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Search of human proteins with 5453830
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453830 origin recognition complex, subunit 2 [Homo sapiens]
(577 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453830 origin recognition complex, subunit 2 [Homo sapiens] 1137 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 46 8e-05
gi|10880975 hypothetical protein LOC57821 [Homo sapiens] 41 0.003
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 40 0.006
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 40 0.006
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] 38 0.029
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 38 0.029
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] 38 0.029
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 38 0.029
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 37 0.049
gi|38373673 synaptonemal complex protein 2 [Homo sapiens] 37 0.065
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 36 0.084
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 36 0.084
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 36 0.084
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 36 0.084
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 36 0.084
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 36 0.084
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 36 0.084
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 36 0.11
gi|37675268 zinc finger protein 200 isoform 2 [Homo sapiens] 35 0.19
gi|14165274 golgi-associated microtubule-binding protein HOOK3 [... 35 0.19
gi|45439327 periplakin [Homo sapiens] 35 0.19
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa... 35 0.25
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 35 0.25
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 35 0.25
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] 35 0.25
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 35 0.25
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 35 0.25
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 34 0.42
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 34 0.42
>gi|5453830 origin recognition complex, subunit 2 [Homo sapiens]
Length = 577
Score = 1137 bits (2940), Expect = 0.0
Identities = 577/577 (100%), Positives = 577/577 (100%)
Query: 1 MSKPELKEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEED 60
MSKPELKEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEED
Sbjct: 1 MSKPELKEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEED 60
Query: 61 DQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKS 120
DQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKS
Sbjct: 61 DQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKS 120
Query: 121 VSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSE 180
VSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSE
Sbjct: 121 VSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSE 180
Query: 181 SEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLV 240
SEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLV
Sbjct: 181 SEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLV 240
Query: 241 EEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYEKLFHK 300
EEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYEKLFHK
Sbjct: 241 EEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYEKLFHK 300
Query: 301 WMLQLHLGFNIVLYGLGSKRDLLERFRTTMLQDSIHVVINGFFPGISVKSVLNSITEEVL 360
WMLQLHLGFNIVLYGLGSKRDLLERFRTTMLQDSIHVVINGFFPGISVKSVLNSITEEVL
Sbjct: 301 WMLQLHLGFNIVLYGLGSKRDLLERFRTTMLQDSIHVVINGFFPGISVKSVLNSITEEVL 360
Query: 361 DHMGTFRSILDQLDWIVNKFKEDSSLELFLLIHNLDSQMLRGEKSQQIIGQLSSLHNIYL 420
DHMGTFRSILDQLDWIVNKFKEDSSLELFLLIHNLDSQMLRGEKSQQIIGQLSSLHNIYL
Sbjct: 361 DHMGTFRSILDQLDWIVNKFKEDSSLELFLLIHNLDSQMLRGEKSQQIIGQLSSLHNIYL 420
Query: 421 IASIDHLNAPLMWDHAKQSLFNWLWYETTTYSPYTEETSYENSLLVKQSGSLPLSSLTHV 480
IASIDHLNAPLMWDHAKQSLFNWLWYETTTYSPYTEETSYENSLLVKQSGSLPLSSLTHV
Sbjct: 421 IASIDHLNAPLMWDHAKQSLFNWLWYETTTYSPYTEETSYENSLLVKQSGSLPLSSLTHV 480
Query: 481 LRSLTPNARGIFRLLIKYQLDNQDNPSYIGLSFQDFYQQCREAFLVNSDLTLRAQLTEFR 540
LRSLTPNARGIFRLLIKYQLDNQDNPSYIGLSFQDFYQQCREAFLVNSDLTLRAQLTEFR
Sbjct: 481 LRSLTPNARGIFRLLIKYQLDNQDNPSYIGLSFQDFYQQCREAFLVNSDLTLRAQLTEFR 540
Query: 541 DHKLIRTKKGTDGVEYLLIPVDNGTLTDFLEKEEEEA 577
DHKLIRTKKGTDGVEYLLIPVDNGTLTDFLEKEEEEA
Sbjct: 541 DHKLIRTKKGTDGVEYLLIPVDNGTLTDFLEKEEEEA 577
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 46.2 bits (108), Expect = 8e-05
Identities = 59/290 (20%), Positives = 130/290 (44%), Gaps = 15/290 (5%)
Query: 28 DREGGAKLKKERAQLLVNPKKIIKKPEYDLEE--DDQEVLKDQNYVEIMGRD--VQESLK 83
D E + ++ER Q+L N KK ++ DLEE D++E + + +E + + +++ +
Sbjct: 926 DLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEE 985
Query: 84 NGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSFS-LKNDPEITINVPQSSKGH 142
N + + + +++A+ +S+LA+ +K+ + + ++N E+ I+ +
Sbjct: 986 EILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS--DLEERL 1043
Query: 143 SASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDT 202
+K + + L L+ ++ ++ D A E+ +G +++T
Sbjct: 1044 KKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDET 1103
Query: 203 ----NAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRT 258
NA+ +++QAQ + E S+ + DL EE EA + T D T
Sbjct: 1104 LHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEE-LEALKTELEDTLDTT 1162
Query: 259 -LQKLKRAKLDQQT--LRNLLSKVSPSFSAELKQLNQQYEKLFHKWMLQL 305
Q+ R K +Q+ L+ L + + + A+++ + Q++ + QL
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212
>gi|10880975 hypothetical protein LOC57821 [Homo sapiens]
Length = 508
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 9/139 (6%)
Query: 103 SEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQ-SSKGHSASDKVQPKNNDKSEFLST 161
+EK E+A +++++ LK + + + + S S D+V P+ ND
Sbjct: 30 NEKSDASIIEMACEKEENINQDLKENETVMEHTKRHSDPDKSLQDEVSPRRNDIISVPGI 89
Query: 162 APRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVS-A 220
P + P S SDSE+ + S E + + +E +E+ I + +QA + +
Sbjct: 90 QP-------LDPISDSDSENSFQESKLESQKDLEEEEDEEVRRYIMEKIVQANKLLQNQE 142
Query: 221 PVGKETPSKRMKRDKTSDL 239
PV + K +D+ DL
Sbjct: 143 PVNDKRERKLKFKDQLVDL 161
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 40.0 bits (92), Expect = 0.006
Identities = 55/262 (20%), Positives = 100/262 (38%), Gaps = 31/262 (11%)
Query: 40 AQLLVNPKKIIKKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQN 99
+QLL +P + I + EEDD+ L D N +E + D E+ N TG Q
Sbjct: 257 SQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTEN-SNSRDTG------LSQP 309
Query: 100 RKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFL 159
R+ S+ Q+ +L + ++ P S A+ Q +++ E +
Sbjct: 310 RRDSK----------GDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEV 359
Query: 160 STAPR----SLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQN 215
+ R + + SDS E S+ + ++E + D+ + S+ +
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSES---SESLNFSE 416
Query: 216 RVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNL 275
+P + + S+ + +S + E+HS D Q R+K D +
Sbjct: 417 ESPESPEDENSSSQEGLQSHSSSAESQSEESHSEE----DDSDSQDSSRSKEDSNSTE-- 470
Query: 276 LSKVSPSFSAELKQLNQQYEKL 297
SK S +LK + + KL
Sbjct: 471 -SKSSSEEDGQLKNIEIESRKL 491
Score = 30.8 bits (68), Expect = 3.5
Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 6/92 (6%)
Query: 177 SDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKT 236
SD ES + + DDEG+ + E + + +R+ SA + + + ++ T
Sbjct: 198 SDGESSHGDGSELDDEGMQSDDPESIRSE------RGNSRMNSAGMKSKESGENSEQANT 251
Query: 237 SDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLD 268
D H S K+ R ++ R++LD
Sbjct: 252 QDSGGSQLLEHPSRKIFRKSRISEEDDRSELD 283
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 40.0 bits (92), Expect = 0.006
Identities = 55/262 (20%), Positives = 100/262 (38%), Gaps = 31/262 (11%)
Query: 40 AQLLVNPKKIIKKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQN 99
+QLL +P + I + EEDD+ L D N +E + D E+ N TG Q
Sbjct: 241 SQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTEN-SNSRDTG------LSQP 293
Query: 100 RKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFL 159
R+ S+ Q+ +L + ++ P S A+ Q +++ E +
Sbjct: 294 RRDSK----------GDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEV 343
Query: 160 STAPR----SLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQN 215
+ R + + SDS E S+ + ++E + D+ + S+ +
Sbjct: 344 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSES---SESLNFSE 400
Query: 216 RVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNL 275
+P + + S+ + +S + E+HS D Q R+K D +
Sbjct: 401 ESPESPEDENSSSQEGLQSHSSSAESQSEESHSEE----DDSDSQDSSRSKEDSNSTE-- 454
Query: 276 LSKVSPSFSAELKQLNQQYEKL 297
SK S +LK + + KL
Sbjct: 455 -SKSSSEEDGQLKNIEIESRKL 475
Score = 30.8 bits (68), Expect = 3.5
Identities = 21/92 (22%), Positives = 39/92 (42%), Gaps = 6/92 (6%)
Query: 177 SDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKT 236
SD ES + + DDEG+ + E + + +R+ SA + + + ++ T
Sbjct: 182 SDGESSHGDGSELDDEGMQSDDPESIRSE------RGNSRMNSAGMKSKESGENSEQANT 235
Query: 237 SDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLD 268
D H S K+ R ++ R++LD
Sbjct: 236 QDSGGSQLLEHPSRKIFRKSRISEEDDRSELD 267
>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
Length = 482
Score = 37.7 bits (86), Expect = 0.029
Identities = 43/194 (22%), Positives = 78/194 (40%), Gaps = 23/194 (11%)
Query: 51 KKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLA 110
KK E + + ++E++K Q E M D+QE L + + G V +FQ+
Sbjct: 165 KKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQS----------I 214
Query: 111 SELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRL 170
+ L + K +S +N ++ + + + ++ + K QP +N AP K
Sbjct: 215 AGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDN--------APAKGNKSP 266
Query: 171 IVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKR 230
P + E ++ + G A A + Q + P K TPSK
Sbjct: 267 SPPDGSPAATPEIRVNHEPEPAGGA-----TPGATLPKSPSQLRKGPPVPPPPKHTPSKE 321
Query: 231 MKRDKTSDLVEEYF 244
+K+++ L E+ F
Sbjct: 322 VKQEQILSLFEDTF 335
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 37.7 bits (86), Expect = 0.029
Identities = 43/194 (22%), Positives = 78/194 (40%), Gaps = 23/194 (11%)
Query: 51 KKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLA 110
KK E + + ++E++K Q E M D+QE L + + G V +FQ+
Sbjct: 165 KKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQS----------I 214
Query: 111 SELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRL 170
+ L + K +S +N ++ + + + ++ + K QP +N AP K
Sbjct: 215 AGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPSDN--------APAKGNKSP 266
Query: 171 IVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKR 230
P + E ++ + G A A + Q + P K TPSK
Sbjct: 267 SPPDGSPAATPEIRVNHEPEPAGGA-----TPGATLPKSPSQLRKGPPVPPPPKHTPSKE 321
Query: 231 MKRDKTSDLVEEYF 244
+K+++ L E+ F
Sbjct: 322 VKQEQILSLFEDTF 335
>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
Length = 497
Score = 37.7 bits (86), Expect = 0.029
Identities = 45/200 (22%), Positives = 82/200 (41%), Gaps = 20/200 (10%)
Query: 51 KKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLA 110
KK E + + ++E++K Q E M D+QE L + + G V +FQ+
Sbjct: 165 KKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQS----------I 214
Query: 111 SELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRL 170
+ L + K +S +N ++ + + + ++ + K QP+ K L + R +
Sbjct: 215 AGLEENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQPRKKSK---LFSRLRRKKNSD 271
Query: 171 IVPRSHSDSESEYSASNSEDDEGVAQEHEED------TNAVIFSQKIQAQNRVVSAPVGK 224
P + S S S + E + HE + A + Q + P K
Sbjct: 272 NAPAKGNKSPSPPDGSPAATPE-IRVNHEPEPAGGATPGATLPKSPSQLRKGPPVPPPPK 330
Query: 225 ETPSKRMKRDKTSDLVEEYF 244
TPSK +K+++ L E+ F
Sbjct: 331 HTPSKEVKQEQILSLFEDTF 350
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 37.7 bits (86), Expect = 0.029
Identities = 53/225 (23%), Positives = 89/225 (39%), Gaps = 20/225 (8%)
Query: 65 LKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKS---- 120
LK Y + LK S GG+ + ++++ E+ K +E KTP KS
Sbjct: 110 LKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHEN 169
Query: 121 -----VSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDK--SEFLSTAPRSLRKRLIVP 173
S + +PE + N SK S DK KN+ K +EFL T + +K L
Sbjct: 170 EQSKKSKSSSETNPE-SQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHT-KNNPKKDLKRS 227
Query: 174 RSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIF-------SQKIQAQNRVVSAPVGKET 226
++ +D SE + NS + + + + D ++ F SQ + K+
Sbjct: 228 KTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKD 287
Query: 227 PSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQT 271
K K+ ++ + S KV + + K K K D ++
Sbjct: 288 TKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTES 332
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 37.0 bits (84), Expect = 0.049
Identities = 53/227 (23%), Positives = 94/227 (41%), Gaps = 40/227 (17%)
Query: 53 PEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLASE 112
PE +++ ++ KD+ + GRD +E KV+ KH EK K ++E
Sbjct: 1173 PERQKDKEPRDRRKDRGAADA-GRDKKE------------KVFE----KHKEKKDKESTE 1215
Query: 113 LAKTPQKSVSFSLKNDPEITINVPQSS-KGHSASDKVQPKNNDKSEFLSTAPRSLRKRLI 171
K + S D + +P+ + K H+A DK + K+ +KS+ + R
Sbjct: 1216 KYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKER------- 1268
Query: 172 VPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVI-------FSQKIQAQNRVVSAPVGK 224
+S +++E S ++E + E+ ED+N I F+ + Q V
Sbjct: 1269 --KSSRSADAEKSLLEKLEEEAL-HEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSF 1325
Query: 225 ETPSKRMKRDKTSDLVEEYFEAH-----SSSKVLTSDRTLQKLKRAK 266
P K +++ L E+ E SSS + DR K ++A+
Sbjct: 1326 TEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAE 1372
>gi|38373673 synaptonemal complex protein 2 [Homo sapiens]
Length = 1530
Score = 36.6 bits (83), Expect = 0.065
Identities = 69/347 (19%), Positives = 138/347 (39%), Gaps = 56/347 (16%)
Query: 76 RDVQESLKNGSATG------GGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDP 129
R ++ESL N + KV RK + SE + + + +DP
Sbjct: 822 RKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDP 881
Query: 130 EITINVP--QSSKGHSASDK----VQPKNNDKSEFLSTAPRSLRKRLIVPRSH----SDS 179
I + + Q++ + +D+ V P+N+D+ L ++ ++ K++I SD+
Sbjct: 882 IIKLGIQEFQATAKEACADRSIRLVGPRNHDE---LKSSVKTKDKKIITNHQKKNLFSDT 938
Query: 180 ESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNR---------VVSAPVGKETPSKR 230
E+EY +S+ D +E + + +S+ +N P K TPSK
Sbjct: 939 ETEYRCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKN 998
Query: 231 MKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQL 290
+ + + E R +K + K + + L N S+ FS K+
Sbjct: 999 ITKKMDKTIPEGRI------------RLPRKATKTKKNYKDLSNSESECEQEFSHSFKEN 1046
Query: 291 NQQYEKLFHKWMLQLHL-GFNIVLYGLGSKRDLLERFR-TTMLQDSIH--------VVIN 340
E+ H M + L ++ ++++L ++++ +++L+D+I ++
Sbjct: 1047 IPVKEENIHSRMKTVKLPKKQQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLS 1106
Query: 341 GFFPGISVKSVLNSITEEVLDHMGTFRSILDQLDWIVNKFKEDSSLE 387
G I V + ITE+ F D + ++ + + SSLE
Sbjct: 1107 GSPSSIEVTRCIEKITEK------DFTQDYDCITKSISPYPKTSSLE 1147
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 36.2 bits (82), Expect = 0.084
Identities = 39/176 (22%), Positives = 71/176 (40%), Gaps = 13/176 (7%)
Query: 28 DREGGAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSA 87
D+E G + +KER + K+ ++ ++EE + KD RD ++ K+ +
Sbjct: 371 DKERGNEREKERERSRERSKE--QRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRS 428
Query: 88 TGGGNKVYSFQNRKH-SEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASD 146
+ RKH S ++ A + +++ K S KN+ + N S +D
Sbjct: 429 RS--------RERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTD 480
Query: 147 KVQP--KNNDKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEE 200
V+ K + RS K R HSDS+ + + + + QE +E
Sbjct: 481 SVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQE 536
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 36.2 bits (82), Expect = 0.084
Identities = 65/305 (21%), Positives = 123/305 (40%), Gaps = 61/305 (20%)
Query: 7 KEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLK 66
KE K+LE D+ ++ + E AK N K+ K E + E + + K
Sbjct: 999 KERKLLEERI---SDLTTNLAEEEEKAK----------NLTKLKNKHESMISELEVRLKK 1045
Query: 67 DQNYVEIMGRDVQESLKN---GSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSF 123
++ R E LK G A+ ++ Q ++A+L +LAK ++ +
Sbjct: 1046 EEK-----SRQELEKLKRKLEGDASDFHEQIADLQ-----AQIAELKMQLAKKEEELQAA 1095
Query: 124 SLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSESEY 183
+ D EI ++ ++A K++ S+ L++ L R+ + +
Sbjct: 1096 LARLDDEI-------AQKNNALKKIRELEGHISD--------LQEDLDSERAARNKAEKQ 1140
Query: 184 SASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNR----VVSAPVGKETPSKRMK----RDK 235
E+ E + E E+ ++ Q+++A+ V+ + +ET S + R K
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
Query: 236 TSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYE 295
+ VEE E L++ KRAK + + L K + + EL+ L Q +
Sbjct: 1201 HAQAVEELTEQ------------LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
Query: 296 KLFHK 300
++ HK
Sbjct: 1249 EVEHK 1253
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 36.2 bits (82), Expect = 0.084
Identities = 65/305 (21%), Positives = 123/305 (40%), Gaps = 61/305 (20%)
Query: 7 KEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLK 66
KE K+LE D+ ++ + E AK N K+ K E + E + + K
Sbjct: 1006 KERKLLEERI---SDLTTNLAEEEEKAK----------NLTKLKNKHESMISELEVRLKK 1052
Query: 67 DQNYVEIMGRDVQESLKN---GSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSF 123
++ R E LK G A+ ++ Q ++A+L +LAK ++ +
Sbjct: 1053 EEK-----SRQELEKLKRKLEGDASDFHEQIADLQ-----AQIAELKMQLAKKEEELQAA 1102
Query: 124 SLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSESEY 183
+ D EI ++ ++A K++ S+ L++ L R+ + +
Sbjct: 1103 LARLDDEI-------AQKNNALKKIRELEGHISD--------LQEDLDSERAARNKAEKQ 1147
Query: 184 SASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNR----VVSAPVGKETPSKRMK----RDK 235
E+ E + E E+ ++ Q+++A+ V+ + +ET S + R K
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1207
Query: 236 TSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYE 295
+ VEE E L++ KRAK + + L K + + EL+ L Q +
Sbjct: 1208 HAQAVEELTEQ------------LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255
Query: 296 KLFHK 300
++ HK
Sbjct: 1256 EVEHK 1260
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 36.2 bits (82), Expect = 0.084
Identities = 65/305 (21%), Positives = 123/305 (40%), Gaps = 61/305 (20%)
Query: 7 KEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLK 66
KE K+LE D+ ++ + E AK N K+ K E + E + + K
Sbjct: 1006 KERKLLEERI---SDLTTNLAEEEEKAK----------NLTKLKNKHESMISELEVRLKK 1052
Query: 67 DQNYVEIMGRDVQESLKN---GSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSF 123
++ R E LK G A+ ++ Q ++A+L +LAK ++ +
Sbjct: 1053 EEK-----SRQELEKLKRKLEGDASDFHEQIADLQ-----AQIAELKMQLAKKEEELQAA 1102
Query: 124 SLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSESEY 183
+ D EI ++ ++A K++ S+ L++ L R+ + +
Sbjct: 1103 LARLDDEI-------AQKNNALKKIRELEGHISD--------LQEDLDSERAARNKAEKQ 1147
Query: 184 SASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNR----VVSAPVGKETPSKRMK----RDK 235
E+ E + E E+ ++ Q+++A+ V+ + +ET S + R K
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1207
Query: 236 TSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYE 295
+ VEE E L++ KRAK + + L K + + EL+ L Q +
Sbjct: 1208 HAQAVEELTEQ------------LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255
Query: 296 KLFHK 300
++ HK
Sbjct: 1256 EVEHK 1260
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 36.2 bits (82), Expect = 0.084
Identities = 65/305 (21%), Positives = 123/305 (40%), Gaps = 61/305 (20%)
Query: 7 KEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLK 66
KE K+LE D+ ++ + E AK N K+ K E + E + + K
Sbjct: 999 KERKLLEERI---SDLTTNLAEEEEKAK----------NLTKLKNKHESMISELEVRLKK 1045
Query: 67 DQNYVEIMGRDVQESLKN---GSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSF 123
++ R E LK G A+ ++ Q ++A+L +LAK ++ +
Sbjct: 1046 EEK-----SRQELEKLKRKLEGDASDFHEQIADLQ-----AQIAELKMQLAKKEEELQAA 1095
Query: 124 SLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSESEY 183
+ D EI ++ ++A K++ S+ L++ L R+ + +
Sbjct: 1096 LARLDDEI-------AQKNNALKKIRELEGHISD--------LQEDLDSERAARNKAEKQ 1140
Query: 184 SASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNR----VVSAPVGKETPSKRMK----RDK 235
E+ E + E E+ ++ Q+++A+ V+ + +ET S + R K
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQK 1200
Query: 236 TSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYE 295
+ VEE E L++ KRAK + + L K + + EL+ L Q +
Sbjct: 1201 HAQAVEELTEQ------------LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
Query: 296 KLFHK 300
++ HK
Sbjct: 1249 EVEHK 1253
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 36.2 bits (82), Expect = 0.084
Identities = 39/183 (21%), Positives = 73/183 (39%), Gaps = 18/183 (9%)
Query: 92 NKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPK 151
N+ + + KH EK+ + +K Q+ K+ SS S+SD
Sbjct: 56 NENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGR-------YSSSSSSSSDSSSSS 108
Query: 152 NNDKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQ--------EHEEDTN 203
++ + E R +K+ RSH SES S + S+ + + + E E+D
Sbjct: 109 SDSEDEDKKQGKRRKKKK---NRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIK 165
Query: 204 AVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLK 263
+ +K+ ++++ +S+ E+ R K EE +A +K + K K
Sbjct: 166 GLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKK 225
Query: 264 RAK 266
+ K
Sbjct: 226 KKK 228
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 36.2 bits (82), Expect = 0.084
Identities = 39/183 (21%), Positives = 73/183 (39%), Gaps = 18/183 (9%)
Query: 92 NKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPK 151
N+ + + KH EK+ + +K Q+ K+ SS S+SD
Sbjct: 66 NENWKKELEKHREKLLSGSESSSKKRQRKKKEKKKSGR-------YSSSSSSSSDSSSSS 118
Query: 152 NNDKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQ--------EHEEDTN 203
++ + E R +K+ RSH SES S + S+ + + + E E+D
Sbjct: 119 SDSEDEDKKQGKRRKKKK---NRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIK 175
Query: 204 AVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLK 263
+ +K+ ++++ +S+ E+ R K EE +A +K + K K
Sbjct: 176 GLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKKKKKHKKHSKKK 235
Query: 264 RAK 266
+ K
Sbjct: 236 KKK 238
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 35.8 bits (81), Expect = 0.11
Identities = 58/278 (20%), Positives = 109/278 (39%), Gaps = 31/278 (11%)
Query: 19 DDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEEDD------------QEVLK 66
DD L+ + GA KE+ KK +K + D +EDD Q +
Sbjct: 15 DDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKA 74
Query: 67 DQNYVEIMGRDVQE---SLKNGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSF 123
D+ V + + E + K+ G K SF + SE++ S+ KT + V
Sbjct: 75 DRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDD-NDSEELEDKDSKSKKTAKPKVEM 133
Query: 124 SLKNDPEITIN-VPQSSKGHSASDKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSESE 182
+D + N +P+ +KG + + +++ E S + R R+ D E
Sbjct: 134 YSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKE-RSRINSSGESGDESDE 192
Query: 183 YSAS------NSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKRDKT 236
+ S N ++ G E + + F K AQ + ++ +R KRD+
Sbjct: 193 FLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKK------AEKKERERKKRDEE 246
Query: 237 SDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRN 274
+ + E + D++ QK + K +++T+++
Sbjct: 247 KAKLRKLKE-KEELETGKKDQSKQKESQRKFEEETVKS 283
>gi|37675268 zinc finger protein 200 isoform 2 [Homo sapiens]
Length = 394
Score = 35.0 bits (79), Expect = 0.19
Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 26/159 (16%)
Query: 96 SFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITI----NVPQSSKGHSASDKVQPK 151
S QNR H + KL + + Q++VS LK +PE+ + NV + + D Q
Sbjct: 79 SLQNRVHPRPLVKLLPKGVQKEQETVSLYLKANPELVVFEDLNVFHCQEECVSLDPTQQL 138
Query: 152 NNDKSEFLSTAPRSLRKRLIVPRSHSDSE---------SEYSASNSEDDEG----VAQE- 197
++K + S L L V S+ + E +Y +S+DDE V+Q+
Sbjct: 139 TSEKEDDSSVGEMML---LAVNGSNPEGEDPEREPVENEDYREKSSDDDEMDSSLVSQQP 195
Query: 198 ---HEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKR 233
E++ QK + +N +V+ + +TP + + +
Sbjct: 196 PDNQEKERLNTSIPQKRKMRNLLVT--IENDTPLEELSK 232
>gi|14165274 golgi-associated microtubule-binding protein HOOK3
[Homo sapiens]
Length = 718
Score = 35.0 bits (79), Expect = 0.19
Identities = 64/324 (19%), Positives = 128/324 (39%), Gaps = 61/324 (18%)
Query: 21 DVLNHILDR----EGGAKLKKERAQLLVNPKKIIKKPE----------YDLEEDDQEVLK 66
DVL H D+ EG + K++ + L + ++ +K E LEE+ ++
Sbjct: 304 DVLRHSSDKVSKLEGQVESYKKKLEDLGDLRRQVKLLEEKNTMYMQNTVSLEEELRKANA 363
Query: 67 DQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLK 126
++ +E R V E S F+ ++ EK+ L E K ++ SLK
Sbjct: 364 ARSQLETYKRQVVELQNRLSEESKKADKLDFEYKRLKEKVDSLQKE--KDRLRTERDSLK 421
Query: 127 NDPEITINVPQSSKGHSASDKVQPKNNDKSEFLSTAP---RSLRKRLI----------VP 173
E + Q+ +G + + P + +S A +R++LI +
Sbjct: 422 ETIE-ELRCVQAQEGQLTTQGLMPLGSQESSDSLAAEIVTPEIREKLIRLQHENKMLKLN 480
Query: 174 RSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKRMKR 233
+ SD+E + DD + + E N ++ + ++ Q++V +++ + +
Sbjct: 481 QEGSDNEKIALLQSLLDDANLRKNELETENRLVNQRLLEVQSQVEEL---QKSLQDQGSK 537
Query: 234 DKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLRNLLSKVSPSFS--------- 284
+ S L+++ E H L+KL A + Q R ++ + P F+
Sbjct: 538 AEDSVLLKKKLEEH-----------LEKLHEANNELQKKRAIIEDLEPRFNNSSLKIEEL 586
Query: 285 --------AELKQLNQQYEKLFHK 300
E+KQ+ ++Y+K K
Sbjct: 587 QEALRKKEEEMKQMEERYKKYLEK 610
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 35.0 bits (79), Expect = 0.19
Identities = 44/221 (19%), Positives = 94/221 (42%), Gaps = 33/221 (14%)
Query: 104 EKMAKLASELAKTPQKSVS---FSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSEFLS 160
+++A LA E ++ +K L+NDP++ Q + H D+++ K ++ FL
Sbjct: 1036 QRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQ 1095
Query: 161 TAPRSLRKRLI----------VPRSHSDSESEYSASN----SEDDEGVAQEHEEDTNAVI 206
+ L K V + D+ +E S+ ED+ A+ + + ++
Sbjct: 1096 DKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREKTELL 1155
Query: 207 FSQKIQAQNRVVSAPVGKETPSKRMKRDKTS---------DLVEEYFEAHSSSKVLTSDR 257
+KI A + V +E + ++ D + +LVE+ + + + L S +
Sbjct: 1156 --RKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQ 1213
Query: 258 T-LQKLKR----AKLDQQTLRNLLSKVSPSFSAELKQLNQQ 293
+ L+ L+R ++ + T + K P EL++L ++
Sbjct: 1214 SELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREE 1254
>gi|54633319 PDZ domain-containing guanine nucleotide exchange factor
I [Homo sapiens]
Length = 1601
Score = 34.7 bits (78), Expect = 0.25
Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 9/103 (8%)
Query: 24 NHILDREGGAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLK 83
+++LD +GGA K+ R L+N KK L ED Q K + Y+ + + E K
Sbjct: 1076 SNMLDVQGGAHKKRARRSSLLNAKK--------LYEDAQMARKVKQYLSSLDVETDEE-K 1126
Query: 84 NGSATGGGNKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLK 126
+ Y + SEK + +SE++ P +S + K
Sbjct: 1127 FQMMSLQWEPAYGTLTKNLSEKRSAKSSEMSPVPMRSAGQTTK 1169
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 34.7 bits (78), Expect = 0.25
Identities = 65/323 (20%), Positives = 122/323 (37%), Gaps = 65/323 (20%)
Query: 5 ELKEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEY--------- 55
E KE K+ E+ + ++++ I KLK+ER+ L +K++++ E+
Sbjct: 186 EKKEAKLKEIKTILEEEITPTI------QKLKEERSSYL-EYQKVMREIEHLSRLYIAYQ 238
Query: 56 -----DLEEDDQEVLKD-QNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKL 109
D + E LK+ Q+ V + ++ E+ K A +++ + RK E L
Sbjct: 239 FLLAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKALN--HEIEELEKRKDKETGGIL 296
Query: 110 AS------ELAKTPQKSVS-FSLKND---------PEITINVPQSSKGHSASDKVQPKNN 153
S E + KS S F LK E+ N+ + SK +A +K K
Sbjct: 297 RSLEDALAEAQRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKIT 356
Query: 154 DKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQA 213
D L A + L + H ++ S +SN E+ A + Q +
Sbjct: 357 DGLHALQEASNKDAEALAAAQQHFNAVSAGLSSN-----------EDGAEATLAGQMMAC 405
Query: 214 QNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLR 273
+N + A + ++K H+ ++ ++K+ Q
Sbjct: 406 KNDISKAQTEAKQAQMKLK--------------HAQQELKNKQAEVKKMDSGYRKDQEAL 451
Query: 274 NLLSKVSPSFSAELKQLNQQYEK 296
+ ++ AE+K+LN + K
Sbjct: 452 EAVKRLKEKLEAEMKKLNYEENK 474
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 34.7 bits (78), Expect = 0.25
Identities = 65/323 (20%), Positives = 122/323 (37%), Gaps = 65/323 (20%)
Query: 5 ELKEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEY--------- 55
E KE K+ E+ + ++++ I KLK+ER+ L +K++++ E+
Sbjct: 186 EKKEAKLKEIKTILEEEITPTI------QKLKEERSSYL-EYQKVMREIEHLSRLYIAYQ 238
Query: 56 -----DLEEDDQEVLKD-QNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKL 109
D + E LK+ Q+ V + ++ E+ K A +++ + RK E L
Sbjct: 239 FLLAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKALN--HEIEELEKRKDKETGGIL 296
Query: 110 AS------ELAKTPQKSVS-FSLKND---------PEITINVPQSSKGHSASDKVQPKNN 153
S E + KS S F LK E+ N+ + SK +A +K K
Sbjct: 297 RSLEDALAEAQRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKIT 356
Query: 154 DKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQA 213
D L A + L + H ++ S +SN E+ A + Q +
Sbjct: 357 DGLHALQEASNKDAEALAAAQQHFNAVSAGLSSN-----------EDGAEATLAGQMMAC 405
Query: 214 QNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLR 273
+N + A + ++K H+ ++ ++K+ Q
Sbjct: 406 KNDISKAQTEAKQAQMKLK--------------HAQQELKNKQAEVKKMDSGYRKDQEAL 451
Query: 274 NLLSKVSPSFSAELKQLNQQYEK 296
+ ++ AE+K+LN + K
Sbjct: 452 EAVKRLKEKLEAEMKKLNYEENK 474
>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 34.7 bits (78), Expect = 0.25
Identities = 65/323 (20%), Positives = 122/323 (37%), Gaps = 65/323 (20%)
Query: 5 ELKEDKMLEVHFVGDDDVLNHILDREGGAKLKKERAQLLVNPKKIIKKPEY--------- 55
E KE K+ E+ + ++++ I KLK+ER+ L +K++++ E+
Sbjct: 186 EKKEAKLKEIKTILEEEITPTI------QKLKEERSSYL-EYQKVMREIEHLSRLYIAYQ 238
Query: 56 -----DLEEDDQEVLKD-QNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEKMAKL 109
D + E LK+ Q+ V + ++ E+ K A +++ + RK E L
Sbjct: 239 FLLAEDTKVRSAEELKEMQDKVIKLQEELSENDKKIKALN--HEIEELEKRKDKETGGIL 296
Query: 110 AS------ELAKTPQKSVS-FSLKND---------PEITINVPQSSKGHSASDKVQPKNN 153
S E + KS S F LK E+ N+ + SK +A +K K
Sbjct: 297 RSLEDALAEAQRVNTKSQSAFDLKKKNLACEESKRKELEKNMVEDSKTLAAKEKEVKKIT 356
Query: 154 DKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQA 213
D L A + L + H ++ S +SN E+ A + Q +
Sbjct: 357 DGLHALQEASNKDAEALAAAQQHFNAVSAGLSSN-----------EDGAEATLAGQMMAC 405
Query: 214 QNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLR 273
+N + A + ++K H+ ++ ++K+ Q
Sbjct: 406 KNDISKAQTEAKQAQMKLK--------------HAQQELKNKQAEVKKMDSGYRKDQEAL 451
Query: 274 NLLSKVSPSFSAELKQLNQQYEK 296
+ ++ AE+K+LN + K
Sbjct: 452 EAVKRLKEKLEAEMKKLNYEENK 474
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 34.7 bits (78), Expect = 0.25
Identities = 53/227 (23%), Positives = 102/227 (44%), Gaps = 38/227 (16%)
Query: 104 EKMAKLASELAKTPQKSVSFSLKNDPEITINVP---------QSSKGHSASDKVQPKNND 154
E++A+LA +L + QK + + K + +T + Q+S+ H+ + + K
Sbjct: 2703 ERVAELARDLVEMEQKLLMVT-KENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKY 2761
Query: 155 KSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQ-- 212
+ A + L R SE+ +S +++E++ + H E N + S+ Q
Sbjct: 2762 DASLKELAQLKEQGLLNRERDALLSETAFSMNSTEEN---SLSHLEKLNQQLLSKDEQLL 2818
Query: 213 --------AQNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAH-----SSSKVLTSDRTL 259
+ N+V S K S + +RD + +E++ ++ S+++ TS +
Sbjct: 2819 HLSSQLEDSYNQVQS--FSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEV 2876
Query: 260 QKLKRAKLDQQTLRNLLSKVSPSFSAELKQLNQQYEKLFHKWMLQLH 306
Q LK+A Q R+ L K ELK L QQY ++ ++ + +LH
Sbjct: 2877 QSLKKAMSSLQNDRDRLLK-------ELKNLQQQYLQI-NQEITELH 2915
Score = 33.9 bits (76), Expect = 0.42
Identities = 42/187 (22%), Positives = 80/187 (42%), Gaps = 10/187 (5%)
Query: 98 QNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNNDKSE 157
Q ++H E++ +L EL + QK ++ + I + S + ++ +N E
Sbjct: 1446 QAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALK-ENKSLQE 1504
Query: 158 FLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQ----EHEEDTNAVIFSQKIQA 213
LS A ++ + + +S +D ES+ SA N E D + + + E D + +
Sbjct: 1505 ELSLARGTIER---LTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLE 1561
Query: 214 QNRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQTLR 273
+ S+ + + + DK LV+E E+ SSK+ S +K K + + + L
Sbjct: 1562 NQSLSSSCESLKLALEGLTEDK-EKLVKE-IESLKSSKIAESTEWQEKHKELQKEYEILL 1619
Query: 274 NLLSKVS 280
VS
Sbjct: 1620 QSYENVS 1626
Score = 30.4 bits (67), Expect = 4.6
Identities = 59/268 (22%), Positives = 106/268 (39%), Gaps = 37/268 (13%)
Query: 33 AKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGN 92
A++K E LL + K +KK +LEE+ Q+++K++ VE R G+ GN
Sbjct: 1947 AQIKNE---LLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGN 2003
Query: 93 KVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKN 152
K + AK EL K Q+ V K+ + + A + VQ ++
Sbjct: 2004 KSH-----------AKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTES 2052
Query: 153 NDKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQ 212
E ++ L H AS V + + A + + ++
Sbjct: 2053 QKDLEI-------TKENLAQAVEHRKKAQAELASFK-----VLLDDTQSEAARVLADNLK 2100
Query: 213 AQNRVVSAPVGKETPSKRMKRDKTSDL---VEEYFEAHSSSKVLTSDRTLQKLKRAKLDQ 269
+ + S KE+ +MK+ K DL +E+ E H K ++ L L+R K+
Sbjct: 2101 LKKELQS---NKESVKSQMKQ-KDEDLERRLEQAEEKHLKEKKNMQEK-LDALRREKVH- 2154
Query: 270 QTLRNLLSKVSPSFSAELKQLNQQYEKL 297
L + ++ + + + K++ Q E L
Sbjct: 2155 --LEETIGEIQVTLNKKDKEVQQLQENL 2180
Score = 30.0 bits (66), Expect = 6.1
Identities = 46/223 (20%), Positives = 90/223 (40%), Gaps = 24/223 (10%)
Query: 92 NKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPK 151
N V +N+K +K +L L KT +K N+ Q ++ S +
Sbjct: 2424 NIVLEEENKKAVDKTNQLMETL-KTIKKE-------------NIQQKAQLDSFVKSMSSL 2469
Query: 152 NNDKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVA--QEHEEDTN---AVI 206
ND+ + + + L + E +A N++ E + + H +D N A +
Sbjct: 2470 QNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKL 2529
Query: 207 FSQKIQAQ---NRVVSAPVGKETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLK 263
++ IQ + N+V++ ++ ++ + +L +Y A K+ S+ + L+
Sbjct: 2530 DAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKY--AKLEEKLKESEEANEDLR 2587
Query: 264 RAKLDQQTLRNLLSKVSPSFSAELKQLNQQYEKLFHKWMLQLH 306
R+ Q + LSK S + QL +Q L + L L+
Sbjct: 2588 RSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLY 2630
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 34.7 bits (78), Expect = 0.25
Identities = 24/97 (24%), Positives = 42/97 (43%), Gaps = 12/97 (12%)
Query: 146 DKVQPKNNDKSEFLSTAPRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAV 205
+ ++P K L + P +HSD E E + ED+E + + ++DT V
Sbjct: 463 ENIKPSLGSKKNLLESIP-----------THSDQEKEVNIKKPEDNENL-DDKDDDTTRV 510
Query: 206 IFSQKIQAQNRVVSAPVGKETPSKRMKRDKTSDLVEE 242
S I+ + A G ET + + D+ ++ EE
Sbjct: 511 DESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEE 547
Score = 29.6 bits (65), Expect = 7.9
Identities = 28/160 (17%), Positives = 65/160 (40%), Gaps = 23/160 (14%)
Query: 46 PKKIIKKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGGNKVYSFQNRKHSEK 105
P+K++ K + E + +K++N EI ++E + + + ++
Sbjct: 409 PEKVVNKQCKECENVKEIKVKEENETEIKEIKMEEE----------RNIIPREEKPIEDE 458
Query: 106 MAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPKNN----DKSEFLST 161
+ + ++++ SL + + ++P S + +P++N DK + +
Sbjct: 459 IER---------KENIKPSLGSKKNLLESIPTHSDQEKEVNIKKPEDNENLDDKDDDTTR 509
Query: 162 APRSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEED 201
SL ++ + S E + EDDE +E EE+
Sbjct: 510 VDESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEE 549
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 33.9 bits (76), Expect = 0.42
Identities = 51/270 (18%), Positives = 108/270 (40%), Gaps = 26/270 (9%)
Query: 32 GAKLKKERAQLLVNPKKIIKKPEYDLEEDDQEVLKDQNYVEIMGRDVQESLKNGSATGGG 91
G++L+K+ +L I++ E +LE + K + + R+++E + GG
Sbjct: 1101 GSQLQKKLKELQAR----IEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA 1156
Query: 92 NKVYSFQNRKHSEKMAKLASELAKTPQKSVSFSLKNDPEITINVPQSSKGHSASDKVQPK 151
V N+K + K+ +L + + + + + +V + + +V+ K
Sbjct: 1157 TSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQK 1216
Query: 152 -NNDKSEFLSTAP--RSLRKRLIVPRSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFS 208
+KSEF S +++I +++ + + A+E + N +
Sbjct: 1217 LEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQ 1276
Query: 209 Q-KIQAQNRVVSAPVG-KETPSKRMKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAK 266
+ K+Q +N +S + KE ++ R K LT + L+ LKR
Sbjct: 1277 RAKLQTENGELSRQLDEKEALISQLTRGK-----------------LTYTQQLEDLKRQL 1319
Query: 267 LDQQTLRNLLSKVSPSFSAELKQLNQQYEK 296
++ +N L+ S + L +QYE+
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEE 1349
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 33.9 bits (76), Expect = 0.42
Identities = 63/292 (21%), Positives = 111/292 (38%), Gaps = 54/292 (18%)
Query: 35 LKKERAQLLVNPKKIIKKPEYDLEEDDQEVL----------------KDQNYV--EIMGR 76
L K + Q+L + KKI+KK + D+ D+ + KD N + +
Sbjct: 244 LTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPE 303
Query: 77 DVQESLKNGSATGGGNKVYSFQNRKHSEKMAKL-ASELAKTP------QKSVSFSLKNDP 129
V E L GS+ GN++ + Q K L S + P Q+ +L+ +
Sbjct: 304 KVSEPLP-GSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQ 362
Query: 130 EITINVPQSSKGHSASDKVQPK-----NNDKSEFL-----------STAPRSLRKRLIVP 173
+ + + + H S+K QP+ N +KSE + S A L ++ +
Sbjct: 363 ALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIG 422
Query: 174 RSHSDSESEYSASNSEDDEGVAQEHEEDTNAVIFSQKIQAQNRVVSAPVGKETPSKR--- 230
+++ + D + QE+EE TN + +K + + KE +K+
Sbjct: 423 KTY-PQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEP 481
Query: 231 ------MKRDKTSDLVEEYFEAHSSSKVLTSDRTLQKLKRAKLDQQ--TLRN 274
MK + F H K L + + K A L Q+ T++N
Sbjct: 482 TVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCILKADIAILRQEICTMKN 533
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,524,795
Number of Sequences: 37866
Number of extensions: 895685
Number of successful extensions: 2930
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 123
Number of HSP's that attempted gapping in prelim test: 2837
Number of HSP's gapped (non-prelim): 233
length of query: 577
length of database: 18,247,518
effective HSP length: 108
effective length of query: 469
effective length of database: 14,157,990
effective search space: 6640097310
effective search space used: 6640097310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.