Guide to the Human Genome
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Name: IARS Sequence: fasta or formatted (1262aa) NCBI GI: 94721239
Description:

isoleucine tRNA synthetase

Referenced in:

Small RNAs in RNA Processing
tRNA Enzymes

Other entries for this name:
alt mRNA [1262aa] isoleucine tRNA synthetase
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         63           2
 C cysteine            1.8         23           1
 D aspartate           5.5         69           2
 E glutamate           7.6         96           3
 F phenylalanine       4.6         58           2
 G glycine             5.2         66           2
 H histidine           1.7         22           1
 I isoleucine          5.3         67           2
 K lysine              6.6         83           2
 L leucine            10.9        138           3
 M methionine          2.1         27           1
 N asparagine          4.2         53           2
 P proline             4.8         61           2
 Q glutamine           3.8         48           2
 R arginine            5.1         64           3
 S serine              5.7         72           3
 T threonine           6.3         79           3
 V valine              8.0        101           2
 W tryptophan          1.6         20           2
 Y tyrosine            4.1         52           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   isoleucine tRNA synthetase 
IARS                  1.000   isoleucine tRNA synthetase 
IARS2                 0.102   mitochondrial isoleucine tRNA synthetase 
VARS                  0.049   valyl-tRNA synthetase 
VARS2                 0.038   valyl-tRNA synthetase 2, mitochondrial 
LARS2                 0.016   leucyl-tRNA synthetase 2, mitochondrial precursor [Ho...
LARS                  0.006   leucyl-tRNA synthetase 
MYH15                 0.005   myosin, heavy polypeptide 15 
MYH3                  0.004   myosin, heavy chain 3, skeletal muscle, embryonic [H...
MYH7B                 0.004   myosin, heavy polypeptide 7B, cardiac muscle, beta ...
MYH13                 0.004   myosin, heavy polypeptide 13, skeletal muscle [Homo...
ATF7IP2               0.004   activating transcription factor 7 interacting protei...
GCC2                  0.004   GRIP and coiled-coil domain-containing 2 
MYH8                  0.004   myosin, heavy chain 8, skeletal muscle, perinatal [...
SDCCAG8               0.004   serologically defined colon cancer antigen 8 
MYH2                  0.003   myosin, heavy chain 2, skeletal muscle, adult [Homo...
MYH2                  0.003   myosin, heavy chain 2, skeletal muscle, adult [Homo...
MYH1                  0.003   myosin, heavy chain 1, skeletal muscle, adult [Homo...
ZBTB40                0.003   zinc finger and BTB domain containing 40 
ZBTB40                0.003   zinc finger and BTB domain containing 40 
WDR87                 0.003   NYD-SP11 protein 
EVPL                  0.003   envoplakin 
MYH4                  0.003   myosin, heavy polypeptide 4, skeletal muscle 
LBA1                  0.003   lupus brain antigen 1 
CHD8                  0.003   chromodomain helicase DNA binding protein 8 
RFWD2                 0.002   ring finger and WD repeat domain 2 isoform a 
MYH7                  0.002   myosin, heavy chain 7, cardiac muscle, beta 
MARS                  0.002   methionyl-tRNA synthetase 
MARS2                 0.002   methionine-tRNA synthetase 2 precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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