BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A [Homo sapiens] (249 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 500 e-142 gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens] 388 e-108 gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 347 7e-96 gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 298 4e-81 gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear... 270 7e-73 gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear... 270 7e-73 gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 241 6e-64 gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens] 232 3e-61 gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens] 206 2e-53 gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 191 5e-49 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 76 2e-14 gi|60498973 myelin transcription factor 1-like [Homo sapiens] 70 1e-12 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 70 2e-12 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 70 2e-12 gi|21735415 centromere protein B [Homo sapiens] 66 2e-11 gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 65 6e-11 gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 65 7e-11 gi|87298937 centrosomal protein 110kDa [Homo sapiens] 65 7e-11 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 65 7e-11 gi|55956788 nucleolin [Homo sapiens] 64 2e-10 gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 62 4e-10 gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 62 4e-10 gi|17975763 myelin transcription factor 1 [Homo sapiens] 62 4e-10 gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 4e-10 gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 4e-10 gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 4e-10 gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 4e-10 gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 4e-10 gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 4e-10 gi|11545835 TSPY-like 2 [Homo sapiens] 62 4e-10 >gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A [Homo sapiens] Length = 249 Score = 500 bits (1288), Expect = e-142 Identities = 249/249 (100%), Positives = 249/249 (100%) Query: 1 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL Sbjct: 1 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60 Query: 61 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL Sbjct: 61 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120 Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD 180 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD Sbjct: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD 180 Query: 181 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKRE 240 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKRE Sbjct: 181 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKRE 240 Query: 241 PEDEGEDDD 249 PEDEGEDDD Sbjct: 241 PEDEGEDDD 249 >gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens] Length = 234 Score = 388 bits (997), Expect = e-108 Identities = 205/238 (86%), Positives = 212/238 (89%), Gaps = 4/238 (1%) Query: 1 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60 MEMGRRIH ELRNR PSDVKEL LDNSRSNEGKLE LTDEFEELEFLS IN GLTSI++L Sbjct: 1 MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60 Query: 61 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120 PKL KL+KLEL RVSGGLEVLAEKCPNLTHL LSGNKIKDLSTIEPLK+LENLKSLDL Sbjct: 61 PKL-KLRKLEL---RVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116 Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD 180 FNCEVTNLNDY ENVFKLL QLTYLD D KEAP SD E +VEGLDDEEE E EEEYD Sbjct: 117 FNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYD 176 Query: 181 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRK 238 EDAQVVEDEE E+EEEEGEEEDVSG +EEDEEGYNDGEVD EEDEEELGEEERGQKRK Sbjct: 177 EDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234 >gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 251 Score = 347 bits (889), Expect = 7e-96 Identities = 178/254 (70%), Positives = 216/254 (85%), Gaps = 9/254 (3%) Query: 1 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60 M+M RRIHLELRNRTP+ V+ELVLDN +SN+GK+EGLT EF LEFLS INVGL S++NL Sbjct: 1 MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNL 60 Query: 61 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120 PKL KLKKLELS+NR+ GGL++LAEK PNLTHLNLSGNK+KD+ST+EPLKKLE LKSLDL Sbjct: 61 PKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDL 120 Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDE----DE 176 FNCEVTNLNDYRE+VFKLLPQLTYLDGYDR+D+EAPDSDAE V+G+D+EEEDE +E Sbjct: 121 FNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAE--VDGVDEEEEDEEGEDEE 178 Query: 177 EEYDEDAQVVE--DEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERG 234 +E DED + E +E+DEDE+ EG+E+D EEE+E G ++ + D++EDEEE E +G Sbjct: 179 DEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEE-EEGGKG 237 Query: 235 QKRKREPEDEGEDD 248 +KRKRE +DEGEDD Sbjct: 238 EKRKRETDDEGEDD 251 >gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 1 [Homo sapiens] Length = 268 Score = 298 bits (762), Expect = 4e-81 Identities = 158/267 (59%), Positives = 204/267 (76%), Gaps = 18/267 (6%) Query: 1 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60 MEM ++I+LELRNR+P +V ELVLDN G++EGL D F+ELEFLS NV L+S+A L Sbjct: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60 Query: 61 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120 P LNKL+KLELSDN +SGGLEVLAEKCPNLT+LNLSGNKIKDLST+E L+ L+NLKSLDL Sbjct: 61 PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120 Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY 179 FNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E +G DDEEE+E+E Sbjct: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180 Query: 180 DEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEEDEE---ELGE 230 E + E+EE+E++E+E E+ED +G E E+E G + E+ DEED++ E GE Sbjct: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240 Query: 231 EE--------RGQKRKREPEDEGEDDD 249 EE RG+KRKR+ ED+GE++D Sbjct: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267 >gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 272 Score = 270 bits (691), Expect = 7e-73 Identities = 143/233 (61%), Positives = 178/233 (76%), Gaps = 9/233 (3%) Query: 19 VKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSG 78 V+E VLDN +SN+ K+E LT EF LEFL INVGL SI+NLPKL KLKK LS+NR+ G Sbjct: 39 VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98 Query: 79 GLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKL 138 GL + AEK PNLTHLNLSG K+KD+ST+EPLKKLE LKSLDLFNCEV NLNDY+E+VFKL Sbjct: 99 GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158 Query: 139 LPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDE------DEEEYDEDAQVVEDEEDE 192 LPQLT LD YD +D+EAPDSDA+ V+G+D EEEDE D E D + + +++EEDE Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ--VDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDE 216 Query: 193 DEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEE-RGQKRKREPEDE 244 DE+ EG+++ EEE+E G + E D++EDE+E EE +G+ RKRE +DE Sbjct: 217 DEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDE 269 >gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 272 Score = 270 bits (691), Expect = 7e-73 Identities = 143/233 (61%), Positives = 178/233 (76%), Gaps = 9/233 (3%) Query: 19 VKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSG 78 V+E VLDN +SN+ K+E LT EF LEFL INVGL SI+NLPKL KLKK LS+NR+ G Sbjct: 39 VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98 Query: 79 GLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKL 138 GL + AEK PNLTHLNLSG K+KD+ST+EPLKKLE LKSLDLFNCEV NLNDY+E+VFKL Sbjct: 99 GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158 Query: 139 LPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDE------DEEEYDEDAQVVEDEEDE 192 LPQLT LD YD +D+EAPDSDA+ V+G+D EEEDE D E D + + +++EEDE Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ--VDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDE 216 Query: 193 DEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEE-RGQKRKREPEDE 244 DE+ EG+++ EEE+E G + E D++EDE+E EE +G+ RKRE +DE Sbjct: 217 DEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDE 269 >gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 3 [Homo sapiens] Length = 220 Score = 241 bits (614), Expect = 6e-64 Identities = 128/217 (58%), Positives = 166/217 (76%), Gaps = 18/217 (8%) Query: 51 NVGLTSIANLPKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLK 110 NV L+S+A LP LNKL+KLELSDN +SGGLEVLAEKCPNLT+LNLSGNKIKDLST+E L+ Sbjct: 3 NVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQ 62 Query: 111 KLENLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDD 169 L+NLKSLDLFNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E +G DD Sbjct: 63 NLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDD 122 Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEE 223 EEE+E+E E + E+EE+E++E+E E+ED +G E E+E G + E+ DEE Sbjct: 123 EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 182 Query: 224 DEE---ELGEEE--------RGQKRKREPEDEGEDDD 249 D++ E GEEE RG+KRKR+ ED+GE++D Sbjct: 183 DDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 219 >gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens] Length = 131 Score = 232 bits (591), Expect = 3e-61 Identities = 117/131 (89%), Positives = 123/131 (93%) Query: 1 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60 MEMG+ IHLELRNRTPSDVKEL LDNS+SNEGKLEGLTDEFEELE L+TIN+GLTSIANL Sbjct: 1 MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60 Query: 61 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120 PKLNKLKKLELS NR S GLEVLAEKCPNL HLNLSGNKIKDLSTIEPLKKLENL+SLDL Sbjct: 61 PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120 Query: 121 FNCEVTNLNDY 131 F CEVTNLN+Y Sbjct: 121 FTCEVTNLNNY 131 >gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens] Length = 450 Score = 206 bits (524), Expect = 2e-53 Identities = 104/143 (72%), Positives = 120/143 (83%) Query: 19 VKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSG 78 V+E VLDN +SN+ K+E LT EF LEFL INVGL SI+NLPKL KLKK LS+NR+ G Sbjct: 39 VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98 Query: 79 GLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKL 138 GL + AEK PNLTHLNLSG K+KD+ST+EPLKKLE LKSLDLFNCEV NLNDY+E+VFKL Sbjct: 99 GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158 Query: 139 LPQLTYLDGYDRDDKEAPDSDAE 161 LPQLT LD YD +D+EAPDSDA+ Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ 181 >gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E isoform 2 [Homo sapiens] Length = 227 Score = 191 bits (485), Expect = 5e-49 Identities = 119/267 (44%), Positives = 165/267 (61%), Gaps = 59/267 (22%) Query: 1 MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60 MEM ++I+LELRNR+P +V ELVLDN G++EGL D F+ELEFLS NV Sbjct: 1 MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANV-------- 52 Query: 61 PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120 +L+ L +L P+L NK++ + L+NLKSLDL Sbjct: 53 -ELSSLARL------------------PSL-------NKLRK-------QNLKNLKSLDL 79 Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY 179 FNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E +G DDEEE+E+E Sbjct: 80 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 139 Query: 180 DEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEEDEE---ELGE 230 E + E+EE+E++E+E E+ED +G E E+E G + E+ DEED++ E GE Sbjct: 140 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 199 Query: 231 EE--------RGQKRKREPEDEGEDDD 249 EE RG+KRKR+ ED+GE++D Sbjct: 200 EEEEEEEGGLRGEKRKRDAEDDGEEED 226 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 76.3 bits (186), Expect = 2e-14 Identities = 47/98 (47%), Positives = 61/98 (62%), Gaps = 3/98 (3%) Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE-EEEGE-EEDVSGEEEEDE 211 E + + EG EG + EE E E E +E E+EE E+E EEEGE EE+ GE EE+E Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017 Query: 212 EGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 EG +GEV+ EE E E GEEE G++ E E EGE ++ Sbjct: 1018 EGEVEGEVEGEEGEGE-GEEEEGEEEGEEREKEGEGEE 1054 Score = 68.6 bits (166), Expect = 5e-12 Identities = 45/109 (41%), Positives = 60/109 (55%), Gaps = 10/109 (9%) Query: 150 RDDKEAPDSDAEGYVE-GLDDEEEDEDEEEYDEDAQVVEDEEDEDEEE------EGEEED 202 + ++E + + EG E G +EEE E EEE E E EE E EEE EGEEE+ Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882 Query: 203 VSGEEEEDEEG---YNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248 GE EE+ EG +GE + EE+ E GEEE G+ + E +EGE + Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE 931 Score = 68.6 bits (166), Expect = 5e-12 Identities = 42/106 (39%), Positives = 59/106 (55%), Gaps = 7/106 (6%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE---E 207 ++ E + EG EG ++E E E EEE + + + E E + +EE EGE E+ GE E Sbjct: 863 EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE 922 Query: 208 EEDEEGYNDGEVD----DEEDEEELGEEERGQKRKREPEDEGEDDD 249 EE EEG +GE + + ED E GEEE G+ E E EGE ++ Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968 Score = 68.6 bits (166), Expect = 5e-12 Identities = 42/105 (40%), Positives = 59/105 (56%), Gaps = 5/105 (4%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGE--EEDV 203 +G ++ E + EG +G ++ EE E E E +E ED E E EEEEGE E+ Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960 Query: 204 SGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248 GE E +EEG +GE + E EEE GE G+ + E E+EGE++ Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGE---GEGEEEEGEEEGEEE 1002 Score = 68.2 bits (165), Expect = 7e-12 Identities = 40/105 (38%), Positives = 59/105 (56%), Gaps = 1/105 (0%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEE-DVS 204 +G + +E + + EG + EE+E+E E +E+ E+EE E EEEEGE + + Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEE 861 Query: 205 GEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 GEE E EE +GE + EE+E E EE G+ E E EGE ++ Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE 906 Score = 68.2 bits (165), Expect = 7e-12 Identities = 42/106 (39%), Positives = 61/106 (57%), Gaps = 2/106 (1%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205 +G ++E + + E EG +EEE E E E + + + E+E + EEEGEE + G Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932 Query: 206 EEEEDEEGYNDGEVDDEEDEEEL-GEEERGQ-KRKREPEDEGEDDD 249 EEEE E DGE + EE+E E GEEE G+ + + E E EGE+ + Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE 978 Score = 67.4 bits (163), Expect = 1e-11 Identities = 41/93 (44%), Positives = 55/93 (59%), Gaps = 5/93 (5%) Query: 161 EGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE----EDEEGYND 216 E EG +E+E+ E E E + + E+E+EE EGEEE+ GEEE E+EEG Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857 Query: 217 GEVDDEEDE-EELGEEERGQKRKREPEDEGEDD 248 GE + EE E EE GEE G+ + E E EGE++ Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEE 890 Score = 67.0 bits (162), Expect = 1e-11 Identities = 46/117 (39%), Positives = 64/117 (54%), Gaps = 16/117 (13%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEED-----EDEEEYDEDAQVVEDEEDEDEEEEGE---E 200 + ++ E + + EG E + EEE+ E+E E E + E+ E E EEEEGE E Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGE 888 Query: 201 EDVSGEEEEDE---EGYNDGEVDDEEDE-----EELGEEERGQKRKREPEDEGEDDD 249 E+ GE EE+E EG +GE + EE+E EE GEE G+ + E E EGED + Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGE 945 Score = 65.9 bits (159), Expect = 3e-11 Identities = 41/106 (38%), Positives = 61/106 (57%), Gaps = 7/106 (6%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEE-EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEE 209 ++ E + EG EG D E E E+EE E++ + + E E +E+ E EGEE + GEEEE Sbjct: 926 EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985 Query: 210 ------DEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 +EEG +GE + E +EE GE E ++ + E E EGE+ + Sbjct: 986 GEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031 Score = 65.5 bits (158), Expect = 4e-11 Identities = 42/112 (37%), Positives = 61/112 (54%), Gaps = 13/112 (11%) Query: 151 DDKEAPDSDAEGYVEGLDDE-----EEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205 D +E + + EG EG +E E++E E + +E A E E+E ++ EGEEE+ G Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803 Query: 206 EEEEDEEG--YNDGEVD------DEEDEEELGEEERGQKRKREPEDEGEDDD 249 EE EEG GEV+ +EE+EE GEEE G+ + E E E E+ + Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE 855 Score = 65.1 bits (157), Expect = 6e-11 Identities = 40/106 (37%), Positives = 61/106 (57%), Gaps = 5/106 (4%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEE--EGEEEDV 203 +G +++ + + EG EG ++E E + EEE +E E+EE E E E EGE E+ Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951 Query: 204 SGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 GE E +EE +GE + EE+ E GEE G+ + E E EGE+++ Sbjct: 952 EGEWEGEEE---EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEE 994 Score = 63.9 bits (154), Expect = 1e-10 Identities = 42/111 (37%), Positives = 62/111 (55%), Gaps = 7/111 (6%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDE---EDEDEEEEGEEED 202 +G +++ + + EG EG ++E E E EEE + + + E E E+E EE EGE E+ Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934 Query: 203 VSGEEE-EDEEGYND---GEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 GE E ED EG + GE + EE+E E EE G+ E E EGE+++ Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985 Score = 63.5 bits (153), Expect = 2e-10 Identities = 43/101 (42%), Positives = 58/101 (57%), Gaps = 7/101 (6%) Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE-EEEDEE 212 E + + EG EG ++E E E+EE E+ + E+E EE EGEEE GE E E+EE Sbjct: 825 EREEEEEEG--EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882 Query: 213 GYNDGEVDDE-EDEEELGE---EERGQKRKREPEDEGEDDD 249 G +GE + E E EEE GE EE G+ E E EG+ ++ Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923 Score = 62.8 bits (151), Expect = 3e-10 Identities = 42/97 (43%), Positives = 53/97 (54%), Gaps = 4/97 (4%) Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDE-EDEDEEEEGEEEDVSGEEEEDEE 212 E + EG EG +E E E EEE E E E E E+EE EGE E+ E E+EE Sbjct: 859 EEEGEEGEGEEEG--EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916 Query: 213 GYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 G GE + EE E E GEEE G+ + E EGE+++ Sbjct: 917 GEGKGEEEGEEGEGE-GEEEEGEGEGEDGEGEGEEEE 952 Score = 62.8 bits (151), Expect = 3e-10 Identities = 44/105 (41%), Positives = 61/105 (58%), Gaps = 4/105 (3%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEED-EDEEEYDEDAQVVEDEEDEDE-EEEGEEEDV 203 +G + ++E + + EG E + E ED E E E +E E+EE E E EEEGE E Sbjct: 916 EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE 975 Query: 204 SGE-EEEDEEGYNDGEVDD-EEDEEELGEEERGQKRKREPEDEGE 246 GE E E+EEG +GE ++ EE+ EE GE E + + E E+EGE Sbjct: 976 EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020 Score = 58.2 bits (139), Expect = 7e-09 Identities = 41/108 (37%), Positives = 62/108 (57%), Gaps = 16/108 (14%) Query: 157 DSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGE--EEDVSGEEEEDEEGY 214 + EG E D EEE+E E E E+ + E+ E E E+EEGE +E+ +G+EE+ EE Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEG-EEVEGEREKEEGERKKEERAGKEEKGEEEG 791 Query: 215 NDGEVDDEEDE------EELG-------EEERGQKRKREPEDEGEDDD 249 + GE ++EE E EE G EE +G++ + E E EGE+++ Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839 Score = 57.4 bits (137), Expect = 1e-08 Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 7/102 (6%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDE-EDEDEEEEGEEEDVS 204 +G + + +E + + EG EG E E E+EEE + + +V +E E E EEEEGEEE Sbjct: 989 EGEEEEGEEEGEEEGEGEEEG---EGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE--- 1042 Query: 205 GEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGE 246 GEE E E + + EE+EEE G+ + + + E +D E Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084 Score = 57.0 bits (136), Expect = 1e-08 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 4/105 (3%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE-EEEGEEEDVS 204 DG +++ KE + + +++ E+E E +E+ E+EE E E +EEGE E+V Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE 765 Query: 205 GEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 GE E++E + + ++ +EE GEEE Q E E EG ++ Sbjct: 766 GEREKEE---GERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807 Score = 56.6 bits (135), Expect = 2e-08 Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 5/96 (5%) Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEG 213 E + + EG EG + EEE E E E +E+ +V + E E+ E EGEEE+ EEE EE Sbjct: 991 EEEEGEEEGEEEG-EGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE---GEEEGEER 1046 Query: 214 YNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 +GE ++ E EEE G K + E+E E D Sbjct: 1047 EKEGEGEENRRNREEEEEEEG-KYQETGEEENERQD 1081 Score = 56.2 bits (134), Expect = 3e-08 Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 9/108 (8%) Query: 150 RDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEE 209 R + E P + E + ++ D +E+E E Q + E +++ EE GEEE GEEEE Sbjct: 683 RGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE 742 Query: 210 DE---------EGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248 + EG +GE ++ E E E E ER ++ + E++GE++ Sbjct: 743 GDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790 Score = 56.2 bits (134), Expect = 3e-08 Identities = 41/116 (35%), Positives = 60/116 (51%), Gaps = 20/116 (17%) Query: 152 DKEAPDSDAEGYVEGLDDEEEDEDEEEYDE-------DAQVVEDEEDEDE---------- 194 ++E + E + EG ++EE D +EEE E + + VE E +++E Sbjct: 724 NQEMEEGGEEEHGEG-EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAG 782 Query: 195 -EEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 EE+GEEE GE EE EE GE +E E E GE E G+ + E E+EGE ++ Sbjct: 783 KEEKGEEEGDQGEGEE-EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEE 837 Score = 55.8 bits (133), Expect = 3e-08 Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%) Query: 153 KEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEE 212 KE EG E + EE+E + E +E+ + EE E EE EGE E GE +++E Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780 Query: 213 GYNDGEVDDEEDEEELGEEERGQKRKREPEDEGE 246 + + ++E D+ E GEEE + R E E+ GE Sbjct: 781 AGKEEKGEEEGDQGE-GEEEETEGRGEEKEEGGE 813 Score = 48.9 bits (115), Expect = 4e-06 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 8/95 (8%) Query: 151 DDKEAPDSDAEGYVEGLDDE---EEDEDEEEYDEDAQVVEDEE-----DEDEEEEGEEED 202 + +E + + EG VEG + E EE+E EEE +E + E EE +E+EEEEG+ ++ Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071 Query: 203 VSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKR 237 EE E ++G +V + + G+ + QK+ Sbjct: 1072 TGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKK 1106 Score = 45.4 bits (106), Expect = 5e-05 Identities = 25/88 (28%), Positives = 49/88 (55%), Gaps = 3/88 (3%) Query: 165 EGLDDEEEDEDEEEYDEDAQVVEDEE---DEDEEEEGEEEDVSGEEEEDEEGYNDGEVDD 221 +G D+ E E + + ++ E EE + EE+E +E + ++E ++E GE + Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEH 735 Query: 222 EEDEEELGEEERGQKRKREPEDEGEDDD 249 E EEE G+ E ++++ E ++EGE ++ Sbjct: 736 GEGEEEEGDREEEEEKEGEGKEEGEGEE 763 Score = 42.7 bits (99), Expect = 3e-04 Identities = 31/102 (30%), Positives = 55/102 (53%), Gaps = 3/102 (2%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 ++ +K+ + E EG + E E+ ++ D + Q ++ E ++E +E + GEE Sbjct: 675 EKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEE- 733 Query: 209 EDEEGYNDGEVDDEEDEEELGE-EERGQKRKREPEDEGEDDD 249 E EG + E D EE+EE+ GE +E G+ + E E E E+ + Sbjct: 734 EHGEG-EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGE 774 Score = 42.4 bits (98), Expect = 4e-04 Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 4/95 (4%) Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEG 213 E S AE + + ++ E+ E ++ E + E E++ E+EE ++ D GEE+E +E Sbjct: 660 EEGSSGAEHWQD--EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRD--GEEQEQKER 715 Query: 214 YNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248 + + ++ EE GEEE G+ + E + E E++ Sbjct: 716 EQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEE 750 Score = 33.5 bits (75), Expect = 0.18 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 39/122 (31%) Query: 164 VEGLDDEEEDEDEEE---YDEDAQVVEDEEDEDEEE------------------------ 196 +E DEE + EE+ D +E++E E EE Sbjct: 576 IEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAE 635 Query: 197 --EGEEEDVSGEEEEDEEGYNDGEVDD--------EEDEEELGEEERGQKRKREPEDEGE 246 EG+ + V GE E+ EG DG ++ +++E E GE+++G+ P EGE Sbjct: 636 VSEGKAKSV-GEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERP-GEGE 693 Query: 247 DD 248 + Sbjct: 694 KE 695 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 70.5 bits (171), Expect = 1e-12 Identities = 46/95 (48%), Positives = 59/95 (62%), Gaps = 14/95 (14%) Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEG 213 E DSD E +D++EEDE EEY ED DE++EDEE + EEE+ EE+ED++ Sbjct: 89 ECDDSDG---TEDMDEKEEDEG-EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD- 143 Query: 214 YNDGE-VDDEEDEEELGEEERGQKRKREPEDEGED 247 DGE V+DEE+EEE EEE E E+E ED Sbjct: 144 -EDGEDVEDEEEEEEEEEEE-------EEEEENED 170 Score = 63.9 bits (154), Expect = 1e-10 Identities = 38/101 (37%), Positives = 60/101 (59%), Gaps = 9/101 (8%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 D D+KE + + E Y E +DE DEDEE+ + D + E+ E+EDE+++ + EDV EEE Sbjct: 98 DMDEKE--EDEGEEYSED-NDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEE 154 Query: 209 EDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 E+E E ++EE+EEE + + R +D +DD+ Sbjct: 155 EEE------EEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189 Score = 60.1 bits (144), Expect = 2e-09 Identities = 34/88 (38%), Positives = 54/88 (61%), Gaps = 6/88 (6%) Query: 164 VEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEG--EEEDVSGEEEEDEEGYNDGEVDD 221 V+ DD + ED +E +ED +E ED +E G +EED G+ EE+EE + E DD Sbjct: 87 VDECDDSDGTEDMDEKEEDEG---EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE-DD 142 Query: 222 EEDEEELGEEERGQKRKREPEDEGEDDD 249 +ED E++ +EE ++ + E E+E E++D Sbjct: 143 DEDGEDVEDEEEEEEEEEEEEEEEENED 170 Score = 58.9 bits (141), Expect = 4e-09 Identities = 37/86 (43%), Positives = 47/86 (54%), Gaps = 9/86 (10%) Query: 148 YDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEE 207 Y D+ E D D E E D EEE+E EEE ++D + ED EDE+EEEE EEE+ EE Sbjct: 110 YSEDNDEPGDEDEED--EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167 Query: 208 EEDEEG-------YNDGEVDDEEDEE 226 ED + D E DD ++E Sbjct: 168 NEDHQMNCHNTRIMQDTEKDDNNNDE 193 Score = 43.1 bits (100), Expect = 2e-04 Identities = 19/66 (28%), Positives = 39/66 (59%) Query: 182 DAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREP 241 D+ V++ +D D E+ +E++ EE E+ G+ D+E++E + EEE ++ + Sbjct: 83 DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142 Query: 242 EDEGED 247 +++GED Sbjct: 143 DEDGED 148 Score = 43.1 bits (100), Expect = 2e-04 Identities = 21/80 (26%), Positives = 43/80 (53%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 D +D+E + E E +D++ED ++ E +E+ + E+EE+E+EE E + + Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180 Query: 209 EDEEGYNDGEVDDEEDEEEL 228 + +D D+ ++ +EL Sbjct: 181 MQDTEKDDNNNDEYDNYDEL 200 Score = 40.0 bits (92), Expect = 0.002 Identities = 20/79 (25%), Positives = 46/79 (58%), Gaps = 5/79 (6%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205 +G +++E + D + +G D E+E+E+EEE +E E+EE+E+E+ + + Sbjct: 126 EGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE-----EEEEEENEDHQMNCHNTRI 180 Query: 206 EEEEDEEGYNDGEVDDEED 224 ++ +++ N+ E D+ ++ Sbjct: 181 MQDTEKDDNNNDEYDNYDE 199 Score = 33.9 bits (76), Expect = 0.14 Identities = 20/104 (19%), Positives = 47/104 (45%), Gaps = 7/104 (6%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205 DG D +D+E + + E +EEE+E+ E++ + +D ++++ +E + Sbjct: 145 DGEDVEDEEEEEEEEE-------EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNY 197 Query: 206 EEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 +E + N G++ ++ E E ED+ + ++ Sbjct: 198 DELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 70.1 bits (170), Expect = 2e-12 Identities = 39/99 (39%), Positives = 56/99 (56%), Gaps = 6/99 (6%) Query: 156 PDSDAEGYVEGLDD------EEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEE 209 P+ + + GLDD +EE E E +V E+ E+E+EEEE EEED EEEE Sbjct: 492 PEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEE 551 Query: 210 DEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248 +EEG ++G DEEDE+ E++ G+ ++P E D Sbjct: 552 EEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSD 590 Score = 56.2 bits (134), Expect = 3e-08 Identities = 42/113 (37%), Positives = 58/113 (51%), Gaps = 23/113 (20%) Query: 151 DDKEAPDSDAEGY-VEGL----------DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGE 199 DD EA SD E VEG ++EEE+E+EEE DE+++ E+EE E E EG+ Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD 563 Query: 200 EEDVSGEEEED----------EEGYNDGEVDDEEDEEELGEEERGQKRKREPE 242 EED +E+D +E +D E D ++D + EE K KR E Sbjct: 564 EEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK--EERAYDKAKRRIE 614 Score = 44.7 bits (104), Expect = 8e-05 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 10/90 (11%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEE---DVSGEEEEDEEGYN-------DGEV 219 E ++ E +E VE EE+ED E+ G ++ S EE E EG + E Sbjct: 474 EVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEE 533 Query: 220 DDEEDEEELGEEERGQKRKREPEDEGEDDD 249 ++EE+EEE +EE ++ + E E EG + D Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGD 563 Score = 43.9 bits (102), Expect = 1e-04 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Query: 169 DEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEEL 228 + EE+ED E+ D ++E E+ EG + + +E +EE + E +++E+ EE Sbjct: 491 EPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE- 549 Query: 229 GEEERGQKRKREPEDEGE 246 EEE G+ E ++E E Sbjct: 550 EEEEEGESEGSEGDEEDE 567 Score = 38.9 bits (89), Expect = 0.004 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%) Query: 149 DRDDKEAPDSD------AEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEED 202 D D +E D D A+ VE ++D+D + + A+ + ++ + E+ED Sbjct: 110 DNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDED 169 Query: 203 VSGEEEEDEEGYNDGEVDDEEDE--EELGEEERGQKRKREP--EDEGEDDD 249 S + +E + GE DE DE + +++ QK K P E EDDD Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDD 220 Score = 37.0 bits (84), Expect = 0.016 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 23/100 (23%) Query: 172 EDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEE--GYNDGEV---------- 219 E ++ E E VE E E+E V EEEED E G +D E Sbjct: 459 ESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKV 518 Query: 220 -----------DDEEDEEELGEEERGQKRKREPEDEGEDD 248 + EE+EEE EEE ++ + E E+EGE + Sbjct: 519 EGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESE 558 Score = 36.2 bits (82), Expect = 0.027 Identities = 23/106 (21%), Positives = 51/106 (48%), Gaps = 10/106 (9%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +K+ D D + ++ L++ + + D + V+ E+ +EE +++ G+ Sbjct: 42 GKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQ 101 Query: 207 EEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDE---GEDDD 249 + + + D+ D EEL +++ K+ +P+ E G DDD Sbjct: 102 KGKKQSF-------DDNDSEELEDKDSKSKKTAKPKVEMYSGSDDD 140 Score = 35.4 bits (80), Expect = 0.047 Identities = 23/107 (21%), Positives = 53/107 (49%), Gaps = 16/107 (14%) Query: 156 PDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEG----------------E 199 P S+ + +++ + D+++ D+ + E EE E E+++G + Sbjct: 293 PASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK 352 Query: 200 EEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGE 246 EE+ + EE+E E++ + EEE E+E+ +++K++ ++ E Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKE 399 Score = 35.0 bits (79), Expect = 0.061 Identities = 24/109 (22%), Positives = 47/109 (43%), Gaps = 17/109 (15%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 ++++ E D E EE+ + + D V+ E++ E E+D G+++ Sbjct: 255 EKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314 Query: 209 EDEEGYNDGEVDDEEDEEELG-----------------EEERGQKRKRE 240 + ++ GE +++E E++ G EEE QKR+ E Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363 Score = 30.8 bits (68), Expect = 1.2 Identities = 18/84 (21%), Positives = 47/84 (55%), Gaps = 4/84 (4%) Query: 168 DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEE--EEDEEGYNDGEVDDEEDE 225 ++EEE +++ + + + D+++ EE E++D ++ + E Y+ DD++D Sbjct: 86 NNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGS--DDDDDF 143 Query: 226 EELGEEERGQKRKREPEDEGEDDD 249 +L ++ +G+ +K + +G ++D Sbjct: 144 NKLPKKAKGKAQKSNKKWDGSEED 167 Score = 30.8 bits (68), Expect = 1.2 Identities = 22/102 (21%), Positives = 51/102 (50%), Gaps = 23/102 (22%) Query: 155 APDSDAEGYVEGLDDEEEDEDEEEYDEDAQ--------------VVEDEEDEDEEEEGEE 200 A + D EG + D +++ ++EE +++ + + + +E+E+ ++ EE Sbjct: 304 AAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363 Query: 201 EDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPE 242 E + EE + + ++EE L +E+R +K+++E E Sbjct: 364 ERIKRLEELEAK---------RKEEERLEQEKRERKKQKEKE 396 Score = 28.9 bits (63), Expect = 4.4 Identities = 41/198 (20%), Positives = 81/198 (40%), Gaps = 23/198 (11%) Query: 63 LNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFN 122 L +L++L L + E +A K N ++ ++ + KK + K + Sbjct: 59 LKELEELSLEAQGIKADRETVAVKPTE--------NNEEEFTSKDKKKKGQKGKKQSFDD 110 Query: 123 CEVTNLNDYRENVFKLL-PQLTYLDGYDRDDK-----EAPDSDAEGYVEGLDDEEEDEDE 176 + L D K P++ G D DD + A+ + D EEDED Sbjct: 111 NDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN 170 Query: 177 -EEYDEDAQVVEDEEDEDEEEE------GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELG 229 ++ E +++ E DE +E G++++ + + E N E DD + + Sbjct: 171 SKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGN--EDDDASFKIKTV 228 Query: 230 EEERGQKRKREPEDEGED 247 +++ +K++RE + E+ Sbjct: 229 AQKKAEKKERERKKRDEE 246 Score = 28.5 bits (62), Expect = 5.7 Identities = 21/101 (20%), Positives = 47/101 (46%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 D D +A ++ EG + E + ++ E + DE+D +E E + G + Sbjct: 15 DDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKA 74 Query: 209 EDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 + E ++EE+ ++++GQK K++ D+ + ++ Sbjct: 75 DRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115 Score = 28.5 bits (62), Expect = 5.7 Identities = 37/163 (22%), Positives = 71/163 (43%), Gaps = 22/163 (13%) Query: 20 KELVLDNSRSN---EGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRV 76 K +LD R +G+ G+T + + NV L +I K+ +K + + R+ Sbjct: 644 KTKILDKLRHTHVQDGEAGGITQQ------IGATNVPLEAINEQTKM--IKNFDRENVRI 695 Query: 77 SGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVF 136 G L + + ++L G+ + D++ + ++ + L+ E NL ++ Sbjct: 696 PGMLIIDTPGHESFSNLRNRGSSLCDIAILV----VDIMHGLEPQTIESINLLKSKK--- 748 Query: 137 KLLPQLTYLDGYDR--DDKEAPDSDAEGYVEGLDDEEEDEDEE 177 P + L+ DR D K++PDSD ++ +DE EE Sbjct: 749 --CPFIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEE 789 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 69.7 bits (169), Expect = 2e-12 Identities = 37/81 (45%), Positives = 52/81 (64%), Gaps = 11/81 (13%) Query: 169 DEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEEL 228 DEEE+E+EE EE+E+EEEE EEED EEE++EE + + E ++EE EEE Sbjct: 887 DEEEEEEEE-----------EEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF 935 Query: 229 GEEERGQKRKREPEDEGEDDD 249 EEE + + E EDE E+++ Sbjct: 936 EEEEGELEEEEEEEDEEEEEE 956 Score = 66.2 bits (160), Expect = 2e-11 Identities = 41/92 (44%), Positives = 57/92 (61%), Gaps = 9/92 (9%) Query: 142 LTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE-EEEGEE 200 LT ++ D++E + + E E ++EEED +EEE DE+ E+EE+E+E EEE EE Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937 Query: 201 EDVSGEEEEDEEGYNDGEVDDEEDEEELGEEE 232 E+ EEEE+EE DEE+EEEL E E Sbjct: 938 EEGELEEEEEEE--------DEEEEEELEEVE 961 Score = 55.5 bits (132), Expect = 4e-08 Identities = 30/73 (41%), Positives = 47/73 (64%), Gaps = 4/73 (5%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 + +D E + D E Y E ++EEE+ +EE +E+ ++ E+EE+EDEEEE E E+V E Sbjct: 906 EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV----E 961 Query: 209 EDEEGYNDGEVDD 221 + E G GEV++ Sbjct: 962 DLEFGTAGGEVEE 974 >gi|21735415 centromere protein B [Homo sapiens] Length = 599 Score = 66.2 bits (160), Expect = 2e-11 Identities = 31/66 (46%), Positives = 47/66 (71%) Query: 165 EGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEED 224 EG ++EEE+E+EEE + + + E+E +E+EEE GE E++ EEE +EEG D + ++EED Sbjct: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463 Query: 225 EEELGE 230 EE E Sbjct: 464 EESSSE 469 Score = 64.3 bits (155), Expect = 9e-11 Identities = 36/76 (47%), Positives = 49/76 (64%), Gaps = 6/76 (7%) Query: 168 DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEE 227 ++EEE+E+EEE +E E+EE E+EEEEG E + GEEEE EE +G+VD +E+EE Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE---EGDVDSDEEEE- 461 Query: 228 LGEEERGQKRKREPED 243 E+E E ED Sbjct: 462 --EDEESSSEGLEAED 475 Score = 53.9 bits (128), Expect = 1e-07 Identities = 30/66 (45%), Positives = 44/66 (66%), Gaps = 5/66 (7%) Query: 186 VEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEE--DEEELGEEERGQKRKREPED 243 ++ E +E+EEEE EEE+ GE EE+EE +GE ++EE + EELGEEE ++ D Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEGEEEEE---EGEEEEEEGGEGEELGEEEEVEEEGDVDSD 457 Query: 244 EGEDDD 249 E E++D Sbjct: 458 EEEEED 463 Score = 53.5 bits (127), Expect = 2e-07 Identities = 31/78 (39%), Positives = 48/78 (61%), Gaps = 11/78 (14%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEE-EGEEEDVSGEEEEDEEGYNDGEVDDEEDEEEL 228 + E E+EEE +EE+E+EEE EGEEE+ GEEEE+E G + E+ +EE+ EE Sbjct: 402 KSEGEEEEE---------EEEEEEEEEGEGEEEEEEGEEEEEEGGEGE-ELGEEEEVEEE 451 Query: 229 GEEERGQKRKREPEDEGE 246 G+ + ++ + + E E Sbjct: 452 GDVDSDEEEEEDEESSSE 469 Score = 52.0 bits (123), Expect = 5e-07 Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 41/137 (29%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEED---------EDEEE 196 +G + +++E + + EG EG ++EEE E+EEE + + + +EE+ ++EEE Sbjct: 404 EGEEEEEEEEEEEEEEG--EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461 Query: 197 EGEEEDVSGEEEED------------------EEG------YNDGEVDDEEDEEELGEEE 232 E EE G E ED EE + +G D + D EE +EE Sbjct: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521 Query: 233 RGQKRKREPEDEGEDDD 249 + EDE +DDD Sbjct: 522 ------EDDEDEDDDDD 532 Score = 49.7 bits (117), Expect = 2e-06 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 49/131 (37%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDED---------EEEYDEDAQVVEDEEDEDEEE--- 196 + +++E + + EG E + EEE+E+ EEE +E+ V DEE+E++EE Sbjct: 409 EEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSS 468 Query: 197 ------------------------------------EGEEEDVSGEEEEDEEGYNDGEVD 220 EG E+ S EEED+E +D + D Sbjct: 469 EGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDED 528 Query: 221 DEEDEEELGEE 231 D++DEE+ G+E Sbjct: 529 DDDDEED-GDE 538 Score = 40.4 bits (93), Expect = 0.001 Identities = 18/41 (43%), Positives = 29/41 (70%), Gaps = 2/41 (4%) Query: 163 YVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDV 203 ++EG E+ D D EE D++ + EDE+D+D+EE+G+E V Sbjct: 503 FLEG--GEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPV 541 Score = 31.6 bits (70), Expect = 0.67 Identities = 15/46 (32%), Positives = 28/46 (60%), Gaps = 3/46 (6%) Query: 140 PQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQV 185 P L +L+G + D ++ + D E E D++E+D+D+EE ++ V Sbjct: 499 PTLHFLEGGEDSDSDSEEEDDE---EEDDEDEDDDDDEEDGDEVPV 541 >gi|31621309 leucine rich repeat containing 6 [Homo sapiens] Length = 466 Score = 65.1 bits (157), Expect = 6e-11 Identities = 61/216 (28%), Positives = 100/216 (46%), Gaps = 23/216 (10%) Query: 33 KLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSGGLEVLAEKCPNLTH 92 +LE + +L+ L N + I N+ KL KL+ L L+ N + +E L E C L Sbjct: 35 RLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEK-IENL-EGCEELAK 92 Query: 93 LNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDD 152 L+L+ N I +LS+I+ L+ +LK L L + + YRE V LPQL +LDG + + Sbjct: 93 LDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEP 152 Query: 153 KEAPDSDAEGYVEGLDDEEEDED----EEEYDEDAQVVEDEEDEDEEEEGEE-------- 200 E + + V E+++D + E+AQ EED++E++ Sbjct: 153 SERIKALQDYSVIEPQIREQEKDHCLKRAKLKEEAQRKHQEEDKNEDKRSNAGFDGRWYT 212 Query: 201 ---------EDVSGEEEEDEEGYNDGEVDDEEDEEE 227 E + D E +N ++D+ ED+ E Sbjct: 213 DINATLSSLESKDHLQAPDTEEHNTKKLDNSEDDLE 248 >gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] Length = 709 Score = 64.7 bits (156), Expect = 7e-11 Identities = 41/99 (41%), Positives = 56/99 (56%), Gaps = 9/99 (9%) Query: 152 DKEAPDSDAEGYVEGLDDEEEDEDE-EEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + E SD E G DE+ + E EE + V EDEE E++ EE EE D GEEEE+ Sbjct: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234 Query: 211 EEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 EE +EE+EEE EEE ++ +R+ ++EG D D Sbjct: 235 EE--------EEEEEEEEEEEEEYEQDERDQKEEGNDYD 265 Score = 54.3 bits (129), Expect = 1e-07 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 8/86 (9%) Query: 171 EEDEDEEEYDEDAQVV------EDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDD--E 222 +E+ + EEY D + E + + EEEG EEDV +EE +E+ D EVD+ E Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230 Query: 223 EDEEELGEEERGQKRKREPEDEGEDD 248 E+EEE EEE ++ + E ++ E D Sbjct: 231 EEEEEEEEEEEEEEEEEEEYEQDERD 256 Score = 50.1 bits (118), Expect = 2e-06 Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 4/81 (4%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 +++E + D E E +D EEDE+ +E E+ + E+EE+E+EEEE EEE E ++ Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE-EEEYEQDERDQK 258 Query: 211 EEGYNDGEVDDEEDEEELGEE 231 EEG + D + + G E Sbjct: 259 EEG---NDYDTRSEASDSGSE 276 Score = 50.1 bits (118), Expect = 2e-06 Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 9/98 (9%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEE----DEDEEEEGEEEDVS 204 D ++ E + DAE E +D EE+E+EEE +E+ + E+EE + D++EEG + D Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTR 267 Query: 205 GEEEE---DEEGYNDGEVDDEEDEEELGEEERGQKRKR 239 E + + + DG V + G +E+ ++RKR Sbjct: 268 SEASDSGSESVSFTDGSVRSGSGTD--GSDEKKKERKR 303 Score = 41.6 bits (96), Expect = 7e-04 Identities = 27/119 (22%), Positives = 52/119 (43%), Gaps = 5/119 (4%) Query: 136 FKLLPQLTYLDGYDRDDK-EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE 194 +K P+ T + D + + ++P D + D + E+ E D + Sbjct: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHET 185 Query: 195 EEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEER----GQKRKREPEDEGEDDD 249 G ++ E +EEG + +DEE EE+ E+E G++ + E E+E E+++ Sbjct: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244 >gi|87298937 centrosomal protein 110kDa [Homo sapiens] Length = 2325 Score = 64.7 bits (156), Expect = 7e-11 Identities = 66/232 (28%), Positives = 113/232 (48%), Gaps = 7/232 (3%) Query: 19 VKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSG 78 VK VL+ S + GK+E L D+ +L L+ ++ I + + L+KL L+ N + Sbjct: 125 VKLEVLNLSYNLIGKIEKL-DKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEH 183 Query: 79 GLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKL 138 L +K +L LNL GNKI L I LK L++L SL L V L Y + Sbjct: 184 IPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFH 243 Query: 139 LPQLTYLDGY---DRDDKEAPDSDAEGYVEGLDDEEED---EDEEEYDEDAQVVEDEEDE 192 L L L+G +D +EA + + VE L+ + E E EE + + +E+ +++ Sbjct: 244 LRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQ 303 Query: 193 DEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDE 244 D+ + +E+ +++ EE +D +E +++ E R +++ E E E Sbjct: 304 DKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQE 355 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 64.7 bits (156), Expect = 7e-11 Identities = 41/99 (41%), Positives = 56/99 (56%), Gaps = 9/99 (9%) Query: 152 DKEAPDSDAEGYVEGLDDEEEDEDE-EEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + E SD E G DE+ + E EE + V EDEE E++ EE EE D GEEEE+ Sbjct: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234 Query: 211 EEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 EE +EE+EEE EEE ++ +R+ ++EG D D Sbjct: 235 EE--------EEEEEEEEEEEEEYEQDERDQKEEGNDYD 265 Score = 54.3 bits (129), Expect = 1e-07 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 8/86 (9%) Query: 171 EEDEDEEEYDEDAQVV------EDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDD--E 222 +E+ + EEY D + E + + EEEG EEDV +EE +E+ D EVD+ E Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230 Query: 223 EDEEELGEEERGQKRKREPEDEGEDD 248 E+EEE EEE ++ + E ++ E D Sbjct: 231 EEEEEEEEEEEEEEEEEEEYEQDERD 256 Score = 50.1 bits (118), Expect = 2e-06 Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 4/81 (4%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 +++E + D E E +D EEDE+ +E E+ + E+EE+E+EEEE EEE E ++ Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE-EEEYEQDERDQK 258 Query: 211 EEGYNDGEVDDEEDEEELGEE 231 EEG + D + + G E Sbjct: 259 EEG---NDYDTRSEASDSGSE 276 Score = 50.1 bits (118), Expect = 2e-06 Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 9/98 (9%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEE----DEDEEEEGEEEDVS 204 D ++ E + DAE E +D EE+E+EEE +E+ + E+EE + D++EEG + D Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTR 267 Query: 205 GEEEE---DEEGYNDGEVDDEEDEEELGEEERGQKRKR 239 E + + + DG V + G +E+ ++RKR Sbjct: 268 SEASDSGSESVSFTDGSVRSGSGTD--GSDEKKKERKR 303 Score = 41.6 bits (96), Expect = 7e-04 Identities = 27/119 (22%), Positives = 52/119 (43%), Gaps = 5/119 (4%) Query: 136 FKLLPQLTYLDGYDRDDK-EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE 194 +K P+ T + D + + ++P D + D + E+ E D + Sbjct: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHET 185 Query: 195 EEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEER----GQKRKREPEDEGEDDD 249 G ++ E +EEG + +DEE EE+ E+E G++ + E E+E E+++ Sbjct: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 63.5 bits (153), Expect = 2e-10 Identities = 40/113 (35%), Positives = 58/113 (51%), Gaps = 23/113 (20%) Query: 160 AEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEE-------------EDVSGE 206 A+G G + ++ED DEEE D+ + ED+EDEDE+E+ E ED E Sbjct: 131 AKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDE 190 Query: 207 EEEDEEGYNDGEVDDEEDEEELGEEERGQKRKR----------EPEDEGEDDD 249 ++ED+E +D E DD E+E +G+K + E EDE EDD+ Sbjct: 191 DDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDE 243 Score = 61.6 bits (148), Expect = 6e-10 Identities = 36/102 (35%), Positives = 60/102 (58%), Gaps = 18/102 (17%) Query: 155 APDSDAEGYVEGLDDEEEDEDEEEYDED-------------AQVVEDE-----EDEDEEE 196 AP S+ E + DDE++D+DEE+ E+ A+VV + EDEDEEE Sbjct: 181 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240 Query: 197 EGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRK 238 + E+ED +E+++++ D E ++EE+EEE +E G+++K Sbjct: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKK 282 Score = 58.9 bits (141), Expect = 4e-09 Identities = 40/122 (32%), Positives = 61/122 (50%), Gaps = 26/122 (21%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVV-------EDEEDEDEEEEGEEEDV 203 D E D D+E E DDE+EDEDE+E + A EDE+DED+E++ E++D Sbjct: 144 DSDEEEDDDSEEDEE--DDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDD-EDDDD 200 Query: 204 SGEEEEDEEGYND----------------GEVDDEEDEEELGEEERGQKRKREPEDEGED 247 E++ +EE V ++EDEEE E+E + + +D+ ED Sbjct: 201 DEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDED 260 Query: 248 DD 249 D+ Sbjct: 261 DE 262 Score = 58.5 bits (140), Expect = 5e-09 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 22/114 (19%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG--- 205 D D+ E A +DE++++DE++ D+D +DEED+ EEE E G Sbjct: 166 DEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDD----DDEEDDSEEEAMETTPAKGKKA 221 Query: 206 ---------------EEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDE 244 +EEED+E +D + +D+ED+++ +EE ++ + EP E Sbjct: 222 AKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275 Score = 53.1 bits (126), Expect = 2e-07 Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 19/107 (17%) Query: 146 DGYDRDDKEAPDSDAEGY----VEG----------LDDEEEDEDEEEYDEDAQVVEDEED 191 D D DD E DS+ E +G + EDEDEEE DED +D++D Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDE---DDDDD 250 Query: 192 EDEEEEGEEEDVSGEEEEDEEGYND--GEVDDEEDEEELGEEERGQK 236 ED+E++ +E+D EEEE+EE + G+ E +++ E + QK Sbjct: 251 EDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297 Score = 37.0 bits (84), Expect = 0.016 Identities = 17/65 (26%), Positives = 39/65 (60%), Gaps = 3/65 (4%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208 + DD++ D D E + DD++ED++EEE +E+ + V++ + ++E +++ ++ Sbjct: 239 EEDDEDEDDDDDE---DDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKK 295 Query: 209 EDEEG 213 + EG Sbjct: 296 QKVEG 300 Score = 31.2 bits (69), Expect = 0.88 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 2/61 (3%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEE--DEDEEEEGEEEDVSGE 206 D D+ + D D E + D+EEE+E+EEE ++A +E + E +++ V G Sbjct: 242 DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGT 301 Query: 207 E 207 E Sbjct: 302 E 302 Score = 28.5 bits (62), Expect = 5.7 Identities = 11/22 (50%), Positives = 17/22 (77%) Query: 186 VEDEEDEDEEEEGEEEDVSGEE 207 VE++ +++E E EE+D SGEE Sbjct: 24 VEEDSEDEEMSEDEEDDSSGEE 45 >gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] Length = 770 Score = 62.4 bits (150), Expect = 4e-10 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%) Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197 LL L + +R A S AE G EEE+E+EEE +E+ E+ E+E+EEEE Sbjct: 250 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 306 Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243 EEE+ EE E+ EE+ EEE + +RE E+ Sbjct: 307 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 342 Score = 52.0 bits (123), Expect = 5e-07 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221 +EE +E + D Q + D E + E G EE+ EEEE+EEG E ++ Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300 Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247 EE+EEE EEE G + E E+ Sbjct: 301 EEEEEEEEEEETGSNSEEASEQSAEE 326 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +++E + + EG + EEE+E+EEE +E+ +E E EE EE++S + Sbjct: 277 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 335 Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235 EE + E + + D + E E EEE G+ Sbjct: 336 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 368 Score = 29.6 bits (65), Expect = 2.6 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + +EA + AE E ++ EDE+ E + V E D D E E E+ GE Sbjct: 315 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 372 Query: 211 EEGYNDGE 218 +G+ Sbjct: 373 SSALTEGD 380 Score = 28.9 bits (63), Expect = 4.4 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236 E + + V++E+ E+ + + +D+S E + + E +EEE EEE ++ Sbjct: 232 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 291 Query: 237 RKREPEDEGEDDD 249 E E E+++ Sbjct: 292 GSTSEESEEEEEE 304 Score = 27.7 bits (60), Expect = 9.7 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 1/76 (1%) Query: 172 EDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEE 231 +DE +E + A+V E E E + EE+D + E E ++ + + L + Sbjct: 101 KDEKRKEKWKHARVKE-REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 159 Query: 232 ERGQKRKREPEDEGED 247 ER ++R+R+ ++ ++ Sbjct: 160 ERKRERERKMREQQKE 175 >gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] Length = 780 Score = 62.4 bits (150), Expect = 4e-10 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%) Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197 LL L + +R A S AE G EEE+E+EEE +E+ E+ E+E+EEEE Sbjct: 260 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 316 Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243 EEE+ EE E+ EE+ EEE + +RE E+ Sbjct: 317 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 352 Score = 52.0 bits (123), Expect = 5e-07 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221 +EE +E + D Q + D E + E G EE+ EEEE+EEG E ++ Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310 Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247 EE+EEE EEE G + E E+ Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEE 336 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +++E + + EG + EEE+E+EEE +E+ +E E EE EE++S + Sbjct: 287 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345 Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235 EE + E + + D + E E EEE G+ Sbjct: 346 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 378 Score = 29.6 bits (65), Expect = 2.6 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + +EA + AE E ++ EDE+ E + V E D D E E E+ GE Sbjct: 325 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 382 Query: 211 EEGYNDGE 218 +G+ Sbjct: 383 SSALTEGD 390 Score = 28.9 bits (63), Expect = 4.4 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236 E + + V++E+ E+ + + +D+S E + + E +EEE EEE ++ Sbjct: 242 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 301 Query: 237 RKREPEDEGEDDD 249 E E E+++ Sbjct: 302 GSTSEESEEEEEE 314 >gi|17975763 myelin transcription factor 1 [Homo sapiens] Length = 1121 Score = 62.4 bits (150), Expect = 4e-10 Identities = 32/73 (43%), Positives = 47/73 (64%) Query: 168 DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEE 227 +DEEE+E+EEE +ED + E+EE+E+EEEE EEE+ EEEE+EE +V +ED Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319 Query: 228 LGEEERGQKRKRE 240 ++ + R E Sbjct: 320 TSAQKAPELRGPE 332 Score = 60.5 bits (145), Expect = 1e-09 Identities = 32/61 (52%), Positives = 42/61 (68%), Gaps = 9/61 (14%) Query: 167 LDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEE 226 L EEEDE+EEE +E+ + E+EE+E+EEEE EEE+ EEEE+EE EE+EE Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE---------EEEEE 305 Query: 227 E 227 E Sbjct: 306 E 306 Score = 58.2 bits (139), Expect = 7e-09 Identities = 29/68 (42%), Positives = 44/68 (64%) Query: 165 EGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEED 224 + L+D +E ++ + EDEE+E+EEEE EE++ EEEE+EE + E ++EE+ Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297 Query: 225 EEELGEEE 232 EEE EEE Sbjct: 298 EEEEEEEE 305 Score = 57.8 bits (138), Expect = 9e-09 Identities = 31/92 (33%), Positives = 51/92 (55%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 +D + +S + + ++E+E+E+EEE +E+ E+EE+E+EEEE EEE+ EEEE+ Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300 Query: 211 EEGYNDGEVDDEEDEEELGEEERGQKRKREPE 242 EE + D E+ + R PE Sbjct: 301 EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPE 332 Score = 57.0 bits (136), Expect = 1e-08 Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 1/77 (1%) Query: 172 EDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEE 231 ED EE + ++ EE EDEEEE EEE+ +EEE+EE + E ++EE+EEE EE Sbjct: 241 EDAASEESSKQKGILSHEE-EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299 Query: 232 ERGQKRKREPEDEGEDD 248 E ++ + P+ ++D Sbjct: 300 EEEEEEEAAPDVIFQED 316 Score = 51.6 bits (122), Expect = 6e-07 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 12/94 (12%) Query: 163 YVEGLDDEEEDEDEEEYDEDA--QVVEDEEDEDEEEEG-----EEEDVSGEEEEDEEGYN 215 +++ D EE E E +D Q +ED E+ ++ EEED EEEE+EE Sbjct: 215 FIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEE--- 271 Query: 216 DGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 E D+EE+EEE EEE ++ + E E+E E+++ Sbjct: 272 --EEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303 Score = 47.8 bits (112), Expect = 9e-06 Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 13/115 (11%) Query: 148 YDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEE 207 ++ +D+E + + E + ++EEE+E+EEE +E+ + E+EE+E+EEEE + + E+ Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316 Query: 208 EEDEEGYNDGEVDDEEDEEELGE-------------EERGQKRKREPEDEGEDDD 249 E+ E E +E RK DE E D Sbjct: 317 TSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQD 371 Score = 42.0 bits (97), Expect = 5e-04 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 7/63 (11%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205 D + +++E + D E E ++EEE+E+EEE +E E+EE+E+EEEE DV Sbjct: 261 DEEEEEEEEEEEEDEEEEEE--EEEEEEEEEEEEEE-----EEEEEEEEEEEEAAPDVIF 313 Query: 206 EEE 208 +E+ Sbjct: 314 QED 316 Score = 38.5 bits (88), Expect = 0.006 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 4/87 (4%) Query: 165 EGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEE--EDVSGEEEEDEEGYNDGEVDDE 222 EG EE ++ EDA+ V + E ++ + ED + EE ++G E +DE Sbjct: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262 Query: 223 EDEEELGEEERGQKRKREPEDEGEDDD 249 E EE EEE + + E E+E E+++ Sbjct: 263 E--EEEEEEEEEEDEEEEEEEEEEEEE 287 >gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform 9 [Homo sapiens] Length = 771 Score = 62.4 bits (150), Expect = 4e-10 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%) Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197 LL L + +R A S AE G EEE+E+EEE +E+ E+ E+E+EEEE Sbjct: 251 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 307 Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243 EEE+ EE E+ EE+ EEE + +RE E+ Sbjct: 308 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 343 Score = 52.0 bits (123), Expect = 5e-07 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221 +EE +E + D Q + D E + E G EE+ EEEE+EEG E ++ Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 301 Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247 EE+EEE EEE G + E E+ Sbjct: 302 EEEEEEEEEEETGSNSEEASEQSAEE 327 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +++E + + EG + EEE+E+EEE +E+ +E E EE EE++S + Sbjct: 278 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 336 Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235 EE + E + + D + E E EEE G+ Sbjct: 337 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 369 Score = 29.6 bits (65), Expect = 2.6 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + +EA + AE E ++ EDE+ E + V E D D E E E+ GE Sbjct: 316 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 373 Query: 211 EEGYNDGE 218 +G+ Sbjct: 374 SSALTEGD 381 Score = 28.9 bits (63), Expect = 4.4 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236 E + + V++E+ E+ + + +D+S E + + E +EEE EEE ++ Sbjct: 233 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 292 Query: 237 RKREPEDEGEDDD 249 E E E+++ Sbjct: 293 GSTSEESEEEEEE 305 >gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8 [Homo sapiens] Length = 780 Score = 62.4 bits (150), Expect = 4e-10 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%) Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197 LL L + +R A S AE G EEE+E+EEE +E+ E+ E+E+EEEE Sbjct: 260 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 316 Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243 EEE+ EE E+ EE+ EEE + +RE E+ Sbjct: 317 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 352 Score = 52.0 bits (123), Expect = 5e-07 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221 +EE +E + D Q + D E + E G EE+ EEEE+EEG E ++ Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310 Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247 EE+EEE EEE G + E E+ Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEE 336 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +++E + + EG + EEE+E+EEE +E+ +E E EE EE++S + Sbjct: 287 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345 Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235 EE + E + + D + E E EEE G+ Sbjct: 346 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 378 Score = 29.6 bits (65), Expect = 2.6 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + +EA + AE E ++ EDE+ E + V E D D E E E+ GE Sbjct: 325 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 382 Query: 211 EEGYNDGE 218 +G+ Sbjct: 383 SSALTEGD 390 Score = 28.9 bits (63), Expect = 4.4 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236 E + + V++E+ E+ + + +D+S E + + E +EEE EEE ++ Sbjct: 242 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 301 Query: 237 RKREPEDEGEDDD 249 E E E+++ Sbjct: 302 GSTSEESEEEEEE 314 >gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform 5 [Homo sapiens] Length = 748 Score = 62.4 bits (150), Expect = 4e-10 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%) Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197 LL L + +R A S AE G EEE+E+EEE +E+ E+ E+E+EEEE Sbjct: 228 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 284 Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243 EEE+ EE E+ EE+ EEE + +RE E+ Sbjct: 285 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 320 Score = 52.0 bits (123), Expect = 5e-07 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221 +EE +E + D Q + D E + E G EE+ EEEE+EEG E ++ Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 278 Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247 EE+EEE EEE G + E E+ Sbjct: 279 EEEEEEEEEEETGSNSEEASEQSAEE 304 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +++E + + EG + EEE+E+EEE +E+ +E E EE EE++S + Sbjct: 255 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 313 Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235 EE + E + + D + E E EEE G+ Sbjct: 314 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 346 Score = 29.6 bits (65), Expect = 2.6 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + +EA + AE E ++ EDE+ E + V E D D E E E+ GE Sbjct: 293 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 350 Query: 211 EEGYNDGE 218 +G+ Sbjct: 351 SSALTEGD 358 Score = 28.9 bits (63), Expect = 4.4 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236 E + + V++E+ E+ + + +D+S E + + E +EEE EEE ++ Sbjct: 210 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 269 Query: 237 RKREPEDEGEDDD 249 E E E+++ Sbjct: 270 GSTSEESEEEEEE 282 >gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform 4 [Homo sapiens] Length = 737 Score = 62.4 bits (150), Expect = 4e-10 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%) Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197 LL L + +R A S AE G EEE+E+EEE +E+ E+ E+E+EEEE Sbjct: 217 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 273 Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243 EEE+ EE E+ EE+ EEE + +RE E+ Sbjct: 274 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 309 Score = 52.0 bits (123), Expect = 5e-07 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221 +EE +E + D Q + D E + E G EE+ EEEE+EEG E ++ Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 267 Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247 EE+EEE EEE G + E E+ Sbjct: 268 EEEEEEEEEEETGSNSEEASEQSAEE 293 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +++E + + EG + EEE+E+EEE +E+ +E E EE EE++S + Sbjct: 244 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 302 Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235 EE + E + + D + E E EEE G+ Sbjct: 303 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 335 Score = 29.6 bits (65), Expect = 2.6 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + +EA + AE E ++ EDE+ E + V E D D E E E+ GE Sbjct: 282 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 339 Query: 211 EEGYNDGE 218 +G+ Sbjct: 340 SSALTEGD 347 Score = 28.9 bits (63), Expect = 4.4 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236 E + + V++E+ E+ + + +D+S E + + E +EEE EEE ++ Sbjct: 199 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 258 Query: 237 RKREPEDEGEDDD 249 E E E+++ Sbjct: 259 GSTSEESEEEEEE 271 >gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform 3 [Homo sapiens] Length = 526 Score = 62.4 bits (150), Expect = 4e-10 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%) Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197 LL L + +R A S AE G EEE+E+EEE +E+ E+ E+E+EEEE Sbjct: 6 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 62 Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243 EEE+ EE E+ EE+ EEE + +RE E+ Sbjct: 63 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 98 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +++E + + EG + EEE+E+EEE +E+ +E E EE EE++S + Sbjct: 33 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 91 Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235 EE + E + + D + E E EEE G+ Sbjct: 92 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 124 Score = 50.4 bits (119), Expect = 1e-06 Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 5/81 (6%) Query: 167 LDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEE 226 L D ++ D E A+ E EEE EEE EEE+EEG E ++EE+EE Sbjct: 7 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE-----EEEEEEGSTSEESEEEEEEE 61 Query: 227 ELGEEERGQKRKREPEDEGED 247 E EEE G + E E+ Sbjct: 62 EEEEEETGSNSEEASEQSAEE 82 Score = 29.6 bits (65), Expect = 2.6 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + +EA + AE E ++ EDE+ E + V E D D E E E+ GE Sbjct: 71 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 128 Query: 211 EEGYNDGE 218 +G+ Sbjct: 129 SSALTEGD 136 >gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform 2 [Homo sapiens] Length = 782 Score = 62.4 bits (150), Expect = 4e-10 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%) Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197 LL L + +R A S AE G EEE+E+EEE +E+ E+ E+E+EEEE Sbjct: 262 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 318 Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243 EEE+ EE E+ EE+ EEE + +RE E+ Sbjct: 319 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 354 Score = 52.0 bits (123), Expect = 5e-07 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%) Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221 +EE +E + D Q + D E + E G EE+ EEEE+EEG E ++ Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 312 Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247 EE+EEE EEE G + E E+ Sbjct: 313 EEEEEEEEEEETGSNSEEASEQSAEE 338 Score = 51.6 bits (122), Expect = 6e-07 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%) Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206 G + +++E + + EG + EEE+E+EEE +E+ +E E EE EE++S + Sbjct: 289 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 347 Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235 EE + E + + D + E E EEE G+ Sbjct: 348 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 380 Score = 31.6 bits (70), Expect = 0.67 Identities = 19/83 (22%), Positives = 39/83 (46%), Gaps = 2/83 (2%) Query: 167 LDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEE 226 + DE++ + DE Q + ++++E+ E + S + + + +GE+ D E Sbjct: 1 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60 Query: 227 ELGEEERGQKRKREPEDEGEDDD 249 + +R+ ED GE+DD Sbjct: 61 TIRNSP--YRREDSMEDRGEEDD 81 Score = 29.6 bits (65), Expect = 2.6 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%) Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210 + +EA + AE E ++ EDE+ E + V E D D E E E+ GE Sbjct: 327 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 384 Query: 211 EEGYNDGE 218 +G+ Sbjct: 385 SSALTEGD 392 Score = 28.9 bits (63), Expect = 4.4 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236 E + + V++E+ E+ + + +D+S E + + E +EEE EEE ++ Sbjct: 244 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 303 Query: 237 RKREPEDEGEDDD 249 E E E+++ Sbjct: 304 GSTSEESEEEEEE 316 >gi|11545835 TSPY-like 2 [Homo sapiens] Length = 693 Score = 62.4 bits (150), Expect = 4e-10 Identities = 49/205 (23%), Positives = 85/205 (41%), Gaps = 29/205 (14%) Query: 65 KLKKLELSDNRVSGGLEV-LAEKCPNLTHLNLSGNKIKDLS-TIEPLKKLENLKSLDLFN 122 K KK E+ + G EV + E P+ + ++I D+ TI +K + +++ D F Sbjct: 404 KRKKQEMKKRKTRGRCEVVIMEDAPDYYAVEDIFSEISDIDETIHDIKISDFMETTDYFE 463 Query: 123 CEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDED 182 + D EN+ D + D E P+++ E DD E ++ E D++ Sbjct: 464 TTDNEITDINENI---------CDSENPDHNEVPNNETTDNNESADDHETTDNNESADDN 514 Query: 183 AQVVEDEE---DEDEEEEGEEEDVSG---------------EEEEDEEGYNDGEVDDEED 224 + ED D++EE E+ G ++ D + D DDE++ Sbjct: 515 NENPEDNNKNTDDNEENPNNNENTYGNNFFKGGFWGSHGNNQDSSDSDNEADEASDDEDN 574 Query: 225 EEELGEEERGQKRKREPEDEGEDDD 249 + G+ E E ++EG DDD Sbjct: 575 DGNEGDNEGSDDDGNEGDNEGSDDD 599 Score = 52.4 bits (124), Expect = 4e-07 Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 9/104 (8%) Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205 DG + D++ + D EG EG DD+ D D E Y+ +V+ED D+D+ + + ++ Sbjct: 575 DGNEGDNEGSDDDGNEGDNEGSDDD--DRDIEYYE---KVIED-FDKDQADYEDVIEIIS 628 Query: 206 EEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249 +E +EEG +G DE+ EE EE G + + +EGED D Sbjct: 629 DESVEEEGIEEGIQQDEDIYEEGNYEEEGSE---DVWEEGEDSD 669 Score = 45.1 bits (105), Expect = 6e-05 Identities = 28/93 (30%), Positives = 53/93 (56%), Gaps = 9/93 (9%) Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEE-EEG--EEEDV-- 203 D + + D D E Y + ++D D+D+ +Y++ +++ DE E+E EEG ++ED+ Sbjct: 592 DNEGSDDDDRDIEYYEKVIED--FDKDQADYEDVIEIISDESVEEEGIEEGIQQDEDIYE 649 Query: 204 --SGEEEEDEEGYNDGEVDDEEDEEELGEEERG 234 + EEE E+ + +GE D+ D E++ + G Sbjct: 650 EGNYEEEGSEDVWEEGEDSDDSDLEDVLQVPNG 682 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.302 0.131 0.349 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,006,661 Number of Sequences: 37866 Number of extensions: 690951 Number of successful extensions: 52009 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1313 Number of HSP's successfully gapped in prelim test: 657 Number of HSP's that attempted gapping in prelim test: 6454 Number of HSP's gapped (non-prelim): 17864 length of query: 249 length of database: 18,247,518 effective HSP length: 100 effective length of query: 149 effective length of database: 14,460,918 effective search space: 2154676782 effective search space used: 2154676782 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.7 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.