYKQY 777
Query: 801 ELSLVTHALHHFWLHNLCDVYLEAVKPVLW----HSPRPLGPPQVLFSCADLGLRLLAPL 856
+ V L F+ L + Y +K L+ + P+ L D+ +R AP+
Sbjct: 778 DFGKVVRLLRTFYTRELSNFYFSIIKDRLYCEKENDPKRRSCQTALVEILDVIVRSFAPI 837
Query: 857 MPFLAEELWQRLPPRPGCPPAPSISVAPYPSACSLEHWRQPELE 900
+P LAEE++Q + P S+ + S S+ W++P LE
Sbjct: 838 LPHLAEEVFQHI---PYIKEPKSVFRTGWISTSSI--WKKPGLE 876
>gi|94721239 isoleucine tRNA synthetase [Homo sapiens]
Length = 1262
Score = 122 bits (307), Expect = 1e-27
Identities = 145/600 (24%), Positives = 232/600 (38%), Gaps = 102/600 (17%)
Query: 145 PPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQAVVEKQLW----- 199
PP TG H GH L I+D + R+ G V G D G+ + ++K L
Sbjct: 47 PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPE 106
Query: 200 --KERGVRRHELS-REAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVA 256
+ G+ + R +R +WK + LG +D+D + T+ +
Sbjct: 107 DVAKMGITEYNNQCRAIVMRYSAEWKST--------VSRLGRWIDFDNDYKTLYPQFMES 158
Query: 257 VTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGHTQLRLPGCPTPVSFGL 316
V F +LY GL+YR +++ +S A + +S+ E + P F
Sbjct: 159 VWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE---------SHQNYKDVQDPSVF-- 207
Query: 317 LFSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPD----------------------- 353
V FP++ + +V TT P TLP ++AV V+P+
Sbjct: 208 ---VTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLS 264
Query: 354 -----DSRY--------THLHGRQLRHPLMGQPLP--------LITDYAVQPHVGTGAVK 392
+S Y +L G++ R PL L ++ D V+ GTG V
Sbjct: 265 ALYKLESDYEILERFPGAYLKGKKYR-PLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVH 323
Query: 393 VTPAHSPADAEMGA-----RHGLSPLNVIAEDGTMTSLCGDWLQGLHRFVAREKIMSVLS 447
P D + R P+ + G T+ D+ G + A + I+ L
Sbjct: 324 QAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFA-GQYVKDADKSIIRTLK 382
Query: 448 EWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQWFVRCQEMGARAAKAVESGALELSPSFH 507
E G P C RS + Y WFVR + M + + + +
Sbjct: 383 EQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDL-CYWVPELVR 441
Query: 508 QKNWQHWFSHIGDWCVSRQLWWGHQIPAYLVVEDHAQGEEDCWVVGRSEAEAREVA---- 563
+K + +W DW +SR +WG IP ++ + E+ +G S AE E++
Sbjct: 442 EKRFGNWLKDARDWTISRNRYWGTPIPLWV-----SDDFEEVVCIG-SVAELEELSGAKI 495
Query: 564 AELTGRPGAELT---------LERDPDVLDTWFSSALFPFSALGWPQETP-DLARFYPLS 613
++L LT L R +V D WF S P++ + +P E + +P
Sbjct: 496 SDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPAD 555
Query: 614 LLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMSKSLGNVLDPRDII 673
+ G D W +++L T L GQ PF V+++ +V G+KMSK N DP II
Sbjct: 556 FIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSII 615
>gi|94721241 isoleucine tRNA synthetase [Homo sapiens]
Length = 1262
Score = 122 bits (307), Expect = 1e-27
Identities = 145/600 (24%), Positives = 232/600 (38%), Gaps = 102/600 (17%)
Query: 145 PPNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGIATQAVVEKQLW----- 199
PP TG H GH L I+D + R+ G V G D G+ + ++K L
Sbjct: 47 PPFATGLPHYGHILAGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPE 106
Query: 200 --KERGVRRHELS-REAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVA 256
+ G+ + R +R +WK + LG +D+D + T+ +
Sbjct: 107 DVAKMGITEYNNQCRAIVMRYSAEWKST--------VSRLGRWIDFDNDYKTLYPQFMES 158
Query: 257 VTEAFVRLYKAGLLYRNHQLVNWSCALRSAISDIEVENRPLPGHTQLRLPGCPTPVSFGL 316
V F +LY GL+YR +++ +S A + +S+ E + P F
Sbjct: 159 VWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNFE---------SHQNYKDVQDPSVF-- 207
Query: 317 LFSVAFPVDGEPDAEVVVGTTRPETLPGDVAVAVHPD----------------------- 353
V FP++ + +V TT P TLP ++AV V+P+
Sbjct: 208 ---VTFPLEEDETVSLVAWTTTPWTLPSNLAVCVNPEMQYVKIKDVARGRLLILMEARLS 264
Query: 354 -----DSRY--------THLHGRQLRHPLMGQPLP--------LITDYAVQPHVGTGAVK 392
+S Y +L G++ R PL L ++ D V+ GTG V
Sbjct: 265 ALYKLESDYEILERFPGAYLKGKKYR-PLFDYFLKCKENGAFTVLVDNYVKEEEGTGVVH 323
Query: 393 VTPAHSPADAEMGA-----RHGLSPLNVIAEDGTMTSLCGDWLQGLHRFVAREKIMSVLS 447
P D + R P+ + G T+ D+ G + A + I+ L
Sbjct: 324 QAPYFGAEDYRVCMDFNIIRKDSLPVCPVDASGCFTTEVTDFA-GQYVKDADKSIIRTLK 382
Query: 448 EWGLFRGLQNHPMVLPICSRSGDVIEYLLKNQWFVRCQEMGARAAKAVESGALELSPSFH 507
E G P C RS + Y WFVR + M + + + +
Sbjct: 383 EQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRVENMVDQLLRNNDL-CYWVPELVR 441
Query: 508 QKNWQHWFSHIGDWCVSRQLWWGHQIPAYLVVEDHAQGEEDCWVVGRSEAEAREVA---- 563
+K + +W DW +SR +WG IP ++ + E+ +G S AE E++
Sbjct: 442 EKRFGNWLKDARDWTISRNRYWGTPIPLWV-----SDDFEEVVCIG-SVAELEELSGAKI 495
Query: 564 AELTGRPGAELT---------LERDPDVLDTWFSSALFPFSALGWPQETP-DLARFYPLS 613
++L LT L R +V D WF S P++ + +P E + +P
Sbjct: 496 SDLHRESVDHLTIPSRCGKGSLHRISEVFDCWFESGSMPYAQVHYPFENKREFEDAFPAD 555
Query: 614 LLETGSDLLLFWVGRMVMLGTQLTGQLPFSKVLLHPMVRDRQGRKMSKSLGNVLDPRDII 673
+ G D W +++L T L GQ PF V+++ +V G+KMSK N DP II
Sbjct: 556 FIAEGIDQTRGWFYTLLVLATALFGQPPFKNVIVNGLVLASDGQKMSKRKKNYPDPVSII 615
>gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo
sapiens]
Length = 903
Score = 67.4 bits (163), Expect = 7e-11
Identities = 44/149 (29%), Positives = 68/149 (45%), Gaps = 19/149 (12%)
Query: 146 PNVTGSLHIGHALTVAIQDALVRWHRMRGDQVLWVPGSDHAGI-ATQAVVEKQLWKERGV 204
P +G LH+GH I D + R+ +MRG QV+ G D G+ A A VE+ L +
Sbjct: 91 PYPSGKLHMGHVRVYTISDTIARFQKMRGMQVINPMGWDAFGLPAENAAVERNLHPQ--- 147
Query: 205 RRHELSREAFLREVWQWKEAKGGEICEQLRALGASLDWDRECFTMDVGSSVAVTEAFVRL 264
W ++ + +QL LG WDRE T F++L
Sbjct: 148 ---------------SWTQSNIKHMRKQLDRLGLCFSWDREITTCLPDYYKWTQYLFIKL 192
Query: 265 YKAGLLYRNHQLVNWSCALRSAISDIEVE 293
Y+AGL Y+ LVNW ++ +++ +V+
Sbjct: 193 YEAGLAYQKEALVNWDPVDQTVLANEQVD 221
>gi|74271888 lipin 3 [Homo sapiens]
Length = 851
Score = 35.8 bits (81), Expect = 0.22
Identities = 32/117 (27%), Positives = 49/117 (41%), Gaps = 8/117 (6%)
Query: 3 HLP--LASFRPPFWGLRHSRGLPRFHSVSTQSEPHGSPISRRNREAKQKRLREKQATLEA 60
H+P L + P+ GL G P + T SEP G ++ ++KR R ++ +
Sbjct: 98 HVPPGLCTSPIPWGGLS---GFPSDSQLGTASEPEGLVMAGTASTGRRKRRRRRKPKQKE 154
Query: 61 EIAGESKSPAESIKAWRPKELVLYE--IPTKPGEKKDVSGPLPPAYSPRYVEAAWYP 115
+ SP E ++A EL L E P PG + + L P Y + W P
Sbjct: 155 DAVATDSSP-EELEAGAESELSLPEKLRPEPPGVQLEEKSSLQPKDIYPYSDGEWPP 210
>gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]
Length = 593
Score = 35.8 bits (81), Expect = 0.22
Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 12/100 (12%)
Query: 579 DPDVLDTWFSSALFPFSALGWPQETPDLARFYPLSLLETGSDLL----LFWVGRMVMLGT 634
D + W + + + +G+P + ++P + G D+L ++W +LG
Sbjct: 272 DSQTIYVWLDALVNYLTVIGYPNA--EFKSWWPATSHIIGKDILKFHAIYWPA--FLLGA 327
Query: 635 QLTGQLPFSKVLLHPMVRDRQGRKMSKSLGNVLDPRDIIS 674
G P ++ +H G+KMSKSLGNV+DPR ++
Sbjct: 328 ---GMSPPQRICVHSHWTVC-GQKMSKSLGNVVDPRTCLN 363
>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta
subunit 2 isoform b [Homo sapiens]
Length = 1143
Score = 33.5 bits (75), Expect = 1.1
Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 29/122 (23%)
Query: 837 GPPQVLFSCADLGLRLLAPLMPFLAEELWQRLPPRPGCPPAPSISVAPYPSACSLEHW-R 895
GPP+ L+ LL PL+P LA AP S +P +++HW R
Sbjct: 39 GPPRPLW--------LLLPLLPLLA---------------APGASAYSFPQQHTMQHWAR 75
Query: 896 QPELE-----RRFSRVQEVVQVLRALRATYQLTKARPRVLLQSSEPGDQGLFEAFLEPLG 950
+ E E R F VQ++ ++ + R +++ + P+ L++ + L + ++ L
Sbjct: 76 RLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALK 135
Query: 951 TL 952
L
Sbjct: 136 RL 137
>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta
subunit 2 isoform a [Homo sapiens]
Length = 1145
Score = 33.5 bits (75), Expect = 1.1
Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 29/122 (23%)
Query: 837 GPPQVLFSCADLGLRLLAPLMPFLAEELWQRLPPRPGCPPAPSISVAPYPSACSLEHW-R 895
GPP+ L+ LL PL+P LA AP S +P +++HW R
Sbjct: 39 GPPRPLW--------LLLPLLPLLA---------------APGASAYSFPQQHTMQHWAR 75
Query: 896 QPELE-----RRFSRVQEVVQVLRALRATYQLTKARPRVLLQSSEPGDQGLFEAFLEPLG 950
+ E E R F VQ++ ++ + R +++ + P+ L++ + L + ++ L
Sbjct: 76 RLEQEVDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALK 135
Query: 951 TL 952
L
Sbjct: 136 RL 137
>gi|108773810 leucyl-tRNA synthetase [Homo sapiens]
Length = 1176
Score = 33.1 bits (74), Expect = 1.4
Identities = 19/80 (23%), Positives = 36/80 (45%)
Query: 117 WVREGFFKPEYQARLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDQ 176
W E F+ Q + + + P P + G LH+GH +++ + V + R++G
Sbjct: 24 WDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKC 83
Query: 177 VLWVPGSDHAGIATQAVVEK 196
L+ G G+ +A +K
Sbjct: 84 CLFPFGLHCTGMPIKACADK 103
>gi|13376259 nucleoporin 85 [Homo sapiens]
Length = 656
Score = 33.1 bits (74), Expect = 1.4
Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Query: 993 QIQLPLLAARRYKLQKQLDSLTARTPSEGEAGTQRQQ--KLSSLQLELSKLDKAASHLQQ 1050
Q Q+ A + Y+L + L+ LT+R P GE+ T++ Q + + ++E+ +L A + +
Sbjct: 587 QKQVIFSAEQTYELMRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARA 646
Query: 1051 LMDEPPAPGS 1060
++ E GS
Sbjct: 647 IIREGSLEGS 656
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 33.1 bits (74), Expect = 1.4
Identities = 28/103 (27%), Positives = 43/103 (41%), Gaps = 10/103 (9%)
Query: 868 LPPRPGCPPAPSISVAPYPSACSLEHWRQPELER-----RFSRVQEVVQVLRALRATYQL 922
+PP P PP P P P + QP+L R R + +Q++ + + + T
Sbjct: 3 IPPPPPPPPGP-----PPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNIN 57
Query: 923 TKARPRVLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGLLPPGA 965
++ P + G G A L+P G L G + L P GA
Sbjct: 58 DRSAPILEKPKGSSGGYGSGGAALQPKGGLFQGGVLKLRPVGA 100
>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
delta [Homo sapiens]
Length = 831
Score = 32.7 bits (73), Expect = 1.9
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Query: 825 VKPVLWHSPRPLGPPQVLFSCADLGLRLLAPLMPFLAEE-LWQRLPPRPGCPPAPSISVA 883
V P L H P P P L C +AP L EE L+ P P PPAP +S
Sbjct: 391 VPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPL 449
Query: 884 PYPSA 888
P P+A
Sbjct: 450 PAPAA 454
>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
gamma [Homo sapiens]
Length = 850
Score = 32.7 bits (73), Expect = 1.9
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Query: 825 VKPVLWHSPRPLGPPQVLFSCADLGLRLLAPLMPFLAEE-LWQRLPPRPGCPPAPSISVA 883
V P L H P P P L C +AP L EE L+ P P PPAP +S
Sbjct: 391 VPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPL 449
Query: 884 PYPSA 888
P P+A
Sbjct: 450 PAPAA 454
>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
beta [Homo sapiens]
Length = 833
Score = 32.7 bits (73), Expect = 1.9
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Query: 825 VKPVLWHSPRPLGPPQVLFSCADLGLRLLAPLMPFLAEE-LWQRLPPRPGCPPAPSISVA 883
V P L H P P P L C +AP L EE L+ P P PPAP +S
Sbjct: 391 VPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPL 449
Query: 884 PYPSA 888
P P+A
Sbjct: 450 PAPAA 454
>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
alpha [Homo sapiens]
Length = 852
Score = 32.7 bits (73), Expect = 1.9
Identities = 25/65 (38%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Query: 825 VKPVLWHSPRPLGPPQVLFSCADLGLRLLAPLMPFLAEE-LWQRLPPRPGCPPAPSISVA 883
V P L H P P P L C +AP L EE L+ P P PPAP +S
Sbjct: 391 VPPPLLHYPPPAKVPG-LEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGVSPL 449
Query: 884 PYPSA 888
P P+A
Sbjct: 450 PAPAA 454
>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
Length = 773
Score = 32.3 bits (72), Expect = 2.4
Identities = 27/77 (35%), Positives = 35/77 (45%), Gaps = 7/77 (9%)
Query: 32 SEPHGSPI-SRRNREAKQKRLREKQATLE-AEIAGESKSPAESIKAWRPKELVLYEIPTK 89
S P GSP S R + RL +K A + A IA S +P+ + KEL L E T
Sbjct: 264 SSPRGSPAHSPRENGLDKTRLLKKDAPISPASIASSSSTPSS-----KSKELSLNEKSTT 318
Query: 90 PGEKKDVSGPLPPAYSP 106
P K + P A +P
Sbjct: 319 PVSKSNTPTPRTDAPTP 335
>gi|4885185 distal-less homeobox 3 [Homo sapiens]
Length = 287
Score = 32.0 bits (71), Expect = 3.2
Identities = 27/110 (24%), Positives = 47/110 (42%), Gaps = 9/110 (8%)
Query: 42 RNREAKQKRL-REKQATLEAEIAGESKSPAESIKAWRPKELVLYEIP---TKPGEKKDVS 97
+NR +K K+L + + LE S + ++S+ P L++ T + +
Sbjct: 178 QNRRSKFKKLYKNGEVPLE-----HSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLP 232
Query: 98 GPLPPAYSPRYVEAAWYPWWVREGFFKPEYQARLPQATGETFSMCIPPPN 147
PLP + SP Y++ W+ + P Q + PQ + PPPN
Sbjct: 233 PPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPN 282
>gi|169214926 PREDICTED: similar to IQ motif and SEC7
domain-containing protein 3 [Homo sapiens]
Length = 185
Score = 32.0 bits (71), Expect = 3.2
Identities = 35/114 (30%), Positives = 44/114 (38%), Gaps = 9/114 (7%)
Query: 283 LRSAISDIEVENRPLPGHTQLRLPGCPTPVSFGLLFSVAFPVDGEPDAEVVVGTTRPETL 342
L + ++ ENR L H QL L P P GL+ + P+ P E L
Sbjct: 39 LERRLDELSTENRSLWEHQQL-LQAQPPP---GLVPPSSAPLPAAPATAPAAAARAQEPL 94
Query: 343 PGD---VAVAVHPDDSRYTHLH-GRQLRHPLMGQPLPLITDYAVQPHVGT-GAV 391
A A HP R H G+ L P G T + Q H+GT GAV
Sbjct: 95 QDQGQRSAAAPHPAPDRPPRQHHGQLLEQPQRGPGSRAHTPQSPQKHLGTQGAV 148
>gi|113428915 PREDICTED: similar to IQ motif and SEC7
domain-containing protein 3 [Homo sapiens]
Length = 185
Score = 32.0 bits (71), Expect = 3.2
Identities = 35/114 (30%), Positives = 44/114 (38%), Gaps = 9/114 (7%)
Query: 283 LRSAISDIEVENRPLPGHTQLRLPGCPTPVSFGLLFSVAFPVDGEPDAEVVVGTTRPETL 342
L + ++ ENR L H QL L P P GL+ + P+ P E L
Sbjct: 39 LERRLDELSTENRSLWEHQQL-LQAQPPP---GLVPPSSAPLPAAPATAPAAAARAQEPL 94
Query: 343 PGD---VAVAVHPDDSRYTHLH-GRQLRHPLMGQPLPLITDYAVQPHVGT-GAV 391
A A HP R H G+ L P G T + Q H+GT GAV
Sbjct: 95 QDQGQRSAAAPHPAPDRPPRQHHGQLLEQPQRGPGSRAHTPQSPQKHLGTQGAV 148
>gi|21359974 vitrin [Homo sapiens]
Length = 693
Score = 32.0 bits (71), Expect = 3.2
Identities = 39/158 (24%), Positives = 64/158 (40%), Gaps = 21/158 (13%)
Query: 878 PSISVAPYPSACSLEHWRQPELERRFSRVQEVVQVLRALRATYQLTKARPRVL--LQSSE 935
P+ P PSA S +P+ S+ ++ ATY ++ RPR +Q +
Sbjct: 197 PTTLPRPSPSAASTTSIPRPQSVGHRSQEMDLWST-----ATYTSSQNRPRADPGIQRQD 251
Query: 936 PGDQGLFEAFLEPLGTLGYCGAVGLLPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQ 995
P AF +P+G G + PG+ P + + +E L DP +
Sbjct: 252 PSGA----AFQKPVGADVSLGEMDSWKPGSVLLDE-GLVPKEELSTQSLEPVSLGDPNCK 306
Query: 996 LPL---------LAARRYKLQKQLDSLTARTPSEGEAG 1024
+ L + RR+++QKQL + A+ G AG
Sbjct: 307 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAG 344
>gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens]
Length = 1290
Score = 31.2 bits (69), Expect = 5.4
Identities = 24/100 (24%), Positives = 39/100 (39%)
Query: 869 PPRPGCPPAPSISVAPYPSACSLEHWRQPELERRFSRVQEVVQVLRALRATYQLTKARPR 928
PP+P PPAP AP S + + + +L + +V + R +
Sbjct: 450 PPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSP 509
Query: 929 VLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGLLPPGAAAP 968
L ++ G G+ + + PLG+ A LP A P
Sbjct: 510 ALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPP 549
>gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens]
Length = 1291
Score = 31.2 bits (69), Expect = 5.4
Identities = 24/100 (24%), Positives = 39/100 (39%)
Query: 869 PPRPGCPPAPSISVAPYPSACSLEHWRQPELERRFSRVQEVVQVLRALRATYQLTKARPR 928
PP+P PPAP AP S + + + +L + +V + R +
Sbjct: 450 PPQPTAPPAPPFPPAPPLSPQAGDSDLESQLAQSRKQVAKKSTSFRPGSVGSGHSSPTSP 509
Query: 929 VLLQSSEPGDQGLFEAFLEPLGTLGYCGAVGLLPPGAAAP 968
L ++ G G+ + + PLG+ A LP A P
Sbjct: 510 ALSENVSGGKPGINQTYRSPLGSTASAPAPSALPAPPAPP 549
>gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform a
[Homo sapiens]
Length = 565
Score = 30.8 bits (68), Expect = 7.1
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 811 HFWLHNLCDVY------LEAVKPVLWHSPRPLGPPQVLFSCADLGLRLLAPLMPFLAEEL 864
H W N ++ L+ ++P W G P +L +GL L+ L+ L
Sbjct: 110 HIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLL--- 166
Query: 865 WQRLPPRPGCPPAPS---ISVAPYPSACSLEHWRQPELERRF 903
R PP P P P SV+ PS + W + ++E F
Sbjct: 167 --RTPPEPPTPLPPEDRRQSVSRQPS-FTYSEWMEEKIEDDF 205
>gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform a
[Homo sapiens]
Length = 565
Score = 30.8 bits (68), Expect = 7.1
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 811 HFWLHNLCDVY------LEAVKPVLWHSPRPLGPPQVLFSCADLGLRLLAPLMPFLAEEL 864
H W N ++ L+ ++P W G P +L +GL L+ L+ L
Sbjct: 110 HIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLL--- 166
Query: 865 WQRLPPRPGCPPAPS---ISVAPYPSACSLEHWRQPELERRF 903
R PP P P P SV+ PS + W + ++E F
Sbjct: 167 --RTPPEPPTPLPPEDRRQSVSRQPS-FTYSEWMEEKIEDDF 205
>gi|24497609 nucleoporin 62kDa [Homo sapiens]
Length = 522
Score = 30.8 bits (68), Expect = 7.1
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
Query: 946 LEPLGTLGYCGAVGLLPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYK 1005
L P G A PPG A +G A + +A Y +L+ L++ + L L R+
Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAGAA----ASSAMTYAQLESLIN-KWSLELEDQERHF 351
Query: 1006 LQK--QLDSLTARTPSEGEAGTQRQQKLSSLQLELSKLDK 1043
LQ+ Q+++ GE T +++ ++L+ +LD+
Sbjct: 352 LQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQ 391
>gi|24497607 nucleoporin 62kDa [Homo sapiens]
Length = 522
Score = 30.8 bits (68), Expect = 7.1
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
Query: 946 LEPLGTLGYCGAVGLLPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYK 1005
L P G A PPG A +G A + +A Y +L+ L++ + L L R+
Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAGAA----ASSAMTYAQLESLIN-KWSLELEDQERHF 351
Query: 1006 LQK--QLDSLTARTPSEGEAGTQRQQKLSSLQLELSKLDK 1043
LQ+ Q+++ GE T +++ ++L+ +LD+
Sbjct: 352 LQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQ 391
>gi|24497605 nucleoporin 62kDa [Homo sapiens]
Length = 522
Score = 30.8 bits (68), Expect = 7.1
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
Query: 946 LEPLGTLGYCGAVGLLPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYK 1005
L P G A PPG A +G A + +A Y +L+ L++ + L L R+
Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAGAA----ASSAMTYAQLESLIN-KWSLELEDQERHF 351
Query: 1006 LQK--QLDSLTARTPSEGEAGTQRQQKLSSLQLELSKLDK 1043
LQ+ Q+++ GE T +++ ++L+ +LD+
Sbjct: 352 LQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQ 391
>gi|24497603 nucleoporin 62kDa [Homo sapiens]
Length = 522
Score = 30.8 bits (68), Expect = 7.1
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 7/100 (7%)
Query: 946 LEPLGTLGYCGAVGLLPPGAAAPSGWAQAPLSDTAQVYMELQGLVDPQIQLPLLAARRYK 1005
L P G A PPG A +G A + +A Y +L+ L++ + L L R+
Sbjct: 297 LAPAGIPSNTAAAVTAPPGPGAAAGAA----ASSAMTYAQLESLIN-KWSLELEDQERHF 351
Query: 1006 LQK--QLDSLTARTPSEGEAGTQRQQKLSSLQLELSKLDK 1043
LQ+ Q+++ GE T +++ ++L+ +LD+
Sbjct: 352 LQQATQVNAWDRTLIENGEKITSLHREVEKVKLDQKRLDQ 391
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,026,726
Number of Sequences: 37866
Number of extensions: 2422496
Number of successful extensions: 7941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 7870
Number of HSP's gapped (non-prelim): 69
length of query: 1063
length of database: 18,247,518
effective HSP length: 113
effective length of query: 950
effective length of database: 13,968,660
effective search space: 13270227000
effective search space used: 13270227000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.