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Search of human proteins with 5454004
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5454004 D4, zinc and double PHD fingers family 2 [Homo
sapiens]
(391 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens] 829 0.0
gi|205830430 D4, zinc and double PHD fingers family 1 isoform a ... 476 e-134
gi|205830432 D4, zinc and double PHD fingers family 1 isoform b ... 407 e-114
gi|205830434 D4, zinc and double PHD fingers family 1 isoform c ... 396 e-110
gi|148762958 D4, zinc and double PHD fingers, family 3 [Homo sap... 378 e-105
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 136 4e-32
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 136 4e-32
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 136 4e-32
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 135 6e-32
gi|194328736 PHD finger protein 10 isoform b [Homo sapiens] 130 2e-30
gi|194328734 PHD finger protein 10 isoform a [Homo sapiens] 130 2e-30
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 91 1e-18
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 88 1e-17
gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [H... 65 8e-11
gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Ho... 65 8e-11
gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [H... 65 8e-11
gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [H... 64 3e-10
gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [H... 64 3e-10
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 63 4e-10
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 62 7e-10
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 62 1e-09
gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive ... 62 1e-09
gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo sa... 61 2e-09
gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo sa... 61 2e-09
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 60 3e-09
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 59 6e-09
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 58 2e-08
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 57 2e-08
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 56 6e-08
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 56 6e-08
>gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens]
Length = 391
Score = 829 bits (2141), Expect = 0.0
Identities = 391/391 (100%), Positives = 391/391 (100%)
Query: 1 MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKR 60
MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKR
Sbjct: 1 MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKR 60
Query: 61 HRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLE 120
HRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLE
Sbjct: 61 HRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLE 120
Query: 121 ALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRR 180
ALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRR
Sbjct: 121 ALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRR 180
Query: 181 GKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGED 240
GKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGED
Sbjct: 181 GKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGED 240
Query: 241 KEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGR 300
KEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGR
Sbjct: 241 KEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGR 300
Query: 301 SGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPS 360
SGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPS
Sbjct: 301 SGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPS 360
Query: 361 MSEPPEGSWSCHLCLDLLKEKASIYQNQNSS 391
MSEPPEGSWSCHLCLDLLKEKASIYQNQNSS
Sbjct: 361 MSEPPEGSWSCHLCLDLLKEKASIYQNQNSS 391
>gi|205830430 D4, zinc and double PHD fingers family 1 isoform a
[Homo sapiens]
Length = 414
Score = 476 bits (1225), Expect = e-134
Identities = 238/400 (59%), Positives = 283/400 (70%), Gaps = 32/400 (8%)
Query: 1 MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKR 60
MA V+ + L GE +Y++A+E C +YNARLCAERS+RLPFLDSQTGVAQ+NCYIWMEK
Sbjct: 28 MATVIPGPLSL-GEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKT 86
Query: 61 HRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLE 120
HRGPGLA GQ+Y+YPAR WRKKRR + EDPRL K D + LKKEG + + G LE
Sbjct: 87 HRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPE-GPVLE 145
Query: 121 ALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRR 180
ALL + EK+ L E ++++LE F DL+ ED E+D P+R+
Sbjct: 146 ALLCAETGEKK---------IELKEEETIMDCQKQQLLE---FPHDLEVEDLEDDIPRRK 193
Query: 181 GKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGED 240
+ K K G+G RK+ D + LEDRDKPY CDICGKRYKNRPGLSYHY H+HLAEEEGE+
Sbjct: 194 NRAKGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEEEGEE 253
Query: 241 ---------------KEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKK 285
K+ + V + + +KK PDG +PN YCDFCLG SK K
Sbjct: 254 NAERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSK---K 310
Query: 286 TGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFC 345
TG PE+L+SC+DCGRSGHPSCLQFT M AAV+TYRWQCIECK C++CGTSENDDQLLFC
Sbjct: 311 TGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQLLFC 370
Query: 346 DDCDRGYHMYCLTPSMSEPPEGSWSCHLCLDLLKEKASIY 385
DDCDRGYHMYCL+P M+EPPEGSWSCHLCL LKEKAS Y
Sbjct: 371 DDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAY 410
>gi|205830432 D4, zinc and double PHD fingers family 1 isoform b
[Homo sapiens]
Length = 380
Score = 407 bits (1047), Expect = e-114
Identities = 217/395 (54%), Positives = 259/395 (65%), Gaps = 56/395 (14%)
Query: 1 MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKR 60
MA V+ + L GE +Y++A+E C +YNARLCAERS+RLPFLDSQTGVAQ+NCYIWMEK
Sbjct: 28 MATVIPGPLSL-GEDFYREAIEHCRSYNARLCAERSLRLPFLDSQTGVAQNNCYIWMEKT 86
Query: 61 HRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLE 120
HRGPGLA GQ+Y+YPAR WRKKRR + EDPRL K D + LKKEG + + G LE
Sbjct: 87 HRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPE-GPVLE 145
Query: 121 ALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRR 180
ALL + EK+ L E ++++LE F DL+ ED E+D P+R+
Sbjct: 146 ALLCAETGEKK---------IELKEEETIMDCQKQQLLE---FPHDLEVEDLEDDIPRRK 193
Query: 181 GKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGED 240
+ K K G+G RK+ D + LEDRDKPY CD K YK +
Sbjct: 194 NRAKGKAYGIGGLRKRQDTASLEDRDKPYVCD---KFYKELAWV---------------- 234
Query: 241 KEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGR 300
P +QR + +KK PDG +PN YCDFCLG SK KTG PE+L+SC+DCGR
Sbjct: 235 --------PEAQR--KHTAKKAPDGTVIPNGYCDFCLGGSK---KTGCPEDLISCADCGR 281
Query: 301 SGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSEND----------DQLLFCDDCDR 350
SGHPSCLQFT M AAV+TYRWQCIECK C++CGTSEND DQLLFCDDCDR
Sbjct: 282 SGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDGASWAGLTPQDQLLFCDDCDR 341
Query: 351 GYHMYCLTPSMSEPPEGSWSCHLCLDLLKEKASIY 385
GYHMYCL+P M+EPPEGSWSCHLCL LKEKAS Y
Sbjct: 342 GYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAY 376
>gi|205830434 D4, zinc and double PHD fingers family 1 isoform c
[Homo sapiens]
Length = 332
Score = 396 bits (1017), Expect = e-110
Identities = 200/344 (58%), Positives = 236/344 (68%), Gaps = 31/344 (9%)
Query: 57 MEKRHRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDG 116
MEK HRGPGLA GQ+Y+YPAR WRKKRR + EDPRL K D + LKKEG + + G
Sbjct: 1 MEKTHRGPGLAPGQIYTYPARCWRKKRRLNILEDPRLRPCEYKIDCEAPLKKEGGLPE-G 59
Query: 117 SSLEALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDT 176
LEALL + EK+ L E ++++LE F DL+ ED E+D
Sbjct: 60 PVLEALLCAETGEKK---------IELKEEETIMDCQKQQLLE---FPHDLEVEDLEDDI 107
Query: 177 PKRRGKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEE 236
P+R+ + K K G+G RK+ D + LEDRDKPY CDICGKRYKNRPGLSYHY H+HLAEE
Sbjct: 108 PRRKNRAKGKAYGIGGLRKRQDTASLEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEE 167
Query: 237 EGED---------------KEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSK 281
EGE+ K+ + V + + +KK PDG +PN YCDFCLG SK
Sbjct: 168 EGEENAERHALPFHRKNNHKQFYKELAWVPEAQRKHTAKKAPDGTVIPNGYCDFCLGGSK 227
Query: 282 INKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQ 341
KTG PE+L+SC+DCGRSGHPSCLQFT M AAV+TYRWQCIECK C++CGTSENDDQ
Sbjct: 228 ---KTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQ 284
Query: 342 LLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCLDLLKEKASIY 385
LLFCDDCDRGYHMYCL+P M+EPPEGSWSCHLCL LKEKAS Y
Sbjct: 285 LLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCLRHLKEKASAY 328
>gi|148762958 D4, zinc and double PHD fingers, family 3 [Homo
sapiens]
Length = 357
Score = 378 bits (970), Expect = e-105
Identities = 178/304 (58%), Positives = 233/304 (76%), Gaps = 13/304 (4%)
Query: 1 MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKR 60
MA V+ N +K LG+Q+YK+A+E C +YN+RLCAERSVRLPFLDSQTGVAQ+NCYIWMEKR
Sbjct: 1 MATVIHNPLKALGDQFYKEAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKR 60
Query: 61 HRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLE 120
HRGPGLA GQLY+YPAR WRKKRR HPPEDP+L IKP+ + LKK+G S+ ++LE
Sbjct: 61 HRGPGLAPGQLYTYPARCWRKKRRLHPPEDPKLRLLEIKPEVELPLKKDGFTSES-TTLE 119
Query: 121 ALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDD-LDDEDYEEDTPKR 179
ALLR + +EK+ D R +++S+ E +R+LE D+ +++ ++ED EED PKR
Sbjct: 120 ALLRGEGVEKK--VDAR-EEESIQEI--------QRVLENDENVEEGNEEEDLEEDIPKR 168
Query: 180 RGKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGE 239
+ + + + +G R++ DA+ ED DKPY CDICGKRYKNRPGLSYHYAH+HLA EEG+
Sbjct: 169 KNRTRGRARGSAGGRRRHDAASQEDHDKPYVCDICGKRYKNRPGLSYHYAHTHLASEEGD 228
Query: 240 DKEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCG 299
+ +D + +P + R+E + +KGPDG +PNNYCDFCLG S +NKK+G+PEELVSC+DCG
Sbjct: 229 EAQDQETRSPPNHRNENHRPQKGPDGTVIPNNYCDFCLGGSNMNKKSGRPEELVSCADCG 288
Query: 300 RSGH 303
RS H
Sbjct: 289 RSAH 292
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 136 bits (342), Expect = 4e-32
Identities = 57/110 (51%), Positives = 75/110 (68%), Gaps = 2/110 (1%)
Query: 266 LALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCI 325
+A P C FCLG + N++ +PEEL+SC+DCG SGHPSCL+F+P + VK RWQCI
Sbjct: 202 VAEPIPICSFCLGTKEQNREK-KPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCI 260
Query: 326 ECKCCNIC-GTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
ECK C+ C +N D +LFCD CDRG+HM C P ++ P+G W C +C
Sbjct: 261 ECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQIC 310
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 136 bits (342), Expect = 4e-32
Identities = 57/110 (51%), Positives = 75/110 (68%), Gaps = 2/110 (1%)
Query: 266 LALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCI 325
+A P C FCLG + N++ +PEEL+SC+DCG SGHPSCL+F+P + VK RWQCI
Sbjct: 202 VAEPIPICSFCLGTKEQNREK-KPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCI 260
Query: 326 ECKCCNIC-GTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
ECK C+ C +N D +LFCD CDRG+HM C P ++ P+G W C +C
Sbjct: 261 ECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQIC 310
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 136 bits (342), Expect = 4e-32
Identities = 57/110 (51%), Positives = 75/110 (68%), Gaps = 2/110 (1%)
Query: 266 LALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCI 325
+A P C FCLG + N++ +PEEL+SC+DCG SGHPSCL+F+P + VK RWQCI
Sbjct: 202 VAEPIPICSFCLGTKEQNREK-KPEELISCADCGNSGHPSCLKFSPELTVRVKALRWQCI 260
Query: 326 ECKCCNIC-GTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
ECK C+ C +N D +LFCD CDRG+HM C P ++ P+G W C +C
Sbjct: 261 ECKTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPPLTRMPKGMWICQIC 310
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 135 bits (340), Expect = 6e-32
Identities = 67/147 (45%), Positives = 85/147 (57%), Gaps = 15/147 (10%)
Query: 244 SQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGH 303
S PP + ++Q A P C FCLG + N++ +PEEL+SC+DCG SGH
Sbjct: 194 SLPPVSLLPHEKDQPR-------ADPIPICSFCLGTKESNREK-KPEELLSCADCGSSGH 245
Query: 304 PSCLQFTPVMMAAVKTYRWQCIECKCCNICGT-SENDDQLLFCDDCDRGYHMYCLTPSMS 362
PSCL+F P + VK RWQCIECK C+ C N D +LFCD CDRG+HM C P +S
Sbjct: 246 PSCLKFCPELTTNVKALRWQCIECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLS 305
Query: 363 EPPEGSWSCHLC------LDLLKEKAS 383
P+G W C +C LL EKA+
Sbjct: 306 RMPKGMWICQVCRPKKKGRKLLHEKAA 332
>gi|194328736 PHD finger protein 10 isoform b [Homo sapiens]
Length = 496
Score = 130 bits (327), Expect = 2e-30
Identities = 78/238 (32%), Positives = 113/238 (47%), Gaps = 27/238 (11%)
Query: 137 RVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRRGKGKSKGKGVGSARKK 196
R D L P+ N+ + L+P+ L LD + +D RG K K KG +
Sbjct: 266 RYSPDELRYLPL-NTALYEPPLDPE--LPALDSDGDSDDGEDGRGDEKRKNKGTSDSSS- 321
Query: 197 LDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSQPPTPVSQRSEE 256
++ E P + + S ++ +DK + P +RS
Sbjct: 322 --GNVSEGESPPDSQE-----------------DSFQGRQKSKDKA-ATPRKDGPKRSVL 361
Query: 257 QKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAA 316
KS G +PN C CL + NKK G+ E L+ CS C SGHPSCL T +++
Sbjct: 362 SKSVPGYKPKVIPNAICGICLKGKESNKK-GKAESLIHCSQCENSGHPSCLDMTMELVSM 420
Query: 317 VKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
+KTY WQC+ECK C ICG ++++++FCD CDRGYH +C+ + P G W C C
Sbjct: 421 IKTYPWQCMECKTCIICGQPHHEEEMMFCDMCDRGYHTFCV--GLGAIPSGRWICDCC 476
>gi|194328734 PHD finger protein 10 isoform a [Homo sapiens]
Length = 498
Score = 130 bits (327), Expect = 2e-30
Identities = 78/238 (32%), Positives = 113/238 (47%), Gaps = 27/238 (11%)
Query: 137 RVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRRGKGKSKGKGVGSARKK 196
R D L P+ N+ + L+P+ L LD + +D RG K K KG +
Sbjct: 268 RYSPDELRYLPL-NTALYEPPLDPE--LPALDSDGDSDDGEDGRGDEKRKNKGTSDSSS- 323
Query: 197 LDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSQPPTPVSQRSEE 256
++ E P + + S ++ +DK + P +RS
Sbjct: 324 --GNVSEGESPPDSQE-----------------DSFQGRQKSKDKA-ATPRKDGPKRSVL 363
Query: 257 QKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAA 316
KS G +PN C CL + NKK G+ E L+ CS C SGHPSCL T +++
Sbjct: 364 SKSVPGYKPKVIPNAICGICLKGKESNKK-GKAESLIHCSQCENSGHPSCLDMTMELVSM 422
Query: 317 VKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
+KTY WQC+ECK C ICG ++++++FCD CDRGYH +C+ + P G W C C
Sbjct: 423 IKTYPWQCMECKTCIICGQPHHEEEMMFCDMCDRGYHTFCV--GLGAIPSGRWICDCC 478
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 91.3 bits (225), Expect = 1e-18
Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 39/205 (19%)
Query: 178 KRRGKGKSKG-KGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEE 236
+RR +G + G +G G AR K AS +E DI S ++E
Sbjct: 1311 RRRPRGGAHGGRGRGRARLKSTASSIETL---VVADI----------------DSSPSKE 1351
Query: 237 EGEDKEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCS 296
E E+ +D+ T V + D L + C C + G L++CS
Sbjct: 1352 EEEEDDDTMQNTVVLFSNT--------DKFVLMQDMCVVCGSFGR-----GAEGHLLACS 1398
Query: 297 DCGRSGHPSCL--QFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHM 354
C + HP C+ + T VM+ W+C+EC C +CG + + +LL CDDCD YH
Sbjct: 1399 QCSQCYHPYCVNSKITKVMLLK----GWRCVECIVCEVCGQASDPSRLLLCDDCDISYHT 1454
Query: 355 YCLTPSMSEPPEGSWSCHLCLDLLK 379
YCL P + P+G W C C+ ++
Sbjct: 1455 YCLDPPLLTVPKGGWKCKWCVSCMQ 1479
Score = 86.3 bits (212), Expect = 4e-17
Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 287 GQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCD 346
G+ +L C+ CG H +CL + A K WQC ECK C C ND ++L C+
Sbjct: 236 GELCDLFFCTSCGHHYHGACLD---TALTARKRAGWQCPECKVCQACRKPGNDSKMLVCE 292
Query: 347 DCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
CD+GYH +CL P M E P SW C C
Sbjct: 293 TCDKGYHTFCLKPPMEELPAHSWKCKAC 320
Score = 36.6 bits (83), Expect = 0.040
Identities = 14/51 (27%), Positives = 24/51 (47%), Gaps = 3/51 (5%)
Query: 284 KKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICG 334
+K G +++ C C + H CL+ M + + W+C C+ C CG
Sbjct: 280 RKPGNDSKMLVCETCDKGYHTFCLK---PPMEELPAHSWKCKACRVCRACG 327
Score = 33.5 bits (75), Expect = 0.34
Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 1/49 (2%)
Query: 326 ECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
E +C G E D L FC C YH CL +++ W C C
Sbjct: 226 EARCAVCEGPGELCD-LFFCTSCGHHYHGACLDTALTARKRAGWQCPEC 273
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 88.2 bits (217), Expect = 1e-17
Identities = 35/89 (39%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query: 287 GQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCD 346
G L++CS CG+ HP C+ + V + W+C+EC C CG + + +LL CD
Sbjct: 969 GAEGRLLACSQCGQCYHPYCVSIK--ITKVVLSKGWRCLECTVCEACGKATDPGRLLLCD 1026
Query: 347 DCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
DCD YH YCL P + P+G W C C+
Sbjct: 1027 DCDISYHTYCLDPPLQTVPKGGWKCKWCV 1055
Score = 81.3 bits (199), Expect = 1e-15
Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 295 CSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHM 354
C+ CG+ H CL + + +K WQC ECK C C S D ++L CD CD+GYH
Sbjct: 359 CTTCGQHYHGMCLD---IAVTPLKRAGWQCPECKVCQNCKQSGEDSKMLVCDTCDKGYHT 415
Query: 355 YCLTPSMSEPPEGSWSCHLC 374
+CL P M P W C C
Sbjct: 416 FCLQPVMKSVPTNGWKCKNC 435
Score = 48.5 bits (114), Expect = 1e-05
Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 6/68 (8%)
Query: 284 KKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGT---SENDD 340
K++G+ +++ C C + H CLQ PVM + V T W+C C+ C CGT S+
Sbjct: 395 KQSGEDSKMLVCDTCDKGYHTFCLQ--PVMKS-VPTNGWKCKNCRICIECGTRSSSQWHH 451
Query: 341 QLLFCDDC 348
L CD+C
Sbjct: 452 NCLICDNC 459
Score = 37.7 bits (86), Expect = 0.018
Identities = 30/125 (24%), Positives = 39/125 (31%), Gaps = 38/125 (30%)
Query: 285 KTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTS-------- 336
K P L+ C DC S H CL P + K W+C C C CG +
Sbjct: 1015 KATDPGRLLLCDDCDISYHTYCLD--PPLQTVPKG-GWKCKWCVWCRHCGATSAGLRCEW 1071
Query: 337 -----------------------ENDDQLLFCDDCDRGYHMYCLTPSMSEPPEG----SW 369
+D +L C CDR H C + E E +
Sbjct: 1072 QNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGF 1131
Query: 370 SCHLC 374
C +C
Sbjct: 1132 DCSMC 1136
Score = 31.2 bits (69), Expect = 1.7
Identities = 12/45 (26%), Positives = 19/45 (42%)
Query: 330 CNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
C +C + + FC C + YH CL +++ W C C
Sbjct: 344 CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQCPEC 388
>gi|226443002 jumonji, AT rich interactive domain 1D isoform 3 [Homo
sapiens]
Length = 1482
Score = 65.5 bits (158), Expect = 8e-11
Identities = 24/53 (45%), Positives = 32/53 (60%)
Query: 323 QCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
Q I+ C +C + DD+LLFCD CD YH++CL P + E P G W C C+
Sbjct: 253 QFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 305
>gi|33356560 jumonji, AT rich interactive domain 1D isoform 2 [Homo
sapiens]
Length = 1539
Score = 65.5 bits (158), Expect = 8e-11
Identities = 24/53 (45%), Positives = 32/53 (60%)
Query: 323 QCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
Q I+ C +C + DD+LLFCD CD YH++CL P + E P G W C C+
Sbjct: 310 QFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
>gi|226442991 jumonji, AT rich interactive domain 1D isoform 1 [Homo
sapiens]
Length = 1570
Score = 65.5 bits (158), Expect = 8e-11
Identities = 24/53 (45%), Positives = 32/53 (60%)
Query: 323 QCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
Q I+ C +C + DD+LLFCD CD YH++CL P + E P G W C C+
Sbjct: 310 QFIDSYICQVCSRGDEDDKLLFCDGCDDNYHIFCLLPPLPEIPRGIWRCPKCI 362
>gi|226442963 jumonji, AT rich interactive domain 1C isoform 2 [Homo
sapiens]
Length = 1379
Score = 63.5 bits (153), Expect = 3e-10
Identities = 24/53 (45%), Positives = 32/53 (60%)
Query: 323 QCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
Q IE C +C + DD+LL CD CD YH++CL P + E P+G W C C+
Sbjct: 253 QFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCV 305
>gi|109255243 jumonji, AT rich interactive domain 1C isoform 1 [Homo
sapiens]
Length = 1560
Score = 63.5 bits (153), Expect = 3e-10
Identities = 24/53 (45%), Positives = 32/53 (60%)
Query: 323 QCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
Q IE C +C + DD+LL CD CD YH++CL P + E P+G W C C+
Sbjct: 320 QFIESYVCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCV 372
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 63.2 bits (152), Expect = 4e-10
Identities = 24/46 (52%), Positives = 29/46 (63%)
Query: 330 CNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
C +C +ND+ LL CD CDRG H+YC P M PEG W C +CL
Sbjct: 1679 CLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFCTVCL 1724
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 62.4 bits (150), Expect = 7e-10
Identities = 23/45 (51%), Positives = 28/45 (62%)
Query: 330 CNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
C +CG S+ +D+LL CD CD GYHM CL P + E P W C C
Sbjct: 186 CEVCGRSDREDRLLLCDGCDAGYHMECLDPPLQEVPVDEWFCPEC 230
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 61.6 bits (148), Expect = 1e-09
Identities = 21/51 (41%), Positives = 32/51 (62%)
Query: 325 IECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
++ C +CG+ ++D+LL CD CD YH +CL P + + P+G W C CL
Sbjct: 307 VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCL 357
>gi|169218173 PREDICTED: similar to Jumonji, AT rich interactive
domain 1B (RBP2-like), partial [Homo sapiens]
Length = 977
Score = 61.6 bits (148), Expect = 1e-09
Identities = 21/51 (41%), Positives = 32/51 (62%)
Query: 325 IECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
++ C +CG+ ++D+LL CD CD YH +CL P + + P+G W C CL
Sbjct: 307 VDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCL 357
>gi|110618244 retinoblastoma binding protein 2 isoform 1 [Homo
sapiens]
Length = 1690
Score = 61.2 bits (147), Expect = 2e-09
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 325 IECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
++ C CG N+D+LL CD CD YH +CL P + + P+G W C C+
Sbjct: 291 VDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCV 341
>gi|110618242 retinoblastoma binding protein 2 isoform 2 [Homo
sapiens]
Length = 1641
Score = 61.2 bits (147), Expect = 2e-09
Identities = 21/51 (41%), Positives = 30/51 (58%)
Query: 325 IECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
++ C CG N+D+LL CD CD YH +CL P + + P+G W C C+
Sbjct: 291 VDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDWRCPKCV 341
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 60.1 bits (144), Expect = 3e-09
Identities = 18/45 (40%), Positives = 30/45 (66%)
Query: 330 CNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
C +C DD+L+ CD+C++ +H++CL P++ E P+G W C C
Sbjct: 1187 CKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPAC 1231
Score = 33.5 bits (75), Expect = 0.34
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 281 KINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECK 328
K+ +K G+ ++L+ C +C ++ H CL+ + V WQC C+
Sbjct: 1188 KVCRKKGEDDKLILCDECNKAFHLFCLR---PALYEVPDGEWQCPACQ 1232
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 59.3 bits (142), Expect = 6e-09
Identities = 63/240 (26%), Positives = 93/240 (38%), Gaps = 53/240 (22%)
Query: 174 EDTPKRRGKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHL 233
+ P R+ K K +GKG G RKK+ S + + K G +++ + S
Sbjct: 235 QPVPIRKAKTK-EGKGPG-VRKKIKGS-KDGKKKGKGKKTAGLKFRFGGISNKRKKGSSS 291
Query: 234 AEEEGEDKE-DSQPPTPVSQRSE-----------EQKSKKGPDGLALPNNYCDFCLGDSK 281
E+E E+ + DS S RSE +K K+ DG ++ D+C
Sbjct: 292 EEDEREESDFDSASIHSASVRSECSAALGKKSKRRRKKKRIDDGDGYETDHQDYC----- 346
Query: 282 INKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNI--------- 332
+ Q E++ C C R+ H CL P + A + +W C C+ I
Sbjct: 347 --EVCQQGGEIILCDTCPRAYHLVCLD--PELEKAPEG-KWSCPHCEKEGIQWEPKDDDD 401
Query: 333 ------CGTSENDDQLLF------------CDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
C E DD + F CD C YH++CL P + E P G W C C
Sbjct: 402 EEEEGGC-EEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRC 460
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 57.8 bits (138), Expect = 2e-08
Identities = 60/255 (23%), Positives = 92/255 (36%), Gaps = 70/255 (27%)
Query: 175 DTPKRRGKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLA 234
+ P R+ K K +GKG + RK + + D KP + + K G S
Sbjct: 254 EVPIRKAKTK-EGKGPNARRKPKGSPRVPDAKKPKPKKVAPLKIK-LGGFGSKRKRSSSE 311
Query: 235 EEEGEDKED-----------SQPPTPVSQRSEEQ-----KSKKGPDGLALPN-------N 271
+++ + + D S T S RS ++ K KKG + + + +
Sbjct: 312 DDDLDVESDFDDASINSYSVSDGSTSRSSRSRKKLRTTKKKKKGEEEVTAVDGYETDHQD 371
Query: 272 YCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCN 331
YC+ C Q E++ C C R+ H CL P M A + +W C C+
Sbjct: 372 YCEVCQ----------QGGEIILCDTCPRAYHMVCLD--PDMEKAPEG-KWSCPHCEKEG 418
Query: 332 I--------------------------------CGTSENDDQLLFCDDCDRGYHMYCLTP 359
I C ++ +LL CD C YH++CL P
Sbjct: 419 IQWEAKEDNSEGEEILEEVGGDLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNP 478
Query: 360 SMSEPPEGSWSCHLC 374
+ E P G W C C
Sbjct: 479 PLPEIPNGEWLCPRC 493
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 57.4 bits (137), Expect = 2e-08
Identities = 20/46 (43%), Positives = 28/46 (60%)
Query: 330 CNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
C IC +N++ LL CD CD+G H YC P ++ P+G W C C+
Sbjct: 1934 CQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACI 1979
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 55.8 bits (133), Expect = 6e-08
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Query: 327 CKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
CK C G +EN ++ CD CDRG+H YC+ P + PEG W C C
Sbjct: 1119 CKICRKKGDAEN---MVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPEC 1163
Score = 32.3 bits (72), Expect = 0.75
Identities = 16/48 (33%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 281 KINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECK 328
KI +K G E +V C C R H C++ + V W C EC+
Sbjct: 1120 KICRKKGDAENMVLCDGCDRGHHTYCVR---PKLKTVPEGDWFCPECR 1164
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 55.8 bits (133), Expect = 6e-08
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Query: 327 CKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLC 374
CK C G +EN ++ CD CDRG+H YC+ P + PEG W C C
Sbjct: 1151 CKICRKKGDAEN---MVLCDGCDRGHHTYCVRPKLKTVPEGDWFCPEC 1195
Score = 32.3 bits (72), Expect = 0.75
Identities = 16/48 (33%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 281 KINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECK 328
KI +K G E +V C C R H C++ + V W C EC+
Sbjct: 1152 KICRKKGDAENMVLCDGCDRGHHTYCVR---PKLKTVPEGDWFCPECR 1196
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,838,541
Number of Sequences: 37866
Number of extensions: 1024089
Number of successful extensions: 13750
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 598
Number of HSP's successfully gapped in prelim test: 339
Number of HSP's that attempted gapping in prelim test: 5875
Number of HSP's gapped (non-prelim): 6374
length of query: 391
length of database: 18,247,518
effective HSP length: 104
effective length of query: 287
effective length of database: 14,309,454
effective search space: 4106813298
effective search space used: 4106813298
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.