Guide to the Human Genome
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Search of human proteins with 5453880

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32
family, member A [Homo sapiens]
         (249 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   500   e-142
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]           388   e-108
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...   347   7e-96
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...   298   4e-81
gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear...   270   7e-73
gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear...   270   7e-73
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   241   6e-64
gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]          232   3e-61
gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]          206   2e-53
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...   191   5e-49
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    76   2e-14
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          70   1e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    70   2e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    70   2e-12
gi|21735415 centromere protein B [Homo sapiens]                        66   2e-11
gi|31621309 leucine rich repeat containing 6 [Homo sapiens]            65   6e-11
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           65   7e-11
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  65   7e-11
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           65   7e-11
gi|55956788 nucleolin [Homo sapiens]                                   64   2e-10
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     62   4e-10
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     62   4e-10
gi|17975763 myelin transcription factor 1 [Homo sapiens]               62   4e-10
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    62   4e-10
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    62   4e-10
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    62   4e-10
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...    62   4e-10
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...    62   4e-10
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...    62   4e-10
gi|11545835 TSPY-like 2 [Homo sapiens]                                 62   4e-10

>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score =  500 bits (1288), Expect = e-142
 Identities = 249/249 (100%), Positives = 249/249 (100%)

Query: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60
           MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL
Sbjct: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60

Query: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120
           PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL
Sbjct: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120

Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD 180
           FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD
Sbjct: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD 180

Query: 181 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKRE 240
           EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKRE
Sbjct: 181 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKRE 240

Query: 241 PEDEGEDDD 249
           PEDEGEDDD
Sbjct: 241 PEDEGEDDD 249


>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
          Length = 234

 Score =  388 bits (997), Expect = e-108
 Identities = 205/238 (86%), Positives = 212/238 (89%), Gaps = 4/238 (1%)

Query: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60
           MEMGRRIH ELRNR PSDVKEL LDNSRSNEGKLE LTDEFEELEFLS IN GLTSI++L
Sbjct: 1   MEMGRRIHSELRNRAPSDVKELALDNSRSNEGKLEALTDEFEELEFLSKINGGLTSISDL 60

Query: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120
           PKL KL+KLEL   RVSGGLEVLAEKCPNLTHL LSGNKIKDLSTIEPLK+LENLKSLDL
Sbjct: 61  PKL-KLRKLEL---RVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDL 116

Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD 180
           FNCEVTNLNDY ENVFKLL QLTYLD    D KEAP SD E +VEGLDDEEE E EEEYD
Sbjct: 117 FNCEVTNLNDYGENVFKLLLQLTYLDSCYWDHKEAPYSDIEDHVEGLDDEEEGEHEEEYD 176

Query: 181 EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRK 238
           EDAQVVEDEE E+EEEEGEEEDVSG +EEDEEGYNDGEVD EEDEEELGEEERGQKRK
Sbjct: 177 EDAQVVEDEEGEEEEEEGEEEDVSGGDEEDEEGYNDGEVDGEEDEEELGEEERGQKRK 234


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score =  347 bits (889), Expect = 7e-96
 Identities = 178/254 (70%), Positives = 216/254 (85%), Gaps = 9/254 (3%)

Query: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60
           M+M RRIHLELRNRTP+ V+ELVLDN +SN+GK+EGLT EF  LEFLS INVGL S++NL
Sbjct: 1   MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNL 60

Query: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120
           PKL KLKKLELS+NR+ GGL++LAEK PNLTHLNLSGNK+KD+ST+EPLKKLE LKSLDL
Sbjct: 61  PKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDL 120

Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDE----DE 176
           FNCEVTNLNDYRE+VFKLLPQLTYLDGYDR+D+EAPDSDAE  V+G+D+EEEDE    +E
Sbjct: 121 FNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAE--VDGVDEEEEDEEGEDEE 178

Query: 177 EEYDEDAQVVE--DEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERG 234
           +E DED +  E  +E+DEDE+ EG+E+D    EEE+E G ++ + D++EDEEE  E  +G
Sbjct: 179 DEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEE-EEGGKG 237

Query: 235 QKRKREPEDEGEDD 248
           +KRKRE +DEGEDD
Sbjct: 238 EKRKRETDDEGEDD 251


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score =  298 bits (762), Expect = 4e-81
 Identities = 158/267 (59%), Positives = 204/267 (76%), Gaps = 18/267 (6%)

Query: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60
           MEM ++I+LELRNR+P +V ELVLDN     G++EGL D F+ELEFLS  NV L+S+A L
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARL 60

Query: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120
           P LNKL+KLELSDN +SGGLEVLAEKCPNLT+LNLSGNKIKDLST+E L+ L+NLKSLDL
Sbjct: 61  PSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDL 120

Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY 179
           FNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E   +G  DDEEE+E+E   
Sbjct: 121 FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 180

Query: 180 DEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEEDEE---ELGE 230
            E  +  E+EE+E++E+E E+ED +G    E E+E G +     E+ DEED++   E GE
Sbjct: 181 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 240

Query: 231 EE--------RGQKRKREPEDEGEDDD 249
           EE        RG+KRKR+ ED+GE++D
Sbjct: 241 EEEEEEEGGLRGEKRKRDAEDDGEEED 267


>gi|239756368 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  270 bits (691), Expect = 7e-73
 Identities = 143/233 (61%), Positives = 178/233 (76%), Gaps = 9/233 (3%)

Query: 19  VKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSG 78
           V+E VLDN +SN+ K+E LT EF  LEFL  INVGL SI+NLPKL KLKK  LS+NR+ G
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 79  GLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKL 138
           GL + AEK PNLTHLNLSG K+KD+ST+EPLKKLE LKSLDLFNCEV NLNDY+E+VFKL
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158

Query: 139 LPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDE------DEEEYDEDAQVVEDEEDE 192
           LPQLT LD YD +D+EAPDSDA+  V+G+D EEEDE      D E  D + + +++EEDE
Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ--VDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDE 216

Query: 193 DEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEE-RGQKRKREPEDE 244
           DE+ EG+++     EEE+E G +  E D++EDE+E  EE  +G+ RKRE +DE
Sbjct: 217 DEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDE 269


>gi|239750893 PREDICTED: similar to acidic (leucine-rich) nuclear
           phosphoprotein 32 family, member B [Homo sapiens]
          Length = 272

 Score =  270 bits (691), Expect = 7e-73
 Identities = 143/233 (61%), Positives = 178/233 (76%), Gaps = 9/233 (3%)

Query: 19  VKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSG 78
           V+E VLDN +SN+ K+E LT EF  LEFL  INVGL SI+NLPKL KLKK  LS+NR+ G
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 79  GLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKL 138
           GL + AEK PNLTHLNLSG K+KD+ST+EPLKKLE LKSLDLFNCEV NLNDY+E+VFKL
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158

Query: 139 LPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDE------DEEEYDEDAQVVEDEEDE 192
           LPQLT LD YD +D+EAPDSDA+  V+G+D EEEDE      D E  D + + +++EEDE
Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ--VDGVDKEEEDEEGEDEKDXENEDGEEEELDEEEDE 216

Query: 193 DEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEE-RGQKRKREPEDE 244
           DE+ EG+++     EEE+E G +  E D++EDE+E  EE  +G+ RKRE +DE
Sbjct: 217 DEDVEGDDDKDEVSEEEEEFGLDKDEDDEDEDEDEEEEESGKGENRKRETDDE 269


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score =  241 bits (614), Expect = 6e-64
 Identities = 128/217 (58%), Positives = 166/217 (76%), Gaps = 18/217 (8%)

Query: 51  NVGLTSIANLPKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLK 110
           NV L+S+A LP LNKL+KLELSDN +SGGLEVLAEKCPNLT+LNLSGNKIKDLST+E L+
Sbjct: 3   NVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQ 62

Query: 111 KLENLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDD 169
            L+NLKSLDLFNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E   +G  DD
Sbjct: 63  NLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDD 122

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEE 223
           EEE+E+E    E  +  E+EE+E++E+E E+ED +G    E E+E G +     E+ DEE
Sbjct: 123 EEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEE 182

Query: 224 DEE---ELGEEE--------RGQKRKREPEDEGEDDD 249
           D++   E GEEE        RG+KRKR+ ED+GE++D
Sbjct: 183 DDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEED 219


>gi|21071028 acidic nuclear phosphoprotein 32D [Homo sapiens]
          Length = 131

 Score =  232 bits (591), Expect = 3e-61
 Identities = 117/131 (89%), Positives = 123/131 (93%)

Query: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60
           MEMG+ IHLELRNRTPSDVKEL LDNS+SNEGKLEGLTDEFEELE L+TIN+GLTSIANL
Sbjct: 1   MEMGKWIHLELRNRTPSDVKELFLDNSQSNEGKLEGLTDEFEELELLNTINIGLTSIANL 60

Query: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120
           PKLNKLKKLELS NR S GLEVLAEKCPNL HLNLSGNKIKDLSTIEPLKKLENL+SLDL
Sbjct: 61  PKLNKLKKLELSSNRASVGLEVLAEKCPNLIHLNLSGNKIKDLSTIEPLKKLENLESLDL 120

Query: 121 FNCEVTNLNDY 131
           F CEVTNLN+Y
Sbjct: 121 FTCEVTNLNNY 131


>gi|239745256 PREDICTED: similar to hCG1791241 [Homo sapiens]
          Length = 450

 Score =  206 bits (524), Expect = 2e-53
 Identities = 104/143 (72%), Positives = 120/143 (83%)

Query: 19  VKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSG 78
           V+E VLDN +SN+ K+E LT EF  LEFL  INVGL SI+NLPKL KLKK  LS+NR+ G
Sbjct: 39  VREHVLDNCKSNDWKIESLTAEFVNLEFLRLINVGLISISNLPKLPKLKKFVLSENRIFG 98

Query: 79  GLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKL 138
           GL + AEK PNLTHLNLSG K+KD+ST+EPLKKLE LKSLDLFNCEV NLNDY+E+VFKL
Sbjct: 99  GLNMSAEKLPNLTHLNLSGKKLKDISTLEPLKKLECLKSLDLFNCEVINLNDYQESVFKL 158

Query: 139 LPQLTYLDGYDRDDKEAPDSDAE 161
           LPQLT LD YD +D+EAPDSDA+
Sbjct: 159 LPQLTCLDTYDPEDQEAPDSDAQ 181


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score =  191 bits (485), Expect = 5e-49
 Identities = 119/267 (44%), Positives = 165/267 (61%), Gaps = 59/267 (22%)

Query: 1   MEMGRRIHLELRNRTPSDVKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANL 60
           MEM ++I+LELRNR+P +V ELVLDN     G++EGL D F+ELEFLS  NV        
Sbjct: 1   MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANV-------- 52

Query: 61  PKLNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDL 120
            +L+ L +L                  P+L       NK++        + L+NLKSLDL
Sbjct: 53  -ELSSLARL------------------PSL-------NKLRK-------QNLKNLKSLDL 79

Query: 121 FNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEG-LDDEEEDEDEEEY 179
           FNCE+TNL DYRE++F+LL Q+TYLDG+D++D EAPDS+ E   +G  DDEEE+E+E   
Sbjct: 80  FNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGP 139

Query: 180 DEDAQVVEDEEDEDEEEEGEEEDVSGE---EEEDEEGYN---DGEVDDEEDEE---ELGE 230
            E  +  E+EE+E++E+E E+ED +G    E E+E G +     E+ DEED++   E GE
Sbjct: 140 PEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE 199

Query: 231 EE--------RGQKRKREPEDEGEDDD 249
           EE        RG+KRKR+ ED+GE++D
Sbjct: 200 EEEEEEEGGLRGEKRKRDAEDDGEEED 226


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 47/98 (47%), Positives = 61/98 (62%), Gaps = 3/98 (3%)

Query: 154  EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE-EEEGE-EEDVSGEEEEDE 211
            E  + + EG  EG  + EE E E E +E     E+EE E+E EEEGE EE+  GE EE+E
Sbjct: 958  EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017

Query: 212  EGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
            EG  +GEV+ EE E E GEEE G++   E E EGE ++
Sbjct: 1018 EGEVEGEVEGEEGEGE-GEEEEGEEEGEEREKEGEGEE 1054



 Score = 68.6 bits (166), Expect = 5e-12
 Identities = 45/109 (41%), Positives = 60/109 (55%), Gaps = 10/109 (9%)

Query: 150 RDDKEAPDSDAEGYVE-GLDDEEEDEDEEEYDEDAQVVEDEEDEDEEE------EGEEED 202
           + ++E  + + EG  E G  +EEE E EEE  E     E EE E EEE      EGEEE+
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882

Query: 203 VSGEEEEDEEG---YNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248
             GE EE+ EG     +GE + EE+ E  GEEE G+ +  E  +EGE +
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE 931



 Score = 68.6 bits (166), Expect = 5e-12
 Identities = 42/106 (39%), Positives = 59/106 (55%), Gaps = 7/106 (6%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE---E 207
           ++ E  +   EG  EG ++E E E EEE + + +  E E + +EE EGE E+  GE   E
Sbjct: 863 EEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE 922

Query: 208 EEDEEGYNDGEVD----DEEDEEELGEEERGQKRKREPEDEGEDDD 249
           EE EEG  +GE +    + ED E  GEEE G+    E E EGE ++
Sbjct: 923 EEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968



 Score = 68.6 bits (166), Expect = 5e-12
 Identities = 42/105 (40%), Positives = 59/105 (56%), Gaps = 5/105 (4%)

Query: 146  DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGE--EEDV 203
            +G   ++ E    + EG  +G ++ EE E E E +E     ED E E EEEEGE   E+ 
Sbjct: 901  EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960

Query: 204  SGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248
             GE E +EEG  +GE  + E EEE GE   G+  + E E+EGE++
Sbjct: 961  EGEGEGEEEGEGEGEEGEGEGEEEEGE---GEGEEEEGEEEGEEE 1002



 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 40/105 (38%), Positives = 59/105 (56%), Gaps = 1/105 (0%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEE-DVS 204
           +G   + +E  + +     EG  + EE+E+E E +E+    E+EE E EEEEGE + +  
Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEE 861

Query: 205 GEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           GEE E EE   +GE + EE+E E   EE G+    E E EGE ++
Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEE 906



 Score = 68.2 bits (165), Expect = 7e-12
 Identities = 42/106 (39%), Positives = 61/106 (57%), Gaps = 2/106 (1%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205
           +G    ++E  + + E   EG  +EEE E E E + + +  E+E +   EEEGEE +  G
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932

Query: 206 EEEEDEEGYNDGEVDDEEDEEEL-GEEERGQ-KRKREPEDEGEDDD 249
           EEEE E    DGE + EE+E E  GEEE G+ + + E E EGE+ +
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE 978



 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 41/93 (44%), Positives = 55/93 (59%), Gaps = 5/93 (5%)

Query: 161 EGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE----EDEEGYND 216
           E   EG  +E+E+  E E  E  +   + E+E+EE EGEEE+  GEEE    E+EEG   
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857

Query: 217 GEVDDEEDE-EELGEEERGQKRKREPEDEGEDD 248
           GE + EE E EE GEE  G+  + E E EGE++
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEE 890



 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 46/117 (39%), Positives = 64/117 (54%), Gaps = 16/117 (13%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEED-----EDEEEYDEDAQVVEDEEDEDEEEEGE---E 200
           + ++ E  + + EG  E  + EEE+     E+E E  E  +  E+ E E EEEEGE   E
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGE 888

Query: 201 EDVSGEEEEDE---EGYNDGEVDDEEDE-----EELGEEERGQKRKREPEDEGEDDD 249
           E+  GE EE+E   EG  +GE + EE+E     EE GEE  G+  + E E EGED +
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGE 945



 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 41/106 (38%), Positives = 61/106 (57%), Gaps = 7/106 (6%)

Query: 151  DDKEAPDSDAEGYVEGLDDEEEDEDEE-EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEE 209
            ++ E    + EG  EG D E E E+EE E++ + +  E E +E+ E EGEE +  GEEEE
Sbjct: 926  EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985

Query: 210  ------DEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
                  +EEG  +GE + E +EE  GE E  ++ + E E EGE+ +
Sbjct: 986  GEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031



 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 42/112 (37%), Positives = 61/112 (54%), Gaps = 13/112 (11%)

Query: 151 DDKEAPDSDAEGYVEGLDDE-----EEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205
           D +E  + + EG  EG  +E     E++E E + +E A   E  E+E ++ EGEEE+  G
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803

Query: 206 EEEEDEEG--YNDGEVD------DEEDEEELGEEERGQKRKREPEDEGEDDD 249
             EE EEG     GEV+      +EE+EE  GEEE G+  + E E E E+ +
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE 855



 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 40/106 (37%), Positives = 61/106 (57%), Gaps = 5/106 (4%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEE--EGEEEDV 203
           +G   +++   + + EG  EG ++E E + EEE +E     E+EE E E E  EGE E+ 
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951

Query: 204 SGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
            GE E +EE   +GE + EE+ E  GEE  G+  + E E EGE+++
Sbjct: 952 EGEWEGEEE---EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEE 994



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 42/111 (37%), Positives = 62/111 (55%), Gaps = 7/111 (6%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDE---EDEDEEEEGEEED 202
           +G   +++   + + EG  EG ++E E E EEE + + +  E E   E+E EE EGE E+
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934

Query: 203 VSGEEE-EDEEGYND---GEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
             GE E ED EG  +   GE + EE+E E   EE G+    E E EGE+++
Sbjct: 935 EEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEE 985



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 43/101 (42%), Positives = 58/101 (57%), Gaps = 7/101 (6%)

Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE-EEEDEE 212
           E  + + EG  EG ++E E E+EE   E+ +     E+E EE EGEEE   GE E E+EE
Sbjct: 825 EREEEEEEG--EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882

Query: 213 GYNDGEVDDE-EDEEELGE---EERGQKRKREPEDEGEDDD 249
           G  +GE + E E EEE GE   EE G+    E E EG+ ++
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923



 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 42/97 (43%), Positives = 53/97 (54%), Gaps = 4/97 (4%)

Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDE-EDEDEEEEGEEEDVSGEEEEDEE 212
           E    + EG  EG  +E E E EEE  E     E E E E+EE EGE E+    E E+EE
Sbjct: 859 EEEGEEGEGEEEG--EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916

Query: 213 GYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           G   GE + EE E E GEEE G+    + E EGE+++
Sbjct: 917 GEGKGEEEGEEGEGE-GEEEEGEGEGEDGEGEGEEEE 952



 Score = 62.8 bits (151), Expect = 3e-10
 Identities = 44/105 (41%), Positives = 61/105 (58%), Gaps = 4/105 (3%)

Query: 146  DGYDRDDKEAPDSDAEGYVEGLDDEEED-EDEEEYDEDAQVVEDEEDEDE-EEEGEEEDV 203
            +G  + ++E  + + EG  E  + E ED E E E +E     E+EE E E EEEGE E  
Sbjct: 916  EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE 975

Query: 204  SGE-EEEDEEGYNDGEVDD-EEDEEELGEEERGQKRKREPEDEGE 246
             GE E E+EEG  +GE ++ EE+ EE GE E   + + E E+EGE
Sbjct: 976  EGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 41/108 (37%), Positives = 62/108 (57%), Gaps = 16/108 (14%)

Query: 157 DSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGE--EEDVSGEEEEDEEGY 214
           +   EG  E  D EEE+E E E  E+ +  E+ E E E+EEGE  +E+ +G+EE+ EE  
Sbjct: 733 EEHGEGEEEEGDREEEEEKEGEGKEEGEG-EEVEGEREKEEGERKKEERAGKEEKGEEEG 791

Query: 215 NDGEVDDEEDE------EELG-------EEERGQKRKREPEDEGEDDD 249
           + GE ++EE E      EE G       EE +G++ + E E EGE+++
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839



 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 38/102 (37%), Positives = 57/102 (55%), Gaps = 7/102 (6%)

Query: 146  DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDE-EDEDEEEEGEEEDVS 204
            +G + + +E  + + EG  EG   E E E+EEE + + +V  +E E E EEEEGEEE   
Sbjct: 989  EGEEEEGEEEGEEEGEGEEEG---EGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEE--- 1042

Query: 205  GEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGE 246
            GEE E E    +   + EE+EEE G+ +   + + E +D  E
Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084



 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 34/105 (32%), Positives = 57/105 (54%), Gaps = 4/105 (3%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE-EEEGEEEDVS 204
           DG +++ KE      +   + +++  E+E  E  +E+    E+EE E E +EEGE E+V 
Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE 765

Query: 205 GEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           GE E++E    + + ++   +EE GEEE  Q    E E EG  ++
Sbjct: 766 GEREKEE---GERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807



 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 38/96 (39%), Positives = 52/96 (54%), Gaps = 5/96 (5%)

Query: 154  EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEG 213
            E  + + EG  EG + EEE E E E +E+ +V  + E E+ E EGEEE+    EEE EE 
Sbjct: 991  EEEEGEEEGEEEG-EGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE---GEEEGEER 1046

Query: 214  YNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
              +GE ++     E  EEE G K +   E+E E  D
Sbjct: 1047 EKEGEGEENRRNREEEEEEEG-KYQETGEEENERQD 1081



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 34/108 (31%), Positives = 56/108 (51%), Gaps = 9/108 (8%)

Query: 150 RDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEE 209
           R + E P    +   E  + ++ D +E+E  E  Q  + E +++ EE GEEE   GEEEE
Sbjct: 683 RGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE 742

Query: 210 DE---------EGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248
            +         EG  +GE ++ E E E  E ER ++ +   E++GE++
Sbjct: 743 GDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 41/116 (35%), Positives = 60/116 (51%), Gaps = 20/116 (17%)

Query: 152 DKEAPDSDAEGYVEGLDDEEEDEDEEEYDE-------DAQVVEDEEDEDE---------- 194
           ++E  +   E + EG ++EE D +EEE  E       + + VE E +++E          
Sbjct: 724 NQEMEEGGEEEHGEG-EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAG 782

Query: 195 -EEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
            EE+GEEE   GE EE EE    GE  +E  E E GE E G+  + E E+EGE ++
Sbjct: 783 KEEKGEEEGDQGEGEE-EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEE 837



 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 34/94 (36%), Positives = 50/94 (53%), Gaps = 1/94 (1%)

Query: 153 KEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEE 212
           KE      EG  E   + EE+E + E +E+ +    EE E EE EGE E   GE +++E 
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780

Query: 213 GYNDGEVDDEEDEEELGEEERGQKRKREPEDEGE 246
              + + ++E D+ E GEEE  + R  E E+ GE
Sbjct: 781 AGKEEKGEEEGDQGE-GEEEETEGRGEEKEEGGE 813



 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 8/95 (8%)

Query: 151  DDKEAPDSDAEGYVEGLDDE---EEDEDEEEYDEDAQVVEDEE-----DEDEEEEGEEED 202
            + +E  + + EG VEG + E   EE+E EEE +E  +  E EE     +E+EEEEG+ ++
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071

Query: 203  VSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKR 237
               EE E ++G    +V   +   + G+ +  QK+
Sbjct: 1072 TGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKK 1106



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 25/88 (28%), Positives = 49/88 (55%), Gaps = 3/88 (3%)

Query: 165 EGLDDEEEDEDEEEYDEDAQVVEDEE---DEDEEEEGEEEDVSGEEEEDEEGYNDGEVDD 221
           +G  D+   E E   + + ++ E EE    + EE+E +E +   ++E ++E    GE + 
Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEH 735

Query: 222 EEDEEELGEEERGQKRKREPEDEGEDDD 249
            E EEE G+ E  ++++ E ++EGE ++
Sbjct: 736 GEGEEEEGDREEEEEKEGEGKEEGEGEE 763



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 31/102 (30%), Positives = 55/102 (53%), Gaps = 3/102 (2%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208
           ++ +K+    + E   EG  +  E E+ ++ D + Q  ++ E   ++E  +E +  GEE 
Sbjct: 675 EKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEE- 733

Query: 209 EDEEGYNDGEVDDEEDEEELGE-EERGQKRKREPEDEGEDDD 249
           E  EG  + E D EE+EE+ GE +E G+  + E E E E+ +
Sbjct: 734 EHGEG-EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGE 774



 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 28/95 (29%), Positives = 52/95 (54%), Gaps = 4/95 (4%)

Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEG 213
           E   S AE + +  ++ E+ E ++   E  +  E E++  E+EE ++ D  GEE+E +E 
Sbjct: 660 EEGSSGAEHWQD--EEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRD--GEEQEQKER 715

Query: 214 YNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248
               + +  ++ EE GEEE G+  + E + E E++
Sbjct: 716 EQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEE 750



 Score = 33.5 bits (75), Expect = 0.18
 Identities = 31/122 (25%), Positives = 50/122 (40%), Gaps = 39/122 (31%)

Query: 164 VEGLDDEEEDEDEEE---YDEDAQVVEDEEDEDEEE------------------------ 196
           +E   DEE +  EE+    D     +E++E E  EE                        
Sbjct: 576 IEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAE 635

Query: 197 --EGEEEDVSGEEEEDEEGYNDGEVDD--------EEDEEELGEEERGQKRKREPEDEGE 246
             EG+ + V GE E+  EG  DG  ++        +++E E GE+++G+     P  EGE
Sbjct: 636 VSEGKAKSV-GEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERP-GEGE 693

Query: 247 DD 248
            +
Sbjct: 694 KE 695


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 46/95 (48%), Positives = 59/95 (62%), Gaps = 14/95 (14%)

Query: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEG 213
           E  DSD     E +D++EEDE  EEY ED     DE++EDEE + EEE+   EE+ED++ 
Sbjct: 89  ECDDSDG---TEDMDEKEEDEG-EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDD- 143

Query: 214 YNDGE-VDDEEDEEELGEEERGQKRKREPEDEGED 247
             DGE V+DEE+EEE  EEE       E E+E ED
Sbjct: 144 -EDGEDVEDEEEEEEEEEEE-------EEEEENED 170



 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 38/101 (37%), Positives = 60/101 (59%), Gaps = 9/101 (8%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208
           D D+KE  + + E Y E  +DE  DEDEE+ + D +  E+ E+EDE+++ + EDV  EEE
Sbjct: 98  DMDEKE--EDEGEEYSED-NDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEE 154

Query: 209 EDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           E+E      E ++EE+EEE  + +      R  +D  +DD+
Sbjct: 155 EEE------EEEEEEEEEENEDHQMNCHNTRIMQDTEKDDN 189



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 34/88 (38%), Positives = 54/88 (61%), Gaps = 6/88 (6%)

Query: 164 VEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEG--EEEDVSGEEEEDEEGYNDGEVDD 221
           V+  DD +  ED +E +ED     +E  ED +E G  +EED  G+ EE+EE   + E DD
Sbjct: 87  VDECDDSDGTEDMDEKEEDEG---EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE-DD 142

Query: 222 EEDEEELGEEERGQKRKREPEDEGEDDD 249
           +ED E++ +EE  ++ + E E+E E++D
Sbjct: 143 DEDGEDVEDEEEEEEEEEEEEEEEENED 170



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 37/86 (43%), Positives = 47/86 (54%), Gaps = 9/86 (10%)

Query: 148 YDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEE 207
           Y  D+ E  D D E   E  D EEE+E EEE ++D +  ED EDE+EEEE EEE+   EE
Sbjct: 110 YSEDNDEPGDEDEED--EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167

Query: 208 EEDEEG-------YNDGEVDDEEDEE 226
            ED +          D E DD  ++E
Sbjct: 168 NEDHQMNCHNTRIMQDTEKDDNNNDE 193



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 19/66 (28%), Positives = 39/66 (59%)

Query: 182 DAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREP 241
           D+  V++ +D D  E+ +E++    EE  E+    G+ D+E++E +  EEE  ++   + 
Sbjct: 83  DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDD 142

Query: 242 EDEGED 247
           +++GED
Sbjct: 143 DEDGED 148



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 21/80 (26%), Positives = 43/80 (53%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208
           D +D+E    + E   E  +D++ED ++ E +E+ +  E+EE+E+EE E  + +      
Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180

Query: 209 EDEEGYNDGEVDDEEDEEEL 228
             +   +D   D+ ++ +EL
Sbjct: 181 MQDTEKDDNNNDEYDNYDEL 200



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 20/79 (25%), Positives = 46/79 (58%), Gaps = 5/79 (6%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205
           +G   +++E  + D +   +G D E+E+E+EEE +E     E+EE+E+E+ +    +   
Sbjct: 126 EGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE-----EEEEEENEDHQMNCHNTRI 180

Query: 206 EEEEDEEGYNDGEVDDEED 224
            ++ +++  N+ E D+ ++
Sbjct: 181 MQDTEKDDNNNDEYDNYDE 199



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 20/104 (19%), Positives = 47/104 (45%), Gaps = 7/104 (6%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205
           DG D +D+E  + + E       +EEE+E+ E++  +       +D ++++   +E  + 
Sbjct: 145 DGEDVEDEEEEEEEEE-------EEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNY 197

Query: 206 EEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           +E   +   N G++ ++       E E         ED+ + ++
Sbjct: 198 DELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNE 241


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 39/99 (39%), Positives = 56/99 (56%), Gaps = 6/99 (6%)

Query: 156 PDSDAEGYVEGLDD------EEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEE 209
           P+ + +    GLDD      +EE E  E      +V E+ E+E+EEEE EEED   EEEE
Sbjct: 492 PEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEE 551

Query: 210 DEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDD 248
           +EEG ++G   DEEDE+   E++ G+   ++P  E   D
Sbjct: 552 EEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSD 590



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 42/113 (37%), Positives = 58/113 (51%), Gaps = 23/113 (20%)

Query: 151 DDKEAPDSDAEGY-VEGL----------DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGE 199
           DD EA  SD E   VEG           ++EEE+E+EEE DE+++  E+EE E E  EG+
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD 563

Query: 200 EEDVSGEEEED----------EEGYNDGEVDDEEDEEELGEEERGQKRKREPE 242
           EED    +E+D          +E  +D E D ++D  +  EE    K KR  E
Sbjct: 564 EEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK--EERAYDKAKRRIE 614



 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 10/90 (11%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEE---DVSGEEEEDEEGYN-------DGEV 219
           E  ++   E +E    VE EE+ED E+ G ++     S EE E  EG         + E 
Sbjct: 474 EVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEE 533

Query: 220 DDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           ++EE+EEE  +EE  ++ + E E EG + D
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGD 563



 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 1/78 (1%)

Query: 169 DEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEEL 228
           + EE+ED E+   D       ++E E+ EG +  +  +E  +EE   + E +++E+ EE 
Sbjct: 491 EPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEE- 549

Query: 229 GEEERGQKRKREPEDEGE 246
            EEE G+    E ++E E
Sbjct: 550 EEEEEGESEGSEGDEEDE 567



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 10/111 (9%)

Query: 149 DRDDKEAPDSD------AEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEED 202
           D D +E  D D      A+  VE     ++D+D  +  + A+    + ++  +   E+ED
Sbjct: 110 DNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDED 169

Query: 203 VSGEEEEDEEGYNDGEVDDEEDE--EELGEEERGQKRKREP--EDEGEDDD 249
            S + +E     + GE  DE DE  +    +++ QK K  P  E   EDDD
Sbjct: 170 NSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDD 220



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 31/100 (31%), Positives = 42/100 (42%), Gaps = 23/100 (23%)

Query: 172 EDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEE--GYNDGEV---------- 219
           E ++  E  E    VE  E    E+E     V  EEEED E  G +D E           
Sbjct: 459 ESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKV 518

Query: 220 -----------DDEEDEEELGEEERGQKRKREPEDEGEDD 248
                      + EE+EEE  EEE  ++ + E E+EGE +
Sbjct: 519 EGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESE 558



 Score = 36.2 bits (82), Expect = 0.027
 Identities = 23/106 (21%), Positives = 51/106 (48%), Gaps = 10/106 (9%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G  + +K+  D D +  ++ L++   +    + D +   V+  E+ +EE   +++   G+
Sbjct: 42  GKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQ 101

Query: 207 EEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDE---GEDDD 249
           + + +         D+ D EEL +++   K+  +P+ E   G DDD
Sbjct: 102 KGKKQSF-------DDNDSEELEDKDSKSKKTAKPKVEMYSGSDDD 140



 Score = 35.4 bits (80), Expect = 0.047
 Identities = 23/107 (21%), Positives = 53/107 (49%), Gaps = 16/107 (14%)

Query: 156 PDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEG----------------E 199
           P S+ +       +++ + D+++ D+  +  E EE E E+++G                +
Sbjct: 293 PASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLK 352

Query: 200 EEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGE 246
           EE+   + EE+E      E++ +  EEE  E+E+ +++K++ ++  E
Sbjct: 353 EEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKE 399



 Score = 35.0 bits (79), Expect = 0.061
 Identities = 24/109 (22%), Positives = 47/109 (43%), Gaps = 17/109 (15%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208
           ++++ E    D     E     EE+  + +   D  V+   E++ E     E+D  G+++
Sbjct: 255 EKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK 314

Query: 209 EDEEGYNDGEVDDEEDEEELG-----------------EEERGQKRKRE 240
           + ++    GE +++E E++ G                 EEE  QKR+ E
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 18/84 (21%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 168 DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEE--EEDEEGYNDGEVDDEEDE 225
           ++EEE   +++  +  +  +   D+++ EE E++D   ++  +   E Y+    DD++D 
Sbjct: 86  NNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGS--DDDDDF 143

Query: 226 EELGEEERGQKRKREPEDEGEDDD 249
            +L ++ +G+ +K   + +G ++D
Sbjct: 144 NKLPKKAKGKAQKSNKKWDGSEED 167



 Score = 30.8 bits (68), Expect = 1.2
 Identities = 22/102 (21%), Positives = 51/102 (50%), Gaps = 23/102 (22%)

Query: 155 APDSDAEGYVEGLDDEEEDEDEEEYDEDAQ--------------VVEDEEDEDEEEEGEE 200
           A + D EG  +  D +++  ++EE +++ +              + + +E+E+ ++  EE
Sbjct: 304 AAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE 363

Query: 201 EDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPE 242
           E +   EE + +          ++EE L +E+R +K+++E E
Sbjct: 364 ERIKRLEELEAK---------RKEEERLEQEKRERKKQKEKE 396



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 41/198 (20%), Positives = 81/198 (40%), Gaps = 23/198 (11%)

Query: 63  LNKLKKLELSDNRVSGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFN 122
           L +L++L L    +    E +A K           N  ++ ++ +  KK +  K     +
Sbjct: 59  LKELEELSLEAQGIKADRETVAVKPTE--------NNEEEFTSKDKKKKGQKGKKQSFDD 110

Query: 123 CEVTNLNDYRENVFKLL-PQLTYLDGYDRDDK-----EAPDSDAEGYVEGLDDEEEDEDE 176
            +   L D      K   P++    G D DD      +     A+   +  D  EEDED 
Sbjct: 111 NDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN 170

Query: 177 -EEYDEDAQVVEDEEDEDEEEE------GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELG 229
            ++  E +++    E  DE +E      G++++   +   + E  N  E DD   + +  
Sbjct: 171 SKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGN--EDDDASFKIKTV 228

Query: 230 EEERGQKRKREPEDEGED 247
            +++ +K++RE +   E+
Sbjct: 229 AQKKAEKKERERKKRDEE 246



 Score = 28.5 bits (62), Expect = 5.7
 Identities = 21/101 (20%), Positives = 47/101 (46%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208
           D  D +A  ++ EG     + E +    ++  E  +   DE+D  +E E    +  G + 
Sbjct: 15  DDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKA 74

Query: 209 EDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           + E        ++EE+     ++++GQK K++  D+ + ++
Sbjct: 75  DRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115



 Score = 28.5 bits (62), Expect = 5.7
 Identities = 37/163 (22%), Positives = 71/163 (43%), Gaps = 22/163 (13%)

Query: 20  KELVLDNSRSN---EGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRV 76
           K  +LD  R     +G+  G+T +      +   NV L +I    K+  +K  +  + R+
Sbjct: 644 KTKILDKLRHTHVQDGEAGGITQQ------IGATNVPLEAINEQTKM--IKNFDRENVRI 695

Query: 77  SGGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVF 136
            G L +      + ++L   G+ + D++ +     ++ +  L+    E  NL   ++   
Sbjct: 696 PGMLIIDTPGHESFSNLRNRGSSLCDIAILV----VDIMHGLEPQTIESINLLKSKK--- 748

Query: 137 KLLPQLTYLDGYDR--DDKEAPDSDAEGYVEGLDDEEEDEDEE 177
              P +  L+  DR  D K++PDSD    ++      +DE EE
Sbjct: 749 --CPFIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEE 789


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 37/81 (45%), Positives = 52/81 (64%), Gaps = 11/81 (13%)

Query: 169 DEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEEL 228
           DEEE+E+EE           EE+E+EEEE EEED   EEE++EE + + E ++EE EEE 
Sbjct: 887 DEEEEEEEE-----------EEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF 935

Query: 229 GEEERGQKRKREPEDEGEDDD 249
            EEE   + + E EDE E+++
Sbjct: 936 EEEEGELEEEEEEEDEEEEEE 956



 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 41/92 (44%), Positives = 57/92 (61%), Gaps = 9/92 (9%)

Query: 142 LTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE-EEEGEE 200
           LT ++    D++E  + + E   E  ++EEED +EEE DE+    E+EE+E+E EEE EE
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937

Query: 201 EDVSGEEEEDEEGYNDGEVDDEEDEEELGEEE 232
           E+   EEEE+EE        DEE+EEEL E E
Sbjct: 938 EEGELEEEEEEE--------DEEEEEELEEVE 961



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 30/73 (41%), Positives = 47/73 (64%), Gaps = 4/73 (5%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208
           + +D E  + D E Y E  ++EEE+ +EE  +E+ ++ E+EE+EDEEEE E E+V    E
Sbjct: 906 EEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV----E 961

Query: 209 EDEEGYNDGEVDD 221
           + E G   GEV++
Sbjct: 962 DLEFGTAGGEVEE 974


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 31/66 (46%), Positives = 47/66 (71%)

Query: 165 EGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEED 224
           EG ++EEE+E+EEE + + +  E+E +E+EEE GE E++  EEE +EEG  D + ++EED
Sbjct: 404 EGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED 463

Query: 225 EEELGE 230
           EE   E
Sbjct: 464 EESSSE 469



 Score = 64.3 bits (155), Expect = 9e-11
 Identities = 36/76 (47%), Positives = 49/76 (64%), Gaps = 6/76 (7%)

Query: 168 DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEE 227
           ++EEE+E+EEE +E     E+EE E+EEEEG E +  GEEEE EE   +G+VD +E+EE 
Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE---EGDVDSDEEEE- 461

Query: 228 LGEEERGQKRKREPED 243
             E+E       E ED
Sbjct: 462 --EDEESSSEGLEAED 475



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 30/66 (45%), Positives = 44/66 (66%), Gaps = 5/66 (7%)

Query: 186 VEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEE--DEEELGEEERGQKRKREPED 243
           ++ E +E+EEEE EEE+  GE EE+EE   +GE ++EE  + EELGEEE  ++      D
Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEGEEEEE---EGEEEEEEGGEGEELGEEEEVEEEGDVDSD 457

Query: 244 EGEDDD 249
           E E++D
Sbjct: 458 EEEEED 463



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 31/78 (39%), Positives = 48/78 (61%), Gaps = 11/78 (14%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEE-EGEEEDVSGEEEEDEEGYNDGEVDDEEDEEEL 228
           + E E+EEE         +EE+E+EEE EGEEE+  GEEEE+E G  + E+ +EE+ EE 
Sbjct: 402 KSEGEEEEE---------EEEEEEEEEGEGEEEEEEGEEEEEEGGEGE-ELGEEEEVEEE 451

Query: 229 GEEERGQKRKREPEDEGE 246
           G+ +  ++ + + E   E
Sbjct: 452 GDVDSDEEEEEDEESSSE 469



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 40/137 (29%), Positives = 63/137 (45%), Gaps = 41/137 (29%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEED---------EDEEE 196
           +G + +++E  + + EG  EG ++EEE E+EEE   + + + +EE+         ++EEE
Sbjct: 404 EGEEEEEEEEEEEEEEG--EGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461

Query: 197 EGEEEDVSGEEEED------------------EEG------YNDGEVDDEEDEEELGEEE 232
           E EE    G E ED                  EE       + +G  D + D EE  +EE
Sbjct: 462 EDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEE 521

Query: 233 RGQKRKREPEDEGEDDD 249
                  + EDE +DDD
Sbjct: 522 ------EDDEDEDDDDD 532



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 49/131 (37%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDED---------EEEYDEDAQVVEDEEDEDEEE--- 196
           + +++E  + + EG  E  + EEE+E+         EEE +E+  V  DEE+E++EE   
Sbjct: 409 EEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSS 468

Query: 197 ------------------------------------EGEEEDVSGEEEEDEEGYNDGEVD 220
                                               EG E+  S  EEED+E  +D + D
Sbjct: 469 EGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDED 528

Query: 221 DEEDEEELGEE 231
           D++DEE+ G+E
Sbjct: 529 DDDDEED-GDE 538



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 18/41 (43%), Positives = 29/41 (70%), Gaps = 2/41 (4%)

Query: 163 YVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDV 203
           ++EG   E+ D D EE D++ +  EDE+D+D+EE+G+E  V
Sbjct: 503 FLEG--GEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPV 541



 Score = 31.6 bits (70), Expect = 0.67
 Identities = 15/46 (32%), Positives = 28/46 (60%), Gaps = 3/46 (6%)

Query: 140 PQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQV 185
           P L +L+G +  D ++ + D E   E  D++E+D+D+EE  ++  V
Sbjct: 499 PTLHFLEGGEDSDSDSEEEDDE---EEDDEDEDDDDDEEDGDEVPV 541


>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
          Length = 466

 Score = 65.1 bits (157), Expect = 6e-11
 Identities = 61/216 (28%), Positives = 100/216 (46%), Gaps = 23/216 (10%)

Query: 33  KLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSGGLEVLAEKCPNLTH 92
           +LE +     +L+ L   N  +  I N+ KL KL+ L L+ N +   +E L E C  L  
Sbjct: 35  RLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEK-IENL-EGCEELAK 92

Query: 93  LNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDD 152
           L+L+ N I +LS+I+ L+   +LK L L      + + YRE V   LPQL +LDG + + 
Sbjct: 93  LDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQLKWLDGKEIEP 152

Query: 153 KEAPDSDAEGYVEGLDDEEEDED----EEEYDEDAQVVEDEEDEDEEEEGEE-------- 200
            E   +  +  V      E+++D      +  E+AQ    EED++E++            
Sbjct: 153 SERIKALQDYSVIEPQIREQEKDHCLKRAKLKEEAQRKHQEEDKNEDKRSNAGFDGRWYT 212

Query: 201 ---------EDVSGEEEEDEEGYNDGEVDDEEDEEE 227
                    E     +  D E +N  ++D+ ED+ E
Sbjct: 213 DINATLSSLESKDHLQAPDTEEHNTKKLDNSEDDLE 248


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 64.7 bits (156), Expect = 7e-11
 Identities = 41/99 (41%), Positives = 56/99 (56%), Gaps = 9/99 (9%)

Query: 152 DKEAPDSDAEGYVEGLDDEEEDEDE-EEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + E   SD E    G  DE+ +  E EE   +  V EDEE E++ EE EE D  GEEEE+
Sbjct: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234

Query: 211 EEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           EE        +EE+EEE  EEE  ++ +R+ ++EG D D
Sbjct: 235 EE--------EEEEEEEEEEEEEYEQDERDQKEEGNDYD 265



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 8/86 (9%)

Query: 171 EEDEDEEEYDEDAQVV------EDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDD--E 222
           +E+ + EEY  D +        E   + + EEEG EEDV  +EE +E+   D EVD+  E
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230

Query: 223 EDEEELGEEERGQKRKREPEDEGEDD 248
           E+EEE  EEE  ++ + E  ++ E D
Sbjct: 231 EEEEEEEEEEEEEEEEEEEYEQDERD 256



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           +++E  + D E   E  +D EEDE+ +E  E+ +  E+EE+E+EEEE EEE    E ++ 
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE-EEEYEQDERDQK 258

Query: 211 EEGYNDGEVDDEEDEEELGEE 231
           EEG    + D   +  + G E
Sbjct: 259 EEG---NDYDTRSEASDSGSE 276



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 9/98 (9%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEE----DEDEEEEGEEEDVS 204
           D ++ E  + DAE   E  +D EE+E+EEE +E+ +  E+EE    + D++EEG + D  
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTR 267

Query: 205 GEEEE---DEEGYNDGEVDDEEDEEELGEEERGQKRKR 239
            E  +   +   + DG V      +  G +E+ ++RKR
Sbjct: 268 SEASDSGSESVSFTDGSVRSGSGTD--GSDEKKKERKR 303



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 27/119 (22%), Positives = 52/119 (43%), Gaps = 5/119 (4%)

Query: 136 FKLLPQLTYLDGYDRDDK-EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE 194
           +K  P+ T +   D + + ++P  D    +    D       +   E+    E   D + 
Sbjct: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHET 185

Query: 195 EEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEER----GQKRKREPEDEGEDDD 249
              G  ++     E +EEG  +   +DEE EE+  E+E     G++ + E E+E E+++
Sbjct: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 64.7 bits (156), Expect = 7e-11
 Identities = 66/232 (28%), Positives = 113/232 (48%), Gaps = 7/232 (3%)

Query: 19  VKELVLDNSRSNEGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSG 78
           VK  VL+ S +  GK+E L D+  +L  L+     ++ I  +  +  L+KL L+ N +  
Sbjct: 125 VKLEVLNLSYNLIGKIEKL-DKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEH 183

Query: 79  GLEVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLNDYRENVFKL 138
               L +K  +L  LNL GNKI  L  I  LK L++L SL L    V  L  Y +     
Sbjct: 184 IPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFH 243

Query: 139 LPQLTYLDGY---DRDDKEAPDSDAEGYVEGLDDEEED---EDEEEYDEDAQVVEDEEDE 192
           L  L  L+G     +D +EA +  +   VE L+ + E    E EE   +  + +E+ +++
Sbjct: 244 LRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQ 303

Query: 193 DEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDE 244
           D+  +  +E+   +++  EE  +D    +E  +++  E  R  +++ E E E
Sbjct: 304 DKLNKSLKEEAMLQKQSCEELKSDLNTKNELLKQKTIELTRACQKQYELEQE 355


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 64.7 bits (156), Expect = 7e-11
 Identities = 41/99 (41%), Positives = 56/99 (56%), Gaps = 9/99 (9%)

Query: 152 DKEAPDSDAEGYVEGLDDEEEDEDE-EEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + E   SD E    G  DE+ +  E EE   +  V EDEE E++ EE EE D  GEEEE+
Sbjct: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234

Query: 211 EEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           EE        +EE+EEE  EEE  ++ +R+ ++EG D D
Sbjct: 235 EE--------EEEEEEEEEEEEEYEQDERDQKEEGNDYD 265



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 32/86 (37%), Positives = 48/86 (55%), Gaps = 8/86 (9%)

Query: 171 EEDEDEEEYDEDAQVV------EDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDD--E 222
           +E+ + EEY  D +        E   + + EEEG EEDV  +EE +E+   D EVD+  E
Sbjct: 171 KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230

Query: 223 EDEEELGEEERGQKRKREPEDEGEDD 248
           E+EEE  EEE  ++ + E  ++ E D
Sbjct: 231 EEEEEEEEEEEEEEEEEEEYEQDERD 256



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 29/81 (35%), Positives = 46/81 (56%), Gaps = 4/81 (4%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           +++E  + D E   E  +D EEDE+ +E  E+ +  E+EE+E+EEEE EEE    E ++ 
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE-EEEYEQDERDQK 258

Query: 211 EEGYNDGEVDDEEDEEELGEE 231
           EEG    + D   +  + G E
Sbjct: 259 EEG---NDYDTRSEASDSGSE 276



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 9/98 (9%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEE----DEDEEEEGEEEDVS 204
           D ++ E  + DAE   E  +D EE+E+EEE +E+ +  E+EE    + D++EEG + D  
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTR 267

Query: 205 GEEEE---DEEGYNDGEVDDEEDEEELGEEERGQKRKR 239
            E  +   +   + DG V      +  G +E+ ++RKR
Sbjct: 268 SEASDSGSESVSFTDGSVRSGSGTD--GSDEKKKERKR 303



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 27/119 (22%), Positives = 52/119 (43%), Gaps = 5/119 (4%)

Query: 136 FKLLPQLTYLDGYDRDDK-EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDE 194
           +K  P+ T +   D + + ++P  D    +    D       +   E+    E   D + 
Sbjct: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHET 185

Query: 195 EEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEER----GQKRKREPEDEGEDDD 249
              G  ++     E +EEG  +   +DEE EE+  E+E     G++ + E E+E E+++
Sbjct: 186 GSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 40/113 (35%), Positives = 58/113 (51%), Gaps = 23/113 (20%)

Query: 160 AEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEE-------------EDVSGE 206
           A+G   G + ++ED DEEE D+  +  ED+EDEDE+E+  E             ED   E
Sbjct: 131 AKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDE 190

Query: 207 EEEDEEGYNDGEVDDEEDEEELGEEERGQKRKR----------EPEDEGEDDD 249
           ++ED+E  +D E DD E+E       +G+K  +          E EDE EDD+
Sbjct: 191 DDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDE 243



 Score = 61.6 bits (148), Expect = 6e-10
 Identities = 36/102 (35%), Positives = 60/102 (58%), Gaps = 18/102 (17%)

Query: 155 APDSDAEGYVEGLDDEEEDEDEEEYDED-------------AQVVEDE-----EDEDEEE 196
           AP S+ E   +  DDE++D+DEE+  E+             A+VV  +     EDEDEEE
Sbjct: 181 APASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEE 240

Query: 197 EGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRK 238
           + E+ED   +E+++++   D E ++EE+EEE  +E  G+++K
Sbjct: 241 DDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKK 282



 Score = 58.9 bits (141), Expect = 4e-09
 Identities = 40/122 (32%), Positives = 61/122 (50%), Gaps = 26/122 (21%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVV-------EDEEDEDEEEEGEEEDV 203
           D  E  D D+E   E  DDE+EDEDE+E +  A          EDE+DED+E++ E++D 
Sbjct: 144 DSDEEEDDDSEEDEE--DDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDD-EDDDD 200

Query: 204 SGEEEEDEEGYND----------------GEVDDEEDEEELGEEERGQKRKREPEDEGED 247
             E++ +EE                      V ++EDEEE  E+E     + + +D+ ED
Sbjct: 201 DEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDED 260

Query: 248 DD 249
           D+
Sbjct: 261 DE 262



 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 22/114 (19%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG--- 205
           D D+ E     A       +DE++++DE++ D+D    +DEED+ EEE  E     G   
Sbjct: 166 DEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDD----DDEEDDSEEEAMETTPAKGKKA 221

Query: 206 ---------------EEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDE 244
                          +EEED+E  +D + +D+ED+++  +EE  ++ + EP  E
Sbjct: 222 AKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKE 275



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 19/107 (17%)

Query: 146 DGYDRDDKEAPDSDAEGY----VEG----------LDDEEEDEDEEEYDEDAQVVEDEED 191
           D  D DD E  DS+ E       +G            +  EDEDEEE DED    +D++D
Sbjct: 194 DDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDE---DDDDD 250

Query: 192 EDEEEEGEEEDVSGEEEEDEEGYND--GEVDDEEDEEELGEEERGQK 236
           ED+E++ +E+D   EEEE+EE   +  G+   E  +++   E + QK
Sbjct: 251 EDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297



 Score = 37.0 bits (84), Expect = 0.016
 Identities = 17/65 (26%), Positives = 39/65 (60%), Gaps = 3/65 (4%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEE 208
           + DD++  D D E   +  DD++ED++EEE +E+ + V++   + ++E  +++     ++
Sbjct: 239 EEDDEDEDDDDDE---DDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKK 295

Query: 209 EDEEG 213
           +  EG
Sbjct: 296 QKVEG 300



 Score = 31.2 bits (69), Expect = 0.88
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 2/61 (3%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEE--DEDEEEEGEEEDVSGE 206
           D D+ +  D D E   +  D+EEE+E+EEE  ++A     +E   +    E +++ V G 
Sbjct: 242 DEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGT 301

Query: 207 E 207
           E
Sbjct: 302 E 302



 Score = 28.5 bits (62), Expect = 5.7
 Identities = 11/22 (50%), Positives = 17/22 (77%)

Query: 186 VEDEEDEDEEEEGEEEDVSGEE 207
           VE++ +++E  E EE+D SGEE
Sbjct: 24  VEEDSEDEEMSEDEEDDSSGEE 45


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%)

Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197
           LL  L  +   +R    A  S AE    G   EEE+E+EEE +E+    E+ E+E+EEEE
Sbjct: 250 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 306

Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
            EEE+     EE            E+  EE+ EEE  +  +RE E+
Sbjct: 307 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 342



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221
           +EE  +E +   D Q + D E +    E        G EE+   EEEE+EEG    E ++
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300

Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247
           EE+EEE  EEE G   +   E   E+
Sbjct: 301 EEEEEEEEEEETGSNSEEASEQSAEE 326



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G + +++E  + + EG     + EEE+E+EEE +E+     +E  E   EE  EE++S +
Sbjct: 277 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 335

Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235
           EE + E +     +   D +  E E  EEE G+
Sbjct: 336 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 368



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + +EA +  AE   E  ++  EDE+ E  +    V E   D D  E  E E+  GE    
Sbjct: 315 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 372

Query: 211 EEGYNDGE 218
                +G+
Sbjct: 373 SSALTEGD 380



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236
           E  +  + V++E+ E+ +   + +D+S  E +     +   E     +EEE  EEE  ++
Sbjct: 232 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 291

Query: 237 RKREPEDEGEDDD 249
                E E E+++
Sbjct: 292 GSTSEESEEEEEE 304



 Score = 27.7 bits (60), Expect = 9.7
 Identities = 18/76 (23%), Positives = 38/76 (50%), Gaps = 1/76 (1%)

Query: 172 EDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEE 231
           +DE  +E  + A+V E  E E  +   EE+D +  E E ++           + + L + 
Sbjct: 101 KDEKRKEKWKHARVKE-REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQL 159

Query: 232 ERGQKRKREPEDEGED 247
           ER ++R+R+  ++ ++
Sbjct: 160 ERKRERERKMREQQKE 175


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%)

Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197
           LL  L  +   +R    A  S AE    G   EEE+E+EEE +E+    E+ E+E+EEEE
Sbjct: 260 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 316

Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
            EEE+     EE            E+  EE+ EEE  +  +RE E+
Sbjct: 317 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 352



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221
           +EE  +E +   D Q + D E +    E        G EE+   EEEE+EEG    E ++
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310

Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247
           EE+EEE  EEE G   +   E   E+
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEE 336



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G + +++E  + + EG     + EEE+E+EEE +E+     +E  E   EE  EE++S +
Sbjct: 287 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345

Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235
           EE + E +     +   D +  E E  EEE G+
Sbjct: 346 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 378



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + +EA +  AE   E  ++  EDE+ E  +    V E   D D  E  E E+  GE    
Sbjct: 325 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 382

Query: 211 EEGYNDGE 218
                +G+
Sbjct: 383 SSALTEGD 390



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236
           E  +  + V++E+ E+ +   + +D+S  E +     +   E     +EEE  EEE  ++
Sbjct: 242 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 301

Query: 237 RKREPEDEGEDDD 249
                E E E+++
Sbjct: 302 GSTSEESEEEEEE 314


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 32/73 (43%), Positives = 47/73 (64%)

Query: 168 DDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEE 227
           +DEEE+E+EEE +ED +  E+EE+E+EEEE EEE+   EEEE+EE     +V  +ED   
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319

Query: 228 LGEEERGQKRKRE 240
              ++  + R  E
Sbjct: 320 TSAQKAPELRGPE 332



 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 32/61 (52%), Positives = 42/61 (68%), Gaps = 9/61 (14%)

Query: 167 LDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEE 226
           L  EEEDE+EEE +E+ +  E+EE+E+EEEE EEE+   EEEE+EE         EE+EE
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE---------EEEEE 305

Query: 227 E 227
           E
Sbjct: 306 E 306



 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 29/68 (42%), Positives = 44/68 (64%)

Query: 165 EGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEED 224
           + L+D   +E  ++    +   EDEE+E+EEEE EE++   EEEE+EE   + E ++EE+
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297

Query: 225 EEELGEEE 232
           EEE  EEE
Sbjct: 298 EEEEEEEE 305



 Score = 57.8 bits (138), Expect = 9e-09
 Identities = 31/92 (33%), Positives = 51/92 (55%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           +D  + +S  +  +   ++E+E+E+EEE +E+    E+EE+E+EEEE EEE+   EEEE+
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300

Query: 211 EEGYNDGEVDDEEDEEELGEEERGQKRKREPE 242
           EE   +   D    E+      +     R PE
Sbjct: 301 EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPE 332



 Score = 57.0 bits (136), Expect = 1e-08
 Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 1/77 (1%)

Query: 172 EDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEE 231
           ED   EE  +   ++  EE EDEEEE EEE+   +EEE+EE   + E ++EE+EEE  EE
Sbjct: 241 EDAASEESSKQKGILSHEE-EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299

Query: 232 ERGQKRKREPEDEGEDD 248
           E  ++ +  P+   ++D
Sbjct: 300 EEEEEEEAAPDVIFQED 316



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 12/94 (12%)

Query: 163 YVEGLDDEEEDEDEEEYDEDA--QVVEDEEDEDEEEEG-----EEEDVSGEEEEDEEGYN 215
           +++  D EE  E   E  +D   Q +ED   E+  ++      EEED   EEEE+EE   
Sbjct: 215 FIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEE--- 271

Query: 216 DGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
             E D+EE+EEE  EEE  ++ + E E+E E+++
Sbjct: 272 --EEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303



 Score = 47.8 bits (112), Expect = 9e-06
 Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 13/115 (11%)

Query: 148 YDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEE 207
           ++ +D+E  + + E   +  ++EEE+E+EEE +E+ +  E+EE+E+EEEE   + +  E+
Sbjct: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316

Query: 208 EEDEEGYNDGEVDDEEDEEELGE-------------EERGQKRKREPEDEGEDDD 249
                     E+   E      E             +E    RK    DE E  D
Sbjct: 317 TSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQD 371



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 24/63 (38%), Positives = 39/63 (61%), Gaps = 7/63 (11%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205
           D  + +++E  + D E   E  ++EEE+E+EEE +E     E+EE+E+EEEE    DV  
Sbjct: 261 DEEEEEEEEEEEEDEEEEEE--EEEEEEEEEEEEEE-----EEEEEEEEEEEEAAPDVIF 313

Query: 206 EEE 208
           +E+
Sbjct: 314 QED 316



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 4/87 (4%)

Query: 165 EGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEE--EDVSGEEEEDEEGYNDGEVDDE 222
           EG   EE ++      EDA+ V +   E  ++   +  ED + EE   ++G    E +DE
Sbjct: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262

Query: 223 EDEEELGEEERGQKRKREPEDEGEDDD 249
           E  EE  EEE  +  + E E+E E+++
Sbjct: 263 E--EEEEEEEEEEDEEEEEEEEEEEEE 287


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%)

Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197
           LL  L  +   +R    A  S AE    G   EEE+E+EEE +E+    E+ E+E+EEEE
Sbjct: 251 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 307

Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
            EEE+     EE            E+  EE+ EEE  +  +RE E+
Sbjct: 308 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 343



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221
           +EE  +E +   D Q + D E +    E        G EE+   EEEE+EEG    E ++
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 301

Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247
           EE+EEE  EEE G   +   E   E+
Sbjct: 302 EEEEEEEEEEETGSNSEEASEQSAEE 327



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G + +++E  + + EG     + EEE+E+EEE +E+     +E  E   EE  EE++S +
Sbjct: 278 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 336

Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235
           EE + E +     +   D +  E E  EEE G+
Sbjct: 337 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 369



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + +EA +  AE   E  ++  EDE+ E  +    V E   D D  E  E E+  GE    
Sbjct: 316 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 373

Query: 211 EEGYNDGE 218
                +G+
Sbjct: 374 SSALTEGD 381



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236
           E  +  + V++E+ E+ +   + +D+S  E +     +   E     +EEE  EEE  ++
Sbjct: 233 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 292

Query: 237 RKREPEDEGEDDD 249
                E E E+++
Sbjct: 293 GSTSEESEEEEEE 305


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%)

Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197
           LL  L  +   +R    A  S AE    G   EEE+E+EEE +E+    E+ E+E+EEEE
Sbjct: 260 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 316

Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
            EEE+     EE            E+  EE+ EEE  +  +RE E+
Sbjct: 317 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 352



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221
           +EE  +E +   D Q + D E +    E        G EE+   EEEE+EEG    E ++
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310

Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247
           EE+EEE  EEE G   +   E   E+
Sbjct: 311 EEEEEEEEEEETGSNSEEASEQSAEE 336



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G + +++E  + + EG     + EEE+E+EEE +E+     +E  E   EE  EE++S +
Sbjct: 287 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 345

Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235
           EE + E +     +   D +  E E  EEE G+
Sbjct: 346 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 378



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + +EA +  AE   E  ++  EDE+ E  +    V E   D D  E  E E+  GE    
Sbjct: 325 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 382

Query: 211 EEGYNDGE 218
                +G+
Sbjct: 383 SSALTEGD 390



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236
           E  +  + V++E+ E+ +   + +D+S  E +     +   E     +EEE  EEE  ++
Sbjct: 242 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 301

Query: 237 RKREPEDEGEDDD 249
                E E E+++
Sbjct: 302 GSTSEESEEEEEE 314


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%)

Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197
           LL  L  +   +R    A  S AE    G   EEE+E+EEE +E+    E+ E+E+EEEE
Sbjct: 228 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 284

Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
            EEE+     EE            E+  EE+ EEE  +  +RE E+
Sbjct: 285 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 320



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221
           +EE  +E +   D Q + D E +    E        G EE+   EEEE+EEG    E ++
Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 278

Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247
           EE+EEE  EEE G   +   E   E+
Sbjct: 279 EEEEEEEEEEETGSNSEEASEQSAEE 304



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G + +++E  + + EG     + EEE+E+EEE +E+     +E  E   EE  EE++S +
Sbjct: 255 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 313

Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235
           EE + E +     +   D +  E E  EEE G+
Sbjct: 314 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 346



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + +EA +  AE   E  ++  EDE+ E  +    V E   D D  E  E E+  GE    
Sbjct: 293 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 350

Query: 211 EEGYNDGE 218
                +G+
Sbjct: 351 SSALTEGD 358



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236
           E  +  + V++E+ E+ +   + +D+S  E +     +   E     +EEE  EEE  ++
Sbjct: 210 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 269

Query: 237 RKREPEDEGEDDD 249
                E E E+++
Sbjct: 270 GSTSEESEEEEEE 282


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%)

Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197
           LL  L  +   +R    A  S AE    G   EEE+E+EEE +E+    E+ E+E+EEEE
Sbjct: 217 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 273

Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
            EEE+     EE            E+  EE+ EEE  +  +RE E+
Sbjct: 274 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 309



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221
           +EE  +E +   D Q + D E +    E        G EE+   EEEE+EEG    E ++
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 267

Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247
           EE+EEE  EEE G   +   E   E+
Sbjct: 268 EEEEEEEEEEETGSNSEEASEQSAEE 293



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G + +++E  + + EG     + EEE+E+EEE +E+     +E  E   EE  EE++S +
Sbjct: 244 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 302

Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235
           EE + E +     +   D +  E E  EEE G+
Sbjct: 303 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 335



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + +EA +  AE   E  ++  EDE+ E  +    V E   D D  E  E E+  GE    
Sbjct: 282 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 339

Query: 211 EEGYNDGE 218
                +G+
Sbjct: 340 SSALTEGD 347



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236
           E  +  + V++E+ E+ +   + +D+S  E +     +   E     +EEE  EEE  ++
Sbjct: 199 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 258

Query: 237 RKREPEDEGEDDD 249
                E E E+++
Sbjct: 259 GSTSEESEEEEEE 271


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%)

Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197
           LL  L  +   +R    A  S AE    G   EEE+E+EEE +E+    E+ E+E+EEEE
Sbjct: 6   LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 62

Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
            EEE+     EE            E+  EE+ EEE  +  +RE E+
Sbjct: 63  EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 98



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G + +++E  + + EG     + EEE+E+EEE +E+     +E  E   EE  EE++S +
Sbjct: 33  GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 91

Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235
           EE + E +     +   D +  E E  EEE G+
Sbjct: 92  EERENENHLLVVPESRFDRDSGESEEAEEEVGE 124



 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 30/81 (37%), Positives = 39/81 (48%), Gaps = 5/81 (6%)

Query: 167 LDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEE 226
           L D ++  D E     A+    E     EEE EEE     EEE+EEG    E ++EE+EE
Sbjct: 7   LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE-----EEEEEEGSTSEESEEEEEEE 61

Query: 227 ELGEEERGQKRKREPEDEGED 247
           E  EEE G   +   E   E+
Sbjct: 62  EEEEEETGSNSEEASEQSAEE 82



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + +EA +  AE   E  ++  EDE+ E  +    V E   D D  E  E E+  GE    
Sbjct: 71  NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 128

Query: 211 EEGYNDGE 218
                +G+
Sbjct: 129 SSALTEGD 136


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 38/106 (35%), Positives = 53/106 (50%), Gaps = 13/106 (12%)

Query: 138 LLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE 197
           LL  L  +   +R    A  S AE    G   EEE+E+EEE +E+    E+ E+E+EEEE
Sbjct: 262 LLSDLQDISDSERKTSSAESSSAES---GSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 318

Query: 198 GEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPED 243
            EEE+     EE            E+  EE+ EEE  +  +RE E+
Sbjct: 319 EEEEETGSNSEE----------ASEQSAEEVSEEEMSEDEERENEN 354



 Score = 52.0 bits (123), Expect = 5e-07
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 8/86 (9%)

Query: 170 EEEDEDEEEYDEDAQVVEDEEDEDEEEE--------GEEEDVSGEEEEDEEGYNDGEVDD 221
           +EE  +E +   D Q + D E +    E        G EE+   EEEE+EEG    E ++
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 312

Query: 222 EEDEEELGEEERGQKRKREPEDEGED 247
           EE+EEE  EEE G   +   E   E+
Sbjct: 313 EEEEEEEEEEETGSNSEEASEQSAEE 338



 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 5/93 (5%)

Query: 147 GYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGE 206
           G + +++E  + + EG     + EEE+E+EEE +E+     +E  E   EE  EE++S +
Sbjct: 289 GSEEEEEEEEEEEEEGSTSE-ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED 347

Query: 207 EEEDEEGY----NDGEVDDEEDEEELGEEERGQ 235
           EE + E +     +   D +  E E  EEE G+
Sbjct: 348 EERENENHLLVVPESRFDRDSGESEEAEEEVGE 380



 Score = 31.6 bits (70), Expect = 0.67
 Identities = 19/83 (22%), Positives = 39/83 (46%), Gaps = 2/83 (2%)

Query: 167 LDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEE 226
           + DE++    +  DE  Q  +  ++++E+ E +    S + +   +   +GE+ D   E 
Sbjct: 1   MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI 60

Query: 227 ELGEEERGQKRKREPEDEGEDDD 249
            +       +R+   ED GE+DD
Sbjct: 61  TIRNSP--YRREDSMEDRGEEDD 81



 Score = 29.6 bits (65), Expect = 2.6
 Identities = 19/68 (27%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 151 DDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEED 210
           + +EA +  AE   E  ++  EDE+ E  +    V E   D D  E  E E+  GE    
Sbjct: 327 NSEEASEQSAEEVSE--EEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQ 384

Query: 211 EEGYNDGE 218
                +G+
Sbjct: 385 SSALTEGD 392



 Score = 28.9 bits (63), Expect = 4.4
 Identities = 17/73 (23%), Positives = 35/73 (47%), Gaps = 1/73 (1%)

Query: 178 EYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDG-EVDDEEDEEELGEEERGQK 236
           E  +  + V++E+ E+ +   + +D+S  E +     +   E     +EEE  EEE  ++
Sbjct: 244 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 303

Query: 237 RKREPEDEGEDDD 249
                E E E+++
Sbjct: 304 GSTSEESEEEEEE 316


>gi|11545835 TSPY-like 2 [Homo sapiens]
          Length = 693

 Score = 62.4 bits (150), Expect = 4e-10
 Identities = 49/205 (23%), Positives = 85/205 (41%), Gaps = 29/205 (14%)

Query: 65  KLKKLELSDNRVSGGLEV-LAEKCPNLTHLNLSGNKIKDLS-TIEPLKKLENLKSLDLFN 122
           K KK E+   +  G  EV + E  P+   +    ++I D+  TI  +K  + +++ D F 
Sbjct: 404 KRKKQEMKKRKTRGRCEVVIMEDAPDYYAVEDIFSEISDIDETIHDIKISDFMETTDYFE 463

Query: 123 CEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDED 182
                + D  EN+          D  + D  E P+++     E  DD E  ++ E  D++
Sbjct: 464 TTDNEITDINENI---------CDSENPDHNEVPNNETTDNNESADDHETTDNNESADDN 514

Query: 183 AQVVEDEE---DEDEEEEGEEEDVSG---------------EEEEDEEGYNDGEVDDEED 224
            +  ED     D++EE     E+  G               ++  D +   D   DDE++
Sbjct: 515 NENPEDNNKNTDDNEENPNNNENTYGNNFFKGGFWGSHGNNQDSSDSDNEADEASDDEDN 574

Query: 225 EEELGEEERGQKRKREPEDEGEDDD 249
           +   G+ E       E ++EG DDD
Sbjct: 575 DGNEGDNEGSDDDGNEGDNEGSDDD 599



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 36/104 (34%), Positives = 57/104 (54%), Gaps = 9/104 (8%)

Query: 146 DGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSG 205
           DG + D++ + D   EG  EG DD+  D D E Y+   +V+ED  D+D+ +  +  ++  
Sbjct: 575 DGNEGDNEGSDDDGNEGDNEGSDDD--DRDIEYYE---KVIED-FDKDQADYEDVIEIIS 628

Query: 206 EEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPEDEGEDDD 249
           +E  +EEG  +G   DE+  EE   EE G +   +  +EGED D
Sbjct: 629 DESVEEEGIEEGIQQDEDIYEEGNYEEEGSE---DVWEEGEDSD 669



 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 28/93 (30%), Positives = 53/93 (56%), Gaps = 9/93 (9%)

Query: 149 DRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEE-EEG--EEEDV-- 203
           D +  +  D D E Y + ++D   D+D+ +Y++  +++ DE  E+E  EEG  ++ED+  
Sbjct: 592 DNEGSDDDDRDIEYYEKVIED--FDKDQADYEDVIEIISDESVEEEGIEEGIQQDEDIYE 649

Query: 204 --SGEEEEDEEGYNDGEVDDEEDEEELGEEERG 234
             + EEE  E+ + +GE  D+ D E++ +   G
Sbjct: 650 EGNYEEEGSEDVWEEGEDSDDSDLEDVLQVPNG 682


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.131    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,006,661
Number of Sequences: 37866
Number of extensions: 690951
Number of successful extensions: 52009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1313
Number of HSP's successfully gapped in prelim test: 657
Number of HSP's that attempted gapping in prelim test: 6454
Number of HSP's gapped (non-prelim): 17864
length of query: 249
length of database: 18,247,518
effective HSP length: 100
effective length of query: 149
effective length of database: 14,460,918
effective search space: 2154676782
effective search space used: 2154676782
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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