Guide to the Human Genome
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Name: MATK Sequence: fasta or formatted (507aa) NCBI GI: 21450846
Description:

megakaryocyte-associated tyrosine kinase isoform a

Referenced in:

Platelets and Megakaryocytes
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [508aa] megakaryocyte-associated tyrosine kinase isoform b
alt prot [466aa] megakaryocyte-associated tyrosine kinase isoform c
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.1         46           2
 C cysteine            2.0         10           1
 D aspartate           3.7         19           1
 E glutamate           7.9         40           3
 F phenylalanine       3.4         17           2
 G glycine             7.9         40           1
 H histidine           3.9         20           2
 I isoleucine          2.2         11           1
 K lysine              6.3         32           2
 L leucine            10.8         55           2
 M methionine          2.4         12           1
 N asparagine          1.8          9           1
 P proline             5.7         29           3
 Q glutamine           3.4         17           2
 R arginine            7.3         37           2
 S serine              6.9         35           2
 T threonine           3.6         18           1
 V valine              7.9         40           2
 W tryptophan          2.0         10           1
 Y tyrosine            2.0         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   megakaryocyte-associated tyrosine kinase isoform a [... 
MATK                  0.950   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.914   megakaryocyte-associated tyrosine kinase isoform c [...
CSK                   0.454   c-src tyrosine kinase 
CSK                   0.454   c-src tyrosine kinase 
LCK                   0.255   lymphocyte-specific protein tyrosine kinase precurs...
LCK                   0.255   lymphocyte-specific protein tyrosine kinase precurs...
SRC                   0.246   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.246   proto-oncogene tyrosine-protein kinase SRC 
HCK                   0.244   hemopoietic cell kinase isoform p61HCK 
YES1                  0.241   viral oncogene yes-1 homolog 1 
FYN                   0.237   protein-tyrosine kinase fyn isoform a 
FER                   0.237   fer (fps/fes related) tyrosine kinase 
LYN                   0.236   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ...
LYN                   0.236   Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is...
ABL2                  0.234   arg tyrosine kinase isoform c 
ABL2                  0.234   arg tyrosine kinase isoform b 
ABL2                  0.234   arg tyrosine kinase isoform d 
ABL2                  0.234   arg tyrosine kinase isoform a 
BLK                   0.234   B lymphoid tyrosine kinase 
PTK6                  0.234   PTK6 protein tyrosine kinase 6 
ABL1                  0.232   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.232   c-abl oncogene 1, receptor tyrosine kinase isoform b...
FGR                   0.232   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.232   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.232   proto-oncogene tyrosine-protein kinase FGR 
ABL2                  0.231   arg tyrosine kinase isoform e 
FYN                   0.228   protein-tyrosine kinase fyn isoform b 
SRMS                  0.228   src-related kinase lacking C-terminal regulatory tyr...
FRK                   0.218   fyn-related kinase 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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