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Search of human proteins with 5453734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453734 MAD4 [Homo sapiens]
(209 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453734 MAD4 [Homo sapiens] 411 e-115
gi|57242782 MAX interactor 1 isoform a [Homo sapiens] 184 6e-47
gi|4505069 MAX dimerization protein 1 [Homo sapiens] 184 6e-47
gi|47717116 MAX interactor 1 isoform b [Homo sapiens] 175 2e-44
gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens] 147 6e-36
gi|57242784 MAX interactor 1 isoform c [Homo sapiens] 139 1e-33
gi|219283190 MAX dimerization protein 3 isoform b [Homo sapiens] 139 2e-33
gi|64762402 transcription factor EC isoform b [Homo sapiens] 46 2e-05
gi|6912702 transcription factor EC isoform a [Homo sapiens] 46 2e-05
gi|9945318 MAX binding protein [Homo sapiens] 46 3e-05
gi|71774083 myc proto-oncogene protein [Homo sapiens] 45 6e-05
gi|8659574 transcription factor E3 [Homo sapiens] 44 8e-05
gi|38156705 microphthalmia-associated transcription factor isofo... 43 2e-04
gi|38156703 microphthalmia-associated transcription factor isofo... 43 2e-04
gi|38156701 microphthalmia-associated transcription factor isofo... 43 2e-04
gi|38156699 microphthalmia-associated transcription factor isofo... 43 2e-04
gi|38156697 microphthalmia-associated transcription factor isofo... 43 2e-04
gi|4557755 microphthalmia-associated transcription factor isofor... 42 5e-04
gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens] 42 5e-04
gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens] 42 5e-04
gi|8922477 polymerase (RNA) III (DNA directed) polypeptide E [Ho... 42 5e-04
gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro... 40 0.001
gi|24307933 transcription factor EB [Homo sapiens] 40 0.001
gi|114431248 hypothetical protein LOC205717 [Homo sapiens] 40 0.001
gi|27477113 sterol regulatory element-binding transcription fact... 40 0.001
gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens] 40 0.001
gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens] 40 0.001
gi|239047343 spermatogenesis and oogenesis specific basic helix-... 39 0.003
gi|7705415 hook homolog 1 [Homo sapiens] 38 0.007
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ... 37 0.009
>gi|5453734 MAD4 [Homo sapiens]
Length = 209
Score = 411 bits (1056), Expect = e-115
Identities = 209/209 (100%), Positives = 209/209 (100%)
Query: 1 MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNE 60
MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNE
Sbjct: 1 MELNSLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNE 60
Query: 61 LEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQ 120
LEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQ
Sbjct: 61 LEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQ 120
Query: 121 QEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDA 180
QEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDA
Sbjct: 121 QEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVGSSSDA 180
Query: 181 DDHYSLQSGTGGDSGFGPHCRRLGRPALS 209
DDHYSLQSGTGGDSGFGPHCRRLGRPALS
Sbjct: 181 DDHYSLQSGTGGDSGFGPHCRRLGRPALS 209
>gi|57242782 MAX interactor 1 isoform a [Homo sapiens]
Length = 228
Score = 184 bits (466), Expect = 6e-47
Identities = 110/207 (53%), Positives = 137/207 (66%), Gaps = 20/207 (9%)
Query: 9 LLEAAEYLERRDREAEHGYASVLPFDGD-----------FAREKTKAAGLVRKAPNNRSS 57
LLEAAE+LERR+RE EHGYAS P +R + ++G + NRS+
Sbjct: 12 LLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRST 71
Query: 58 HNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKE 117
HNELEK+RRA LRL LE+LK L+PLGPD TRHTTL LL +AK HIKKLEE +R++ E
Sbjct: 72 HNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLE 131
Query: 118 QLQQEHRFLKRRLEQL-SVQSVERVRTDSTGSAVSTD--DSEQ---EVDIEGMEFGPGEL 171
L++E RFLK RLEQL Q +ER+R DS GS +S+D DSE+ EVD+E EF GE+
Sbjct: 132 NLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEV 191
Query: 172 DSVG--SSSDADDHYSLQSGTGGDSGF 196
D++ S SD DDH SL S G D G+
Sbjct: 192 DNISTTSISDIDDHSSLPS-IGSDEGY 217
>gi|4505069 MAX dimerization protein 1 [Homo sapiens]
Length = 221
Score = 184 bits (466), Expect = 6e-47
Identities = 107/201 (53%), Positives = 149/201 (74%), Gaps = 16/201 (7%)
Query: 5 SLLILLEAAEYLERRDREAEHGYASVLPF---DGDFAREKTKAAGLVRKAPNNRSSHNEL 61
++ +LLEAA+YLERR+REAEHGYAS+LP+ D D + + K+ + ++RS+HNE+
Sbjct: 8 NIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSK---KNNSSSRSTHNEM 64
Query: 62 EKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQ 121
EK+RRA LRL LE+LK LVPLGP+S+RHTTLSLL +AK+HIKKLE+ DR+A+ +QLQ+
Sbjct: 65 EKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQR 124
Query: 122 EHRFLKRRLEQLSVQSVERVRTDSTGSAVSTD--DSEQE---VDIEGMEFGPGELD-SVG 175
E R LKR+LE+L +ER+R DS GS VS++ DS++E VD+E ++ G+LD S
Sbjct: 125 EQRHLKRQLEKL---GIERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLDWSSS 181
Query: 176 SSSDADDHYSLQSGTGGDSGF 196
S SD+D+ S+QS G D G+
Sbjct: 182 SVSDSDERGSMQS-LGSDEGY 201
>gi|47717116 MAX interactor 1 isoform b [Homo sapiens]
Length = 295
Score = 175 bits (444), Expect = 2e-44
Identities = 109/216 (50%), Positives = 139/216 (64%), Gaps = 23/216 (10%)
Query: 3 LNSLLILLEAAEYLERRDRE---AEHGYASVLPFDGD-----------FAREKTKAAGLV 48
L ++ ILLEAA YLE+ ++E EHGYAS P +R + ++G
Sbjct: 70 LQNVQILLEAASYLEQIEKENKKCEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSSGSS 129
Query: 49 RKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQ 108
+ NRS+HNELEK+RRA LRL LE+LK L+PLGPD TRHTTL LL +AK HIKKLEE
Sbjct: 130 NTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEA 189
Query: 109 DRRALSIKEQLQQEHRFLKRRLEQL-SVQSVERVRTDSTGSAVSTD--DSEQ---EVDIE 162
+R++ E L++E RFLK RLEQL Q +ER+R DS GS +S+D DSE+ EVD+E
Sbjct: 190 ERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVE 249
Query: 163 GMEFGPGELDSVG--SSSDADDHYSLQSGTGGDSGF 196
EF GE+D++ S SD DDH SL S G D G+
Sbjct: 250 STEFSHGEVDNISTTSISDIDDHSSLPS-IGSDEGY 284
>gi|13775222 MAX dimerization protein 3 isoform a [Homo sapiens]
Length = 206
Score = 147 bits (371), Expect = 6e-36
Identities = 86/192 (44%), Positives = 123/192 (64%), Gaps = 13/192 (6%)
Query: 4 NSLLILLEAAEYLERRDREAEHGYASVLPF--DGDFAREKTKAAGLVRKAPNNRSSHNEL 61
+++ +LL+AAE+LERR+REAEHGYAS+ P G R K + + RS HNEL
Sbjct: 6 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 65
Query: 62 EKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQ 121
EK RRA+L+ LE+LKQ +PLG D R+TTLSLL+RA++HI+KLE+Q++RA +KE+L+
Sbjct: 66 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 125
Query: 122 EHRFLKRRLEQL----SVQSVERVRTDSTGSA------VSTDDSEQEVDIEGMEFGPGEL 171
+ + L+R+LEQL ER+R DS S+ +D E EVD+E + FG GE
Sbjct: 126 KQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFG-GEA 184
Query: 172 DSVGSSSDADDH 183
+ + +H
Sbjct: 185 ELLRGFVAGQEH 196
>gi|57242784 MAX interactor 1 isoform c [Homo sapiens]
Length = 182
Score = 139 bits (351), Expect = 1e-33
Identities = 84/158 (53%), Positives = 105/158 (66%), Gaps = 9/158 (5%)
Query: 47 LVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLE 106
L R ++ S N +RRA LRL LE+LK L+PLGPD TRHTTL LL +AK HIKKLE
Sbjct: 15 LSRAQKHSSGSSNTSTANRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLE 74
Query: 107 EQDRRALSIKEQLQQEHRFLKRRLEQL-SVQSVERVRTDSTGSAVSTD--DSEQ---EVD 160
E +R++ E L++E RFLK RLEQL Q +ER+R DS GS +S+D DSE+ EVD
Sbjct: 75 EAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVD 134
Query: 161 IEGMEFGPGELDSVG--SSSDADDHYSLQSGTGGDSGF 196
+E EF GE+D++ S SD DDH SL S G D G+
Sbjct: 135 VESTEFSHGEVDNISTTSISDIDDHSSLPS-IGSDEGY 171
>gi|219283190 MAX dimerization protein 3 isoform b [Homo sapiens]
Length = 193
Score = 139 bits (350), Expect = 2e-33
Identities = 80/188 (42%), Positives = 119/188 (63%), Gaps = 7/188 (3%)
Query: 4 NSLLILLEAAEYLERRDREAEHGYASVLPF--DGDFAREKTKAAGLVRKAPNNRSSHNEL 61
+++ +LL+AAE+LERR+REAEHGYAS+ P G R K + + RS HNEL
Sbjct: 6 SNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNEL 65
Query: 62 EKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQ 121
EK RRA+L+ LE+LKQ +PLG D R+TTLSLL+RA++HI+KLE+Q++RA +KE+L+
Sbjct: 66 EKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRS 125
Query: 122 EHRFLKRRLEQL----SVQSVERVRTDS-TGSAVSTDDSEQEVDIEGMEFGPGELDSVGS 176
+ + L+R+LEQL ER+R DS S +S++ S+ + + G G
Sbjct: 126 KQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQVLPNENGGTPNHRPTGR 185
Query: 177 SSDADDHY 184
++ H+
Sbjct: 186 GNNISSHH 193
>gi|64762402 transcription factor EC isoform b [Homo sapiens]
Length = 318
Score = 46.2 bits (108), Expect = 2e-05
Identities = 31/113 (27%), Positives = 61/113 (53%), Gaps = 7/113 (6%)
Query: 29 SVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-ST 87
S LP + T+A R+ +N HN +E+ RR + +++L L+P D
Sbjct: 89 SSLPMKREITETDTRALAKERQKKDN---HNLIERRRRYNINYRIKELGTLIPKSNDPDM 145
Query: 88 RHTTLSLLKRAKVHIKKLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137
R ++LK + +IK L+++ +RA + +++L+Q +R L R+++L +Q+
Sbjct: 146 RWNKGTILKASVEYIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELEIQA 198
>gi|6912702 transcription factor EC isoform a [Homo sapiens]
Length = 347
Score = 46.2 bits (108), Expect = 2e-05
Identities = 31/113 (27%), Positives = 61/113 (53%), Gaps = 7/113 (6%)
Query: 29 SVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-ST 87
S LP + T+A R+ +N HN +E+ RR + +++L L+P D
Sbjct: 118 SSLPMKREITETDTRALAKERQKKDN---HNLIERRRRYNINYRIKELGTLIPKSNDPDM 174
Query: 88 RHTTLSLLKRAKVHIKKLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137
R ++LK + +IK L+++ +RA + +++L+Q +R L R+++L +Q+
Sbjct: 175 RWNKGTILKASVEYIKWLQKEQQRARELEHRQKKLEQANRRLLLRIQELEIQA 227
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 45.8 bits (107), Expect = 3e-05
Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 16/125 (12%)
Query: 55 RSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALS 114
R HN+LEK+RRA L+ E LK+ +P D + + LS+L+ A +I+ L+ +++
Sbjct: 222 REVHNKLEKNRRAHLKECFETLKRNIP-NVDDKKTSNLSVLRTALRYIQSLKRKEKEYEH 280
Query: 115 IKEQLQQEHRFLKRRLEQL--------SVQSVERV------RTDSTGSAVSTDDSEQEVD 160
E+L +E ++RL +L V ++RV D S + + E +D
Sbjct: 281 EMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNID 340
Query: 161 IEGME 165
E ME
Sbjct: 341 -EDME 344
>gi|71774083 myc proto-oncogene protein [Homo sapiens]
Length = 454
Score = 44.7 bits (104), Expect = 6e-05
Identities = 31/129 (24%), Positives = 63/129 (48%), Gaps = 19/129 (14%)
Query: 24 EHGYASVLPFDGDFA---REKTKAAGLVRKAPNNRS----------------SHNELEKH 64
+H YA+ D+ R K + ++R+ NNR +HN LE+
Sbjct: 321 QHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENVKRRTHNVLERQ 380
Query: 65 RRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHR 124
RR +L+ L+ +P ++ + + +LK+A +I ++ ++++ +S ++ L++
Sbjct: 381 RRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQAEEQKLISEEDLLRKRRE 440
Query: 125 FLKRRLEQL 133
LK +LEQL
Sbjct: 441 QLKHKLEQL 449
>gi|8659574 transcription factor E3 [Homo sapiens]
Length = 575
Score = 44.3 bits (103), Expect = 8e-05
Identities = 26/101 (25%), Positives = 61/101 (60%), Gaps = 5/101 (4%)
Query: 41 KTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLKRAK 99
+T+A L+++ + +HN +E+ RR + +++L L+P D R ++LK +
Sbjct: 335 ETEAKALLKER-QKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKASV 393
Query: 100 VHIKKLEEQDRRALSIKEQ---LQQEHRFLKRRLEQLSVQS 137
+I+KL+++ +R+ ++ + L+Q +R L+ R+++L +Q+
Sbjct: 394 DYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQA 434
>gi|38156705 microphthalmia-associated transcription factor isoform
6 [Homo sapiens]
Length = 495
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/104 (26%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 39 REKTKA-AGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLK 96
RE T++ A + K + +HN +E+ RR + +++L L+P D R ++LK
Sbjct: 265 RELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILK 324
Query: 97 RAKVHIKKLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137
+ +I+KL+ + +RA + +++L+ +R L R+++L +Q+
Sbjct: 325 ASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQA 368
>gi|38156703 microphthalmia-associated transcription factor isoform
2 [Homo sapiens]
Length = 504
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/104 (26%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 39 REKTKA-AGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLK 96
RE T++ A + K + +HN +E+ RR + +++L L+P D R ++LK
Sbjct: 274 RELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILK 333
Query: 97 RAKVHIKKLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137
+ +I+KL+ + +RA + +++L+ +R L R+++L +Q+
Sbjct: 334 ASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQA 377
>gi|38156701 microphthalmia-associated transcription factor isoform
3 [Homo sapiens]
Length = 519
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/104 (26%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 39 REKTKA-AGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLK 96
RE T++ A + K + +HN +E+ RR + +++L L+P D R ++LK
Sbjct: 289 RELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILK 348
Query: 97 RAKVHIKKLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137
+ +I+KL+ + +RA + +++L+ +R L R+++L +Q+
Sbjct: 349 ASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQA 392
>gi|38156699 microphthalmia-associated transcription factor isoform
1 [Homo sapiens]
Length = 520
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/104 (26%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 39 REKTKA-AGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLK 96
RE T++ A + K + +HN +E+ RR + +++L L+P D R ++LK
Sbjct: 290 RELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILK 349
Query: 97 RAKVHIKKLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137
+ +I+KL+ + +RA + +++L+ +R L R+++L +Q+
Sbjct: 350 ASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQA 393
>gi|38156697 microphthalmia-associated transcription factor isoform
5 [Homo sapiens]
Length = 413
Score = 42.7 bits (99), Expect = 2e-04
Identities = 28/104 (26%), Positives = 59/104 (56%), Gaps = 5/104 (4%)
Query: 39 REKTKA-AGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLK 96
RE T++ A + K + +HN +E+ RR + +++L L+P D R ++LK
Sbjct: 183 RELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILK 242
Query: 97 RAKVHIKKLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137
+ +I+KL+ + +RA + +++L+ +R L R+++L +Q+
Sbjct: 243 ASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQA 286
>gi|4557755 microphthalmia-associated transcription factor isoform 4
[Homo sapiens]
Length = 419
Score = 41.6 bits (96), Expect = 5e-04
Identities = 25/97 (25%), Positives = 54/97 (55%), Gaps = 4/97 (4%)
Query: 45 AGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD-STRHTTLSLLKRAKVHIK 103
A + K + +HN +E+ RR + +++L L+P D R ++LK + +I+
Sbjct: 196 ARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGTILKASVDYIR 255
Query: 104 KLEEQDRRALSI---KEQLQQEHRFLKRRLEQLSVQS 137
KL+ + +RA + +++L+ +R L R+++L +Q+
Sbjct: 256 KLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQA 292
>gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens]
Length = 279
Score = 41.6 bits (96), Expect = 5e-04
Identities = 23/85 (27%), Positives = 49/85 (57%), Gaps = 6/85 (7%)
Query: 55 RSSHNELEKHRRAKLRLYLEQLKQLVP---LGPDSTRHTTLSLLKRAKVHIKKLEEQDRR 111
R+ HNE+E+ RR K+ ++ QL +++P T + +L +A +I++L + ++R
Sbjct: 170 RAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQR 229
Query: 112 ---ALSIKEQLQQEHRFLKRRLEQL 133
E+LQ ++ L++++E+L
Sbjct: 230 MQETFKEAERLQMDNELLRQQIEEL 254
>gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens]
Length = 346
Score = 41.6 bits (96), Expect = 5e-04
Identities = 23/85 (27%), Positives = 49/85 (57%), Gaps = 6/85 (7%)
Query: 55 RSSHNELEKHRRAKLRLYLEQLKQLVP---LGPDSTRHTTLSLLKRAKVHIKKLEEQDRR 111
R+ HNE+E+ RR K+ ++ QL +++P T + +L +A +I++L + ++R
Sbjct: 237 RAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQR 296
Query: 112 ---ALSIKEQLQQEHRFLKRRLEQL 133
E+LQ ++ L++++E+L
Sbjct: 297 MQETFKEAERLQMDNELLRQQIEEL 321
>gi|8922477 polymerase (RNA) III (DNA directed) polypeptide E [Homo
sapiens]
Length = 708
Score = 41.6 bits (96), Expect = 5e-04
Identities = 43/155 (27%), Positives = 66/155 (42%), Gaps = 30/155 (19%)
Query: 26 GYASVLPFDGDFAREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD 85
G+ +LP+DG+F ++K P+ + L +AKL +K+ +P PD
Sbjct: 397 GWEFILPYDGEF----------IKKHPDVVQRQHMLWTGIQAKLEKVYNLVKETMPKKPD 446
Query: 86 STRHTTLSLLKRAKVHIKKLEEQDRRALSIKEQLQQEHRFLKRRL----EQLSVQSVE-- 139
A+ L D+R K + QQ H L+R L EQL V +V
Sbjct: 447 ------------AQSGPAGLVCGDQRIQVAKTKAQQNHALLERELQRRKEQLRVPAVPPG 494
Query: 140 -RVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDS 173
R++ + S +D EQE + E M+ P L S
Sbjct: 495 VRIKEEPV-SEEGEEDEEQEAEEEPMDTSPSGLHS 528
>gi|19923312 v-myc myelocytomatosis viral related oncogene,
neuroblastoma derived [Homo sapiens]
Length = 464
Score = 40.4 bits (93), Expect = 0.001
Identities = 23/77 (29%), Positives = 42/77 (54%)
Query: 55 RSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRALS 114
R +HN LE+ RR LR L+ VP + + + +LK+A ++ L+ ++ + L
Sbjct: 383 RRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLL 442
Query: 115 IKEQLQQEHRFLKRRLE 131
KE+LQ + L +++E
Sbjct: 443 EKEKLQARQQQLLKKIE 459
>gi|24307933 transcription factor EB [Homo sapiens]
Length = 476
Score = 40.4 bits (93), Expect = 0.001
Identities = 39/156 (25%), Positives = 76/156 (48%), Gaps = 7/156 (4%)
Query: 28 ASVLPFDGDFAREKTKAAG-LVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPD- 85
+S P D RE T A + K + +HN +E+ RR + +++L L+P D
Sbjct: 209 SSSCPADLTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDL 268
Query: 86 STRHTTLSLLKRAKVHIKKLE---EQDRRALSIKEQLQQEHRFLKRRLEQLSVQS-VERV 141
R ++LK + +I++++ ++ R + +L+ ++ L R+++L +Q+ V +
Sbjct: 269 DVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGL 328
Query: 142 RTDSTGSAVSTDDSEQEVDIE-GMEFGPGELDSVGS 176
T S + ++Q V E E GPGE +G+
Sbjct: 329 PTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGA 364
>gi|114431248 hypothetical protein LOC205717 [Homo sapiens]
Length = 2245
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/86 (24%), Positives = 50/86 (58%), Gaps = 3/86 (3%)
Query: 54 NRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRAL 113
NR +HN +E+HR+ K+ + ++ +L+P P + + + +L +A +I +L+ Q+ L
Sbjct: 19 NRETHNAVERHRKKKINAGINRIGELIPCSP-ALKQSKNMILDQAFKYITELKRQNDELL 77
Query: 114 --SIKEQLQQEHRFLKRRLEQLSVQS 137
+ +E + L+++LE++ ++
Sbjct: 78 LNGGNNEQAEEIKKLRKQLEEIQKEN 103
>gi|27477113 sterol regulatory element-binding transcription factor
2 [Homo sapiens]
Length = 1141
Score = 40.0 bits (92), Expect = 0.001
Identities = 40/150 (26%), Positives = 72/150 (48%), Gaps = 29/150 (19%)
Query: 50 KAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQD 109
K R++HN +EK R+ + + +LK LV +G D+ H + +L++A +IK L++
Sbjct: 327 KEGERRTTHNIIEKRYRSSINDKIIELKDLV-MGTDAKMHKS-GVLRKAIDYIKYLQQ-- 382
Query: 110 RRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPG 169
+ +L+QE+ LK L+ Q + ++ GS V + EVD++ +F
Sbjct: 383 -----VNHKLRQENMVLK-----LANQKNKLLKGIDLGSLV-----DNEVDLKIEDFNQN 427
Query: 170 ELDSVGSSSDADDHYSLQSGTGGDSGFGPH 199
L +SD +G +GF P+
Sbjct: 428 VLLMSPPASD----------SGSQAGFSPY 447
>gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens]
Length = 310
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/88 (29%), Positives = 51/88 (57%), Gaps = 12/88 (13%)
Query: 55 RSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLS------LLKRAKVHIKKLEEQ 108
R+ HNE+E+ RR K+ ++ QL +++ PD + +T S +L +A +I++L +
Sbjct: 201 RAQHNEVERRRRDKINNWIVQLSKII---PDCSMESTKSGQSKGGILSKACDYIQELRQS 257
Query: 109 DRR---ALSIKEQLQQEHRFLKRRLEQL 133
+ R L +QLQ ++ L++++E L
Sbjct: 258 NHRLSEELQGLDQLQLDNDVLRQQVEDL 285
>gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens]
Length = 251
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/88 (29%), Positives = 51/88 (57%), Gaps = 12/88 (13%)
Query: 55 RSSHNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLS------LLKRAKVHIKKLEEQ 108
R+ HNE+E+ RR K+ ++ QL +++ PD + +T S +L +A +I++L +
Sbjct: 142 RAQHNEVERRRRDKINNWIVQLSKII---PDCSMESTKSGQSKGGILSKACDYIQELRQS 198
Query: 109 DRR---ALSIKEQLQQEHRFLKRRLEQL 133
+ R L +QLQ ++ L++++E L
Sbjct: 199 NHRLSEELQGLDQLQLDNDVLRQQVEDL 226
>gi|239047343 spermatogenesis and oogenesis specific basic
helix-loop-helix 2 [Homo sapiens]
Length = 425
Score = 38.9 bits (89), Expect = 0.003
Identities = 39/159 (24%), Positives = 71/159 (44%), Gaps = 13/159 (8%)
Query: 58 HNELEKHRRAKLRLYLEQLKQLVPLGPDSTRHTTLSLLKRAKVHIKKLEEQDRRAL--SI 115
H+ EK RR +++ EQL+ L+P ++ S+L+ ++K + E+ A+ I
Sbjct: 206 HSSKEKLRRERIKYCCEQLRTLLPY-VKGRKNDAASVLEATVDYVKYIREKISPAVMAQI 264
Query: 116 KEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEFGPGELDSVG 175
E LQ RF K++ + + V S +ST E+ G++F +
Sbjct: 265 TEALQSNMRFCKKQQTPIELSLPGTVMAQRENSVMSTYSPER-----GLQFLTNTCWNGC 319
Query: 176 SSSDA----DDHYSLQSGTGGDSGFG-PHCRRLGRPALS 209
S+ DA D+ + S + ++ G P+ + ALS
Sbjct: 320 STPDAESSLDEAVRVPSSSASENAIGDPYKTHISSAALS 358
>gi|7705415 hook homolog 1 [Homo sapiens]
Length = 728
Score = 37.7 bits (86), Expect = 0.007
Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 9/117 (7%)
Query: 53 NNRSSHNELEKHRRAKLRL--YLEQLKQL-VPLGPDSTRHTTLSLLKRAKVHIKKLEEQD 109
N S EL+K A+ +L Y Q++ L V L +S R TL+ +K+LEE+
Sbjct: 353 NTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKRADTLAF------EMKRLEEKH 406
Query: 110 RRALSIKEQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVSTDDSEQEVDIEGMEF 166
L KE+L ++ LK E+L V++ + T ++ + +I +E+
Sbjct: 407 EALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEY 463
>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
isoform b [Homo sapiens]
Length = 582
Score = 37.4 bits (85), Expect = 0.009
Identities = 22/67 (32%), Positives = 39/67 (58%), Gaps = 4/67 (5%)
Query: 40 EKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVP-LGPDSTRHTTLSLLKRA 98
E T+ G ++ A R +H+++EK RR K+ ++++L LVP S + L++L+ A
Sbjct: 19 EYTEHQGRIKNA---REAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMA 75
Query: 99 KVHIKKL 105
H+K L
Sbjct: 76 VQHMKTL 82
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,818,358
Number of Sequences: 37866
Number of extensions: 342113
Number of successful extensions: 1965
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 170
Number of HSP's that attempted gapping in prelim test: 1683
Number of HSP's gapped (non-prelim): 451
length of query: 209
length of database: 18,247,518
effective HSP length: 98
effective length of query: 111
effective length of database: 14,536,650
effective search space: 1613568150
effective search space used: 1613568150
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.