Guide to the Human Genome
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Search of human proteins with 5453565

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens]
         (520 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens]        1028   0.0  
gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens]        1013   0.0  
gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens]      1012   0.0  
gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens]        1012   0.0  
gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]           378   e-105
gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens]          196   6e-50
gi|144226234 metastasis suppressor 1 [Homo sapiens]                    70   5e-12
gi|46195763 metastasis suppressor 1-like [Homo sapiens]                60   4e-09
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]                49   9e-06
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]                49   9e-06
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]          43   8e-04
gi|7706706 sorting nexin 9 [Homo sapiens]                              43   8e-04
gi|46094081 development and differentiation enhancing factor 1 [...    41   0.002
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    41   0.003
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    41   0.003
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    41   0.003
gi|5453710 LIM and SH3 protein 1 [Homo sapiens]                        40   0.004
gi|148747351 protein kinase C and casein kinase substrate in neu...    40   0.004
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ...    40   0.005
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ...    40   0.005
gi|29648315 small G protein signaling modulator 3 [Homo sapiens]       39   0.012
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]                     39   0.015
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]                     39   0.015
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa...    38   0.026
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa...    38   0.026
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    37   0.033
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]           37   0.033
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]           37   0.033
gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]     37   0.044
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...    37   0.044

>gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens]
          Length = 520

 Score = 1028 bits (2658), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 1   MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
           MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
Sbjct: 1   MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60

Query: 61  ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
           ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
Sbjct: 61  ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120

Query: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
           KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
Sbjct: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180

Query: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
           DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
Sbjct: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240

Query: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
           VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
Sbjct: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300

Query: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
           GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
Sbjct: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360

Query: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
           LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
Sbjct: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420

Query: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
           TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
Sbjct: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480

Query: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMSSADVEVARF 520
           QTASGFKQRPYSVAVPAFSQGLDDYGARSMSSADVEVARF
Sbjct: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMSSADVEVARF 520


>gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens]
          Length = 521

 Score = 1013 bits (2620), Expect = 0.0
 Identities = 512/512 (100%), Positives = 512/512 (100%)

Query: 1   MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
           MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
Sbjct: 1   MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60

Query: 61  ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
           ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
Sbjct: 61  ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120

Query: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
           KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
Sbjct: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180

Query: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
           DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
Sbjct: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240

Query: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
           VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
Sbjct: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300

Query: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
           GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
Sbjct: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360

Query: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
           LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
Sbjct: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420

Query: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
           TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
Sbjct: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480

Query: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMSS 512
           QTASGFKQRPYSVAVPAFSQGLDDYGARSMSS
Sbjct: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMSS 512


>gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens]
          Length = 534

 Score = 1012 bits (2616), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
           MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
Sbjct: 1   MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60

Query: 61  ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
           ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
Sbjct: 61  ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120

Query: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
           KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
Sbjct: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180

Query: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
           DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
Sbjct: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240

Query: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
           VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
Sbjct: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300

Query: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
           GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
Sbjct: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360

Query: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
           LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
Sbjct: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420

Query: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
           TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
Sbjct: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480

Query: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMS 511
           QTASGFKQRPYSVAVPAFSQGLDDYGARSMS
Sbjct: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMS 511


>gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens]
          Length = 552

 Score = 1012 bits (2616), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60
           MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG
Sbjct: 1   MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMG 60

Query: 61  ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120
           ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL
Sbjct: 61  ELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAAL 120

Query: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180
           KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS
Sbjct: 121 KKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVS 180

Query: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240
           DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA
Sbjct: 181 DGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERA 240

Query: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300
           VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN
Sbjct: 241 VQLMQQVASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMN 300

Query: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360
           GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT
Sbjct: 301 GVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKT 360

Query: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420
           LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK
Sbjct: 361 LPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEK 420

Query: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480
           TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA
Sbjct: 421 TKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDKDDLAIPPPDYGAASRAFPA 480

Query: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMS 511
           QTASGFKQRPYSVAVPAFSQGLDDYGARSMS
Sbjct: 481 QTASGFKQRPYSVAVPAFSQGLDDYGARSMS 511


>gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
          Length = 511

 Score =  378 bits (971), Expect = e-105
 Identities = 199/493 (40%), Positives = 299/493 (60%), Gaps = 47/493 (9%)

Query: 7   EEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASES 66
           EE++RLTE+ Y+ +MEQFNP LRN I +GKNYEKA+  +  A K Y+D + K+GE+A+ S
Sbjct: 6   EEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGS 65

Query: 67  QGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTE 126
             S ELG VL +++  H+++   L+E  K FH E++ +LE+K+ELD +Y++A LK+YQTE
Sbjct: 66  PVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTE 125

Query: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTA 186
            ++K ++L+K QAELKK+R+KSQGS+N  KY  KE++Y++ ++++Q E++ +++DG K A
Sbjct: 126 HKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEA 185

Query: 187 LTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQ 246
           L EE+RRFCFLV+K C  A +   YH +  ELL  KLP WQ+ C D  K+PE+ + ++++
Sbjct: 186 LLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEE 245

Query: 247 VASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPD 306
           + +                      P + P+   P+ +P + R +               
Sbjct: 246 IKT----------------------PASTPVSGTPQASPMIERSNVVR------------ 271

Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSN-TLPVRKSVTPKNSYATTENKTLPRSS 365
            +DY   +      P + S     S L D ++N       S    NS  T+E+ +L RS 
Sbjct: 272 -KDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSV 330

Query: 366 SMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRG 425
           S+A GL    + +VK IF H AG N TLLSF +GD+ITLL+PE +DGW YGE + +K RG
Sbjct: 331 SVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARG 390

Query: 426 WFPFSYTRVLDSDGSDRLHM---SLQQGKSSSTGNLLDKDDLAIPPPDY------GAAS- 475
           WFP SYT++L+ + ++ + +   S    +S ST NL +   + IPPPDY      GAA+ 
Sbjct: 391 WFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAAD 450

Query: 476 -RAFPAQTASGFK 487
            RA  A+T S FK
Sbjct: 451 RRADSARTTSTFK 463


>gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens]
          Length = 529

 Score =  196 bits (497), Expect = 6e-50
 Identities = 123/430 (28%), Positives = 219/430 (50%), Gaps = 49/430 (11%)

Query: 7   EEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASES 66
           ++ +R T  +YK+IMEQFNP+L N + +G NY +A   ++ AA+ YF A+ K+GE A +S
Sbjct: 6   DQFYRSTMAIYKSIMEQFNPALENLVYLGNNYLRAFHALSEAAEVYFSAIQKIGERALQS 65

Query: 67  QGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTE 126
             S+ LG++L QM++  R + + LE ++++FH  LL  +E+  +LD +++  + + Y+ E
Sbjct: 66  PTSQILGEILVQMSDTQRHLNSDLEVVVQTFHGGLLQHMEKNTKLDMQFIKDSRQHYELE 125

Query: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTA 186
            R +   L+KC +EL ++ +K   +    K         ++++    +++ +VS+  + A
Sbjct: 126 YRHRAANLEKCMSELWRMERKRDKNVREMK---------ESVNRLHAQMQAFVSESQRAA 176

Query: 187 LTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQ 246
             EE+RR+ FL EK   ++     +  + + +L  ++ LW++  ++ S+ P RA      
Sbjct: 177 ELEEKRRYRFLAEKHLLLSNTFLQFFGRARGMLQNRVLLWKEQ-SEASRSPSRA------ 229

Query: 247 VASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPD 306
             S G   P+          +  P P  +  P   ++ P   R   + S+P     +G  
Sbjct: 230 -HSPGLLGPA----------LGPPYPSGRLTPTCLDMPP---RPLGEFSSPRSRHGSGSY 275

Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSS 366
           G +         A+P S   P  +S         LP   S +   S +   +++      
Sbjct: 276 GTE-------PDARPASQLEPDRRS---------LPRTPSASSLYSGSAQSSRSNSFGER 319

Query: 367 MAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGW 426
              G    G  RV+A+ SH+ G N TLL F  GD++ +LVPEA++GW YG+ E +   GW
Sbjct: 320 PGGG---GGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLEGSSASGW 376

Query: 427 FPFSYTRVLD 436
           FP +Y + L+
Sbjct: 377 FPEAYVKALE 386


>gi|144226234 metastasis suppressor 1 [Homo sapiens]
          Length = 755

 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 83/379 (21%), Positives = 164/379 (43%), Gaps = 35/379 (9%)

Query: 16  VYKTIMEQFN---PSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQG-SKE 71
           +++TI+       P   +FI      +  L     AA  + DA  K+ ++A+ ++G ++E
Sbjct: 15  LFQTIISDMKGSYPVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTRE 74

Query: 72  LGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKG 131
           +G  L +M   HR I+ +L +   +  + L+  L++++E   +  +   K +  E +   
Sbjct: 75  IGSALTRMCMRHRSIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKAR 134

Query: 132 DALDKCQAELKKLRKKS-QGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEE 190
             + K  ++  KL+KK+ +G  + Q   D  LQ    +++K   LE       + AL EE
Sbjct: 135 QEIKKKSSDTLKLQKKAKKGRGDIQPQLDSALQ---DVNDKYLLLEETEKQAVRKALIEE 191

Query: 191 RRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQV--- 247
           R RFC  +     V +   +   +   L      L +    DP K+P  + Q++  +   
Sbjct: 192 RGRFCTFISMLRPVIEEEISMLGEITHLQTISEDL-KSLTMDPHKLPSSSEQVILDLKGS 250

Query: 248 ------------ASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQES 295
                        S   +  S++ +S +++  SD          P     +     AQ++
Sbjct: 251 DYSWSYQTPPSSPSTTMSRKSSVCSSLNSVNSSDSRSSGSHSHSPSSHYRYRSSNLAQQA 310

Query: 296 TPIMNGVTGPDGEDYSPWADRKAAQPKSLS--PPQSQSKLSDSYSN-TLPVRKSVTPKNS 352
              ++ V+  D    S +  + A Q KS S  PP++ ++LS+ +S+ +L     V P  +
Sbjct: 311 PVRLSSVSSHD----SGFISQDAFQSKSPSPMPPEAPNQLSNGFSHYSLSSESHVGPTGA 366

Query: 353 ----YATTENKTLPRSSSM 367
               +    ++ LPR +S+
Sbjct: 367 GLFPHCLPASRLLPRVTSV 385


>gi|46195763 metastasis suppressor 1-like [Homo sapiens]
          Length = 747

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 80/381 (20%), Positives = 149/381 (39%), Gaps = 36/381 (9%)

Query: 21  MEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGS-KELGDVLFQM 79
           M+   P   +F +        L     AA  + DA  K+ ++A+ ++G+ +++G  L +M
Sbjct: 22  MKSSYPIWEDFNSKATKLHSQLRTTVLAAVAFLDAFQKVADMATNTRGATRDIGSALTRM 81

Query: 80  AEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQA 139
              HR I+ +L +   +    L+  L++++E   +  +   K +  E +     + K  +
Sbjct: 82  CMRHRSIETKLRQFTNALLESLINPLQERIEDWKKAANQLDKDHAKEYKRARHEIKKKSS 141

Query: 140 ELKKLRKKSQ----GSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFC 195
           +  KL+KK++    G  + Q   D  LQ    +++    LE       + AL EER RFC
Sbjct: 142 DTLKLQKKARKELLGKGDLQPQLDSALQ---DVNDMYLLLEETEKQAVRRALIEERGRFC 198

Query: 196 FLVEKQCAVAKNSAAYHSKGKEL--LAQKLPLWQQACADPSKIPERAVQLMQQV------ 247
             +     V         +   L  +   L +     A+P K+P  + Q+++ +      
Sbjct: 199 TFITFLQPVVNGELTMLGEITHLQGIIDDLVV---LTAEPHKLPPASEQVIKDLKGSDYS 255

Query: 248 -------------ASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQE 294
                        +S  +++ SA S+S S      P PG      P     +        
Sbjct: 256 WSYQTPPSSPSSSSSRKSSMCSAPSSSSSAKGGGAPWPGGAQTYSPSSTCRYRSLAQPAT 315

Query: 295 STPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQ--SQSKLSDSYSNTLPVRKSVTPKNS 352
           +T  ++ V+  D    S   D   ++P S  P    SQ   S + S      +SV+  +S
Sbjct: 316 TTARLSSVSSHDSGFVS--QDATYSKPPSPMPSDITSQKSSSSASSEASETCQSVSECSS 373

Query: 353 YATTENKTLPRSSSMAAGLER 373
             +  +K         A L+R
Sbjct: 374 PTSDWSKVGSHEQPSGATLQR 394


>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
          Length = 1220

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 93/435 (21%), Positives = 177/435 (40%), Gaps = 83/435 (19%)

Query: 78  QMAEVHRQIQNQLEEMLKSFHNEL--LTQLEQKVELDSRYLSAALKKYQTEQRSKGDALD 135
           Q+ EV ++ +++L+E +  F+N+L  L ++  K +L  +    A +  Q EQ  K   L+
Sbjct: 585 QLDEVEKETRSKLQE-IDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELE 643

Query: 136 KCQAE------------LKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGY 183
           K + E            L+ ++++ +  +  + + +++L+  +++  K GE       G 
Sbjct: 644 KQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGE-----EKGK 698

Query: 184 KTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQL 243
           + A  +++    F   ++ A     A + +      A+K PL   A  +   +  RA+  
Sbjct: 699 QEA--QDKLGRLFHQHQEPAKPAVQAPWST------AEKGPLTISAQENVKVVYYRALYP 750

Query: 244 MQQVASNGATL-PSALSASKSNLVISD-------------------PIPGAKPLP---VP 280
            +  + +  T+ P  +   K   V                      P   A+ +P   VP
Sbjct: 751 FESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVP 810

Query: 281 PELAPFVGRMSAQ------ESTPIMNGVTGPDGEDY-SPWADRKAAQPKSLSPPQ----- 328
             + P     SA         TP    VT  +     + WAD  +  P S +        
Sbjct: 811 APVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNW 870

Query: 329 ----SQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFS 384
               +Q  L+   +  L  R + TP  +  ++ +  L +   +         ++ +A++ 
Sbjct: 871 DAWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEG-------LQAQALYP 923

Query: 385 -HAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRL 443
             A  DN   L+F + D+IT+L  E +D W +GE +  K  GWFP SY +++   G  R 
Sbjct: 924 WRAKKDNH--LNFNKNDVITVL--EQQDMWWFGEVQGQK--GWFPKSYVKLI--SGPIRK 975

Query: 444 HMSLQQGKSSSTGNL 458
             S+  G S S  +L
Sbjct: 976 STSMDSGSSESPASL 990



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 16/124 (12%)

Query: 342  PVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDL 401
            P+RKS T  +S ++    +L R +S AA    +G   + A++++ + +   L +F++GD+
Sbjct: 972  PIRKS-TSMDSGSSESPASLKRVASPAAKPVVSGEEFI-AMYTYESSEQGDL-TFQQGDV 1028

Query: 402  ITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDK 461
            I L+  +  D W     +K    G FP +Y R+ DS+GS         G +  TG+L  K
Sbjct: 1029 I-LVTKKDGDWWTGTVGDKA---GVFPSNYVRLKDSEGS---------GTAGKTGSLGKK 1075

Query: 462  DDLA 465
             ++A
Sbjct: 1076 PEIA 1079



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 33/140 (23%), Positives = 66/140 (47%), Gaps = 10/140 (7%)

Query: 57  VKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLK-SFHNELLTQLEQKVE---LD 112
           +++ E+    Q  +E   +L ++    + + +QL+++ + S H + L  L++ +E   L 
Sbjct: 519 LRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELA 578

Query: 113 SRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQ 172
            ++L   L + + E RSK   +D    +LK+LR +    +  QK    E + +     KQ
Sbjct: 579 RQHLRDQLDEVEKETRSKLQEIDIFNNQLKELR-EIHNKQQLQKQKSMEAERL-----KQ 632

Query: 173 GELENYVSDGYKTALTEERR 192
            E E  + +  K     +RR
Sbjct: 633 KEQERKIIELEKQKEEAQRR 652



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 11/146 (7%)

Query: 56  LVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRY 115
           L K  +   E Q  ++      + AE  R+ + + +E  +    EL  QLE++ EL+ + 
Sbjct: 365 LEKRRQALLEQQRKEQERLAQLERAEQERK-ERERQEQERKRQLELEKQLEKQRELERQR 423

Query: 116 LSAALKKYQTEQRSKGDALDKCQAELKKLRKK---SQGSKNPQ-----KYSDKELQY-ID 166
                K+ +  + +K +   + Q E ++ R++   +Q +K  +     K   K L++ ++
Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELE 483

Query: 167 AISNKQGELENYVSDGYKTALTEERR 192
           A+++K+ +LE  + D  +  LT +R+
Sbjct: 484 ALNDKKHQLEGKLQD-IRCRLTTQRQ 508


>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
          Length = 1721

 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 93/435 (21%), Positives = 177/435 (40%), Gaps = 83/435 (19%)

Query: 78  QMAEVHRQIQNQLEEMLKSFHNEL--LTQLEQKVELDSRYLSAALKKYQTEQRSKGDALD 135
           Q+ EV ++ +++L+E +  F+N+L  L ++  K +L  +    A +  Q EQ  K   L+
Sbjct: 585 QLDEVEKETRSKLQE-IDIFNNQLKELREIHNKQQLQKQKSMEAERLKQKEQERKIIELE 643

Query: 136 KCQAE------------LKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGY 183
           K + E            L+ ++++ +  +  + + +++L+  +++  K GE       G 
Sbjct: 644 KQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHEEEKLKREESVKKKDGE-----EKGK 698

Query: 184 KTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQL 243
           + A  +++    F   ++ A     A + +      A+K PL   A  +   +  RA+  
Sbjct: 699 QEA--QDKLGRLFHQHQEPAKPAVQAPWST------AEKGPLTISAQENVKVVYYRALYP 750

Query: 244 MQQVASNGATL-PSALSASKSNLVISD-------------------PIPGAKPLP---VP 280
            +  + +  T+ P  +   K   V                      P   A+ +P   VP
Sbjct: 751 FESRSHDEITIQPGDIVMVKGEWVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEVP 810

Query: 281 PELAPFVGRMSAQ------ESTPIMNGVTGPDGEDY-SPWADRKAAQPKSLSPPQ----- 328
             + P     SA         TP    VT  +     + WAD  +  P S +        
Sbjct: 811 APVKPVTDSTSAPAPKLALRETPAPLAVTSSEPSTTPNNWADFSSTWPTSTNEKPETDNW 870

Query: 329 ----SQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFS 384
               +Q  L+   +  L  R + TP  +  ++ +  L +   +         ++ +A++ 
Sbjct: 871 DAWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEG-------LQAQALYP 923

Query: 385 -HAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRL 443
             A  DN   L+F + D+IT+L  E +D W +GE +  K  GWFP SY +++   G  R 
Sbjct: 924 WRAKKDNH--LNFNKNDVITVL--EQQDMWWFGEVQGQK--GWFPKSYVKLI--SGPIRK 975

Query: 444 HMSLQQGKSSSTGNL 458
             S+  G S S  +L
Sbjct: 976 STSMDSGSSESPASL 990



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 37/124 (29%), Positives = 65/124 (52%), Gaps = 16/124 (12%)

Query: 342  PVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDL 401
            P+RKS T  +S ++    +L R +S AA    +G   + A++++ + +   L +F++GD+
Sbjct: 972  PIRKS-TSMDSGSSESPASLKRVASPAAKPVVSGEEFI-AMYTYESSEQGDL-TFQQGDV 1028

Query: 402  ITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQGKSSSTGNLLDK 461
            I L+  +  D W     +K    G FP +Y R+ DS+GS         G +  TG+L  K
Sbjct: 1029 I-LVTKKDGDWWTGTVGDKA---GVFPSNYVRLKDSEGS---------GTAGKTGSLGKK 1075

Query: 462  DDLA 465
             ++A
Sbjct: 1076 PEIA 1079



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 33/140 (23%), Positives = 66/140 (47%), Gaps = 10/140 (7%)

Query: 57  VKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLK-SFHNELLTQLEQKVE---LD 112
           +++ E+    Q  +E   +L ++    + + +QL+++ + S H + L  L++ +E   L 
Sbjct: 519 LRIAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNSLHRDSLVTLKRALEAKELA 578

Query: 113 SRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQ 172
            ++L   L + + E RSK   +D    +LK+LR +    +  QK    E + +     KQ
Sbjct: 579 RQHLRDQLDEVEKETRSKLQEIDIFNNQLKELR-EIHNKQQLQKQKSMEAERL-----KQ 632

Query: 173 GELENYVSDGYKTALTEERR 192
            E E  + +  K     +RR
Sbjct: 633 KEQERKIIELEKQKEEAQRR 652



 Score = 29.6 bits (65), Expect = 7.0
 Identities = 33/146 (22%), Positives = 72/146 (49%), Gaps = 11/146 (7%)

Query: 56  LVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRY 115
           L K  +   E Q  ++      + AE  R+ + + +E  +    EL  QLE++ EL+ + 
Sbjct: 365 LEKRRQALLEQQRKEQERLAQLERAEQERK-ERERQEQERKRQLELEKQLEKQRELERQR 423

Query: 116 LSAALKKYQTEQRSKGDALDKCQAELKKLRKK---SQGSKNPQ-----KYSDKELQY-ID 166
                K+ +  + +K +   + Q E ++ R++   +Q +K  +     K   K L++ ++
Sbjct: 424 EEERRKEIERREAAKRELERQRQLEWERNRRQELLNQRNKEQEDIVVLKAKKKTLEFELE 483

Query: 167 AISNKQGELENYVSDGYKTALTEERR 192
           A+++K+ +LE  + D  +  LT +R+
Sbjct: 484 ALNDKKHQLEGKLQD-IRCRLTTQRQ 508


>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
          Length = 476

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 25/63 (39%), Positives = 36/63 (57%), Gaps = 4/63 (6%)

Query: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLL-VPEARDGWHYGESEKTKMRGWFPFSYTRVLD 436
           R + ++  +   +   L F  G+LITLL VP+   GW  GE E   +RGWFP SY ++L+
Sbjct: 5   RCRTLYPFSGERHGQGLRFAAGELITLLQVPDG--GWWEGEKEDG-LRGWFPASYVQLLE 61

Query: 437 SDG 439
             G
Sbjct: 62  KPG 64


>gi|7706706 sorting nexin 9 [Homo sapiens]
          Length = 595

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%)

Query: 378 RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVLDS 437
           + + ++  AA   +  L+  EG++IT+  P+   GW  G + K + RG  P  Y  +L S
Sbjct: 4   KARVMYDFAAEPGNNELTVNEGEIITITNPDVGGGWLEGRNIKGE-RGLVPTDYVEILPS 62

Query: 438 DGSDR 442
           DG D+
Sbjct: 63  DGKDQ 67


>gi|46094081 development and differentiation enhancing factor 1 [Homo
            sapiens]
          Length = 1129

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 37/166 (22%), Positives = 64/166 (38%), Gaps = 20/166 (12%)

Query: 270  PIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQS 329
            P P  K LP  P+L   + +    + +P                   KA QP  ++    
Sbjct: 982  PKPQMKDLPPKPQLGDLLAKSQTGDVSP-------------------KAQQPSEVTLKSH 1022

Query: 330  QSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGD 389
               LS +  +   ++K  +  ++  T      P          +N   RVK I+   A D
Sbjct: 1023 PLDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPRKINTGKNKVRRVKTIYDCQA-D 1081

Query: 390  NSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVL 435
            N   L+F EG++I +   E ++ W      + + +G FP S+  +L
Sbjct: 1082 NDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHIL 1127


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 12/137 (8%)

Query: 307  GEDYSPWADRKAAQPKSLSPPQSQSKL-----SDSYSNTLPVRKSVTPKNSYATTENKTL 361
            GE+Y       + +P  L+  + +  L      + ++ ++  R  + P N     + ++ 
Sbjct: 956  GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESF 1015

Query: 362  PRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESE-- 419
              +S   A    N +  +  + S      S  LS   G LI L++ +   GW  GE +  
Sbjct: 1016 GSASKSGAS---NKKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQAR 1071

Query: 420  -KTKMRGWFPFSYTRVL 435
             K + +GWFP S+ ++L
Sbjct: 1072 GKKRQKGWFPASHVKLL 1088



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 9/123 (7%)

Query: 314 ADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLER 373
           A   +++P S + P S +   +   + L V  S   K+++  T +   P S S   G  +
Sbjct: 813 ATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVS---PGSVSPIHGQGQ 869

Query: 374 N-GRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYT 432
               ++ +A+ S  A  ++ L +F + D+IT+L  E ++ W +GE      RGWFP SY 
Sbjct: 870 VVENLKAQALCSWTAKKDNHL-NFSKHDIITVL--EQQENWWFGEVHGG--RGWFPKSYV 924

Query: 433 RVL 435
           +++
Sbjct: 925 KII 927



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 5/72 (6%)

Query: 378  RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRV-LD 436
            +V A++ +AA +N   LSF +G LI ++  +  D W   + E   + G FP +Y ++  D
Sbjct: 1104 QVIAMYDYAA-NNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTD 1159

Query: 437  SDGSDRLHMSLQ 448
            SD S +    LQ
Sbjct: 1160 SDPSQQWCADLQ 1171


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 12/137 (8%)

Query: 307  GEDYSPWADRKAAQPKSLSPPQSQSKL-----SDSYSNTLPVRKSVTPKNSYATTENKTL 361
            GE+Y       + +P  L+  + +  L      + ++ ++  R  + P N     + ++ 
Sbjct: 983  GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESF 1042

Query: 362  PRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESE-- 419
              +S   A    N +  +  + S      S  LS   G LI L++ +   GW  GE +  
Sbjct: 1043 GSASKSGAS---NKKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQAR 1098

Query: 420  -KTKMRGWFPFSYTRVL 435
             K + +GWFP S+ ++L
Sbjct: 1099 GKKRQKGWFPASHVKLL 1115



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 9/123 (7%)

Query: 314 ADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLER 373
           A   +++P S + P S +   +   + L V  S   K+++  T +   P S S   G  +
Sbjct: 840 ATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVS---PGSVSPIHGQGQ 896

Query: 374 N-GRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYT 432
               ++ +A+ S  A  ++ L +F + D+IT+L  E ++ W +GE      RGWFP SY 
Sbjct: 897 VVENLKAQALCSWTAKKDNHL-NFSKHDIITVL--EQQENWWFGEVHGG--RGWFPKSYV 951

Query: 433 RVL 435
           +++
Sbjct: 952 KII 954



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 5/72 (6%)

Query: 378  RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRV-LD 436
            +V A++ +AA +N   LSF +G LI ++  +  D W   + E   + G FP +Y ++  D
Sbjct: 1131 QVIAMYDYAA-NNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTD 1186

Query: 437  SDGSDRLHMSLQ 448
            SD S +    LQ
Sbjct: 1187 SDPSQQWCADLQ 1198


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/137 (22%), Positives = 59/137 (43%), Gaps = 12/137 (8%)

Query: 307  GEDYSPWADRKAAQPKSLSPPQSQSKL-----SDSYSNTLPVRKSVTPKNSYATTENKTL 361
            GE+Y       + +P  L+  + +  L      + ++ ++  R  + P N     + ++ 
Sbjct: 983  GEEYIALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESF 1042

Query: 362  PRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESE-- 419
              +S   A    N +  +  + S      S  LS   G LI L++ +   GW  GE +  
Sbjct: 1043 GSASKSGAS---NKKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQAR 1098

Query: 420  -KTKMRGWFPFSYTRVL 435
             K + +GWFP S+ ++L
Sbjct: 1099 GKKRQKGWFPASHVKLL 1115



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 34/123 (27%), Positives = 62/123 (50%), Gaps = 9/123 (7%)

Query: 314 ADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNSYATTENKTLPRSSSMAAGLER 373
           A   +++P S + P S +   +   + L V  S   K+++  T +   P S S   G  +
Sbjct: 840 ATSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVS---PGSVSPIHGQGQ 896

Query: 374 N-GRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYT 432
               ++ +A+ S  A  ++ L +F + D+IT+L  E ++ W +GE      RGWFP SY 
Sbjct: 897 VVENLKAQALCSWTAKKDNHL-NFSKHDIITVL--EQQENWWFGEVHGG--RGWFPKSYV 951

Query: 433 RVL 435
           +++
Sbjct: 952 KII 954



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 5/72 (6%)

Query: 378  RVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRV-LD 436
            +V A++ +AA +N   LSF +G LI ++  +  D W   + E   + G FP +Y ++  D
Sbjct: 1131 QVIAMYDYAA-NNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTD 1186

Query: 437  SDGSDRLHMSLQ 448
            SD S +    LQ
Sbjct: 1187 SDPSQQWCADLQ 1198


>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
          Length = 261

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 21/61 (34%), Positives = 34/61 (55%), Gaps = 2/61 (3%)

Query: 375 GRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRV 434
           G  R +A++ ++A D   + SF++GD I + V +  DGW YG  E+T   G  P +Y   
Sbjct: 203 GGKRYRAVYDYSAADEDEV-SFQDGDTI-VNVQQIDDGWMYGTVERTGDTGMLPANYVEA 260

Query: 435 L 435
           +
Sbjct: 261 I 261


>gi|148747351 protein kinase C and casein kinase substrate in
           neurons 2 [Homo sapiens]
          Length = 486

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 80/356 (22%), Positives = 135/356 (37%), Gaps = 61/356 (17%)

Query: 106 EQKVELDSRYLSAALKKYQTEQRSK-GDALDKCQAELKKLRKKSQGS------------- 151
           E+K+ +     S A      EQ  K  D ++KC+ ++ K ++K + S             
Sbjct: 165 EEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYME 224

Query: 152 ------KNPQKYSDKELQYI-DAISNKQGELENYVSDGYKTAL--TEERRRFCFLVEKQC 202
                 +  Q++ +K L++  + +   Q  L+     GYK      E+  R    VE   
Sbjct: 225 NMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVAGYKAIYHDLEQSIRAADAVED-- 282

Query: 203 AVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQVASNGATLPSALSASK 262
              +   A H  G   +A   P +++  AD ++   R  +   + A++G TL        
Sbjct: 283 --LRWFRANHGPG---MAMNWPQFEEWSADLNRTLSRREK---KKATDGVTLTGINQTGD 334

Query: 263 SNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPK 322
            +L    P   +  L VP    P     S     P  +      G   S   D KA    
Sbjct: 335 QSL----PSKPSSTLNVPSN--PAQSAQSQSSYNPFED--EDDTGSTVSEKDDTKAKNVS 386

Query: 323 SLSPPQSQ-SKLSDSYSNTLPVRKSVTPKNSYATTE--NKTLPRSSSMAAGLERNGRMRV 379
           S    QS  +  SD  SN           N +++T+    + P      +G E    +RV
Sbjct: 387 SYEKTQSYPTDWSDDESN-----------NPFSSTDANGDSNPFDDDATSGTE----VRV 431

Query: 380 KAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSYTRVL 435
           +A++ +  G     LSFK GD +T +  E   GW  G  +  ++ G +P +Y   +
Sbjct: 432 RALYDYE-GQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQV-GLYPANYVEAI 485


>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
           sapiens]
          Length = 628

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 8/99 (8%)

Query: 341 LPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGD 400
           LPV K++  K    T      P SS          +   K IF + A  N   L+ KEGD
Sbjct: 201 LPVEKTIGKKLPATTAT----PDSSKTEMDSRTKSKDYCKVIFPYEA-QNDDELTIKEGD 255

Query: 401 LITLLVPEARD-GWHYGESEKTKMRGWFPFSYTRVLDSD 438
           ++TL+  +  D GW   E E    RG FP ++ ++L  D
Sbjct: 256 IVTLINKDCIDVGW--WEGELNGRRGVFPDNFVKLLPPD 292


>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
           sapiens]
          Length = 665

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 8/99 (8%)

Query: 341 LPVRKSVTPKNSYATTENKTLPRSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGD 400
           LPV K++  K    T      P SS          +   K IF + A  N   L+ KEGD
Sbjct: 238 LPVEKTIGKKLPATTAT----PDSSKTEMDSRTKSKDYCKVIFPYEA-QNDDELTIKEGD 292

Query: 401 LITLLVPEARD-GWHYGESEKTKMRGWFPFSYTRVLDSD 438
           ++TL+  +  D GW   E E    RG FP ++ ++L  D
Sbjct: 293 IVTLINKDCIDVGW--WEGELNGRRGVFPDNFVKLLPPD 329


>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
          Length = 749

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 13/134 (9%)

Query: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKN-SYATTENKTLP--- 362
           GED     D +A + K++   +  + L ++        +   PKN S   T + ++    
Sbjct: 414 GED-----DLEALKAKNIKQTELVADLREAILRVARHFQCTDPKNCSVELTPDYSMESHQ 468

Query: 363 RSSSMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTK 422
           R         R+ R R KA+      D+  L  F++ D+IT++  +    W     E   
Sbjct: 469 RDHENYVACSRSHRRRAKALLDFERHDDDEL-GFRKNDIITIVSQKDEHCW---VGELNG 524

Query: 423 MRGWFPFSYTRVLD 436
           +RGWFP  +  VLD
Sbjct: 525 LRGWFPAKFVEVLD 538


>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
          Length = 1173

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 59/244 (24%), Positives = 106/244 (43%), Gaps = 37/244 (15%)

Query: 19  TIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQ 78
           TIME+F   L       K+ E+ +A      +G  D    + ++  E Q  +   D +  
Sbjct: 654 TIMERFQMEL-------KDVERKIAQQAAKLQG-IDLDRTVQQVNQEKQEKQHKLDTVSS 705

Query: 79  MAEVHRQ-IQNQLEEM--LKSFHNELLT---------QLEQKVELDSRYLSAALKKYQTE 126
             E++R+ IQ+Q E++  LKS  NEL +         Q  Q++E  +  LS  ++    E
Sbjct: 706 KIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYRE 765

Query: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQ-----YIDAISNKQG---ELENY 178
            +   + +   +  L+K +++ +   N +  S+K  Q       + + N  G   ++ENY
Sbjct: 766 IKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENY 825

Query: 179 VSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPE 238
           + DG      ++        E    +A+ S     K KE + + + L +Q   D  KI E
Sbjct: 826 IQDGKDDYKKQKE------TELNKVIAQLSEC--EKHKEKINEDMRLMRQD-IDTQKIQE 876

Query: 239 RAVQ 242
           R +Q
Sbjct: 877 RWLQ 880


>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
          Length = 1312

 Score = 38.5 bits (88), Expect = 0.015
 Identities = 59/244 (24%), Positives = 106/244 (43%), Gaps = 37/244 (15%)

Query: 19   TIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQ 78
            TIME+F   L       K+ E+ +A      +G  D    + ++  E Q  +   D +  
Sbjct: 793  TIMERFQMEL-------KDVERKIAQQAAKLQG-IDLDRTVQQVNQEKQEKQHKLDTVSS 844

Query: 79   MAEVHRQ-IQNQLEEM--LKSFHNELLT---------QLEQKVELDSRYLSAALKKYQTE 126
              E++R+ IQ+Q E++  LKS  NEL +         Q  Q++E  +  LS  ++    E
Sbjct: 845  KIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTNLQRRQQLEEQTVELSTEVQSLYRE 904

Query: 127  QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQ-----YIDAISNKQG---ELENY 178
             +   + +   +  L+K +++ +   N +  S+K  Q       + + N  G   ++ENY
Sbjct: 905  IKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIAQDKLNDIKEKVKNIHGYMKDIENY 964

Query: 179  VSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPE 238
            + DG      ++        E    +A+ S     K KE + + + L +Q   D  KI E
Sbjct: 965  IQDGKDDYKKQKE------TELNKVIAQLSEC--EKHKEKINEDMRLMRQD-IDTQKIQE 1015

Query: 239  RAVQ 242
            R +Q
Sbjct: 1016 RWLQ 1019


>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
           sapiens]
          Length = 1323

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 51/217 (23%), Positives = 95/217 (43%), Gaps = 30/217 (13%)

Query: 85  QIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKL 144
           ++Q   +E  ++   + L Q +++ E   R L A  +K   EQ+ +   L++ Q   K+L
Sbjct: 356 RLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKEL 415

Query: 145 RKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAV 204
           RK  Q  +  +++ +++++  +     + E E      YK    EE+R+     E+    
Sbjct: 416 RK--QQEREQRRHYEEQMRREEERRRAEHEQE------YKRKQLEEQRQ----AERLQRQ 463

Query: 205 AKNSAAY-----HSKGKELLAQKLPLWQ-QACADPSKIPERAVQLMQQVASNGATLPSAL 258
            K    Y     H + ++   +K PL+  +    PS+ P  A ++ ++   N  + P A+
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSP-AM 522

Query: 259 SASKSNLVISDP----------IPGAKPLPVPPELAP 285
               +N  ISDP          I G +P   PP L P
Sbjct: 523 PHKVANR-ISDPNLPPRSESFSISGVQPARTPPMLRP 558


>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
           sapiens]
          Length = 1331

 Score = 37.7 bits (86), Expect = 0.026
 Identities = 51/217 (23%), Positives = 95/217 (43%), Gaps = 30/217 (13%)

Query: 85  QIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKL 144
           ++Q   +E  ++   + L Q +++ E   R L A  +K   EQ+ +   L++ Q   K+L
Sbjct: 356 RLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKEL 415

Query: 145 RKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAV 204
           RK  Q  +  +++ +++++  +     + E E      YK    EE+R+     E+    
Sbjct: 416 RK--QQEREQRRHYEEQMRREEERRRAEHEQE------YKRKQLEEQRQ----AERLQRQ 463

Query: 205 AKNSAAY-----HSKGKELLAQKLPLWQ-QACADPSKIPERAVQLMQQVASNGATLPSAL 258
            K    Y     H + ++   +K PL+  +    PS+ P  A ++ ++   N  + P A+
Sbjct: 464 LKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEVEERSRLNRQSSP-AM 522

Query: 259 SASKSNLVISDP----------IPGAKPLPVPPELAP 285
               +N  ISDP          I G +P   PP L P
Sbjct: 523 PHKVANR-ISDPNLPPRSESFSISGVQPARTPPMLRP 558


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 37.4 bits (85), Expect = 0.033
 Identities = 48/218 (22%), Positives = 90/218 (41%), Gaps = 21/218 (9%)

Query: 61   ELASESQGSKELGDVLFQMAEVHRQIQN---------QLEEMLKSFHNELLTQLEQKVEL 111
            E AS ++  K+  D+  ++ E+  +++          +L +  ++   +L   LE+    
Sbjct: 1128 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQ 1187

Query: 112  DSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNK 171
                ++A  KK+       G+ +D  Q   +KL K+    K     +D      +AIS  
Sbjct: 1188 HEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELK---METDDLSSNAEAISKA 1244

Query: 172  QG-------ELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLP 224
            +G        LE+ VS+  KT   E++R    L  ++  +   +  Y  +  E  A    
Sbjct: 1245 KGNLEKMCRSLEDQVSE-LKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQ 1303

Query: 225  LWQQACADPSKIPERAVQLMQQVASNGATLPSALSASK 262
            L +   A   +I E   QL ++  +  A L  AL +S+
Sbjct: 1304 LSRSKQASTQQIEELKHQLEEETKAKNA-LAHALQSSR 1340



 Score = 29.3 bits (64), Expect = 9.1
 Identities = 24/112 (21%), Positives = 54/112 (48%), Gaps = 7/112 (6%)

Query: 76  LFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKK------YQTEQRS 129
           L + AE  +++    EE  K+  +EL     ++ EL+ + ++   +K       Q+E  S
Sbjct: 842 LLKSAETEKEMATMKEEFQKT-KDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADS 900

Query: 130 KGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSD 181
             DA ++C+  +K   +     K   + +++E +    ++ K+ +LE+  S+
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSE 952


>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
          Length = 2025

 Score = 37.4 bits (85), Expect = 0.033
 Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 28/128 (21%)

Query: 83   HRQIQNQLEEMLKSFHNELLTQLEQ------------------KVELD--SRYLSAALKK 122
            H+ +Q+QL+E+ +++    L  LE+                  K ELD   + L   +KK
Sbjct: 1499 HQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKK 1558

Query: 123  YQTEQRSKGDALDKCQAELKKL--------RKKSQGSKNPQKYSDKELQYIDAISNKQGE 174
            +Q E++   + L   + ++KK+        +K     K  + + D+ L+  + ++N++ +
Sbjct: 1559 WQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMK 1618

Query: 175  LENYVSDG 182
            +E Y+  G
Sbjct: 1619 IEEYIKKG 1626


>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
          Length = 2025

 Score = 37.4 bits (85), Expect = 0.033
 Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 28/128 (21%)

Query: 83   HRQIQNQLEEMLKSFHNELLTQLEQ------------------KVELD--SRYLSAALKK 122
            H+ +Q+QL+E+ +++    L  LE+                  K ELD   + L   +KK
Sbjct: 1499 HQVLQDQLQEVYENYEQIKLKGLEETRDLEEKLKRHLEENKISKTELDWFLQDLEREIKK 1558

Query: 123  YQTEQRSKGDALDKCQAELKKL--------RKKSQGSKNPQKYSDKELQYIDAISNKQGE 174
            +Q E++   + L   + ++KK+        +K     K  + + D+ L+  + ++N++ +
Sbjct: 1559 WQQEKKEIQERLKSLKKKIKKVSNASEMYTQKNDGKEKEHELHLDQSLEISNTLTNEKMK 1618

Query: 175  LENYVSDG 182
            +E Y+  G
Sbjct: 1619 IEEYIKKG 1626


>gi|7108367 vav 1 guanine nucleotide exchange factor [Homo sapiens]
          Length = 845

 Score = 37.0 bits (84), Expect = 0.044
 Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 3/52 (5%)

Query: 380 KAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFPFSY 431
           KA +   A D S L S KEGD+I +L  + + GW  GE       GWFP +Y
Sbjct: 788 KARYDFCARDRSEL-SLKEGDIIKILNKKGQQGWWRGEIYGRV--GWFPANY 836



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 13/35 (37%), Positives = 16/35 (45%)

Query: 394 LSFKEGDLITLLVPEARDGWHYGESEKTKMRGWFP 428
           L    GD++ L   EA   W  G +  T   GWFP
Sbjct: 617 LRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFP 651


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
           plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score = 37.0 bits (84), Expect = 0.044
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 8/67 (11%)

Query: 277 LPVPPELAPFVGRMSAQESTPIMNGVTGPDGEDYSPWADRKAAQPKSLSPPQSQSKLSDS 336
           LP PP     +        T +  G + P+G  Y        A P+  SP QS S+L+ S
Sbjct: 259 LPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATY--------AAPRGSSPKQSPSRLAKS 310

Query: 337 YSNTLPV 343
           YS + P+
Sbjct: 311 YSTSSPI 317


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,027,609
Number of Sequences: 37866
Number of extensions: 872537
Number of successful extensions: 4036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 273
Number of HSP's that attempted gapping in prelim test: 3811
Number of HSP's gapped (non-prelim): 500
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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