SYK 12085

Name: SYK	Sequence: fasta or formatted (612aa)		NCBI GI: 205277435
Description: spleen tyrosine kinase isoform 2		Referenced in: Non-Receptor Tyrosine Kinase Pathways
Other entries for this name: alt prot [635aa] spleen tyrosine kinase isoform 1
Composition: Amino acid Percentage Count Longest homopolymer A alanine 7.2 44 2 C cysteine 1.5 9 1 D aspartate 4.4 27 1 E glutamate 7.8 48 2 F phenylalanine 2.9 18 3 G glycine 7.7 47 2 H histidine 2.9 18 2 I isoleucine 3.8 23 2 K lysine 7.5 46 2 L leucine 9.8 60 2 M methionine 3.1 19 1 N asparagine 4.9 30 2 P proline 5.1 31 1 Q glutamine 4.6 28 2 R arginine 4.7 29 1 S serine 5.6 34 2 T threonine 3.6 22 2 V valine 5.9 36 2 W tryptophan 1.6 10 1 Y tyrosine 5.4 33 3			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 spleen tyrosine kinase isoform 2 SYK 0.989 spleen tyrosine kinase isoform 1 ZAP70 0.544 zeta-chain associated protein kinase 70kDa isoform 1... ZAP70 0.290 zeta-chain associated protein kinase 70kDa isoform 2... ABL1 0.171 c-abl oncogene 1, receptor tyrosine kinase isoform a... ABL1 0.171 c-abl oncogene 1, receptor tyrosine kinase isoform b... ABL2 0.169 arg tyrosine kinase isoform c ABL2 0.169 arg tyrosine kinase isoform b ABL2 0.169 arg tyrosine kinase isoform e ABL2 0.169 arg tyrosine kinase isoform d ABL2 0.169 arg tyrosine kinase isoform a PTK2 0.152 PTK2 protein tyrosine kinase 2 isoform b PTK2 0.152 PTK2 protein tyrosine kinase 2 isoform a ERBB4 0.146 v-erb-a erythroblastic leukemia viral oncogene homo... ERBB4 0.146 v-erb-a erythroblastic leukemia viral oncogene homolo... EGFR 0.144 epidermal growth factor receptor isoform a precursor... LCK 0.142 lymphocyte-specific protein tyrosine kinase precurs... LCK 0.142 lymphocyte-specific protein tyrosine kinase precurs... HCK 0.142 hemopoietic cell kinase isoform p61HCK CSK 0.138 c-src tyrosine kinase CSK 0.138 c-src tyrosine kinase PTK2B 0.138 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... PTK2B 0.138 PTK2B protein tyrosine kinase 2 beta isoform b [Homo... PTK2B 0.138 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... PTK2B 0.138 PTK2B protein tyrosine kinase 2 beta isoform a [Homo... FRK 0.138 fyn-related kinase EPHB1 0.135 ephrin receptor EphB1 precursor TNK2 0.134 tyrosine kinase, non-receptor, 2 isoform 1 TNK2 0.134 tyrosine kinase, non-receptor, 2 isoform 2 ERBB2 0.134 erbB-2 isoform b Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.