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Search of human proteins with 54112385
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54112385 four and a half LIM domains 3 [Homo sapiens]
(280 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 634 0.0
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 379 e-105
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 379 e-105
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 379 e-105
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 379 e-105
gi|30410801 activator of cAMP-responsive element modulator (CREM... 336 1e-92
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 297 6e-81
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 297 6e-81
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 297 6e-81
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 297 6e-81
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 297 6e-81
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 259 2e-69
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens] 182 2e-46
gi|221316659 leupaxin isoform 1 [Homo sapiens] 120 2e-27
gi|4758670 leupaxin isoform 2 [Homo sapiens] 120 2e-27
gi|109638745 transforming growth factor beta 1 induced transcrip... 120 2e-27
gi|21361591 transforming growth factor beta 1 induced transcript... 120 2e-27
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 119 2e-27
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 119 2e-27
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 119 3e-27
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 119 3e-27
gi|170932518 paxillin isoform 3 [Homo sapiens] 119 4e-27
gi|170932516 paxillin isoform 2 [Homo sapiens] 119 4e-27
gi|170932514 paxillin isoform 1 [Homo sapiens] 119 4e-27
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 117 1e-26
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 115 3e-26
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 115 3e-26
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 115 6e-26
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 114 1e-25
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 113 2e-25
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 634 bits (1635), Expect = 0.0
Identities = 280/280 (100%), Positives = 280/280 (100%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH
Sbjct: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ
Sbjct: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE
Sbjct: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
Query: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP 280
DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP
Sbjct: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP 280
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 379 bits (974), Expect = e-105
Identities = 149/277 (53%), Positives = 208/277 (75%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC CNESL+G+KYI + PYCV C++ FANTC EC + IG D ++L Y+DRH
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+HE CF C +C+ SL D+PF ++ +LLC DCY + +SS+C C +T+MPG+RK+EY G
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
+WHE CF+C C+QP+G++SF+P ++CVPCYE + A +C +C K +T GGVTYR+QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
WH+EC VCT C+ L+GQ+FT+RD+ YC+ CF +L+A KC+ C PI GLGG KY+SFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
+R WH++CF+C +CS SLVG+GF+ + D +LC C +
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 379 bits (974), Expect = e-105
Identities = 149/277 (53%), Positives = 208/277 (75%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC CNESL+G+KYI + PYCV C++ FANTC EC + IG D ++L Y+DRH
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+HE CF C +C+ SL D+PF ++ +LLC DCY + +SS+C C +T+MPG+RK+EY G
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
+WHE CF+C C+QP+G++SF+P ++CVPCYE + A +C +C K +T GGVTYR+QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
WH+EC VCT C+ L+GQ+FT+RD+ YC+ CF +L+A KC+ C PI GLGG KY+SFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
+R WH++CF+C +CS SLVG+GF+ + D +LC C +
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 379 bits (974), Expect = e-105
Identities = 149/277 (53%), Positives = 208/277 (75%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC CNESL+G+KYI + PYCV C++ FANTC EC + IG D ++L Y+DRH
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+HE CF C +C+ SL D+PF ++ +LLC DCY + +SS+C C +T+MPG+RK+EY G
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
+WHE CF+C C+QP+G++SF+P ++CVPCYE + A +C +C K +T GGVTYR+QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
WH+EC VCT C+ L+GQ+FT+RD+ YC+ CF +L+A KC+ C PI GLGG KY+SFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
+R WH++CF+C +CS SLVG+GF+ + D +LC C +
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 379 bits (974), Expect = e-105
Identities = 149/277 (53%), Positives = 208/277 (75%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC CNESL+G+KYI + PYCV C++ FANTC EC + IG D ++L Y+DRH
Sbjct: 1 MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+HE CF C +C+ SL D+PF ++ +LLC DCY + +SS+C C +T+MPG+RK+EY G
Sbjct: 61 WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
+WHE CF+C C+QP+G++SF+P ++CVPCYE + A +C +C K +T GGVTYR+QP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
WH+EC VCT C+ L+GQ+FT+RD+ YC+ CF +L+A KC+ C PI GLGG KY+SFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
Query: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
+R WH++CF+C +CS SLVG+GF+ + D +LC C +
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
>gi|30410801 activator of cAMP-responsive element modulator (CREM)
in testis [Homo sapiens]
Length = 284
Score = 336 bits (862), Expect = 1e-92
Identities = 131/271 (48%), Positives = 184/271 (67%)
Query: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
F C C SL G+KY+ D PYCV CYD F+N C EC++ I DS++L Y+DRH+HEG
Sbjct: 6 FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65
Query: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHE 124
CF+C +C SL ++PF +D LLC +CY + SS+C C T+MPGSRK+E+ G WHE
Sbjct: 66 CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHE 125
Query: 125 HCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRE 184
CF+C C QP+G++ + + +YCVPC+E +FA C C K +T GG+T+ DQ WH+E
Sbjct: 126 TCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKE 185
Query: 185 CLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHW 244
C +C+GC+ L +QF SRD+ P+C+ C+ L+A KC +C +PI GL G K++ F+D W
Sbjct: 186 CFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQW 245
Query: 245 HHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
H CF+C +CS SLVG+GF+ ++ CQ C
Sbjct: 246 HSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
Score = 69.3 bits (168), Expect = 3e-12
Identities = 28/92 (30%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIG--HDSRELFYEDRH 60
E F C+ C + L +++ D P+C+ CY++ +AN C C + I ++ + ++D
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDC 92
+H CF C +C SL + F Q+ E+ C C
Sbjct: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
Score = 30.4 bits (67), Expect = 1.8
Identities = 11/30 (36%), Positives = 18/30 (60%)
Query: 2 SESFDCAKCNESLYGRKYIQTDSGPYCVPC 31
SE F+C KC+ SL G+ ++ + +C C
Sbjct: 247 SECFNCGKCSVSLVGKGFLTQNKEIFCQKC 276
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 297 bits (761), Expect = 6e-81
Identities = 123/278 (44%), Positives = 175/278 (62%), Gaps = 1/278 (0%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K +T GG+TY+DQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLG-GGKYVSF 239
WH +C VC C LAGQ+FT+ ++ YCV C+ A KC+ CK PI G G G V++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 240 EDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
E + WH CF C +CS +L + FV +QV C C++
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 297 bits (761), Expect = 6e-81
Identities = 123/278 (44%), Positives = 175/278 (62%), Gaps = 1/278 (0%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K +T GG+TY+DQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLG-GGKYVSF 239
WH +C VC C LAGQ+FT+ ++ YCV C+ A KC+ CK PI G G G V++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 240 EDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
E + WH CF C +CS +L + FV +QV C C++
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 297 bits (761), Expect = 6e-81
Identities = 123/278 (44%), Positives = 175/278 (62%), Gaps = 1/278 (0%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 30 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 89
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 90 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K +T GG+TY+DQP
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 209
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLG-GGKYVSF 239
WH +C VC C LAGQ+FT+ ++ YCV C+ A KC+ CK PI G G G V++
Sbjct: 210 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 269
Query: 240 EDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
E + WH CF C +CS +L + FV +QV C C++
Sbjct: 270 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 307
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 297 bits (761), Expect = 6e-81
Identities = 123/278 (44%), Positives = 175/278 (62%), Gaps = 1/278 (0%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 17 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 77 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K +T GG+TY+DQP
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLG-GGKYVSF 239
WH +C VC C LAGQ+FT+ ++ YCV C+ A KC+ CK PI G G G V++
Sbjct: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256
Query: 240 EDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
E + WH CF C +CS +L + FV +QV C C++
Sbjct: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 294
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 297 bits (761), Expect = 6e-81
Identities = 123/278 (44%), Positives = 175/278 (62%), Gaps = 1/278 (0%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K +T GG+TY+DQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLG-GGKYVSF 239
WH +C VC C LAGQ+FT+ ++ YCV C+ A KC+ CK PI G G G V++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240
Query: 240 EDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
E + WH CF C +CS +L + FV +QV C C++
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 259 bits (662), Expect = 2e-69
Identities = 105/230 (45%), Positives = 148/230 (64%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K +T GG+TY+DQP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVG 230
WH +C VC C LAGQ+FT+ ++ YCV C+ A KC+ CK PI G
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230
Score = 140 bits (353), Expect = 1e-33
Identities = 64/212 (30%), Positives = 99/212 (46%), Gaps = 6/212 (2%)
Query: 66 FRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEH 125
F C C+ L + + +D C C+ ++ C C + + S+++ Y + WH+
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 126 CFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQG--GVTYRDQPWHR 183
CF C+ C PL + +FV C C + +P+C C K + G V Y+ WH+
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
Query: 184 ECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRH 243
+C C+ C+ + F + ED YCV C FA C C + I G ++++D+
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180
Query: 244 WHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
WH +CF C CS L GQ F DQ C C
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDC 212
Score = 100 bits (248), Expect = 2e-21
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 127 FLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG--VTYRDQPWHRE 184
F C C PL + +V G H C+ C++ A C C K + V Y+++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 185 CLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHW 244
C C C PLA + F ++D C C +PKC C + IV G + V ++ W
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA--GDQNVEYKGTVW 122
Query: 245 HHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
H +CF+C+ C + F P G+ C C +
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
Length = 194
Score = 182 bits (463), Expect = 2e-46
Identities = 77/182 (42%), Positives = 113/182 (62%), Gaps = 2/182 (1%)
Query: 1 MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60
M+E FDC C + L G+KY+Q D C+ C+D ANTC EC++ IG DS+E+ Y++R
Sbjct: 1 MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H+ CFRC +C LA+E F +D+++LCN C S +C C + ++ G + +EY G
Sbjct: 61 WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTY--RD 178
WH+ CF CS C+Q +G+ SF P YCV C+E KFA C +C+K L + V + +D
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPVWWPMKD 180
Query: 179 QP 180
P
Sbjct: 181 NP 182
Score = 106 bits (265), Expect = 2e-23
Identities = 47/166 (28%), Positives = 77/166 (46%), Gaps = 2/166 (1%)
Query: 66 FRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEH 125
F C C+ L + + +D C C+ ++ C C + + S+++ Y + WH+
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 126 CFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQG--GVTYRDQPWHR 183
CF C+ C PL + +FV C C + +P+C C K + G V Y+ WH+
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124
Query: 184 ECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIV 229
+C C+ C+ + F + ED YCV C FA C C + +V
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLV 170
Score = 100 bits (248), Expect = 2e-21
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 127 FLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG--VTYRDQPWHRE 184
F C C PL + +V G H C+ C++ A C C K + V Y+++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 185 CLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHW 244
C C C PLA + F ++D C C +PKC C + IV G + V ++ W
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVA--GDQNVEYKGTVW 122
Query: 245 HHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277
H +CF+C+ C + F P G+ C C +
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHE 155
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 120 bits (300), Expect = 2e-27
Identities = 62/189 (32%), Positives = 88/189 (46%), Gaps = 18/189 (9%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C++C + + + + GQ+WH F+C+ C++ +GS F G YC Y F+P
Sbjct: 157 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
RCA C+ + +T +Q WH E C+ C + F +D+ PYC F +F+PK
Sbjct: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 274
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSL-VGQGFVPDGDQ---------- 269
C C RP++ Y+S D WH CF C C TS G F DG
Sbjct: 275 CGGCNRPVL----ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRR 330
Query: 270 -VLCQGCSQ 277
LC GC Q
Sbjct: 331 GTLCHGCGQ 339
Score = 113 bits (283), Expect = 2e-25
Identities = 65/236 (27%), Positives = 98/236 (41%), Gaps = 8/236 (3%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
CA CQ+ I + + + +H F C C+ + PF + C + Y FS
Sbjct: 157 CASCQKPIA--GKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
+C+ C ++ + L QTWH F CS C + G+ F YC + F+
Sbjct: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
Query: 160 PRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAP 219
P+C C++ + + ++ D WH EC VC C T + F D P+C +
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
Query: 220 KCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
C C +PI G+ +S +H F CA C T L F D+ CQ C
Sbjct: 333 LCHGCGQPIT----GRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 384
Score = 94.7 bits (234), Expect = 8e-20
Identities = 56/215 (26%), Positives = 85/215 (39%), Gaps = 4/215 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C C E + + + YC Y F+ CA C I + L ++ +H
Sbjct: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 236
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
F C C E F +D + C + + FS +C C V+ L W
Sbjct: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 294
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182
H CF+C C + SF G +C Y ++ C C + +T ++ +H
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354
Query: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
E VC C T L+ F +++ YC CF +LF
Sbjct: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 120 bits (300), Expect = 2e-27
Identities = 62/189 (32%), Positives = 88/189 (46%), Gaps = 18/189 (9%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C++C + + + + GQ+WH F+C+ C++ +GS F G YC Y F+P
Sbjct: 152 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
RCA C+ + +T +Q WH E C+ C + F +D+ PYC F +F+PK
Sbjct: 210 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 269
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSL-VGQGFVPDGDQ---------- 269
C C RP++ Y+S D WH CF C C TS G F DG
Sbjct: 270 CGGCNRPVL----ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRR 325
Query: 270 -VLCQGCSQ 277
LC GC Q
Sbjct: 326 GTLCHGCGQ 334
Score = 113 bits (283), Expect = 2e-25
Identities = 65/236 (27%), Positives = 98/236 (41%), Gaps = 8/236 (3%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
CA CQ+ I + + + +H F C C+ + PF + C + Y FS
Sbjct: 152 CASCQKPIA--GKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
+C+ C ++ + L QTWH F CS C + G+ F YC + F+
Sbjct: 210 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267
Query: 160 PRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAP 219
P+C C++ + + ++ D WH EC VC C T + F D P+C +
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327
Query: 220 KCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
C C +PI G+ +S +H F CA C T L F D+ CQ C
Sbjct: 328 LCHGCGQPIT----GRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 379
Score = 94.7 bits (234), Expect = 8e-20
Identities = 56/215 (26%), Positives = 85/215 (39%), Gaps = 4/215 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C C E + + + YC Y F+ CA C I + L ++ +H
Sbjct: 174 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPIL--DKVLTAMNQTWH 231
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
F C C E F +D + C + + FS +C C V+ L W
Sbjct: 232 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVL--ENYLSAMDTVW 289
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182
H CF+C C + SF G +C Y ++ C C + +T ++ +H
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 349
Query: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
E VC C T L+ F +++ YC CF +LF
Sbjct: 350 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 120 bits (300), Expect = 2e-27
Identities = 57/173 (32%), Positives = 80/173 (46%), Gaps = 6/173 (3%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C +C + + + + G+ WH F+C GC LG SF GA +C CY +F+P
Sbjct: 228 CGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
RC C++ + VT WH E C C P + F R+ PYC F +LFAP+
Sbjct: 286 RCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPR 345
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C+ PI+ Y+S WH +CF C C G F + LC+
Sbjct: 346 CQGCQGPIL----DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCE 394
Score = 110 bits (276), Expect = 1e-24
Identities = 61/217 (28%), Positives = 87/217 (40%), Gaps = 6/217 (2%)
Query: 59 RHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYG 118
R +H F C C +L F +D C +CY FS +C C + + + +
Sbjct: 245 RAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTAL 302
Query: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178
G WH F C C +P G F +G YC + FAPRC C + ++
Sbjct: 303 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALS 362
Query: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238
WH +C VC C P +G F + P C F C++C P+ G+ VS
Sbjct: 363 ALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVT----GRCVS 418
Query: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
R +H + F+C C L F + CQ C
Sbjct: 419 ALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455
Score = 109 bits (273), Expect = 2e-24
Identities = 60/215 (27%), Positives = 87/215 (40%), Gaps = 4/215 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C C+ +L G + + D P+C CY F+ C C Q I H + + H+H
Sbjct: 250 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 307
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
F C C DE F ++ C + F+ +C C ++ + W
Sbjct: 308 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 365
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182
H CF+C C P SF +G C + + CA C +T V+ + +H
Sbjct: 366 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 425
Query: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
+ CT C PL F R PYC CF +LF
Sbjct: 426 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460
Score = 40.0 bits (92), Expect = 0.002
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
C SC +PI G + V+ R WH F C CST+L G F C C
Sbjct: 228 CGSCNKPIAG----QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 278
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 120 bits (300), Expect = 2e-27
Identities = 57/173 (32%), Positives = 80/173 (46%), Gaps = 6/173 (3%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C +C + + + + G+ WH F+C GC LG SF GA +C CY +F+P
Sbjct: 211 CGSCNKPI--AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
RC C++ + VT WH E C C P + F R+ PYC F +LFAP+
Sbjct: 269 RCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPR 328
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C+ PI+ Y+S WH +CF C C G F + LC+
Sbjct: 329 CQGCQGPIL----DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCE 377
Score = 110 bits (276), Expect = 1e-24
Identities = 61/217 (28%), Positives = 87/217 (40%), Gaps = 6/217 (2%)
Query: 59 RHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYG 118
R +H F C C +L F +D C +CY FS +C C + + + +
Sbjct: 228 RAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIR--HKMVTAL 285
Query: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178
G WH F C C +P G F +G YC + FAPRC C + ++
Sbjct: 286 GTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNYISALS 345
Query: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238
WH +C VC C P +G F + P C F C++C P+ G+ VS
Sbjct: 346 ALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVT----GRCVS 401
Query: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
R +H + F+C C L F + CQ C
Sbjct: 402 ALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
Score = 109 bits (273), Expect = 2e-24
Identities = 60/215 (27%), Positives = 87/215 (40%), Gaps = 4/215 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C C+ +L G + + D P+C CY F+ C C Q I H + + H+H
Sbjct: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 290
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
F C C DE F ++ C + F+ +C C ++ + W
Sbjct: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALW 348
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182
H CF+C C P SF +G C + + CA C +T V+ + +H
Sbjct: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408
Query: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
+ CT C PL F R PYC CF +LF
Sbjct: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
Score = 40.0 bits (92), Expect = 0.002
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
C SC +PI G + V+ R WH F C CST+L G F C C
Sbjct: 211 CGSCNKPIAG----QVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 261
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 119 bits (299), Expect = 2e-27
Identities = 56/155 (36%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
Query: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178
G++WH F C+ C+ + FV +KGA YC CYE FAP C RC + + ++
Sbjct: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386
Query: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238
Q WH C VC C P+ F D +PYC + LF C C+ PI G ++
Sbjct: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 444
Query: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
WH CF C+ C SL GQ F D+ LC+
Sbjct: 445 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 479
Score = 89.0 bits (219), Expect = 4e-18
Identities = 45/149 (30%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQ-LIGHDSRELFYEDRHF 61
E F+CA C ++ +++ YC CY+ FA C CQ+ ++G L + +
Sbjct: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISAL---KQTW 389
Query: 62 HEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQT 121
H CF C C + + + F +D E C Y + F + C C + G LE G T
Sbjct: 390 HVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYT 449
Query: 122 WHEHCFLCSGCEQPLGSRSFVPDKGAHYC 150
WH+ CF+CS C + L ++F K C
Sbjct: 450 WHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
Score = 88.2 bits (217), Expect = 7e-18
Identities = 50/172 (29%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
CA C Q+I L + +H F C C+ ++A F + L C CY F+
Sbjct: 311 CAHCNQVIRGPF--LVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
+C C ++ + QTWH CF+C C +P+ + F + G YC Y F
Sbjct: 369 ECGRCQRKIL--GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 426
Query: 160 PRCARCSKTLTQGGVTYR--DQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209
C C + G + WH C VC+ C L GQ F S+ + P C
Sbjct: 427 TICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478
Score = 66.6 bits (161), Expect = 2e-11
Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 157 KFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGEL 216
K P CA C++ + + + WH E C C+ +A F YC C+ +
Sbjct: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 365
Query: 217 FAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGF-VPDGDQ------ 269
FAP+C C+R I+ G+ +S + WH +CF C C + F + DG+
Sbjct: 366 FAPECGRCQRKIL----GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY 421
Query: 270 -----VLCQGC 275
+C GC
Sbjct: 422 YALFGTICHGC 432
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 119 bits (299), Expect = 2e-27
Identities = 56/155 (36%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
Query: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178
G++WH F C+ C+ + FV +KGA YC CYE FAP C RC + + ++
Sbjct: 436 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 495
Query: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238
Q WH C VC C P+ F D +PYC + LF C C+ PI G ++
Sbjct: 496 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 553
Query: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
WH CF C+ C SL GQ F D+ LC+
Sbjct: 554 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLCK 588
Score = 89.0 bits (219), Expect = 4e-18
Identities = 45/149 (30%), Positives = 69/149 (46%), Gaps = 4/149 (2%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQ-LIGHDSRELFYEDRHF 61
E F+CA C ++ +++ YC CY+ FA C CQ+ ++G L + +
Sbjct: 442 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISAL---KQTW 498
Query: 62 HEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQT 121
H CF C C + + + F +D E C Y + F + C C + G LE G T
Sbjct: 499 HVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYT 558
Query: 122 WHEHCFLCSGCEQPLGSRSFVPDKGAHYC 150
WH+ CF+CS C + L ++F K C
Sbjct: 559 WHDTCFVCSVCCESLEGQTFFSKKDKPLC 587
Score = 88.2 bits (217), Expect = 7e-18
Identities = 50/172 (29%), Positives = 72/172 (41%), Gaps = 6/172 (3%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
CA C Q+I L + +H F C C+ ++A F + L C CY F+
Sbjct: 420 CAHCNQVIRGPF--LVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
+C C ++ + QTWH CF+C C +P+ + F + G YC Y F
Sbjct: 478 ECGRCQRKIL--GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFG 535
Query: 160 PRCARCSKTLTQGGVTYR--DQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209
C C + G + WH C VC+ C L GQ F S+ + P C
Sbjct: 536 TICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 587
Score = 66.6 bits (161), Expect = 2e-11
Identities = 36/131 (27%), Positives = 56/131 (42%), Gaps = 16/131 (12%)
Query: 157 KFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGEL 216
K P CA C++ + + + WH E C C+ +A F YC C+ +
Sbjct: 415 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKF 474
Query: 217 FAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGF-VPDGDQ------ 269
FAP+C C+R I+ G+ +S + WH +CF C C + F + DG+
Sbjct: 475 FAPECGRCQRKIL----GEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDY 530
Query: 270 -----VLCQGC 275
+C GC
Sbjct: 531 YALFGTICHGC 541
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 119 bits (298), Expect = 3e-27
Identities = 55/155 (35%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
Query: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178
G++WH F C+ C+ L FV ++ YC CYE FAP CA+C+ + +
Sbjct: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
Query: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238
Q WH C VC C+ P F D +PYC + LF+ KC C P+ G K++
Sbjct: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 574
Query: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
WH CF CA C +L GQ F D+ LC+
Sbjct: 575 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
Score = 100 bits (250), Expect = 1e-21
Identities = 53/172 (30%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
C C +I L R +H F C C+ SLAD F + + + C CY F+
Sbjct: 441 CGHCNNVIRGPF--LVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
C+ C +M + QTWH CF+C+ C++P G+ F + G YC Y N F+
Sbjct: 499 LCAKCNTKIM--GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 556
Query: 160 PRCARCSKTLTQGG--VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209
+C C + G + WH C +C C L GQ F S+ + P C
Sbjct: 557 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 94.7 bits (234), Expect = 8e-20
Identities = 46/148 (31%), Positives = 68/148 (45%), Gaps = 2/148 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F CA C SL +++ + YC CY+ FA CA+C I + + +H
Sbjct: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQT--WH 520
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
CF C C++ + F +D E C Y + FS++C C V G + +E G TW
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYC 150
H+ CF+C+ C L + F K C
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 65.5 bits (158), Expect = 5e-11
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 4/114 (3%)
Query: 160 PRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAP 219
P C C+ + + + WH E C C+T LA F + YC C+ + FAP
Sbjct: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
Query: 220 KCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C+ C I+ G+ + + WH CF CA C F + + C+
Sbjct: 499 LCAKCNTKIM----GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 548
Score = 40.0 bits (92), Expect = 0.002
Identities = 35/125 (28%), Positives = 46/125 (36%), Gaps = 22/125 (17%)
Query: 154 YENKFAPRCARCS---KTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCV 210
+ KFAP + S +TL +GG Y G Q P + R E
Sbjct: 386 FSQKFAPGKSTTSISKQTLPRGGPAYTP----------AGPQVPPLARGTVQRAE----- 430
Query: 211 ACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQV 270
P C C I G ++ R WH F+CA C TSL FV + + V
Sbjct: 431 RFPASSRTPLCGHCNNVI----RGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNV 486
Query: 271 LCQGC 275
C+ C
Sbjct: 487 YCERC 491
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 119 bits (298), Expect = 3e-27
Identities = 55/155 (35%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
Query: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178
G++WH F C+ C+ L FV ++ YC CYE FAP CA+C+ + +
Sbjct: 567 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 626
Query: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238
Q WH C VC C+ P F D +PYC + LF+ KC C P+ G K++
Sbjct: 627 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 684
Query: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
WH CF CA C +L GQ F D+ LC+
Sbjct: 685 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719
Score = 100 bits (250), Expect = 1e-21
Identities = 53/172 (30%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
C C +I L R +H F C C+ SLAD F + + + C CY F+
Sbjct: 551 CGHCNNVIRGPF--LVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 608
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
C+ C +M + QTWH CF+C+ C++P G+ F + G YC Y N F+
Sbjct: 609 LCAKCNTKIM--GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 666
Query: 160 PRCARCSKTLTQGG--VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209
+C C + G + WH C +C C L GQ F S+ + P C
Sbjct: 667 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 94.7 bits (234), Expect = 8e-20
Identities = 46/148 (31%), Positives = 68/148 (45%), Gaps = 2/148 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F CA C SL +++ + YC CY+ FA CA+C I + + +H
Sbjct: 573 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQT--WH 630
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
CF C C++ + F +D E C Y + FS++C C V G + +E G TW
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYC 150
H+ CF+C+ C L + F K C
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 65.5 bits (158), Expect = 5e-11
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 4/114 (3%)
Query: 160 PRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAP 219
P C C+ + + + WH E C C+T LA F + YC C+ + FAP
Sbjct: 549 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 608
Query: 220 KCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C+ C I+ G+ + + WH CF CA C F + + C+
Sbjct: 609 LCAKCNTKIM----GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 658
Score = 40.0 bits (92), Expect = 0.002
Identities = 35/125 (28%), Positives = 46/125 (36%), Gaps = 22/125 (17%)
Query: 154 YENKFAPRCARCS---KTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCV 210
+ KFAP + S +TL +GG Y G Q P + R E
Sbjct: 496 FSQKFAPGKSTTSISKQTLPRGGPAYTP----------AGPQVPPLARGTVQRAE----- 540
Query: 211 ACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQV 270
P C C I G ++ R WH F+CA C TSL FV + + V
Sbjct: 541 RFPASSRTPLCGHCNNVI----RGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNV 596
Query: 271 LCQGC 275
C+ C
Sbjct: 597 YCERC 601
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 119 bits (297), Expect = 4e-27
Identities = 62/215 (28%), Positives = 92/215 (42%), Gaps = 6/215 (2%)
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H F C CQ + F +D + C Y + FS +C C ++ + + +
Sbjct: 210 WHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDR 267
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
TWH F C+ C G F G YC Y + FAP+C C++ + + ++ +
Sbjct: 268 TWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTL 327
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
WH EC VC C TP F D PYC + E CS C++PI G+ ++
Sbjct: 328 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPIT----GRCITAM 383
Query: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
+ +H F CA C L F D+ CQ C
Sbjct: 384 AKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 418
Score = 115 bits (288), Expect = 4e-26
Identities = 57/173 (32%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C AC + + + + G+TWH F+C+ C++ +GSR+F G YC Y N F+P
Sbjct: 191 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
RC C+ + VT D+ WH E C C + F +D YC + ++FAPK
Sbjct: 249 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 308
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C R I+ Y+S + WH CF C C T V F Q C+
Sbjct: 309 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 357
Score = 112 bits (281), Expect = 3e-25
Identities = 62/215 (28%), Positives = 89/215 (41%), Gaps = 4/215 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C C E + R + + D PYC Y N F+ C C I + + DR +H
Sbjct: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 270
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
F C +C E F +D + C Y F+ +C C ++ + W
Sbjct: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 328
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182
H CF+C C P + SF G YC Y + C+ C K +T +T + +H
Sbjct: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388
Query: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
E VC C L F +++ PYC CF +LF
Sbjct: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
Score = 54.7 bits (130), Expect = 9e-08
Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 30/113 (26%)
Query: 187 VCTGCQTPLAGQ--------------------------QFTSRDEDPYCVACFGELFAPK 220
VC C+ P+AGQ F RD PYC + LF+P+
Sbjct: 190 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C PI+ K V+ DR WH F CA+C +GF + C+
Sbjct: 250 CYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCR 298
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 119 bits (297), Expect = 4e-27
Identities = 62/215 (28%), Positives = 92/215 (42%), Gaps = 6/215 (2%)
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H F C CQ + F +D + C Y + FS +C C ++ + + +
Sbjct: 343 WHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDR 400
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
TWH F C+ C G F G YC Y + FAP+C C++ + + ++ +
Sbjct: 401 TWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTL 460
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
WH EC VC C TP F D PYC + E CS C++PI G+ ++
Sbjct: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPIT----GRCITAM 516
Query: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
+ +H F CA C L F D+ CQ C
Sbjct: 517 AKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 551
Score = 115 bits (288), Expect = 4e-26
Identities = 57/173 (32%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C AC + + + + G+TWH F+C+ C++ +GSR+F G YC Y N F+P
Sbjct: 324 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
RC C+ + VT D+ WH E C C + F +D YC + ++FAPK
Sbjct: 382 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 441
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C R I+ Y+S + WH CF C C T V F Q C+
Sbjct: 442 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 490
Score = 112 bits (281), Expect = 3e-25
Identities = 62/215 (28%), Positives = 89/215 (41%), Gaps = 4/215 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C C E + R + + D PYC Y N F+ C C I + + DR +H
Sbjct: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 403
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
F C +C E F +D + C Y F+ +C C ++ + W
Sbjct: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 461
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182
H CF+C C P + SF G YC Y + C+ C K +T +T + +H
Sbjct: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521
Query: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
E VC C L F +++ PYC CF +LF
Sbjct: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
Score = 54.7 bits (130), Expect = 9e-08
Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 30/113 (26%)
Query: 187 VCTGCQTPLAGQ--------------------------QFTSRDEDPYCVACFGELFAPK 220
VC C+ P+AGQ F RD PYC + LF+P+
Sbjct: 323 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C PI+ K V+ DR WH F CA+C +GF + C+
Sbjct: 383 CYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCR 431
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 119 bits (297), Expect = 4e-27
Identities = 62/215 (28%), Positives = 92/215 (42%), Gaps = 6/215 (2%)
Query: 61 FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120
+H F C CQ + F +D + C Y + FS +C C ++ + + +
Sbjct: 377 WHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDR 434
Query: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180
TWH F C+ C G F G YC Y + FAP+C C++ + + ++ +
Sbjct: 435 TWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTL 494
Query: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240
WH EC VC C TP F D PYC + E CS C++PI G+ ++
Sbjct: 495 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPIT----GRCITAM 550
Query: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
+ +H F CA C L F D+ CQ C
Sbjct: 551 AKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNC 585
Score = 115 bits (288), Expect = 4e-26
Identities = 57/173 (32%), Positives = 81/173 (46%), Gaps = 6/173 (3%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C AC + + + + G+TWH F+C+ C++ +GSR+F G YC Y N F+P
Sbjct: 358 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 415
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
RC C+ + VT D+ WH E C C + F +D YC + ++FAPK
Sbjct: 416 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 475
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C R I+ Y+S + WH CF C C T V F Q C+
Sbjct: 476 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCE 524
Score = 112 bits (281), Expect = 3e-25
Identities = 62/215 (28%), Positives = 89/215 (41%), Gaps = 4/215 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C C E + R + + D PYC Y N F+ C C I + + DR +H
Sbjct: 380 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPIL--DKVVTALDRTWH 437
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
F C +C E F +D + C Y F+ +C C ++ + W
Sbjct: 438 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISALNTLW 495
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWH 182
H CF+C C P + SF G YC Y + C+ C K +T +T + +H
Sbjct: 496 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 555
Query: 183 RECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELF 217
E VC C L F +++ PYC CF +LF
Sbjct: 556 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
Score = 54.7 bits (130), Expect = 9e-08
Identities = 33/113 (29%), Positives = 44/113 (38%), Gaps = 30/113 (26%)
Query: 187 VCTGCQTPLAGQ--------------------------QFTSRDEDPYCVACFGELFAPK 220
VC C+ P+AGQ F RD PYC + LF+P+
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C PI+ K V+ DR WH F CA+C +GF + C+
Sbjct: 417 CYYCNGPIL----DKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCR 465
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 117 bits (293), Expect = 1e-26
Identities = 77/284 (27%), Positives = 119/284 (41%), Gaps = 15/284 (5%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
+ F CA+C + + + + YC + FA C +C + I R + + +H
Sbjct: 34 QCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWH 91
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQ-----CSACGETVMPGSRKLEY 117
CFRC CQ LAD F LC C+ + C C + + L +
Sbjct: 92 PECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIF 149
Query: 118 GGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYR 177
+H F C+ C + L + + KG YC+PC++ P C C + + V
Sbjct: 150 KNDPYHPDHFNCANCGKELTADAREL-KGELYCLPCHDKMGVPICGACRRPIEGRVVNAM 208
Query: 178 DQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYV 237
+ WH E VC C+ P G + R YC + +LF C C R I G V
Sbjct: 209 GKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVI----EGDVV 264
Query: 238 SFEDRHWHHNCFSCARCSTSL-VGQGFVPDGDQVLCQGCSQAGP 280
S ++ W NCF+C+ C+T L + FV + +C+ C + P
Sbjct: 265 SALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFP 308
Score = 110 bits (274), Expect = 2e-24
Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 12/227 (5%)
Query: 39 TCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFS 98
TC C+ + + +HE CF C +C + + F + C + F+
Sbjct: 9 TCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA 68
Query: 99 SQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKF 158
C CGE ++ R ++ +WH CF C C++ L FV + G H C PC+ +
Sbjct: 69 PCCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
Query: 159 APR-----CARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACF 213
A C +C + + + +++ P+H + C C L + E YC+ C
Sbjct: 127 ARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGE-LYCLPCH 185
Query: 214 GELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVG 260
++ P C +C+RPI G+ V+ + WH F CA+C +G
Sbjct: 186 DKMGVPICGACRRPI----EGRVVNAMGKQWHVEHFVCAKCEKPFLG 228
Score = 76.3 bits (186), Expect = 3e-14
Identities = 47/188 (25%), Positives = 75/188 (39%), Gaps = 20/188 (10%)
Query: 98 SSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENK 157
S+ C C P + + G+ +HE CF+C+ C Q F +G YC ++
Sbjct: 7 SATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQML 66
Query: 158 FAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVAC----- 212
FAP C +C + + + + WH EC C CQ LA F C C
Sbjct: 67 FAPCCHQCGEFIIGRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREK 126
Query: 213 ---FGELFAPKCSSC--KRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDG 267
G+ KC + ++P++ F++ +H + F+CA C L G
Sbjct: 127 ARGLGKYICQKCHAIIDEQPLI---------FKNDPYHPDHFNCANCGKELTADARELKG 177
Query: 268 DQVLCQGC 275
++ C C
Sbjct: 178 -ELYCLPC 184
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 115 bits (289), Expect = 3e-26
Identities = 56/173 (32%), Positives = 83/173 (47%), Gaps = 4/173 (2%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C C + + R L G +H F+CS C + L F +KGA +C PCY+ ++AP
Sbjct: 248 CHQCHKVIR--GRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
CA+C K +T + WH C C C+TP+ + F + PYC + ++F K
Sbjct: 306 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTK 365
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C I G +++ WH CF CA C +L G+ F D+ LC+
Sbjct: 366 CHGCDFKID--AGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 416
Score = 94.4 bits (233), Expect = 1e-19
Identities = 49/172 (28%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
C +C ++I R L +H F C +C + L + F + + C CY ++
Sbjct: 248 CHQCHKVIR--GRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
C+ C + + + TWH HCF C+ C+ P+ +R+F ++G YC YE F
Sbjct: 306 SCAKCKKKIT--GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 363
Query: 160 PRCARCSKTLTQGG--VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209
+C C + G + WH C VC CQ L G+ F S+ + P C
Sbjct: 364 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 415
Score = 87.4 bits (215), Expect = 1e-17
Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C++C + L + + +C PCYD +A +CA+C++ I + H H
Sbjct: 270 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVH 329
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
CF C C+ + + F ++ C Y F ++C C + G R LE G +W
Sbjct: 330 --CFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 387
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYC 150
H+ CF+C+ C+ L ++F K C
Sbjct: 388 HDTCFVCAICQINLEGKTFYSKKDRPLC 415
Score = 58.5 bits (140), Expect = 6e-09
Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 4/118 (3%)
Query: 156 NKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215
N P C +C K + + +H E VC+ C L F +C C+
Sbjct: 242 NGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDV 301
Query: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
+AP C+ CK+ I G+ + WH +CF+CA C T + + F + C+
Sbjct: 302 RYAPSCAKCKKKIT----GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE 355
Score = 28.9 bits (63), Expect = 5.2
Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 4/57 (7%)
Query: 219 PKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
P C C + I G+Y+ +H F C++C L GF + + C C
Sbjct: 246 PVCHQCHKVI----RGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 298
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 115 bits (289), Expect = 3e-26
Identities = 56/173 (32%), Positives = 83/173 (47%), Gaps = 4/173 (2%)
Query: 101 CSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAP 160
C C + + R L G +H F+CS C + L F +KGA +C PCY+ ++AP
Sbjct: 282 CHQCHKVIR--GRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 161 RCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPK 220
CA+C K +T + WH C C C+TP+ + F + PYC + ++F K
Sbjct: 340 SCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTK 399
Query: 221 CSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
C C I G +++ WH CF CA C +L G+ F D+ LC+
Sbjct: 400 CHGCDFKID--AGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCK 450
Score = 94.4 bits (233), Expect = 1e-19
Identities = 49/172 (28%), Positives = 77/172 (44%), Gaps = 6/172 (3%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
C +C ++I R L +H F C +C + L + F + + C CY ++
Sbjct: 282 CHQCHKVIR--GRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
C+ C + + + TWH HCF C+ C+ P+ +R+F ++G YC YE F
Sbjct: 340 SCAKCKKKIT--GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397
Query: 160 PRCARCSKTLTQGG--VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209
+C C + G + WH C VC CQ L G+ F S+ + P C
Sbjct: 398 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
Score = 87.4 bits (215), Expect = 1e-17
Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F C++C + L + + +C PCYD +A +CA+C++ I + H H
Sbjct: 304 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVH 363
Query: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
CF C C+ + + F ++ C Y F ++C C + G R LE G +W
Sbjct: 364 --CFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 421
Query: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYC 150
H+ CF+C+ C+ L ++F K C
Sbjct: 422 HDTCFVCAICQINLEGKTFYSKKDRPLC 449
Score = 58.5 bits (140), Expect = 6e-09
Identities = 31/118 (26%), Positives = 49/118 (41%), Gaps = 4/118 (3%)
Query: 156 NKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215
N P C +C K + + +H E VC+ C L F +C C+
Sbjct: 276 NGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDV 335
Query: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
+AP C+ CK+ I G+ + WH +CF+CA C T + + F + C+
Sbjct: 336 RYAPSCAKCKKKIT----GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE 389
Score = 28.9 bits (63), Expect = 5.2
Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 4/57 (7%)
Query: 219 PKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275
P C C + I G+Y+ +H F C++C L GF + + C C
Sbjct: 280 PVCHQCHKVI----RGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 332
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 115 bits (287), Expect = 6e-26
Identities = 68/257 (26%), Positives = 107/257 (41%), Gaps = 20/257 (7%)
Query: 17 RKYIQTDSGPYCVPCYDNTFAN--------TCAECQQLIGHDSRELFYEDRHFHEGCFRC 68
RK+ +T +G P ++N C CQ R + +HE CF C
Sbjct: 6 RKWGETGTGSGAAPAAALRWSNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVC 65
Query: 69 CRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFL 128
+C R + F + C + F+ C +CGE ++ R ++ WH CF
Sbjct: 66 AQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFII--GRVIKAMNNNWHPGCFR 123
Query: 129 CSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPR-----CARCSKTLTQGGVTYRDQPWHR 183
C C+ L FV + G H C PC+ + A C RC + + + +R +H
Sbjct: 124 CELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHP 183
Query: 184 ECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRH 243
+ CT C L + + E YC+ C ++ P C +C+RPI G+ V+ +
Sbjct: 184 DHFNCTHCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPI----EGRVVNALGKQ 238
Query: 244 WHHNCFSCARCSTSLVG 260
WH F CA+C +G
Sbjct: 239 WHVEHFVCAKCEKPFLG 255
Score = 112 bits (281), Expect = 3e-25
Identities = 74/282 (26%), Positives = 117/282 (41%), Gaps = 15/282 (5%)
Query: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
F CA+C + + + YC + FA C C + I R + + ++H G
Sbjct: 63 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120
Query: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQ-----CSACGETVMPGSRKLEYGG 119
CFRC C LAD F LC C+ + C C + + L +
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 178
Query: 120 QTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQ 179
+H F C+ C + L + + KG YC+PC++ P C C + + V +
Sbjct: 179 DAYHPDHFNCTHCGKELTAEAREL-KGELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 237
Query: 180 PWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSF 239
WH E VC C+ P G + + YC + +LF C +C I G VS
Sbjct: 238 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVI----EGDVVSA 293
Query: 240 EDRHWHHNCFSCARCSTSL-VGQGFVPDGDQVLCQGCSQAGP 280
++ W +CFSC+ C++ L + FV + +C+ C + P
Sbjct: 294 LNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFP 335
Score = 45.8 bits (107), Expect = 4e-05
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F CAKC + G ++ + YC Y+ F + C C +I D ++ +
Sbjct: 242 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSAL--NKAWC 299
Query: 63 EGCFRCCRCQRSLA-DEPFTCQDSELLCNDCY 93
CF C C L F D + +C CY
Sbjct: 300 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 331
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 114 bits (284), Expect = 1e-25
Identities = 67/252 (26%), Positives = 103/252 (40%), Gaps = 12/252 (4%)
Query: 14 LYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQR 73
LY R+ + P D C CQ R + +HE CF C +C R
Sbjct: 13 LYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELYHEHCFVCAQCFR 72
Query: 74 SLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCE 133
+ F + C + F+ C +CGE ++ R ++ WH CF C C+
Sbjct: 73 PFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFII--GRVIKAMNNNWHPGCFRCELCD 130
Query: 134 QPLGSRSFVPDKGAHYCVPCYENKFAPR-----CARCSKTLTQGGVTYRDQPWHRECLVC 188
L FV + G H C PC+ + A C RC + + + +R +H + C
Sbjct: 131 VELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNC 190
Query: 189 TGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNC 248
T C L + + E YC+ C ++ P C +C+RPI G+ V+ + WH
Sbjct: 191 THCGKELTAEARELKGE-LYCLPCHDKMGVPICGACRRPI----EGRVVNALGKQWHVEH 245
Query: 249 FSCARCSTSLVG 260
F CA+C +G
Sbjct: 246 FVCAKCEKPFLG 257
Score = 112 bits (281), Expect = 3e-25
Identities = 74/282 (26%), Positives = 117/282 (41%), Gaps = 15/282 (5%)
Query: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
F CA+C + + + YC + FA C C + I R + + ++H G
Sbjct: 65 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 122
Query: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQ-----CSACGETVMPGSRKLEYGG 119
CFRC C LAD F LC C+ + C C + + L +
Sbjct: 123 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 180
Query: 120 QTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQ 179
+H F C+ C + L + + KG YC+PC++ P C C + + V +
Sbjct: 181 DAYHPDHFNCTHCGKELTAEAREL-KGELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 239
Query: 180 PWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSF 239
WH E VC C+ P G + + YC + +LF C +C I G VS
Sbjct: 240 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVI----EGDVVSA 295
Query: 240 EDRHWHHNCFSCARCSTSL-VGQGFVPDGDQVLCQGCSQAGP 280
++ W +CFSC+ C++ L + FV + +C+ C + P
Sbjct: 296 LNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFP 337
Score = 45.8 bits (107), Expect = 4e-05
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F CAKC + G ++ + YC Y+ F + C C +I D ++ +
Sbjct: 244 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSAL--NKAWC 301
Query: 63 EGCFRCCRCQRSLA-DEPFTCQDSELLCNDCY 93
CF C C L F D + +C CY
Sbjct: 302 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 333
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 113 bits (282), Expect = 2e-25
Identities = 62/226 (27%), Positives = 96/226 (42%), Gaps = 12/226 (5%)
Query: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
C CQ R + +HE CF C +C R + F + C + F+
Sbjct: 10 CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 69
Query: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
C +CGE ++ R ++ WH CF C C+ L FV + G H C PC+ + A
Sbjct: 70 CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 127
Query: 160 PR-----CARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFG 214
C RC + + + +R +H + CT C L + + E YC+ C
Sbjct: 128 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGE-LYCLPCHD 186
Query: 215 ELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVG 260
++ P C +C+RPI G+ V+ + WH F CA+C +G
Sbjct: 187 KMGVPICGACRRPI----EGRVVNALGKQWHVEHFVCAKCEKPFLG 228
Score = 112 bits (281), Expect = 3e-25
Identities = 74/282 (26%), Positives = 117/282 (41%), Gaps = 15/282 (5%)
Query: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
F CA+C + + + YC + FA C C + I R + + ++H G
Sbjct: 36 FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 93
Query: 65 CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQ-----CSACGETVMPGSRKLEYGG 119
CFRC C LAD F LC C+ + C C + + L +
Sbjct: 94 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 151
Query: 120 QTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQ 179
+H F C+ C + L + + KG YC+PC++ P C C + + V +
Sbjct: 152 DAYHPDHFNCTHCGKELTAEAREL-KGELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 210
Query: 180 PWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSF 239
WH E VC C+ P G + + YC + +LF C +C I G VS
Sbjct: 211 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVI----EGDVVSA 266
Query: 240 EDRHWHHNCFSCARCSTSL-VGQGFVPDGDQVLCQGCSQAGP 280
++ W +CFSC+ C++ L + FV + +C+ C + P
Sbjct: 267 LNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFP 308
Score = 45.8 bits (107), Expect = 4e-05
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 3/92 (3%)
Query: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
E F CAKC + G ++ + YC Y+ F + C C +I D ++ +
Sbjct: 215 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSAL--NKAWC 272
Query: 63 EGCFRCCRCQRSLA-DEPFTCQDSELLCNDCY 93
CF C C L F D + +C CY
Sbjct: 273 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCY 304
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.497
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,641,405
Number of Sequences: 37866
Number of extensions: 742942
Number of successful extensions: 6709
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 132
Number of HSP's successfully gapped in prelim test: 572
Number of HSP's that attempted gapping in prelim test: 2810
Number of HSP's gapped (non-prelim): 2217
length of query: 280
length of database: 18,247,518
effective HSP length: 101
effective length of query: 179
effective length of database: 14,423,052
effective search space: 2581726308
effective search space used: 2581726308
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.