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Search of human proteins with 55741719
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
(1516 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens] 3118 0.0
gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens] 3118 0.0
gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sap... 256 1e-67
gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap... 256 1e-67
gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapi... 256 1e-67
gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sap... 149 2e-35
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 2e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 62 3e-09
gi|55750053 atrophin-1 [Homo sapiens] 56 3e-07
gi|55750041 atrophin-1 [Homo sapiens] 56 3e-07
gi|169164209 PREDICTED: hypothetical protein [Homo sapiens] 54 1e-06
gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo ... 54 1e-06
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 54 1e-06
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 54 1e-06
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 3e-06
gi|150378539 piccolo isoform 1 [Homo sapiens] 52 3e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 52 3e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 52 6e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 52 6e-06
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens] 50 1e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 50 2e-05
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 49 3e-05
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 49 3e-05
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 49 3e-05
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 49 3e-05
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 49 3e-05
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 49 3e-05
gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 49 4e-05
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] 49 4e-05
gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens] 49 5e-05
>gi|209862765 RUN and SH3 domain containing 2 [Homo sapiens]
Length = 1516
Score = 3118 bits (8085), Expect = 0.0
Identities = 1516/1516 (100%), Positives = 1516/1516 (100%)
Query: 1 MDSPPKLTGETLIVHHIPLVHCQVPDRQCCGGAGGGGGSTRPNPFCPPELGITQPDQDLG 60
MDSPPKLTGETLIVHHIPLVHCQVPDRQCCGGAGGGGGSTRPNPFCPPELGITQPDQDLG
Sbjct: 1 MDSPPKLTGETLIVHHIPLVHCQVPDRQCCGGAGGGGGSTRPNPFCPPELGITQPDQDLG 60
Query: 61 QADSLLFSSLHSAPGGTARSIDSTKSRSRDGRGPGAPKRHNPFLLQEGVGEPGLGDLYDD 120
QADSLLFSSLHSAPGGTARSIDSTKSRSRDGRGPGAPKRHNPFLLQEGVGEPGLGDLYDD
Sbjct: 61 QADSLLFSSLHSAPGGTARSIDSTKSRSRDGRGPGAPKRHNPFLLQEGVGEPGLGDLYDD 120
Query: 121 SIGDSATQQSFHLHGTGQPNFHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQEPVMTL 180
SIGDSATQQSFHLHGTGQPNFHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQEPVMTL
Sbjct: 121 SIGDSATQQSFHLHGTGQPNFHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQEPVMTL 180
Query: 181 DTQQCGTSHCCRPELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSDESPRNP 240
DTQQCGTSHCCRPELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSDESPRNP
Sbjct: 181 DTQQCGTSHCCRPELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSDESPRNP 240
Query: 241 GCSGSGDQHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLN 300
GCSGSGDQHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLN
Sbjct: 241 GCSGSGDQHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLN 300
Query: 301 SAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPELD 360
SAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPELD
Sbjct: 301 SAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPELD 360
Query: 361 ANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSC 420
ANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSC
Sbjct: 361 ANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSC 420
Query: 421 SEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQV 480
SEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQV
Sbjct: 421 SEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQV 480
Query: 481 YTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRR 540
YTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRR
Sbjct: 481 YTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRR 540
Query: 541 VTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPM 600
VTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPM
Sbjct: 541 VTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPM 600
Query: 601 PLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANS 660
PLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANS
Sbjct: 601 PLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANS 660
Query: 661 HTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLY 720
HTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLY
Sbjct: 661 HTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLY 720
Query: 721 SLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSY 780
SLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSY
Sbjct: 721 SLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSY 780
Query: 781 SPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI 840
SPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI
Sbjct: 781 SPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI 840
Query: 841 LTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYR 900
LTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYR
Sbjct: 841 LTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYR 900
Query: 901 RKNPLGPPGLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPD 960
RKNPLGPPGLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPD
Sbjct: 901 RKNPLGPPGLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPD 960
Query: 961 FQDPFSLTEKPPAEFCLSPDGSSEAISIDLLQKKGLVKAVNIAVDLIVAHFGTSRDPGVK 1020
FQDPFSLTEKPPAEFCLSPDGSSEAISIDLLQKKGLVKAVNIAVDLIVAHFGTSRDPGVK
Sbjct: 961 FQDPFSLTEKPPAEFCLSPDGSSEAISIDLLQKKGLVKAVNIAVDLIVAHFGTSRDPGVK 1020
Query: 1021 AKLGNSSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGP 1080
AKLGNSSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGP
Sbjct: 1021 AKLGNSSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGP 1080
Query: 1081 STKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWG 1140
STKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWG
Sbjct: 1081 STKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWG 1140
Query: 1141 FLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHKELLRVSQDLLL 1200
FLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHKELLRVSQDLLL
Sbjct: 1141 FLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHKELLRVSQDLLL 1200
Query: 1201 SAHSTLQLARARGQEGPGDVDRAAQGERVKGVGASEGGEEEEEEEETEEVAEAAGGSGRA 1260
SAHSTLQLARARGQEGPGDVDRAAQGERVKGVGASEGGEEEEEEEETEEVAEAAGGSGRA
Sbjct: 1201 SAHSTLQLARARGQEGPGDVDRAAQGERVKGVGASEGGEEEEEEEETEEVAEAAGGSGRA 1260
Query: 1261 RWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNSSSEKKKGAGGGGPPQAPPPREG 1320
RWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNSSSEKKKGAGGGGPPQAPPPREG
Sbjct: 1261 RWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNSSSEKKKGAGGGGPPQAPPPREG 1320
Query: 1321 VVEGAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPS 1380
VVEGAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPS
Sbjct: 1321 VVEGAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPS 1380
Query: 1381 PGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRREPEPKESLQEPH 1440
PGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRREPEPKESLQEPH
Sbjct: 1381 PGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRREPEPKESLQEPH 1440
Query: 1441 SPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAY 1500
SPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAY
Sbjct: 1441 SPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAY 1500
Query: 1501 VTLTPTPSPTPGSSQN 1516
VTLTPTPSPTPGSSQN
Sbjct: 1501 VTLTPTPSPTPGSSQN 1516
>gi|55741719 RUN and SH3 domain containing 2 [Homo sapiens]
Length = 1516
Score = 3118 bits (8085), Expect = 0.0
Identities = 1516/1516 (100%), Positives = 1516/1516 (100%)
Query: 1 MDSPPKLTGETLIVHHIPLVHCQVPDRQCCGGAGGGGGSTRPNPFCPPELGITQPDQDLG 60
MDSPPKLTGETLIVHHIPLVHCQVPDRQCCGGAGGGGGSTRPNPFCPPELGITQPDQDLG
Sbjct: 1 MDSPPKLTGETLIVHHIPLVHCQVPDRQCCGGAGGGGGSTRPNPFCPPELGITQPDQDLG 60
Query: 61 QADSLLFSSLHSAPGGTARSIDSTKSRSRDGRGPGAPKRHNPFLLQEGVGEPGLGDLYDD 120
QADSLLFSSLHSAPGGTARSIDSTKSRSRDGRGPGAPKRHNPFLLQEGVGEPGLGDLYDD
Sbjct: 61 QADSLLFSSLHSAPGGTARSIDSTKSRSRDGRGPGAPKRHNPFLLQEGVGEPGLGDLYDD 120
Query: 121 SIGDSATQQSFHLHGTGQPNFHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQEPVMTL 180
SIGDSATQQSFHLHGTGQPNFHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQEPVMTL
Sbjct: 121 SIGDSATQQSFHLHGTGQPNFHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQEPVMTL 180
Query: 181 DTQQCGTSHCCRPELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSDESPRNP 240
DTQQCGTSHCCRPELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSDESPRNP
Sbjct: 181 DTQQCGTSHCCRPELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSDESPRNP 240
Query: 241 GCSGSGDQHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLN 300
GCSGSGDQHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLN
Sbjct: 241 GCSGSGDQHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLN 300
Query: 301 SAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPELD 360
SAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPELD
Sbjct: 301 SAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPELD 360
Query: 361 ANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSC 420
ANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSC
Sbjct: 361 ANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSC 420
Query: 421 SEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQV 480
SEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQV
Sbjct: 421 SEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQV 480
Query: 481 YTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRR 540
YTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRR
Sbjct: 481 YTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRR 540
Query: 541 VTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPM 600
VTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPM
Sbjct: 541 VTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPM 600
Query: 601 PLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANS 660
PLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANS
Sbjct: 601 PLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANS 660
Query: 661 HTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLY 720
HTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLY
Sbjct: 661 HTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLY 720
Query: 721 SLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSY 780
SLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSY
Sbjct: 721 SLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSY 780
Query: 781 SPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI 840
SPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI
Sbjct: 781 SPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI 840
Query: 841 LTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYR 900
LTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYR
Sbjct: 841 LTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYR 900
Query: 901 RKNPLGPPGLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPD 960
RKNPLGPPGLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPD
Sbjct: 901 RKNPLGPPGLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPD 960
Query: 961 FQDPFSLTEKPPAEFCLSPDGSSEAISIDLLQKKGLVKAVNIAVDLIVAHFGTSRDPGVK 1020
FQDPFSLTEKPPAEFCLSPDGSSEAISIDLLQKKGLVKAVNIAVDLIVAHFGTSRDPGVK
Sbjct: 961 FQDPFSLTEKPPAEFCLSPDGSSEAISIDLLQKKGLVKAVNIAVDLIVAHFGTSRDPGVK 1020
Query: 1021 AKLGNSSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGP 1080
AKLGNSSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGP
Sbjct: 1021 AKLGNSSVSPNVGHLVLKYLCPAVRAVLEDGLKAFVLDVIIGQRKNMPWSVVEASTQLGP 1080
Query: 1081 STKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWG 1140
STKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWG
Sbjct: 1081 STKVLHGLYNKVSQFPELTSHTMRFNAFILGLLNIRSLEFWFNHLYNHEDIIQTHYQPWG 1140
Query: 1141 FLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHKELLRVSQDLLL 1200
FLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHKELLRVSQDLLL
Sbjct: 1141 FLSAAHTVCPGLFEELLLLLQPLALLPFSLDLLFQHRLLQSGQQQRQHKELLRVSQDLLL 1200
Query: 1201 SAHSTLQLARARGQEGPGDVDRAAQGERVKGVGASEGGEEEEEEEETEEVAEAAGGSGRA 1260
SAHSTLQLARARGQEGPGDVDRAAQGERVKGVGASEGGEEEEEEEETEEVAEAAGGSGRA
Sbjct: 1201 SAHSTLQLARARGQEGPGDVDRAAQGERVKGVGASEGGEEEEEEEETEEVAEAAGGSGRA 1260
Query: 1261 RWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNSSSEKKKGAGGGGPPQAPPPREG 1320
RWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNSSSEKKKGAGGGGPPQAPPPREG
Sbjct: 1261 RWARGGQAGWWYQLMQSSQVYIDGSIEGSRFPRGSSNSSSEKKKGAGGGGPPQAPPPREG 1320
Query: 1321 VVEGAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPS 1380
VVEGAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPS
Sbjct: 1321 VVEGAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPS 1380
Query: 1381 PGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRREPEPKESLQEPH 1440
PGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRREPEPKESLQEPH
Sbjct: 1381 PGGIKWGHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRREPEPKESLQEPH 1440
Query: 1441 SPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAY 1500
SPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAY
Sbjct: 1441 SPALPSSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAY 1500
Query: 1501 VTLTPTPSPTPGSSQN 1516
VTLTPTPSPTPGSSQN
Sbjct: 1501 VTLTPTPSPTPGSSQN 1516
>gi|157412249 RUN and SH3 domain containing 1 isoform c [Homo sapiens]
Length = 492
Score = 256 bits (654), Expect = 1e-67
Identities = 187/516 (36%), Positives = 250/516 (48%), Gaps = 102/516 (19%)
Query: 992 QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051
QKKGL+ AV+++VD I++HFG +R+ KA+LG+S +SP+VGHLVL LCPA+ A++ DG
Sbjct: 73 QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 132
Query: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111
LK F D+I GQR++ PWSVVEAS + G ST+ L LY++VS+ L+S RF+AFILG
Sbjct: 133 LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 192
Query: 1112 LLNIRSLEFWFNHLYNHEDIIQTHYQPWGFLSAAHTVCPGLFEELLLLLQPLALLPFSLD 1171
LLN + LE WF+ L ++ Y P GF S A CP L ELLLLLQPL++L F LD
Sbjct: 193 LLNTKQLELWFSSLQEDAGLLSLLYLPTGFFSLARGGCPSLSTELLLLLQPLSVLTFHLD 252
Query: 1172 LLFQHRLLQSGQQQRQHKELLRVSQDLLLSAHSTLQLARARGQEGPGDVDRAAQGERVKG 1231
LLF+H H L L + PG Q +
Sbjct: 253 LLFEH--------------------------HHHLPLGPPQAPAPPGPPPALQQTMQAM- 285
Query: 1232 VGASEGGEEEEEEEETEEVAEAAGGSGRARWARGGQAGWWYQLMQSSQVYIDGSIEG--- 1288
GG + T + A A+ S G WW QL Q+S+VY G EG
Sbjct: 286 --LHFGGRLAQSLRGTSKEA-ASDPSDSPNLPTPG--SWWEQLTQASRVYASGGTEGFPL 340
Query: 1289 SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAEACPASEEALGRERGWPFWMGSP 1348
SR+ G +++E EGA+ P + + RG W+G
Sbjct: 341 SRWAPGRHGTAAE---------------------EGAQERPLPTDEMAPGRG--LWLG-- 375
Query: 1349 PDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKWGHLFGSRKAQREARPTNRLPSD 1408
G PAENE GA + +R PS
Sbjct: 376 ------------RLFGVPGGPAENENGALK------------------------SRRPSS 399
Query: 1409 WLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALPSSPPCEVQALCHHLATGPGQLS 1467
WL S+ LV + G+ E P P+E E +P + + V+ALC H A P QLS
Sbjct: 400 WLPPTVSVLALVKR--GAPPEMPSPQE--LEASAPRMVQTHRA-VRALCDHTAARPDQLS 454
Query: 1468 FHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503
F +G++LRV+ DWLRC R GLVP+ Y +L
Sbjct: 455 FRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 490
>gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sapiens]
Length = 902
Score = 256 bits (654), Expect = 1e-67
Identities = 187/516 (36%), Positives = 250/516 (48%), Gaps = 102/516 (19%)
Query: 992 QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051
QKKGL+ AV+++VD I++HFG +R+ KA+LG+S +SP+VGHLVL LCPA+ A++ DG
Sbjct: 483 QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 542
Query: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111
LK F D+I GQR++ PWSVVEAS + G ST+ L LY++VS+ L+S RF+AFILG
Sbjct: 543 LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 602
Query: 1112 LLNIRSLEFWFNHLYNHEDIIQTHYQPWGFLSAAHTVCPGLFEELLLLLQPLALLPFSLD 1171
LLN + LE WF+ L ++ Y P GF S A CP L ELLLLLQPL++L F LD
Sbjct: 603 LLNTKQLELWFSSLQEDAGLLSLLYLPTGFFSLARGGCPSLSTELLLLLQPLSVLTFHLD 662
Query: 1172 LLFQHRLLQSGQQQRQHKELLRVSQDLLLSAHSTLQLARARGQEGPGDVDRAAQGERVKG 1231
LLF+H H L L + PG Q +
Sbjct: 663 LLFEH--------------------------HHHLPLGPPQAPAPPGPPPALQQTMQAM- 695
Query: 1232 VGASEGGEEEEEEEETEEVAEAAGGSGRARWARGGQAGWWYQLMQSSQVYIDGSIEG--- 1288
GG + T + A A+ S G WW QL Q+S+VY G EG
Sbjct: 696 --LHFGGRLAQSLRGTSKEA-ASDPSDSPNLPTPG--SWWEQLTQASRVYASGGTEGFPL 750
Query: 1289 SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAEACPASEEALGRERGWPFWMGSP 1348
SR+ G +++E EGA+ P + + RG W+G
Sbjct: 751 SRWAPGRHGTAAE---------------------EGAQERPLPTDEMAPGRG--LWLG-- 785
Query: 1349 PDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKWGHLFGSRKAQREARPTNRLPSD 1408
G PAENE GA + +R PS
Sbjct: 786 ------------RLFGVPGGPAENENGALK------------------------SRRPSS 809
Query: 1409 WLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALPSSPPCEVQALCHHLATGPGQLS 1467
WL S+ LV + G+ E P P+E E +P + + V+ALC H A P QLS
Sbjct: 810 WLPPTVSVLALVKR--GAPPEMPSPQE--LEASAPRMVQTHRA-VRALCDHTAARPDQLS 864
Query: 1468 FHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503
F +G++LRV+ DWLRC R GLVP+ Y +L
Sbjct: 865 FRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 900
>gi|42476123 RUN and SH3 domain containing 1 isoform d [Homo sapiens]
Length = 433
Score = 256 bits (654), Expect = 1e-67
Identities = 187/516 (36%), Positives = 250/516 (48%), Gaps = 102/516 (19%)
Query: 992 QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051
QKKGL+ AV+++VD I++HFG +R+ KA+LG+S +SP+VGHLVL LCPA+ A++ DG
Sbjct: 14 QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 73
Query: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111
LK F D+I GQR++ PWSVVEAS + G ST+ L LY++VS+ L+S RF+AFILG
Sbjct: 74 LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 133
Query: 1112 LLNIRSLEFWFNHLYNHEDIIQTHYQPWGFLSAAHTVCPGLFEELLLLLQPLALLPFSLD 1171
LLN + LE WF+ L ++ Y P GF S A CP L ELLLLLQPL++L F LD
Sbjct: 134 LLNTKQLELWFSSLQEDAGLLSLLYLPTGFFSLARGGCPSLSTELLLLLQPLSVLTFHLD 193
Query: 1172 LLFQHRLLQSGQQQRQHKELLRVSQDLLLSAHSTLQLARARGQEGPGDVDRAAQGERVKG 1231
LLF+H H L L + PG Q +
Sbjct: 194 LLFEH--------------------------HHHLPLGPPQAPAPPGPPPALQQTMQAM- 226
Query: 1232 VGASEGGEEEEEEEETEEVAEAAGGSGRARWARGGQAGWWYQLMQSSQVYIDGSIEG--- 1288
GG + T + A A+ S G WW QL Q+S+VY G EG
Sbjct: 227 --LHFGGRLAQSLRGTSKEA-ASDPSDSPNLPTPG--SWWEQLTQASRVYASGGTEGFPL 281
Query: 1289 SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAEACPASEEALGRERGWPFWMGSP 1348
SR+ G +++E EGA+ P + + RG W+G
Sbjct: 282 SRWAPGRHGTAAE---------------------EGAQERPLPTDEMAPGRG--LWLG-- 316
Query: 1349 PDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKWGHLFGSRKAQREARPTNRLPSD 1408
G PAENE GA + +R PS
Sbjct: 317 ------------RLFGVPGGPAENENGALK------------------------SRRPSS 340
Query: 1409 WLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALPSSPPCEVQALCHHLATGPGQLS 1467
WL S+ LV + G+ E P P+E E +P + + V+ALC H A P QLS
Sbjct: 341 WLPPTVSVLALVKR--GAPPEMPSPQE--LEASAPRMVQTHRA-VRALCDHTAARPDQLS 395
Query: 1468 FHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503
F +G++LRV+ DWLRC R GLVP+ Y +L
Sbjct: 396 FRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 431
>gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sapiens]
Length = 796
Score = 149 bits (376), Expect = 2e-35
Identities = 75/134 (55%), Positives = 102/134 (76%)
Query: 992 QKKGLVKAVNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNVGHLVLKYLCPAVRAVLEDG 1051
QKKGL+ AV+++VD I++HFG +R+ KA+LG+S +SP+VGHLVL LCPA+ A++ DG
Sbjct: 483 QKKGLLIAVSVSVDKIISHFGAARNLVQKAQLGDSRLSPDVGHLVLTTLCPALHALVADG 542
Query: 1052 LKAFVLDVIIGQRKNMPWSVVEASTQLGPSTKVLHGLYNKVSQFPELTSHTMRFNAFILG 1111
LK F D+I GQR++ PWSVVEAS + G ST+ L LY++VS+ L+S RF+AFILG
Sbjct: 543 LKPFRKDLITGQRRSSPWSVVEASVKPGSSTRSLGTLYSQVSRLAPLSSSRSRFHAFILG 602
Query: 1112 LLNIRSLEFWFNHL 1125
LLN + LE WF+ L
Sbjct: 603 LLNTKQLELWFSSL 616
Score = 84.7 bits (208), Expect = 6e-16
Identities = 73/238 (30%), Positives = 99/238 (41%), Gaps = 70/238 (29%)
Query: 1270 WWYQLMQSSQVYIDGSIEG---SRFPRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAE 1326
WW QL Q+S+VY G EG SR+ G +++E EGA+
Sbjct: 623 WWEQLTQASRVYASGGTEGFPLSRWAPGRHGTAAE---------------------EGAQ 661
Query: 1327 ACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAASPAENEEGASEPSPGGIKW 1386
P + + RG W+G G PAENE GA +
Sbjct: 662 ERPLPTDEMAPGRG--LWLG--------------RLFGVPGGPAENENGALK-------- 697
Query: 1387 GHLFGSRKAQREARPTNRLPSDWLSLDKSMFQLVAQTVGSRRE-PEPKESLQEPHSPALP 1445
+R PS WL S+ LV + G+ E P P+E E +P +
Sbjct: 698 ----------------SRRPSSWLPPTVSVLALVKR--GAPPEMPSPQEL--EASAPRMV 737
Query: 1446 SSPPCEVQALCHHLATGPGQLSFHKGDILRVLGRAGGDWLRCSRGPDSGLVPLAYVTL 1503
+ V+ALC H A P QLSF +G++LRV+ DWLRC R GLVP+ Y +L
Sbjct: 738 QTHRA-VRALCDHTAARPDQLSFRRGEVLRVITTVDEDWLRCGRDGMEGLVPVGYTSL 794
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 62.8 bits (151), Expect = 2e-09
Identities = 108/447 (24%), Positives = 149/447 (33%), Gaps = 116/447 (25%)
Query: 412 PAGSSITSCSEEHTKISPPPGPGPD----------PGPSQPSEYYLFQKPEVQPEEQEAV 461
PA S++S + T +S P GP P +P + P+V P ++A
Sbjct: 237 PASRSLSSSA---TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA- 292
Query: 462 SSSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCP 521
A A+GP LS+ + S +LQ P L + S
Sbjct: 293 ------APALGP---------------LSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331
Query: 522 VRLSEG-PAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQ 580
+L+ P A P +PP T SPP +P +A
Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTL--------------PSPPA-----------TPPSQAT 366
Query: 581 QDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPP--AGLRAT 638
G+P + T HS P P P P +T Q P + +PP A
Sbjct: 367 TSLGSPTLQAT---HSFLPSP-----------PLSPLATPPPQAPPALALPPLQAPPSPP 412
Query: 639 GQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFV 698
PL+ L P P P + A Q A S PV + P + P+ P
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQ------APFSPPPSPPV--QAPFSPPASPPVSPSA 464
Query: 699 FQHHFPKQLAKARALHSL--------SQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEP 750
P Q + A L S S S Q P PLAAP Q++ P P P
Sbjct: 465 TP---PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 751 QASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTA 810
+TP P + PSP S+ PF PS S +PPP+ P
Sbjct: 522 ALATP-------------PLQALPSPPASFP---GQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 811 TES----LPPWSHSCPSAVRPATSQQP 833
+ +PP + P+ P P
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPRRPPTP 592
Score = 39.3 bits (90), Expect = 0.029
Identities = 112/487 (22%), Positives = 157/487 (32%), Gaps = 77/487 (15%)
Query: 507 PPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSV 566
PPV +L R+L + P A G + A A + G S P
Sbjct: 37 PPVTPAAL-RVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPP 95
Query: 567 GDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGP-GMDLLGPDPSPPWSTQVCQGP 625
E +P A+ P+ S + P PLG G+ + + + + P
Sbjct: 96 ASGRGERAP--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA--RGKATEAP 151
Query: 626 HSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSK 685
S + AG R GP PG+P+ + +R A + G P S
Sbjct: 152 KRSALS-AGARRDTSGPT----------PGTPSPAMARRSRAAGTEVGLPRPAP----SA 196
Query: 686 EQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSL-----SGCSRTQQPAP--LAAPA 738
RP T P++ + + HS ++ S Q+PA L++ A
Sbjct: 197 RPRPPT----------EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 739 AQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGP-FGPSTDSSA 797
+S PA SG TPRA ++ + RP + P + P GP + S
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP--PRKDAAPALGPLSSSPL 304
Query: 798 STSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKILTLTEYRLHGTGSLPPL 857
+T Q A +LP HS + AT L L PP
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATP----------LPLA----------PPS 344
Query: 858 GSWRSGLSRAESLARGGGEGSMATRPSNANHL--SPQALKWREYRRKNPLGPPGLSGSLD 915
S L S AT PS A SP + PL P L
Sbjct: 345 PSAPPSLQTLPS--------PPATPPSQATTSLGSPTLQATHSFLPSPPLSP------LA 390
Query: 916 RRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPDFQDPFSLTEKPPAEF 975
+A A P + P S A+ L+ P L Q PFS PP +
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 976 CLSPDGS 982
SP S
Sbjct: 451 PFSPPAS 457
Score = 38.9 bits (89), Expect = 0.038
Identities = 60/267 (22%), Positives = 94/267 (35%), Gaps = 21/267 (7%)
Query: 736 APAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVG---PFGPS 792
A +V +P P+ + P R + + SE T+ PSP P G P S
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
Query: 793 TDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKIL---TLTEYRLH 849
SSA+ SP P+A P A PA QP+ + + L +T R
Sbjct: 242 LSSSATPLSSPARSGPSA--------RGTPRA--PAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 850 GTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYRRKNPLGPPG 909
+L PL S + + ++ P +++ L+ Q +P PP
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATP-HSSSLTCQLATPLPLAPPSPSAPPS 350
Query: 910 LS---GSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPDFQDPFS 966
L +A + +P + S + L+ P L P Q P S
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410
Query: 967 LTEKPPAEFCLSPDGSS-EAISIDLLQ 992
PP +P + A+++ LLQ
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQ 437
Score = 34.3 bits (77), Expect = 0.94
Identities = 88/419 (21%), Positives = 128/419 (30%), Gaps = 85/419 (20%)
Query: 404 LSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSS 463
LS ++PSP + + SPPP P P P F P P VS
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAP--------FSPPASPP-----VSP 462
Query: 464 STQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVR 523
S + P++ + SPP SPP+
Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPP-----------------ASPPM-------------- 491
Query: 524 LSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDR 583
P+A P +PP +LAK + + + P ++ F
Sbjct: 492 ---SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
Query: 584 GAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGP- 642
P+ PP+ P LL PSPP ++ Q P P G + GP
Sbjct: 549 SLPMSPLATPPPQAPPVLAAP---LLQVPPSPP-ASPTLQAPR--RPPTPGPDTSVSGPR 602
Query: 643 LAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHH 702
L + PGP P S + S T S P + P
Sbjct: 603 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP------------- 649
Query: 703 FPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGA 762
+ A + ++L + + ++ PAP A P P P ATG G+
Sbjct: 650 ---EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-------WPPATGPGS 699
Query: 763 RKA------GSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLP 815
PE++ P+P G+ P S G G + A S + LP
Sbjct: 700 ADGLCTIYETEGPESATPAP-GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 757
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 62.4 bits (150), Expect = 3e-09
Identities = 109/444 (24%), Positives = 147/444 (33%), Gaps = 91/444 (20%)
Query: 434 GPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGP--TVLEGQVYTNTSPPNLST 491
GP PG P+ + + S+ GP +V ++ T P S
Sbjct: 157 GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SP 213
Query: 492 GRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSP-------------- 537
+R S LQR L S LS P R GP+A P +P
Sbjct: 214 AARRRPSAGGGLQRPASRSLSSSATPLSSPAR--SGPSARGTPRAPAHPSQPKPKGLQAL 271
Query: 538 -PRRVT--------SFAELAKGRKKTGGSGSPPLRVSVGDSSQEF-----SPIQEAQQDR 583
P +VT + L+ T +PP S S Q +P +A
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP-SPSAPPSLQTLPSPPATPPSQATTSL 330
Query: 584 GAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPP--AGLRATGQG 641
G+P + T HS P P P P +T Q P + +PP A
Sbjct: 331 GSPTLQAT---HSFLPSP-----------PLSPLATPPPQAPPALALPPLQAPPSPPASP 376
Query: 642 PLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQH 701
PL+ L P P P + A Q A S PV + P + P+ P
Sbjct: 377 PLSPLATPSPQAPNALAVHLLQ------APFSPPPSPPV--QAPFSPPASPPVSPSATP- 427
Query: 702 HFPKQLAKARALHSL--------SQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQAS 753
P Q + A L S S S Q P PLAAP Q++ P P P +
Sbjct: 428 --PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 485
Query: 754 TPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATES 813
TP P + PSP S+ PF PS S +PPP+ P +
Sbjct: 486 TP-------------PLQALPSPPASFP---GQAPFSPSASLPMSPLATPPPQAPPVLAA 529
Query: 814 ----LPPWSHSCPSAVRPATSQQP 833
+PP + P+ P P
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTP 553
Score = 48.5 bits (114), Expect = 5e-05
Identities = 83/367 (22%), Positives = 118/367 (32%), Gaps = 55/367 (14%)
Query: 521 PVRLSEGPAAMAGPGSPPRRVTSFAEL-----AKGRKKTGGSGSPPLRVSVGDSSQEFSP 575
P R S PA+ G +PP + TS + A G + G G LR+S ++
Sbjct: 79 PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138
Query: 576 IQE---------AQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPS---------PPW 617
+ A++D P + + G + L P PS P
Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198
Query: 618 STQVCQGPHSSEMPPAGLRATGQG-----PLAQLMDPGPALPGSPANSHTQRDARARADG 672
S ++E PA R G P ++ + SPA S RA
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258
Query: 673 GGTESRP----------VLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSL 722
++ +P V K+ P P+ P A SL L S
Sbjct: 259 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP 318
Query: 723 SGCSRTQQPAPLAAPAAQVS---VPAPSGEPQAS----TPRATGRGARKAGSEPETSRP- 774
+Q L +P Q + +P+P P A+ P A +A P S P
Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378
Query: 775 SPLGSYSPIRS--------VGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVR 826
SPL + SP PF P SPP P + + PP S + PS
Sbjct: 379 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP-SQAPPSLAA 437
Query: 827 PATSQQP 833
P P
Sbjct: 438 PPLQVPP 444
Score = 46.2 bits (108), Expect = 2e-04
Identities = 106/431 (24%), Positives = 143/431 (33%), Gaps = 82/431 (19%)
Query: 597 LPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLR------ATGQGPLAQLMDP- 649
L P P G P P PP + PA LR A G+ PLA+
Sbjct: 25 LTPRPPG------SPRPPPP-------------VTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 650 -GPALPGSPANSHTQRDARARADGGGTESRPVL-----------RYSKEQRPTTLPIQPF 697
G +P S + R +R A G G + P R S RP P+
Sbjct: 66 GGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PLGQK 123
Query: 698 VFQHHFPKQLAKARALHSLSQLYSLSGCSR-TQQPAP----------LAAPAAQVSVPAP 746
+ + +A+ +A + + +G R T P P A +V +P P
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183
Query: 747 SGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVG---PFGPSTDSSASTSCSP 803
+ + P R + + SE T+ PSP P G P S SSA+ SP
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 804 PPEQPTATESLPPWSHSCPS--------AVRPATSQQPQKEDQKILTLTEYRLHGTGS-- 853
P+A + P + + PS A+RP P+K+ L T S
Sbjct: 244 ARSGPSARGT--PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301
Query: 854 LPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHL--SPQALKWREYRRKNPLGPPGLS 911
PP S L S AT PS A SP + PL P
Sbjct: 302 APPSPSAPPSLQTLPS--------PPATPPSQATTSLGSPTLQATHSFLPSPPLSP---- 349
Query: 912 GSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPDFQDPFSLTEKP 971
L +A A P + P S A+ L+ P L Q PFS P
Sbjct: 350 --LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407
Query: 972 PAEFCLSPDGS 982
P + SP S
Sbjct: 408 PVQAPFSPPAS 418
Score = 45.1 bits (105), Expect = 5e-04
Identities = 116/487 (23%), Positives = 149/487 (30%), Gaps = 103/487 (21%)
Query: 431 PGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLS 490
P P P PS P P P +QA ++G L+ SPP
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATP--------PSQATTSLGSPTLQATHSFLPSPP--- 346
Query: 491 TGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKG 550
S Q P + L L+ S P P A P +P +
Sbjct: 347 ----LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ---- 398
Query: 551 RKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLG 610
SPP++ FSP A S + PP+ + P
Sbjct: 399 -APFSPPPSPPVQA-------PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP-----S 445
Query: 611 PDPSPPWS---TQVCQGPHSSEMPPAGL-RATGQGPLAQLMDPGPALPGSPANSHTQRDA 666
P SPP S T Q P PP L + Q P A P ALP PA+ Q
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505
Query: 667 RARAD-------GGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQL 719
A ++ PVL Q P + P P
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP----------------------- 542
Query: 720 YSLSGCSRTQQPAP---LAAPAAQVSVPAPSGEPQASTPRATGRGARKAG-SEPETSRPS 775
+L R P P ++ P +++ P + +P +T G AG S TS P
Sbjct: 543 -TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPE 601
Query: 776 PLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSH--SCPSAVR------- 826
L Y GP G + SPPP+ A WS + P A R
Sbjct: 602 ELRGYDS----GPEG-------GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 650
Query: 827 ---PATSQQPQKEDQKILTLTEYRLHGTGSLPPL-GSWRSGLSRAES---LARGGGEGSM 879
PAT P D T Y G S P G+ G S S A G G G+
Sbjct: 651 PWPPATG--PGSADG---LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 705
Query: 880 ATRPSNA 886
+ P A
Sbjct: 706 SRSPKQA 712
Score = 34.3 bits (77), Expect = 0.94
Identities = 88/419 (21%), Positives = 128/419 (30%), Gaps = 85/419 (20%)
Query: 404 LSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSS 463
LS ++PSP + + SPPP P P P F P P VS
Sbjct: 378 LSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAP--------FSPPASPP-----VSP 423
Query: 464 STQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVR 523
S + P++ + SPP SPP+
Sbjct: 424 SATPPSQAPPSLAAPPLQVPPSPP-----------------ASPPM-------------- 452
Query: 524 LSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDR 583
P+A P +PP +LAK + + + P ++ F
Sbjct: 453 ---SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 584 GAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGP- 642
P+ PP+ P LL PSPP ++ Q P P G + GP
Sbjct: 510 SLPMSPLATPPPQAPPVLAAP---LLQVPPSPP-ASPTLQAPR--RPPTPGPDTSVSGPR 563
Query: 643 LAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHH 702
L + PGP P S + S T S P + P
Sbjct: 564 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP------------- 610
Query: 703 FPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGA 762
+ A + ++L + + ++ PAP A P P P ATG G+
Sbjct: 611 ---EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-------WPPATGPGS 660
Query: 763 RKA------GSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLP 815
PE++ P+P G+ P S G G + A S + LP
Sbjct: 661 ADGLCTIYETEGPESATPAP-GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 718
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 55.8 bits (133), Expect = 3e-07
Identities = 121/509 (23%), Positives = 163/509 (32%), Gaps = 121/509 (23%)
Query: 429 PPP--GPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSP 486
PPP P P P S P ++PE E +V+ + A PT Q P
Sbjct: 161 PPPLFPPSPQPPDSTP------RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 487 PNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAE 546
P+ P + G +LS P +G A + G P
Sbjct: 215 PH------------------PQLYPGGTGGVLSGPPMGPKGGGAASSVGGP--------- 247
Query: 547 LAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGM 606
GG PP + SS S GAP + P P+G G
Sbjct: 248 -------NGGKQHPPPTTPISVSSSGAS---------GAPPTKP-------PTTPVGGGN 284
Query: 607 DLLGPDPSPPWSTQVCQGPHSSEM--PPAGLRATGQGPLAQLMDPGPALPGSPANSHTQR 664
P P+ PH + PP LR PL P L P H
Sbjct: 285 LPSAPPPA--------NFPHVTPNLPPPPALR-----PLNNASASPPGLGAQPLPGHLPS 331
Query: 665 D-ARARADGG---GTESRPVLRYSKEQRP---TTLPIQPFVFQHHFPKQLAKARALHSLS 717
A + GG G E P L S P ++ P P F + + A + S S
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 718 QLYSLSGCSRTQQPAPLAAPAAQVSVPAPSG------EPQASTPRATGRGARKAGSEPET 771
S S + PA A P+ S P P+ P+ + P + G P
Sbjct: 392 -----SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP-- 444
Query: 772 SRPSPLGSYSPIRSV--GPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPAT 829
P P G + GPF PST A ++ PP +H +
Sbjct: 445 --PPPYGRLLANSNAHPGPFPPST--GAQSTAHPPVS-----------THHHHHQQQQQQ 489
Query: 830 SQQPQKEDQKILTLTEYRLHGTGSLPPLGSWRSGLS-----RAESLARGGGEGSMATRPS 884
QQ Q++ Q+ + + HG PP G++ L A A GS+ P
Sbjct: 490 QQQQQQQQQQ-----QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP 544
Query: 885 NANHLSPQALKWREYRRKNPLGPPGLSGS 913
HL P + Y + P GPP S S
Sbjct: 545 GPAHLPPPHSQ-VSYSQAGPNGPPVSSSS 572
Score = 48.5 bits (114), Expect = 5e-05
Identities = 103/438 (23%), Positives = 139/438 (31%), Gaps = 81/438 (18%)
Query: 478 GQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPV-RLGSLERMLSCPVRLSEGPAAMAGPGS 536
G V T++S RQ ++ +P V + G E + + P
Sbjct: 36 GGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQE 95
Query: 537 PPR-RVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQE---FSPIQ-EAQQDRGAPLDEGT 591
PR + S + GR S P + + S +SP E D + L +G
Sbjct: 96 LPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP 155
Query: 592 CCSHSLPPMPLGPGMDLLGPDPSPPWST----QVCQGPHSSEMPPAGLRATGQGPLAQLM 647
+ PP L P P PP ST + PH S + P G A + P +++
Sbjct: 156 ARPYHPPP--------LFPPSPQPPDSTPRQPEASFEPHPS-VTPTGYHAPMEPPTSRMF 206
Query: 648 DPGPALP----------------GSPANSHTQRDARARADGGGTESRP-------VLRYS 684
P P G P A + G + P V
Sbjct: 207 QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
Query: 685 KEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPA--AQVS 742
P T P V + P A H L P P P A S
Sbjct: 267 ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL----------PPPPALRPLNNASAS 316
Query: 743 VPAPSGEP---QASTPRATGRGARKAGSEPE---TSRPSPLGSYSPIRSVGPFGP----- 791
P +P +P A G+G PE T PSP S P S P P
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP-HSLPPASSSAPAPPMRFPY 375
Query: 792 -----------STDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI 840
S+ SS+S+S SP P A+++LP + HS P + S QP K Q
Sbjct: 376 SSSSSSSAAASSSSSSSSSSASPFP----ASQALPSYPHSFPPPTSLSVSNQPPKYTQPS 431
Query: 841 LTLTEYRLHGTGSLPPLG 858
L G PP G
Sbjct: 432 LPSQAVWSQGPPPPPPYG 449
Score = 42.4 bits (98), Expect = 0.003
Identities = 116/527 (22%), Positives = 169/527 (32%), Gaps = 115/527 (21%)
Query: 347 GGYGCPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSS 406
GG P A P AN P+ P PA+ L S L + L S
Sbjct: 281 GGGNLPSAPPP---ANFPHVTPNLPPPPALRPLNNASASPPGLGAQP------LPGHLPS 331
Query: 407 QSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQ 466
+ + E+ ++P P P S P+ F A SSS+
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 467 AAAAVGP----TVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRS--------PPVRLGSL 514
++++ P L ++ P +LS Q + SL PP G
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG-- 449
Query: 515 ERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFS 574
RL A GP P S A PP+ Q+
Sbjct: 450 --------RLLANSNAHPGPFPPSTGAQSTAH-------------PPVSTHHHHHQQQQQ 488
Query: 575 PIQEAQQDR---------------GA---PLDEGTCCSHSLPPMPLGPGMDLLGPDPSPP 616
Q+ QQ + GA PL+ G+ SH P + P + L P P P
Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGS--SHHAHPYAMSPSLGSLRPYPPGP 546
Query: 617 WSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTE 676
+ +PP P +Q+ A P P S + + + + G
Sbjct: 547 -----------AHLPP---------PHSQV-SYSQAGPNGPPVSSSSNSSSSTSQGSYPC 585
Query: 677 SRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRT--QQPAPL 734
S P S Q P P + FP + +LS + + S + +P
Sbjct: 586 SHP----SPSQGPQGAP-------YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP 634
Query: 735 AAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLG--SYSPIRSVGPFGPS 792
P P+P A+ P K GS P +P G SP P GP
Sbjct: 635 GPPPYGKRAPSPGAYKTATPP------GYKPGSPPSFRTGTPPGYRGTSP-----PAGPG 683
Query: 793 TDSSASTSCSP---PPEQPTATESLPPWSHSCPSAVRPATSQQPQKE 836
T S + P PP P+ SLPP + P++ P ++ Q ++E
Sbjct: 684 TFKPGSPTVGPGPLPPAGPSGLPSLPP-PPAAPASGPPLSATQIKQE 729
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 55.8 bits (133), Expect = 3e-07
Identities = 121/509 (23%), Positives = 163/509 (32%), Gaps = 121/509 (23%)
Query: 429 PPP--GPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSP 486
PPP P P P S P ++PE E +V+ + A PT Q P
Sbjct: 161 PPPLFPPSPQPPDSTP------RQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 487 PNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAE 546
P+ P + G +LS P +G A + G P
Sbjct: 215 PH------------------PQLYPGGTGGVLSGPPMGPKGGGAASSVGGP--------- 247
Query: 547 LAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGM 606
GG PP + SS S GAP + P P+G G
Sbjct: 248 -------NGGKQHPPPTTPISVSSSGAS---------GAPPTKP-------PTTPVGGGN 284
Query: 607 DLLGPDPSPPWSTQVCQGPHSSEM--PPAGLRATGQGPLAQLMDPGPALPGSPANSHTQR 664
P P+ PH + PP LR PL P L P H
Sbjct: 285 LPSAPPPA--------NFPHVTPNLPPPPALR-----PLNNASASPPGLGAQPLPGHLPS 331
Query: 665 D-ARARADGG---GTESRPVLRYSKEQRP---TTLPIQPFVFQHHFPKQLAKARALHSLS 717
A + GG G E P L S P ++ P P F + + A + S S
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 718 QLYSLSGCSRTQQPAPLAAPAAQVSVPAPSG------EPQASTPRATGRGARKAGSEPET 771
S S + PA A P+ S P P+ P+ + P + G P
Sbjct: 392 -----SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP-- 444
Query: 772 SRPSPLGSYSPIRSV--GPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPAT 829
P P G + GPF PST A ++ PP +H +
Sbjct: 445 --PPPYGRLLANSNAHPGPFPPST--GAQSTAHPPVS-----------THHHHHQQQQQQ 489
Query: 830 SQQPQKEDQKILTLTEYRLHGTGSLPPLGSWRSGLS-----RAESLARGGGEGSMATRPS 884
QQ Q++ Q+ + + HG PP G++ L A A GS+ P
Sbjct: 490 QQQQQQQQQQ-----QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP 544
Query: 885 NANHLSPQALKWREYRRKNPLGPPGLSGS 913
HL P + Y + P GPP S S
Sbjct: 545 GPAHLPPPHSQ-VSYSQAGPNGPPVSSSS 572
Score = 48.5 bits (114), Expect = 5e-05
Identities = 103/438 (23%), Positives = 139/438 (31%), Gaps = 81/438 (18%)
Query: 478 GQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPV-RLGSLERMLSCPVRLSEGPAAMAGPGS 536
G V T++S RQ ++ +P V + G E + + P
Sbjct: 36 GGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQE 95
Query: 537 PPR-RVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQE---FSPIQ-EAQQDRGAPLDEGT 591
PR + S + GR S P + + S +SP E D + L +G
Sbjct: 96 LPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP 155
Query: 592 CCSHSLPPMPLGPGMDLLGPDPSPPWST----QVCQGPHSSEMPPAGLRATGQGPLAQLM 647
+ PP L P P PP ST + PH S + P G A + P +++
Sbjct: 156 ARPYHPPP--------LFPPSPQPPDSTPRQPEASFEPHPS-VTPTGYHAPMEPPTSRMF 206
Query: 648 DPGPALP----------------GSPANSHTQRDARARADGGGTESRP-------VLRYS 684
P P G P A + G + P V
Sbjct: 207 QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266
Query: 685 KEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPA--AQVS 742
P T P V + P A H L P P P A S
Sbjct: 267 ASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNL----------PPPPALRPLNNASAS 316
Query: 743 VPAPSGEP---QASTPRATGRGARKAGSEPE---TSRPSPLGSYSPIRSVGPFGP----- 791
P +P +P A G+G PE T PSP S P S P P
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP-HSLPPASSSAPAPPMRFPY 375
Query: 792 -----------STDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI 840
S+ SS+S+S SP P A+++LP + HS P + S QP K Q
Sbjct: 376 SSSSSSSAAASSSSSSSSSSASPFP----ASQALPSYPHSFPPPTSLSVSNQPPKYTQPS 431
Query: 841 LTLTEYRLHGTGSLPPLG 858
L G PP G
Sbjct: 432 LPSQAVWSQGPPPPPPYG 449
Score = 42.4 bits (98), Expect = 0.003
Identities = 116/527 (22%), Positives = 169/527 (32%), Gaps = 115/527 (21%)
Query: 347 GGYGCPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSS 406
GG P A P AN P+ P PA+ L S L + L S
Sbjct: 281 GGGNLPSAPPP---ANFPHVTPNLPPPPALRPLNNASASPPGLGAQP------LPGHLPS 331
Query: 407 QSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQ 466
+ + E+ ++P P P S P+ F A SSS+
Sbjct: 332 PHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSS 391
Query: 467 AAAAVGP----TVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRS--------PPVRLGSL 514
++++ P L ++ P +LS Q + SL PP G
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG-- 449
Query: 515 ERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFS 574
RL A GP P S A PP+ Q+
Sbjct: 450 --------RLLANSNAHPGPFPPSTGAQSTAH-------------PPVSTHHHHHQQQQQ 488
Query: 575 PIQEAQQDR---------------GA---PLDEGTCCSHSLPPMPLGPGMDLLGPDPSPP 616
Q+ QQ + GA PL+ G+ SH P + P + L P P P
Sbjct: 489 QQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGS--SHHAHPYAMSPSLGSLRPYPPGP 546
Query: 617 WSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTE 676
+ +PP P +Q+ A P P S + + + + G
Sbjct: 547 -----------AHLPP---------PHSQV-SYSQAGPNGPPVSSSSNSSSSTSQGSYPC 585
Query: 677 SRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRT--QQPAPL 734
S P S Q P P + FP + +LS + + S + +P
Sbjct: 586 SHP----SPSQGPQGAP-------YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPP 634
Query: 735 AAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLG--SYSPIRSVGPFGPS 792
P P+P A+ P K GS P +P G SP P GP
Sbjct: 635 GPPPYGKRAPSPGAYKTATPP------GYKPGSPPSFRTGTPPGYRGTSP-----PAGPG 683
Query: 793 TDSSASTSCSP---PPEQPTATESLPPWSHSCPSAVRPATSQQPQKE 836
T S + P PP P+ SLPP + P++ P ++ Q ++E
Sbjct: 684 TFKPGSPTVGPGPLPPAGPSGLPSLPP-PPAAPASGPPLSATQIKQE 729
>gi|169164209 PREDICTED: hypothetical protein [Homo sapiens]
Length = 179
Score = 53.9 bits (128), Expect = 1e-06
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 734 LAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPST 793
+A +A + P+P P P R A G P +RP+P S SP R+ GPF P +
Sbjct: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60
Query: 794 DSSASTSCSPPPEQPTATESLPPWSHSCPSA 824
+S S S SPPP ++PP S P A
Sbjct: 61 HASTS-SRSPPPRARRTEPAVPPSCGSGPGA 90
>gi|239741571 PREDICTED: hypothetical protein XP_002342241 [Homo
sapiens]
Length = 179
Score = 53.9 bits (128), Expect = 1e-06
Identities = 33/91 (36%), Positives = 44/91 (48%), Gaps = 1/91 (1%)
Query: 734 LAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPST 793
+A +A + P+P P P R A G P +RP+P S SP R+ GPF P +
Sbjct: 1 MAGASAARAAPSPILPPPPDLPPTPTRRAPLIGCPPSPARPAPSASPSPSRAAGPFLPPS 60
Query: 794 DSSASTSCSPPPEQPTATESLPPWSHSCPSA 824
+S S S SPPP ++PP S P A
Sbjct: 61 HASTS-SRSPPPRARRTEPAVPPSCGSGPGA 90
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 53.9 bits (128), Expect = 1e-06
Identities = 177/789 (22%), Positives = 248/789 (31%), Gaps = 204/789 (25%)
Query: 31 GGAGGGGGSTRPNPFCPPELGITQPDQDLGQADSLLFSSLHSAPGGTARSIDSTKSRSRD 90
GG GGGG + P P+L + + G +L + GG S D +
Sbjct: 81 GGGGGGGAGSGGGPGAEPDL--KNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS 138
Query: 91 ----------------GRGPGAPKRHNPFLLQE---GVGEPGLGDLYDDSIGD----SAT 127
GR P A + + G PGL L G +
Sbjct: 139 AAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP 198
Query: 128 QQSFHLHGTGQPNFHLSSFQ-----LPP-------SGPRVGRPWGTTRSRAG-------- 167
QQ+ H HG PN +S+ PP S PR G P + AG
Sbjct: 199 QQNSHDHGF--PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS 256
Query: 168 ------------------------VVEGQEQEPVMTLDTQQCGTSHCCRPELEAETMELD 203
G +P T Q TS + D
Sbjct: 257 ASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG-D 315
Query: 204 ECGGPGGSGSGGGASDTSGFSFDQEWKLS----------------SDESPRNPGCSGSGD 247
GGP G+G G +D + Q W + S +P +PG SG G
Sbjct: 316 YSGGPQDGGAGKGPADMAS----QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGG 371
Query: 248 QHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLNSAPQSCS 307
Q + T S DQ MG + ++ Y++ G P S PQ
Sbjct: 372 Q--PLARTPQPSSPMDQ-MGKMRPQPYGGTNP--------YSQQQGPP-----SGPQQ-- 413
Query: 308 DSSFCSHSDPGAFYLDLQPSPFESKM-----------SYESHHPESGGR-EGGYG----- 350
H PG Y P + M SY P G + GYG
Sbjct: 414 -----GHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQT 468
Query: 351 --------CPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTC 402
P P S PH +P QSQ + ++Q Y
Sbjct: 469 PYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQP-----QSQPPQLQSSQPPYSQQPS 523
Query: 403 DLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVS 462
Q SP+P S S +++H + PP SQP +Q+ Q +Q A S
Sbjct: 524 QPPHQQSPAPYPSQ-QSTTQQHPQSQPP--------YSQPQAQSPYQQ---QQPQQPAPS 571
Query: 463 SSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPV 522
+ +Q AA P + Q T S ++ S+ S S P S +
Sbjct: 572 TLSQQAAYPQPQSQQSQ-QTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630
Query: 523 RLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQD 582
L P+++ P S +L G T G+ SP + S SSQ +Q
Sbjct: 631 SLQSRPSSL------PDLSGSIDDLPMG---TEGALSPGVSTSGISSSQ-------GEQS 674
Query: 583 RGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGP 642
A + H+ P +P + GP PSP S PA + + GP
Sbjct: 675 NPA---QSPFSPHTSPHLP-----GIRGPSPSPVGS-------------PASVAQSRSGP 713
Query: 643 LAQLMDPGPALPGSPANSH-------TQRDARARADGGGTESRPVL-RYSKEQRPTTL-P 693
L+ PG +P P + + + D G + P + +YS Q + L P
Sbjct: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSP 773
Query: 694 IQPFVFQHH 702
QP Q H
Sbjct: 774 RQPSGGQIH 782
Score = 40.4 bits (93), Expect = 0.013
Identities = 90/444 (20%), Positives = 143/444 (32%), Gaps = 86/444 (19%)
Query: 403 DLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVS 462
D + P P G + +++ PP GP G P + Y Q P+ P +
Sbjct: 385 DQMGKMRPQPYGGT-----NPYSQQQGPPS-GPQQGHGYPGQPYGSQTPQRYPMTMQG-- 436
Query: 463 SSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPV 522
+A +A+G G YT PP G+Q Y + Q +P S P
Sbjct: 437 ---RAQSAMG-----GLSYTQQIPPY---GQQGPSGYGQQGQ-TPYYNQQSPHPQQQQP- 483
Query: 523 RLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQD 582
P + P P S+ + + + S PP SQ+ S Q
Sbjct: 484 -----PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPY-------SQQPSQPPHQQSP 531
Query: 583 RGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGP 642
P + T H P PP+S Q P+ + P Q P
Sbjct: 532 APYPSQQSTTQQH---------------PQSQPPYSQPQAQSPYQQQQP--------QQP 568
Query: 643 LAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHH 702
+ A P P + +Q+ A YS+++ P + Q
Sbjct: 569 APSTLSQQAAYP-QPQSQQSQQTA----------------YSQQRFPPPQELS----QDS 607
Query: 703 FPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGA 762
F Q + A ++ S S +P+ L + + P G A +P + G
Sbjct: 608 FGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID-DLPMGTEGALSPGVSTSGI 666
Query: 763 RKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSAS-TSCSPPPEQPTATESLP------ 815
+ E SP ++ G GPS S S + P + ++P
Sbjct: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPP 726
Query: 816 -PWSHSCPSAVRPATSQQPQKEDQ 838
P S S + P+ +Q +D+
Sbjct: 727 RPPSGQSDSIMHPSMNQSSIAQDR 750
Score = 35.8 bits (81), Expect = 0.32
Identities = 108/494 (21%), Positives = 149/494 (30%), Gaps = 55/494 (11%)
Query: 410 PSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAA 469
PSPAGS + S G D P P+ Q P + P + S Q A
Sbjct: 1133 PSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPL-PGMSRSNSVGIQDAF 1191
Query: 470 AVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPA 529
G + + T P S R GS+ + +S G
Sbjct: 1192 NDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSMRKAPGSDPFMSSGQG 1251
Query: 530 AMAGPGSPPRRVTS--FAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPL 587
G G P R +A G ++ G P RV + P E GAP
Sbjct: 1252 PNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVR---TEPGIGP--EGNMSTGAPQ 1306
Query: 588 DEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLM 647
MP P + P PP Q Q H S G + + QG
Sbjct: 1307 PN---------LMPSNPDSGMYSPSRYPPQQQQQQQQRHDS----YGNQFSTQG-----T 1348
Query: 648 DPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQL 707
G P + Q+ + GT P R+ E P+ P+Q
Sbjct: 1349 PSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSV-----PYSTGQGQPQQ- 1402
Query: 708 AKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGS 767
QL +QQ A A P+ Q V G +T AT R+
Sbjct: 1403 ---------QQLPPAQPQPASQQQA--AQPSPQQDVYNQYGNAYPAT--ATAATERRPAG 1449
Query: 768 EPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTA--TESLPPW----SHSC 821
P+ P G R P G + + P Q +A + W +
Sbjct: 1450 GPQNQFPFQFGR---DRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTY 1506
Query: 822 PSAVRPATSQQPQKEDQKILTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMAT 881
A R +T PQ + T+ LH GSW S +R M T
Sbjct: 1507 NYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPM-T 1565
Query: 882 RPSNANHLSPQALK 895
RP +N+ P +++
Sbjct: 1566 RPPPSNYQPPPSMQ 1579
Score = 33.5 bits (75), Expect = 1.6
Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 13/127 (10%)
Query: 735 AAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTD 794
AA AA + A G Q S G+ G +P P P SP+ +G P
Sbjct: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQP---SSPMDQMGKMRPQPY 395
Query: 795 SSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKILTLTEYRLHG---T 851
+ P Q S P H P +P SQ PQ+ + + + G T
Sbjct: 396 GGTN-----PYSQQQGPPSGPQQGHGYPG--QPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448
Query: 852 GSLPPLG 858
+PP G
Sbjct: 449 QQIPPYG 455
Score = 31.2 bits (69), Expect = 8.0
Identities = 41/162 (25%), Positives = 59/162 (36%), Gaps = 28/162 (17%)
Query: 1239 EEEEEEEETEEVAEAAGGSGRARWARGGQAGWWYQLMQSSQVYIDGSIE--GSRFPRGSS 1296
+++ EE E A AA G + A G Q S+ G + G G+
Sbjct: 29 QQQREEAGGEAAAAAAAERGEMKAAAG----------QESEGPAVGPPQPLGKELQDGAE 78
Query: 1297 NSSSEKKKGAGGGGPPQAPPPREGVVEGAEACPA-----SEEALGRERGWPFWMGSPPDS 1351
++ GAG GG P A P + A PA +E G G +G+PP S
Sbjct: 79 SNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS 138
Query: 1352 VLAEL-----------RRSREREGPAASPAENEEGASEPSPG 1382
A L RS AA+ +++ + SPG
Sbjct: 139 AAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 53.9 bits (128), Expect = 1e-06
Identities = 177/789 (22%), Positives = 248/789 (31%), Gaps = 204/789 (25%)
Query: 31 GGAGGGGGSTRPNPFCPPELGITQPDQDLGQADSLLFSSLHSAPGGTARSIDSTKSRSRD 90
GG GGGG + P P+L + + G +L + GG S D +
Sbjct: 81 GGGGGGGAGSGGGPGAEPDL--KNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS 138
Query: 91 ----------------GRGPGAPKRHNPFLLQE---GVGEPGLGDLYDDSIGD----SAT 127
GR P A + + G PGL L G +
Sbjct: 139 AAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGP 198
Query: 128 QQSFHLHGTGQPNFHLSSFQ-----LPP-------SGPRVGRPWGTTRSRAG-------- 167
QQ+ H HG PN +S+ PP S PR G P + AG
Sbjct: 199 QQNSHDHGF--PNHQYNSYYPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSS 256
Query: 168 ------------------------VVEGQEQEPVMTLDTQQCGTSHCCRPELEAETMELD 203
G +P T Q TS + D
Sbjct: 257 ASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGG-D 315
Query: 204 ECGGPGGSGSGGGASDTSGFSFDQEWKLS----------------SDESPRNPGCSGSGD 247
GGP G+G G +D + Q W + S +P +PG SG G
Sbjct: 316 YSGGPQDGGAGKGPADMAS----QCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGG 371
Query: 248 QHCRCSSTSSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLNSAPQSCS 307
Q + T S DQ MG + ++ Y++ G P S PQ
Sbjct: 372 Q--PLARTPQPSSPMDQ-MGKMRPQPYGGTNP--------YSQQQGPP-----SGPQQ-- 413
Query: 308 DSSFCSHSDPGAFYLDLQPSPFESKM-----------SYESHHPESGGR-EGGYG----- 350
H PG Y P + M SY P G + GYG
Sbjct: 414 -----GHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQT 468
Query: 351 --------CPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTC 402
P P S PH +P QSQ + ++Q Y
Sbjct: 469 PYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQP-----QSQPPQLQSSQPPYSQQPS 523
Query: 403 DLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVS 462
Q SP+P S S +++H + PP SQP +Q+ Q +Q A S
Sbjct: 524 QPPHQQSPAPYPSQ-QSTTQQHPQSQPP--------YSQPQAQSPYQQ---QQPQQPAPS 571
Query: 463 SSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPV 522
+ +Q AA P + Q T S ++ S+ S S P S +
Sbjct: 572 TLSQQAAYPQPQSQQSQ-QTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNL 630
Query: 523 RLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQD 582
L P+++ P S +L G T G+ SP + S SSQ +Q
Sbjct: 631 SLQSRPSSL------PDLSGSIDDLPMG---TEGALSPGVSTSGISSSQ-------GEQS 674
Query: 583 RGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGP 642
A + H+ P +P + GP PSP S PA + + GP
Sbjct: 675 NPA---QSPFSPHTSPHLP-----GIRGPSPSPVGS-------------PASVAQSRSGP 713
Query: 643 LAQLMDPGPALPGSPANSH-------TQRDARARADGGGTESRPVL-RYSKEQRPTTL-P 693
L+ PG +P P + + + D G + P + +YS Q + L P
Sbjct: 714 LSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQYSSPQPGSALSP 773
Query: 694 IQPFVFQHH 702
QP Q H
Sbjct: 774 RQPSGGQIH 782
Score = 40.4 bits (93), Expect = 0.013
Identities = 90/444 (20%), Positives = 143/444 (32%), Gaps = 86/444 (19%)
Query: 403 DLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVS 462
D + P P G + +++ PP GP G P + Y Q P+ P +
Sbjct: 385 DQMGKMRPQPYGGT-----NPYSQQQGPPS-GPQQGHGYPGQPYGSQTPQRYPMTMQG-- 436
Query: 463 SSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPV 522
+A +A+G G YT PP G+Q Y + Q +P S P
Sbjct: 437 ---RAQSAMG-----GLSYTQQIPPY---GQQGPSGYGQQGQ-TPYYNQQSPHPQQQQP- 483
Query: 523 RLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQD 582
P + P P S+ + + + S PP SQ+ S Q
Sbjct: 484 -----PYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPY-------SQQPSQPPHQQSP 531
Query: 583 RGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGP 642
P + T H P PP+S Q P+ + P Q P
Sbjct: 532 APYPSQQSTTQQH---------------PQSQPPYSQPQAQSPYQQQQP--------QQP 568
Query: 643 LAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHH 702
+ A P P + +Q+ A YS+++ P + Q
Sbjct: 569 APSTLSQQAAYP-QPQSQQSQQTA----------------YSQQRFPPPQELS----QDS 607
Query: 703 FPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGA 762
F Q + A ++ S S +P+ L + + P G A +P + G
Sbjct: 608 FGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID-DLPMGTEGALSPGVSTSGI 666
Query: 763 RKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSAS-TSCSPPPEQPTATESLP------ 815
+ E SP ++ G GPS S S + P + ++P
Sbjct: 667 SSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGNQMPP 726
Query: 816 -PWSHSCPSAVRPATSQQPQKEDQ 838
P S S + P+ +Q +D+
Sbjct: 727 RPPSGQSDSIMHPSMNQSSIAQDR 750
Score = 33.5 bits (75), Expect = 1.6
Identities = 33/127 (25%), Positives = 45/127 (35%), Gaps = 13/127 (10%)
Query: 735 AAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTD 794
AA AA + A G Q S G+ G +P P P SP+ +G P
Sbjct: 339 AAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQP---SSPMDQMGKMRPQPY 395
Query: 795 SSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKILTLTEYRLHG---T 851
+ P Q S P H P +P SQ PQ+ + + + G T
Sbjct: 396 GGTN-----PYSQQQGPPSGPQQGHGYPG--QPYGSQTPQRYPMTMQGRAQSAMGGLSYT 448
Query: 852 GSLPPLG 858
+PP G
Sbjct: 449 QQIPPYG 455
Score = 31.2 bits (69), Expect = 8.0
Identities = 41/162 (25%), Positives = 59/162 (36%), Gaps = 28/162 (17%)
Query: 1239 EEEEEEEETEEVAEAAGGSGRARWARGGQAGWWYQLMQSSQVYIDGSIE--GSRFPRGSS 1296
+++ EE E A AA G + A G Q S+ G + G G+
Sbjct: 29 QQQREEAGGEAAAAAAAERGEMKAAAG----------QESEGPAVGPPQPLGKELQDGAE 78
Query: 1297 NSSSEKKKGAGGGGPPQAPPPREGVVEGAEACPA-----SEEALGRERGWPFWMGSPPDS 1351
++ GAG GG P A P + A PA +E G G +G+PP S
Sbjct: 79 SNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHS 138
Query: 1352 VLAEL-----------RRSREREGPAASPAENEEGASEPSPG 1382
A L RS AA+ +++ + SPG
Sbjct: 139 AAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPG 180
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 52.4 bits (124), Expect = 3e-06
Identities = 116/503 (23%), Positives = 172/503 (34%), Gaps = 102/503 (20%)
Query: 408 SSPSPAGSSITSCSEEHTKISPP---PG-----PGPDPGPSQPSEYY--LFQKPEVQPEE 457
S PSP+ I ++ T PP PG PGP P+QPS L Q+P
Sbjct: 297 SLPSPSKPPI----QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 458 QEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERM 517
+ ++ A +GP PP TG ++ S Q P +
Sbjct: 353 VQPPGTTKPPAQPLGPA----------KPPAQQTGSEKPSSE----QPGP--------KA 390
Query: 518 LSCPVRLSEGPAAMAGPGSPP-RRVTSFAELAKGRKKTGGSGSP-PLRVSVGDSSQEFSP 575
L+ P + + PA GP PP ++V + LA+ + +P P + V P
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP 450
Query: 576 IQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPW----STQVCQGPHSSEMP 631
Q+A + + G S P P P GP PP + Q P S++ P
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 632 P---AGLRATGQGPLAQL---MDPGPALPG----SPANSHTQRDAR--ARADGGGTESRP 679
P + + Q P + PG A P SPA Q+ + ++ G P
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Query: 680 VLRYSKEQRPTT-LP--IQPFV----FQHHFPKQLAKARALHSLSQLYSLSG-------- 724
+ S +Q P+ LP I P H P++ + + SL G
Sbjct: 571 TVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLT 630
Query: 725 ------CSRTQQPAPLAAPAAQV-SVPAP----------------SGEPQASTPRATGRG 761
C Q L A V S P P S +PQ ++P+
Sbjct: 631 EVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAP 690
Query: 762 ARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSC 821
+ PE +P PL P+ S S PPE + ++ PP S
Sbjct: 691 KQDLSKAPEPKKPPPLVKQ----------PTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740
Query: 822 PSAVRPATSQQPQKEDQKILTLT 844
PS A + + K++ T
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPT 763
Score = 48.5 bits (114), Expect = 5e-05
Identities = 127/532 (23%), Positives = 191/532 (35%), Gaps = 105/532 (19%)
Query: 372 PCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPP 431
P ADL+ + + R + A + + L S P A S + ++ S PP
Sbjct: 38 PAGMEADLSQLSEEERRQIAAVMSRAQ----GLPKGSVPPAAAESPSMHRKQELDSSHPP 93
Query: 432 ---GPGPDPG-PSQP------------SEYYL-----------FQKPEVQPEEQEAVSSS 464
G PDPG P+QP SE L K +E+ S
Sbjct: 94 KQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMM 153
Query: 465 TQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRL 524
+ V V +P +L + + S+ Q+ G E ++ P++
Sbjct: 154 PGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQ- 212
Query: 525 SEGPAAMA---GPGSPPR------RVTSFAELAKGRKKTGGSGSP---PLRVSVGDSSQE 572
+ P + GPG P + S + K + + G+G P P + D ++
Sbjct: 213 QQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK- 271
Query: 573 FSPIQE---AQQDRGAPLDEGTCCSHSLP--------------PMPLGPGMDLLGPDPSP 615
P+Q Q + A + G SLP P PG + P P+
Sbjct: 272 -LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK 330
Query: 616 P------WSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALP-----GSPANSHTQR 664
P + + Q P + + PP T + P L GPA P GS S Q
Sbjct: 331 PPAQPSGLTKPLAQQPGTVK-PPVQPPGTTKPPAQPL---GPAKPPAQQTGSEKPSSEQP 386
Query: 665 DARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSG 724
+A A G P Q+P P +P Q PK LA+ L S ++ G
Sbjct: 387 GPKALAQPPGVGKTPA------QQPG--PAKPPTQQVGTPKPLAQQPGLQSPAKA---PG 435
Query: 725 CSRT--QQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAG-SEPETSRPSPLGSYS 781
++T QQP P PA Q A G+ A T ++ G ++P +P P +
Sbjct: 436 PTKTPVQQPGPGKIPAQQ----AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP--AKP 489
Query: 782 PIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQP 833
P + G P + ST PPP+QP + P P + +P SQQP
Sbjct: 490 PPQQPGSAKPPSQQPGSTK--PPPQQPGPAKPSP----QQPGSTKP-PSQQP 534
Score = 46.6 bits (109), Expect = 2e-04
Identities = 87/411 (21%), Positives = 130/411 (31%), Gaps = 85/411 (20%)
Query: 416 SITSCSEEHTKISPPPGPGPDPGPSQPSEY----YLFQKPEVQPEEQEA--VSSSTQAAA 469
SI+S E K PP P GP+Q + Q+ +P+ ++A V + +
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 470 AVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSC--------- 520
P+ Q T PP G ++S+ PP + L + L+
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK----PPAQPSGLTKPLAQQPGTVKPPV 353
Query: 521 -PVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDS-SQEFSPIQE 578
P ++ PA GP PP + T + + + PP VG + +Q+ P +
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP---GVGKTPAQQPGPAKP 410
Query: 579 AQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRAT 638
Q G P P+ PG+ P P + GP AG T
Sbjct: 411 PTQQVGTP-----------KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 639 GQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFV 698
P LPG PA Q+ A+
Sbjct: 460 SAQQTGPTKPPSQ-LPG-PAKPPPQQPGPAKPP--------------------------- 490
Query: 699 FQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQAST--PR 756
P+Q A+ +QQP P Q PS + ST P
Sbjct: 491 -----PQQPGSAKP--------------PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 757 ATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQ 807
A+ + +P ++PS S P+ G P + S S PP Q
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
Score = 45.1 bits (105), Expect = 5e-04
Identities = 113/512 (22%), Positives = 171/512 (33%), Gaps = 100/512 (19%)
Query: 408 SSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQA 467
++ + G + + S HT I G + SQ SE Q V Q S
Sbjct: 18 AAAAAGGGASGAGSPSHTAIPA----GMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPP 73
Query: 468 AAAVGPTVLEGQVYTNTSPPNLS-----------TGRQRSRSYD--RSLQRSP---PVRL 511
AAA P++ Q ++ PP S G +SR+ D RS Q+ P P +
Sbjct: 74 AAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTI 133
Query: 512 GSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELA----------------------- 548
E ++ + M G S +++ + +
Sbjct: 134 SLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQ 193
Query: 549 ----KGRKKTGGSGSPPLRVSVGDS-SQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLG 603
K + K G PPL+ ++ P ++ Q G P + + P G
Sbjct: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253
Query: 604 PGMDLLGP---------------DPSPPWSTQ--VCQG-------PHSSEMP---PAGLR 636
G + GP D S P + Q + +G P S+ P P +
Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313
Query: 637 ATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTL--PI 694
Q P + PGPA P + + T + A GT PV + P P
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLT----KPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
Query: 695 QPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAP-SGEPQAS 753
+P Q K ++ +L+Q + G + QQP P P QV P P + +P
Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 754 TPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTS--------CSPPP 805
+P KA +T P P + GP S + T PPP
Sbjct: 429 SP-------AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481
Query: 806 EQPTATESLP--PWSHSCPSAVRPATSQQPQK 835
+QP + P P S PS +T PQ+
Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Score = 38.5 bits (88), Expect = 0.050
Identities = 70/326 (21%), Positives = 114/326 (34%), Gaps = 47/326 (14%)
Query: 410 PSPAGSSITSCSEEHTKISPPPG------PGPDPGPSQPSEYYLFQKPEVQPEEQEAVSS 463
P P T K PP P P PS PSE + +P++ + V
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762
Query: 464 STQAAAAVGPTV--------LEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPV------ 509
+T ++ T ++ Q T+PP + + S+S+ + ++ P
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 510 RLGSLERMLSCPVRLSEGPA-----AMAGPGSPPRRVTSFAELAKGRKKTGGSGSPP-LR 563
R S +++S P SE + P + T + + GS +PP R
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR 882
Query: 564 VSVGDS--SQEFSPIQEAQQDR---------GAPLDEGTCCSHSLPPMPLGPGMDLLGPD 612
+ G + + + SP + Q R AP + T ++ G G +
Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFS-Q 941
Query: 613 PSPPWSTQVCQGPHSSEMPPAGLR--------ATGQGPLAQLMDPGPALPGS-PANSHTQ 663
S ST GPHS P A ++ T QGP PA S P T+
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001
Query: 664 RDARARADGGGTESRPVLRYSKEQRP 689
A + + ++ V R E++P
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKP 1027
Score = 32.7 bits (73), Expect = 2.7
Identities = 41/172 (23%), Positives = 64/172 (37%), Gaps = 23/172 (13%)
Query: 1311 PPQAPPPREGVVE--GAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAAS 1368
P +AP P + V+ G PA + G+ PP + + ++ GPA
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
Query: 1369 PAENEEGASEPS--PGGIK-----------WGHLFGSRKAQRE----ARPTNRLPSDWLS 1411
P + A PS PG K GS K + A+P+ + PS
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP 549
Query: 1412 LDKSMFQLVAQTVGSR--REPEPKESLQEPHSPALPSS--PPCEVQALCHHL 1459
+ + V+QT + + P S ++P S LP + P C L H+
Sbjct: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601
Score = 31.6 bits (70), Expect = 6.1
Identities = 21/84 (25%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 385 SQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSE 444
S + L + +++ + D+S+Q P P PPP P P P P P
Sbjct: 2382 SVSSLPAKPRPFFRSSSLDISAQPPPPPPPP-------------PPPPPPPPPPPPPPLP 2428
Query: 445 YYLFQKPEVQPEEQEAVSSSTQAA 468
KP + P+++ V+S A
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTA 2452
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 52.4 bits (124), Expect = 3e-06
Identities = 116/503 (23%), Positives = 172/503 (34%), Gaps = 102/503 (20%)
Query: 408 SSPSPAGSSITSCSEEHTKISPP---PG-----PGPDPGPSQPSEYY--LFQKPEVQPEE 457
S PSP+ I ++ T PP PG PGP P+QPS L Q+P
Sbjct: 297 SLPSPSKPPI----QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 458 QEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERM 517
+ ++ A +GP PP TG ++ S Q P +
Sbjct: 353 VQPPGTTKPPAQPLGPA----------KPPAQQTGSEKPSSE----QPGP--------KA 390
Query: 518 LSCPVRLSEGPAAMAGPGSPP-RRVTSFAELAKGRKKTGGSGSP-PLRVSVGDSSQEFSP 575
L+ P + + PA GP PP ++V + LA+ + +P P + V P
Sbjct: 391 LAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP 450
Query: 576 IQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPW----STQVCQGPHSSEMP 631
Q+A + + G S P P P GP PP + Q P S++ P
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 632 P---AGLRATGQGPLAQL---MDPGPALPG----SPANSHTQRDAR--ARADGGGTESRP 679
P + + Q P + PG A P SPA Q+ + ++ G P
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Query: 680 VLRYSKEQRPTT-LP--IQPFV----FQHHFPKQLAKARALHSLSQLYSLSG-------- 724
+ S +Q P+ LP I P H P++ + + SL G
Sbjct: 571 TVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLT 630
Query: 725 ------CSRTQQPAPLAAPAAQV-SVPAP----------------SGEPQASTPRATGRG 761
C Q L A V S P P S +PQ ++P+
Sbjct: 631 EVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAP 690
Query: 762 ARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSC 821
+ PE +P PL P+ S S PPE + ++ PP S
Sbjct: 691 KQDLSKAPEPKKPPPLVKQ----------PTLHGSPSAKAKQPPEADSLSKPAPPKEPSV 740
Query: 822 PSAVRPATSQQPQKEDQKILTLT 844
PS A + + K++ T
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPT 763
Score = 48.5 bits (114), Expect = 5e-05
Identities = 127/532 (23%), Positives = 191/532 (35%), Gaps = 105/532 (19%)
Query: 372 PCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPP 431
P ADL+ + + R + A + + L S P A S + ++ S PP
Sbjct: 38 PAGMEADLSQLSEEERRQIAAVMSRAQ----GLPKGSVPPAAAESPSMHRKQELDSSHPP 93
Query: 432 ---GPGPDPG-PSQP------------SEYYL-----------FQKPEVQPEEQEAVSSS 464
G PDPG P+QP SE L K +E+ S
Sbjct: 94 KQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMM 153
Query: 465 TQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRL 524
+ V V +P +L + + S+ Q+ G E ++ P++
Sbjct: 154 PGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQ- 212
Query: 525 SEGPAAMA---GPGSPPR------RVTSFAELAKGRKKTGGSGSP---PLRVSVGDSSQE 572
+ P + GPG P + S + K + + G+G P P + D ++
Sbjct: 213 QQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK- 271
Query: 573 FSPIQE---AQQDRGAPLDEGTCCSHSLP--------------PMPLGPGMDLLGPDPSP 615
P+Q Q + A + G SLP P PG + P P+
Sbjct: 272 -LPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK 330
Query: 616 P------WSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALP-----GSPANSHTQR 664
P + + Q P + + PP T + P L GPA P GS S Q
Sbjct: 331 PPAQPSGLTKPLAQQPGTVK-PPVQPPGTTKPPAQPL---GPAKPPAQQTGSEKPSSEQP 386
Query: 665 DARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSG 724
+A A G P Q+P P +P Q PK LA+ L S ++ G
Sbjct: 387 GPKALAQPPGVGKTPA------QQPG--PAKPPTQQVGTPKPLAQQPGLQSPAKA---PG 435
Query: 725 CSRT--QQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAG-SEPETSRPSPLGSYS 781
++T QQP P PA Q A G+ A T ++ G ++P +P P +
Sbjct: 436 PTKTPVQQPGPGKIPAQQ----AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP--AKP 489
Query: 782 PIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQP 833
P + G P + ST PPP+QP + P P + +P SQQP
Sbjct: 490 PPQQPGSAKPPSQQPGSTK--PPPQQPGPAKPSP----QQPGSTKP-PSQQP 534
Score = 46.6 bits (109), Expect = 2e-04
Identities = 87/411 (21%), Positives = 130/411 (31%), Gaps = 85/411 (20%)
Query: 416 SITSCSEEHTKISPPPGPGPDPGPSQPSEY----YLFQKPEVQPEEQEA--VSSSTQAAA 469
SI+S E K PP P GP+Q + Q+ +P+ ++A V + +
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 470 AVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSC--------- 520
P+ Q T PP G ++S+ PP + L + L+
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAK----PPAQPSGLTKPLAQQPGTVKPPV 353
Query: 521 -PVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDS-SQEFSPIQE 578
P ++ PA GP PP + T + + + PP VG + +Q+ P +
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP---GVGKTPAQQPGPAKP 410
Query: 579 AQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRAT 638
Q G P P+ PG+ P P + GP AG T
Sbjct: 411 PTQQVGTP-----------KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKT 459
Query: 639 GQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFV 698
P LPG PA Q+ A+
Sbjct: 460 SAQQTGPTKPPSQ-LPG-PAKPPPQQPGPAKPP--------------------------- 490
Query: 699 FQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQAST--PR 756
P+Q A+ +QQP P Q PS + ST P
Sbjct: 491 -----PQQPGSAKP--------------PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 757 ATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQ 807
A+ + +P ++PS S P+ G P + S S PP Q
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ 582
Score = 45.1 bits (105), Expect = 5e-04
Identities = 113/512 (22%), Positives = 171/512 (33%), Gaps = 100/512 (19%)
Query: 408 SSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQA 467
++ + G + + S HT I G + SQ SE Q V Q S
Sbjct: 18 AAAAAGGGASGAGSPSHTAIPA----GMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPP 73
Query: 468 AAAVGPTVLEGQVYTNTSPPNLS-----------TGRQRSRSYD--RSLQRSP---PVRL 511
AAA P++ Q ++ PP S G +SR+ D RS Q+ P P +
Sbjct: 74 AAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTI 133
Query: 512 GSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELA----------------------- 548
E ++ + M G S +++ + +
Sbjct: 134 SLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQ 193
Query: 549 ----KGRKKTGGSGSPPLRVSVGDS-SQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLG 603
K + K G PPL+ ++ P ++ Q G P + + P G
Sbjct: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253
Query: 604 PGMDLLGP---------------DPSPPWSTQ--VCQG-------PHSSEMP---PAGLR 636
G + GP D S P + Q + +G P S+ P P +
Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313
Query: 637 ATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTL--PI 694
Q P + PGPA P + + T + A GT PV + P P
Sbjct: 314 PPAQQPGHEKSQPGPAKPPAQPSGLT----KPLAQQPGTVKPPVQPPGTTKPPAQPLGPA 369
Query: 695 QPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAP-SGEPQAS 753
+P Q K ++ +L+Q + G + QQP P P QV P P + +P
Sbjct: 370 KPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQ 428
Query: 754 TPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTS--------CSPPP 805
+P KA +T P P + GP S + T PPP
Sbjct: 429 SP-------AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP 481
Query: 806 EQPTATESLP--PWSHSCPSAVRPATSQQPQK 835
+QP + P P S PS +T PQ+
Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Score = 38.5 bits (88), Expect = 0.050
Identities = 70/326 (21%), Positives = 114/326 (34%), Gaps = 47/326 (14%)
Query: 410 PSPAGSSITSCSEEHTKISPPPG------PGPDPGPSQPSEYYLFQKPEVQPEEQEAVSS 463
P P T K PP P P PS PSE + +P++ + V
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762
Query: 464 STQAAAAVGPTV--------LEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPV------ 509
+T ++ T ++ Q T+PP + + S+S+ + ++ P
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 510 RLGSLERMLSCPVRLSEGPA-----AMAGPGSPPRRVTSFAELAKGRKKTGGSGSPP-LR 563
R S +++S P SE + P + T + + GS +PP R
Sbjct: 823 RPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR 882
Query: 564 VSVGDS--SQEFSPIQEAQQDR---------GAPLDEGTCCSHSLPPMPLGPGMDLLGPD 612
+ G + + + SP + Q R AP + T ++ G G +
Sbjct: 883 PTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFS-Q 941
Query: 613 PSPPWSTQVCQGPHSSEMPPAGLR--------ATGQGPLAQLMDPGPALPGS-PANSHTQ 663
S ST GPHS P A ++ T QGP PA S P T+
Sbjct: 942 ASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001
Query: 664 RDARARADGGGTESRPVLRYSKEQRP 689
A + + ++ V R E++P
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKP 1027
Score = 32.7 bits (73), Expect = 2.7
Identities = 41/172 (23%), Positives = 64/172 (37%), Gaps = 23/172 (13%)
Query: 1311 PPQAPPPREGVVE--GAEACPASEEALGRERGWPFWMGSPPDSVLAELRRSREREGPAAS 1368
P +AP P + V+ G PA + G+ PP + + ++ GPA
Sbjct: 430 PAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKP 489
Query: 1369 PAENEEGASEPS--PGGIK-----------WGHLFGSRKAQRE----ARPTNRLPSDWLS 1411
P + A PS PG K GS K + A+P+ + PS
Sbjct: 490 PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKP 549
Query: 1412 LDKSMFQLVAQTVGSR--REPEPKESLQEPHSPALPSS--PPCEVQALCHHL 1459
+ + V+QT + + P S ++P S LP + P C L H+
Sbjct: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601
Score = 31.6 bits (70), Expect = 6.1
Identities = 21/84 (25%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 385 SQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSE 444
S + L + +++ + D+S+Q P P PPP P P P P P
Sbjct: 2382 SVSSLPAKPRPFFRSSSLDISAQPPPPPPPP-------------PPPPPPPPPPPPPPLP 2428
Query: 445 YYLFQKPEVQPEEQEAVSSSTQAA 468
KP + P+++ V+S A
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTA 2452
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 52.4 bits (124), Expect = 3e-06
Identities = 118/486 (24%), Positives = 174/486 (35%), Gaps = 64/486 (13%)
Query: 457 EQEAVSSSTQAAAAVGPTVLE--GQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSL 514
++++ SS +++ + P +E G + + R+ S +RS S P L
Sbjct: 1372 KEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGL 1431
Query: 515 ERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFS 574
R S R P G G+P R S + + G P S G S + S
Sbjct: 1432 PRTPSRRSRSGSSPGLRDGSGTPSRHSLSGS--------SPGMKDIPRTPSRGRSECDSS 1483
Query: 575 PIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAG 634
P +A P S L L P + G + S T P G
Sbjct: 1484 PEPKALPQTPRPRSRSPS-SPELNNKCLTPQRERSGSESSVDQKTVA--------RTPLG 1534
Query: 635 LRATGQGPLAQLMDPGP-ALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLP 693
R+ +Q +D P A P + S + D++A+ T P
Sbjct: 1535 QRSRSGS--SQELDVKPSASPQERSESDSSPDSKAK--------------------TRTP 1572
Query: 694 IQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQAS 753
++ P+ +K+R LS S SG S + P AAP AQ S S EP+A
Sbjct: 1573 LRQRSRSGSSPEVDSKSR----LSPRRSRSGSSPEVKDKPRAAPRAQ-SGSDSSPEPKAP 1627
Query: 754 TPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATES 813
PRA R +R +GS + PSP GS S S S + + SP P+ + T
Sbjct: 1628 APRALPRRSR-SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP 1686
Query: 814 LPPWSHSCPSAVRPATSQQPQKE-----DQKILTLTEYRLHGTGSLP-PLGSWRS----- 862
S S P R A + + + + T +R + S P P RS
Sbjct: 1687 RRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRR 1746
Query: 863 --GLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYRRKNPLGPPGLSGSLDRRSQE 920
R ++ +R G S R + + K R RR++ G S S RR Q
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD---RSGSSQSTSRRRQR 1803
Query: 921 ARLARR 926
+R R
Sbjct: 1804 SRSRSR 1809
Score = 50.1 bits (118), Expect = 2e-05
Identities = 78/349 (22%), Positives = 129/349 (36%), Gaps = 33/349 (9%)
Query: 352 PHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPS 411
P SS A S P + P + + + F Q+R ++A T SQS S
Sbjct: 2425 PSPSSRMGQAPSQSLLPPAQDQPR-SPVPSAFSDQSRCLIAQ------TTPVAGSQSLSS 2477
Query: 412 PAGSSITSCSEEHTKISPPPGPG-PDPGPSQPSEYYLFQKPE----VQPEEQEAVSSSTQ 466
A ++ TS + +H + P PG P +P Q+P +QP ++ SSS+
Sbjct: 2478 GAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537
Query: 467 AAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSE 526
++++ +++S + S+G S S SL P V +L+R+ S +
Sbjct: 2538 SSSS------SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEV---ALKRVPS----PTP 2584
Query: 527 GPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAP 586
P G PP AK ++++ S S S SS S + +
Sbjct: 2585 APKEAVREGRPPEPTP-----AKRKRRSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSS 2636
Query: 587 LDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQL 646
+ S S P P PG L SP + S P LR + + +
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPV 2696
Query: 647 MDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQ 695
P+ SP + + R G +SR + + P+ P++
Sbjct: 2697 ERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR 2745
Score = 45.4 bits (106), Expect = 4e-04
Identities = 55/211 (26%), Positives = 87/211 (41%), Gaps = 33/211 (15%)
Query: 720 YSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRAT--GRGARKAGSEPETSRPSPL 777
+S G + TQ+P+ Q S P + AT ++ + PE P+PL
Sbjct: 310 FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPL 369
Query: 778 ------GSYSPIR----SVGPFGPSTDSSASTSCSPP--PE---QPTATESLPP------ 816
GS P+ S P P +++S + SPP PE Q +++ES PP
Sbjct: 370 LAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTK 429
Query: 817 ---WSHSCPSAVRPATSQQPQKEDQKILTLTEYRLHGTG----SLPPLGSWRSGLSRAES 869
+ S P + +PA + +E T ++ R HG S S R G SR+ +
Sbjct: 430 VSRHASSSPESPKPAPAPGSHREISSSPT-SKNRSHGRAKRDKSHSHTPSRRMGRSRSPA 488
Query: 870 LARGGGEGSMATRPSNANHLSPQALKWREYR 900
A+ G S + P+ H ++ +WR R
Sbjct: 489 TAKRG--RSRSRTPTKRGHSRSRSPQWRRSR 517
Score = 42.7 bits (99), Expect = 0.003
Identities = 104/469 (22%), Positives = 163/469 (34%), Gaps = 91/469 (19%)
Query: 409 SPSPAGSSITSCSEEHTKISPPPGPGPDPG-PSQPSEYYLFQKPEVQPEEQEAVSSSTQA 467
S +PA ++ + + T ++P DP P+ P+ + T A
Sbjct: 2259 SRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAV--------------NLAGARTPA 2304
Query: 468 AAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYD----RSLQRSPPVRL-GSLERMLSCPV 522
A A G T + P+ S Q S + RS + PV + GS P
Sbjct: 2305 ALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPA 2364
Query: 523 RLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQD 582
L+ A A G+ +TS ++ G SPPL + +P Q
Sbjct: 2365 SLTSARMAPALSGA---NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTS 2421
Query: 583 RGAPLDE---GTCCSHSLPPMPLGPGMDL-LGPDPSPPWSTQVCQGPHSSEMPPAGLRAT 638
AP G S SL P P D P PS C ++ P AG ++
Sbjct: 2422 ERAPSPSSRMGQAPSQSLLP----PAQDQPRSPVPSAFSDQSRCLIAQTT--PVAGSQSL 2475
Query: 639 GQGPLA-----------QLMDPGPALPGS-----PANSHTQRDARARADGGGTESRPVLR 682
G +A L P P +P S PA++ Q+ + A L+
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA----------LQ 2525
Query: 683 YSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPA---PLAAPAA 739
+KE+R ++ + + + S S S SG S + P+ A
Sbjct: 2526 PAKERRSSSSS----------SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA 2575
Query: 740 QVSVPAPS---------GEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFG 790
VP+P+ G P TP R + + S +S S S S S
Sbjct: 2576 LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635
Query: 791 PSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQK 839
S+ SS+S+S S P ++LP +PA+ ++P +++
Sbjct: 2636 SSSSSSSSSSSSSPSPAKPGPQALP----------KPASPKKPPPGERR 2674
Score = 42.0 bits (97), Expect = 0.005
Identities = 105/422 (24%), Positives = 139/422 (32%), Gaps = 75/422 (17%)
Query: 406 SQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPS-EYYLFQKPEVQPEEQEAVSSS 464
S SSP P S T + H+ SP P P Q S + V P+ + SS
Sbjct: 817 SSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
Query: 465 TQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRL 524
+ + +SPP + + +S RS P V+ R S
Sbjct: 877 PD--PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSS 934
Query: 525 SEGPAAMAGPGSPPRRVTSFAELAK------GRKKTGGSGSPPLRVSV-----GDSSQEF 573
S P+ + + PRR S + + R GS SP +V S
Sbjct: 935 SPSPSRVTS-RTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSI 993
Query: 574 SPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPA 633
SP + + A G S S P P D L S P S +C G SS P
Sbjct: 994 SPYPKVK----AQTPPGPSLSGSKSPCPQEKSKDSL--VQSCPGSLSLCAGVKSS--TPP 1045
Query: 634 GLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLP 693
G G L QL S T D R+ S P +R S + P
Sbjct: 1046 GESYFGVSSL-QL----------KGQSQTSPDHRS------DTSSPEVRQSHSESP---- 1084
Query: 694 IQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQAS 753
+L S SQ G SR+ +P+ A++ + GE AS
Sbjct: 1085 ------------------SLQSKSQTSPKGGRSRSS--SPVTELASRSPIRQDRGEFSAS 1124
Query: 754 TPRATGRGARKAGSEPETSR-PSPLGSYSPIRSVGPFGPS---TDSSASTSCSPPPEQPT 809
K+G PE SR S SY + S G S T S PP E T
Sbjct: 1125 P-------MLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDAT 1177
Query: 810 AT 811
A+
Sbjct: 1178 AS 1179
Score = 35.4 bits (80), Expect = 0.42
Identities = 40/184 (21%), Positives = 68/184 (36%), Gaps = 18/184 (9%)
Query: 300 NSAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYESHHPESGGREGGYGCPHASSPEL 359
+S+ S S SS S SD L +QP ++ + P+ REG PE
Sbjct: 2546 SSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREG-------RPPEP 2598
Query: 360 DANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITS 419
R + + ++ S + ++ + + SS SSPSPA +
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658
Query: 420 CSEEHTKISPPPGPGPDPGPSQPSEYYL-----------FQKPEVQPEEQEAVSSSTQAA 468
+ + PPPG P +P + ++P QP ++ SSS++
Sbjct: 2659 LPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERG 2718
Query: 469 AAVG 472
+ G
Sbjct: 2719 SRRG 2722
Score = 33.9 bits (76), Expect = 1.2
Identities = 59/247 (23%), Positives = 87/247 (35%), Gaps = 28/247 (11%)
Query: 322 LDLQPSPFESKMSYESHHPESGGREGG---YGCPHASSPELDANC--NSYRPHCEPCPAV 376
LD++PS + S P+S + SSPE+D+ + R P V
Sbjct: 1545 LDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV 1604
Query: 377 ADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPD 436
D + R Q+ S SSP P + + S G GP
Sbjct: 1605 KD-------KPRAAPRAQS---------GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPS 1648
Query: 437 PGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRS 496
P S +E PE P+ + A S + + + ++ S P L+ + S
Sbjct: 1649 PEGSSSTE----SSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLS 1704
Query: 497 RSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGG 556
R RS SP R + R P S PA + S RR ++ + K + G
Sbjct: 1705 RR-SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKS--RSSRRRRSASSPRTKTTSRRGR 1761
Query: 557 SGSPPLR 563
S SP R
Sbjct: 1762 SPSPKPR 1768
Score = 32.3 bits (72), Expect = 3.6
Identities = 44/194 (22%), Positives = 74/194 (38%), Gaps = 30/194 (15%)
Query: 350 GCPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSS 409
G PH+ E A+ + +P A+A L + R ++ + + SS SS
Sbjct: 2500 GVPHSDVGEPPASTGAQQPS-----ALAALQPA--KERRSSSSSSSSSSSSSSSSSSSSS 2552
Query: 410 PSPAGSSITSCSEEHTKISPPPG----PGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSST 465
S +GSS + + P P P P P + + PE P +++ SSS+
Sbjct: 2553 SSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE--GRPPEPTPAKRKRRSSSS 2610
Query: 466 QAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLS 525
++++ +++S + S+ S S S S S S P
Sbjct: 2611 SSSSS-----------SSSSSSSSSSSSSSSSSSSSSSSSS------SSSSSSSSPSPAK 2653
Query: 526 EGPAAMAGPGSPPR 539
GP A+ P SP +
Sbjct: 2654 PGPQALPKPASPKK 2667
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 51.6 bits (122), Expect = 6e-06
Identities = 101/435 (23%), Positives = 144/435 (33%), Gaps = 57/435 (13%)
Query: 408 SSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYY-LFQKPEVQPEEQEAVSSSTQ 466
+SP P S ++ EE + +SPPP P P + S + F++ + P +E+ S
Sbjct: 563 TSPPPEASRLSPPPEE-SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621
Query: 467 AAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSE 526
A+ + P + + SPP + S + R P L + R+ P
Sbjct: 622 EASRLSPPPEDSPM----SPP----PEESPMSPPPEVSRLSP--LPVVSRLSPPPEESPL 671
Query: 527 GPAAMAGPGSPPRRVTSFA----ELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQE-AQQ 581
P P SPP + + + SPP S+ E SP+ ++
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEE 731
Query: 582 DRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAG-LRATGQ 640
+ P EG L P P P L P P P + + PH S P L A +
Sbjct: 732 PQLCPRSEGP----HLSPRPEEPH---LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPE 784
Query: 641 GPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLP-----IQ 695
P GP L P H P L E+ + +
Sbjct: 785 EPHLSPQAEGPHLSPQPEELHLSPQTE-EPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843
Query: 696 PFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTP 755
P + H +L K + G + PL P + S+ GEP S P
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP 903
Query: 756 RATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLP 815
EP PL SP+ P PS + S S PP P P
Sbjct: 904 -----------GEP------PL---SPLPEELPLSPSGEPSLSPQLMPPDPLP------P 937
Query: 816 PWSHSCPSAVRPATS 830
P S +A PA S
Sbjct: 938 PLSPIITAAAPPALS 952
Score = 47.0 bits (110), Expect = 1e-04
Identities = 101/413 (24%), Positives = 140/413 (33%), Gaps = 67/413 (16%)
Query: 451 PEVQPEEQEAVSSSTQAA--------AAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRS 502
P+ Q ++Q A+ A A+GPT+L NT P +S+
Sbjct: 3987 PQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSS----------E 4036
Query: 503 LQRSPPVRLGSLERMLSCPVRLSEGPAAMAG-PGSPPRRVTSFAELAKGRKKTGGSGS-- 559
P G P+ + P +MA PG ++ ++L + + S
Sbjct: 4037 ATEGPSTHQGG-------PLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSL 4089
Query: 560 ---PPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPP 616
PPLR+ G Q+ S + A L G+ S P L LG P
Sbjct: 4090 QLQPPLRLP-GQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGS- 4147
Query: 617 WSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALP---GSPANSHTQRDARARADGG 673
TQ GP + TG P PGP L G P + RA
Sbjct: 4148 -MTQNLLGPQQPMLERPMQNNTGPQP----PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQ 4202
Query: 674 GTESR-PVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSL----------SQLYSL 722
G ++ P LR+ Q+ L Q + Q +QL +++A+ S L L
Sbjct: 4203 GVLAKNPQLRHLSPQQQQQL--QALLMQ----RQLQQSQAVRQTPPYQEPGTQTSPLQGL 4256
Query: 723 SGCSRTQQ--PAPLAAPAAQVSV-PAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGS 779
GC P P P ++ P P G P+ P GA G P+P S
Sbjct: 4257 LGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPP----GALSTGPVLGPVHPTPPPS 4312
Query: 780 YSPIRSVGPFG-PSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQ 831
SP P PS S T PP P + P P V PA +Q
Sbjct: 4313 -SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQ 4364
Score = 46.2 bits (108), Expect = 2e-04
Identities = 135/578 (23%), Positives = 181/578 (31%), Gaps = 48/578 (8%)
Query: 423 EHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYT 482
E + +SPPP P P + S L PE P + P +
Sbjct: 445 EESPLSPPPEESPTSPPPEASR--LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESP 502
Query: 483 NTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSE-GPAAMAGPGSPPRRV 541
+ PP S S + SPP +LE LS P S P P SPP
Sbjct: 503 LSPPPESSPFSPLEESPLSPPEESPP--SPALETPLSPPPEASPLSPPFEESPLSPPPE- 559
Query: 542 TSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQ-EAQQDRGAPLDEGTCCSHSLPPM 600
EL SPP S E SP+ + R P E + S
Sbjct: 560 ----ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615
Query: 601 PLGPGMDLLGPDPSPPWSTQVCQGPHSSEM-PPAGLRATGQGPLAQLMDPGP---ALPGS 656
PL P + P PP + + P S M PP + P+ + P P L
Sbjct: 616 PLSPPPEASRLSP-PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPP 674
Query: 657 PANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSL 716
P S T A E P E P + P + + P + + L
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPT-SPPPEDSPASPPPEDSLMS--LPLEESPLLPLPEE 731
Query: 717 SQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSG---EPQASTPRATGRGAR----KAGSEP 769
QL C R++ P P P P PQA P + + EP
Sbjct: 732 PQL-----CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786
Query: 770 ETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPAT 829
S + SP P T+ SP PE+P + P SH P + P
Sbjct: 787 HLSPQAEGPHLSPQPEELHLSPQTE---EPHLSPVPEEPCLSPQ-PEESHLSPQSEEPCL 842
Query: 830 SQQPQKEDQKILTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMAT---RPSNA 886
S +P+ E L + L PP + L GE S++ P+ +
Sbjct: 843 SPRPE-ESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALS 901
Query: 887 NHLSPQALKWREYRRKNPLGPPGLSGSLDRRSQEARLARRNPIF--EFPGSLSAASHLNC 944
P E +P G P LS L + +PI P +LS L
Sbjct: 902 EPGEPPLSPLPEELPLSPSGEPSLSPQL--MPPDPLPPPLSPIITAAAPPALSPLGELEY 959
Query: 945 RL--NGQAVKPLPLTCPDFQDPFSLTEKPPAEFCLSPD 980
G + PL P + P S PP C P+
Sbjct: 960 PFGAKGDSDPESPLAAPILETPIS---PPPEANCTDPE 994
Score = 44.3 bits (103), Expect = 0.001
Identities = 108/460 (23%), Positives = 157/460 (34%), Gaps = 82/460 (17%)
Query: 406 SQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSST 465
S +SP P E +++SPPP P P + S P P E +S
Sbjct: 678 SPTSPPP----------EASRLSPPPEDSPTSPPPEDS-------PASPPPEDSLMSLPL 720
Query: 466 QAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLS 525
+ + + P E Q+ + P+LS + R P + + E LS
Sbjct: 721 EESPLL-PLPEEPQLCPRSEGPHLSPRPEEPHLSPR--PEEPHLSPQAEEPHLS---PQP 774
Query: 526 EGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSP---PLRVSVGDSSQEFSPIQE---- 578
E P A P P ++ AE G SP L +S SP+ E
Sbjct: 775 EEPCLCAVPEEP--HLSPQAE--------GPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824
Query: 579 ---AQQDRGAPLDEGTCCSHSLPPMPLGPGMDL--LGPDP-SPPWSTQVCQGPHSSEM-P 631
++ +P E C S L P ++ L P P PP C P + P
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFP 884
Query: 632 PAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTT 691
P G PL L +P + PG P S + G + S ++ P
Sbjct: 885 PPG--EPSLSPL--LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM----PPDPLP 936
Query: 692 LPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQP-APLAAPAAQVSVPAPSGEP 750
P+ P + A AL L +L G P +PLAAP + + P P
Sbjct: 937 PPLSPII-------TAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPP---P 986
Query: 751 QASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTA 810
+A+ ++PE P L SP VGP P CSP +
Sbjct: 987 EANC------------TDPEPVPPMILPP-SPGSPVGPASPILMEPLPPQCSPLLQHSLV 1033
Query: 811 TESLPPWSHSCPSAVRPATSQQPQKEDQKILTLT-EYRLH 849
++ PP C P + P K++ ++ E LH
Sbjct: 1034 PQNSPP--SQCSPPALPLSVPSPLSPIGKVVGVSDEAELH 1071
Score = 36.6 bits (83), Expect = 0.19
Identities = 107/491 (21%), Positives = 155/491 (31%), Gaps = 98/491 (19%)
Query: 295 PRANLNSAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMSYE-SHHPESGGREGGYGCPH 353
P A+ S P S +S P + P P +S MS P E CP
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPAS------PPPEDSLMSLPLEESPLLPLPEEPQLCPR 737
Query: 354 ASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPA 413
+ P L PH P P L+ QA SP P
Sbjct: 738 SEGPHLSPRPEE--PHLSPRPEEPHLSP----QAE----------------EPHLSPQPE 775
Query: 414 GSSITSCSEE-HTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVG 472
+ + EE H P GP P QP E +L P+ +E S +
Sbjct: 776 EPCLCAVPEEPHLS---PQAEGPHLSP-QPEELHL------SPQTEEPHLSPVPEEPCLS 825
Query: 473 PTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMA 532
P E + + P LS + S L++ PP+ R P + PA
Sbjct: 826 PQPEESHLSPQSEEPCLSPRPEESH-LSPELEK-PPLS----PRPEKPPEEPGQCPAPEE 879
Query: 533 GPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTC 592
P PP S + L G G PPL SP+ E +P E +
Sbjct: 880 LPLFPPPGEPSLSPLL-GEPALSEPGEPPL-----------SPLPEELPL--SPSGEPSL 925
Query: 593 CSHSLPPMPLGPGMD---------LLGP--------------DPSPPWSTQVCQGPHSSE 629
+PP PL P + L P DP P + + + P S
Sbjct: 926 SPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPIS-- 983
Query: 630 MPPAGLRATGQGPLA-QLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSK-EQ 687
PP T P+ ++ P P P PA+ + P+L++S Q
Sbjct: 984 -PPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS-------PLLQHSLVPQ 1035
Query: 688 RPTTLPIQPFVFQHHFPKQLA---KARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVP 744
P P L+ K + ++L+ + ++ P P+A +P
Sbjct: 1036 NSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLP 1095
Query: 745 APSGEPQASTP 755
+P G+ P
Sbjct: 1096 SPMGDLSCPAP 1106
Score = 34.7 bits (78), Expect = 0.72
Identities = 98/410 (23%), Positives = 140/410 (34%), Gaps = 73/410 (17%)
Query: 431 PGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLS 490
P G PGP P E +L P+V + S A P T PP S
Sbjct: 2145 PPAGSVPGPDSPGELFLKLPPQV---PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPS 2201
Query: 491 -TGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAK 549
TG + P LG+ R P G PG+P + ++ K
Sbjct: 2202 PTGAP-----------AQPPMLGASSR----PGAGQPGEFHTTPPGTPRHQPSTPDPFLK 2246
Query: 550 GRKKTGGSGSPPLRVSVGDSSQEF-----SPIQEAQQDRGAPLDEGTCCSHSLPPMPLG- 603
R + + + P VG P E+++ +E S S P LG
Sbjct: 2247 PRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF 2306
Query: 604 ----------PGMDLLGPD----PSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDP 649
G++L PD P P ++QV + P GLR + P AQ + P
Sbjct: 2307 VDSPSSGTHLGGLELKTPDVFKAPLTPRASQV-----EPQSPGLGLRPQ-EPPPAQALAP 2360
Query: 650 GPA------LPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHF 703
P PGS + + Q R ES L P +LP PF
Sbjct: 2361 SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL------PPRSLPSDPFSRVPAS 2414
Query: 704 PKQLAKARALHSLSQLYSLSGC-----SRTQQPAPLAAPAAQVSVP---APSGEPQASTP 755
P+ + +++ + L + + C R Q P P + P ++ AP +P P
Sbjct: 2415 PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQP 2474
Query: 756 RATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPP 805
A KAGS TS LG+ + P GP+ + A PP
Sbjct: 2475 PEV---AFKAGSLAHTS----LGA-GGFPAALPAGPAGELHAKVPSGQPP 2516
Score = 33.9 bits (76), Expect = 1.2
Identities = 91/391 (23%), Positives = 120/391 (30%), Gaps = 53/391 (13%)
Query: 481 YTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRR 540
Y + N + R Q + ++G + R P P GSPP
Sbjct: 2060 YLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPA 2119
Query: 541 VTSFAELAKGRKKTGGS-----------GSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDE 589
+ G S GS P S G+ + P AQ P
Sbjct: 2120 AAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPF-- 2177
Query: 590 GTCCSHSLPP-MPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAG----LRATGQG-PL 643
G ++ L P P P P PSP + +S P AG T G P
Sbjct: 2178 GLAPAYPLEPRFPTAP--PTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPR 2235
Query: 644 AQLMDPGPAL-PGSPANSHTQRDARARADGGGT-----------ESRPVLRYSKEQRPTT 691
Q P P L P P+ + GG ESR L KE+ +
Sbjct: 2236 HQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGAS 2295
Query: 692 LPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQ 751
P + P L + S + L L + APL A+QV +P +
Sbjct: 2296 SP-------SYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLR 2348
Query: 752 ASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTAT 811
P A S P+ RP GSY+ + P P P P P +
Sbjct: 2349 PQEPPPAQALAPSPPSHPDIFRP---GSYTDPYAQPPLTPR----------PQPPPPESC 2395
Query: 812 ESLPPWSHSCPSAVRPATSQQPQKEDQKILT 842
+LPP S R S Q Q Q LT
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLT 2426
Score = 33.5 bits (75), Expect = 1.6
Identities = 103/448 (22%), Positives = 143/448 (31%), Gaps = 68/448 (15%)
Query: 430 PPGPGPDPGPSQPSEYYLFQKPEV-QPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPN 488
PP P P P+QP +P QP E T + +T P
Sbjct: 2197 PPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTP------------RHQPSTPDPF 2244
Query: 489 LSTGRQRSRSYDR-SLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAEL 547
L + R S D ++ SP V G L P E A+ + +
Sbjct: 2245 L---KPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKAL----EVKKEELGASSP 2297
Query: 548 AKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMD 607
+ G G SP +G + + +A A E L P P
Sbjct: 2298 SYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQA 2357
Query: 608 LLGPDPSPP-------WSTQVCQGPHSSE-MPPAGLRATGQGPLAQLMDPGPALPGSPAN 659
L PS P ++ Q P + PP P + DP +P SP +
Sbjct: 2358 LAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQS 2417
Query: 660 SH------TQRDARARADGGGTESRPVLRYSKEQRPTTLP--IQPFVFQHHFPKQLAKAR 711
T R A A + RP + P PF H P+
Sbjct: 2418 QSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEV 2477
Query: 712 ALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPET 771
A + S ++ G P A PA ++ PSG+P + R+ G GA
Sbjct: 2478 AFKAGSLAHTSLGAGGFPAALP-AGPAGELHAKVPSGQP-PNFVRSPGTGAF-------- 2527
Query: 772 SRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPA-TS 830
+G+ SP+R P + S PP QP LPP H S P T
Sbjct: 2528 -----VGTPSPMRFTFP-----QAVGEPSLKPPVPQP----GLPP-PHGINSHFGPGPTL 2572
Query: 831 QQPQKEDQKILTLTEYRLHGTGSLPPLG 858
+PQ + + T H +GS PLG
Sbjct: 2573 GKPQSTNYTVAT---GNFHPSGS--PLG 2595
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 51.6 bits (122), Expect = 6e-06
Identities = 107/480 (22%), Positives = 152/480 (31%), Gaps = 68/480 (14%)
Query: 405 SSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEV----QPEEQEA 460
S +S + SS+TS + +P GP + + P+V P +
Sbjct: 618 SLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKP 677
Query: 461 VSSSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSC 520
S + A A P V+ G V T + P +SPP +L +
Sbjct: 678 RSPNPAAPALAAPAVVPGPVSTTDASP-----------------QSPPTPQTTLTPLQES 720
Query: 521 PVRLSE-----GPAAMAGPGSPPRRVTSFAELAKGRKKTGGSG---------SPPLRVSV 566
PV + P P PP + A +T PP
Sbjct: 721 PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQ 780
Query: 567 GDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLG----------PDPSPP 616
S +F P +EA +P G S L P P P+PP
Sbjct: 781 DLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPP 840
Query: 617 WSTQVCQGP-HSSEMP---PAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADG 672
P H +++P P G + G GP + D G L +P+ R A G
Sbjct: 841 APAPASSAPGHVAKLPQKEPVGC-SKGGGPPRE--DVGAPLV-TPSLLQMVRLRSVGAPG 896
Query: 673 GGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPA 732
G P L S Q+P + P A L + G S Q
Sbjct: 897 GAPT--PALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNG 954
Query: 733 PLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSE----PETSRPSPLGSYSPIRSVGP 788
P P A+ P P P ++ +G+RK E PET + +RS+
Sbjct: 955 P---PEAE---PRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISE 1008
Query: 789 FGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSA---VRPATSQQPQKEDQKILTLTE 845
P S PP + + PP S S P A P T+ P +D+ L E
Sbjct: 1009 QRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAE 1068
Score = 46.2 bits (108), Expect = 2e-04
Identities = 105/430 (24%), Positives = 143/430 (33%), Gaps = 102/430 (23%)
Query: 427 ISPPPGP-GPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTS 485
++ P GP G P P + Q+P++ P S AA P N+
Sbjct: 512 LAVPDGPLGLPPKPERK------QQPQL-PRPPTTGGSEGAGAAPCPPNP------ANSW 558
Query: 486 PPNLSTG--RQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPR--RV 541
P LS G R+ RS +R+L SP S + P + GP A G PP+ RV
Sbjct: 559 VPGLSPGGSRRPPRSPERTL--SPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERV 616
Query: 542 TSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMP 601
TS + G S S L S+ SS + +P + PL + +PP P
Sbjct: 617 TSL-------RSPGASVSSSL-TSLCSSSSDPAPSDRSGPQILTPLGD----RFVIPPHP 664
Query: 602 LGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSH 661
P P PS P S + P A GP++ D P P +P +
Sbjct: 665 KVPAP--FSPPPSKPRSP-------NPAAPALAAPAVVPGPVSTT-DASPQSPPTPQTTL 714
Query: 662 TQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYS 721
T + PV+ SK+Q P P +
Sbjct: 715 TP-----------LQESPVI--SKDQSPPPSPPPSY------------------------ 737
Query: 722 LSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSR------PS 775
P P +V V APS A P PE P
Sbjct: 738 --------HPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPP 789
Query: 776 PLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHS---CPSAVRPATS-- 830
P ++ + S P GPS +S + TA + PP S P A PA+S
Sbjct: 790 PEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAP 849
Query: 831 ----QQPQKE 836
+ PQKE
Sbjct: 850 GHVAKLPQKE 859
Score = 36.6 bits (83), Expect = 0.19
Identities = 95/411 (23%), Positives = 137/411 (33%), Gaps = 74/411 (18%)
Query: 303 PQSCSDSSFCSHSDPGAFYLDLQPSPFESK---------MSYESHHPESGGREGGYGCPH 353
P S +D+S S P LQ SP SK SY P + E P
Sbjct: 696 PVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPS 755
Query: 354 ASS----PELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQS- 408
AS P D N + P P P DL S A + ++ + + + + S
Sbjct: 756 ASETAEEPLQDPN---WPPPPPPAPEEQDL-----SMADFPPPEEAFFSVASPEPAGPSG 807
Query: 409 ------SPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQP---EEQE 459
SP+ + SS T+ + PP P P P+ + ++ + P+ +P +
Sbjct: 808 SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGG 867
Query: 460 AVSSSTQAAAAVGPTVLE-----------GQVYTNTSPPNLSTGRQRSRSYDRSLQRSPP 508
A V P++L+ G P +R+ S S +P
Sbjct: 868 GPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPS 927
Query: 509 VRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGD 568
L + R+ +C + SEG + A P PP A+ R + + S G
Sbjct: 928 SGLHAAVRLKACSLAASEG-LSSAQPNGPPE--------AEPRPPQSPASTASFIFSKGS 978
Query: 569 SSQEF----SPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQG 624
+ SP +A R + E S PP P SP V +
Sbjct: 979 RKLQLERPVSPETQADLQRNL-VAELRSISEQRPPQ---------APKKSPKAPPPVARK 1028
Query: 625 PHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQ-RDARARADGGG 674
P PPA PL P G P HTQ R R A+ GG
Sbjct: 1029 PSVGVPPPASPSYPRAEPLT-----APPTNGLP---HTQDRTKRELAENGG 1071
>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
Length = 841
Score = 50.4 bits (119), Expect = 1e-05
Identities = 115/523 (21%), Positives = 177/523 (33%), Gaps = 109/523 (20%)
Query: 400 VTCDLSSQSSPSPAGSSIT----SCSEEHTKISPPPGPGPDPG-----------PSQPSE 444
+T S + +P P S++ SC + S GPG G P++P
Sbjct: 61 MTMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRR 120
Query: 445 YYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNL---STGRQRSRSYDR 501
+ + V P A + ++ A + PT EG+ + PP S Q S S+D
Sbjct: 121 HPSTKLSMVGPGSG-AETPPSKKAGSQKPTP-EGRESSRKVPPQKPRRSPNTQLSVSFDE 178
Query: 502 SLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPG----SPPRRVTSFAELAKGRKKTGGS 557
S P R G+L RL+ G P P + ++ +G ++GG
Sbjct: 179 SCPPGPSPRGGNLPLQ-----RLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGG 233
Query: 558 -------GSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLG 610
G P + DS E S + P + G ++ PP+
Sbjct: 234 LAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTA-------- 285
Query: 611 PDPSPPWSTQVCQGPHSSEMPPAGLRATGQG------------PLAQLMDPGPALPGSPA 658
SPP PH+ P + L + G P L+ P L P
Sbjct: 286 --TSPPQQPHALP-PHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFP- 341
Query: 659 NSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQ 718
Q + +R G G PVL +SKE +T P AR
Sbjct: 342 ----QAKSASRTPGDGVSRLPVLCHSKEPAGST------------PAPQVPAR------- 378
Query: 719 LYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLG 778
R P P PAA + + PSG ++ + +G+ +P R P
Sbjct: 379 -------ERETPPPPPPPPAANLLLLGPSGRARSHSTPLPPQGS----GQPRGERELP-N 426
Query: 779 SYSPIRSVGPFGPSTDSSASTSCSPPPEQPTAT-----ESLPPWSHSCPSAVRPATSQQP 833
S+S I P+ + + PP+ + ++ +HS A P + +P
Sbjct: 427 SHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSVLPAGPPLGAGEP 486
Query: 834 QKEDQKILTLTEYRLHG---TGSLPPLGSWRSGLSRAESLARG 873
+ E + + LHG T S PP+ S A A G
Sbjct: 487 KTEKEISV------LHGMLCTSSRPPVPGKTSPHGGAMGAAAG 523
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 50.1 bits (118), Expect = 2e-05
Identities = 136/601 (22%), Positives = 194/601 (32%), Gaps = 122/601 (20%)
Query: 401 TCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKP-EVQPEEQE 459
T + S P +G + ++T P PG G ++P L QK + EE
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP--LGQKGLRISAEETV 142
Query: 460 AVSSSTQAAAAVGPTVLEGQVYTNTSPPNLSTG------RQRSRSYDRSLQRSPPVRLGS 513
A +T+A + L +TS P T R R+ + L R P
Sbjct: 143 ARGKATEAPKR---SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS---- 195
Query: 514 LERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEF 573
+ P +EGP S T + A+ R GG P S+ S+
Sbjct: 196 -----ARPRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 574 S-PIQEAQQDRGAPLDEGTCCSHSLPPMPLG-----------PGMDL---LGPDPSPPWS 618
S P + RG P +H P P G P D LGP S P +
Sbjct: 250 SSPARSGPSARGTP----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 619 TQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPAL-------PGSPANSHTQRDARARAD 671
T G + +PP AT PL + P P L P SP+ + + +
Sbjct: 306 TPSPSGTKARPVPPPDNAAT---PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 672 GGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQP 731
+++ P + Q P +L P + H SL+ S P
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH------------------SLTSPSLQAPP 404
Query: 732 APLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGP 791
+PLA + Q + S QA+ T + S SRP+
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA---------------- 448
Query: 792 STDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKILTLTEYRLHGT 851
++ SPP + P + + PP S AV P +S LT + L
Sbjct: 449 -----STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS-----------PLTIHPLQAL 492
Query: 852 GSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREYRRKNPLGPPGLS 911
SL + S + SL E + P + P +L L PP L
Sbjct: 493 SSL----ASHSPQAPLSSLIMPPLETQSSLAPPSL-QTPPASLTTPPLENLPSLAPPPL- 546
Query: 912 GSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPDFQDPFSLTEKP 971
Q A P E P + C L P PLT P + P S+ P
Sbjct: 547 -------QTASAPLTTPHLETPPCPAP-----CPLQ---APPSPLTTPPPETPSSIATPP 591
Query: 972 P 972
P
Sbjct: 592 P 592
Score = 48.1 bits (113), Expect = 6e-05
Identities = 115/494 (23%), Positives = 159/494 (32%), Gaps = 80/494 (16%)
Query: 405 SSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEY--YLFQKPEVQPEEQEAVS 462
S Q+ PSP T S+ ++ PP P + P + P +Q
Sbjct: 353 SLQTLPSPPA---TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL 409
Query: 463 SSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPV 522
SS QA ++G L+ T P + S S S P L S P+
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469
Query: 523 RLSEGPAA--MAGPGS--PPRRVTSFAE---------LAKGRKKTGGSGSPPLRVSVGDS 569
+ S PA ++ P + P + ++S A L +T S +PP + S
Sbjct: 470 QTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS 529
Query: 570 ----------SQEFSPIQEAQQDRGAP-LDEGTC---CSHSLPPMPL------------- 602
S P+Q A P L+ C C PP PL
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT 589
Query: 603 ----------GPGMDLLGPDPSPPWSTQVCQGPHSSEMPP--AGLRATGQGPLAQLMDPG 650
P + L P P +T Q P +PP A PL+ L P
Sbjct: 590 PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649
Query: 651 PALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKA 710
P P + A Q A S PV + P + P+ P P Q +
Sbjct: 650 PQAPNALAVHLLQ------APFSPPPSPPV--QAPFSPPASPPVSPSATP---PSQAPPS 698
Query: 711 RALHSL--------SQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGA 762
A L S S S Q P PLAAP QV P+ P + + R
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Query: 763 RKAGSEPETSRPSPLGS--YSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHS 820
+ P PSP S SP+ P P ++ P P P + P+S S
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP--PASFPGQAPFSPS 816
Query: 821 CPSAVRPATSQQPQ 834
+ P + PQ
Sbjct: 817 ASLPMSPLATPPPQ 830
Score = 38.5 bits (88), Expect = 0.050
Identities = 67/268 (25%), Positives = 93/268 (34%), Gaps = 36/268 (13%)
Query: 736 APAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVG---PFGPS 792
A +V +P P+ + P R + + SE T+ PSP P G P S
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
Query: 793 TDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKIL---TLTEYRLH 849
SSA+ SP P+A P A PA QP+ + + L +T R
Sbjct: 242 LSSSATPLSSPARSGPSA--------RGTPRA--PAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 850 GTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQAL-KWREYRRKNPLGPP 908
+L PL S S + + G + P NA P L PL PP
Sbjct: 292 AAPALGPLSS-----SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346
Query: 909 GLSGSLDRRSQEARLARRNPIFEFPGSLSAASHLNCRLNGQAVKPLPLTCPDFQDPFSLT 968
S S Q P + P S++ P T P Q P SLT
Sbjct: 347 --SPSAPPSLQTLPSPPATPPSQAPPSMTTPP--------MQAPPSLQTIPPIQVPHSLT 396
Query: 969 ----EKPPAEFCLSPDGSSEAISIDLLQ 992
+ PP+ LS ++ ++ LQ
Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQ 424
Score = 33.1 bits (74), Expect = 2.1
Identities = 22/78 (28%), Positives = 29/78 (37%)
Query: 1292 PRGSSNSSSEKKKGAGGGGPPQAPPPREGVVEGAEACPASEEALGRERGWPFWMGSPPDS 1351
PR ++ S K KG PPQ PPR+ +S A G PPD+
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322
Query: 1352 VLAELRRSREREGPAASP 1369
L + P A+P
Sbjct: 323 AATPLPATLPPSPPLATP 340
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 49.3 bits (116), Expect = 3e-05
Identities = 185/850 (21%), Positives = 283/850 (33%), Gaps = 135/850 (15%)
Query: 64 SLLFSSLHSAPGGTARSIDSTKSRSRDGRGPGAPKRHNP-----FLLQEGVGEPGLGD-- 116
S +F S A G T S ST S GRG R +P L PGL +
Sbjct: 676 STIFHSSPDASGTTPSSAHSTTS----GRGESTTSRISPGSTEITTLPGSTTTPGLSEAS 731
Query: 117 --LYDDSIGDSATQQSFHLHGTGQPNFHLSSFQLPPSGPRVGRPWGTTRSRAGVVEGQEQ 174
Y + T + G +S P S P TT G +
Sbjct: 732 TTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTT------TPGLSE 785
Query: 175 EPVMTLDTQQCGTSHCCRPELEAETMELDECGGPGGSGSGGGASDTSGFSFDQEWKLSSD 234
E + + T P ++ +E P S ++ T+ F+ D ++
Sbjct: 786 ESTTVYSSSRGSTETTVFPHSTTTSVHGEE---PTTFHSRPASTHTTLFTEDSTTSGLTE 842
Query: 235 ESPRNPGCSGS--------------GDQHCRCSSTSSQ-----SEAADQSMGYVSDS--- 272
ES PG S G++ S+S S A + G V +S
Sbjct: 843 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPS 902
Query: 273 --SCNSSDGV----------LVTFSTLYNKMHGTPRANLNSAPQSCS---DSSFCSHSDP 317
S +S++ L ST + +P A L+ A + S + S SHS P
Sbjct: 903 RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQP 962
Query: 318 GAFYLDLQP-SPFESKMSYE--SHHPESGGREGGYGCPHASSPELDANCNSYRPHCEPCP 374
G+ + P S S +S E + H G E ++ L ++ H P
Sbjct: 963 GSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF--HSSPGD 1020
Query: 375 AVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKI------- 427
L + LV A+ + S ++ +PA S+ EE T
Sbjct: 1021 TETTLLPDDTITSGLVEASTPTHSSTG---SLHTTLTPASSTSAGLQEESTTFQSWPSSS 1077
Query: 428 -SPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSP 486
+ P PG P + S Y +P P + SS+T + TV ++SP
Sbjct: 1078 DTTPSPPGTTAAPVEVSTTY-HSRPSSTPTTHFSASSTTLGRSEESTTV-------HSSP 1129
Query: 487 PNLSTGRQRSRSYDRSLQRSP---PVRLGSLERML----SCPVRLSEGPAAM-AGPGSP- 537
T +RS L P P+ GS E + LSE + P SP
Sbjct: 1130 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPD 1189
Query: 538 ----PRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCC 593
P TS + GS G ++ QE+ +P T
Sbjct: 1190 TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP-GVSQESTASHSSPGSTDTTL 1248
Query: 594 SHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPAL 653
S P LGP+ ST P S+E T G L + P +
Sbjct: 1249 S------PGSTTASSLGPE-----STTFHSSPGSTETTLLPDNTTASG-LLEASTPVHSS 1296
Query: 654 PGSPANSHTQRDARARADGGGT-ESRPVLRYSKEQRPTTLP--IQPFVFQHHFPKQLAKA 710
GSP + + + R T +S P + + PTT ++ H P
Sbjct: 1297 TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTT 1356
Query: 711 RALHSLSQLYSLSGCSRTQQPAPL-AAPAAQVSVPAP-----SGEPQASTPRATGRGARK 764
S + L R+++ + ++P A + P+P SG + ST + G+ +
Sbjct: 1357 HFSASSTTL------GRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQ 1410
Query: 765 AGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSA 824
PE+S S S ++ SS + + S PP +A P HS P +
Sbjct: 1411 TMHFPESSTASGRSEESR---------TSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS 1461
Query: 825 VRPATSQQPQ 834
+ AT+ P+
Sbjct: 1462 I--ATTHFPE 1469
Score = 39.3 bits (90), Expect = 0.029
Identities = 130/639 (20%), Positives = 194/639 (30%), Gaps = 75/639 (11%)
Query: 216 GASDTSGFSFDQEWKLSSDESPRNPGCSG-SGDQHCRCSSTSSQSEAADQSMGYVSDSSC 274
G S TS S + S PG S S H S ++ A + VS+ S
Sbjct: 423 GESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEEST 482
Query: 275 NSSDGVLVTFSTLYNKMHGTPRANLNSAPQSCSDSSFCSHSDPGAFYLDLQP-SPFESKM 333
S T +T + TP S S SHS PG+ L P S S
Sbjct: 483 TSRSRPGSTHTTAFPDSTTTP---------GLSRHSTTSHSSPGSTDTTLLPASTTTSGP 533
Query: 334 SYESHHPESGGREGGYGCPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVAT 393
S ES S S+ L S H P L + + +V A+
Sbjct: 534 SQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAS 593
Query: 394 QNYYKLV-----TCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLF 448
+ T +S +SP G S + + + P P P + S Y
Sbjct: 594 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY-H 652
Query: 449 QKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSP- 507
+ P P SS+T + T+ + + P+ + R + + SP
Sbjct: 653 RSPGSTPTTHFPASSTTSGHSEKS-TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 711
Query: 508 PVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVT--SFAELAKGRKKTGGSGSPPLRVS 565
+ +L + P + P SP ++ S L G + T P S
Sbjct: 712 STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS 771
Query: 566 VGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGP 625
+ +P + + + S P + G +P+
Sbjct: 772 TVSPASTTTP---GLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTF--------- 819
Query: 626 HSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSK 685
HS T + L + A PGSPA++ T A G ES
Sbjct: 820 HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEES-------- 871
Query: 686 EQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPA 745
TT P S SG + T+ + + V
Sbjct: 872 ----TTFP---------------------------SSSGSTGTKLSPARSTTSGLVGEST 900
Query: 746 PSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPP 805
PS +ST T G+ S E S SP ++ P +T S S S
Sbjct: 901 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP-ATTTSSGVSEESSTSH 959
Query: 806 EQP--TATESLPPWSHSCPSAVRPATSQQPQKEDQKILT 842
QP T T + P + + + P TS Q + L+
Sbjct: 960 SQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 998
Score = 38.5 bits (88), Expect = 0.050
Identities = 133/638 (20%), Positives = 212/638 (33%), Gaps = 77/638 (12%)
Query: 256 SSQSEAADQSMGYVSDSSCNSSDGVLVTFSTLYNKMHGTPRANLNSAPQSC--SDSSFCS 313
S+ S + SM + + G+ +T Y+ +L ++ S S+ S S
Sbjct: 95 STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTS 154
Query: 314 HSDPGAFYLDLQPSPF-------ESKMSYESHHPESGGREGGYGCPHASSPELDANCNSY 366
HS PG+ + P ES S+ S P G + PE
Sbjct: 155 HSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTF---- 210
Query: 367 RPHCEPCPAVADLTACFQSQARLVVATQNYYKLVTCDLSSQSSPSPAGSSITSCSEEHTK 426
H P L + + L+ A+ + S ++ SPAGS+ T E T
Sbjct: 211 --HSRPGSTETTLLPDNTTASGLLEASMPVHSSTR---SPHTTLSPAGST-TRQGESTTF 264
Query: 427 ISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSP 486
S P P P P+ F +P + +T +A + L + T S
Sbjct: 265 HSWPSSKDTRPAP--PTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSS 322
Query: 487 P-----------NLSTGR-QRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGP 534
P + ++GR + S + S + + ++ P P + A
Sbjct: 323 PGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATT 382
Query: 535 GSPPRRVTS--FAELAKGRKKTGGSGSPPL------RVSVGDSSQEFSPIQEAQQDRGA- 585
P TS E +G+ L V +G+S+ SPI + A
Sbjct: 383 HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTT--SPISSGSMETTAL 440
Query: 586 -------PLDEGTCCSHSLPPMP---LGPGMDLLG-------PDPSPPWSTQVCQGPHSS 628
L E + HS P P L P S P ST P S+
Sbjct: 441 PGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDST 500
Query: 629 EMPPAGLRATGQGPLAQLMDPGPALPGSPANSH-TQRDARARADGGGTESR----PVLRY 683
P +T D LP S S +Q + + G T++
Sbjct: 501 TTPGLSRHSTTSHSSPGSTDT-TLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTAL 559
Query: 684 SKEQRPTTLPIQP-FVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVS 742
S Q TT P FP + + + ++++S +G RT +PA+ S
Sbjct: 560 SFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT-----LSPASSTS 614
Query: 743 VPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCS 802
P GE ST T + P ++ +P+ + P+T AS++ S
Sbjct: 615 -PGLQGE---STAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS 670
Query: 803 PPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQKI 840
E+ T S P S + PS+ TS + + +I
Sbjct: 671 GHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 708
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 49.3 bits (116), Expect = 3e-05
Identities = 111/494 (22%), Positives = 157/494 (31%), Gaps = 115/494 (23%)
Query: 275 NSSDGVLVTFSTLYNKMHGTPRANLNSAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMS 334
NSS+ + ++ K+H P +L + P+S + + H YL +P +
Sbjct: 1423 NSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHG-----YLSPKPPSQQLGSP 1477
Query: 335 YESHHPESGGREGGYGCPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQ 394
Y HH +S P +P+ + N Y PA +L A Q + TQ
Sbjct: 1478 YRPHHSQS---------PQVGTPQREPQRNFY-------PAAQNLPANTQQATSGTLFTQ 1521
Query: 395 NYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEV- 453
+P+G S + S+ + + P P P P S YY Q+P
Sbjct: 1522 ----------------TPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSAN 1565
Query: 454 -QPEEQEAVSSSTQAAAAVGPT-VLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRL 511
Q Q S S Q GP L G T P + T S + ++
Sbjct: 1566 FQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHH------ 1619
Query: 512 GSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQ 571
+ AA+ P PP P V +S Q
Sbjct: 1620 --------------QTAAAVVPPPPPPPPAPG-----------------PHLVQQPNSHQ 1648
Query: 572 EFS------PIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGP 625
+ S P+ G+ + T H LPP P PG P PP P
Sbjct: 1649 QHSVAHVVGPVHAVTP--GSHIHSQT-AGHHLPPPPPPPGP---APHHHPP--------P 1694
Query: 626 HSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSK 685
H P GL+ Q +++ P P P S A G T S L +
Sbjct: 1695 H----PSTGLQGL-QAQHQHVVNSAPPPPPPPPPS------SVLASGHHTTSAQALHHPP 1743
Query: 686 EQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPA 745
Q P P +P Q L Q + SG + P P+ P Q
Sbjct: 1744 HQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQ-HQPSG-TGPHCPLPVTGPHLQ----- 1796
Query: 746 PSGEPQASTPRATG 759
P G TP A+G
Sbjct: 1797 PQGPNSIPTPTASG 1810
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 49.3 bits (116), Expect = 3e-05
Identities = 111/494 (22%), Positives = 157/494 (31%), Gaps = 115/494 (23%)
Query: 275 NSSDGVLVTFSTLYNKMHGTPRANLNSAPQSCSDSSFCSHSDPGAFYLDLQPSPFESKMS 334
NSS+ + ++ K+H P +L + P+S + + H YL +P +
Sbjct: 1423 NSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHG-----YLSPKPPSQQLGSP 1477
Query: 335 YESHHPESGGREGGYGCPHASSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQ 394
Y HH +S P +P+ + N Y PA +L A Q + TQ
Sbjct: 1478 YRPHHSQS---------PQVGTPQREPQRNFY-------PAAQNLPANTQQATSGTLFTQ 1521
Query: 395 NYYKLVTCDLSSQSSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEV- 453
+P+G S + S+ + + P P P P S YY Q+P
Sbjct: 1522 ----------------TPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSAN 1565
Query: 454 -QPEEQEAVSSSTQAAAAVGPT-VLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRL 511
Q Q S S Q GP L G T P + T S + ++
Sbjct: 1566 FQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHH------ 1619
Query: 512 GSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQ 571
+ AA+ P PP P V +S Q
Sbjct: 1620 --------------QTAAAVVPPPPPPPPAPG-----------------PHLVQQPNSHQ 1648
Query: 572 EFS------PIQEAQQDRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGP 625
+ S P+ G+ + T H LPP P PG P PP P
Sbjct: 1649 QHSVAHVVGPVHAVTP--GSHIHSQT-AGHHLPPPPPPPGP---APHHHPP--------P 1694
Query: 626 HSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSK 685
H P GL+ Q +++ P P P S A G T S L +
Sbjct: 1695 H----PSTGLQGL-QAQHQHVVNSAPPPPPPPPPS------SVLASGHHTTSAQALHHPP 1743
Query: 686 EQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPA 745
Q P P +P Q L Q + SG + P P+ P Q
Sbjct: 1744 HQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQ-HQPSG-TGPHCPLPVTGPHLQ----- 1796
Query: 746 PSGEPQASTPRATG 759
P G TP A+G
Sbjct: 1797 PQGPNSIPTPTASG 1810
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 49.3 bits (116), Expect = 3e-05
Identities = 145/643 (22%), Positives = 216/643 (33%), Gaps = 107/643 (16%)
Query: 343 GGREGGYGCPHA-----SSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYY 397
GG GGYG A SSP P +++ A + A QN +
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353
Query: 398 KLVTCDLSSQ--SSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQP 455
+Q +SPSP S E++ S PP P PSQ P+ Q
Sbjct: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPP-----PPPSQ---------PQSQA 399
Query: 456 EEQEAVSSSTQAAAAVGPTVLEGQVYTNTSP-----------------PNLSTGRQRSRS 498
A + QAAA +G G Y SP P + GR +
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSP 459
Query: 499 YDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSG 558
D + + P + G S P + S P GP P R +GR +G
Sbjct: 460 MDPMVMKRPQL-YGMGSNPHSQPQQSSPYPGGSYGPPGPQRYPIGI----QGRTPGAMAG 514
Query: 559 SP-PLRVSVGDSSQE----FSPIQEAQQDRGAPLDEGTCCSHSLPPMP--LGPGMDLLGP 611
P + GD++ + P Q QQ +G +S P P L P L
Sbjct: 515 MQYPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL-- 572
Query: 612 DPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLA------------QLMDPG--PALPGSP 657
P S Q Q +M G Q PLA Q P P L GS
Sbjct: 573 ---PSQSQQRYQ--PQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSI 627
Query: 658 ANSHTQRDA---RARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALH 714
+ T +A A + G T S+ + P P P H L+
Sbjct: 628 DDLPTGTEATLSSAVSASGSTSSQ-----GDQSNPAQSPFSP-----HASPHLSSIPGGP 677
Query: 715 SLSQLYSLSGC--SRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRG--ARKAGSEPE 770
S S + S G SR+ +P + P +Q+ P + ++S+ A + ++ G
Sbjct: 678 SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAG 737
Query: 771 TSRPSPLGSYSPIRSVGPFGPSTD---------SSASTSCSPPPEQPTATESLPPWSHSC 821
T R + Y P ++ P SS S S P ++ P ++S
Sbjct: 738 TQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSR 797
Query: 822 PSAVRPATSQQPQKEDQKILTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMAT 881
P A S + ++HG G P G+ G + + G+M++
Sbjct: 798 PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 857
Query: 882 RPSNANHLSPQALKWREYRRKNPLGPPGLSGSLDRRSQEARLA 924
++ +S Q +GPP +++R++QEA A
Sbjct: 858 MTPSSPGMSQQG--------GPGMGPP--MPTVNRKAQEAAAA 890
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 49.3 bits (116), Expect = 3e-05
Identities = 143/638 (22%), Positives = 211/638 (33%), Gaps = 110/638 (17%)
Query: 343 GGREGGYGCPHA-----SSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYY 397
GG GGYG A SSP P +++ A + A QN +
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353
Query: 398 KLVTCDLSSQ--SSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQP 455
+Q +SPSP S E++ S PP P PSQ P+ Q
Sbjct: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPP-----PPPSQ---------PQSQA 399
Query: 456 EEQEAVSSSTQAAAAVGPTVLEGQVYTNTSP-----------------PNLSTGRQRSRS 498
A + QAAA +G G Y SP P + GR +
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSP 459
Query: 499 YDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSG 558
D + + P + G S P + S P GP P R G G
Sbjct: 460 MDPMVMKRPQL-YGMGSNPHSQPQQSSPYPGGSYGPPGPQ------------RYPIGIQG 506
Query: 559 SPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMP--LGPGMDLLGPDPSPP 616
P ++ Q+ P Q QQ +G +S P P L P L P
Sbjct: 507 RTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL-----PS 561
Query: 617 WSTQVCQGPHSSEMPPAGLRATGQGPLA------------QLMDPG--PALPGSPANSHT 662
S Q Q +M G Q PLA Q P P L GS + T
Sbjct: 562 QSQQRYQ--PQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPT 619
Query: 663 QRDA---RARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQL 719
+A A + G T S+ + P P P H L+ S S +
Sbjct: 620 GTEATLSSAVSASGSTSSQ-----GDQSNPAQSPFSP-----HASPHLSSIPGGPSPSPV 669
Query: 720 YSLSGC--SRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRG--ARKAGSEPETSRPS 775
S G SR+ +P + P +Q+ P + ++S+ A + ++ G T R
Sbjct: 670 GSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNP 729
Query: 776 PLGSYSPIRSVGPFGPSTD---------SSASTSCSPPPEQPTATESLPPWSHSCPSAVR 826
+ Y P ++ P SS S S P ++ P ++S P A
Sbjct: 730 QMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYS 789
Query: 827 PATSQQPQKEDQKILTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNA 886
S + ++HG G P G+ G + + G+M++ ++
Sbjct: 790 GVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 849
Query: 887 NHLSPQALKWREYRRKNPLGPPGLSGSLDRRSQEARLA 924
+S Q +GPP +++R++QEA A
Sbjct: 850 PGMSQQG--------GPGMGPP--MPTVNRKAQEAAAA 877
Score = 35.0 bits (79), Expect = 0.55
Identities = 89/420 (21%), Positives = 137/420 (32%), Gaps = 92/420 (21%)
Query: 409 SPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQP-------SEYYLFQKPEVQPEEQEAV 461
SPSP GS + S ISP PG P P S L Q P Q A
Sbjct: 665 SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAG 724
Query: 462 SSSTQAAAAVGPTVLEGQVYTNTSP-----PNLSTGRQRSRSYDRSLQRS---------- 506
+ A GP + + SP +S+ +Q + S Q S
Sbjct: 725 TQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSR 784
Query: 507 PPVRLGSLERMLSCP-----------------------VRLSEGPAAMAGPGSPPRRVTS 543
PP G S P V L P+A P ++S
Sbjct: 785 PPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSS 844
Query: 544 FAELAKGRKKTGGSGSPPLRVSVGDSSQEF------SPIQEAQQDRGA---PLDEGTCCS 594
+ G + GG G P +V +QE + AQ +G+ G S
Sbjct: 845 MTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMAS 904
Query: 595 HSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQG-PLAQLMDPGPAL 653
S P+ L+ +PP+S M PA + ++ LA +M PG +
Sbjct: 905 SSPYSQPMNNSSSLMNTQ-APPYS-----------MAPAMVNSSAASVGLADMMSPGESK 952
Query: 654 PGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARAL 713
P + + + + + +S S+ P LP+ P ++ + A
Sbjct: 953 LPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPV---------PSPMSPSSA- 1002
Query: 714 HSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKA---GSEPE 770
S+S + + +++P P P++S+ TG K G+EPE
Sbjct: 1003 -SISSFHG-------DESDSISSP----GWPKTPSSPKSSSSTTTGEKITKVYELGNEPE 1050
Score = 33.1 bits (74), Expect = 2.1
Identities = 60/310 (19%), Positives = 112/310 (36%), Gaps = 42/310 (13%)
Query: 364 NSYRPHCEPCPAVADLTACFQSQARLVVATQNYYKL-VTCDLSSQSSPSPAGSSITSCSE 422
N+ P PA+ + +A A ++ ++ L + D + +P P S S S
Sbjct: 920 NTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKDSYSS 979
Query: 423 EHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYT 482
+ P PG P P P PS + +E +++SS P
Sbjct: 980 QGISQPPTPGNLPVPSPMSPSSASI---SSFHGDESDSISSPGWPKTPSSP--------- 1027
Query: 483 NTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPP---- 538
S + +TG + ++ Y+ + P R ++R L+ +++ G P
Sbjct: 1028 -KSSSSTTTGEKITKVYELG---NEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLF 1083
Query: 539 ------RRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTC 592
+ + A++ K +K ++VG SS S +++ +
Sbjct: 1084 RLYVCVKEIGGLAQVNKNKKWR----ELATNLNVGTSSSAASSLKKQYIQYLFAFECKIE 1139
Query: 593 CSHSLPPMPLGPGMDLLGP--DPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPG 650
PP G P P P ++ QGP + + +TG +A++ PG
Sbjct: 1140 RGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQ-------STGSNSMAEV--PG 1190
Query: 651 PALPGSPANS 660
P +PA++
Sbjct: 1191 DLKPPTPAST 1200
Score = 32.3 bits (72), Expect = 3.6
Identities = 79/333 (23%), Positives = 112/333 (33%), Gaps = 67/333 (20%)
Query: 737 PAAQVSVPAPS-GEPQAST--------PRATGRGARKAGSEPETSRPSPLGSYSPIRSVG 787
PA P P+ G Q S P+ G G+ S+P+ S P P GSY G
Sbjct: 441 PAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPH-SQPQQSSPYPGGSY------G 493
Query: 788 PFGP--------STDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQK 839
P GP A P +Q S C +P SQQPQ
Sbjct: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQ--PPH 551
Query: 840 ILTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREY 899
+ +Y LP R + S G P NH +
Sbjct: 552 LPPQAQY-------LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLI----- 599
Query: 900 RRKNPLGPPGLSGSLD--RRSQEARLA--------------RRNPIFEFPGSLSAASHLN 943
+++ P P LSGS+D EA L+ + NP + P S A+ HL+
Sbjct: 600 QQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA-QSPFSPHASPHLS 658
Query: 944 CRLNGQAVKPLPLTCPDFQD---PFSLTEKPPAEFCLSPDGS-SEAISIDLLQKKGLVKA 999
G + P+ Q P S P ++ P GS SE+ S L + + +
Sbjct: 659 SIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQE 718
Query: 1000 VNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNV 1032
GT R+P + A+ G P++
Sbjct: 719 RGFMA-------GTQRNPQM-AQYGPQQTGPSM 743
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 49.3 bits (116), Expect = 3e-05
Identities = 143/638 (22%), Positives = 211/638 (33%), Gaps = 110/638 (17%)
Query: 343 GGREGGYGCPHA-----SSPELDANCNSYRPHCEPCPAVADLTACFQSQARLVVATQNYY 397
GG GGYG A SSP P +++ A + A QN +
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQH 353
Query: 398 KLVTCDLSSQ--SSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQP 455
+Q +SPSP S E++ S PP P PSQ P+ Q
Sbjct: 354 PSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPP-----PPPSQ---------PQSQA 399
Query: 456 EEQEAVSSSTQAAAAVGPTVLEGQVYTNTSP-----------------PNLSTGRQRSRS 498
A + QAAA +G G Y SP P + GR +
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSP 459
Query: 499 YDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELAKGRKKTGGSG 558
D + + P + G S P + S P GP P R G G
Sbjct: 460 MDPMVMKRPQL-YGMGSNPHSQPQQSSPYPGGSYGPPGPQ------------RYPIGIQG 506
Query: 559 SPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMP--LGPGMDLLGPDPSPP 616
P ++ Q+ P Q QQ +G +S P P L P L P
Sbjct: 507 RTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYL-----PS 561
Query: 617 WSTQVCQGPHSSEMPPAGLRATGQGPLA------------QLMDPG--PALPGSPANSHT 662
S Q Q +M G Q PLA Q P P L GS + T
Sbjct: 562 QSQQRYQ--PQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPT 619
Query: 663 QRDA---RARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQL 719
+A A + G T S+ + P P P H L+ S S +
Sbjct: 620 GTEATLSSAVSASGSTSSQ-----GDQSNPAQSPFSP-----HASPHLSSIPGGPSPSPV 669
Query: 720 YSLSGC--SRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRG--ARKAGSEPETSRPS 775
S G SR+ +P + P +Q+ P + ++S+ A + ++ G T R
Sbjct: 670 GSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNP 729
Query: 776 PLGSYSPIRSVGPFGPSTD---------SSASTSCSPPPEQPTATESLPPWSHSCPSAVR 826
+ Y P ++ P SS S S P ++ P ++S P A
Sbjct: 730 QMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYS 789
Query: 827 PATSQQPQKEDQKILTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNA 886
S + ++HG G P G+ G + + G+M++ ++
Sbjct: 790 GVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSS 849
Query: 887 NHLSPQALKWREYRRKNPLGPPGLSGSLDRRSQEARLA 924
+S Q +GPP +++R++QEA A
Sbjct: 850 PGMSQQG--------GPGMGPP--MPTVNRKAQEAAAA 877
Score = 32.3 bits (72), Expect = 3.6
Identities = 79/333 (23%), Positives = 112/333 (33%), Gaps = 67/333 (20%)
Query: 737 PAAQVSVPAPS-GEPQAST--------PRATGRGARKAGSEPETSRPSPLGSYSPIRSVG 787
PA P P+ G Q S P+ G G+ S+P+ S P P GSY G
Sbjct: 441 PAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPH-SQPQQSSPYPGGSY------G 493
Query: 788 PFGP--------STDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATSQQPQKEDQK 839
P GP A P +Q S C +P SQQPQ
Sbjct: 494 PPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQ--PPH 551
Query: 840 ILTLTEYRLHGTGSLPPLGSWRSGLSRAESLARGGGEGSMATRPSNANHLSPQALKWREY 899
+ +Y LP R + S G P NH +
Sbjct: 552 LPPQAQY-------LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLI----- 599
Query: 900 RRKNPLGPPGLSGSLD--RRSQEARLA--------------RRNPIFEFPGSLSAASHLN 943
+++ P P LSGS+D EA L+ + NP + P S A+ HL+
Sbjct: 600 QQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPA-QSPFSPHASPHLS 658
Query: 944 CRLNGQAVKPLPLTCPDFQD---PFSLTEKPPAEFCLSPDGS-SEAISIDLLQKKGLVKA 999
G + P+ Q P S P ++ P GS SE+ S L + + +
Sbjct: 659 SIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQE 718
Query: 1000 VNIAVDLIVAHFGTSRDPGVKAKLGNSSVSPNV 1032
GT R+P + A+ G P++
Sbjct: 719 RGFMA-------GTQRNPQM-AQYGPQQTGPSM 743
>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
Length = 957
Score = 48.9 bits (115), Expect = 4e-05
Identities = 85/320 (26%), Positives = 120/320 (37%), Gaps = 66/320 (20%)
Query: 601 PLGPGM--DLLGPD-PSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSP 657
P PG+ D+ G D P P +Q+ QG +SE P + T P +P +
Sbjct: 31 PNAPGLPADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAE------GPSTFVPPTI 84
Query: 658 ANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLS 717
+ + + ++G GT VL E T+ P P + ++ L +
Sbjct: 85 SEASSASGQPTISEGPGTS---VLPTPSEGLSTSGP--PTI-----------SKGLCTSV 128
Query: 718 QLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPL 777
L + G + ++ P P+ V P S P S P G G + S P T+ P
Sbjct: 129 TLAASEGRNTSRPPTSSEEPSTSVP-PTASEVPSTSLPPTPGEGT--STSVPPTAYEGPS 185
Query: 778 GSYSPIRSVGPF---------GPSTD------SSASTSCSPPPEQ-------PTATESL- 814
S P GP GP T STS P++ PTATE L
Sbjct: 186 TSVVPTPDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLS 245
Query: 815 ---PPWSHSCPSAVRPAT-------SQQPQKEDQKILTLTEYRLHGTG-SLPPLGSWRSG 863
PP PS PAT S P D + ++L R G+ S+PP + G
Sbjct: 246 TPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTAT--EG 303
Query: 864 LSRAESLARGGGEGSMATRP 883
LS S+ GEGS + P
Sbjct: 304 LS--TSVQPTAGEGSSTSVP 321
Score = 38.5 bits (88), Expect = 0.050
Identities = 69/280 (24%), Positives = 91/280 (32%), Gaps = 25/280 (8%)
Query: 408 SSPSPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQA 467
SS P+ +S+ + E S PP PG S P Y V P E S+S
Sbjct: 144 SSEEPS-TSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLP 202
Query: 468 AAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPV--RLS 525
GP G + LST Q + S P G LS PV
Sbjct: 203 TPGEGP----GTSVPLAATEGLSTSVQATPDEGPSTSVPPTATEG-----LSTPVPPTRD 253
Query: 526 EGPAAM--AGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDR 583
EGP+ A PG P TS A + G + SS P
Sbjct: 254 EGPSTSVPATPGEGPS--TSVLPAA-----SDGQSISLVPTRGKGSSTSVPPTATEGLST 306
Query: 584 GAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQV----CQGPHSSEMPPAGLRATG 639
G S S+PP P G + P + ST V +GP +S +P G +
Sbjct: 307 SVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLST 366
Query: 640 QGPLAQLMDPGPALPGSPANSHTQRDARARADGGGTESRP 679
P ++P +P + DG G+ P
Sbjct: 367 SVPPTASDGSDTSVPPTPGEGASTLVQPTAPDGPGSSVLP 406
Score = 36.2 bits (82), Expect = 0.25
Identities = 93/404 (23%), Positives = 137/404 (33%), Gaps = 69/404 (17%)
Query: 429 PPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPPN 488
P PG D P PS+ + Q + +S + +V PT EG + PP
Sbjct: 37 PADVPGSDV-PQGPSDSQILQ----------GLCASEGPSTSVLPTSAEGP--STFVPPT 83
Query: 489 LSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFAELA 548
+S S P + G +L P SEG + +GP + + + + LA
Sbjct: 84 ISEASSASGQ--------PTISEGPGTSVLPTP---SEG-LSTSGPPTISKGLCTSVTLA 131
Query: 549 KGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAPLDEGTCCSHSLPPMPL-GPGMD 607
+ + PP S + S P P G S S+PP GP
Sbjct: 132 ASEGRN--TSRPP--TSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTS 187
Query: 608 LLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPGPALPGSPANSHTQRDAR 667
++ P+P +GP +S +P G PLA ++ +P +
Sbjct: 188 VV---PTPD------EGPSTSVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPSTSVPP 238
Query: 668 ARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSR 727
+G T PV E T++P P + L A S+S + + S
Sbjct: 239 TATEGLST---PVPPTRDEGPSTSVPATPG--EGPSTSVLPAASDGQSISLVPTRGKGSS 293
Query: 728 TQQPAPLAAPAAQVSVPAPSGEPQA-STPRATGRGARKAGSEPETSRPSPLGSYSPIRSV 786
T P P A SV +GE + S P G G TS P
Sbjct: 294 TSVP-PTATEGLSTSVQPTAGEGSSTSVPPTPGGGL-------STSVP------------ 333
Query: 787 GPFGPSTDSSASTSCSPPPEQPTATESLPPWSHSCPSAVRPATS 830
P+ STS P P + +T LP ++V P S
Sbjct: 334 ----PTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPPTAS 373
Score = 33.5 bits (75), Expect = 1.6
Identities = 74/324 (22%), Positives = 110/324 (33%), Gaps = 36/324 (11%)
Query: 534 PGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSP-IQEAQQDRGAP-LDEGT 591
PGS + S +++ +G + G + L S S P I EA G P + EG
Sbjct: 41 PGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEASSASGQPTISEGP 100
Query: 592 CCSHSLPPMPLGPGMDLLGPDPSPPWSTQVC--------QGPHSSEMPPAGLRATGQGPL 643
S+ P P G+ GP P S +C +G ++S P + + P
Sbjct: 101 --GTSVLPTP-SEGLSTSGP---PTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPP 154
Query: 644 AQLMDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHF 703
P +LP +P + +G T P + ++ P+T +
Sbjct: 155 TASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVP----TPDEGPSTSVLPTPGEGPGT 210
Query: 704 PKQLAKARALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVPAPSGE-PQASTPRATGRGA 762
LA L + Q G S T P P A VP E P S P G G
Sbjct: 211 SVPLAATEGLSTSVQATPDEGPS-TSVP-PTATEGLSTPVPPTRDEGPSTSVPATPGEGP 268
Query: 763 RK----AGSEPETSRPSPLGSYSPIRSVGPFG---------PSTDSSASTSCSPPPEQPT 809
A S+ ++ P SV P P+ +STS P P
Sbjct: 269 STSVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGL 328
Query: 810 ATESLPPWSHSCPSAVRPATSQQP 833
+T P + ++V P + P
Sbjct: 329 STSVPPTATEELSTSVPPTPGEGP 352
>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
Length = 379
Score = 48.9 bits (115), Expect = 4e-05
Identities = 83/313 (26%), Positives = 114/313 (36%), Gaps = 62/313 (19%)
Query: 534 PGSPPRRVTSFAELA----KGRKKTGGSGSPPLRV-SVGDSSQEFSPIQEAQQDRGAPLD 588
PG P A++A +G ++ GG G P V S + +P
Sbjct: 97 PGVPNTAAGEDADVAACPRRGEEEEGGGGFPHFGVRSCAPPGRCPAPPHPR--------- 147
Query: 589 EGTCCSHSLPPMPLGPGMD-LLGPDPSPPWSTQVCQGPHSSE-MPPAGLRATGQGPLAQL 646
E T S PP P PG++ GP SPP Q P S PPAGL GP
Sbjct: 148 ESTTSFASAPPRP-APGLEPQRGPAASPP------QEPSSRPPSPPAGLSTEPAGPGTA- 199
Query: 647 MDPGPALPGSPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQP-FVFQHHFPK 705
P P LPG P A DG + P + + P P + Q HF +
Sbjct: 200 --PRPFLPGQP----------AEVDGNPPPAAPEAPAASPSTASPAPAAPGDLRQEHFDR 247
Query: 706 QLAKARALHSLSQLYSLS------GCSRTQQPAPLAAPAAQVSVPAPSGEPQASTPRATG 759
+ +++ L ++ ++L G R P A + +PAP P+ + PR
Sbjct: 248 LIRRSK-LWCYAKGFALDTPSLRRGPERPPAKGPARGAAKKRRLPAP--PPRTAQPR--- 301
Query: 760 RGARKAGSEPETSRPSPLGSY--SPIRSVGPFG---PSTDSSASTSCSPPPEQPTATESL 814
R A + P TS S L + P VG G P++ PPP P L
Sbjct: 302 ---RPAPTLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQGDSKPPPAHP-----L 353
Query: 815 PPWSHSCPSAVRP 827
W P+ P
Sbjct: 354 WRWQMGGPAVPEP 366
Score = 31.2 bits (69), Expect = 8.0
Identities = 61/251 (24%), Positives = 82/251 (32%), Gaps = 59/251 (23%)
Query: 428 SPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGP-TVLEGQVY----- 481
S PP P P P + Q+P +P A S+ A P L GQ
Sbjct: 155 SAPPRPAPGLEPQRGPAASPPQEPSSRPPSPPAGLSTEPAGPGTAPRPFLPGQPAEVDGN 214
Query: 482 -------------TNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVR--LSE 526
+ SP + G R +DR ++RS L C + +
Sbjct: 215 PPPAAPEAPAASPSTASPAPAAPGDLRQEHFDRLIRRS----------KLWCYAKGFALD 264
Query: 527 GPAAMAGPGSPPRRVTSFAELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDRGAP 586
P+ GP PP + A+G K +PP R AQ R AP
Sbjct: 265 TPSLRRGPERPPAKGP-----ARGAAKKRRLPAPPPRT--------------AQPRRPAP 305
Query: 587 LDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQL 646
T L P P + + P S+ QG S+ PPA PL +
Sbjct: 306 TLPTTSTFSLLNCFPCPPALVVGEDGDLKPASSLRLQG--DSKPPPA-------HPLWRW 356
Query: 647 MDPGPALPGSP 657
GPA+P P
Sbjct: 357 QMGGPAVPEPP 367
>gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]
Length = 1374
Score = 48.5 bits (114), Expect = 5e-05
Identities = 103/412 (25%), Positives = 146/412 (35%), Gaps = 81/412 (19%)
Query: 428 SPPPGPGPDPGPSQPSEYYLFQKPEVQPEEQEAVSSSTQAAAAVGPTVLEGQVYTNTSPP 487
+P G PD PS P ++ + ST A+ A+ P + G P
Sbjct: 538 APAAGHDPDCAGCAPS-------PPATADQDDDSDGSTAASLAMEPLLGHGP------PV 584
Query: 488 NLSTGRQRSRSYDRSLQRSP--PVRLGSLERMLSCPVRLSEGPAAMAGPGSPPRRVTSFA 545
++ GR RSL R P P R S + P+ L+EG A A G +F
Sbjct: 585 DVPWGRG-DHYPRRSLARDPLCPSRSPSPS---AGPLSLAEGGAEDADWGVAAF-CPAFF 639
Query: 546 ELAKGRKKTGGSGSPPLRVSVGDSSQEFSPIQEAQQDR-----GAPLDEGTCCSHSLPPM 600
E G G SG+PPL ++ D +E + AQ+ A + G+ C S P+
Sbjct: 640 EDPLGTSPLGSSGAPPLPLTGEDELEEVGARRAAQRGHWRSNVSANNNSGSRCPESWDPV 699
Query: 601 PLGPGMDLLGPDPSPPWSTQVCQGPHSSEMPPAGLRATGQGPLAQLMDPG--PALPG--- 655
G + PSP + + P P GL+A A +PG P LP
Sbjct: 700 SAGGHAE---GCPSPKQTPRASPEPGYPGEPLLGLQA------ASAQEPGCCPGLPHLCS 750
Query: 656 ----SPANSHTQRDARARADGGGTESRPVLRYSKEQRPTTLPIQPFVFQHHFPKQLAKAR 711
+PA A GG + + + E TT P P
Sbjct: 751 AQGLAPAPCLVTPSWTETASSGGDHPQAEPKLATEAEGTTGPRLPLP------------- 797
Query: 712 ALHSLSQLYSLSGCSRTQQPAPLAAPAAQVSVP-APSGEPQASTPRATGR--------GA 762
S S +Q+ APL P+ + S P AP P + TP G
Sbjct: 798 -----------SVPSPSQEGAPL--PSEEASAPDAPDALPDSPTPATGGEVSAIKLASAL 844
Query: 763 RKAGSEPETSRPSPLGSYSPIRSVGPFGPSTDSSASTSCSPPPEQPTATESL 814
+ S PE PS + + G F TD+S+ + P+ A SL
Sbjct: 845 NGSSSSPEVEAPSSEDEDTAEATSGIF---TDTSSDGLQARRPDVVPAFRSL 893
Score = 40.0 bits (92), Expect = 0.017
Identities = 120/514 (23%), Positives = 170/514 (33%), Gaps = 87/514 (16%)
Query: 354 ASSPELDANCNSYRPHCEPCPAVADLTACFQSQAR---LVVATQNYYKLVTCDLSSQSSP 410
+SSPE++A + E + T+ QAR +V A ++ K V S S
Sbjct: 848 SSSPEVEAPSSEDEDTAEATSGIFTDTSSDGLQARRPDVVPAFRSLQKQVGTPDSLDSLD 907
Query: 411 SPAGSSITSCSEEHTKISPPPGPGPDPGPSQPSEYYL----FQKPE-VQPEEQEAVSSST 465
P+ S S+ ++ P GP G + + ++ PE V E QE
Sbjct: 908 IPS-----SASDGGYEVFSPSATGPSGGQPRALDSGYDTENYESPEFVLKEAQEGCEPQA 962
Query: 466 QAAAAVGPTVLEGQVYTNTSPPNLSTGRQRSRSYDRSLQRSPPVRLGSLERMLSCPVRLS 525
A A EG+ P T S S L P R + L +
Sbjct: 963 FAELAS-----EGE------GPGPETRLSTSLS---GLNEKNPYRDSAYFSDLEAEAEAT 1008
Query: 526 EGPAAMAGPGSPPRRVTSFAELAKGRKKTGG-SGSPPLRVSVGDSSQEFSP---IQEAQQ 581
GP G P EL G TG S LR V +Q P + Q
Sbjct: 1009 SGPEKKCGGDRAPG-----PEL--GLPSTGQPSEQVCLRPGVSGEAQGSGPGEVLPPLLQ 1061
Query: 582 DRGAPLDEGTCCSHSLPPMPLGPGMDLLGPDPSPPWS-----TQV---CQGPHSSEMPPA 633
G+ + TC S +P P G + P PSP S T V +G S P
Sbjct: 1062 LEGSSPEPSTCPSGLVPEPPEPQGPAKVRPGPSPSCSQFFLLTPVPLRSEGNSSEFQGPP 1121
Query: 634 GLRATGQGPLAQLMDPGP-------ALPGSPANSHTQRDARARADGGGTESRPVLRYSKE 686
GL +G P ++ PG ALPG PA + + ES LR
Sbjct: 1122 GL-LSGPAPQKRMGGPGTPRAPLRLALPGLPAALEGRPEEEEEDSEDSDESDEELRCYSV 1180
Query: 687 QRPT-----TLPIQPFVFQHHFPKQLAKARALHSLSQLYSLSGCSRTQQPAPLA------ 735
Q P+ P P V + R+L + L S + C ++
Sbjct: 1181 QEPSEDSEEEAPAVPVVVAE--SQSARNLRSLLKMPSLLSETFCEDLERKKKAVSFFDDV 1238
Query: 736 --------APAAQVSVPAPSGEPQASTPRATGRGARKAGSEPETSRPSPLGSYSPIRSVG 787
+P ++ P P + T G+ A + P+ + SP GS + G
Sbjct: 1239 TVYLFDQESPTRELGEPFPGAKESPPTFLRGSPGSPSAPNRPQQADGSPNGSTA--EEGG 1296
Query: 788 PFGPSTDSSASTS----------CSPPPEQPTAT 811
F D T+ +P P PT T
Sbjct: 1297 GFAWDDDFPLMTAKAAFAMALDPAAPAPAAPTPT 1330
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,664,801
Number of Sequences: 37866
Number of extensions: 4778272
Number of successful extensions: 35313
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 135
Number of HSP's successfully gapped in prelim test: 1105
Number of HSP's that attempted gapping in prelim test: 26727
Number of HSP's gapped (non-prelim): 8744
length of query: 1516
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1401
effective length of database: 13,892,928
effective search space: 19463992128
effective search space used: 19463992128
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.